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Diff for /imach/src/imach.c between versions 1.200 and 1.209

version 1.200, 2015/09/09 16:53:55	version 1.209, 2015/11/17 22:12:03
Line 1	Line 1
/* $Id$	/* $Id$
$State$	$State$
$Log$	$Log$
	Revision 1.209 2015/11/17 22:12:03 brouard
	Summary: Adding ftolpl parameter
	Author: N Brouard

	We had difficulties to get smoothed confidence intervals. It was due
	to the period prevalence which wasn't computed accurately. The inner
	parameter ftolpl is now an outer parameter of the .imach parameter
	file after estepm. If ftolpl is small 1.e-4 and estepm too,
	computation are long.

	Revision 1.208 2015/11/17 14:31:57 brouard
	Summary: temporary

	Revision 1.207 2015/10/27 17:36:57 brouard
	* empty log message *

	Revision 1.206 2015/10/24 07:14:11 brouard
	* empty log message *

	Revision 1.205 2015/10/23 15:50:53 brouard
	Summary: 0.98r3 some clarification for graphs on likelihood contributions

	Revision 1.204 2015/10/01 16:20:26 brouard
	Summary: Some new graphs of contribution to likelihood

	Revision 1.203 2015/09/30 17:45:14 brouard
	Summary: looking at better estimation of the hessian

	Also a better criteria for convergence to the period prevalence And
	therefore adding the number of years needed to converge. (The
	prevalence in any alive state shold sum to one

	Revision 1.202 2015/09/22 19:45:16 brouard
	Summary: Adding some overall graph on contribution to likelihood. Might change

	Revision 1.201 2015/09/15 17:34:58 brouard
	Summary: 0.98r0

	- Some new graphs like suvival functions
	- Some bugs fixed like model=1+age+V2.

Revision 1.200 2015/09/09 16:53:55 brouard	Revision 1.200 2015/09/09 16:53:55 brouard
Summary: Big bug thanks to Flavia	Summary: Big bug thanks to Flavia

Line 638	Line 679

/* #define DEBUG */	/* #define DEBUG */
/* #define DEBUGBRENT */	/* #define DEBUGBRENT */
	/* #define DEBUGLINMIN */
	/* #define DEBUGHESS */
	#define DEBUGHESSIJ
	/* #define LINMINORIGINAL /\* Don't use loop on scale in linmin (accepting nan)\/ /
#define POWELL /* Instead of NLOPT */	#define POWELL /* Instead of NLOPT */
#define POWELLF1F3 /* Skip test */	#define POWELLF1F3 /* Skip test */
/* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test \/ /	/* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test \/ /
Line 729 typedef struct {	Line 774 typedef struct {
/* $State$ */	/* $State$ */
#include "version.h"	#include "version.h"
char version[]=__IMACH_VERSION__;	char version[]=__IMACH_VERSION__;
char copyright[]="September 2015,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015";	char copyright[]="October 2015,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015";
char fullversion[]="$Revision$ $Date$";	char fullversion[]="$Revision$ $Date$";
char strstart[80];	char strstart[80];
char optionfilext[10], optionfilefiname[FILENAMELENGTH];	char optionfilext[10], optionfilefiname[FILENAMELENGTH];
Line 796 char command[FILENAMELENGTH];	Line 841 char command[FILENAMELENGTH];
int outcmd=0;	int outcmd=0;

char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];	char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
	char fileresu[FILENAMELENGTH]; /* fileres without r in front */
char filelog[FILENAMELENGTH]; /* Log file */	char filelog[FILENAMELENGTH]; /* Log file */
char filerest[FILENAMELENGTH];	char filerest[FILENAMELENGTH];
char fileregp[FILENAMELENGTH];	char fileregp[FILENAMELENGTH];
Line 920 static int split( char path, char dirc	Line 965 static int split( char path, char dirc
}	}
/* got dirc from getcwd*/	/* got dirc from getcwd*/
printf(" DIRC = %s \n",dirc);	printf(" DIRC = %s \n",dirc);
} else { /* strip direcotry from path */	} else { /* strip directory from path */
ss++; /* after this, the filename */	ss++; /* after this, the filename */
l2 = strlen( ss ); /* length of filename */	l2 = strlen( ss ); /* length of filename */
if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );	if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
Line 1592 void linmin(double p[], double xi[], int	Line 1637 void linmin(double p[], double xi[], int
double xx,xmin,bx,ax;	double xx,xmin,bx,ax;
double fx,fb,fa;	double fx,fb,fa;

double scale=10., axs, xxs, xxss; /* Scale added for infinity */	#ifdef LINMINORIGINAL
	#else
	double scale=10., axs, xxs; /* Scale added for infinity */
	#endif

ncom=n;	ncom=n;
pcom=vector(1,n);	pcom=vector(1,n);
xicom=vector(1,n);	xicom=vector(1,n);
nrfunc=func;	nrfunc=func;
for (j=1;j<=n;j++) {	for (j=1;j<=n;j++) {
pcom[j]=p[j];	pcom[j]=p[j];
xicom[j]=xi[j];	xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
}	}

/* axs=0.0; */	#ifdef LINMINORIGINAL
/* xxss=1; /\* 1 and using scale \/ /	xx=1.;
xxs=1;	#else
/* do{ */	axs=0.0;
ax=0.;	xxs=1.;
	do{
xx= xxs;	xx= xxs;
	#endif
	ax=0.;
mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim); /* Outputs: xtx[j]=pcom[j]+(xx)xicom[j]; fx=f(xtx[j]) */	mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim); /* Outputs: xtx[j]=pcom[j]+(xx)xicom[j]; fx=f(xtx[j]) */
/* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */	/* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
/* xt[x,j]=pcom[j]+xxicom[j] f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 xi(j)) and f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j)) */	/* xt[x,j]=pcom[j]+xxicom[j] f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 xi(j)) and f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j)) */
Line 1616 void linmin(double p[], double xi[], int	Line 1667 void linmin(double p[], double xi[], int
/* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */	/* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
/* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */	/* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
/* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxsxi[j]] et non plus [0:xi[j]]/	/* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxsxi[j]] et non plus [0:xi[j]]/
/* if (fx != fx){ */	#ifdef LINMINORIGINAL
/* xxs=xxs/scale; /\* Trying a smaller xx, closer to initial ax=0 \/ /	#else
/* printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n", axs, xxs, fx,fb, fa, xx, ax, bx); */	if (fx != fx){
/* } */	xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
/* }while(fx != fx); */	printf("\|");
	fprintf(ficlog,"\|");
	#ifdef DEBUGLINMIN
	printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n", axs, xxs, fx,fb, fa, xx, ax, bx);
	#endif
	}
	}while(fx != fx);
	#endif

#ifdef DEBUGLINMIN	#ifdef DEBUGLINMIN
printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n", ax,xx,bx,fa,fx,fb);	printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n", ax,xx,bx,fa,fx,fb);
	fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n", ax,xx,bx,fa,fx,fb);
#endif	#endif
fret=brent(ax,xx,bx,f1dim,TOL,&xmin); / Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, fret(xmin),/	fret=brent(ax,xx,bx,f1dim,TOL,&xmin); / Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, fret(xmin),/
/* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */	/* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
Line 1636 void linmin(double p[], double xi[], int	Line 1695 void linmin(double p[], double xi[], int
#endif	#endif
#ifdef DEBUGLINMIN	#ifdef DEBUGLINMIN
printf("linmin end ");	printf("linmin end ");
	fprintf(ficlog,"linmin end ");
#endif	#endif
for (j=1;j<=n;j++) {	for (j=1;j<=n;j++) {
/* printf(" before xi[%d]=%12.8f", j,xi[j]); */	#ifdef LINMINORIGINAL
xi[j] = xmin; / xi rescaled by xmin: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */	xi[j] *= xmin;
/* if(xxs <1.0) */	#else
/* printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs ); */	#ifdef DEBUGLINMIN
	if(xxs <1.0)
	printf(" before xi[%d]=%12.8f", j,xi[j]);
	#endif
	xi[j] = xminxxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
	#ifdef DEBUGLINMIN
	if(xxs <1.0)
	printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
	#endif
	#endif
p[j] += xi[j]; /* Parameters values are updated accordingly */	p[j] += xi[j]; /* Parameters values are updated accordingly */
}	}
/* printf("\n"); */
#ifdef DEBUGLINMIN	#ifdef DEBUGLINMIN
	printf("\n");
printf("Comparing last frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, fret, (*func)(p));	printf("Comparing last frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, fret, (*func)(p));
	fprintf(ficlog,"Comparing last frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, fret, (*func)(p));
for (j=1;j<=n;j++) {	for (j=1;j<=n;j++) {
printf(" xi[%d]= %12.7f p[%d]= %12.7f",j,xi[j],j,p[j]);	printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
if(j % ncovmodel == 0)	fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
	if(j % ncovmodel == 0){
printf("\n");	printf("\n");
	fprintf(ficlog,"\n");
	}
}	}
	#else
#endif	#endif
free_vector(xicom,1,n);	free_vector(xicom,1,n);
free_vector(pcom,1,n);	free_vector(pcom,1,n);
Line 1685 void powell(double p[], double **xi, int	Line 1759 void powell(double p[], double **xi, int
xits=vector(1,n);	xits=vector(1,n);
fret=(func)(p);	fret=(func)(p);
for (j=1;j<=n;j++) pt[j]=p[j];	for (j=1;j<=n;j++) pt[j]=p[j];
rcurr_time = time(NULL);	rcurr_time = time(NULL);
for (iter=1;;++(iter)) {	for (iter=1;;++(iter)) {
fp=(fret); / From former iteration or initial value */	fp=(fret); / From former iteration or initial value */
ibig=0;	ibig=0;
Line 1729 void powell(double p[], double **xi, int	Line 1803 void powell(double p[], double **xi, int
for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */	for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
fptt=(*fret);	fptt=(*fret);
#ifdef DEBUG	#ifdef DEBUG
printf("fret=%lf, %lf, %lf \n", fret, fret, *fret);	printf("fret=%lf, %lf, %lf \n", fret, fret, *fret);
fprintf(ficlog, "fret=%lf, %lf, %lf \n", fret, fret, *fret);	fprintf(ficlog, "fret=%lf, %lf, %lf \n", fret, fret, *fret);
#endif	#endif
printf("%d",i);fflush(stdout); /* print direction (parameter) i */	printf("%d",i);fflush(stdout); /* print direction (parameter) i */
fprintf(ficlog,"%d",i);fflush(ficlog);	fprintf(ficlog,"%d",i);fflush(ficlog);
linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/	linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
/* Outputs are fret(new point p) p is updated and xit rescaled */	/* Outputs are fret(new point p) p is updated and xit rescaled */
Line 1830 void powell(double p[], double **xi, int	Line 1904 void powell(double p[], double **xi, int
t=2.0(fp-2.0(fret)+fptt)SQR(fp-(fret)-del); / Intel compiler doesn't work on one line; bug reported */	t=2.0(fp-2.0(fret)+fptt)SQR(fp-(fret)-del); / Intel compiler doesn't work on one line; bug reported */
t= t- del*SQR(fp-fptt);	t= t- del*SQR(fp-fptt);
#endif	#endif
directest = fp-2.0(fret)+fptt - 2.0 * del; /* If del was big enough we change it for a new direction */	directest = fp-2.0(fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
#ifdef DEBUG	#ifdef DEBUG
printf("t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0(fp-2.0(fret)+fptt)SQR(fp-(fret)-del),delSQR(fp-fptt),t,directest);	printf("t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0(fp-2.0(fret)+fptt)SQR(fp-(fret)-del),delSQR(fp-fptt),t,directest);
fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0(fp-2.0(fret)+fptt)SQR(fp-(fret)-del),delSQR(fp-fptt),t,directest);	fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0(fp-2.0(fret)+fptt)SQR(fp-(fret)-del),delSQR(fp-fptt),t,directest);
Line 1845 void powell(double p[], double **xi, int	Line 1919 void powell(double p[], double **xi, int
if (t < 0.0) { /* Then we use it for new direction */	if (t < 0.0) { /* Then we use it for new direction */
#else	#else
if (directestt < 0.0) { / Contradiction between both tests */	if (directestt < 0.0) { / Contradiction between both tests */
printf("directest= %.12lf, t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);	printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0(fret)+fptt, fp -(*fret) -del, fp-fptt);	printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0(fret)+fptt, fp -(*fret) -del, fp-fptt);
fprintf(ficlog,"directest= %.12lf, t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);	fprintf(ficlog,"directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0(fret)+fptt, fp -(*fret) -del, fp-fptt);	fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0(fret)+fptt, fp -(*fret) -del, fp-fptt);
}	}
if (directest < 0.0) { /* Then we use it for new direction */	if (directest < 0.0) { /* Then we use it for new direction */
Line 1855 void powell(double p[], double **xi, int	Line 1929 void powell(double p[], double **xi, int
#ifdef DEBUGLINMIN	#ifdef DEBUGLINMIN
printf("Before linmin in direction P%d-P0\n",n);	printf("Before linmin in direction P%d-P0\n",n);
for (j=1;j<=n;j++) {	for (j=1;j<=n;j++) {
printf("Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);	printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
if(j % ncovmodel == 0)	fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
	if(j % ncovmodel == 0){
printf("\n");	printf("\n");
	fprintf(ficlog,"\n");
	}
}	}
#endif	#endif
linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/	linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
#ifdef DEBUGLINMIN	#ifdef DEBUGLINMIN
for (j=1;j<=n;j++) {	for (j=1;j<=n;j++) {
printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);	printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
if(j % ncovmodel == 0)	fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
	if(j % ncovmodel == 0){
printf("\n");	printf("\n");
	fprintf(ficlog,"\n");
	}
}	}
#endif	#endif
for (j=1;j<=n;j++) {	for (j=1;j<=n;j++) {
Line 1895 void powell(double p[], double **xi, int	Line 1975 void powell(double p[], double **xi, int

/** Prevalence limit (stable or period prevalence) **************/	/** Prevalence limit (stable or period prevalence) **************/

double prevalim(double prlim, int nlstate, double x[], double age, double oldm, double savm, double ftolpl, int ij)	double prevalim(double prlim, int nlstate, double x[], double age, double oldm, double savm, double ftolpl, int *ncvyear, int ij)
{	{
/* Computes the prevalence limit in each live state at age x by left multiplying the unit	/* Computes the prevalence limit in each live state at age x by left multiplying the unit
matrix by transitions matrix until convergence is reached */	matrix by transitions matrix until convergence is reached with precision ftolpl */
	/* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1 = Wx-n Px-n ... Px-2 Px-1 I */
	/* Wx is row vector: population in state 1, population in state 2, population dead */
	/* or prevalence in state 1, prevalence in state 2, 0 */
	/* newm is the matrix after multiplications, its rows are identical at a factor */
	/* Initial matrix pimij */
	/* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
	/* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
	/* 0, 0 , 1} */
	/*
	* and after some iteration: */
	/* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
	/* 0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
	/* 0, 0 , 1} */
	/* And prevalence by suppressing the deaths are close to identical rows in prlim: */
	/* {0.51571254859325999, 0.4842874514067399, */
	/* 0.51326036147820708, 0.48673963852179264} */
	/* If we start from prlim again, prlim tends to a constant matrix */

int i, ii,j,k;	int i, ii,j,k;
double min, max, maxmin, maxmax,sumnew=0.;	double min, max, *meandiff, maxmax,sumnew=0.;
/* double *matprod2(); / /* test */	/* double *matprod2(); / /* test */
double out, cov[NCOVMAX+1], pmij();	double out, cov[NCOVMAX+1], pmij();
double **newm;	double **newm;
double agefin, delaymax=50 ; /* Max number of years to converge */	double agefin, delaymax=200. ; /* 100 Max number of years to converge */
	int ncvloop=0;

	min=vector(1,nlstate);
	max=vector(1,nlstate);
	meandiff=vector(1,nlstate);

for (ii=1;ii<=nlstate+ndeath;ii++)	for (ii=1;ii<=nlstate+ndeath;ii++)
for (j=1;j<=nlstate+ndeath;j++){	for (j=1;j<=nlstate+ndeath;j++){
oldm[ii][j]=(ii==j ? 1.0 : 0.0);	oldm[ii][j]=(ii==j ? 1.0 : 0.0);
Line 1915 double prevalim(double prlim, int nl	Line 2017 double prevalim(double prlim, int nl
cov[1]=1.;	cov[1]=1.;

/* Even if hstepm = 1, at least one multiplication by the unit matrix */	/* Even if hstepm = 1, at least one multiplication by the unit matrix */
	/* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){	for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
	ncvloop++;
newm=savm;	newm=savm;
/* Covariates have to be included here again */	/* Covariates have to be included here again */
cov[2]=agefin;	cov[2]=agefin;
Line 1942 double prevalim(double prlim, int nl	Line 2046 double prevalim(double prlim, int nl

savm=oldm;	savm=oldm;
oldm=newm;	oldm=newm;
maxmax=0.;
for(j=1;j<=nlstate;j++){	for(j=1; j<=nlstate; j++){
min=1.;	max[j]=0.;
max=0.;	min[j]=1.;
for(i=1; i<=nlstate; i++) {	}
sumnew=0;	for(i=1;i<=nlstate;i++){
for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];	sumnew=0;
	for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
	for(j=1; j<=nlstate; j++){
prlim[i][j]= newm[i][j]/(1-sumnew);	prlim[i][j]= newm[i][j]/(1-sumnew);
/printf(" prevalim i=%d, j=%d, prmlim[%d][%d]=%f, agefin=%d \n", i, j, i, j, prlim[i][j],(int)agefin);/	max[j]=FMAX(max[j],prlim[i][j]);
max=FMAX(max,prlim[i][j]);	min[j]=FMIN(min[j],prlim[i][j]);
min=FMIN(min,prlim[i][j]);
}	}
maxmin=max-min;	}
maxmax=FMAX(maxmax,maxmin);
	maxmax=0.;
	for(j=1; j<=nlstate; j++){
	meandiff[j]=(max[j]-min[j])/(max[j]+min[j])2.; / mean difference for each column */
	maxmax=FMAX(maxmax,meandiff[j]);
	/* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
} /* j loop */	} /* j loop */
	*ncvyear= (int)age- (int)agefin;
	/* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, ncvyear); /
if(maxmax < ftolpl){	if(maxmax < ftolpl){
	/* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, ncvyear); /
	free_vector(min,1,nlstate);
	free_vector(max,1,nlstate);
	free_vector(meandiff,1,nlstate);
return prlim;	return prlim;
}	}
} /* age loop */	} /* age loop */
	/* After some age loop it doesn't converge */
	printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
	Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
	/* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
	free_vector(min,1,nlstate);
	free_vector(max,1,nlstate);
	free_vector(meandiff,1,nlstate);

return prlim; /* should not reach here */	return prlim; /* should not reach here */
}	}

Line 2536 double funcone( double *x)	Line 2660 double funcone( double *x)
ll[s[mw[mi][i]][i]] += 2weight[i]lli;	ll[s[mw[mi][i]][i]] += 2weight[i]lli;
/printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); /	/printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); /
if(globpr){	if(globpr){
fprintf(ficresilk,"%9ld %6d %2d %2d %1d %1d %3d %11.6f %8.4f\	fprintf(ficresilk,"%9ld %6.1f %6d %2d %2d %2d %2d %3d %11.6f %8.4f %8.3f\
%11.6f %11.6f %11.6f ", \	%11.6f %11.6f %11.6f ", \
num[i],i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],	num[i], agexact, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
2weight[i]lli,out[s1][s2],savm[s1][s2]);	2weight[i]lli,out[s1][s2],savm[s1][s2]);
for(k=1,llt=0.,l=0.; k<=nlstate; k++){	for(k=1,llt=0.,l=0.; k<=nlstate; k++){
llt +=ll[k]*gipmx/gsw;	llt +=ll[k]*gipmx/gsw;
Line 2570 void likelione(FILE *ficres,double p[],	Line 2694 void likelione(FILE *ficres,double p[],
int k;	int k;

if(globpri !=0){ / Just counts and sums, no printings */	if(globpri !=0){ / Just counts and sums, no printings */
strcpy(fileresilk,"ilk");	strcpy(fileresilk,"ILK_");
strcat(fileresilk,fileres);	strcat(fileresilk,fileresu);
if((ficresilk=fopen(fileresilk,"w"))==NULL) {	if((ficresilk=fopen(fileresilk,"w"))==NULL) {
printf("Problem with resultfile: %s\n", fileresilk);	printf("Problem with resultfile: %s\n", fileresilk);
fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);	fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
}	}
fprintf(ficresilk, "#individual(line's_record) s1 s2 wave# effective_wave# number_of_matrices_product pij weight -2ln(pij)weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2llweightXnumber_of_contribs/sum_of_weights) and_total\n");	fprintf(ficresilk, "#individual(line's_record) count age s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2llweightXnumber_of_contribs/sum_of_weights) and_total\n");
fprintf(ficresilk, "#num_i i s1 s2 mi mw dh likeli weight 2wlli out sav ");	fprintf(ficresilk, "#num_i age i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
/* i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2weight[i]lli,out[s1][s2],savm[s1][s2]); */	/* i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2weight[i]lli,out[s1][s2],savm[s1][s2]); */
for(k=1; k<=nlstate; k++)	for(k=1; k<=nlstate; k++)
fprintf(ficresilk," -2gipw/gswweight*ll[%d]++",k);	fprintf(ficresilk," -2gipw/gswweight*ll[%d]++",k);
Line 2587 void likelione(FILE *ficres,double p[],	Line 2711 void likelione(FILE *ficres,double p[],
fretone=(funcone)(p);	fretone=(funcone)(p);
if(*globpri !=0){	if(*globpri !=0){
fclose(ficresilk);	fclose(ficresilk);
fprintf(fichtm,"\n<br>File of contributions to the likelihood: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));	if (mle ==0)
fflush(fichtm);	fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
}	else if(mle >=1)
	fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
	fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));


	for (k=1; k<= nlstate ; k++) {
	fprintf(fichtm,"<br>- Probability p%dj by origin %d and destination j <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
	<img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
	}
	fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
	<img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
	fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
	<img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
	fflush(fichtm);
	}
return;	return;
}	}

Line 2620 void mlikeli(FILE *ficres,double p[], in	Line 2758 void mlikeli(FILE *ficres,double p[], in
for (j=1;j<=npar;j++)	for (j=1;j<=npar;j++)
xi[i][j]=(i==j ? 1.0 : 0.0);	xi[i][j]=(i==j ? 1.0 : 0.0);
printf("Powell\n"); fprintf(ficlog,"Powell\n");	printf("Powell\n"); fprintf(ficlog,"Powell\n");
strcpy(filerespow,"pow");	strcpy(filerespow,"POW_");
strcat(filerespow,fileres);	strcat(filerespow,fileres);
if((ficrespow=fopen(filerespow,"w"))==NULL) {	if((ficrespow=fopen(filerespow,"w"))==NULL) {
printf("Problem with resultfile: %s\n", filerespow);	printf("Problem with resultfile: %s\n", filerespow);
Line 2663 void mlikeli(FILE *ficres,double p[], in	Line 2801 void mlikeli(FILE *ficres,double p[], in
#endif	#endif
free_matrix(xi,1,npar,1,npar);	free_matrix(xi,1,npar,1,npar);
fclose(ficrespow);	fclose(ficrespow);
printf("#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));	printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
fprintf(ficlog,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));	fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));	fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));

}	}

/** Computes Hessian and covariance matrix */	/** Computes Hessian and covariance matrix */
void hesscov(double *matcov, double p[], int npar, double delti[], double ftolhess, double (func)(double []))	void hesscov(double matcov, double hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
{	{
double a,y,*x,pd;	double a,y,*x,pd;
double **hess;	/* double *hess; /
int i, j;	int i, j;
int *indx;	int *indx;

double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);	double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
double hessij(double p[], double delti[], int i, int j,double (*func)(double []),int npar);	double hessij(double p[], double *hess, double delti[], int i, int j,double (func)(double []),int npar);
void lubksb(double *a, int npar, int indx, double b[]) ;	void lubksb(double *a, int npar, int indx, double b[]) ;
void ludcmp(double *a, int npar, int indx, double *d) ;	void ludcmp(double *a, int npar, int indx, double *d) ;
double gompertz(double p[]);	double gompertz(double p[]);
hess=matrix(1,npar,1,npar);	/* hess=matrix(1,npar,1,npar); */

printf("\nCalculation of the hessian matrix. Wait...\n");	printf("\nCalculation of the hessian matrix. Wait...\n");
fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");	fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
for (i=1;i<=npar;i++){	for (i=1;i<=npar;i++){
printf("%d",i);fflush(stdout);	printf("%d-",i);fflush(stdout);
fprintf(ficlog,"%d",i);fflush(ficlog);	fprintf(ficlog,"%d-",i);fflush(ficlog);

hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);	hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);

Line 2699 void hesscov(double **matcov, double p[]	Line 2837 void hesscov(double **matcov, double p[]
for (i=1;i<=npar;i++) {	for (i=1;i<=npar;i++) {
for (j=1;j<=npar;j++) {	for (j=1;j<=npar;j++) {
if (j>i) {	if (j>i) {
printf(".%d%d",i,j);fflush(stdout);	printf(".%d-%d",i,j);fflush(stdout);
fprintf(ficlog,".%d%d",i,j);fflush(ficlog);	fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
hess[i][j]=hessij(p,delti,i,j,func,npar);	hess[i][j]=hessij(p,hess, delti,i,j,func,npar);

hess[j][i]=hess[i][j];	hess[j][i]=hess[i][j];
/printf(" %lf ",hess[i][j]);/	/printf(" %lf ",hess[i][j]);/
Line 2735 void hesscov(double **matcov, double p[]	Line 2873 void hesscov(double **matcov, double p[]
fprintf(ficlog,"\n#Hessian matrix#\n");	fprintf(ficlog,"\n#Hessian matrix#\n");
for (i=1;i<=npar;i++) {	for (i=1;i<=npar;i++) {
for (j=1;j<=npar;j++) {	for (j=1;j<=npar;j++) {
printf("%.3e ",hess[i][j]);	printf("%.6e ",hess[i][j]);
fprintf(ficlog,"%.3e ",hess[i][j]);	fprintf(ficlog,"%.6e ",hess[i][j]);
}	}
printf("\n");	printf("\n");
fprintf(ficlog,"\n");	fprintf(ficlog,"\n");
}	}

	/* printf("\n#Covariance matrix#\n"); */
	/* fprintf(ficlog,"\n#Covariance matrix#\n"); */
	/* for (i=1;i<=npar;i++) { */
	/* for (j=1;j<=npar;j++) { */
	/* printf("%.6e ",matcov[i][j]); */
	/* fprintf(ficlog,"%.6e ",matcov[i][j]); */
	/* } */
	/* printf("\n"); */
	/* fprintf(ficlog,"\n"); */
	/* } */

/* Recompute Inverse */	/* Recompute Inverse */
for (i=1;i<=npar;i++)	/* for (i=1;i<=npar;i++) */
for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];	/* for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
ludcmp(a,npar,indx,&pd);	/* ludcmp(a,npar,indx,&pd); */

	/* printf("\n#Hessian matrix recomputed#\n"); */

	/* for (j=1;j<=npar;j++) { */
	/* for (i=1;i<=npar;i++) x[i]=0; */
	/* x[j]=1; */
	/* lubksb(a,npar,indx,x); */
	/* for (i=1;i<=npar;i++){ */
	/* y[i][j]=x[i]; */
	/* printf("%.3e ",y[i][j]); */
	/* fprintf(ficlog,"%.3e ",y[i][j]); */
	/* } */
	/* printf("\n"); */
	/* fprintf(ficlog,"\n"); */
	/* } */

	/* Verifying the inverse matrix */
	#ifdef DEBUGHESS
	y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);

/* printf("\n#Hessian matrix recomputed#\n");	printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
	fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");

for (j=1;j<=npar;j++) {	for (j=1;j<=npar;j++) {
for (i=1;i<=npar;i++) x[i]=0;
x[j]=1;
lubksb(a,npar,indx,x);
for (i=1;i<=npar;i++){	for (i=1;i<=npar;i++){
y[i][j]=x[i];	printf("%.2f ",y[i][j]);
printf("%.3e ",y[i][j]);	fprintf(ficlog,"%.2f ",y[i][j]);
fprintf(ficlog,"%.3e ",y[i][j]);
}	}
printf("\n");	printf("\n");
fprintf(ficlog,"\n");	fprintf(ficlog,"\n");
}	}
*/	#endif

free_matrix(a,1,npar,1,npar);	free_matrix(a,1,npar,1,npar);
free_matrix(y,1,npar,1,npar);	free_matrix(y,1,npar,1,npar);
free_vector(x,1,npar);	free_vector(x,1,npar);
free_ivector(indx,1,npar);	free_ivector(indx,1,npar);
free_matrix(hess,1,npar,1,npar);	/* free_matrix(hess,1,npar,1,npar); */


}	}

/************* hessian matrix **************/	/************* hessian matrix **************/
double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)	double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
{	{ /* Around values of x, computes the function func and returns the scales delti and hessian */
int i;	int i;
int l=1, lmax=20;	int l=1, lmax=20;
double k1,k2;	double k1,k2, res, fx;
double p2[MAXPARM+1]; /* identical to x */	double p2[MAXPARM+1]; /* identical to x */
double res;
double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;	double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
double fx;
int k=0,kmax=10;	int k=0,kmax=10;
double l1;	double l1;

Line 2797 double hessii(double x[], double delta,	Line 2960 double hessii(double x[], double delta,
p2[theta]=x[theta]-delt;	p2[theta]=x[theta]-delt;
k2=func(p2)-fx;	k2=func(p2)-fx;
/res= (k1-2.0fx+k2)/delt/delt; */	/res= (k1-2.0fx+k2)/delt/delt; */
res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2L /	res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2L /

#ifdef DEBUGHESS	#ifdef DEBUGHESSII
printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);	printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);	fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
#endif	#endif
Line 2813 double hessii(double x[], double delta,	Line 2976 double hessii(double x[], double delta,
else if((k1 >khi/nkhi) \|\| (k2 >khi/nkhi)){	else if((k1 >khi/nkhi) \|\| (k2 >khi/nkhi)){
delts=delt;	delts=delt;
}	}
}	} /* End loop k */
}	}
delti[theta]=delts;	delti[theta]=delts;
return res;	return res;

}	}

double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar)	double hessij( double x[], double *hess, double delti[], int thetai,int thetaj,double (func)(double []),int npar)
{	{
int i;	int i;
int l=1, lmax=20;	int l=1, lmax=20;
double k1,k2,k3,k4,res,fx;	double k1,k2,k3,k4,res,fx;
double p2[MAXPARM+1];	double p2[MAXPARM+1];
int k;	int k, kmax=1;
	double v1, v2, cv12, lc1, lc2;

	int firstime=0;

fx=func(x);	fx=func(x);
for (k=1; k<=2; k++) {	for (k=1; k<=kmax; k=k+10) {
for (i=1;i<=npar;i++) p2[i]=x[i];	for (i=1;i<=npar;i++) p2[i]=x[i];
p2[thetai]=x[thetai]+delti[thetai]/k;	p2[thetai]=x[thetai]+delti[thetai]*k;
p2[thetaj]=x[thetaj]+delti[thetaj]/k;	p2[thetaj]=x[thetaj]+delti[thetaj]*k;
k1=func(p2)-fx;	k1=func(p2)-fx;

p2[thetai]=x[thetai]+delti[thetai]/k;	p2[thetai]=x[thetai]+delti[thetai]*k;
p2[thetaj]=x[thetaj]-delti[thetaj]/k;	p2[thetaj]=x[thetaj]-delti[thetaj]*k;
k2=func(p2)-fx;	k2=func(p2)-fx;

p2[thetai]=x[thetai]-delti[thetai]/k;	p2[thetai]=x[thetai]-delti[thetai]*k;
p2[thetaj]=x[thetaj]+delti[thetaj]/k;	p2[thetaj]=x[thetaj]+delti[thetaj]*k;
k3=func(p2)-fx;	k3=func(p2)-fx;

p2[thetai]=x[thetai]-delti[thetai]/k;	p2[thetai]=x[thetai]-delti[thetai]*k;
p2[thetaj]=x[thetaj]-delti[thetaj]/k;	p2[thetaj]=x[thetaj]-delti[thetaj]*k;
k4=func(p2)-fx;	k4=func(p2)-fx;
res=(k1-k2-k3+k4)/4.0/delti[thetai]k/delti[thetaj]k/2.; /* Because of L not 2L /	res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2L /
#ifdef DEBUG	if(k1k2k3*k4 <0.){
printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);	firstime=1;
fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);	kmax=kmax+10;
	}
	if(kmax >=10 \|\| firstime ==1){
	printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; increase ftol=%.2e\n",thetai,thetaj, ftol);
	fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; increase ftol=%.2e\n",thetai,thetaj, ftol);
	printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e deltik=%.12e deltjk=%.12e, xi-dek=%.12e xj-dek=%.12e res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
	fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e deltik=%.12e deltjk=%.12e, xi-dek=%.12e xj-dek=%.12e res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
	}
	#ifdef DEBUGHESSIJ
	v1=hess[thetai][thetai];
	v2=hess[thetaj][thetaj];
	cv12=res;
	/* Computing eigen value of Hessian matrix */
	lc1=((v1+v2)+sqrt((v1+v2)(v1+v2) - 4(v1v2-cv12cv12)))/2.;
	lc2=((v1+v2)-sqrt((v1+v2)(v1+v2) - 4(v1v2-cv12cv12)))/2.;
	if ((lc2 <0) \|\| (lc1 <0) ){
	printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
	fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
	printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
	fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
	}
#endif	#endif
}	}
return res;	return res;
}	}

	/* Not done yet: Was supposed to fix if not exactly at the maximum */
	/* double hessij( double x[], double delti[], int thetai,int thetaj,double (func)(double []),int npar) /
	/* { */
	/* int i; */
	/* int l=1, lmax=20; */
	/* double k1,k2,k3,k4,res,fx; */
	/* double p2[MAXPARM+1]; */
	/* double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
	/* int k=0,kmax=10; */
	/* double l1; */

	/* fx=func(x); */
	/* for(l=0 ; l <=lmax; l++){ /\* Enlarging the zone around the Maximum \/ /
	/* l1=pow(10,l); */
	/* delts=delt; */
	/* for(k=1 ; k <kmax; k=k+1){ */
	/* delt = delti(l1k); */
	/* for (i=1;i<=npar;i++) p2[i]=x[i]; */
	/* p2[thetai]=x[thetai]+delti[thetai]/k; */
	/* p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
	/* k1=func(p2)-fx; */

	/* p2[thetai]=x[thetai]+delti[thetai]/k; */
	/* p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
	/* k2=func(p2)-fx; */

	/* p2[thetai]=x[thetai]-delti[thetai]/k; */
	/* p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
	/* k3=func(p2)-fx; */

	/* p2[thetai]=x[thetai]-delti[thetai]/k; */
	/* p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
	/* k4=func(p2)-fx; */
	/* res=(k1-k2-k3+k4)/4.0/delti[thetai]k/delti[thetaj]k/2.; /\* Because of L not 2L \/ */
	/* #ifdef DEBUGHESSIJ */
	/* printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
	/* fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
	/* #endif */
	/* if((k1 <khi/nkhi/2.) \|\| (k2 <khi/nkhi/2.)\|\| (k4 <khi/nkhi/2.)\|\| (k4 <khi/nkhi/2.)){ */
	/* k=kmax; */
	/* } */
	/* else if((k1 >khi/nkhif) \|\| (k2 >khi/nkhif) \|\| (k4 >khi/nkhif) \|\| (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. \/ /
	/* k=kmax; l=lmax10; /
	/* } */
	/* else if((k1 >khi/nkhi) \|\| (k2 >khi/nkhi)){ */
	/* delts=delt; */
	/* } */
	/* } /\* End loop k \/ /
	/* } */
	/* delti[theta]=delts; */
	/* return res; */
	/* } */


/************ Inverse of matrix ************/	/************ Inverse of matrix ************/
void ludcmp(double *a, int n, int indx, double *d)	void ludcmp(double *a, int n, int indx, double *d)
{	{
Line 2947 void freqsummary(char fileres[], int ia	Line 3187 void freqsummary(char fileres[], int ia

pp=vector(1,nlstate);	pp=vector(1,nlstate);
prop=matrix(1,nlstate,iagemin,iagemax+3);	prop=matrix(1,nlstate,iagemin,iagemax+3);
strcpy(fileresp,"p");	strcpy(fileresp,"P_");
strcat(fileresp,fileres);	strcat(fileresp,fileresu);
if((ficresp=fopen(fileresp,"w"))==NULL) {	if((ficresp=fopen(fileresp,"w"))==NULL) {
printf("Problem with prevalence resultfile: %s\n", fileresp);	printf("Problem with prevalence resultfile: %s\n", fileresp);
fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);	fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
Line 3787 void cvevsij(double ***eij, double x[],	Line 4027 void cvevsij(double ***eij, double x[],
}	}

/********** Variance ****************/	/********** Variance ****************/
void varevsij(char optionfilefiname[], double *vareij, double matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double oldm, double savm, double **prlim, double ftolpl, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])	void varevsij(char optionfilefiname[], double *vareij, double matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double oldm, double savm, double *prlim, double ftolpl, int ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])
{	{
/* Variance of health expectancies */	/* Variance of health expectancies */
/* double prevalim(double prlim, int nlstate, double xp, double age, double oldm, double * savm,double ftolpl);*/	/* double prevalim(double prlim, int nlstate, double xp, double age, double oldm, double * savm,double ftolpl);*/
Line 3816 void varevsij(char optionfilefiname[], d	Line 4056 void varevsij(char optionfilefiname[], d

if(popbased==1){	if(popbased==1){
if(mobilav!=0)	if(mobilav!=0)
strcpy(digitp,"-populbased-mobilav-");	strcpy(digitp,"-POPULBASED-MOBILAV_");
else strcpy(digitp,"-populbased-nomobil-");	else strcpy(digitp,"-POPULBASED-NOMOBIL_");
}	}
else	else
strcpy(digitp,"-stablbased-");	strcpy(digitp,"-STABLBASED_");

if (mobilav!=0) {	if (mobilav!=0) {
mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);	mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
Line 3830 void varevsij(char optionfilefiname[], d	Line 4070 void varevsij(char optionfilefiname[], d
}	}
}	}

strcpy(fileresprobmorprev,"prmorprev");	strcpy(fileresprobmorprev,"PRMORPREV-");
sprintf(digit,"%-d",ij);	sprintf(digit,"%-d",ij);
/printf("DIGIT=%s, ij=%d ijr=%-d\|\n",digit, ij,ij);/	/printf("DIGIT=%s, ij=%d ijr=%-d\|\n",digit, ij,ij);/
strcat(fileresprobmorprev,digit); /* Tvar to be done */	strcat(fileresprobmorprev,digit); /* Tvar to be done */
strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */	strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
strcat(fileresprobmorprev,fileres);	strcat(fileresprobmorprev,fileresu);
if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {	if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
printf("Problem with resultfile: %s\n", fileresprobmorprev);	printf("Problem with resultfile: %s\n", fileresprobmorprev);
fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);	fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
}	}
printf("Computing total mortality p.j=w1p1j+w2p2j+..: result on file '%s' \n",fileresprobmorprev);	printf("Computing total mortality p.j=w1p1j+w2p2j+..: result on file '%s' \n",fileresprobmorprev);

fprintf(ficlog,"Computing total mortality p.j=w1p1j+w2p2j+..: result on file '%s' \n",fileresprobmorprev);	fprintf(ficlog,"Computing total mortality p.j=w1p1j+w2p2j+..: result on file '%s' \n",fileresprobmorprev);
pstamp(ficresprobmorprev);	pstamp(ficresprobmorprev);
fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1p1j+w2p2j+... stand dev in()\n",estepm);	fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1p1j+w2p2j+... stand dev in()\n",estepm);
Line 3852 void varevsij(char optionfilefiname[], d	Line 4091 void varevsij(char optionfilefiname[], d
fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);	fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
}	}
fprintf(ficresprobmorprev,"\n");	fprintf(ficresprobmorprev,"\n");

fprintf(ficgp,"\n# Routine varevsij");	fprintf(ficgp,"\n# Routine varevsij");
fprintf(ficgp,"\nunset title \n");	fprintf(ficgp,"\nunset title \n");
/* fprintf(fichtm, "#Local time at start: %s", strstart);*/	/* fprintf(fichtm, "#Local time at start: %s", strstart);*/
Line 3889 void varevsij(char optionfilefiname[], d	Line 4129 void varevsij(char optionfilefiname[], d
/* For example we decided to compute the life expectancy with the smallest unit */	/* For example we decided to compute the life expectancy with the smallest unit */
/* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.	/* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.
nhstepm is the number of hstepm from age to agelim	nhstepm is the number of hstepm from age to agelim
nstepm is the number of stepm from age to agelin.	nstepm is the number of stepm from age to agelim.
Look at function hpijx to understand why (it is linked to memory size questions) */	Look at function hpijx to understand why because of memory size limitations,
/* We decided (b) to get a life expectancy respecting the most precise curvature of the	we decided (b) to get a life expectancy respecting the most precise curvature of the
survival function given by stepm (the optimization length). Unfortunately it	survival function given by stepm (the optimization length). Unfortunately it
means that if the survival funtion is printed every two years of age and if	means that if the survival funtion is printed every two years of age and if
you sum them up and add 1 year (area under the trapezoids) you won't get the same	you sum them up and add 1 year (area under the trapezoids) you won't get the same
Line 3912 void varevsij(char optionfilefiname[], d	Line 4152 void varevsij(char optionfilefiname[], d
for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/	for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
xp[i] = x[i] + (i==theta ?delti[theta]:0);	xp[i] = x[i] + (i==theta ?delti[theta]:0);
}	}
hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);
prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);	prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);

if (popbased==1) {	if (popbased==1) {
if(mobilav ==0){	if(mobilav ==0){
Line 3925 void varevsij(char optionfilefiname[], d	Line 4165 void varevsij(char optionfilefiname[], d
}	}
}	}

	hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij); /* Returns p3mat[i][j][h] for h=1 to nhstepm */
for(j=1; j<= nlstate; j++){	for(j=1; j<= nlstate; j++){
for(h=0; h<=nhstepm; h++){	for(h=0; h<=nhstepm; h++){
for(i=1, gp[h][j]=0.;i<=nlstate;i++)	for(i=1, gp[h][j]=0.;i<=nlstate;i++)
gp[h][j] += prlim[i][i]*p3mat[i][j][h];	gp[h][j] += prlim[i][i]*p3mat[i][j][h];
}	}
}	}
/* This for computing probability of death (h=1 means	/* Next for computing probability of death (h=1 means
computed over hstepm matrices product = hstepm*stepm months)	computed over hstepm matrices product = hstepm*stepm months)
as a weighted average of prlim.	as a weighted average of prlim.
*/	*/
Line 3943 void varevsij(char optionfilefiname[], d	Line 4184 void varevsij(char optionfilefiname[], d

for(i=1; i<=npar; i++) /* Computes gradient x - delta */	for(i=1; i<=npar; i++) /* Computes gradient x - delta */
xp[i] = x[i] - (i==theta ?delti[theta]:0);	xp[i] = x[i] - (i==theta ?delti[theta]:0);
hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);
prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);	prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij);

if (popbased==1) {	if (popbased==1) {
if(mobilav ==0){	if(mobilav ==0){
Line 3956 void varevsij(char optionfilefiname[], d	Line 4197 void varevsij(char optionfilefiname[], d
}	}
}	}

	hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);

for(j=1; j<= nlstate; j++){ /* Sum of wi * eij = e.j */	for(j=1; j<= nlstate; j++){ /* Sum of wi * eij = e.j */
for(h=0; h<=nhstepm; h++){	for(h=0; h<=nhstepm; h++){
for(i=1, gm[h][j]=0.;i<=nlstate;i++)	for(i=1, gm[h][j]=0.;i<=nlstate;i++)
Line 4018 void varevsij(char optionfilefiname[], d	Line 4261 void varevsij(char optionfilefiname[], d
varppt[j][i]=doldmp[j][i];	varppt[j][i]=doldmp[j][i];
/* end ppptj */	/* end ppptj */
/* x centered again */	/* x centered again */
hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);
prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ij);	prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij);

if (popbased==1) {	if (popbased==1) {
if(mobilav ==0){	if(mobilav ==0){
Line 4035 void varevsij(char optionfilefiname[], d	Line 4278 void varevsij(char optionfilefiname[], d
computed over hstepm (estepm) matrices product = hstepm*stepm months)	computed over hstepm (estepm) matrices product = hstepm*stepm months)
as a weighted average of prlim.	as a weighted average of prlim.
*/	*/
	hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);
for(j=nlstate+1;j<=nlstate+ndeath;j++){	for(j=nlstate+1;j<=nlstate+ndeath;j++){
for(i=1,gmp[j]=0.;i<= nlstate; i++)	for(i=1,gmp[j]=0.;i<= nlstate; i++)
gmp[j] += prlim[i][i]*p3mat[i][j][1];	gmp[j] += prlim[i][i]*p3mat[i][j][1];
Line 4070 void varevsij(char optionfilefiname[], d	Line 4314 void varevsij(char optionfilefiname[], d
fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");	fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
/* for(j=nlstate+1; j<= nlstate+ndeath; j++){ // Only the first actually */	/* for(j=nlstate+1; j<= nlstate+ndeath; j++){ // Only the first actually */
fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");	fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);	fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
/* fprintf(ficgp,"\n plot \"%s\" u 1:($3%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); /	/* fprintf(ficgp,"\n plot \"%s\" u 1:($3%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); /
/* fprintf(ficgp,"\n replot \"%s\" u 1:(($3+1.96$4)%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */	/* fprintf(ficgp,"\n replot \"%s\" u 1:(($3+1.96$4)%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
/* fprintf(ficgp,"\n replot \"%s\" u 1:(($3-1.96$4)%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */	/* fprintf(ficgp,"\n replot \"%s\" u 1:(($3-1.96$4)%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
Line 4078 void varevsij(char optionfilefiname[], d	Line 4322 void varevsij(char optionfilefiname[], d
fprintf(ficgp,"\n replot \"%s\" u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));	fprintf(ficgp,"\n replot \"%s\" u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
fprintf(ficgp,"\n replot \"%s\" u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));	fprintf(ficgp,"\n replot \"%s\" u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));	fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);	fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
/* fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);	/* fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
*/	*/
/* fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */	/* fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"varmuptjgr",digitp),digit);	fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);

free_vector(xp,1,npar);	free_vector(xp,1,npar);
free_matrix(doldm,1,nlstate,1,nlstate);	free_matrix(doldm,1,nlstate,1,nlstate);
Line 4097 void varevsij(char optionfilefiname[], d	Line 4341 void varevsij(char optionfilefiname[], d
} /* end varevsij */	} /* end varevsij */

/********** Variance of prevlim ****************/	/********** Variance of prevlim ****************/
void varprevlim(char fileres[], double varpl, double matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double oldm, double savm, double **prlim, double ftolpl, int ij, char strstart[])	void varprevlim(char fileres[], double varpl, double matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double oldm, double savm, double *prlim, double ftolpl, int ncvyearp, int ij, char strstart[])
{	{
/* Variance of prevalence limit */	/* Variance of prevalence limit for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
/* double prevalim(double prlim, int nlstate, double xp, double age, double oldm, double savm,double ftolpl);/	/* double prevalim(double prlim, int nlstate, double xp, double age, double oldm, double savm,double ftolpl);/

double dnewm,doldm;	double dnewm,doldm;
Line 4107 void varprevlim(char fileres[], double *	Line 4351 void varprevlim(char fileres[], double *
double *xp;	double *xp;
double gp, gm;	double gp, gm;
double gradg, trgradg;	double gradg, trgradg;
	double mgm, mgp;
double age,agelim;	double age,agelim;
int theta;	int theta;

Line 4129 void varprevlim(char fileres[], double *	Line 4374 void varprevlim(char fileres[], double *
if (stepm >= YEARM) hstepm=1;	if (stepm >= YEARM) hstepm=1;
nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */	nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
gradg=matrix(1,npar,1,nlstate);	gradg=matrix(1,npar,1,nlstate);
	mgp=matrix(1,npar,1,nlstate);
	mgm=matrix(1,npar,1,nlstate);
gp=vector(1,nlstate);	gp=vector(1,nlstate);
gm=vector(1,nlstate);	gm=vector(1,nlstate);

Line 4136 void varprevlim(char fileres[], double *	Line 4383 void varprevlim(char fileres[], double *
for(i=1; i<=npar; i++){ /* Computes gradient */	for(i=1; i<=npar; i++){ /* Computes gradient */
xp[i] = x[i] + (i==theta ?delti[theta]:0);	xp[i] = x[i] + (i==theta ?delti[theta]:0);
}	}
prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);	if((int)age==79 \|\|(int)age== 80 \|\|(int)age== 81 )
for(i=1;i<=nlstate;i++)	prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
	else
	prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
	for(i=1;i<=nlstate;i++){
gp[i] = prlim[i][i];	gp[i] = prlim[i][i];
	mgp[theta][i] = prlim[i][i];
	}
for(i=1; i<=npar; i++) /* Computes gradient */	for(i=1; i<=npar; i++) /* Computes gradient */
xp[i] = x[i] - (i==theta ?delti[theta]:0);	xp[i] = x[i] - (i==theta ?delti[theta]:0);
prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);	if((int)age==79 \|\|(int)age== 80 \|\|(int)age== 81 )
for(i=1;i<=nlstate;i++)	prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
	else
	prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
	for(i=1;i<=nlstate;i++){
gm[i] = prlim[i][i];	gm[i] = prlim[i][i];
	mgm[theta][i] = prlim[i][i];
	}
for(i=1;i<=nlstate;i++)	for(i=1;i<=nlstate;i++)
gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];	gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
	/* gradg[theta][2]= -gradg[theta][1]; / / For testing if nlstate=2 */
} /* End theta */	} /* End theta */

trgradg =matrix(1,nlstate,1,npar);	trgradg =matrix(1,nlstate,1,npar);
Line 4155 void varprevlim(char fileres[], double *	Line 4411 void varprevlim(char fileres[], double *
for(j=1; j<=nlstate;j++)	for(j=1; j<=nlstate;j++)
for(theta=1; theta <=npar; theta++)	for(theta=1; theta <=npar; theta++)
trgradg[j][theta]=gradg[theta][j];	trgradg[j][theta]=gradg[theta][j];
	/* if((int)age==79 \|\|(int)age== 80 \|\|(int)age== 81 ){ */
	/* printf("\nmgm mgp %d ",(int)age); */
	/* for(j=1; j<=nlstate;j++){ */
	/* printf(" %d ",j); */
	/* for(theta=1; theta <=npar; theta++) */
	/* printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
	/* printf("\n "); */
	/* } */
	/* } */
	/* if((int)age==79 \|\|(int)age== 80 \|\|(int)age== 81 ){ */
	/* printf("\n gradg %d ",(int)age); */
	/* for(j=1; j<=nlstate;j++){ */
	/* printf("%d ",j); */
	/* for(theta=1; theta <=npar; theta++) */
	/* printf("%d %lf ",theta,gradg[theta][j]); */
	/* printf("\n "); */
	/* } */
	/* } */

for(i=1;i<=nlstate;i++)	for(i=1;i<=nlstate;i++)
varpl[i][(int)age] =0.;	varpl[i][(int)age] =0.;
	if((int)age==79 \|\|(int)age== 80 \|\|(int)age== 81){
	matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
	matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
	}else{
matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);	matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);	matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
	}
for(i=1;i<=nlstate;i++)	for(i=1;i<=nlstate;i++)
varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */	varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */

Line 4169 void varprevlim(char fileres[], double *	Line 4448 void varprevlim(char fileres[], double *
fprintf(ficresvpl,"\n");	fprintf(ficresvpl,"\n");
free_vector(gp,1,nlstate);	free_vector(gp,1,nlstate);
free_vector(gm,1,nlstate);	free_vector(gm,1,nlstate);
	free_matrix(mgm,1,npar,1,nlstate);
	free_matrix(mgp,1,npar,1,nlstate);
free_matrix(gradg,1,npar,1,nlstate);	free_matrix(gradg,1,npar,1,nlstate);
free_matrix(trgradg,1,nlstate,1,npar);	free_matrix(trgradg,1,nlstate,1,npar);
} /* End age */	} /* End age */
Line 4200 void varprob(char optionfilefiname[], do	Line 4481 void varprob(char optionfilefiname[], do
char fileresprobcor[FILENAMELENGTH];	char fileresprobcor[FILENAMELENGTH];
double ***varpij;	double ***varpij;

strcpy(fileresprob,"prob");	strcpy(fileresprob,"PROB_");
strcat(fileresprob,fileres);	strcat(fileresprob,fileres);
if((ficresprob=fopen(fileresprob,"w"))==NULL) {	if((ficresprob=fopen(fileresprob,"w"))==NULL) {
printf("Problem with resultfile: %s\n", fileresprob);	printf("Problem with resultfile: %s\n", fileresprob);
fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);	fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
}	}
strcpy(fileresprobcov,"probcov");	strcpy(fileresprobcov,"PROBCOV_");
strcat(fileresprobcov,fileres);	strcat(fileresprobcov,fileresu);
if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {	if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
printf("Problem with resultfile: %s\n", fileresprobcov);	printf("Problem with resultfile: %s\n", fileresprobcov);
fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);	fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
}	}
strcpy(fileresprobcor,"probcor");	strcpy(fileresprobcor,"PROBCOR_");
strcat(fileresprobcor,fileres);	strcat(fileresprobcor,fileresu);
if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {	if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
printf("Problem with resultfile: %s\n", fileresprobcor);	printf("Problem with resultfile: %s\n", fileresprobcor);
fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);	fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
Line 4471 To be simple, these graphs help to under	Line 4752 To be simple, these graphs help to under
fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);	fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
fprintf(ficgp,"\nset ter svg size 640, 480");	fprintf(ficgp,"\nset ter svg size 640, 480");
fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\	fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
:<a href=\"%s%d%1d%1d-%1d%1d.svg\">\	:<a href=\"%s_%d%1d%1d-%1d%1d.svg\">\
%s%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\	%s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2,\	subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,\
subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);	subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
fprintf(fichtmcov,"\n<br><img src=\"%s%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);	fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);	fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
fprintf(ficgp,"\nset out \"%s%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);	fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);	fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);	fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f(%11.3e%11.3ecos(t)+%11.3e%11.3esin(t)), %11.3e +%.3f(%11.3e%11.3ecos(t)+%11.3e%11.3esin(t)) not",\	fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f(%11.3e%11.3ecos(t)+%11.3e%11.3esin(t)), %11.3e +%.3f(%11.3e%11.3ecos(t)+%11.3e%11.3esin(t)) not",\
Line 4494 To be simple, these graphs help to under	Line 4775 To be simple, these graphs help to under
}/* if first */	}/* if first */
} /* age mod 5 */	} /* age mod 5 */
} /* end loop age */	} /* end loop age */
fprintf(ficgp,"\nset out;\nset out \"%s%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"varpijgr"), j1,k1,l1,k2,l2);	fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
first=1;	first=1;
} /l12 /	} /l12 /
} /* k12 */	} /* k12 */
Line 4516 To be simple, these graphs help to under	Line 4797 To be simple, these graphs help to under


/***************** Printing html file *********/	/***************** Printing html file *********/
void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \	void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
int lastpass, int stepm, int weightopt, char model[],\	int lastpass, int stepm, int weightopt, char model[],\
int imx,int jmin, int jmax, double jmeanint,char rfileres[],\	int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
int popforecast, int estepm ,\	int popforecast, int estepm ,\
Line 4529 void printinghtml(char fileres[], char t	Line 4810 void printinghtml(char fileres[], char t
</ul>");	</ul>");
fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n \	fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n \
- Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> <br>\n ",	- Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> <br>\n ",
jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirf2(fileres,"p"),subdirf2(fileres,"p"));	jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",	- Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
stepm,subdirf2(fileres,"pij"),subdirf2(fileres,"pij"));	stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",	- Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
subdirf2(fileres,"pl"),subdirf2(fileres,"pl"));	subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- (a) Life expectancies by health status at initial age, ei. (b) health expectancies by health status at initial age, eij . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \	- (a) Life expectancies by health status at initial age, ei. (b) health expectancies by health status at initial age, eij . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
<a href=\"%s\">%s</a> <br>\n",	<a href=\"%s\">%s</a> <br>\n",
estepm,subdirf2(fileres,"e"),subdirf2(fileres,"e"));	estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- Population projections by age and states: \	- Population projections by age and states: \
<a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileres,"f"),subdirf2(fileres,"f"));	<a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));

fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");	fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");

Line 4561 fprintf(fichtm," \n<ul><li><b>Graphs</b>	Line 4842 fprintf(fichtm," \n<ul><li><b>Graphs</b>
}	}
fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");	fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
}	}
	/* aij, bij */
	fprintf(fichtm,"<br>- Logit model, for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1.svg\">%s_%d-1.svg</a><br> \
	<img src=\"%s_%d-1.svg\">",subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
/* Pij */	/* Pij */
fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s%d_1.svg\">%s%d_1.svg</a><br> \	fprintf(fichtm,"<br>\n- Pij or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2.svg\">%s_%d-2.svg</a><br> \
<img src=\"%s%d_1.svg\">",stepm,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1);	<img src=\"%s_%d-2.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
/* Quasi-incidences */	/* Quasi-incidences */
fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\	fprintf(fichtm,"<br>\n- Iij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too: <a href=\"%s%d_2.svg\">%s%d_2.svg</a><br> \	before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too,\
<img src=\"%s%d_2.svg\">",stepm,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1,subdirf2(optionfilefiname,"pe"),jj1);	incidence (rates) are the limit when h tends to zero of the ratio of the probability hPij \
/* Period (stable) prevalence in each health state */	divided by h: hPij/h : <a href=\"%s_%d-3.svg\">%s_%d-3.svg</a><br> \
for(cpt=1; cpt<=nlstate;cpt++){	<img src=\"%s_%d-3.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
fprintf(fichtm,"<br>- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \	/* Survival functions (period) in state j */
<img src=\"%s%d_%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"p"),cpt,jj1,subdirf2(optionfilefiname,"p"),cpt,jj1,subdirf2(optionfilefiname,"p"),cpt,jj1);	for(cpt=1; cpt<=nlstate;cpt++){
}	fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
	<img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1);
	}
	/* State specific survival functions (period) */
	for(cpt=1; cpt<=nlstate;cpt++){
	fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
	Or probability to survive in various states (1 to %d) being in state %d at different ages.\
	<a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> <img src=\"%s_%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1);
	}
	/* Period (stable) prevalence in each health state */
	for(cpt=1; cpt<=nlstate;cpt++){
	fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
	<img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1);
	}
for(cpt=1; cpt<=nlstate;cpt++) {	for(cpt=1; cpt<=nlstate;cpt++) {
fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) : <a href=\"%s%d%d.svg\">%s%d%d.svg</a> <br> \	fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d%d.svg\">%s_%d%d.svg</a> <br> \
<img src=\"%s%d%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"exp"),cpt,jj1,subdirf2(optionfilefiname,"exp"),cpt,jj1,subdirf2(optionfilefiname,"exp"),cpt,jj1);	<img src=\"%s_%d%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1);
}	}
/* } /\* end i1 \/ /	/* } /\* end i1 \/ /
}/* End k1 */	}/* End k1 */
Line 4584 fprintf(fichtm," \n<ul><li><b>Graphs</b>	Line 4881 fprintf(fichtm," \n<ul><li><b>Graphs</b>
fprintf(fichtm,"\	fprintf(fichtm,"\
\n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\	\n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
- Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \	- Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
- 95%% confidence intervals and Wald tests of the estimated parameters are in the log file.<br> \	- 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
But because parameters are usually highly correlated (a higher incidence of disability \	But because parameters are usually highly correlated (a higher incidence of disability \
and a higher incidence of recovery can give very close observed transition) it might \	and a higher incidence of recovery can give very close observed transition) it might \
be very useful to look not only at linear confidence intervals estimated from the \	be very useful to look not only at linear confidence intervals estimated from the \
Line 4594 covariance matrix of the one-step probab	Line 4891 covariance matrix of the one-step probab
See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);	See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);

fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",	fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
subdirf2(fileres,"prob"),subdirf2(fileres,"prob"));	subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",	- Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
subdirf2(fileres,"probcov"),subdirf2(fileres,"probcov"));	subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));

fprintf(fichtm,"\	fprintf(fichtm,"\
- Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",	- Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
subdirf2(fileres,"probcor"),subdirf2(fileres,"probcor"));	subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \	- Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
<a href=\"%s\">%s</a> <br>\n</li>",	<a href=\"%s\">%s</a> <br>\n</li>",
estepm,subdirf2(fileres,"cve"),subdirf2(fileres,"cve"));	estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \	- (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
<a href=\"%s\">%s</a> <br>\n</li>",	<a href=\"%s\">%s</a> <br>\n</li>",
estepm,subdirf2(fileres,"stde"),subdirf2(fileres,"stde"));	estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",	- Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
estepm, subdirf2(fileres,"v"),subdirf2(fileres,"v"));	estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",	- Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
estepm, subdirf2(fileres,"t"),subdirf2(fileres,"t"));	estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
fprintf(fichtm,"\	fprintf(fichtm,"\
- Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\	- Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
subdirf2(fileres,"vpl"),subdirf2(fileres,"vpl"));	subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));

/* if(popforecast==1) fprintf(fichtm,"\n */	/* if(popforecast==1) fprintf(fichtm,"\n */
/* - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */	/* - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
Line 4644 See page 'Matrix of variance-covariance	Line 4941 See page 'Matrix of variance-covariance
}	}
for(cpt=1; cpt<=nlstate;cpt++) {	for(cpt=1; cpt<=nlstate;cpt++) {
fprintf(fichtm,"<br>- Observed (cross-sectional) and period (incidence based) \	fprintf(fichtm,"<br>- Observed (cross-sectional) and period (incidence based) \
prevalence (with 95%% confidence interval) in state (%d): %s%d_%d.svg <br>\	prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d%d.svg\"> %s_%d-%d.svg <br>\
<img src=\"%s%d_%d.svg\">",cpt,subdirf2(optionfilefiname,"v"),cpt,jj1,subdirf2(optionfilefiname,"v"),cpt,jj1);	<img src=\"%s_%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1);
}	}
fprintf(fichtm,"\n<br>- Total life expectancy by age and \	fprintf(fichtm,"\n<br>- Total life expectancy by age and \
health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \	health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
true period expectancies (those weighted with period prevalences are also\	true period expectancies (those weighted with period prevalences are also\
drawn in addition to the population based expectancies computed using\	drawn in addition to the population based expectancies computed using\
observed and cahotic prevalences: %s%d.svg<br>\	observed and cahotic prevalences: <a href=\"%s_%d.svg\">%s_%d.svg<br>\
<img src=\"%s%d.svg\">",subdirf2(optionfilefiname,"e"),jj1,subdirf2(optionfilefiname,"e"),jj1);	<img src=\"%s_%d.svg\">",subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1);
/* } /\* end i1 \/ /	/* } /\* end i1 \/ /
}/* End k1 */	}/* End k1 */
fprintf(fichtm,"</ul>");	fprintf(fichtm,"</ul>");
Line 4660 true period expectancies (those weighted	Line 4957 true period expectancies (those weighted
}	}

/***************** Gnuplot file ************/	/***************** Gnuplot file ************/
void printinggnuplot(char fileres[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){	void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){

char dirfileres[132],optfileres[132];	char dirfileres[132],optfileres[132];
int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0;	int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0;
int ng=0;	int ng=0;
	int vpopbased;
/* if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */	/* if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
/* printf("Problem with file %s",optionfilegnuplot); */	/* printf("Problem with file %s",optionfilegnuplot); */
/* fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */	/* fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
Line 4675 void printinggnuplot(char fileres[], cha	Line 4973 void printinggnuplot(char fileres[], cha
/#endif /	/#endif /
m=pow(2,cptcoveff);	m=pow(2,cptcoveff);

	/* Contribution to likelihood */
	/* Plot the probability implied in the likelihood */
	fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
	fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
	/* fprintf(ficgp,"\nset ter svg size 640, 480"); / / Too big for svg */
	fprintf(ficgp,"\nset ter pngcairo size 640, 480");
	/* nice for mle=4 plot by number of matrix products.
	replot "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
	/* replot exp(p1+p2x)/(1+exp(p1+p2x)+exp(p3+p4x)+exp(p5+p6x)) t "p12(x)" */
	/* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
	fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
	fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$12):5 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
	fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
	fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$12):4 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
	for (i=1; i<= nlstate ; i ++) {
	fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
	fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot \"%s\"",subdirf(fileresilk));
	fprintf(ficgp," u 2:($4 == %d && $5==%d ? $9 : 1/0):($11/4.):5 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
	for (j=2; j<= nlstate+ndeath ; j ++) {
	fprintf(ficgp,",\\\n \"\" u 2:($4 == %d && $5==%d ? $9 : 1/0):($11/4.):5 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
	}
	fprintf(ficgp,";\nset out; unset ylabel;\n");
	}
	/* unset log; plot "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */
	/* fprintf(ficgp,"\nset log y;plot \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
	/* fprintf(ficgp,"\nreplot \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
	fprintf(ficgp,"\nset out;unset log\n");
	/* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */

strcpy(dirfileres,optionfilefiname);	strcpy(dirfileres,optionfilefiname);
strcpy(optfileres,"vpl");	strcpy(optfileres,"vpl");
/* 1eme*/	/* 1eme*/
fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'vpl' files\n");	fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files\n");
for (cpt=1; cpt<= nlstate ; cpt ++) {	for (cpt=1; cpt<= nlstate ; cpt ++) {
for (k1=1; k1<= m ; k1 ++) { /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */	for (k1=1; k1<= m ; k1 ++) { /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
fprintf(ficgp,"\nset out \"%s%d_%d.svg\" \n",subdirf2(optionfilefiname,"v"),cpt,k1);	fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1);
fprintf(ficgp,"\n#set out \"v%s%d_%d.svg\" \n",optionfilefiname,cpt,k1);	fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1);
fprintf(ficgp,"set xlabel \"Age\" \n\	fprintf(ficgp,"set xlabel \"Age\" \n\
set ylabel \"Probability\" \n\	set ylabel \"Probability\" \n\
set ter svg size 640, 480\n\	set ter svg size 640, 480\n\
plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileres,"vpl"),k1-1,k1-1);	plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1);

for (i=1; i<= nlstate ; i ++) {	for (i=1; i<= nlstate ; i ++) {
if (i==cpt) fprintf(ficgp," %%lf (%%lf)");	if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
else fprintf(ficgp," %%lf (%%lf)");	else fprintf(ficgp," %%lf (%%lf)");
}	}
fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileres,"vpl"),k1-1,k1-1);	fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1);
for (i=1; i<= nlstate ; i ++) {	for (i=1; i<= nlstate ; i ++) {
if (i==cpt) fprintf(ficgp," %%lf (%%lf)");	if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
else fprintf(ficgp," %%lf (%%lf)");	else fprintf(ficgp," %%lf (%%lf)");
}	}
fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileres,"vpl"),k1-1,k1-1);	fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1);
for (i=1; i<= nlstate ; i ++) {	for (i=1; i<= nlstate ; i ++) {
if (i==cpt) fprintf(ficgp," %%lf (%%lf)");	if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
else fprintf(ficgp," %%lf (%%lf)");	else fprintf(ficgp," %%lf (%%lf)");
}	}
fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l lt 2",subdirf2(fileres,"p"),k1-1,k1-1,2+4*(cpt-1));	fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
}	fprintf(ficgp,"\nset out \n");
}	} /* k1 */
	} /* cpt */
/2 eme/	/2 eme/
fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files\n");	fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files\n");
for (k1=1; k1<= m ; k1 ++) {	for (k1=1; k1<= m ; k1 ++) {
fprintf(ficgp,"\nset out \"%s%d.svg\" \n",subdirf2(optionfilefiname,"e"),k1);	fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1);
fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);	for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
	if(vpopbased==0)
for (i=1; i<= nlstate+1 ; i ++) {	fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
k=2*i;	else
fprintf(ficgp,"\"%s\" every :::%d::%d u 1:2 \"%%lf",subdirf2(fileres,"t"),k1-1,k1-1);	fprintf(ficgp,"\nreplot ");
for (j=1; j<= nlstate+1 ; j ++) {	for (i=1; i<= nlstate+1 ; i ++) {
if (j==i) fprintf(ficgp," %%lf (%%lf)");	k=2*i;
else fprintf(ficgp," %%lf (%%lf)");	fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
}	for (j=1; j<= nlstate+1 ; j ++) {
if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");	if (j==i) fprintf(ficgp," %%lf (%%lf)");
else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);	else fprintf(ficgp," %%lf (%%lf)");
fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2-$3*2) \"%%lf",subdirf2(fileres,"t"),k1-1,k1-1);	}
for (j=1; j<= nlstate+1 ; j ++) {	if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
if (j==i) fprintf(ficgp," %%lf (%%lf)");	else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
else fprintf(ficgp," %%lf (%%lf)");	fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
}	for (j=1; j<= nlstate+1 ; j ++) {
fprintf(ficgp,"\" t\"\" w l lt 0,");	if (j==i) fprintf(ficgp," %%lf (%%lf)");
fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2+$3*2) \"%%lf",subdirf2(fileres,"t"),k1-1,k1-1);	else fprintf(ficgp," %%lf (%%lf)");
for (j=1; j<= nlstate+1 ; j ++) {	}
if (j==i) fprintf(ficgp," %%lf (%%lf)");	fprintf(ficgp,"\" t\"\" w l lt 0,");
else fprintf(ficgp," %%lf (%%lf)");	fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
}	for (j=1; j<= nlstate+1 ; j ++) {
if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");	if (j==i) fprintf(ficgp," %%lf (%%lf)");
else fprintf(ficgp,"\" t\"\" w l lt 0,");	else fprintf(ficgp," %%lf (%%lf)");
}	}
}	if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
	else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
	} /* state */
	} /* vpopbased */
	fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */
	} /* k1 */
/3eme/	/3eme/

for (k1=1; k1<= m ; k1 ++) {	for (k1=1; k1<= m ; k1 ++) {
for (cpt=1; cpt<= nlstate ; cpt ++) {	for (cpt=1; cpt<= nlstate ; cpt ++) {
/* k=2+nlstate(2cpt-2); */	/* k=2+nlstate(2cpt-2); */
k=2+(nlstate+1)*(cpt-1);	k=2+(nlstate+1)*(cpt-1);
fprintf(ficgp,"\nset out \"%s%d%d.svg\" \n",subdirf2(optionfilefiname,"exp"),cpt,k1);	fprintf(ficgp,"\nset out \"%s_%d%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1);
fprintf(ficgp,"set ter svg size 640, 480\n\	fprintf(ficgp,"set ter svg size 640, 480\n\
plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileres,"e"),k1-1,k1-1,k,cpt);	plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
/fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);	/fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");	for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
fprintf(ficgp,"\" t \"e%d1\" w l",cpt);	fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
Line 4754 plot [%.f:%.f] \"%s\" every :::%d::%d u	Line 5086 plot [%.f:%.f] \"%s\" every :::%d::%d u

*/	*/
for (i=1; i< nlstate ; i ++) {	for (i=1; i< nlstate ; i ++) {
fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+i,cpt,i+1);	fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
/* fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2i,cpt,i+1);/	/* fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2i,cpt,i+1);/

}	}
fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+nlstate,cpt);	fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
}	}
}	}

/* CV preval stable (period) */	/* Survival functions (period) from state i in state j by initial state i */
for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */	for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */	for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
k=3;	k=3;
	fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'lij' files, cov=%d state=%d",k1, cpt);
	fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1);
	fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
	set ter svg size 640, 480\n\
	unset log y\n\
	plot [%.f:%.f] ", ageminpar, agemaxpar);
	for (i=1; i<= nlstate ; i ++){
	if(i==1)
	fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
	else
	fprintf(ficgp,", '' ");
	l=(nlstate+ndeath)*(i-1)+1;
	fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
	for (j=2; j<= nlstate+ndeath ; j ++)
	fprintf(ficgp,"+$%d",k+l+j-1);
	fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
	} /* nlstate */
	fprintf(ficgp,"\nset out\n");
	} /* end cpt state*/
	} /* end covariate */

	/* Survival functions (period) from state i in state j by final state j */
	for (k1=1; k1<= m ; k1 ++) { /* For each covariate if any */
	for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state */
	k=3;
	fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
	fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1);
	fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
	set ter svg size 640, 480\n\
	unset log y\n\
	plot [%.f:%.f] ", ageminpar, agemaxpar);
	for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
	if(j==1)
	fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
	else
	fprintf(ficgp,", '' ");
	l=(nlstate+ndeath)*(cpt-1) +j;
	fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
	/* for (i=2; i<= nlstate+ndeath ; i ++) */
	/* fprintf(ficgp,"+$%d",k+l+i-1); */
	fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
	} /* nlstate */
	fprintf(ficgp,", '' ");
	fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
	for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
	l=(nlstate+ndeath)*(cpt-1) +j;
	if(j < nlstate)
	fprintf(ficgp,"$%d +",k+l);
	else
	fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
	}
	fprintf(ficgp,"\nset out\n");
	} /* end cpt state*/
	} /* end covariate */

	/* CV preval stable (period) for each covariate */
	for (k1=1; k1<= m ; k1 ++) { /* For each covariate if any */
	for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
	k=3;
fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, cov=%d state=%d",k1, cpt);	fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, cov=%d state=%d",k1, cpt);
fprintf(ficgp,"\nset out \"%s%d_%d.svg\" \n",subdirf2(optionfilefiname,"p"),cpt,k1);	fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1);
fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\	fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
set ter svg size 640, 480\n\	set ter svg size 640, 480\n\
unset log y\n\	unset log y\n\
plot [%.f:%.f] ", ageminpar, agemaxpar);	plot [%.f:%.f] ", ageminpar, agemaxpar);
for (i=1; i<= nlstate ; i ++){	for (i=1; i<= nlstate ; i ++){
if(i==1)	if(i==1)
fprintf(ficgp,"\"%s\"",subdirf2(fileres,"pij"));	fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
else	else
fprintf(ficgp,", '' ");	fprintf(ficgp,", '' ");
l=(nlstate+ndeath)*(i-1)+1;	l=(nlstate+ndeath)*(i-1)+1;
fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);	fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
for (j=1; j<= (nlstate-1) ; j ++)	for (j=2; j<= nlstate ; j ++)
fprintf(ficgp,"+$%d",k+l+j);	fprintf(ficgp,"+$%d",k+l+j-1);
fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);	fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
} /* nlstate */	} /* nlstate */
fprintf(ficgp,"\n");	fprintf(ficgp,"\nset out\n");
} /* end cpt state*/	} /* end cpt state*/
} /* end covariate */	} /* end covariate */

/* proba elementaires */	/* proba elementaires */
fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n");	fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n");
for(i=1,jk=1; i <=nlstate; i++){	for(i=1,jk=1; i <=nlstate; i++){
Line 4819 plot [%.f:%.f] ", ageminpar, agemaxpar)	Line 5210 plot [%.f:%.f] ", ageminpar, agemaxpar)
fprintf(ficgp,"# +exp(a13+b13age+c13ageage+d13V1+e13V1*age))\n");	fprintf(ficgp,"# +exp(a13+b13age+c13ageage+d13V1+e13V1*age))\n");
fprintf(ficgp,"# +exp(a14+b14age+c14ageage+d14V1+e14V1*age)+...)\n");	fprintf(ficgp,"# +exp(a14+b14age+c14ageage+d14V1+e14V1*age)+...)\n");
fprintf(ficgp,"#\n");	fprintf(ficgp,"#\n");
for(ng=1; ng<=2;ng++){ /* Number of graphics: first is probabilities second is incidence per year*/	for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
fprintf(ficgp,"# ng=%d\n",ng);	fprintf(ficgp,"# ng=%d\n",ng);
fprintf(ficgp,"# jk=1 to 2^%d=%d\n",cptcoveff,m);	fprintf(ficgp,"# jk=1 to 2^%d=%d\n",cptcoveff,m);
for(jk=1; jk <=m; jk++) {	for(jk=1; jk <=m; jk++) {
fprintf(ficgp,"# jk=%d\n",jk);	fprintf(ficgp,"# jk=%d\n",jk);
fprintf(ficgp,"\nset out \"%s%d_%d.svg\" \n",subdirf2(optionfilefiname,"pe"),jk,ng);	fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng);
if (ng==2)	fprintf(ficgp,"\nset ter svg size 640, 480 ");
	if (ng==1){
	fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12x) could be nice /
	fprintf(ficgp,"\nunset log y");
	}else if (ng==2){
	fprintf(ficgp,"\nset ylabel \"Probability\"\n");
	fprintf(ficgp,"\nset log y");
	}else if (ng==3){
fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");	fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
else	fprintf(ficgp,"\nset log y");
fprintf(ficgp,"\nunset title \n");	}else
fprintf(ficgp,"\nset ter svg size 640, 480\nset log y\nplot [%.f:%.f] ",ageminpar,agemaxpar);	fprintf(ficgp,"\nunset title ");
	fprintf(ficgp,"\nplot [%.f:%.f] ",ageminpar,agemaxpar);
i=1;	i=1;
for(k2=1; k2<=nlstate; k2++) {	for(k2=1; k2<=nlstate; k2++) {
k3=i;	k3=i;
for(k=1; k<=(nlstate+ndeath); k++) {	for(k=1; k<=(nlstate+ndeath); k++) {
if (k != k2){	if (k != k2){
if(ng==2)	switch( ng) {
	case 1:
if(nagesqr==0)	if(nagesqr==0)
fprintf(ficgp," %fexp(p%d+p%dx",YEARM/stepm,i,i+1);	fprintf(ficgp," p%d+p%d*x",i,i+1);
else /* nagesqr =1 */	else /* nagesqr =1 */
fprintf(ficgp," %fexp(p%d+p%dx+p%dxx",YEARM/stepm,i,i+1,i+1+nagesqr);	fprintf(ficgp," p%d+p%dx+p%dx*x",i,i+1,i+1+nagesqr);
else	break;
	case 2: /* ng=2 */
if(nagesqr==0)	if(nagesqr==0)
fprintf(ficgp," exp(p%d+p%d*x",i,i+1);	fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
else /* nagesqr =1 */	else /* nagesqr =1 */
fprintf(ficgp," exp(p%d+p%dx+p%dx*x",i,i+1,i+1+nagesqr);	fprintf(ficgp," exp(p%d+p%dx+p%dx*x",i,i+1,i+1+nagesqr);
	break;
	case 3:
	if(nagesqr==0)
	fprintf(ficgp," %fexp(p%d+p%dx",YEARM/stepm,i,i+1);
	else /* nagesqr =1 */
	fprintf(ficgp," %fexp(p%d+p%dx+p%dxx",YEARM/stepm,i,i+1,i+1+nagesqr);
	break;
	}
ij=1;/* To be checked else nbcode[0][0] wrong */	ij=1;/* To be checked else nbcode[0][0] wrong */
for(j=3; j <=ncovmodel-nagesqr; j++) {	for(j=3; j <=ncovmodel-nagesqr; j++) {
/* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */	/* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
Line 4858 plot [%.f:%.f] ", ageminpar, agemaxpar)	Line 5267 plot [%.f:%.f] ", ageminpar, agemaxpar)
else	else
fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);	fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
}	}
fprintf(ficgp,")/(1");	if(ng != 1){
	fprintf(ficgp,")/(1");

for(k1=1; k1 <=nlstate; k1++){	for(k1=1; k1 <=nlstate; k1++){
if(nagesqr==0)	if(nagesqr==0)
fprintf(ficgp,"+exp(p%d+p%dx",k3+(k1-1)ncovmodel,k3+(k1-1)*ncovmodel+1);	fprintf(ficgp,"+exp(p%d+p%dx",k3+(k1-1)ncovmodel,k3+(k1-1)*ncovmodel+1);
else /* nagesqr =1 */	else /* nagesqr =1 */
fprintf(ficgp,"+exp(p%d+p%dx+p%dxx",k3+(k1-1)ncovmodel,k3+(k1-1)ncovmodel+1,k3+(k1-1)ncovmodel+1+nagesqr);	fprintf(ficgp,"+exp(p%d+p%dx+p%dxx",k3+(k1-1)ncovmodel,k3+(k1-1)ncovmodel+1,k3+(k1-1)ncovmodel+1+nagesqr);

ij=1;	ij=1;
for(j=3; j <=ncovmodel-nagesqr; j++){	for(j=3; j <=ncovmodel-nagesqr; j++){
if(ij <=cptcovage) { /* Bug valgrind */	if(ij <=cptcovage) { /* Bug valgrind */
if((j-2)==Tage[ij]) { /* Bug valgrind */	if((j-2)==Tage[ij]) { /* Bug valgrind */
fprintf(ficgp,"+p%d%dx",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);	fprintf(ficgp,"+p%d%dx",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
/* fprintf(ficgp,"+p%d%dx",k3+(k1-1)ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); /	/* fprintf(ficgp,"+p%d%dx",k3+(k1-1)ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); /
ij++;	ij++;
	}
}	}
	else
	fprintf(ficgp,"+p%d%d",k3+(k1-1)ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
}	}
else	fprintf(ficgp,")");
fprintf(ficgp,"+p%d%d",k3+(k1-1)ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
}	}
fprintf(ficgp,")");	fprintf(ficgp,")");
	if(ng ==2)
	fprintf(ficgp," t \"p%d%d\" ", k2,k);
	else /* ng= 3 */
	fprintf(ficgp," t \"i%d%d\" ", k2,k);
	}else{ /* end ng <> 1 */
	fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
}	}
fprintf(ficgp,") t \"p%d%d\" ", k2,k);
if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");	if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");
i=i+ncovmodel;	i=i+ncovmodel;
}	}
} /* end k */	} /* end k */
} /* end k2 */	} /* end k2 */
	fprintf(ficgp,"\n set out\n");
} /* end jk */	} /* end jk */
} /* end ng */	} /* end ng */
/* avoid: */	/* avoid: */
Line 4953 void prevforecast(char fileres[], double	Line 5371 void prevforecast(char fileres[], double
agelim=AGESUP;	agelim=AGESUP;
prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);	prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);

strcpy(fileresf,"f");	strcpy(fileresf,"F_");
strcat(fileresf,fileres);	strcat(fileresf,fileresu);
if((ficresf=fopen(fileresf,"w"))==NULL) {	if((ficresf=fopen(fileresf,"w"))==NULL) {
printf("Problem with forecast resultfile: %s\n", fileresf);	printf("Problem with forecast resultfile: %s\n", fileresf);
fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);	fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
Line 5077 void populforecast(char fileres[], doubl	Line 5495 void populforecast(char fileres[], doubl
prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);	prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);


strcpy(filerespop,"pop");	strcpy(filerespop,"POP_");
strcat(filerespop,fileres);	strcat(filerespop,fileresu);
if((ficrespop=fopen(filerespop,"w"))==NULL) {	if((ficrespop=fopen(filerespop,"w"))==NULL) {
printf("Problem with forecast resultfile: %s\n", filerespop);	printf("Problem with forecast resultfile: %s\n", filerespop);
fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);	fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);
Line 5431 double gompertz_f(const gsl_vector *v, v	Line 5849 double gompertz_f(const gsl_vector *v, v
#endif	#endif

/***************** Printing html file *********/	/***************** Printing html file *********/
void printinghtmlmort(char fileres[], char title[], char datafile[], int firstpass, \	void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
int lastpass, int stepm, int weightopt, char model[],\	int lastpass, int stepm, int weightopt, char model[],\
int imx, double p[],double **matcov,double agemortsup){	int imx, double p[],double **matcov,double agemortsup){
int i,k;	int i,k;
Line 5455 fprintf(fichtm,"<ul><li><h4>Life table</	Line 5873 fprintf(fichtm,"<ul><li><h4>Life table</
}	}

/***************** Gnuplot file ************/	/***************** Gnuplot file ************/
void printinggnuplotmort(char fileres[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){	void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){

char dirfileres[132],optfileres[132];	char dirfileres[132],optfileres[132];

Line 6162 void syscompilerinfo(int logged)	Line 6580 void syscompilerinfo(int logged)

}	}

int prevalence_limit(double p, double *prlim, double ageminpar, double agemaxpar){	int prevalence_limit(double p, double prlim, double ageminpar, double agemaxpar, double ftolpl, int ncvyearp){
/--------------- Prevalence limit (period or stable prevalence) --------------/	/--------------- Prevalence limit (period or stable prevalence) --------------/
int i, j, k, i1 ;	int i, j, k, i1 ;
double ftolpl = 1.e-10;	/* double ftolpl = 1.e-10; */
double age, agebase, agelim;	double age, agebase, agelim;
	double tot;

strcpy(filerespl,"pl");	strcpy(filerespl,"PL_");
strcat(filerespl,fileres);	strcat(filerespl,fileresu);
if((ficrespl=fopen(filerespl,"w"))==NULL) {	if((ficrespl=fopen(filerespl,"w"))==NULL) {
printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;	printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;	fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
}	}
printf("Computing period (stable) prevalence: result on file '%s' \n", filerespl);	printf("Computing period (stable) prevalence: result on file '%s' \n", filerespl);
fprintf(ficlog,"Computing period (stable) prevalence: result on file '%s' \n", filerespl);	fprintf(ficlog,"Computing period (stable) prevalence: result on file '%s' \n", filerespl);
pstamp(ficrespl);	pstamp(ficrespl);
fprintf(ficrespl,"# Period (stable) prevalence \n");	fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
fprintf(ficrespl,"#Age ");	fprintf(ficrespl,"#Age ");
for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);	for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
fprintf(ficrespl,"\n");	fprintf(ficrespl,"\n");

/* prlim=matrix(1,nlstate,1,nlstate);/ / back in main */	/* prlim=matrix(1,nlstate,1,nlstate);/ / back in main */

Line 6212 int prevalence_limit(double p, double	Line 6631 int prevalence_limit(double p, double
for(j=1;j<=cptcoveff;j++) {	for(j=1;j<=cptcoveff;j++) {
fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);	fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
}	}
for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);	for(i=1; i<=nlstate;i++) fprintf(ficrespl," %d-%d ",i,i);
fprintf(ficrespl,"\n");	fprintf(ficrespl,"Total Years_to_converge\n");

for (age=agebase; age<=agelim; age++){	for (age=agebase; age<=agelim; age++){
/* for (age=agebase; age<=agebase; age++){ */	/* for (age=agebase; age<=agebase; age++){ */
prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);	prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k);
fprintf(ficrespl,"%.0f ",age );	fprintf(ficrespl,"%.0f ",age );
for(j=1;j<=cptcoveff;j++)	for(j=1;j<=cptcoveff;j++)
fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);	fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
for(i=1; i<=nlstate;i++)	tot=0.;
	for(i=1; i<=nlstate;i++){
	tot += prlim[i][i];
fprintf(ficrespl," %.5f", prlim[i][i]);	fprintf(ficrespl," %.5f", prlim[i][i]);
fprintf(ficrespl,"\n");	}
	fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
} /* Age */	} /* Age */
/* was end of cptcod */	/* was end of cptcod */
} /* cptcov */	} /* cptcov */
Line 6242 int hPijx(double *p, int bage, int fage)	Line 6664 int hPijx(double *p, int bage, int fage)
double agedeb;	double agedeb;
double ***p3mat;	double ***p3mat;

strcpy(filerespij,"pij"); strcat(filerespij,fileres);	strcpy(filerespij,"PIJ_"); strcat(filerespij,fileresu);
if((ficrespij=fopen(filerespij,"w"))==NULL) {	if((ficrespij=fopen(filerespij,"w"))==NULL) {
printf("Problem with Pij resultfile: %s\n", filerespij); return 1;	printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;	fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
Line 6316 int main(int argc, char *argv[])	Line 6738 int main(int argc, char *argv[])
#endif	#endif
int movingaverage(double *probs, double bage,double fage, double *mobaverage, int mobilav);	int movingaverage(double *probs, double bage,double fage, double *mobaverage, int mobilav);
int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;	int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
	int ncvyear=0; /* Number of years needed for the period prevalence to converge */
int jj, ll, li, lj, lk;	int jj, ll, li, lj, lk;
int numlinepar=0; /* Current linenumber of parameter file */	int numlinepar=0; /* Current linenumber of parameter file */
int num_filled;	int num_filled;
Line 6364 int main(int argc, char *argv[])	Line 6786 int main(int argc, char *argv[])
double **param; / Matrix of parameters */	double **param; / Matrix of parameters */
double *p;	double *p;
double *matcov; / Matrix of covariance */	double *matcov; / Matrix of covariance */
	double *hess; / Hessian matrix */
double **delti3; / Scale */	double **delti3; / Scale */
double delti; / Scale */	double delti; / Scale */
double *eij, *vareij;	double *eij, *vareij;
Line 6423 int main(int argc, char *argv[])	Line 6846 int main(int argc, char *argv[])
printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);	printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
if(argc <=1){	if(argc <=1){
printf("\nEnter the parameter file name: ");	printf("\nEnter the parameter file name: ");
fgets(pathr,FILENAMELENGTH,stdin);	if(!fgets(pathr,FILENAMELENGTH,stdin)){
	printf("ERROR Empty parameter file name\n");
	goto end;
	}
i=strlen(pathr);	i=strlen(pathr);
if(pathr[i-1]=='\n')	if(pathr[i-1]=='\n')
pathr[i-1]='\0';	pathr[i-1]='\0';
i=strlen(pathr);	i=strlen(pathr);
if(pathr[i-1]==' ') /* This may happen when dragging on oS/X! */	if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
pathr[i-1]='\0';	pathr[i-1]='\0';
for (tok = pathr; tok != NULL; ){	}
	i=strlen(pathr);
	if( i==0 ){
	printf("ERROR Empty parameter file name\n");
	goto end;
	}
	for (tok = pathr; tok != NULL; ){
printf("Pathr \|%s\|\n",pathr);	printf("Pathr \|%s\|\n",pathr);
while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');	while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
printf("val= \|%s\| pathr=%s\n",val,pathr);	printf("val= \|%s\| pathr=%s\n",val,pathr);
Line 6503 int main(int argc, char *argv[])	Line 6935 int main(int argc, char *argv[])
/* */	/* */
strcpy(fileres,"r");	strcpy(fileres,"r");
strcat(fileres, optionfilefiname);	strcat(fileres, optionfilefiname);
	strcat(fileresu, optionfilefiname); /* Without r in front */
strcat(fileres,".txt"); /* Other files have txt extension */	strcat(fileres,".txt"); /* Other files have txt extension */
	strcat(fileresu,".txt"); /* Other files have txt extension */

/* Main ---------arguments file --------*/	/* Main ---------arguments file --------*/

Line 6518 int main(int argc, char *argv[])	Line 6952 int main(int argc, char *argv[])


strcpy(filereso,"o");	strcpy(filereso,"o");
strcat(filereso,fileres);	strcat(filereso,fileresu);
if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */	if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
printf("Problem with Output resultfile: %s\n", filereso);	printf("Problem with Output resultfile: %s\n", filereso);
fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);	fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
Line 6564 int main(int argc, char *argv[])	Line 6998 int main(int argc, char *argv[])
if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \	if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
&ftol, &stepm, &ncovcol, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){	&ftol, &stepm, &ncovcol, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
if (num_filled != 8) {	if (num_filled != 8) {
printf("Not 8\n");	printf("Not 8 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
	printf("but line=%s\n",line);
}	}
printf("ftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt);	printf("ftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt);
}	}
	/* ftolpl=6ftol1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit \/ /
	/ftolpl=6.e-4; //* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
/* Third parameter line */	/* Third parameter line */
while(fgets(line, MAXLINE, ficpar)) {	while(fgets(line, MAXLINE, ficpar)) {
/* If line starts with a # it is a comment */	/* If line starts with a # it is a comment */
Line 6581 int main(int argc, char *argv[])	Line 7017 int main(int argc, char *argv[])
}else	}else
break;	break;
}	}
if((num_filled=sscanf(line,"model=1+age%[^.\n]\n", model)) !=EOF){	if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
if (num_filled != 1) {	if (num_filled == 0)
	model[0]='\0';
	else if (num_filled != 1){
printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);	printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);	fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
model[0]='\0';	model[0]='\0';
Line 6592 int main(int argc, char *argv[])	Line 7030 int main(int argc, char *argv[])
if (model[0]=='+'){	if (model[0]=='+'){
for(i=1; i<=strlen(model);i++)	for(i=1; i<=strlen(model);i++)
modeltemp[i-1]=model[i];	modeltemp[i-1]=model[i];
	strcpy(model,modeltemp);
}	}
strcpy(model,modeltemp);
}	}
/* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */	/* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
	printf("model=1+age+%s\n",model);fflush(stdout);
}	}
/* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */	/* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
/* numlinepar=numlinepar+3; /\* In general \/ /	/* numlinepar=numlinepar+3; /\* In general \/ /
/* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */	/* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
if(model[strlen(model)-1]=='.') /* Suppressing leading dot in the model */	fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
model[strlen(model)-1]='\0';	fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
fflush(ficlog);	fflush(ficlog);
/* if(model[0]=='#'\|\| model[0]== '\0'){ */	/* if(model[0]=='#'\|\| model[0]== '\0'){ */
if(model[0]=='#'){	if(model[0]=='#'){
Line 6668 int main(int argc, char *argv[])	Line 7105 int main(int argc, char *argv[])
fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);	fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);	param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
matcov=matrix(1,npar,1,npar);	matcov=matrix(1,npar,1,npar);
	hess=matrix(1,npar,1,npar);
}	}
else{	else{
/* Read guessed parameters */	/* Read guessed parameters */
Line 6776 run imach with mle=-1 to get a correct t	Line 7214 run imach with mle=-1 to get a correct t
ungetc(c,ficpar);	ungetc(c,ficpar);

matcov=matrix(1,npar,1,npar);	matcov=matrix(1,npar,1,npar);
	hess=matrix(1,npar,1,npar);
for(i=1; i <=npar; i++)	for(i=1; i <=npar; i++)
for(j=1; j <=npar; j++) matcov[i][j]=0.;	for(j=1; j <=npar; j++) matcov[i][j]=0.;

Line 6827 Please run with mle=-1 to get a correct	Line 7266 Please run with mle=-1 to get a correct
strcat(rfileres,"."); /* */	strcat(rfileres,"."); /* */
strcat(rfileres,optionfilext); /* Other files have txt extension */	strcat(rfileres,optionfilext); /* Other files have txt extension */
if((ficres =fopen(rfileres,"w"))==NULL) {	if((ficres =fopen(rfileres,"w"))==NULL) {
printf("Problem writing new parameter file: %s\n", fileres);goto end;	printf("Problem writing new parameter file: %s\n", rfileres);goto end;
fprintf(ficlog,"Problem writing new parameter file: %s\n", fileres);goto end;	fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
}	}
fprintf(ficres,"#%s\n",version);	fprintf(ficres,"#%s\n",version);
} /* End of mle != -3 */	} /* End of mle != -3 */
Line 6971 Please run with mle=-1 to get a correct	Line 7410 Please run with mle=-1 to get a correct
* 15 i=8 1 2 2 2	* 15 i=8 1 2 2 2
* 16 2 2 2 2	* 16 2 2 2 2
*/	*/
for(h=1; h <=100 ;h++){	/* /\* for(h=1; h <=100 ;h++){ \/ /
/* printf("h=%2d ", h); */	/* /\* printf("h=%2d ", h); \/ /
/* for(k=1; k <=10; k++){ */	/* /\* for(k=1; k <=10; k++){ \/ /
/* printf("k=%d %d ",k,codtabm(h,k)); */	/* /\* printf("k=%d %d ",k,codtabm(h,k)); \/ /
/* codtab[h][k]=codtabm(h,k); */	/* /\* codtab[h][k]=codtabm(h,k); \/ /
/* } */	/* /\* } \/ /
/* printf("\n"); */	/* /\* printf("\n"); \/ /
}	/* } */
/* for(k=1;k<=cptcoveff; k++){ /\* scans any effective covariate \/ /	/* for(k=1;k<=cptcoveff; k++){ /\* scans any effective covariate \/ /
/* for(i=1; i <=pow(2,cptcoveff-k);i++){ /\* i=1 to 8/1=8; i=1 to 8/2=4; i=1 to 8/8=1 \/ /	/* for(i=1; i <=pow(2,cptcoveff-k);i++){ /\* i=1 to 8/1=8; i=1 to 8/2=4; i=1 to 8/8=1 \/ /
/* for(j=1; j <= ncodemax[k]; j++){ /\* For each modality of this covariate ncodemax=2\/ /	/* for(j=1; j <= ncodemax[k]; j++){ /\* For each modality of this covariate ncodemax=2\/ /
Line 7011 Please run with mle=-1 to get a correct	Line 7450 Please run with mle=-1 to get a correct
/* Initialisation of ----------- gnuplot -------------*/	/* Initialisation of ----------- gnuplot -------------*/
strcpy(optionfilegnuplot,optionfilefiname);	strcpy(optionfilegnuplot,optionfilefiname);
if(mle==-3)	if(mle==-3)
strcat(optionfilegnuplot,"-mort");	strcat(optionfilegnuplot,"-MORT_");
strcat(optionfilegnuplot,".gp");	strcat(optionfilegnuplot,".gp");

if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {	if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
printf("Problem with file %s",optionfilegnuplot);	printf("Problem with file %s",optionfilegnuplot);
}	}
else{	else{
fprintf(ficgp,"\n# %s\n", version);	fprintf(ficgp,"\n# IMaCh-%s\n", version);
fprintf(ficgp,"# %s\n", optionfilegnuplot);	fprintf(ficgp,"# %s\n", optionfilegnuplot);
//fprintf(ficgp,"set missing 'NaNq'\n");	//fprintf(ficgp,"set missing 'NaNq'\n");
fprintf(ficgp,"set datafile missing 'NaNq'\n");	fprintf(ficgp,"set datafile missing 'NaNq'\n");
Line 7030 Please run with mle=-1 to get a correct	Line 7469 Please run with mle=-1 to get a correct

strcpy(optionfilehtm,optionfilefiname); /* Main html file */	strcpy(optionfilehtm,optionfilefiname); /* Main html file */
if(mle==-3)	if(mle==-3)
strcat(optionfilehtm,"-mort");	strcat(optionfilehtm,"-MORT_");
strcat(optionfilehtm,".htm");	strcat(optionfilehtm,".htm");
if((fichtm=fopen(optionfilehtm,"w"))==NULL) {	if((fichtm=fopen(optionfilehtm,"w"))==NULL) {
printf("Problem with %s \n",optionfilehtm);	printf("Problem with %s \n",optionfilehtm);
Line 7045 Please run with mle=-1 to get a correct	Line 7484 Please run with mle=-1 to get a correct
else{	else{
fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \	fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
<hr size=\"2\" color=\"#EC5E5E\"> \n\	<hr size=\"2\" color=\"#EC5E5E\"> \n\
Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n",\	Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);	optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
}	}

fprintf(fichtm,"<html><head>\n<title>IMaCh %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \	fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C) 2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015</a></font><br> \
	<hr size=\"2\" color=\"#EC5E5E\"> \n\
	<font size=\"2\">IMaCh-%s <br> %s</font> \
<hr size=\"2\" color=\"#EC5E5E\"> \n\	<hr size=\"2\" color=\"#EC5E5E\"> \n\
Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n\	Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
\n\	\n\
<hr size=\"2\" color=\"#EC5E5E\">\	<hr size=\"2\" color=\"#EC5E5E\">\
<ul><li><h4>Parameter files</h4>\n\	<ul><li><h4>Parameter files</h4>\n\
Line 7146 Interval (in months) between two waves:	Line 7587 Interval (in months) between two waves:
#else	#else
printf("Powell\n"); fprintf(ficlog,"Powell\n");	printf("Powell\n"); fprintf(ficlog,"Powell\n");
#endif	#endif
strcpy(filerespow,"pow-mort");	strcpy(filerespow,"POW-MORT_");
strcat(filerespow,fileres);	strcat(filerespow,fileresu);
if((ficrespow=fopen(filerespow,"w"))==NULL) {	if((ficrespow=fopen(filerespow,"w"))==NULL) {
printf("Problem with resultfile: %s\n", filerespow);	printf("Problem with resultfile: %s\n", filerespow);
fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);	fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
Line 7243 Interval (in months) between two waves:	Line 7684 Interval (in months) between two waves:
#endif	#endif
fclose(ficrespow);	fclose(ficrespow);

hesscov(matcov, p, NDIM, delti, 1e-4, gompertz);	hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz);

for(i=1; i <=NDIM; i++)	for(i=1; i <=NDIM; i++)
for(j=i+1;j<=NDIM;j++)	for(j=i+1;j<=NDIM;j++)
matcov[i][j]=matcov[j][i];	matcov[i][j]=matcov[j][i];

printf("\nCovariance matrix\n ");	printf("\nCovariance matrix\n ");
	fprintf(ficlog,"\nCovariance matrix\n ");
for(i=1; i <=NDIM; i++) {	for(i=1; i <=NDIM; i++) {
for(j=1;j<=NDIM;j++){	for(j=1;j<=NDIM;j++){
printf("%f ",matcov[i][j]);	printf("%f ",matcov[i][j]);
	fprintf(ficlog,"%f ",matcov[i][j]);
}	}
printf("\n ");	printf("\n "); fprintf(ficlog,"\n ");
}	}

printf("iter=%d MLE=%f Eq=%lfexp(%lf(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);	printf("iter=%d MLE=%f Eq=%lfexp(%lf(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
Line 7301 Please run with mle=-1 to get a correct	Line 7744 Please run with mle=-1 to get a correct
This is probably because your parameter file doesn't \n contain the exact number of lines (or columns) corresponding to your model line.\n\	This is probably because your parameter file doesn't \n contain the exact number of lines (or columns) corresponding to your model line.\n\
Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);	Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
}else	}else
printinggnuplotmort(fileres, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);	printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
printinghtmlmort(fileres,title,datafile, firstpass, lastpass, \	printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
stepm, weightopt,\	stepm, weightopt,\
model,imx,p,matcov,agemortsup);	model,imx,p,matcov,agemortsup);

Line 7316 Please run with mle=-1 to get a correct	Line 7759 Please run with mle=-1 to get a correct
free_matrix(ximort,1,NDIM,1,NDIM);	free_matrix(ximort,1,NDIM,1,NDIM);
#endif	#endif
} /* Endof if mle==-3 mortality only */	} /* Endof if mle==-3 mortality only */
/* Standard maximisation */	/* Standard */
else{ /* For mle >=1 */	else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
globpr=0;/* debug */	globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
/* Computes likelihood for initial parameters */	/* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */	likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);	printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
for (k=1; k<=npar;k++)	for (k=1; k<=npar;k++)
printf(" %d %8.5f",k,p[k]);	printf(" %d %8.5f",k,p[k]);
printf("\n");	printf("\n");
globpr=1; /* again, to print the contributions */	if(mle>=1){ /* Could be 1 or 2, Real Maximization */
	/* mlikeli uses func not funcone */
	mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
	}
	if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
	globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
	/* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
	likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
	}
	globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */	likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);	printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
for (k=1; k<=npar;k++)	for (k=1; k<=npar;k++)
printf(" %d %8.5f",k,p[k]);	printf(" %d %8.5f",k,p[k]);
printf("\n");	printf("\n");
if(mle>=1){ /* Could be 1 or 2, Real Maximisation */
mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
}

/--------- results files --------------/	/--------- results files --------------/
fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);	fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);
Line 7360 Please run with mle=-1 to get a correct	Line 7809 Please run with mle=-1 to get a correct
}	}
}	}
}	}
if(mle!=0){	if(mle != 0){
/* Computing hessian and covariance matrix */	/* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
ftolhess=ftol; /* Usually correct */	ftolhess=ftol; /* Usually correct */
hesscov(matcov, p, npar, delti, ftolhess, func);	hesscov(matcov, hess, p, npar, delti, ftolhess, func);
}	printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");	fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");	for(i=1,jk=1; i <=nlstate; i++){
for(i=1,jk=1; i <=nlstate; i++){	for(k=1; k <=(nlstate+ndeath); k++){
for(k=1; k <=(nlstate+ndeath); k++){	if (k != i) {
if (k != i) {	printf("%d%d ",i,k);
printf("%d%d ",i,k);	fprintf(ficlog,"%d%d ",i,k);
fprintf(ficlog,"%d%d ",i,k);	for(j=1; j <=ncovmodel; j++){
for(j=1; j <=ncovmodel; j++){	printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96sqrt(matcov[jk][jk]),p[jk]+1.96sqrt(matcov[jk][jk]));
printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96sqrt(matcov[jk][jk]),p[jk]+1.96sqrt(matcov[jk][jk]));	fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96sqrt(matcov[jk][jk]),p[jk]+1.96sqrt(matcov[jk][jk]));
fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96sqrt(matcov[jk][jk]),p[jk]+1.96sqrt(matcov[jk][jk]));	jk++;
jk++;	}
	printf("\n");
	fprintf(ficlog,"\n");
}	}
printf("\n");
fprintf(ficlog,"\n");
}	}
}	}
}	} /* end of hesscov and Wald tests */

	/* */
fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");	fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
printf("# Scales (for hessian or gradient estimation)\n");	printf("# Scales (for hessian or gradient estimation)\n");
fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");	fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
Line 7406 Please run with mle=-1 to get a correct	Line 7856 Please run with mle=-1 to get a correct
}	}

fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n# ...\n# 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n");	fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n# ...\n# 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n");
if(mle>=1)	if(mle >= 1) /* To big for the screen */
printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n# ...\n# 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n");	printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n# ...\n# 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n");
fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n# ...\n# 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n");	fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n# ...\n# 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n");
/* # 121 Var(a12)\n\ */	/* # 121 Var(a12)\n\ */
Line 7469 Please run with mle=-1 to get a correct	Line 7919 Please run with mle=-1 to get a correct
fprintf(ficres," Var(%s%1d%1d)",ca,i,j);	fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
}else{	}else{
if(mle>=1)	if(mle>=1)
printf(" %.5e",matcov[jj][ll]);	printf(" %.7e",matcov[jj][ll]);
fprintf(ficlog," %.5e",matcov[jj][ll]);	fprintf(ficlog," %.7e",matcov[jj][ll]);
fprintf(ficres," %.5e",matcov[jj][ll]);	fprintf(ficres," %.7e",matcov[jj][ll]);
}	}
}	}
}	}
Line 7490 Please run with mle=-1 to get a correct	Line 7940 Please run with mle=-1 to get a correct

fflush(ficlog);	fflush(ficlog);
fflush(ficres);	fflush(ficres);
	while(fgets(line, MAXLINE, ficpar)) {
while((c=getc(ficpar))=='#' && c!= EOF){	/* If line starts with a # it is a comment */
ungetc(c,ficpar);	if (line[0] == '#') {
fgets(line, MAXLINE, ficpar);	numlinepar++;
fputs(line,stdout);	fputs(line,stdout);
fputs(line,ficparo);	fputs(line,ficparo);
}	fputs(line,ficlog);
ungetc(c,ficpar);	continue;
	}else
	break;
	}

	/* while((c=getc(ficpar))=='#' && c!= EOF){ */
	/* ungetc(c,ficpar); */
	/* fgets(line, MAXLINE, ficpar); */
	/* fputs(line,stdout); */
	/* fputs(line,ficparo); */
	/* } */
	/* ungetc(c,ficpar); */

estepm=0;	estepm=0;
fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);	if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){

	if (num_filled != 6) {
	printf("Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n");
	printf("but line=%s\n",line);
	goto end;
	}
	printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
	}
	/* ftolpl=6ftol1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit \/ /
	/ftolpl=6.e-4;/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */

	/* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
if (estepm==0 \|\| estepm < stepm) estepm=stepm;	if (estepm==0 \|\| estepm < stepm) estepm=stepm;
if (fage <= 2) {	if (fage <= 2) {
bage = ageminpar;	bage = ageminpar;
Line 7572 Please run with mle=-1 to get a correct	Line 8045 Please run with mle=-1 to get a correct
This is probably because your parameter file doesn't \n contain the exact number of lines (or columns) corresponding to your model line.\n\	This is probably because your parameter file doesn't \n contain the exact number of lines (or columns) corresponding to your model line.\n\
Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);	Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
}else	}else
printinggnuplot(fileres, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);	printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);

printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,\	printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt,\
model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,\	model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,\
jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);	jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);

Line 7599 Please run with mle=-1 to get a correct	Line 8072 Please run with mle=-1 to get a correct
/--------------- Prevalence limit (period or stable prevalence) --------------/	/--------------- Prevalence limit (period or stable prevalence) --------------/
/#include "prevlim.h"/ /* Use ficrespl, ficlog */	/#include "prevlim.h"/ /* Use ficrespl, ficlog */
prlim=matrix(1,nlstate,1,nlstate);	prlim=matrix(1,nlstate,1,nlstate);
prevalence_limit(p, prlim, ageminpar, agemaxpar);	prevalence_limit(p, prlim, ageminpar, agemaxpar, ftolpl, &ncvyear);
fclose(ficrespl);	fclose(ficrespl);

#ifdef FREEEXIT2	#ifdef FREEEXIT2
Line 7626 Please run with mle=-1 to get a correct	Line 8099 Please run with mle=-1 to get a correct
/if((stepm == 1) && (strcmp(model,".")==0)){/	/if((stepm == 1) && (strcmp(model,".")==0)){/
if(prevfcast==1){	if(prevfcast==1){
/* if(stepm ==1){*/	/* if(stepm ==1){*/
prevforecast(fileres, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);	prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
/* (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);*/	/* (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);*/
/* } */	/* } */
/* else{ */	/* else{ */
Line 7656 Please run with mle=-1 to get a correct	Line 8129 Please run with mle=-1 to get a correct

/---------- Health expectancies, no variances ------------/	/---------- Health expectancies, no variances ------------/

strcpy(filerese,"e");	strcpy(filerese,"E_");
strcat(filerese,fileres);	strcat(filerese,fileresu);
if((ficreseij=fopen(filerese,"w"))==NULL) {	if((ficreseij=fopen(filerese,"w"))==NULL) {
printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);	printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);	fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
}	}
printf("Computing Health Expectancies: result on file '%s' \n", filerese);	printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
fprintf(ficlog,"Computing Health Expectancies: result on file '%s' \n", filerese);	fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
/*for(cptcov=1,k=0;cptcov<=i1;cptcov++){	/*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/	for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/

Line 7682 Please run with mle=-1 to get a correct	Line 8155 Please run with mle=-1 to get a correct
/}/	/}/
}	}
fclose(ficreseij);	fclose(ficreseij);
	printf("done evsij\n");fflush(stdout);
	fprintf(ficlog,"done evsij\n");fflush(ficlog);

/---------- Health expectancies and variances ------------/	/---------- Health expectancies and variances ------------/


strcpy(filerest,"t");	strcpy(filerest,"T_");
strcat(filerest,fileres);	strcat(filerest,fileresu);
if((ficrest=fopen(filerest,"w"))==NULL) {	if((ficrest=fopen(filerest,"w"))==NULL) {
printf("Problem with total LE resultfile: %s\n", filerest);goto end;	printf("Problem with total LE resultfile: %s\n", filerest);goto end;
fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;	fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
}	}
printf("Computing Total Life expectancies with their standard errors: file '%s' \n", filerest);	printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' \n", filerest);	fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);


strcpy(fileresstde,"stde");	strcpy(fileresstde,"STDE_");
strcat(fileresstde,fileres);	strcat(fileresstde,fileresu);
if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {	if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
printf("Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);	printf("Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
fprintf(ficlog,"Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);	fprintf(ficlog,"Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
}	}
printf("Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);	printf(" Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
fprintf(ficlog,"Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);	fprintf(ficlog," Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);

strcpy(filerescve,"cve");	strcpy(filerescve,"CVE_");
strcat(filerescve,fileres);	strcat(filerescve,fileresu);
if((ficrescveij=fopen(filerescve,"w"))==NULL) {	if((ficrescveij=fopen(filerescve,"w"))==NULL) {
printf("Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);	printf("Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
fprintf(ficlog,"Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);	fprintf(ficlog,"Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
}	}
printf("Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);	printf(" Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
fprintf(ficlog,"Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);	fprintf(ficlog," Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);

strcpy(fileresv,"v");	strcpy(fileresv,"V_");
strcat(fileresv,fileres);	strcat(fileresv,fileresu);
if((ficresvij=fopen(fileresv,"w"))==NULL) {	if((ficresvij=fopen(fileresv,"w"))==NULL) {
printf("Problem with variance resultfile: %s\n", fileresv);exit(0);	printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);	fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
}	}
printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);	printf(" Computing Variance-covariance of DFLEs: file '%s' ... ", fileresv);fflush(stdout);
fprintf(ficlog,"Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);	fprintf(ficlog," Computing Variance-covariance of DFLEs: file '%s' ... ", fileresv);fflush(ficlog);

/*for(cptcov=1,k=0;cptcov<=i1;cptcov++){	/*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/	for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/

for (k=1; k <= (int) pow(2,cptcoveff); k++){	for (k=1; k <= (int) pow(2,cptcoveff); k++){
fprintf(ficrest,"\n#****** ");	fprintf(ficrest,"\n#****** ");
for(j=1;j<=cptcoveff;j++)	for(j=1;j<=cptcoveff;j++)
fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);	fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
fprintf(ficrest,"******\n");	fprintf(ficrest,"******\n");

fprintf(ficresstdeij,"\n#****** ");	fprintf(ficresstdeij,"\n#****** ");
fprintf(ficrescveij,"\n#****** ");	fprintf(ficrescveij,"\n#****** ");
for(j=1;j<=cptcoveff;j++) {	for(j=1;j<=cptcoveff;j++) {
fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);	fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);	fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
}	}
fprintf(ficresstdeij,"******\n");	fprintf(ficresstdeij,"******\n");
fprintf(ficrescveij,"******\n");	fprintf(ficrescveij,"******\n");

fprintf(ficresvij,"\n#****** ");	fprintf(ficresvij,"\n#****** ");
for(j=1;j<=cptcoveff;j++)	for(j=1;j<=cptcoveff;j++)
fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);	fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
fprintf(ficresvij,"******\n");	fprintf(ficresvij,"******\n");

eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);	eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
oldm=oldms;savm=savms;	oldm=oldms;savm=savms;
cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);	printf(" cvevsij %d, ",k);
/*	fprintf(ficlog, " cvevsij %d, ",k);
*/	cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);
/* goto endfree; */	printf(" end cvevsij \n ");
	fprintf(ficlog, " end cvevsij \n ");
vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
pstamp(ficrest);	/*
	*/
	/* goto endfree; */
for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
oldm=oldms;savm=savms; /* ZZ Segmentation fault */	vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
cptcod= 0; /* To be deleted */	pstamp(ficrest);
varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart); /* cptcod not initialized Intel */
fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n# (weighted average of eij where weights are ");
if(vpopbased==1)	for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);	oldm=oldms;savm=savms; /* ZZ Segmentation fault */
else	cptcod= 0; /* To be deleted */
fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");	printf("varevsij %d \n",vpopbased);
fprintf(ficrest,"# Age e.. (std) ");	fprintf(ficlog, "varevsij %d \n",vpopbased);
for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);	varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart); /* cptcod not initialized Intel */
fprintf(ficrest,"\n");	fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n# (weighted average of eij where weights are ");
/* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */	if(vpopbased==1)
epj=vector(1,nlstate+1);	fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
for(age=bage; age <=fage ;age++){	else
prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k); /ZZ Is it the correct prevalim /	fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
if (vpopbased==1) {	fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
if(mobilav ==0){	for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
for(i=1; i<=nlstate;i++)	fprintf(ficrest,"\n");
prlim[i][i]=probs[(int)age][i][k];	/* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
}else{ /* mobilav */	epj=vector(1,nlstate+1);
for(i=1; i<=nlstate;i++)	printf("Computing age specific period (stable) prevalences in each health state \n");
prlim[i][i]=mobaverage[(int)age][i][k];	fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
}	for(age=bage; age <=fage ;age++){
}	prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k); /ZZ Is it the correct prevalim /
	if (vpopbased==1) {
fprintf(ficrest," %4.0f",age);	if(mobilav ==0){
/* printf(" age %4.0f ",age); */	for(i=1; i<=nlstate;i++)
for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){	prlim[i][i]=probs[(int)age][i][k];
for(i=1, epj[j]=0.;i <=nlstate;i++) {	}else{ /* mobilav */
epj[j] += prlim[i][i]*eij[i][j][(int)age];	for(i=1; i<=nlstate;i++)
/ZZZ printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);/	prlim[i][i]=mobaverage[(int)age][i][k];
/* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
}
epj[nlstate+1] +=epj[j];
}	}
/* printf(" age %4.0f \n",age); */	}

for(i=1, vepp=0.;i <=nlstate;i++)	fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
for(j=1;j <=nlstate;j++)	/* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); / / to be done */
vepp += vareij[i][j][(int)age];	/* printf(" age %4.0f ",age); */
fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));	for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
for(j=1;j <=nlstate;j++){	for(i=1, epj[j]=0.;i <=nlstate;i++) {
fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));	epj[j] += prlim[i][i]*eij[i][j][(int)age];
	/ZZZ printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);/
	/* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
}	}
fprintf(ficrest,"\n");	epj[nlstate+1] +=epj[j];
	}
	/* printf(" age %4.0f \n",age); */

	for(i=1, vepp=0.;i <=nlstate;i++)
	for(j=1;j <=nlstate;j++)
	vepp += vareij[i][j][(int)age];
	fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
	for(j=1;j <=nlstate;j++){
	fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
}	}
	fprintf(ficrest,"\n");
}	}
free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);	} /* End vpopbased */
free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);	free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
free_vector(epj,1,nlstate+1);	free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
	free_vector(epj,1,nlstate+1);
	printf("done \n");fflush(stdout);
	fprintf(ficlog,"done\n");fflush(ficlog);

/}/	/}/
}	} /* End k */
free_vector(weight,1,n);	free_vector(weight,1,n);
free_imatrix(Tvard,1,NCOVMAX,1,2);	free_imatrix(Tvard,1,NCOVMAX,1,2);
free_imatrix(s,1,maxwav+1,1,n);	free_imatrix(s,1,maxwav+1,1,n);
Line 7822 Please run with mle=-1 to get a correct	Line 8309 Please run with mle=-1 to get a correct
fclose(ficrescveij);	fclose(ficrescveij);
fclose(ficresvij);	fclose(ficresvij);
fclose(ficrest);	fclose(ficrest);
	printf("done Health expectancies\n");fflush(stdout);
	fprintf(ficlog,"done Health expectancies\n");fflush(ficlog);
fclose(ficpar);	fclose(ficpar);

/------- Variance of period (stable) prevalence------/	/------- Variance of period (stable) prevalence------/

strcpy(fileresvpl,"vpl");	strcpy(fileresvpl,"VPL_");
strcat(fileresvpl,fileres);	strcat(fileresvpl,fileresu);
if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {	if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
printf("Problem with variance of period (stable) prevalence resultfile: %s\n", fileresvpl);	printf("Problem with variance of period (stable) prevalence resultfile: %s\n", fileresvpl);
exit(0);	exit(0);
}	}
printf("Computing Variance-covariance of period (stable) prevalence: file '%s' \n", fileresvpl);	printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
	fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);

/*for(cptcov=1,k=0;cptcov<=i1;cptcov++){	/*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/	for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
Line 7845 Please run with mle=-1 to get a correct	Line 8335 Please run with mle=-1 to get a correct

varpl=matrix(1,nlstate,(int) bage, (int) fage);	varpl=matrix(1,nlstate,(int) bage, (int) fage);
oldm=oldms;savm=savms;	oldm=oldms;savm=savms;
varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k,strstart);	varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart);
free_matrix(varpl,1,nlstate,(int) bage, (int)fage);	free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
/}/	/}/
}	}

fclose(ficresvpl);	fclose(ficresvpl);
	printf("done variance-covariance of period prevalence\n");fflush(stdout);
	fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);

/---------- End : free ----------------/	/---------- End : free ----------------/
if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);	if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
Line 7864 Please run with mle=-1 to get a correct	Line 8356 Please run with mle=-1 to get a correct
free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);	free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
free_matrix(covar,0,NCOVMAX,1,n);	free_matrix(covar,0,NCOVMAX,1,n);
free_matrix(matcov,1,npar,1,npar);	free_matrix(matcov,1,npar,1,npar);
	free_matrix(hess,1,npar,1,npar);
/free_vector(delti,1,npar);/	/free_vector(delti,1,npar);/
free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);	free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
free_matrix(agev,1,maxwav,1,imx);	free_matrix(agev,1,maxwav,1,imx);

FreeBSD-CVSweb <freebsd-cvsweb@FreeBSD.org>

Removed from v.1.200
changed lines
	Added in v.1.209