Annotation of imach/src/imach.c, revision 1.235

1.235   ! brouard     1: /* $Id: imach.c,v 1.234 2016/08/23 16:51:20 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.235   ! brouard     4:   Revision 1.234  2016/08/23 16:51:20  brouard
        !             5:   *** empty log message ***
        !             6: 
1.234     brouard     7:   Revision 1.233  2016/08/23 07:40:50  brouard
                      8:   Summary: not working
                      9: 
1.233     brouard    10:   Revision 1.232  2016/08/22 14:20:21  brouard
                     11:   Summary: not working
                     12: 
1.232     brouard    13:   Revision 1.231  2016/08/22 07:17:15  brouard
                     14:   Summary: not working
                     15: 
1.231     brouard    16:   Revision 1.230  2016/08/22 06:55:53  brouard
                     17:   Summary: Not working
                     18: 
1.230     brouard    19:   Revision 1.229  2016/07/23 09:45:53  brouard
                     20:   Summary: Completing for func too
                     21: 
1.229     brouard    22:   Revision 1.228  2016/07/22 17:45:30  brouard
                     23:   Summary: Fixing some arrays, still debugging
                     24: 
1.227     brouard    25:   Revision 1.226  2016/07/12 18:42:34  brouard
                     26:   Summary: temp
                     27: 
1.226     brouard    28:   Revision 1.225  2016/07/12 08:40:03  brouard
                     29:   Summary: saving but not running
                     30: 
1.225     brouard    31:   Revision 1.224  2016/07/01 13:16:01  brouard
                     32:   Summary: Fixes
                     33: 
1.224     brouard    34:   Revision 1.223  2016/02/19 09:23:35  brouard
                     35:   Summary: temporary
                     36: 
1.223     brouard    37:   Revision 1.222  2016/02/17 08:14:50  brouard
                     38:   Summary: Probably last 0.98 stable version 0.98r6
                     39: 
1.222     brouard    40:   Revision 1.221  2016/02/15 23:35:36  brouard
                     41:   Summary: minor bug
                     42: 
1.220     brouard    43:   Revision 1.219  2016/02/15 00:48:12  brouard
                     44:   *** empty log message ***
                     45: 
1.219     brouard    46:   Revision 1.218  2016/02/12 11:29:23  brouard
                     47:   Summary: 0.99 Back projections
                     48: 
1.218     brouard    49:   Revision 1.217  2015/12/23 17:18:31  brouard
                     50:   Summary: Experimental backcast
                     51: 
1.217     brouard    52:   Revision 1.216  2015/12/18 17:32:11  brouard
                     53:   Summary: 0.98r4 Warning and status=-2
                     54: 
                     55:   Version 0.98r4 is now:
                     56:    - displaying an error when status is -1, date of interview unknown and date of death known;
                     57:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                     58:   Older changes concerning s=-2, dating from 2005 have been supersed.
                     59: 
1.216     brouard    60:   Revision 1.215  2015/12/16 08:52:24  brouard
                     61:   Summary: 0.98r4 working
                     62: 
1.215     brouard    63:   Revision 1.214  2015/12/16 06:57:54  brouard
                     64:   Summary: temporary not working
                     65: 
1.214     brouard    66:   Revision 1.213  2015/12/11 18:22:17  brouard
                     67:   Summary: 0.98r4
                     68: 
1.213     brouard    69:   Revision 1.212  2015/11/21 12:47:24  brouard
                     70:   Summary: minor typo
                     71: 
1.212     brouard    72:   Revision 1.211  2015/11/21 12:41:11  brouard
                     73:   Summary: 0.98r3 with some graph of projected cross-sectional
                     74: 
                     75:   Author: Nicolas Brouard
                     76: 
1.211     brouard    77:   Revision 1.210  2015/11/18 17:41:20  brouard
                     78:   Summary: Start working on projected prevalences
                     79: 
1.210     brouard    80:   Revision 1.209  2015/11/17 22:12:03  brouard
                     81:   Summary: Adding ftolpl parameter
                     82:   Author: N Brouard
                     83: 
                     84:   We had difficulties to get smoothed confidence intervals. It was due
                     85:   to the period prevalence which wasn't computed accurately. The inner
                     86:   parameter ftolpl is now an outer parameter of the .imach parameter
                     87:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                     88:   computation are long.
                     89: 
1.209     brouard    90:   Revision 1.208  2015/11/17 14:31:57  brouard
                     91:   Summary: temporary
                     92: 
1.208     brouard    93:   Revision 1.207  2015/10/27 17:36:57  brouard
                     94:   *** empty log message ***
                     95: 
1.207     brouard    96:   Revision 1.206  2015/10/24 07:14:11  brouard
                     97:   *** empty log message ***
                     98: 
1.206     brouard    99:   Revision 1.205  2015/10/23 15:50:53  brouard
                    100:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    101: 
1.205     brouard   102:   Revision 1.204  2015/10/01 16:20:26  brouard
                    103:   Summary: Some new graphs of contribution to likelihood
                    104: 
1.204     brouard   105:   Revision 1.203  2015/09/30 17:45:14  brouard
                    106:   Summary: looking at better estimation of the hessian
                    107: 
                    108:   Also a better criteria for convergence to the period prevalence And
                    109:   therefore adding the number of years needed to converge. (The
                    110:   prevalence in any alive state shold sum to one
                    111: 
1.203     brouard   112:   Revision 1.202  2015/09/22 19:45:16  brouard
                    113:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    114: 
1.202     brouard   115:   Revision 1.201  2015/09/15 17:34:58  brouard
                    116:   Summary: 0.98r0
                    117: 
                    118:   - Some new graphs like suvival functions
                    119:   - Some bugs fixed like model=1+age+V2.
                    120: 
1.201     brouard   121:   Revision 1.200  2015/09/09 16:53:55  brouard
                    122:   Summary: Big bug thanks to Flavia
                    123: 
                    124:   Even model=1+age+V2. did not work anymore
                    125: 
1.200     brouard   126:   Revision 1.199  2015/09/07 14:09:23  brouard
                    127:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    128: 
1.199     brouard   129:   Revision 1.198  2015/09/03 07:14:39  brouard
                    130:   Summary: 0.98q5 Flavia
                    131: 
1.198     brouard   132:   Revision 1.197  2015/09/01 18:24:39  brouard
                    133:   *** empty log message ***
                    134: 
1.197     brouard   135:   Revision 1.196  2015/08/18 23:17:52  brouard
                    136:   Summary: 0.98q5
                    137: 
1.196     brouard   138:   Revision 1.195  2015/08/18 16:28:39  brouard
                    139:   Summary: Adding a hack for testing purpose
                    140: 
                    141:   After reading the title, ftol and model lines, if the comment line has
                    142:   a q, starting with #q, the answer at the end of the run is quit. It
                    143:   permits to run test files in batch with ctest. The former workaround was
                    144:   $ echo q | imach foo.imach
                    145: 
1.195     brouard   146:   Revision 1.194  2015/08/18 13:32:00  brouard
                    147:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    148: 
1.194     brouard   149:   Revision 1.193  2015/08/04 07:17:42  brouard
                    150:   Summary: 0.98q4
                    151: 
1.193     brouard   152:   Revision 1.192  2015/07/16 16:49:02  brouard
                    153:   Summary: Fixing some outputs
                    154: 
1.192     brouard   155:   Revision 1.191  2015/07/14 10:00:33  brouard
                    156:   Summary: Some fixes
                    157: 
1.191     brouard   158:   Revision 1.190  2015/05/05 08:51:13  brouard
                    159:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    160: 
                    161:   Fix 1+age+.
                    162: 
1.190     brouard   163:   Revision 1.189  2015/04/30 14:45:16  brouard
                    164:   Summary: 0.98q2
                    165: 
1.189     brouard   166:   Revision 1.188  2015/04/30 08:27:53  brouard
                    167:   *** empty log message ***
                    168: 
1.188     brouard   169:   Revision 1.187  2015/04/29 09:11:15  brouard
                    170:   *** empty log message ***
                    171: 
1.187     brouard   172:   Revision 1.186  2015/04/23 12:01:52  brouard
                    173:   Summary: V1*age is working now, version 0.98q1
                    174: 
                    175:   Some codes had been disabled in order to simplify and Vn*age was
                    176:   working in the optimization phase, ie, giving correct MLE parameters,
                    177:   but, as usual, outputs were not correct and program core dumped.
                    178: 
1.186     brouard   179:   Revision 1.185  2015/03/11 13:26:42  brouard
                    180:   Summary: Inclusion of compile and links command line for Intel Compiler
                    181: 
1.185     brouard   182:   Revision 1.184  2015/03/11 11:52:39  brouard
                    183:   Summary: Back from Windows 8. Intel Compiler
                    184: 
1.184     brouard   185:   Revision 1.183  2015/03/10 20:34:32  brouard
                    186:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    187: 
                    188:   We use directest instead of original Powell test; probably no
                    189:   incidence on the results, but better justifications;
                    190:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    191:   wrong results.
                    192: 
1.183     brouard   193:   Revision 1.182  2015/02/12 08:19:57  brouard
                    194:   Summary: Trying to keep directest which seems simpler and more general
                    195:   Author: Nicolas Brouard
                    196: 
1.182     brouard   197:   Revision 1.181  2015/02/11 23:22:24  brouard
                    198:   Summary: Comments on Powell added
                    199: 
                    200:   Author:
                    201: 
1.181     brouard   202:   Revision 1.180  2015/02/11 17:33:45  brouard
                    203:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    204: 
1.180     brouard   205:   Revision 1.179  2015/01/04 09:57:06  brouard
                    206:   Summary: back to OS/X
                    207: 
1.179     brouard   208:   Revision 1.178  2015/01/04 09:35:48  brouard
                    209:   *** empty log message ***
                    210: 
1.178     brouard   211:   Revision 1.177  2015/01/03 18:40:56  brouard
                    212:   Summary: Still testing ilc32 on OSX
                    213: 
1.177     brouard   214:   Revision 1.176  2015/01/03 16:45:04  brouard
                    215:   *** empty log message ***
                    216: 
1.176     brouard   217:   Revision 1.175  2015/01/03 16:33:42  brouard
                    218:   *** empty log message ***
                    219: 
1.175     brouard   220:   Revision 1.174  2015/01/03 16:15:49  brouard
                    221:   Summary: Still in cross-compilation
                    222: 
1.174     brouard   223:   Revision 1.173  2015/01/03 12:06:26  brouard
                    224:   Summary: trying to detect cross-compilation
                    225: 
1.173     brouard   226:   Revision 1.172  2014/12/27 12:07:47  brouard
                    227:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    228: 
1.172     brouard   229:   Revision 1.171  2014/12/23 13:26:59  brouard
                    230:   Summary: Back from Visual C
                    231: 
                    232:   Still problem with utsname.h on Windows
                    233: 
1.171     brouard   234:   Revision 1.170  2014/12/23 11:17:12  brouard
                    235:   Summary: Cleaning some \%% back to %%
                    236: 
                    237:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    238: 
1.170     brouard   239:   Revision 1.169  2014/12/22 23:08:31  brouard
                    240:   Summary: 0.98p
                    241: 
                    242:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    243: 
1.169     brouard   244:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   245:   Summary: update
1.169     brouard   246: 
1.168     brouard   247:   Revision 1.167  2014/12/22 13:50:56  brouard
                    248:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    249: 
                    250:   Testing on Linux 64
                    251: 
1.167     brouard   252:   Revision 1.166  2014/12/22 11:40:47  brouard
                    253:   *** empty log message ***
                    254: 
1.166     brouard   255:   Revision 1.165  2014/12/16 11:20:36  brouard
                    256:   Summary: After compiling on Visual C
                    257: 
                    258:   * imach.c (Module): Merging 1.61 to 1.162
                    259: 
1.165     brouard   260:   Revision 1.164  2014/12/16 10:52:11  brouard
                    261:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    262: 
                    263:   * imach.c (Module): Merging 1.61 to 1.162
                    264: 
1.164     brouard   265:   Revision 1.163  2014/12/16 10:30:11  brouard
                    266:   * imach.c (Module): Merging 1.61 to 1.162
                    267: 
1.163     brouard   268:   Revision 1.162  2014/09/25 11:43:39  brouard
                    269:   Summary: temporary backup 0.99!
                    270: 
1.162     brouard   271:   Revision 1.1  2014/09/16 11:06:58  brouard
                    272:   Summary: With some code (wrong) for nlopt
                    273: 
                    274:   Author:
                    275: 
                    276:   Revision 1.161  2014/09/15 20:41:41  brouard
                    277:   Summary: Problem with macro SQR on Intel compiler
                    278: 
1.161     brouard   279:   Revision 1.160  2014/09/02 09:24:05  brouard
                    280:   *** empty log message ***
                    281: 
1.160     brouard   282:   Revision 1.159  2014/09/01 10:34:10  brouard
                    283:   Summary: WIN32
                    284:   Author: Brouard
                    285: 
1.159     brouard   286:   Revision 1.158  2014/08/27 17:11:51  brouard
                    287:   *** empty log message ***
                    288: 
1.158     brouard   289:   Revision 1.157  2014/08/27 16:26:55  brouard
                    290:   Summary: Preparing windows Visual studio version
                    291:   Author: Brouard
                    292: 
                    293:   In order to compile on Visual studio, time.h is now correct and time_t
                    294:   and tm struct should be used. difftime should be used but sometimes I
                    295:   just make the differences in raw time format (time(&now).
                    296:   Trying to suppress #ifdef LINUX
                    297:   Add xdg-open for __linux in order to open default browser.
                    298: 
1.157     brouard   299:   Revision 1.156  2014/08/25 20:10:10  brouard
                    300:   *** empty log message ***
                    301: 
1.156     brouard   302:   Revision 1.155  2014/08/25 18:32:34  brouard
                    303:   Summary: New compile, minor changes
                    304:   Author: Brouard
                    305: 
1.155     brouard   306:   Revision 1.154  2014/06/20 17:32:08  brouard
                    307:   Summary: Outputs now all graphs of convergence to period prevalence
                    308: 
1.154     brouard   309:   Revision 1.153  2014/06/20 16:45:46  brouard
                    310:   Summary: If 3 live state, convergence to period prevalence on same graph
                    311:   Author: Brouard
                    312: 
1.153     brouard   313:   Revision 1.152  2014/06/18 17:54:09  brouard
                    314:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    315: 
1.152     brouard   316:   Revision 1.151  2014/06/18 16:43:30  brouard
                    317:   *** empty log message ***
                    318: 
1.151     brouard   319:   Revision 1.150  2014/06/18 16:42:35  brouard
                    320:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    321:   Author: brouard
                    322: 
1.150     brouard   323:   Revision 1.149  2014/06/18 15:51:14  brouard
                    324:   Summary: Some fixes in parameter files errors
                    325:   Author: Nicolas Brouard
                    326: 
1.149     brouard   327:   Revision 1.148  2014/06/17 17:38:48  brouard
                    328:   Summary: Nothing new
                    329:   Author: Brouard
                    330: 
                    331:   Just a new packaging for OS/X version 0.98nS
                    332: 
1.148     brouard   333:   Revision 1.147  2014/06/16 10:33:11  brouard
                    334:   *** empty log message ***
                    335: 
1.147     brouard   336:   Revision 1.146  2014/06/16 10:20:28  brouard
                    337:   Summary: Merge
                    338:   Author: Brouard
                    339: 
                    340:   Merge, before building revised version.
                    341: 
1.146     brouard   342:   Revision 1.145  2014/06/10 21:23:15  brouard
                    343:   Summary: Debugging with valgrind
                    344:   Author: Nicolas Brouard
                    345: 
                    346:   Lot of changes in order to output the results with some covariates
                    347:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    348:   improve the code.
                    349:   No more memory valgrind error but a lot has to be done in order to
                    350:   continue the work of splitting the code into subroutines.
                    351:   Also, decodemodel has been improved. Tricode is still not
                    352:   optimal. nbcode should be improved. Documentation has been added in
                    353:   the source code.
                    354: 
1.144     brouard   355:   Revision 1.143  2014/01/26 09:45:38  brouard
                    356:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    357: 
                    358:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    359:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    360: 
1.143     brouard   361:   Revision 1.142  2014/01/26 03:57:36  brouard
                    362:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    363: 
                    364:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    365: 
1.142     brouard   366:   Revision 1.141  2014/01/26 02:42:01  brouard
                    367:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    368: 
1.141     brouard   369:   Revision 1.140  2011/09/02 10:37:54  brouard
                    370:   Summary: times.h is ok with mingw32 now.
                    371: 
1.140     brouard   372:   Revision 1.139  2010/06/14 07:50:17  brouard
                    373:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    374:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    375: 
1.139     brouard   376:   Revision 1.138  2010/04/30 18:19:40  brouard
                    377:   *** empty log message ***
                    378: 
1.138     brouard   379:   Revision 1.137  2010/04/29 18:11:38  brouard
                    380:   (Module): Checking covariates for more complex models
                    381:   than V1+V2. A lot of change to be done. Unstable.
                    382: 
1.137     brouard   383:   Revision 1.136  2010/04/26 20:30:53  brouard
                    384:   (Module): merging some libgsl code. Fixing computation
                    385:   of likelione (using inter/intrapolation if mle = 0) in order to
                    386:   get same likelihood as if mle=1.
                    387:   Some cleaning of code and comments added.
                    388: 
1.136     brouard   389:   Revision 1.135  2009/10/29 15:33:14  brouard
                    390:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    391: 
1.135     brouard   392:   Revision 1.134  2009/10/29 13:18:53  brouard
                    393:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    394: 
1.134     brouard   395:   Revision 1.133  2009/07/06 10:21:25  brouard
                    396:   just nforces
                    397: 
1.133     brouard   398:   Revision 1.132  2009/07/06 08:22:05  brouard
                    399:   Many tings
                    400: 
1.132     brouard   401:   Revision 1.131  2009/06/20 16:22:47  brouard
                    402:   Some dimensions resccaled
                    403: 
1.131     brouard   404:   Revision 1.130  2009/05/26 06:44:34  brouard
                    405:   (Module): Max Covariate is now set to 20 instead of 8. A
                    406:   lot of cleaning with variables initialized to 0. Trying to make
                    407:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    408: 
1.130     brouard   409:   Revision 1.129  2007/08/31 13:49:27  lievre
                    410:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    411: 
1.129     lievre    412:   Revision 1.128  2006/06/30 13:02:05  brouard
                    413:   (Module): Clarifications on computing e.j
                    414: 
1.128     brouard   415:   Revision 1.127  2006/04/28 18:11:50  brouard
                    416:   (Module): Yes the sum of survivors was wrong since
                    417:   imach-114 because nhstepm was no more computed in the age
                    418:   loop. Now we define nhstepma in the age loop.
                    419:   (Module): In order to speed up (in case of numerous covariates) we
                    420:   compute health expectancies (without variances) in a first step
                    421:   and then all the health expectancies with variances or standard
                    422:   deviation (needs data from the Hessian matrices) which slows the
                    423:   computation.
                    424:   In the future we should be able to stop the program is only health
                    425:   expectancies and graph are needed without standard deviations.
                    426: 
1.127     brouard   427:   Revision 1.126  2006/04/28 17:23:28  brouard
                    428:   (Module): Yes the sum of survivors was wrong since
                    429:   imach-114 because nhstepm was no more computed in the age
                    430:   loop. Now we define nhstepma in the age loop.
                    431:   Version 0.98h
                    432: 
1.126     brouard   433:   Revision 1.125  2006/04/04 15:20:31  lievre
                    434:   Errors in calculation of health expectancies. Age was not initialized.
                    435:   Forecasting file added.
                    436: 
                    437:   Revision 1.124  2006/03/22 17:13:53  lievre
                    438:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    439:   The log-likelihood is printed in the log file
                    440: 
                    441:   Revision 1.123  2006/03/20 10:52:43  brouard
                    442:   * imach.c (Module): <title> changed, corresponds to .htm file
                    443:   name. <head> headers where missing.
                    444: 
                    445:   * imach.c (Module): Weights can have a decimal point as for
                    446:   English (a comma might work with a correct LC_NUMERIC environment,
                    447:   otherwise the weight is truncated).
                    448:   Modification of warning when the covariates values are not 0 or
                    449:   1.
                    450:   Version 0.98g
                    451: 
                    452:   Revision 1.122  2006/03/20 09:45:41  brouard
                    453:   (Module): Weights can have a decimal point as for
                    454:   English (a comma might work with a correct LC_NUMERIC environment,
                    455:   otherwise the weight is truncated).
                    456:   Modification of warning when the covariates values are not 0 or
                    457:   1.
                    458:   Version 0.98g
                    459: 
                    460:   Revision 1.121  2006/03/16 17:45:01  lievre
                    461:   * imach.c (Module): Comments concerning covariates added
                    462: 
                    463:   * imach.c (Module): refinements in the computation of lli if
                    464:   status=-2 in order to have more reliable computation if stepm is
                    465:   not 1 month. Version 0.98f
                    466: 
                    467:   Revision 1.120  2006/03/16 15:10:38  lievre
                    468:   (Module): refinements in the computation of lli if
                    469:   status=-2 in order to have more reliable computation if stepm is
                    470:   not 1 month. Version 0.98f
                    471: 
                    472:   Revision 1.119  2006/03/15 17:42:26  brouard
                    473:   (Module): Bug if status = -2, the loglikelihood was
                    474:   computed as likelihood omitting the logarithm. Version O.98e
                    475: 
                    476:   Revision 1.118  2006/03/14 18:20:07  brouard
                    477:   (Module): varevsij Comments added explaining the second
                    478:   table of variances if popbased=1 .
                    479:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    480:   (Module): Function pstamp added
                    481:   (Module): Version 0.98d
                    482: 
                    483:   Revision 1.117  2006/03/14 17:16:22  brouard
                    484:   (Module): varevsij Comments added explaining the second
                    485:   table of variances if popbased=1 .
                    486:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    487:   (Module): Function pstamp added
                    488:   (Module): Version 0.98d
                    489: 
                    490:   Revision 1.116  2006/03/06 10:29:27  brouard
                    491:   (Module): Variance-covariance wrong links and
                    492:   varian-covariance of ej. is needed (Saito).
                    493: 
                    494:   Revision 1.115  2006/02/27 12:17:45  brouard
                    495:   (Module): One freematrix added in mlikeli! 0.98c
                    496: 
                    497:   Revision 1.114  2006/02/26 12:57:58  brouard
                    498:   (Module): Some improvements in processing parameter
                    499:   filename with strsep.
                    500: 
                    501:   Revision 1.113  2006/02/24 14:20:24  brouard
                    502:   (Module): Memory leaks checks with valgrind and:
                    503:   datafile was not closed, some imatrix were not freed and on matrix
                    504:   allocation too.
                    505: 
                    506:   Revision 1.112  2006/01/30 09:55:26  brouard
                    507:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    508: 
                    509:   Revision 1.111  2006/01/25 20:38:18  brouard
                    510:   (Module): Lots of cleaning and bugs added (Gompertz)
                    511:   (Module): Comments can be added in data file. Missing date values
                    512:   can be a simple dot '.'.
                    513: 
                    514:   Revision 1.110  2006/01/25 00:51:50  brouard
                    515:   (Module): Lots of cleaning and bugs added (Gompertz)
                    516: 
                    517:   Revision 1.109  2006/01/24 19:37:15  brouard
                    518:   (Module): Comments (lines starting with a #) are allowed in data.
                    519: 
                    520:   Revision 1.108  2006/01/19 18:05:42  lievre
                    521:   Gnuplot problem appeared...
                    522:   To be fixed
                    523: 
                    524:   Revision 1.107  2006/01/19 16:20:37  brouard
                    525:   Test existence of gnuplot in imach path
                    526: 
                    527:   Revision 1.106  2006/01/19 13:24:36  brouard
                    528:   Some cleaning and links added in html output
                    529: 
                    530:   Revision 1.105  2006/01/05 20:23:19  lievre
                    531:   *** empty log message ***
                    532: 
                    533:   Revision 1.104  2005/09/30 16:11:43  lievre
                    534:   (Module): sump fixed, loop imx fixed, and simplifications.
                    535:   (Module): If the status is missing at the last wave but we know
                    536:   that the person is alive, then we can code his/her status as -2
                    537:   (instead of missing=-1 in earlier versions) and his/her
                    538:   contributions to the likelihood is 1 - Prob of dying from last
                    539:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    540:   the healthy state at last known wave). Version is 0.98
                    541: 
                    542:   Revision 1.103  2005/09/30 15:54:49  lievre
                    543:   (Module): sump fixed, loop imx fixed, and simplifications.
                    544: 
                    545:   Revision 1.102  2004/09/15 17:31:30  brouard
                    546:   Add the possibility to read data file including tab characters.
                    547: 
                    548:   Revision 1.101  2004/09/15 10:38:38  brouard
                    549:   Fix on curr_time
                    550: 
                    551:   Revision 1.100  2004/07/12 18:29:06  brouard
                    552:   Add version for Mac OS X. Just define UNIX in Makefile
                    553: 
                    554:   Revision 1.99  2004/06/05 08:57:40  brouard
                    555:   *** empty log message ***
                    556: 
                    557:   Revision 1.98  2004/05/16 15:05:56  brouard
                    558:   New version 0.97 . First attempt to estimate force of mortality
                    559:   directly from the data i.e. without the need of knowing the health
                    560:   state at each age, but using a Gompertz model: log u =a + b*age .
                    561:   This is the basic analysis of mortality and should be done before any
                    562:   other analysis, in order to test if the mortality estimated from the
                    563:   cross-longitudinal survey is different from the mortality estimated
                    564:   from other sources like vital statistic data.
                    565: 
                    566:   The same imach parameter file can be used but the option for mle should be -3.
                    567: 
1.133     brouard   568:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   569:   former routines in order to include the new code within the former code.
                    570: 
                    571:   The output is very simple: only an estimate of the intercept and of
                    572:   the slope with 95% confident intervals.
                    573: 
                    574:   Current limitations:
                    575:   A) Even if you enter covariates, i.e. with the
                    576:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    577:   B) There is no computation of Life Expectancy nor Life Table.
                    578: 
                    579:   Revision 1.97  2004/02/20 13:25:42  lievre
                    580:   Version 0.96d. Population forecasting command line is (temporarily)
                    581:   suppressed.
                    582: 
                    583:   Revision 1.96  2003/07/15 15:38:55  brouard
                    584:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    585:   rewritten within the same printf. Workaround: many printfs.
                    586: 
                    587:   Revision 1.95  2003/07/08 07:54:34  brouard
                    588:   * imach.c (Repository):
                    589:   (Repository): Using imachwizard code to output a more meaningful covariance
                    590:   matrix (cov(a12,c31) instead of numbers.
                    591: 
                    592:   Revision 1.94  2003/06/27 13:00:02  brouard
                    593:   Just cleaning
                    594: 
                    595:   Revision 1.93  2003/06/25 16:33:55  brouard
                    596:   (Module): On windows (cygwin) function asctime_r doesn't
                    597:   exist so I changed back to asctime which exists.
                    598:   (Module): Version 0.96b
                    599: 
                    600:   Revision 1.92  2003/06/25 16:30:45  brouard
                    601:   (Module): On windows (cygwin) function asctime_r doesn't
                    602:   exist so I changed back to asctime which exists.
                    603: 
                    604:   Revision 1.91  2003/06/25 15:30:29  brouard
                    605:   * imach.c (Repository): Duplicated warning errors corrected.
                    606:   (Repository): Elapsed time after each iteration is now output. It
                    607:   helps to forecast when convergence will be reached. Elapsed time
                    608:   is stamped in powell.  We created a new html file for the graphs
                    609:   concerning matrix of covariance. It has extension -cov.htm.
                    610: 
                    611:   Revision 1.90  2003/06/24 12:34:15  brouard
                    612:   (Module): Some bugs corrected for windows. Also, when
                    613:   mle=-1 a template is output in file "or"mypar.txt with the design
                    614:   of the covariance matrix to be input.
                    615: 
                    616:   Revision 1.89  2003/06/24 12:30:52  brouard
                    617:   (Module): Some bugs corrected for windows. Also, when
                    618:   mle=-1 a template is output in file "or"mypar.txt with the design
                    619:   of the covariance matrix to be input.
                    620: 
                    621:   Revision 1.88  2003/06/23 17:54:56  brouard
                    622:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    623: 
                    624:   Revision 1.87  2003/06/18 12:26:01  brouard
                    625:   Version 0.96
                    626: 
                    627:   Revision 1.86  2003/06/17 20:04:08  brouard
                    628:   (Module): Change position of html and gnuplot routines and added
                    629:   routine fileappend.
                    630: 
                    631:   Revision 1.85  2003/06/17 13:12:43  brouard
                    632:   * imach.c (Repository): Check when date of death was earlier that
                    633:   current date of interview. It may happen when the death was just
                    634:   prior to the death. In this case, dh was negative and likelihood
                    635:   was wrong (infinity). We still send an "Error" but patch by
                    636:   assuming that the date of death was just one stepm after the
                    637:   interview.
                    638:   (Repository): Because some people have very long ID (first column)
                    639:   we changed int to long in num[] and we added a new lvector for
                    640:   memory allocation. But we also truncated to 8 characters (left
                    641:   truncation)
                    642:   (Repository): No more line truncation errors.
                    643: 
                    644:   Revision 1.84  2003/06/13 21:44:43  brouard
                    645:   * imach.c (Repository): Replace "freqsummary" at a correct
                    646:   place. It differs from routine "prevalence" which may be called
                    647:   many times. Probs is memory consuming and must be used with
                    648:   parcimony.
                    649:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    650: 
                    651:   Revision 1.83  2003/06/10 13:39:11  lievre
                    652:   *** empty log message ***
                    653: 
                    654:   Revision 1.82  2003/06/05 15:57:20  brouard
                    655:   Add log in  imach.c and  fullversion number is now printed.
                    656: 
                    657: */
                    658: /*
                    659:    Interpolated Markov Chain
                    660: 
                    661:   Short summary of the programme:
                    662:   
1.227     brouard   663:   This program computes Healthy Life Expectancies or State-specific
                    664:   (if states aren't health statuses) Expectancies from
                    665:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    666: 
                    667:   -1- a first survey ("cross") where individuals from different ages
                    668:   are interviewed on their health status or degree of disability (in
                    669:   the case of a health survey which is our main interest)
                    670: 
                    671:   -2- at least a second wave of interviews ("longitudinal") which
                    672:   measure each change (if any) in individual health status.  Health
                    673:   expectancies are computed from the time spent in each health state
                    674:   according to a model. More health states you consider, more time is
                    675:   necessary to reach the Maximum Likelihood of the parameters involved
                    676:   in the model.  The simplest model is the multinomial logistic model
                    677:   where pij is the probability to be observed in state j at the second
                    678:   wave conditional to be observed in state i at the first
                    679:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    680:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    681:   have a more complex model than "constant and age", you should modify
                    682:   the program where the markup *Covariates have to be included here
                    683:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   684:   convergence.
                    685: 
                    686:   The advantage of this computer programme, compared to a simple
                    687:   multinomial logistic model, is clear when the delay between waves is not
                    688:   identical for each individual. Also, if a individual missed an
                    689:   intermediate interview, the information is lost, but taken into
                    690:   account using an interpolation or extrapolation.  
                    691: 
                    692:   hPijx is the probability to be observed in state i at age x+h
                    693:   conditional to the observed state i at age x. The delay 'h' can be
                    694:   split into an exact number (nh*stepm) of unobserved intermediate
                    695:   states. This elementary transition (by month, quarter,
                    696:   semester or year) is modelled as a multinomial logistic.  The hPx
                    697:   matrix is simply the matrix product of nh*stepm elementary matrices
                    698:   and the contribution of each individual to the likelihood is simply
                    699:   hPijx.
                    700: 
                    701:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   702:   of the life expectancies. It also computes the period (stable) prevalence.
                    703: 
                    704: Back prevalence and projections:
1.227     brouard   705: 
                    706:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    707:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    708:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    709:    mobilavproj)
                    710: 
                    711:     Computes the back prevalence limit for any combination of
                    712:     covariate values k at any age between ageminpar and agemaxpar and
                    713:     returns it in **bprlim. In the loops,
                    714: 
                    715:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    716:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    717: 
                    718:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   719:    Computes for any combination of covariates k and any age between bage and fage 
                    720:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    721:                        oldm=oldms;savm=savms;
1.227     brouard   722: 
                    723:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   724:      Computes the transition matrix starting at age 'age' over
                    725:      'nhstepm*hstepm*stepm' months (i.e. until
                    726:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   727:      nhstepm*hstepm matrices. 
                    728: 
                    729:      Returns p3mat[i][j][h] after calling
                    730:      p3mat[i][j][h]=matprod2(newm,
                    731:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    732:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    733:      oldm);
1.226     brouard   734: 
                    735: Important routines
                    736: 
                    737: - func (or funcone), computes logit (pij) distinguishing
                    738:   o fixed variables (single or product dummies or quantitative);
                    739:   o varying variables by:
                    740:    (1) wave (single, product dummies, quantitative), 
                    741:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    742:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    743:        % varying dummy (not done) or quantitative (not done);
                    744: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    745:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    746: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    747:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    748:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   749: 
1.226     brouard   750: 
                    751:   
1.133     brouard   752:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    753:            Institut national d'études démographiques, Paris.
1.126     brouard   754:   This software have been partly granted by Euro-REVES, a concerted action
                    755:   from the European Union.
                    756:   It is copyrighted identically to a GNU software product, ie programme and
                    757:   software can be distributed freely for non commercial use. Latest version
                    758:   can be accessed at http://euroreves.ined.fr/imach .
                    759: 
                    760:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    761:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    762:   
                    763:   **********************************************************************/
                    764: /*
                    765:   main
                    766:   read parameterfile
                    767:   read datafile
                    768:   concatwav
                    769:   freqsummary
                    770:   if (mle >= 1)
                    771:     mlikeli
                    772:   print results files
                    773:   if mle==1 
                    774:      computes hessian
                    775:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    776:       begin-prev-date,...
                    777:   open gnuplot file
                    778:   open html file
1.145     brouard   779:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    780:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    781:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    782:     freexexit2 possible for memory heap.
                    783: 
                    784:   h Pij x                         | pij_nom  ficrestpij
                    785:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    786:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    787:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    788: 
                    789:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    790:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    791:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    792:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    793:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    794: 
1.126     brouard   795:   forecasting if prevfcast==1 prevforecast call prevalence()
                    796:   health expectancies
                    797:   Variance-covariance of DFLE
                    798:   prevalence()
                    799:    movingaverage()
                    800:   varevsij() 
                    801:   if popbased==1 varevsij(,popbased)
                    802:   total life expectancies
                    803:   Variance of period (stable) prevalence
                    804:  end
                    805: */
                    806: 
1.187     brouard   807: /* #define DEBUG */
                    808: /* #define DEBUGBRENT */
1.203     brouard   809: /* #define DEBUGLINMIN */
                    810: /* #define DEBUGHESS */
                    811: #define DEBUGHESSIJ
1.224     brouard   812: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   813: #define POWELL /* Instead of NLOPT */
1.224     brouard   814: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   815: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    816: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   817: 
                    818: #include <math.h>
                    819: #include <stdio.h>
                    820: #include <stdlib.h>
                    821: #include <string.h>
1.226     brouard   822: #include <ctype.h>
1.159     brouard   823: 
                    824: #ifdef _WIN32
                    825: #include <io.h>
1.172     brouard   826: #include <windows.h>
                    827: #include <tchar.h>
1.159     brouard   828: #else
1.126     brouard   829: #include <unistd.h>
1.159     brouard   830: #endif
1.126     brouard   831: 
                    832: #include <limits.h>
                    833: #include <sys/types.h>
1.171     brouard   834: 
                    835: #if defined(__GNUC__)
                    836: #include <sys/utsname.h> /* Doesn't work on Windows */
                    837: #endif
                    838: 
1.126     brouard   839: #include <sys/stat.h>
                    840: #include <errno.h>
1.159     brouard   841: /* extern int errno; */
1.126     brouard   842: 
1.157     brouard   843: /* #ifdef LINUX */
                    844: /* #include <time.h> */
                    845: /* #include "timeval.h" */
                    846: /* #else */
                    847: /* #include <sys/time.h> */
                    848: /* #endif */
                    849: 
1.126     brouard   850: #include <time.h>
                    851: 
1.136     brouard   852: #ifdef GSL
                    853: #include <gsl/gsl_errno.h>
                    854: #include <gsl/gsl_multimin.h>
                    855: #endif
                    856: 
1.167     brouard   857: 
1.162     brouard   858: #ifdef NLOPT
                    859: #include <nlopt.h>
                    860: typedef struct {
                    861:   double (* function)(double [] );
                    862: } myfunc_data ;
                    863: #endif
                    864: 
1.126     brouard   865: /* #include <libintl.h> */
                    866: /* #define _(String) gettext (String) */
                    867: 
1.141     brouard   868: #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   869: 
                    870: #define GNUPLOTPROGRAM "gnuplot"
                    871: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    872: #define FILENAMELENGTH 132
                    873: 
                    874: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    875: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    876: 
1.144     brouard   877: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    878: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   879: 
                    880: #define NINTERVMAX 8
1.144     brouard   881: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    882: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    883: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   884: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   885: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    886: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   887: #define MAXN 20000
1.144     brouard   888: #define YEARM 12. /**< Number of months per year */
1.218     brouard   889: /* #define AGESUP 130 */
                    890: #define AGESUP 150
                    891: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   892: #define AGEBASE 40
1.194     brouard   893: #define AGEOVERFLOW 1.e20
1.164     brouard   894: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   895: #ifdef _WIN32
                    896: #define DIRSEPARATOR '\\'
                    897: #define CHARSEPARATOR "\\"
                    898: #define ODIRSEPARATOR '/'
                    899: #else
1.126     brouard   900: #define DIRSEPARATOR '/'
                    901: #define CHARSEPARATOR "/"
                    902: #define ODIRSEPARATOR '\\'
                    903: #endif
                    904: 
1.235   ! brouard   905: /* $Id: imach.c,v 1.234 2016/08/23 16:51:20 brouard Exp $ */
1.126     brouard   906: /* $State: Exp $ */
1.196     brouard   907: #include "version.h"
                    908: char version[]=__IMACH_VERSION__;
1.224     brouard   909: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.235   ! brouard   910: char fullversion[]="$Revision: 1.234 $ $Date: 2016/08/23 16:51:20 $"; 
1.126     brouard   911: char strstart[80];
                    912: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   913: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   914: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   915: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    916: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    917: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   918: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    919: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   920: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    921: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    922: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   923: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    924: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   925: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   926: int nsd=0; /**< Total number of single dummy variables (output) */
                    927: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   928: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   929: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   930: int ntveff=0; /**< ntveff number of effective time varying variables */
                    931: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   932: int cptcov=0; /* Working variable */
1.218     brouard   933: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   934: int npar=NPARMAX;
                    935: int nlstate=2; /* Number of live states */
                    936: int ndeath=1; /* Number of dead states */
1.130     brouard   937: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   938: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   939: int popbased=0;
                    940: 
                    941: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   942: int maxwav=0; /* Maxim number of waves */
                    943: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                    944: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                    945: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard   946:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard   947: int mle=1, weightopt=0;
1.126     brouard   948: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                    949: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                    950: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                    951:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard   952: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard   953: int selected(int kvar); /* Is covariate kvar selected for printing results */
                    954: 
1.130     brouard   955: double jmean=1; /* Mean space between 2 waves */
1.145     brouard   956: double **matprod2(); /* test */
1.126     brouard   957: double **oldm, **newm, **savm; /* Working pointers to matrices */
                    958: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard   959: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                    960: 
1.136     brouard   961: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard   962: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard   963: FILE *ficlog, *ficrespow;
1.130     brouard   964: int globpr=0; /* Global variable for printing or not */
1.126     brouard   965: double fretone; /* Only one call to likelihood */
1.130     brouard   966: long ipmx=0; /* Number of contributions */
1.126     brouard   967: double sw; /* Sum of weights */
                    968: char filerespow[FILENAMELENGTH];
                    969: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                    970: FILE *ficresilk;
                    971: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                    972: FILE *ficresprobmorprev;
                    973: FILE *fichtm, *fichtmcov; /* Html File */
                    974: FILE *ficreseij;
                    975: char filerese[FILENAMELENGTH];
                    976: FILE *ficresstdeij;
                    977: char fileresstde[FILENAMELENGTH];
                    978: FILE *ficrescveij;
                    979: char filerescve[FILENAMELENGTH];
                    980: FILE  *ficresvij;
                    981: char fileresv[FILENAMELENGTH];
                    982: FILE  *ficresvpl;
                    983: char fileresvpl[FILENAMELENGTH];
                    984: char title[MAXLINE];
1.234     brouard   985: char model[MAXLINE]; /**< The model line */
1.217     brouard   986: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard   987: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                    988: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                    989: char command[FILENAMELENGTH];
                    990: int  outcmd=0;
                    991: 
1.217     brouard   992: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard   993: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard   994: char filelog[FILENAMELENGTH]; /* Log file */
                    995: char filerest[FILENAMELENGTH];
                    996: char fileregp[FILENAMELENGTH];
                    997: char popfile[FILENAMELENGTH];
                    998: 
                    999: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1000: 
1.157     brouard  1001: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1002: /* struct timezone tzp; */
                   1003: /* extern int gettimeofday(); */
                   1004: struct tm tml, *gmtime(), *localtime();
                   1005: 
                   1006: extern time_t time();
                   1007: 
                   1008: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1009: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1010: struct tm tm;
                   1011: 
1.126     brouard  1012: char strcurr[80], strfor[80];
                   1013: 
                   1014: char *endptr;
                   1015: long lval;
                   1016: double dval;
                   1017: 
                   1018: #define NR_END 1
                   1019: #define FREE_ARG char*
                   1020: #define FTOL 1.0e-10
                   1021: 
                   1022: #define NRANSI 
                   1023: #define ITMAX 200 
                   1024: 
                   1025: #define TOL 2.0e-4 
                   1026: 
                   1027: #define CGOLD 0.3819660 
                   1028: #define ZEPS 1.0e-10 
                   1029: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1030: 
                   1031: #define GOLD 1.618034 
                   1032: #define GLIMIT 100.0 
                   1033: #define TINY 1.0e-20 
                   1034: 
                   1035: static double maxarg1,maxarg2;
                   1036: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1037: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1038:   
                   1039: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1040: #define rint(a) floor(a+0.5)
1.166     brouard  1041: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1042: #define mytinydouble 1.0e-16
1.166     brouard  1043: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1044: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1045: /* static double dsqrarg; */
                   1046: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1047: static double sqrarg;
                   1048: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1049: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1050: int agegomp= AGEGOMP;
                   1051: 
                   1052: int imx; 
                   1053: int stepm=1;
                   1054: /* Stepm, step in month: minimum step interpolation*/
                   1055: 
                   1056: int estepm;
                   1057: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1058: 
                   1059: int m,nb;
                   1060: long *num;
1.197     brouard  1061: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1062: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1063:                   covariate for which somebody answered excluding 
                   1064:                   undefined. Usually 2: 0 and 1. */
                   1065: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1066:                             covariate for which somebody answered including 
                   1067:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1068: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1069: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1070: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1071: double *ageexmed,*agecens;
                   1072: double dateintmean=0;
                   1073: 
                   1074: double *weight;
                   1075: int **s; /* Status */
1.141     brouard  1076: double *agedc;
1.145     brouard  1077: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1078:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1079:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1080: double **coqvar; /* Fixed quantitative covariate iqv */
                   1081: double ***cotvar; /* Time varying covariate itv */
                   1082: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1083: double  idx; 
                   1084: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1085: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1086: /*k          1  2   3   4     5    6    7     8    9 */
                   1087: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1088: /* Tndvar[k]    1   2   3               4          5 */
                   1089: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1090: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1091: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1092: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1093: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1094: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1095: /* Tprod[i]=k           4               7            */
                   1096: /* Tage[i]=k                  5               8      */
                   1097: /* */
                   1098: /* Type                    */
                   1099: /* V         1  2  3  4  5 */
                   1100: /*           F  F  V  V  V */
                   1101: /*           D  Q  D  D  Q */
                   1102: /*                         */
                   1103: int *TvarsD;
                   1104: int *TvarsDind;
                   1105: int *TvarsQ;
                   1106: int *TvarsQind;
                   1107: 
1.235   ! brouard  1108: #define MAXRESULTLINES 10
        !          1109: int nresult=0;
        !          1110: int TKresult[MAXRESULTLINES];
        !          1111: double Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
        !          1112: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
        !          1113: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
        !          1114: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
        !          1115: 
1.234     brouard  1116: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1117: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1118: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1119: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1120: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1121: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1122: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1123: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1124: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1125: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1126: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1127: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1128: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1129: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1130: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1131: 
1.230     brouard  1132: int *Tvarsel; /**< Selected covariates for output */
                   1133: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1134: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1135: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1136: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.197     brouard  1137: int *Tage;
1.227     brouard  1138: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1139: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1140: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1141: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1142: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1143: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1144: int **Tvard;
                   1145: int *Tprod;/**< Gives the k position of the k1 product */
                   1146: int *Tposprod; /**< Gives the k1 product from the k position */
                   1147: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   1148:    if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
                   1149:    Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
                   1150: */
                   1151: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1152: double *lsurv, *lpop, *tpop;
                   1153: 
1.231     brouard  1154: #define FD 1; /* Fixed dummy covariate */
                   1155: #define FQ 2; /* Fixed quantitative covariate */
                   1156: #define FP 3; /* Fixed product covariate */
                   1157: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1158: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1159: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1160: #define VD 10; /* Varying dummy covariate */
                   1161: #define VQ 11; /* Varying quantitative covariate */
                   1162: #define VP 12; /* Varying product covariate */
                   1163: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1164: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1165: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1166: #define APFD 16; /* Age product * fixed dummy covariate */
                   1167: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1168: #define APVD 18; /* Age product * varying dummy covariate */
                   1169: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1170: 
                   1171: #define FTYPE 1; /* Fixed covariate */
                   1172: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1173: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1174: 
                   1175: struct kmodel{
                   1176:        int maintype; /* main type */
                   1177:        int subtype; /* subtype */
                   1178: };
                   1179: struct kmodel modell[NCOVMAX];
                   1180: 
1.143     brouard  1181: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1182: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1183: 
                   1184: /**************** split *************************/
                   1185: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1186: {
                   1187:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1188:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1189:   */ 
                   1190:   char *ss;                            /* pointer */
1.186     brouard  1191:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1192: 
                   1193:   l1 = strlen(path );                  /* length of path */
                   1194:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1195:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1196:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1197:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1198:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1199:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1200:     /* get current working directory */
                   1201:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1202: #ifdef WIN32
                   1203:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1204: #else
                   1205:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1206: #endif
1.126     brouard  1207:       return( GLOCK_ERROR_GETCWD );
                   1208:     }
                   1209:     /* got dirc from getcwd*/
                   1210:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1211:   } else {                             /* strip directory from path */
1.126     brouard  1212:     ss++;                              /* after this, the filename */
                   1213:     l2 = strlen( ss );                 /* length of filename */
                   1214:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1215:     strcpy( name, ss );                /* save file name */
                   1216:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1217:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1218:     printf(" DIRC2 = %s \n",dirc);
                   1219:   }
                   1220:   /* We add a separator at the end of dirc if not exists */
                   1221:   l1 = strlen( dirc );                 /* length of directory */
                   1222:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1223:     dirc[l1] =  DIRSEPARATOR;
                   1224:     dirc[l1+1] = 0; 
                   1225:     printf(" DIRC3 = %s \n",dirc);
                   1226:   }
                   1227:   ss = strrchr( name, '.' );           /* find last / */
                   1228:   if (ss >0){
                   1229:     ss++;
                   1230:     strcpy(ext,ss);                    /* save extension */
                   1231:     l1= strlen( name);
                   1232:     l2= strlen(ss)+1;
                   1233:     strncpy( finame, name, l1-l2);
                   1234:     finame[l1-l2]= 0;
                   1235:   }
                   1236: 
                   1237:   return( 0 );                         /* we're done */
                   1238: }
                   1239: 
                   1240: 
                   1241: /******************************************/
                   1242: 
                   1243: void replace_back_to_slash(char *s, char*t)
                   1244: {
                   1245:   int i;
                   1246:   int lg=0;
                   1247:   i=0;
                   1248:   lg=strlen(t);
                   1249:   for(i=0; i<= lg; i++) {
                   1250:     (s[i] = t[i]);
                   1251:     if (t[i]== '\\') s[i]='/';
                   1252:   }
                   1253: }
                   1254: 
1.132     brouard  1255: char *trimbb(char *out, char *in)
1.137     brouard  1256: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1257:   char *s;
                   1258:   s=out;
                   1259:   while (*in != '\0'){
1.137     brouard  1260:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1261:       in++;
                   1262:     }
                   1263:     *out++ = *in++;
                   1264:   }
                   1265:   *out='\0';
                   1266:   return s;
                   1267: }
                   1268: 
1.187     brouard  1269: /* char *substrchaine(char *out, char *in, char *chain) */
                   1270: /* { */
                   1271: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1272: /*   char *s, *t; */
                   1273: /*   t=in;s=out; */
                   1274: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1275: /*     *out++ = *in++; */
                   1276: /*   } */
                   1277: 
                   1278: /*   /\* *in matches *chain *\/ */
                   1279: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1280: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1281: /*   } */
                   1282: /*   in--; chain--; */
                   1283: /*   while ( (*in != '\0')){ */
                   1284: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1285: /*     *out++ = *in++; */
                   1286: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1287: /*   } */
                   1288: /*   *out='\0'; */
                   1289: /*   out=s; */
                   1290: /*   return out; */
                   1291: /* } */
                   1292: char *substrchaine(char *out, char *in, char *chain)
                   1293: {
                   1294:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1295:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1296: 
                   1297:   char *strloc;
                   1298: 
                   1299:   strcpy (out, in); 
                   1300:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1301:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1302:   if(strloc != NULL){ 
                   1303:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1304:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1305:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1306:   }
                   1307:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1308:   return out;
                   1309: }
                   1310: 
                   1311: 
1.145     brouard  1312: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1313: {
1.187     brouard  1314:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1315:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1316:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1317:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1318:   */
1.160     brouard  1319:   char *s, *t;
1.145     brouard  1320:   t=in;s=in;
                   1321:   while ((*in != occ) && (*in != '\0')){
                   1322:     *alocc++ = *in++;
                   1323:   }
                   1324:   if( *in == occ){
                   1325:     *(alocc)='\0';
                   1326:     s=++in;
                   1327:   }
                   1328:  
                   1329:   if (s == t) {/* occ not found */
                   1330:     *(alocc-(in-s))='\0';
                   1331:     in=s;
                   1332:   }
                   1333:   while ( *in != '\0'){
                   1334:     *blocc++ = *in++;
                   1335:   }
                   1336: 
                   1337:   *blocc='\0';
                   1338:   return t;
                   1339: }
1.137     brouard  1340: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1341: {
1.187     brouard  1342:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1343:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1344:      gives blocc="abcdef2ghi" and alocc="j".
                   1345:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1346:   */
                   1347:   char *s, *t;
                   1348:   t=in;s=in;
                   1349:   while (*in != '\0'){
                   1350:     while( *in == occ){
                   1351:       *blocc++ = *in++;
                   1352:       s=in;
                   1353:     }
                   1354:     *blocc++ = *in++;
                   1355:   }
                   1356:   if (s == t) /* occ not found */
                   1357:     *(blocc-(in-s))='\0';
                   1358:   else
                   1359:     *(blocc-(in-s)-1)='\0';
                   1360:   in=s;
                   1361:   while ( *in != '\0'){
                   1362:     *alocc++ = *in++;
                   1363:   }
                   1364: 
                   1365:   *alocc='\0';
                   1366:   return s;
                   1367: }
                   1368: 
1.126     brouard  1369: int nbocc(char *s, char occ)
                   1370: {
                   1371:   int i,j=0;
                   1372:   int lg=20;
                   1373:   i=0;
                   1374:   lg=strlen(s);
                   1375:   for(i=0; i<= lg; i++) {
1.234     brouard  1376:     if  (s[i] == occ ) j++;
1.126     brouard  1377:   }
                   1378:   return j;
                   1379: }
                   1380: 
1.137     brouard  1381: /* void cutv(char *u,char *v, char*t, char occ) */
                   1382: /* { */
                   1383: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1384: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1385: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1386: /*   int i,lg,j,p=0; */
                   1387: /*   i=0; */
                   1388: /*   lg=strlen(t); */
                   1389: /*   for(j=0; j<=lg-1; j++) { */
                   1390: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1391: /*   } */
1.126     brouard  1392: 
1.137     brouard  1393: /*   for(j=0; j<p; j++) { */
                   1394: /*     (u[j] = t[j]); */
                   1395: /*   } */
                   1396: /*      u[p]='\0'; */
1.126     brouard  1397: 
1.137     brouard  1398: /*    for(j=0; j<= lg; j++) { */
                   1399: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1400: /*   } */
                   1401: /* } */
1.126     brouard  1402: 
1.160     brouard  1403: #ifdef _WIN32
                   1404: char * strsep(char **pp, const char *delim)
                   1405: {
                   1406:   char *p, *q;
                   1407:          
                   1408:   if ((p = *pp) == NULL)
                   1409:     return 0;
                   1410:   if ((q = strpbrk (p, delim)) != NULL)
                   1411:   {
                   1412:     *pp = q + 1;
                   1413:     *q = '\0';
                   1414:   }
                   1415:   else
                   1416:     *pp = 0;
                   1417:   return p;
                   1418: }
                   1419: #endif
                   1420: 
1.126     brouard  1421: /********************** nrerror ********************/
                   1422: 
                   1423: void nrerror(char error_text[])
                   1424: {
                   1425:   fprintf(stderr,"ERREUR ...\n");
                   1426:   fprintf(stderr,"%s\n",error_text);
                   1427:   exit(EXIT_FAILURE);
                   1428: }
                   1429: /*********************** vector *******************/
                   1430: double *vector(int nl, int nh)
                   1431: {
                   1432:   double *v;
                   1433:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1434:   if (!v) nrerror("allocation failure in vector");
                   1435:   return v-nl+NR_END;
                   1436: }
                   1437: 
                   1438: /************************ free vector ******************/
                   1439: void free_vector(double*v, int nl, int nh)
                   1440: {
                   1441:   free((FREE_ARG)(v+nl-NR_END));
                   1442: }
                   1443: 
                   1444: /************************ivector *******************************/
                   1445: int *ivector(long nl,long nh)
                   1446: {
                   1447:   int *v;
                   1448:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1449:   if (!v) nrerror("allocation failure in ivector");
                   1450:   return v-nl+NR_END;
                   1451: }
                   1452: 
                   1453: /******************free ivector **************************/
                   1454: void free_ivector(int *v, long nl, long nh)
                   1455: {
                   1456:   free((FREE_ARG)(v+nl-NR_END));
                   1457: }
                   1458: 
                   1459: /************************lvector *******************************/
                   1460: long *lvector(long nl,long nh)
                   1461: {
                   1462:   long *v;
                   1463:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1464:   if (!v) nrerror("allocation failure in ivector");
                   1465:   return v-nl+NR_END;
                   1466: }
                   1467: 
                   1468: /******************free lvector **************************/
                   1469: void free_lvector(long *v, long nl, long nh)
                   1470: {
                   1471:   free((FREE_ARG)(v+nl-NR_END));
                   1472: }
                   1473: 
                   1474: /******************* imatrix *******************************/
                   1475: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1476:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1477: { 
                   1478:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1479:   int **m; 
                   1480:   
                   1481:   /* allocate pointers to rows */ 
                   1482:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1483:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1484:   m += NR_END; 
                   1485:   m -= nrl; 
                   1486:   
                   1487:   
                   1488:   /* allocate rows and set pointers to them */ 
                   1489:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1490:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1491:   m[nrl] += NR_END; 
                   1492:   m[nrl] -= ncl; 
                   1493:   
                   1494:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1495:   
                   1496:   /* return pointer to array of pointers to rows */ 
                   1497:   return m; 
                   1498: } 
                   1499: 
                   1500: /****************** free_imatrix *************************/
                   1501: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1502:       int **m;
                   1503:       long nch,ncl,nrh,nrl; 
                   1504:      /* free an int matrix allocated by imatrix() */ 
                   1505: { 
                   1506:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1507:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1508: } 
                   1509: 
                   1510: /******************* matrix *******************************/
                   1511: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1512: {
                   1513:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1514:   double **m;
                   1515: 
                   1516:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1517:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1518:   m += NR_END;
                   1519:   m -= nrl;
                   1520: 
                   1521:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1522:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1523:   m[nrl] += NR_END;
                   1524:   m[nrl] -= ncl;
                   1525: 
                   1526:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1527:   return m;
1.145     brouard  1528:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1529: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1530: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1531:    */
                   1532: }
                   1533: 
                   1534: /*************************free matrix ************************/
                   1535: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1536: {
                   1537:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1538:   free((FREE_ARG)(m+nrl-NR_END));
                   1539: }
                   1540: 
                   1541: /******************* ma3x *******************************/
                   1542: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1543: {
                   1544:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1545:   double ***m;
                   1546: 
                   1547:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1548:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1549:   m += NR_END;
                   1550:   m -= nrl;
                   1551: 
                   1552:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1553:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1554:   m[nrl] += NR_END;
                   1555:   m[nrl] -= ncl;
                   1556: 
                   1557:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1558: 
                   1559:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1560:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1561:   m[nrl][ncl] += NR_END;
                   1562:   m[nrl][ncl] -= nll;
                   1563:   for (j=ncl+1; j<=nch; j++) 
                   1564:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1565:   
                   1566:   for (i=nrl+1; i<=nrh; i++) {
                   1567:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1568:     for (j=ncl+1; j<=nch; j++) 
                   1569:       m[i][j]=m[i][j-1]+nlay;
                   1570:   }
                   1571:   return m; 
                   1572:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1573:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1574:   */
                   1575: }
                   1576: 
                   1577: /*************************free ma3x ************************/
                   1578: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1579: {
                   1580:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1581:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1582:   free((FREE_ARG)(m+nrl-NR_END));
                   1583: }
                   1584: 
                   1585: /*************** function subdirf ***********/
                   1586: char *subdirf(char fileres[])
                   1587: {
                   1588:   /* Caution optionfilefiname is hidden */
                   1589:   strcpy(tmpout,optionfilefiname);
                   1590:   strcat(tmpout,"/"); /* Add to the right */
                   1591:   strcat(tmpout,fileres);
                   1592:   return tmpout;
                   1593: }
                   1594: 
                   1595: /*************** function subdirf2 ***********/
                   1596: char *subdirf2(char fileres[], char *preop)
                   1597: {
                   1598:   
                   1599:   /* Caution optionfilefiname is hidden */
                   1600:   strcpy(tmpout,optionfilefiname);
                   1601:   strcat(tmpout,"/");
                   1602:   strcat(tmpout,preop);
                   1603:   strcat(tmpout,fileres);
                   1604:   return tmpout;
                   1605: }
                   1606: 
                   1607: /*************** function subdirf3 ***********/
                   1608: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1609: {
                   1610:   
                   1611:   /* Caution optionfilefiname is hidden */
                   1612:   strcpy(tmpout,optionfilefiname);
                   1613:   strcat(tmpout,"/");
                   1614:   strcat(tmpout,preop);
                   1615:   strcat(tmpout,preop2);
                   1616:   strcat(tmpout,fileres);
                   1617:   return tmpout;
                   1618: }
1.213     brouard  1619:  
                   1620: /*************** function subdirfext ***********/
                   1621: char *subdirfext(char fileres[], char *preop, char *postop)
                   1622: {
                   1623:   
                   1624:   strcpy(tmpout,preop);
                   1625:   strcat(tmpout,fileres);
                   1626:   strcat(tmpout,postop);
                   1627:   return tmpout;
                   1628: }
1.126     brouard  1629: 
1.213     brouard  1630: /*************** function subdirfext3 ***********/
                   1631: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1632: {
                   1633:   
                   1634:   /* Caution optionfilefiname is hidden */
                   1635:   strcpy(tmpout,optionfilefiname);
                   1636:   strcat(tmpout,"/");
                   1637:   strcat(tmpout,preop);
                   1638:   strcat(tmpout,fileres);
                   1639:   strcat(tmpout,postop);
                   1640:   return tmpout;
                   1641: }
                   1642:  
1.162     brouard  1643: char *asc_diff_time(long time_sec, char ascdiff[])
                   1644: {
                   1645:   long sec_left, days, hours, minutes;
                   1646:   days = (time_sec) / (60*60*24);
                   1647:   sec_left = (time_sec) % (60*60*24);
                   1648:   hours = (sec_left) / (60*60) ;
                   1649:   sec_left = (sec_left) %(60*60);
                   1650:   minutes = (sec_left) /60;
                   1651:   sec_left = (sec_left) % (60);
                   1652:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1653:   return ascdiff;
                   1654: }
                   1655: 
1.126     brouard  1656: /***************** f1dim *************************/
                   1657: extern int ncom; 
                   1658: extern double *pcom,*xicom;
                   1659: extern double (*nrfunc)(double []); 
                   1660:  
                   1661: double f1dim(double x) 
                   1662: { 
                   1663:   int j; 
                   1664:   double f;
                   1665:   double *xt; 
                   1666:  
                   1667:   xt=vector(1,ncom); 
                   1668:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1669:   f=(*nrfunc)(xt); 
                   1670:   free_vector(xt,1,ncom); 
                   1671:   return f; 
                   1672: } 
                   1673: 
                   1674: /*****************brent *************************/
                   1675: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1676: {
                   1677:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1678:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1679:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1680:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1681:    * returned function value. 
                   1682:   */
1.126     brouard  1683:   int iter; 
                   1684:   double a,b,d,etemp;
1.159     brouard  1685:   double fu=0,fv,fw,fx;
1.164     brouard  1686:   double ftemp=0.;
1.126     brouard  1687:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1688:   double e=0.0; 
                   1689:  
                   1690:   a=(ax < cx ? ax : cx); 
                   1691:   b=(ax > cx ? ax : cx); 
                   1692:   x=w=v=bx; 
                   1693:   fw=fv=fx=(*f)(x); 
                   1694:   for (iter=1;iter<=ITMAX;iter++) { 
                   1695:     xm=0.5*(a+b); 
                   1696:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1697:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1698:     printf(".");fflush(stdout);
                   1699:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1700: #ifdef DEBUGBRENT
1.126     brouard  1701:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1702:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1703:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1704: #endif
                   1705:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1706:       *xmin=x; 
                   1707:       return fx; 
                   1708:     } 
                   1709:     ftemp=fu;
                   1710:     if (fabs(e) > tol1) { 
                   1711:       r=(x-w)*(fx-fv); 
                   1712:       q=(x-v)*(fx-fw); 
                   1713:       p=(x-v)*q-(x-w)*r; 
                   1714:       q=2.0*(q-r); 
                   1715:       if (q > 0.0) p = -p; 
                   1716:       q=fabs(q); 
                   1717:       etemp=e; 
                   1718:       e=d; 
                   1719:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1720:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1721:       else { 
1.224     brouard  1722:                                d=p/q; 
                   1723:                                u=x+d; 
                   1724:                                if (u-a < tol2 || b-u < tol2) 
                   1725:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1726:       } 
                   1727:     } else { 
                   1728:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1729:     } 
                   1730:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1731:     fu=(*f)(u); 
                   1732:     if (fu <= fx) { 
                   1733:       if (u >= x) a=x; else b=x; 
                   1734:       SHFT(v,w,x,u) 
1.183     brouard  1735:       SHFT(fv,fw,fx,fu) 
                   1736:     } else { 
                   1737:       if (u < x) a=u; else b=u; 
                   1738:       if (fu <= fw || w == x) { 
1.224     brouard  1739:                                v=w; 
                   1740:                                w=u; 
                   1741:                                fv=fw; 
                   1742:                                fw=fu; 
1.183     brouard  1743:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1744:                                v=u; 
                   1745:                                fv=fu; 
1.183     brouard  1746:       } 
                   1747:     } 
1.126     brouard  1748:   } 
                   1749:   nrerror("Too many iterations in brent"); 
                   1750:   *xmin=x; 
                   1751:   return fx; 
                   1752: } 
                   1753: 
                   1754: /****************** mnbrak ***********************/
                   1755: 
                   1756: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1757:            double (*func)(double)) 
1.183     brouard  1758: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1759: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1760: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1761: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1762:    */
1.126     brouard  1763:   double ulim,u,r,q, dum;
                   1764:   double fu; 
1.187     brouard  1765: 
                   1766:   double scale=10.;
                   1767:   int iterscale=0;
                   1768: 
                   1769:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1770:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1771: 
                   1772: 
                   1773:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1774:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1775:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1776:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1777:   /* } */
                   1778: 
1.126     brouard  1779:   if (*fb > *fa) { 
                   1780:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1781:     SHFT(dum,*fb,*fa,dum) 
                   1782:   } 
1.126     brouard  1783:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1784:   *fc=(*func)(*cx); 
1.183     brouard  1785: #ifdef DEBUG
1.224     brouard  1786:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1787:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1788: #endif
1.224     brouard  1789:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1790:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1791:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1792:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1793:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1794:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1795:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1796:       fu=(*func)(u); 
1.163     brouard  1797: #ifdef DEBUG
                   1798:       /* f(x)=A(x-u)**2+f(u) */
                   1799:       double A, fparabu; 
                   1800:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1801:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1802:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1803:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1804:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1805:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1806:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1807:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1808: #endif 
1.184     brouard  1809: #ifdef MNBRAKORIGINAL
1.183     brouard  1810: #else
1.191     brouard  1811: /*       if (fu > *fc) { */
                   1812: /* #ifdef DEBUG */
                   1813: /*       printf("mnbrak4  fu > fc \n"); */
                   1814: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1815: /* #endif */
                   1816: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1817: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1818: /*     dum=u; /\* Shifting c and u *\/ */
                   1819: /*     u = *cx; */
                   1820: /*     *cx = dum; */
                   1821: /*     dum = fu; */
                   1822: /*     fu = *fc; */
                   1823: /*     *fc =dum; */
                   1824: /*       } else { /\* end *\/ */
                   1825: /* #ifdef DEBUG */
                   1826: /*       printf("mnbrak3  fu < fc \n"); */
                   1827: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1828: /* #endif */
                   1829: /*     dum=u; /\* Shifting c and u *\/ */
                   1830: /*     u = *cx; */
                   1831: /*     *cx = dum; */
                   1832: /*     dum = fu; */
                   1833: /*     fu = *fc; */
                   1834: /*     *fc =dum; */
                   1835: /*       } */
1.224     brouard  1836: #ifdef DEBUGMNBRAK
                   1837:                 double A, fparabu; 
                   1838:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1839:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1840:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1841:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1842: #endif
1.191     brouard  1843:       dum=u; /* Shifting c and u */
                   1844:       u = *cx;
                   1845:       *cx = dum;
                   1846:       dum = fu;
                   1847:       fu = *fc;
                   1848:       *fc =dum;
1.183     brouard  1849: #endif
1.162     brouard  1850:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1851: #ifdef DEBUG
1.224     brouard  1852:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1853:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1854: #endif
1.126     brouard  1855:       fu=(*func)(u); 
                   1856:       if (fu < *fc) { 
1.183     brouard  1857: #ifdef DEBUG
1.224     brouard  1858:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1859:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1860: #endif
                   1861:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1862:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1863: #ifdef DEBUG
                   1864:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1865: #endif
                   1866:       } 
1.162     brouard  1867:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1868: #ifdef DEBUG
1.224     brouard  1869:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1870:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1871: #endif
1.126     brouard  1872:       u=ulim; 
                   1873:       fu=(*func)(u); 
1.183     brouard  1874:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1875: #ifdef DEBUG
1.224     brouard  1876:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1877:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1878: #endif
1.126     brouard  1879:       u=(*cx)+GOLD*(*cx-*bx); 
                   1880:       fu=(*func)(u); 
1.224     brouard  1881: #ifdef DEBUG
                   1882:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1883:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1884: #endif
1.183     brouard  1885:     } /* end tests */
1.126     brouard  1886:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1887:     SHFT(*fa,*fb,*fc,fu) 
                   1888: #ifdef DEBUG
1.224     brouard  1889:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1890:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1891: #endif
                   1892:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1893: } 
                   1894: 
                   1895: /*************** linmin ************************/
1.162     brouard  1896: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1897: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1898: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1899: the value of func at the returned location p . This is actually all accomplished by calling the
                   1900: routines mnbrak and brent .*/
1.126     brouard  1901: int ncom; 
                   1902: double *pcom,*xicom;
                   1903: double (*nrfunc)(double []); 
                   1904:  
1.224     brouard  1905: #ifdef LINMINORIGINAL
1.126     brouard  1906: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1907: #else
                   1908: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1909: #endif
1.126     brouard  1910: { 
                   1911:   double brent(double ax, double bx, double cx, 
                   1912:               double (*f)(double), double tol, double *xmin); 
                   1913:   double f1dim(double x); 
                   1914:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1915:              double *fc, double (*func)(double)); 
                   1916:   int j; 
                   1917:   double xx,xmin,bx,ax; 
                   1918:   double fx,fb,fa;
1.187     brouard  1919: 
1.203     brouard  1920: #ifdef LINMINORIGINAL
                   1921: #else
                   1922:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1923: #endif
                   1924:   
1.126     brouard  1925:   ncom=n; 
                   1926:   pcom=vector(1,n); 
                   1927:   xicom=vector(1,n); 
                   1928:   nrfunc=func; 
                   1929:   for (j=1;j<=n;j++) { 
                   1930:     pcom[j]=p[j]; 
1.202     brouard  1931:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1932:   } 
1.187     brouard  1933: 
1.203     brouard  1934: #ifdef LINMINORIGINAL
                   1935:   xx=1.;
                   1936: #else
                   1937:   axs=0.0;
                   1938:   xxs=1.;
                   1939:   do{
                   1940:     xx= xxs;
                   1941: #endif
1.187     brouard  1942:     ax=0.;
                   1943:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   1944:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   1945:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   1946:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   1947:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   1948:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   1949:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  1950: #ifdef LINMINORIGINAL
                   1951: #else
                   1952:     if (fx != fx){
1.224     brouard  1953:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   1954:                        printf("|");
                   1955:                        fprintf(ficlog,"|");
1.203     brouard  1956: #ifdef DEBUGLINMIN
1.224     brouard  1957:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  1958: #endif
                   1959:     }
1.224     brouard  1960:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  1961: #endif
                   1962:   
1.191     brouard  1963: #ifdef DEBUGLINMIN
                   1964:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  1965:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  1966: #endif
1.224     brouard  1967: #ifdef LINMINORIGINAL
                   1968: #else
                   1969:        if(fb == fx){ /* Flat function in the direction */
                   1970:                xmin=xx;
                   1971:     *flat=1;
                   1972:        }else{
                   1973:     *flat=0;
                   1974: #endif
                   1975:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  1976:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   1977:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   1978:   /* fmin = f(p[j] + xmin * xi[j]) */
                   1979:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   1980:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  1981: #ifdef DEBUG
1.224     brouard  1982:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   1983:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   1984: #endif
                   1985: #ifdef LINMINORIGINAL
                   1986: #else
                   1987:                        }
1.126     brouard  1988: #endif
1.191     brouard  1989: #ifdef DEBUGLINMIN
                   1990:   printf("linmin end ");
1.202     brouard  1991:   fprintf(ficlog,"linmin end ");
1.191     brouard  1992: #endif
1.126     brouard  1993:   for (j=1;j<=n;j++) { 
1.203     brouard  1994: #ifdef LINMINORIGINAL
                   1995:     xi[j] *= xmin; 
                   1996: #else
                   1997: #ifdef DEBUGLINMIN
                   1998:     if(xxs <1.0)
                   1999:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2000: #endif
                   2001:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2002: #ifdef DEBUGLINMIN
                   2003:     if(xxs <1.0)
                   2004:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2005: #endif
                   2006: #endif
1.187     brouard  2007:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2008:   } 
1.191     brouard  2009: #ifdef DEBUGLINMIN
1.203     brouard  2010:   printf("\n");
1.191     brouard  2011:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2012:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2013:   for (j=1;j<=n;j++) { 
1.202     brouard  2014:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2015:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2016:     if(j % ncovmodel == 0){
1.191     brouard  2017:       printf("\n");
1.202     brouard  2018:       fprintf(ficlog,"\n");
                   2019:     }
1.191     brouard  2020:   }
1.203     brouard  2021: #else
1.191     brouard  2022: #endif
1.126     brouard  2023:   free_vector(xicom,1,n); 
                   2024:   free_vector(pcom,1,n); 
                   2025: } 
                   2026: 
                   2027: 
                   2028: /*************** powell ************************/
1.162     brouard  2029: /*
                   2030: Minimization of a function func of n variables. Input consists of an initial starting point
                   2031: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2032: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2033: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2034: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2035: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2036:  */
1.224     brouard  2037: #ifdef LINMINORIGINAL
                   2038: #else
                   2039:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2040:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2041: #endif
1.126     brouard  2042: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2043:            double (*func)(double [])) 
                   2044: { 
1.224     brouard  2045: #ifdef LINMINORIGINAL
                   2046:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2047:              double (*func)(double [])); 
1.224     brouard  2048: #else 
                   2049:  void linmin(double p[], double xi[], int n, double *fret, 
                   2050:                                                 double (*func)(double []),int *flat); 
                   2051: #endif
1.126     brouard  2052:   int i,ibig,j; 
                   2053:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2054:   double directest;
1.126     brouard  2055:   double fp,fptt;
                   2056:   double *xits;
                   2057:   int niterf, itmp;
1.224     brouard  2058: #ifdef LINMINORIGINAL
                   2059: #else
                   2060: 
                   2061:   flatdir=ivector(1,n); 
                   2062:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2063: #endif
1.126     brouard  2064: 
                   2065:   pt=vector(1,n); 
                   2066:   ptt=vector(1,n); 
                   2067:   xit=vector(1,n); 
                   2068:   xits=vector(1,n); 
                   2069:   *fret=(*func)(p); 
                   2070:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2071:   rcurr_time = time(NULL);  
1.126     brouard  2072:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2073:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2074:     ibig=0; 
                   2075:     del=0.0; 
1.157     brouard  2076:     rlast_time=rcurr_time;
                   2077:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2078:     rcurr_time = time(NULL);  
                   2079:     curr_time = *localtime(&rcurr_time);
                   2080:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2081:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2082: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2083:     for (i=1;i<=n;i++) {
1.126     brouard  2084:       printf(" %d %.12f",i, p[i]);
                   2085:       fprintf(ficlog," %d %.12lf",i, p[i]);
                   2086:       fprintf(ficrespow," %.12lf", p[i]);
                   2087:     }
                   2088:     printf("\n");
                   2089:     fprintf(ficlog,"\n");
                   2090:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2091:     if(*iter <=3){
1.157     brouard  2092:       tml = *localtime(&rcurr_time);
                   2093:       strcpy(strcurr,asctime(&tml));
                   2094:       rforecast_time=rcurr_time; 
1.126     brouard  2095:       itmp = strlen(strcurr);
                   2096:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.224     brouard  2097:                                strcurr[itmp-1]='\0';
1.162     brouard  2098:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2099:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2100:       for(niterf=10;niterf<=30;niterf+=10){
1.224     brouard  2101:                                rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2102:                                forecast_time = *localtime(&rforecast_time);
                   2103:                                strcpy(strfor,asctime(&forecast_time));
                   2104:                                itmp = strlen(strfor);
                   2105:                                if(strfor[itmp-1]=='\n')
                   2106:                                        strfor[itmp-1]='\0';
                   2107:                                printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2108:                                fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2109:       }
                   2110:     }
1.187     brouard  2111:     for (i=1;i<=n;i++) { /* For each direction i */
                   2112:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2113:       fptt=(*fret); 
                   2114: #ifdef DEBUG
1.203     brouard  2115:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2116:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2117: #endif
1.203     brouard  2118:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2119:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2120: #ifdef LINMINORIGINAL
1.188     brouard  2121:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2122: #else
                   2123:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2124:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2125: #endif
                   2126:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2127:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2128:                                /* because that direction will be replaced unless the gain del is small */
                   2129:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2130:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2131:                                /* with the new direction. */
                   2132:                                del=fabs(fptt-(*fret)); 
                   2133:                                ibig=i; 
1.126     brouard  2134:       } 
                   2135: #ifdef DEBUG
                   2136:       printf("%d %.12e",i,(*fret));
                   2137:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2138:       for (j=1;j<=n;j++) {
1.224     brouard  2139:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2140:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2141:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2142:       }
                   2143:       for(j=1;j<=n;j++) {
1.225     brouard  2144:                                printf(" p(%d)=%.12e",j,p[j]);
                   2145:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2146:       }
                   2147:       printf("\n");
                   2148:       fprintf(ficlog,"\n");
                   2149: #endif
1.187     brouard  2150:     } /* end loop on each direction i */
                   2151:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2152:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2153:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2154:       for(j=1;j<=n;j++) {
1.225     brouard  2155:                                if(flatdir[j] >0){
                   2156:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2157:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2158:                                }
                   2159:                                /* printf("\n"); */
                   2160:                                /* fprintf(ficlog,"\n"); */
                   2161:                        }
1.182     brouard  2162:     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /* Did we reach enough precision? */
1.188     brouard  2163:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2164:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2165:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2166:       /* decreased of more than 3.84  */
                   2167:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2168:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2169:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2170:                        
1.188     brouard  2171:       /* Starting the program with initial values given by a former maximization will simply change */
                   2172:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2173:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2174:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2175: #ifdef DEBUG
                   2176:       int k[2],l;
                   2177:       k[0]=1;
                   2178:       k[1]=-1;
                   2179:       printf("Max: %.12e",(*func)(p));
                   2180:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2181:       for (j=1;j<=n;j++) {
                   2182:        printf(" %.12e",p[j]);
                   2183:        fprintf(ficlog," %.12e",p[j]);
                   2184:       }
                   2185:       printf("\n");
                   2186:       fprintf(ficlog,"\n");
                   2187:       for(l=0;l<=1;l++) {
                   2188:        for (j=1;j<=n;j++) {
                   2189:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2190:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2191:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2192:        }
                   2193:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2194:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2195:       }
                   2196: #endif
                   2197: 
1.224     brouard  2198: #ifdef LINMINORIGINAL
                   2199: #else
                   2200:       free_ivector(flatdir,1,n); 
                   2201: #endif
1.126     brouard  2202:       free_vector(xit,1,n); 
                   2203:       free_vector(xits,1,n); 
                   2204:       free_vector(ptt,1,n); 
                   2205:       free_vector(pt,1,n); 
                   2206:       return; 
1.192     brouard  2207:     } /* enough precision */ 
1.126     brouard  2208:     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2209:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2210:       ptt[j]=2.0*p[j]-pt[j]; 
                   2211:       xit[j]=p[j]-pt[j]; 
                   2212:       pt[j]=p[j]; 
                   2213:     } 
1.181     brouard  2214:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2215: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2216:                if (*iter <=4) {
1.225     brouard  2217: #else
                   2218: #endif
1.224     brouard  2219: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2220: #else
1.161     brouard  2221:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2222: #endif
1.162     brouard  2223:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2224:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2225:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2226:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2227:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2228:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2229:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2230:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2231:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2232:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2233:       /* mu² and del² are equal when f3=f1 */
                   2234:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2235:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2236:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2237:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2238: #ifdef NRCORIGINAL
                   2239:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2240: #else
                   2241:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2242:       t= t- del*SQR(fp-fptt);
1.183     brouard  2243: #endif
1.202     brouard  2244:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2245: #ifdef DEBUG
1.181     brouard  2246:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2247:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2248:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2249:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2250:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2251:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2252:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2253:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2254: #endif
1.183     brouard  2255: #ifdef POWELLORIGINAL
                   2256:       if (t < 0.0) { /* Then we use it for new direction */
                   2257: #else
1.182     brouard  2258:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2259:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2260:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2261:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2262:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2263:       } 
1.181     brouard  2264:       if (directest < 0.0) { /* Then we use it for new direction */
                   2265: #endif
1.191     brouard  2266: #ifdef DEBUGLINMIN
1.234     brouard  2267:        printf("Before linmin in direction P%d-P0\n",n);
                   2268:        for (j=1;j<=n;j++) {
                   2269:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2270:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2271:          if(j % ncovmodel == 0){
                   2272:            printf("\n");
                   2273:            fprintf(ficlog,"\n");
                   2274:          }
                   2275:        }
1.224     brouard  2276: #endif
                   2277: #ifdef LINMINORIGINAL
1.234     brouard  2278:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2279: #else
1.234     brouard  2280:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2281:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2282: #endif
1.234     brouard  2283:        
1.191     brouard  2284: #ifdef DEBUGLINMIN
1.234     brouard  2285:        for (j=1;j<=n;j++) { 
                   2286:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2287:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2288:          if(j % ncovmodel == 0){
                   2289:            printf("\n");
                   2290:            fprintf(ficlog,"\n");
                   2291:          }
                   2292:        }
1.224     brouard  2293: #endif
1.234     brouard  2294:        for (j=1;j<=n;j++) { 
                   2295:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2296:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2297:        }
1.224     brouard  2298: #ifdef LINMINORIGINAL
                   2299: #else
1.234     brouard  2300:        for (j=1, flatd=0;j<=n;j++) {
                   2301:          if(flatdir[j]>0)
                   2302:            flatd++;
                   2303:        }
                   2304:        if(flatd >0){
                   2305:          printf("%d flat directions\n",flatd);
                   2306:          fprintf(ficlog,"%d flat directions\n",flatd);
                   2307:          for (j=1;j<=n;j++) { 
                   2308:            if(flatdir[j]>0){
                   2309:              printf("%d ",j);
                   2310:              fprintf(ficlog,"%d ",j);
                   2311:            }
                   2312:          }
                   2313:          printf("\n");
                   2314:          fprintf(ficlog,"\n");
                   2315:        }
1.191     brouard  2316: #endif
1.234     brouard  2317:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2318:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2319:        
1.126     brouard  2320: #ifdef DEBUG
1.234     brouard  2321:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2322:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2323:        for(j=1;j<=n;j++){
                   2324:          printf(" %lf",xit[j]);
                   2325:          fprintf(ficlog," %lf",xit[j]);
                   2326:        }
                   2327:        printf("\n");
                   2328:        fprintf(ficlog,"\n");
1.126     brouard  2329: #endif
1.192     brouard  2330:       } /* end of t or directest negative */
1.224     brouard  2331: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2332: #else
1.234     brouard  2333:       } /* end if (fptt < fp)  */
1.192     brouard  2334: #endif
1.225     brouard  2335: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2336:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2337: #else
1.224     brouard  2338: #endif
1.234     brouard  2339:                } /* loop iteration */ 
1.126     brouard  2340: } 
1.234     brouard  2341:   
1.126     brouard  2342: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2343:   
1.235   ! brouard  2344:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2345:   {
1.235   ! brouard  2346:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
        !          2347:        (and selected quantitative values in nres)
        !          2348:        by left multiplying the unit
1.234     brouard  2349:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2350:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2351:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2352:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2353:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2354:   /* Initial matrix pimij */
                   2355:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2356:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2357:   /*  0,                   0                  , 1} */
                   2358:   /*
                   2359:    * and after some iteration: */
                   2360:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2361:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2362:   /*  0,                   0                  , 1} */
                   2363:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2364:   /* {0.51571254859325999, 0.4842874514067399, */
                   2365:   /*  0.51326036147820708, 0.48673963852179264} */
                   2366:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2367:     
1.126     brouard  2368:   int i, ii,j,k;
1.209     brouard  2369:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2370:   /* double **matprod2(); */ /* test */
1.218     brouard  2371:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2372:   double **newm;
1.209     brouard  2373:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2374:   int ncvloop=0;
1.169     brouard  2375:   
1.209     brouard  2376:   min=vector(1,nlstate);
                   2377:   max=vector(1,nlstate);
                   2378:   meandiff=vector(1,nlstate);
                   2379: 
1.218     brouard  2380:        /* Starting with matrix unity */
1.126     brouard  2381:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2382:     for (j=1;j<=nlstate+ndeath;j++){
                   2383:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2384:     }
1.169     brouard  2385:   
                   2386:   cov[1]=1.;
                   2387:   
                   2388:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2389:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2390:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2391:     ncvloop++;
1.126     brouard  2392:     newm=savm;
                   2393:     /* Covariates have to be included here again */
1.138     brouard  2394:     cov[2]=agefin;
1.187     brouard  2395:     if(nagesqr==1)
                   2396:       cov[3]= agefin*agefin;;
1.234     brouard  2397:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2398:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2399:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235   ! brouard  2400:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2401:     }
                   2402:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2403:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235   ! brouard  2404:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
        !          2405:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2406:     }
1.234     brouard  2407:     for (k=1; k<=cptcovage;k++){
                   2408:       if(Dummy[Tvar[Tage[k]]]){
                   2409:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2410:       } else{
1.235   ! brouard  2411:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2412:       }
1.235   ! brouard  2413:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2414:     }
                   2415:     for (k=1; k<=cptcovprod;k++){ /*  */
1.235   ! brouard  2416:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.200     brouard  2417:       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
1.234     brouard  2418:     }
1.138     brouard  2419:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2420:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2421:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2422:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2423:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2424:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2425:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2426:     
1.126     brouard  2427:     savm=oldm;
                   2428:     oldm=newm;
1.209     brouard  2429: 
                   2430:     for(j=1; j<=nlstate; j++){
                   2431:       max[j]=0.;
                   2432:       min[j]=1.;
                   2433:     }
                   2434:     for(i=1;i<=nlstate;i++){
                   2435:       sumnew=0;
                   2436:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2437:       for(j=1; j<=nlstate; j++){ 
                   2438:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2439:        max[j]=FMAX(max[j],prlim[i][j]);
                   2440:        min[j]=FMIN(min[j],prlim[i][j]);
                   2441:       }
                   2442:     }
                   2443: 
1.126     brouard  2444:     maxmax=0.;
1.209     brouard  2445:     for(j=1; j<=nlstate; j++){
                   2446:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2447:       maxmax=FMAX(maxmax,meandiff[j]);
                   2448:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2449:     } /* j loop */
1.203     brouard  2450:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2451:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2452:     if(maxmax < ftolpl){
1.209     brouard  2453:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2454:       free_vector(min,1,nlstate);
                   2455:       free_vector(max,1,nlstate);
                   2456:       free_vector(meandiff,1,nlstate);
1.126     brouard  2457:       return prlim;
                   2458:     }
1.169     brouard  2459:   } /* age loop */
1.208     brouard  2460:     /* After some age loop it doesn't converge */
1.209     brouard  2461:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2462: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2463:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2464:   free_vector(min,1,nlstate);
                   2465:   free_vector(max,1,nlstate);
                   2466:   free_vector(meandiff,1,nlstate);
1.208     brouard  2467:   
1.169     brouard  2468:   return prlim; /* should not reach here */
1.126     brouard  2469: }
                   2470: 
1.217     brouard  2471: 
                   2472:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2473: 
1.218     brouard  2474:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2475:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2476:  double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij)
1.217     brouard  2477: {
1.218     brouard  2478:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2479:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2480:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2481:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2482:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2483:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2484:   /* Initial matrix pimij */
                   2485:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2486:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2487:   /*  0,                   0                  , 1} */
                   2488:   /*
                   2489:    * and after some iteration: */
                   2490:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2491:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2492:   /*  0,                   0                  , 1} */
                   2493:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2494:   /* {0.51571254859325999, 0.4842874514067399, */
                   2495:   /*  0.51326036147820708, 0.48673963852179264} */
                   2496:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2497: 
                   2498:   int i, ii,j,k;
                   2499:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2500:   /* double **matprod2(); */ /* test */
                   2501:   double **out, cov[NCOVMAX+1], **bmij();
                   2502:   double **newm;
1.218     brouard  2503:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2504:   double        **oldm, **savm;  /* for use */
                   2505: 
1.217     brouard  2506:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2507:   int ncvloop=0;
                   2508:   
                   2509:   min=vector(1,nlstate);
                   2510:   max=vector(1,nlstate);
                   2511:   meandiff=vector(1,nlstate);
                   2512: 
1.218     brouard  2513:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2514:        oldm=oldms; savm=savms;
                   2515: 
                   2516:        /* Starting with matrix unity */
                   2517:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2518:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2519:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2520:     }
                   2521:   
                   2522:   cov[1]=1.;
                   2523:   
                   2524:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2525:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2526:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2527:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2528:     ncvloop++;
1.218     brouard  2529:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2530:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2531:     /* Covariates have to be included here again */
                   2532:     cov[2]=agefin;
                   2533:     if(nagesqr==1)
                   2534:       cov[3]= agefin*agefin;;
                   2535:     for (k=1; k<=cptcovn;k++) {
                   2536:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
                   2537:       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   2538:       /* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); */
                   2539:     }
                   2540:     for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2];
                   2541:     for (k=1; k<=cptcovprod;k++) /* Useless */
                   2542:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
                   2543:       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2544:     
                   2545:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2546:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2547:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2548:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2549:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2550:                /* ij should be linked to the correct index of cov */
                   2551:                /* age and covariate values ij are in 'cov', but we need to pass
                   2552:                 * ij for the observed prevalence at age and status and covariate
                   2553:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2554:                 */
                   2555:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2556:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2557:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2558:     savm=oldm;
                   2559:     oldm=newm;
                   2560:     for(j=1; j<=nlstate; j++){
                   2561:       max[j]=0.;
                   2562:       min[j]=1.;
                   2563:     }
                   2564:     for(j=1; j<=nlstate; j++){ 
                   2565:       for(i=1;i<=nlstate;i++){
1.234     brouard  2566:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2567:        bprlim[i][j]= newm[i][j];
                   2568:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2569:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2570:       }
                   2571:     }
1.218     brouard  2572:                
1.217     brouard  2573:     maxmax=0.;
                   2574:     for(i=1; i<=nlstate; i++){
                   2575:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2576:       maxmax=FMAX(maxmax,meandiff[i]);
                   2577:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2578:     } /* j loop */
                   2579:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2580:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2581:     if(maxmax < ftolpl){
1.220     brouard  2582:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2583:       free_vector(min,1,nlstate);
                   2584:       free_vector(max,1,nlstate);
                   2585:       free_vector(meandiff,1,nlstate);
                   2586:       return bprlim;
                   2587:     }
                   2588:   } /* age loop */
                   2589:     /* After some age loop it doesn't converge */
                   2590:   printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
                   2591: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2592:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2593:   free_vector(min,1,nlstate);
                   2594:   free_vector(max,1,nlstate);
                   2595:   free_vector(meandiff,1,nlstate);
                   2596:   
                   2597:   return bprlim; /* should not reach here */
                   2598: }
                   2599: 
1.126     brouard  2600: /*************** transition probabilities ***************/ 
                   2601: 
                   2602: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2603: {
1.138     brouard  2604:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2605:      computes the probability to be observed in state j being in state i by appying the
                   2606:      model to the ncovmodel covariates (including constant and age).
                   2607:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2608:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2609:      ncth covariate in the global vector x is given by the formula:
                   2610:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2611:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2612:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2613:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2614:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2615:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2616:   */
                   2617:   double s1, lnpijopii;
1.126     brouard  2618:   /*double t34;*/
1.164     brouard  2619:   int i,j, nc, ii, jj;
1.126     brouard  2620: 
1.223     brouard  2621:   for(i=1; i<= nlstate; i++){
                   2622:     for(j=1; j<i;j++){
                   2623:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2624:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2625:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2626:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2627:       }
                   2628:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2629:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2630:     }
                   2631:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2632:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2633:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2634:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2635:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2636:       }
                   2637:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2638:     }
                   2639:   }
1.218     brouard  2640:   
1.223     brouard  2641:   for(i=1; i<= nlstate; i++){
                   2642:     s1=0;
                   2643:     for(j=1; j<i; j++){
                   2644:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2645:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2646:     }
                   2647:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2648:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2649:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2650:     }
                   2651:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2652:     ps[i][i]=1./(s1+1.);
                   2653:     /* Computing other pijs */
                   2654:     for(j=1; j<i; j++)
                   2655:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2656:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2657:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2658:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2659:   } /* end i */
1.218     brouard  2660:   
1.223     brouard  2661:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2662:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2663:       ps[ii][jj]=0;
                   2664:       ps[ii][ii]=1;
                   2665:     }
                   2666:   }
1.218     brouard  2667:   
                   2668:   
1.223     brouard  2669:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2670:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2671:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2672:   /*   } */
                   2673:   /*   printf("\n "); */
                   2674:   /* } */
                   2675:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2676:   /*
                   2677:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2678:                goto end;*/
1.223     brouard  2679:   return ps;
1.126     brouard  2680: }
                   2681: 
1.218     brouard  2682: /*************** backward transition probabilities ***************/ 
                   2683: 
                   2684:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2685: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2686:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2687: {
1.222     brouard  2688:   /* Computes the backward probability at age agefin and covariate ij
                   2689:    * and returns in **ps as well as **bmij.
                   2690:    */
1.218     brouard  2691:   int i, ii, j,k;
1.222     brouard  2692:   
                   2693:   double **out, **pmij();
                   2694:   double sumnew=0.;
1.218     brouard  2695:   double agefin;
1.222     brouard  2696:   
                   2697:   double **dnewm, **dsavm, **doldm;
                   2698:   double **bbmij;
                   2699:   
1.218     brouard  2700:   doldm=ddoldms; /* global pointers */
1.222     brouard  2701:   dnewm=ddnewms;
                   2702:   dsavm=ddsavms;
                   2703:   
                   2704:   agefin=cov[2];
                   2705:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2706:      the observed prevalence (with this covariate ij) */
                   2707:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2708:   /* We do have the matrix Px in savm  and we need pij */
                   2709:   for (j=1;j<=nlstate+ndeath;j++){
                   2710:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2711:     for (ii=1;ii<=nlstate;ii++){
                   2712:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2713:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2714:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2715:       if(sumnew >= 1.e-10){
                   2716:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2717:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2718:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2719:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2720:        /* }else */
                   2721:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2722:       }else{
                   2723:        printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin);
                   2724:       }
                   2725:     } /*End ii */
                   2726:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2727:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2728:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2729:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2730:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2731:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2732:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2733:   for (j=1;j<=nlstate+ndeath;j++){
                   2734:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2735:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2736:     }
                   2737:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2738:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2739:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2740:   /* end bmij */
                   2741:   return ps; 
1.218     brouard  2742: }
1.217     brouard  2743: /*************** transition probabilities ***************/ 
                   2744: 
1.218     brouard  2745: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2746: {
                   2747:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2748:      computes the probability to be observed in state j being in state i by appying the
                   2749:      model to the ncovmodel covariates (including constant and age).
                   2750:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2751:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2752:      ncth covariate in the global vector x is given by the formula:
                   2753:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2754:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2755:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2756:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2757:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2758:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2759:   */
                   2760:   double s1, lnpijopii;
                   2761:   /*double t34;*/
                   2762:   int i,j, nc, ii, jj;
                   2763: 
1.234     brouard  2764:   for(i=1; i<= nlstate; i++){
                   2765:     for(j=1; j<i;j++){
                   2766:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2767:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2768:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2769:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2770:       }
                   2771:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2772:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2773:     }
                   2774:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2775:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2776:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2777:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2778:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2779:       }
                   2780:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2781:     }
                   2782:   }
                   2783:   
                   2784:   for(i=1; i<= nlstate; i++){
                   2785:     s1=0;
                   2786:     for(j=1; j<i; j++){
                   2787:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2788:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2789:     }
                   2790:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2791:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2792:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2793:     }
                   2794:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2795:     ps[i][i]=1./(s1+1.);
                   2796:     /* Computing other pijs */
                   2797:     for(j=1; j<i; j++)
                   2798:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2799:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2800:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2801:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2802:   } /* end i */
                   2803:   
                   2804:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2805:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2806:       ps[ii][jj]=0;
                   2807:       ps[ii][ii]=1;
                   2808:     }
                   2809:   }
                   2810:   /* Added for backcast */ /* Transposed matrix too */
                   2811:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2812:     s1=0.;
                   2813:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2814:       s1+=ps[ii][jj];
                   2815:     }
                   2816:     for(ii=1; ii<= nlstate; ii++){
                   2817:       ps[ii][jj]=ps[ii][jj]/s1;
                   2818:     }
                   2819:   }
                   2820:   /* Transposition */
                   2821:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2822:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2823:       s1=ps[ii][jj];
                   2824:       ps[ii][jj]=ps[jj][ii];
                   2825:       ps[jj][ii]=s1;
                   2826:     }
                   2827:   }
                   2828:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2829:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2830:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2831:   /*   } */
                   2832:   /*   printf("\n "); */
                   2833:   /* } */
                   2834:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2835:   /*
                   2836:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2837:     goto end;*/
                   2838:   return ps;
1.217     brouard  2839: }
                   2840: 
                   2841: 
1.126     brouard  2842: /**************** Product of 2 matrices ******************/
                   2843: 
1.145     brouard  2844: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2845: {
                   2846:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2847:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2848:   /* in, b, out are matrice of pointers which should have been initialized 
                   2849:      before: only the contents of out is modified. The function returns
                   2850:      a pointer to pointers identical to out */
1.145     brouard  2851:   int i, j, k;
1.126     brouard  2852:   for(i=nrl; i<= nrh; i++)
1.145     brouard  2853:     for(k=ncolol; k<=ncoloh; k++){
                   2854:       out[i][k]=0.;
                   2855:       for(j=ncl; j<=nch; j++)
                   2856:        out[i][k] +=in[i][j]*b[j][k];
                   2857:     }
1.126     brouard  2858:   return out;
                   2859: }
                   2860: 
                   2861: 
                   2862: /************* Higher Matrix Product ***************/
                   2863: 
1.235   ! brouard  2864: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  2865: {
1.218     brouard  2866:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  2867:      'nhstepm*hstepm*stepm' months (i.e. until
                   2868:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   2869:      nhstepm*hstepm matrices. 
                   2870:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   2871:      (typically every 2 years instead of every month which is too big 
                   2872:      for the memory).
                   2873:      Model is determined by parameters x and covariates have to be 
                   2874:      included manually here. 
                   2875: 
                   2876:      */
                   2877: 
                   2878:   int i, j, d, h, k;
1.131     brouard  2879:   double **out, cov[NCOVMAX+1];
1.126     brouard  2880:   double **newm;
1.187     brouard  2881:   double agexact;
1.214     brouard  2882:   double agebegin, ageend;
1.126     brouard  2883: 
                   2884:   /* Hstepm could be zero and should return the unit matrix */
                   2885:   for (i=1;i<=nlstate+ndeath;i++)
                   2886:     for (j=1;j<=nlstate+ndeath;j++){
                   2887:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   2888:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   2889:     }
                   2890:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2891:   for(h=1; h <=nhstepm; h++){
                   2892:     for(d=1; d <=hstepm; d++){
                   2893:       newm=savm;
                   2894:       /* Covariates have to be included here again */
                   2895:       cov[1]=1.;
1.214     brouard  2896:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  2897:       cov[2]=agexact;
                   2898:       if(nagesqr==1)
1.227     brouard  2899:        cov[3]= agexact*agexact;
1.235   ! brouard  2900:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
        !          2901:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
        !          2902:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
        !          2903:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
        !          2904:       }
        !          2905:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
        !          2906:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
        !          2907:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
        !          2908:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
        !          2909:       }
        !          2910:       for (k=1; k<=cptcovage;k++){
        !          2911:        if(Dummy[Tvar[Tage[k]]]){
        !          2912:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
        !          2913:        } else{
        !          2914:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
        !          2915:        }
        !          2916:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
        !          2917:       }
        !          2918:       for (k=1; k<=cptcovprod;k++){ /*  */
        !          2919:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
        !          2920:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
        !          2921:       }
        !          2922:       /* for (k=1; k<=cptcovn;k++)  */
        !          2923:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
        !          2924:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
        !          2925:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
        !          2926:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
        !          2927:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  2928:       
                   2929:       
1.126     brouard  2930:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   2931:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  2932:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  2933:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   2934:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  2935:       /* if((int)age == 70){ */
                   2936:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   2937:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   2938:       /*         printf("%d pmmij ",i); */
                   2939:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2940:       /*           printf("%f ",pmmij[i][j]); */
                   2941:       /*         } */
                   2942:       /*         printf(" oldm "); */
                   2943:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2944:       /*           printf("%f ",oldm[i][j]); */
                   2945:       /*         } */
                   2946:       /*         printf("\n"); */
                   2947:       /*       } */
                   2948:       /* } */
1.126     brouard  2949:       savm=oldm;
                   2950:       oldm=newm;
                   2951:     }
                   2952:     for(i=1; i<=nlstate+ndeath; i++)
                   2953:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  2954:                                po[i][j][h]=newm[i][j];
                   2955:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  2956:       }
1.128     brouard  2957:     /*printf("h=%d ",h);*/
1.126     brouard  2958:   } /* end h */
1.218     brouard  2959:        /*     printf("\n H=%d \n",h); */
1.126     brouard  2960:   return po;
                   2961: }
                   2962: 
1.217     brouard  2963: /************* Higher Back Matrix Product ***************/
1.218     brouard  2964: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  2965: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  2966: {
1.218     brouard  2967:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  2968:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  2969:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   2970:      nhstepm*hstepm matrices.
                   2971:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   2972:      (typically every 2 years instead of every month which is too big
1.217     brouard  2973:      for the memory).
1.218     brouard  2974:      Model is determined by parameters x and covariates have to be
                   2975:      included manually here.
1.217     brouard  2976: 
1.222     brouard  2977:   */
1.217     brouard  2978: 
                   2979:   int i, j, d, h, k;
                   2980:   double **out, cov[NCOVMAX+1];
                   2981:   double **newm;
                   2982:   double agexact;
                   2983:   double agebegin, ageend;
1.222     brouard  2984:   double **oldm, **savm;
1.217     brouard  2985: 
1.222     brouard  2986:   oldm=oldms;savm=savms;
1.217     brouard  2987:   /* Hstepm could be zero and should return the unit matrix */
                   2988:   for (i=1;i<=nlstate+ndeath;i++)
                   2989:     for (j=1;j<=nlstate+ndeath;j++){
                   2990:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   2991:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   2992:     }
                   2993:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2994:   for(h=1; h <=nhstepm; h++){
                   2995:     for(d=1; d <=hstepm; d++){
                   2996:       newm=savm;
                   2997:       /* Covariates have to be included here again */
                   2998:       cov[1]=1.;
                   2999:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3000:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3001:       cov[2]=agexact;
                   3002:       if(nagesqr==1)
1.222     brouard  3003:        cov[3]= agexact*agexact;
1.218     brouard  3004:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3005:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3006:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3007:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3008:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3009:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3010:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3011:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3012:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3013:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3014:                        
                   3015:                        
1.217     brouard  3016:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3017:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3018:       /* Careful transposed matrix */
1.222     brouard  3019:       /* age is in cov[2] */
1.218     brouard  3020:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3021:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3022:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3023:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3024:       /* if((int)age == 70){ */
                   3025:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3026:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3027:       /*         printf("%d pmmij ",i); */
                   3028:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3029:       /*           printf("%f ",pmmij[i][j]); */
                   3030:       /*         } */
                   3031:       /*         printf(" oldm "); */
                   3032:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3033:       /*           printf("%f ",oldm[i][j]); */
                   3034:       /*         } */
                   3035:       /*         printf("\n"); */
                   3036:       /*       } */
                   3037:       /* } */
                   3038:       savm=oldm;
                   3039:       oldm=newm;
                   3040:     }
                   3041:     for(i=1; i<=nlstate+ndeath; i++)
                   3042:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3043:        po[i][j][h]=newm[i][j];
                   3044:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3045:       }
                   3046:     /*printf("h=%d ",h);*/
                   3047:   } /* end h */
1.222     brouard  3048:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3049:   return po;
                   3050: }
                   3051: 
                   3052: 
1.162     brouard  3053: #ifdef NLOPT
                   3054:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3055:   double fret;
                   3056:   double *xt;
                   3057:   int j;
                   3058:   myfunc_data *d2 = (myfunc_data *) pd;
                   3059: /* xt = (p1-1); */
                   3060:   xt=vector(1,n); 
                   3061:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3062: 
                   3063:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3064:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3065:   printf("Function = %.12lf ",fret);
                   3066:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3067:   printf("\n");
                   3068:  free_vector(xt,1,n);
                   3069:   return fret;
                   3070: }
                   3071: #endif
1.126     brouard  3072: 
                   3073: /*************** log-likelihood *************/
                   3074: double func( double *x)
                   3075: {
1.226     brouard  3076:   int i, ii, j, k, mi, d, kk;
                   3077:   int ioffset=0;
                   3078:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3079:   double **out;
                   3080:   double lli; /* Individual log likelihood */
                   3081:   int s1, s2;
1.228     brouard  3082:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3083:   double bbh, survp;
                   3084:   long ipmx;
                   3085:   double agexact;
                   3086:   /*extern weight */
                   3087:   /* We are differentiating ll according to initial status */
                   3088:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3089:   /*for(i=1;i<imx;i++) 
                   3090:     printf(" %d\n",s[4][i]);
                   3091:   */
1.162     brouard  3092: 
1.226     brouard  3093:   ++countcallfunc;
1.162     brouard  3094: 
1.226     brouard  3095:   cov[1]=1.;
1.126     brouard  3096: 
1.226     brouard  3097:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3098:   ioffset=0;
1.226     brouard  3099:   if(mle==1){
                   3100:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3101:       /* Computes the values of the ncovmodel covariates of the model
                   3102:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3103:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3104:         to be observed in j being in i according to the model.
                   3105:       */
                   3106:       ioffset=2+nagesqr+cptcovage;
1.233     brouard  3107:    /* Fixed */
1.234     brouard  3108:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3109:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3110:       }
1.226     brouard  3111:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3112:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3113:         has been calculated etc */
                   3114:       /* For an individual i, wav[i] gives the number of effective waves */
                   3115:       /* We compute the contribution to Likelihood of each effective transition
                   3116:         mw[mi][i] is real wave of the mi th effectve wave */
                   3117:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3118:         s2=s[mw[mi+1][i]][i];
                   3119:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3120:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3121:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3122:       */
                   3123:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3124:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
                   3125:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i];
                   3126:        }
                   3127:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3128:          for (j=1;j<=nlstate+ndeath;j++){
                   3129:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3130:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3131:          }
                   3132:        for(d=0; d<dh[mi][i]; d++){
                   3133:          newm=savm;
                   3134:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3135:          cov[2]=agexact;
                   3136:          if(nagesqr==1)
                   3137:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3138:          for (kk=1; kk<=cptcovage;kk++) {
                   3139:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
                   3140:          }
                   3141:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3142:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3143:          savm=oldm;
                   3144:          oldm=newm;
                   3145:        } /* end mult */
                   3146:        
                   3147:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3148:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3149:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3150:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3151:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3152:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3153:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3154:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3155:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3156:                                 * -stepm/2 to stepm/2 .
                   3157:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3158:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3159:                                 */
1.234     brouard  3160:        s1=s[mw[mi][i]][i];
                   3161:        s2=s[mw[mi+1][i]][i];
                   3162:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3163:        /* bias bh is positive if real duration
                   3164:         * is higher than the multiple of stepm and negative otherwise.
                   3165:         */
                   3166:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3167:        if( s2 > nlstate){ 
                   3168:          /* i.e. if s2 is a death state and if the date of death is known 
                   3169:             then the contribution to the likelihood is the probability to 
                   3170:             die between last step unit time and current  step unit time, 
                   3171:             which is also equal to probability to die before dh 
                   3172:             minus probability to die before dh-stepm . 
                   3173:             In version up to 0.92 likelihood was computed
                   3174:             as if date of death was unknown. Death was treated as any other
                   3175:             health state: the date of the interview describes the actual state
                   3176:             and not the date of a change in health state. The former idea was
                   3177:             to consider that at each interview the state was recorded
                   3178:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3179:             introduced the exact date of death then we should have modified
                   3180:             the contribution of an exact death to the likelihood. This new
                   3181:             contribution is smaller and very dependent of the step unit
                   3182:             stepm. It is no more the probability to die between last interview
                   3183:             and month of death but the probability to survive from last
                   3184:             interview up to one month before death multiplied by the
                   3185:             probability to die within a month. Thanks to Chris
                   3186:             Jackson for correcting this bug.  Former versions increased
                   3187:             mortality artificially. The bad side is that we add another loop
                   3188:             which slows down the processing. The difference can be up to 10%
                   3189:             lower mortality.
                   3190:          */
                   3191:          /* If, at the beginning of the maximization mostly, the
                   3192:             cumulative probability or probability to be dead is
                   3193:             constant (ie = 1) over time d, the difference is equal to
                   3194:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3195:             s1 at precedent wave, to be dead a month before current
                   3196:             wave is equal to probability, being at state s1 at
                   3197:             precedent wave, to be dead at mont of the current
                   3198:             wave. Then the observed probability (that this person died)
                   3199:             is null according to current estimated parameter. In fact,
                   3200:             it should be very low but not zero otherwise the log go to
                   3201:             infinity.
                   3202:          */
1.183     brouard  3203: /* #ifdef INFINITYORIGINAL */
                   3204: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3205: /* #else */
                   3206: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3207: /*         lli=log(mytinydouble); */
                   3208: /*       else */
                   3209: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3210: /* #endif */
1.226     brouard  3211:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3212:          
1.226     brouard  3213:        } else if  ( s2==-1 ) { /* alive */
                   3214:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3215:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3216:          /*survp += out[s1][j]; */
                   3217:          lli= log(survp);
                   3218:        }
                   3219:        else if  (s2==-4) { 
                   3220:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3221:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3222:          lli= log(survp); 
                   3223:        } 
                   3224:        else if  (s2==-5) { 
                   3225:          for (j=1,survp=0. ; j<=2; j++)  
                   3226:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3227:          lli= log(survp); 
                   3228:        } 
                   3229:        else{
                   3230:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3231:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3232:        } 
                   3233:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3234:        /*if(lli ==000.0)*/
                   3235:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3236:        ipmx +=1;
                   3237:        sw += weight[i];
                   3238:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3239:        /* if (lli < log(mytinydouble)){ */
                   3240:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3241:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3242:        /* } */
                   3243:       } /* end of wave */
                   3244:     } /* end of individual */
                   3245:   }  else if(mle==2){
                   3246:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3247:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3248:       for(mi=1; mi<= wav[i]-1; mi++){
                   3249:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3250:          for (j=1;j<=nlstate+ndeath;j++){
                   3251:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3252:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3253:          }
                   3254:        for(d=0; d<=dh[mi][i]; d++){
                   3255:          newm=savm;
                   3256:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3257:          cov[2]=agexact;
                   3258:          if(nagesqr==1)
                   3259:            cov[3]= agexact*agexact;
                   3260:          for (kk=1; kk<=cptcovage;kk++) {
                   3261:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3262:          }
                   3263:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3264:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3265:          savm=oldm;
                   3266:          oldm=newm;
                   3267:        } /* end mult */
                   3268:       
                   3269:        s1=s[mw[mi][i]][i];
                   3270:        s2=s[mw[mi+1][i]][i];
                   3271:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3272:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3273:        ipmx +=1;
                   3274:        sw += weight[i];
                   3275:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3276:       } /* end of wave */
                   3277:     } /* end of individual */
                   3278:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3279:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3280:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3281:       for(mi=1; mi<= wav[i]-1; mi++){
                   3282:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3283:          for (j=1;j<=nlstate+ndeath;j++){
                   3284:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3285:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3286:          }
                   3287:        for(d=0; d<dh[mi][i]; d++){
                   3288:          newm=savm;
                   3289:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3290:          cov[2]=agexact;
                   3291:          if(nagesqr==1)
                   3292:            cov[3]= agexact*agexact;
                   3293:          for (kk=1; kk<=cptcovage;kk++) {
                   3294:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3295:          }
                   3296:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3297:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3298:          savm=oldm;
                   3299:          oldm=newm;
                   3300:        } /* end mult */
                   3301:       
                   3302:        s1=s[mw[mi][i]][i];
                   3303:        s2=s[mw[mi+1][i]][i];
                   3304:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3305:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3306:        ipmx +=1;
                   3307:        sw += weight[i];
                   3308:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3309:       } /* end of wave */
                   3310:     } /* end of individual */
                   3311:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3312:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3313:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3314:       for(mi=1; mi<= wav[i]-1; mi++){
                   3315:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3316:          for (j=1;j<=nlstate+ndeath;j++){
                   3317:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3318:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3319:          }
                   3320:        for(d=0; d<dh[mi][i]; d++){
                   3321:          newm=savm;
                   3322:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3323:          cov[2]=agexact;
                   3324:          if(nagesqr==1)
                   3325:            cov[3]= agexact*agexact;
                   3326:          for (kk=1; kk<=cptcovage;kk++) {
                   3327:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3328:          }
1.126     brouard  3329:        
1.226     brouard  3330:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3331:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3332:          savm=oldm;
                   3333:          oldm=newm;
                   3334:        } /* end mult */
                   3335:       
                   3336:        s1=s[mw[mi][i]][i];
                   3337:        s2=s[mw[mi+1][i]][i];
                   3338:        if( s2 > nlstate){ 
                   3339:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3340:        } else if  ( s2==-1 ) { /* alive */
                   3341:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3342:            survp += out[s1][j];
                   3343:          lli= log(survp);
                   3344:        }else{
                   3345:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3346:        }
                   3347:        ipmx +=1;
                   3348:        sw += weight[i];
                   3349:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3350: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3351:       } /* end of wave */
                   3352:     } /* end of individual */
                   3353:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3354:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3355:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3356:       for(mi=1; mi<= wav[i]-1; mi++){
                   3357:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3358:          for (j=1;j<=nlstate+ndeath;j++){
                   3359:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3360:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3361:          }
                   3362:        for(d=0; d<dh[mi][i]; d++){
                   3363:          newm=savm;
                   3364:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3365:          cov[2]=agexact;
                   3366:          if(nagesqr==1)
                   3367:            cov[3]= agexact*agexact;
                   3368:          for (kk=1; kk<=cptcovage;kk++) {
                   3369:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3370:          }
1.126     brouard  3371:        
1.226     brouard  3372:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3373:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3374:          savm=oldm;
                   3375:          oldm=newm;
                   3376:        } /* end mult */
                   3377:       
                   3378:        s1=s[mw[mi][i]][i];
                   3379:        s2=s[mw[mi+1][i]][i];
                   3380:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3381:        ipmx +=1;
                   3382:        sw += weight[i];
                   3383:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3384:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3385:       } /* end of wave */
                   3386:     } /* end of individual */
                   3387:   } /* End of if */
                   3388:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3389:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3390:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3391:   return -l;
1.126     brouard  3392: }
                   3393: 
                   3394: /*************** log-likelihood *************/
                   3395: double funcone( double *x)
                   3396: {
1.228     brouard  3397:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3398:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3399:   int ioffset=0;
1.131     brouard  3400:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3401:   double **out;
                   3402:   double lli; /* Individual log likelihood */
                   3403:   double llt;
                   3404:   int s1, s2;
1.228     brouard  3405:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3406: 
1.126     brouard  3407:   double bbh, survp;
1.187     brouard  3408:   double agexact;
1.214     brouard  3409:   double agebegin, ageend;
1.126     brouard  3410:   /*extern weight */
                   3411:   /* We are differentiating ll according to initial status */
                   3412:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3413:   /*for(i=1;i<imx;i++) 
                   3414:     printf(" %d\n",s[4][i]);
                   3415:   */
                   3416:   cov[1]=1.;
                   3417: 
                   3418:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3419:   ioffset=0;
                   3420:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.225     brouard  3421:     ioffset=2+nagesqr+cptcovage;
1.232     brouard  3422:     /* Fixed */
1.224     brouard  3423:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3424:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3425:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3426:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3427: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3428: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3429: /*    cov[2+6]=covar[2][i]; V2  */
                   3430: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3431: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3432: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3433: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3434: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3435: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3436:     }
1.232     brouard  3437:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3438:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3439:     /* } */
1.231     brouard  3440:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3441:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3442:     /* } */
1.225     brouard  3443:     
1.233     brouard  3444: 
                   3445:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3446:     /* Wave varying (but not age varying) */
                   3447:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.233     brouard  3448:                                cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i];
1.232     brouard  3449:                        }
                   3450:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.231     brouard  3451:                                /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3452:                                /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
1.232     brouard  3453:                                /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3454:                                /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
1.231     brouard  3455:                                /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3456:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
                   3457:                        /*      iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3458:                        /*      /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3459:                        /*      cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
                   3460:       /* } */
1.126     brouard  3461:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.231     brouard  3462:                                for (j=1;j<=nlstate+ndeath;j++){
                   3463:                                        oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3464:                                        savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3465:                                }
1.214     brouard  3466:       
                   3467:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3468:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3469:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.231     brouard  3470:                                /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3471:                                        and mw[mi+1][i]. dh depends on stepm.*/
                   3472:                                newm=savm;
                   3473:                                agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3474:                                cov[2]=agexact;
                   3475:                                if(nagesqr==1)
                   3476:                                        cov[3]= agexact*agexact;
                   3477:                                for (kk=1; kk<=cptcovage;kk++) {
                   3478:                                        cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3479:                                }
                   3480:                                /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3481:                                /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3482:                                out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3483:                                                                                 1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3484:                                /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3485:                                /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3486:                                savm=oldm;
                   3487:                                oldm=newm;
1.126     brouard  3488:       } /* end mult */
                   3489:       
                   3490:       s1=s[mw[mi][i]][i];
                   3491:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3492:       /* if(s2==-1){ */
                   3493:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3494:       /*       /\* exit(1); *\/ */
                   3495:       /* } */
1.126     brouard  3496:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3497:       /* bias is positive if real duration
                   3498:        * is higher than the multiple of stepm and negative otherwise.
                   3499:        */
                   3500:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.232     brouard  3501:                                lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3502:       } else if  ( s2==-1 ) { /* alive */
1.232     brouard  3503:                                for (j=1,survp=0. ; j<=nlstate; j++) 
                   3504:                                        survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3505:                                lli= log(survp);
1.126     brouard  3506:       }else if (mle==1){
1.232     brouard  3507:                                lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3508:       } else if(mle==2){
1.232     brouard  3509:                                lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3510:       } else if(mle==3){  /* exponential inter-extrapolation */
1.232     brouard  3511:                                lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3512:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.232     brouard  3513:                                lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3514:       } else{  /* mle=0 back to 1 */
1.232     brouard  3515:                                lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3516:                                /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3517:       } /* End of if */
                   3518:       ipmx +=1;
                   3519:       sw += weight[i];
                   3520:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3521:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3522:       if(globpr){
1.232     brouard  3523:                                fprintf(ficresilk,"%9ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3524:  %11.6f %11.6f %11.6f ", \
1.232     brouard  3525:                                                                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3526:                                                                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3527:                                for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3528:                                        llt +=ll[k]*gipmx/gsw;
                   3529:                                        fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3530:                                }
                   3531:                                fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3532:       }
1.232     brouard  3533:        } /* end of wave */
                   3534: } /* end of individual */
                   3535: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3536: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3537: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3538: if(globpr==0){ /* First time we count the contributions and weights */
                   3539:        gipmx=ipmx;
                   3540:        gsw=sw;
                   3541: }
                   3542: return -l;
1.126     brouard  3543: }
                   3544: 
                   3545: 
                   3546: /*************** function likelione ***********/
                   3547: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3548: {
                   3549:   /* This routine should help understanding what is done with 
                   3550:      the selection of individuals/waves and
                   3551:      to check the exact contribution to the likelihood.
                   3552:      Plotting could be done.
                   3553:    */
                   3554:   int k;
                   3555: 
                   3556:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3557:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3558:     strcat(fileresilk,fileresu);
1.126     brouard  3559:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3560:       printf("Problem with resultfile: %s\n", fileresilk);
                   3561:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3562:     }
1.214     brouard  3563:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3564:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3565:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3566:     for(k=1; k<=nlstate; k++) 
                   3567:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3568:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3569:   }
                   3570: 
                   3571:   *fretone=(*funcone)(p);
                   3572:   if(*globpri !=0){
                   3573:     fclose(ficresilk);
1.205     brouard  3574:     if (mle ==0)
                   3575:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3576:     else if(mle >=1)
                   3577:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3578:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3579:     
1.208     brouard  3580:       
                   3581:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3582:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3583: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3584:     }
1.207     brouard  3585:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3586: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3587:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3588: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3589:     fflush(fichtm);
1.205     brouard  3590:   }
1.126     brouard  3591:   return;
                   3592: }
                   3593: 
                   3594: 
                   3595: /*********** Maximum Likelihood Estimation ***************/
                   3596: 
                   3597: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3598: {
1.165     brouard  3599:   int i,j, iter=0;
1.126     brouard  3600:   double **xi;
                   3601:   double fret;
                   3602:   double fretone; /* Only one call to likelihood */
                   3603:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3604: 
                   3605: #ifdef NLOPT
                   3606:   int creturn;
                   3607:   nlopt_opt opt;
                   3608:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3609:   double *lb;
                   3610:   double minf; /* the minimum objective value, upon return */
                   3611:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3612:   myfunc_data dinst, *d = &dinst;
                   3613: #endif
                   3614: 
                   3615: 
1.126     brouard  3616:   xi=matrix(1,npar,1,npar);
                   3617:   for (i=1;i<=npar;i++)
                   3618:     for (j=1;j<=npar;j++)
                   3619:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3620:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3621:   strcpy(filerespow,"POW_"); 
1.126     brouard  3622:   strcat(filerespow,fileres);
                   3623:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3624:     printf("Problem with resultfile: %s\n", filerespow);
                   3625:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3626:   }
                   3627:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3628:   for (i=1;i<=nlstate;i++)
                   3629:     for(j=1;j<=nlstate+ndeath;j++)
                   3630:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3631:   fprintf(ficrespow,"\n");
1.162     brouard  3632: #ifdef POWELL
1.126     brouard  3633:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3634: #endif
1.126     brouard  3635: 
1.162     brouard  3636: #ifdef NLOPT
                   3637: #ifdef NEWUOA
                   3638:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3639: #else
                   3640:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3641: #endif
                   3642:   lb=vector(0,npar-1);
                   3643:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3644:   nlopt_set_lower_bounds(opt, lb);
                   3645:   nlopt_set_initial_step1(opt, 0.1);
                   3646:   
                   3647:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3648:   d->function = func;
                   3649:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3650:   nlopt_set_min_objective(opt, myfunc, d);
                   3651:   nlopt_set_xtol_rel(opt, ftol);
                   3652:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3653:     printf("nlopt failed! %d\n",creturn); 
                   3654:   }
                   3655:   else {
                   3656:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3657:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3658:     iter=1; /* not equal */
                   3659:   }
                   3660:   nlopt_destroy(opt);
                   3661: #endif
1.126     brouard  3662:   free_matrix(xi,1,npar,1,npar);
                   3663:   fclose(ficrespow);
1.203     brouard  3664:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3665:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3666:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3667: 
                   3668: }
                   3669: 
                   3670: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3671: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3672: {
                   3673:   double  **a,**y,*x,pd;
1.203     brouard  3674:   /* double **hess; */
1.164     brouard  3675:   int i, j;
1.126     brouard  3676:   int *indx;
                   3677: 
                   3678:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3679:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3680:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3681:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3682:   double gompertz(double p[]);
1.203     brouard  3683:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3684: 
                   3685:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3686:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3687:   for (i=1;i<=npar;i++){
1.203     brouard  3688:     printf("%d-",i);fflush(stdout);
                   3689:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3690:    
                   3691:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3692:     
                   3693:     /*  printf(" %f ",p[i]);
                   3694:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3695:   }
                   3696:   
                   3697:   for (i=1;i<=npar;i++) {
                   3698:     for (j=1;j<=npar;j++)  {
                   3699:       if (j>i) { 
1.203     brouard  3700:        printf(".%d-%d",i,j);fflush(stdout);
                   3701:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3702:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3703:        
                   3704:        hess[j][i]=hess[i][j];    
                   3705:        /*printf(" %lf ",hess[i][j]);*/
                   3706:       }
                   3707:     }
                   3708:   }
                   3709:   printf("\n");
                   3710:   fprintf(ficlog,"\n");
                   3711: 
                   3712:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3713:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3714:   
                   3715:   a=matrix(1,npar,1,npar);
                   3716:   y=matrix(1,npar,1,npar);
                   3717:   x=vector(1,npar);
                   3718:   indx=ivector(1,npar);
                   3719:   for (i=1;i<=npar;i++)
                   3720:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3721:   ludcmp(a,npar,indx,&pd);
                   3722: 
                   3723:   for (j=1;j<=npar;j++) {
                   3724:     for (i=1;i<=npar;i++) x[i]=0;
                   3725:     x[j]=1;
                   3726:     lubksb(a,npar,indx,x);
                   3727:     for (i=1;i<=npar;i++){ 
                   3728:       matcov[i][j]=x[i];
                   3729:     }
                   3730:   }
                   3731: 
                   3732:   printf("\n#Hessian matrix#\n");
                   3733:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3734:   for (i=1;i<=npar;i++) { 
                   3735:     for (j=1;j<=npar;j++) { 
1.203     brouard  3736:       printf("%.6e ",hess[i][j]);
                   3737:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3738:     }
                   3739:     printf("\n");
                   3740:     fprintf(ficlog,"\n");
                   3741:   }
                   3742: 
1.203     brouard  3743:   /* printf("\n#Covariance matrix#\n"); */
                   3744:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3745:   /* for (i=1;i<=npar;i++) {  */
                   3746:   /*   for (j=1;j<=npar;j++) {  */
                   3747:   /*     printf("%.6e ",matcov[i][j]); */
                   3748:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3749:   /*   } */
                   3750:   /*   printf("\n"); */
                   3751:   /*   fprintf(ficlog,"\n"); */
                   3752:   /* } */
                   3753: 
1.126     brouard  3754:   /* Recompute Inverse */
1.203     brouard  3755:   /* for (i=1;i<=npar;i++) */
                   3756:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3757:   /* ludcmp(a,npar,indx,&pd); */
                   3758: 
                   3759:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3760: 
                   3761:   /* for (j=1;j<=npar;j++) { */
                   3762:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3763:   /*   x[j]=1; */
                   3764:   /*   lubksb(a,npar,indx,x); */
                   3765:   /*   for (i=1;i<=npar;i++){  */
                   3766:   /*     y[i][j]=x[i]; */
                   3767:   /*     printf("%.3e ",y[i][j]); */
                   3768:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3769:   /*   } */
                   3770:   /*   printf("\n"); */
                   3771:   /*   fprintf(ficlog,"\n"); */
                   3772:   /* } */
                   3773: 
                   3774:   /* Verifying the inverse matrix */
                   3775: #ifdef DEBUGHESS
                   3776:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3777: 
1.203     brouard  3778:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3779:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3780: 
                   3781:   for (j=1;j<=npar;j++) {
                   3782:     for (i=1;i<=npar;i++){ 
1.203     brouard  3783:       printf("%.2f ",y[i][j]);
                   3784:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3785:     }
                   3786:     printf("\n");
                   3787:     fprintf(ficlog,"\n");
                   3788:   }
1.203     brouard  3789: #endif
1.126     brouard  3790: 
                   3791:   free_matrix(a,1,npar,1,npar);
                   3792:   free_matrix(y,1,npar,1,npar);
                   3793:   free_vector(x,1,npar);
                   3794:   free_ivector(indx,1,npar);
1.203     brouard  3795:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3796: 
                   3797: 
                   3798: }
                   3799: 
                   3800: /*************** hessian matrix ****************/
                   3801: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3802: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3803:   int i;
                   3804:   int l=1, lmax=20;
1.203     brouard  3805:   double k1,k2, res, fx;
1.132     brouard  3806:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3807:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3808:   int k=0,kmax=10;
                   3809:   double l1;
                   3810: 
                   3811:   fx=func(x);
                   3812:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3813:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3814:     l1=pow(10,l);
                   3815:     delts=delt;
                   3816:     for(k=1 ; k <kmax; k=k+1){
                   3817:       delt = delta*(l1*k);
                   3818:       p2[theta]=x[theta] +delt;
1.145     brouard  3819:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3820:       p2[theta]=x[theta]-delt;
                   3821:       k2=func(p2)-fx;
                   3822:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3823:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3824:       
1.203     brouard  3825: #ifdef DEBUGHESSII
1.126     brouard  3826:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3827:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3828: #endif
                   3829:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3830:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3831:        k=kmax;
                   3832:       }
                   3833:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3834:        k=kmax; l=lmax*10;
1.126     brouard  3835:       }
                   3836:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3837:        delts=delt;
                   3838:       }
1.203     brouard  3839:     } /* End loop k */
1.126     brouard  3840:   }
                   3841:   delti[theta]=delts;
                   3842:   return res; 
                   3843:   
                   3844: }
                   3845: 
1.203     brouard  3846: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  3847: {
                   3848:   int i;
1.164     brouard  3849:   int l=1, lmax=20;
1.126     brouard  3850:   double k1,k2,k3,k4,res,fx;
1.132     brouard  3851:   double p2[MAXPARM+1];
1.203     brouard  3852:   int k, kmax=1;
                   3853:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  3854: 
                   3855:   int firstime=0;
1.203     brouard  3856:   
1.126     brouard  3857:   fx=func(x);
1.203     brouard  3858:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  3859:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  3860:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3861:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3862:     k1=func(p2)-fx;
                   3863:   
1.203     brouard  3864:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3865:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3866:     k2=func(p2)-fx;
                   3867:   
1.203     brouard  3868:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3869:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3870:     k3=func(p2)-fx;
                   3871:   
1.203     brouard  3872:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3873:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3874:     k4=func(p2)-fx;
1.203     brouard  3875:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   3876:     if(k1*k2*k3*k4 <0.){
1.208     brouard  3877:       firstime=1;
1.203     brouard  3878:       kmax=kmax+10;
1.208     brouard  3879:     }
                   3880:     if(kmax >=10 || firstime ==1){
1.218     brouard  3881:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
                   3882:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  3883:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3884:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3885:     }
                   3886: #ifdef DEBUGHESSIJ
                   3887:     v1=hess[thetai][thetai];
                   3888:     v2=hess[thetaj][thetaj];
                   3889:     cv12=res;
                   3890:     /* Computing eigen value of Hessian matrix */
                   3891:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   3892:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   3893:     if ((lc2 <0) || (lc1 <0) ){
                   3894:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   3895:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   3896:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3897:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3898:     }
1.126     brouard  3899: #endif
                   3900:   }
                   3901:   return res;
                   3902: }
                   3903: 
1.203     brouard  3904:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   3905: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   3906: /* { */
                   3907: /*   int i; */
                   3908: /*   int l=1, lmax=20; */
                   3909: /*   double k1,k2,k3,k4,res,fx; */
                   3910: /*   double p2[MAXPARM+1]; */
                   3911: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   3912: /*   int k=0,kmax=10; */
                   3913: /*   double l1; */
                   3914:   
                   3915: /*   fx=func(x); */
                   3916: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   3917: /*     l1=pow(10,l); */
                   3918: /*     delts=delt; */
                   3919: /*     for(k=1 ; k <kmax; k=k+1){ */
                   3920: /*       delt = delti*(l1*k); */
                   3921: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   3922: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   3923: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   3924: /*       k1=func(p2)-fx; */
                   3925:       
                   3926: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   3927: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   3928: /*       k2=func(p2)-fx; */
                   3929:       
                   3930: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   3931: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   3932: /*       k3=func(p2)-fx; */
                   3933:       
                   3934: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   3935: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   3936: /*       k4=func(p2)-fx; */
                   3937: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   3938: /* #ifdef DEBUGHESSIJ */
                   3939: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   3940: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   3941: /* #endif */
                   3942: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   3943: /*     k=kmax; */
                   3944: /*       } */
                   3945: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   3946: /*     k=kmax; l=lmax*10; */
                   3947: /*       } */
                   3948: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   3949: /*     delts=delt; */
                   3950: /*       } */
                   3951: /*     } /\* End loop k *\/ */
                   3952: /*   } */
                   3953: /*   delti[theta]=delts; */
                   3954: /*   return res;  */
                   3955: /* } */
                   3956: 
                   3957: 
1.126     brouard  3958: /************** Inverse of matrix **************/
                   3959: void ludcmp(double **a, int n, int *indx, double *d) 
                   3960: { 
                   3961:   int i,imax,j,k; 
                   3962:   double big,dum,sum,temp; 
                   3963:   double *vv; 
                   3964:  
                   3965:   vv=vector(1,n); 
                   3966:   *d=1.0; 
                   3967:   for (i=1;i<=n;i++) { 
                   3968:     big=0.0; 
                   3969:     for (j=1;j<=n;j++) 
                   3970:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   3971:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   3972:     vv[i]=1.0/big; 
                   3973:   } 
                   3974:   for (j=1;j<=n;j++) { 
                   3975:     for (i=1;i<j;i++) { 
                   3976:       sum=a[i][j]; 
                   3977:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   3978:       a[i][j]=sum; 
                   3979:     } 
                   3980:     big=0.0; 
                   3981:     for (i=j;i<=n;i++) { 
                   3982:       sum=a[i][j]; 
                   3983:       for (k=1;k<j;k++) 
                   3984:        sum -= a[i][k]*a[k][j]; 
                   3985:       a[i][j]=sum; 
                   3986:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   3987:        big=dum; 
                   3988:        imax=i; 
                   3989:       } 
                   3990:     } 
                   3991:     if (j != imax) { 
                   3992:       for (k=1;k<=n;k++) { 
                   3993:        dum=a[imax][k]; 
                   3994:        a[imax][k]=a[j][k]; 
                   3995:        a[j][k]=dum; 
                   3996:       } 
                   3997:       *d = -(*d); 
                   3998:       vv[imax]=vv[j]; 
                   3999:     } 
                   4000:     indx[j]=imax; 
                   4001:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4002:     if (j != n) { 
                   4003:       dum=1.0/(a[j][j]); 
                   4004:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4005:     } 
                   4006:   } 
                   4007:   free_vector(vv,1,n);  /* Doesn't work */
                   4008: ;
                   4009: } 
                   4010: 
                   4011: void lubksb(double **a, int n, int *indx, double b[]) 
                   4012: { 
                   4013:   int i,ii=0,ip,j; 
                   4014:   double sum; 
                   4015:  
                   4016:   for (i=1;i<=n;i++) { 
                   4017:     ip=indx[i]; 
                   4018:     sum=b[ip]; 
                   4019:     b[ip]=b[i]; 
                   4020:     if (ii) 
                   4021:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4022:     else if (sum) ii=i; 
                   4023:     b[i]=sum; 
                   4024:   } 
                   4025:   for (i=n;i>=1;i--) { 
                   4026:     sum=b[i]; 
                   4027:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4028:     b[i]=sum/a[i][i]; 
                   4029:   } 
                   4030: } 
                   4031: 
                   4032: void pstamp(FILE *fichier)
                   4033: {
1.196     brouard  4034:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4035: }
                   4036: 
                   4037: /************ Frequencies ********************/
1.226     brouard  4038: void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
                   4039:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4040:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
                   4041: {  /* Some frequencies */
                   4042:   
1.227     brouard  4043:   int i, m, jk, j1, bool, z1,j, k, iv;
1.226     brouard  4044:   int iind=0, iage=0;
                   4045:   int mi; /* Effective wave */
                   4046:   int first;
                   4047:   double ***freq; /* Frequencies */
                   4048:   double *meanq;
                   4049:   double **meanqt;
                   4050:   double *pp, **prop, *posprop, *pospropt;
                   4051:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4052:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4053:   double agebegin, ageend;
                   4054:     
                   4055:   pp=vector(1,nlstate);
                   4056:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4057:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4058:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4059:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4060:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4061:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4062:   strcpy(fileresp,"P_");
                   4063:   strcat(fileresp,fileresu);
                   4064:   /*strcat(fileresphtm,fileresu);*/
                   4065:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4066:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4067:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4068:     exit(0);
                   4069:   }
1.214     brouard  4070: 
1.226     brouard  4071:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4072:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4073:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4074:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4075:     fflush(ficlog);
                   4076:     exit(70); 
                   4077:   }
                   4078:   else{
                   4079:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.214     brouard  4080: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   4081: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4082:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4083:   }
                   4084:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition</h4>\n",fileresphtm, fileresphtm);
1.214     brouard  4085:     
1.226     brouard  4086:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4087:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4088:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4089:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4090:     fflush(ficlog);
                   4091:     exit(70); 
                   4092:   }
                   4093:   else{
                   4094:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.214     brouard  4095: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   4096: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4097:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4098:   }
                   4099:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions by age at begin of transition </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
1.214     brouard  4100: 
1.226     brouard  4101:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4102:   j1=0;
1.126     brouard  4103:   
1.227     brouard  4104:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4105:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4106:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.220     brouard  4107: 
1.226     brouard  4108:   first=1;
1.220     brouard  4109: 
1.226     brouard  4110:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4111:      reference=low_education V1=0,V2=0
                   4112:      med_educ                V1=1 V2=0, 
                   4113:      high_educ               V1=0 V2=1
                   4114:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4115:   */
1.126     brouard  4116: 
1.227     brouard  4117:   for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives V4=0, V3=0 for example, fixed or varying covariates */
1.226     brouard  4118:     posproptt=0.;
                   4119:     /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4120:       scanf("%d", i);*/
                   4121:     for (i=-5; i<=nlstate+ndeath; i++)  
                   4122:       for (jk=-5; jk<=nlstate+ndeath; jk++)  
1.231     brouard  4123:                                for(m=iagemin; m <= iagemax+3; m++)
                   4124:                                        freq[i][jk][m]=0;
                   4125:                
1.226     brouard  4126:     for (i=1; i<=nlstate; i++)  {
                   4127:       for(m=iagemin; m <= iagemax+3; m++)
1.231     brouard  4128:                                prop[i][m]=0;
1.226     brouard  4129:       posprop[i]=0;
                   4130:       pospropt[i]=0;
                   4131:     }
1.227     brouard  4132:     /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4133:     /*   meanq[z1]+=0.; */
                   4134:     /*   for(m=1;m<=lastpass;m++){ */
                   4135:     /*         meanqt[m][z1]=0.; */
                   4136:     /*   } */
                   4137:     /* } */
1.231     brouard  4138:                
1.226     brouard  4139:     dateintsum=0;
                   4140:     k2cpt=0;
1.227     brouard  4141:     /* For that combination of covariate j1, we count and print the frequencies in one pass */
1.226     brouard  4142:     for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4143:       bool=1;
1.227     brouard  4144:       if(anyvaryingduminmodel==0){ /* If All fixed covariates */
1.234     brouard  4145:        if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
1.227     brouard  4146:          /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4147:          /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4148:          /* } */
1.234     brouard  4149:          for (z1=1; z1<=cptcoveff; z1++) {  
                   4150:            /* if(Tvaraff[z1] ==-20){ */
                   4151:            /*   /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4152:            /* }else  if(Tvaraff[z1] ==-10){ */
                   4153:            /*   /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4154:            /* }else  */
                   4155:            if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){
                   4156:              /* Tests if this individual iind responded to j1 (V4=1 V3=0) */
                   4157:              bool=0;
                   4158:              /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4159:                 bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4160:                 j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4161:              /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4162:            } /* Onlyf fixed */
                   4163:          } /* end z1 */
                   4164:        } /* cptcovn > 0 */
1.227     brouard  4165:       } /* end any */
                   4166:       if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
1.234     brouard  4167:        /* for(m=firstpass; m<=lastpass; m++){ */
                   4168:        for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4169:          m=mw[mi][iind];
                   4170:          if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4171:            for (z1=1; z1<=cptcoveff; z1++) {
                   4172:              if( Fixed[Tmodelind[z1]]==1){
                   4173:                iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4174:                if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4175:                  bool=0;
                   4176:              }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4177:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4178:                  bool=0;
                   4179:                }
                   4180:              }
                   4181:            }
                   4182:          }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4183:          /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4184:          if(bool==1){
                   4185:            /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4186:               and mw[mi+1][iind]. dh depends on stepm. */
                   4187:            agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4188:            ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4189:            if(m >=firstpass && m <=lastpass){
                   4190:              k2=anint[m][iind]+(mint[m][iind]/12.);
                   4191:              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4192:              if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4193:              if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4194:              if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4195:                prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4196:              if (m<lastpass) {
                   4197:                /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4198:                /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4199:                if(s[m][iind]==-1)
                   4200:                  printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4201:                freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4202:                /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4203:                freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
                   4204:              }
                   4205:            } /* end if between passes */  
                   4206:            if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99)) {
                   4207:              dateintsum=dateintsum+k2;
                   4208:              k2cpt++;
                   4209:              /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
                   4210:            }
                   4211:          } /* end bool 2 */
                   4212:        } /* end m */
1.226     brouard  4213:       } /* end bool */
                   4214:     } /* end iind = 1 to imx */
                   4215:     /* prop[s][age] is feeded for any initial and valid live state as well as
                   4216:        freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
1.231     brouard  4217:                
                   4218:                
1.226     brouard  4219:     /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4220:     pstamp(ficresp);
1.227     brouard  4221:     /* if  (ncoveff>0) { */
                   4222:     if  (cptcoveff>0) {
1.226     brouard  4223:       fprintf(ficresp, "\n#********** Variable "); 
                   4224:       fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4225:       fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
1.227     brouard  4226:       for (z1=1; z1<=cptcoveff; z1++){
1.234     brouard  4227:        fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4228:        fprintf(ficresphtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4229:        fprintf(ficresphtmfr, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.226     brouard  4230:       }
                   4231:       fprintf(ficresp, "**********\n#");
                   4232:       fprintf(ficresphtm, "**********</h3>\n");
                   4233:       fprintf(ficresphtmfr, "**********</h3>\n");
                   4234:       fprintf(ficlog, "\n#********** Variable "); 
1.227     brouard  4235:       for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.226     brouard  4236:       fprintf(ficlog, "**********\n");
                   4237:     }
                   4238:     fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4239:     for(i=1; i<=nlstate;i++) {
                   4240:       fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
                   4241:       fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4242:     }
                   4243:     fprintf(ficresp, "\n");
                   4244:     fprintf(ficresphtm, "\n");
1.231     brouard  4245:                
1.226     brouard  4246:     /* Header of frequency table by age */
                   4247:     fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4248:     fprintf(ficresphtmfr,"<th>Age</th> ");
                   4249:     for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4250:       for(m=-1; m <=nlstate+ndeath; m++){
1.234     brouard  4251:        if(jk!=0 && m!=0)
                   4252:          fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.226     brouard  4253:       }
                   4254:     }
                   4255:     fprintf(ficresphtmfr, "\n");
1.231     brouard  4256:                
1.226     brouard  4257:     /* For each age */
                   4258:     for(iage=iagemin; iage <= iagemax+3; iage++){
                   4259:       fprintf(ficresphtm,"<tr>");
                   4260:       if(iage==iagemax+1){
1.231     brouard  4261:                                fprintf(ficlog,"1");
                   4262:                                fprintf(ficresphtmfr,"<tr><th>0</th> ");
1.226     brouard  4263:       }else if(iage==iagemax+2){
1.231     brouard  4264:                                fprintf(ficlog,"0");
                   4265:                                fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
1.226     brouard  4266:       }else if(iage==iagemax+3){
1.231     brouard  4267:                                fprintf(ficlog,"Total");
                   4268:                                fprintf(ficresphtmfr,"<tr><th>Total</th> ");
1.226     brouard  4269:       }else{
1.231     brouard  4270:                                if(first==1){
                   4271:                                        first=0;
                   4272:                                        printf("See log file for details...\n");
                   4273:                                }
                   4274:                                fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4275:                                fprintf(ficlog,"Age %d", iage);
1.226     brouard  4276:       }
                   4277:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4278:                                for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4279:                                        pp[jk] += freq[jk][m][iage]; 
1.226     brouard  4280:       }
                   4281:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4282:                                for(m=-1, pos=0; m <=0 ; m++)
                   4283:                                        pos += freq[jk][m][iage];
                   4284:                                if(pp[jk]>=1.e-10){
                   4285:                                        if(first==1){
                   4286:                                                printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4287:                                        }
                   4288:                                        fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4289:                                }else{
                   4290:                                        if(first==1)
                   4291:                                                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4292:                                        fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4293:                                }
1.226     brouard  4294:       }
1.231     brouard  4295:                        
1.226     brouard  4296:       for(jk=1; jk <=nlstate ; jk++){ 
1.231     brouard  4297:                                /* posprop[jk]=0; */
                   4298:                                for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4299:                                        pp[jk] += freq[jk][m][iage];
1.226     brouard  4300:       }        /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
1.231     brouard  4301:                        
1.226     brouard  4302:       for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
1.231     brouard  4303:                                pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4304:                                posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4305:                                                                                                                                                                        from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4306:                                pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4307:                                                                                                                                                                from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
1.226     brouard  4308:       }
                   4309:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4310:                                if(pos>=1.e-5){
                   4311:                                        if(first==1)
                   4312:                                                printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4313:                                        fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4314:                                }else{
                   4315:                                        if(first==1)
                   4316:                                                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4317:                                        fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4318:                                }
                   4319:                                if( iage <= iagemax){
                   4320:                                        if(pos>=1.e-5){
                   4321:                                                fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4322:                                                fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4323:                                                /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4324:                                                /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4325:                                        }
                   4326:                                        else{
                   4327:                                                fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4328:                                                fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4329:                                        }
                   4330:                                }
                   4331:                                pospropt[jk] +=posprop[jk];
1.226     brouard  4332:       } /* end loop jk */
                   4333:       /* pospropt=0.; */
                   4334:       for(jk=-1; jk <=nlstate+ndeath; jk++){
1.231     brouard  4335:                                for(m=-1; m <=nlstate+ndeath; m++){
                   4336:                                        if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4337:                                                if(first==1){
                   4338:                                                        printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4339:                                                }
                   4340:                                                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4341:                                        }
                   4342:                                        if(jk!=0 && m!=0)
                   4343:                                                fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
                   4344:                                }
1.226     brouard  4345:       } /* end loop jk */
                   4346:       posproptt=0.; 
                   4347:       for(jk=1; jk <=nlstate; jk++){
1.231     brouard  4348:                                posproptt += pospropt[jk];
1.226     brouard  4349:       }
                   4350:       fprintf(ficresphtmfr,"</tr>\n ");
                   4351:       if(iage <= iagemax){
1.231     brouard  4352:                                fprintf(ficresp,"\n");
                   4353:                                fprintf(ficresphtm,"</tr>\n");
1.226     brouard  4354:       }
                   4355:       if(first==1)
1.231     brouard  4356:                                printf("Others in log...\n");
1.226     brouard  4357:       fprintf(ficlog,"\n");
                   4358:     } /* end loop age iage */
                   4359:     fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4360:     for(jk=1; jk <=nlstate ; jk++){
                   4361:       if(posproptt < 1.e-5){
1.231     brouard  4362:                                fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt);   
1.226     brouard  4363:       }else{
1.231     brouard  4364:                                fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);    
1.226     brouard  4365:       }
                   4366:     }
                   4367:     fprintf(ficresphtm,"</tr>\n");
                   4368:     fprintf(ficresphtm,"</table>\n");
                   4369:     fprintf(ficresphtmfr,"</table>\n");
                   4370:     if(posproptt < 1.e-5){
                   4371:       fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4372:       fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4373:       fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4374:       invalidvarcomb[j1]=1;
                   4375:     }else{
                   4376:       fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4377:       invalidvarcomb[j1]=0;
                   4378:     }
                   4379:     fprintf(ficresphtmfr,"</table>\n");
                   4380:   } /* end selected combination of covariate j1 */
                   4381:   dateintmean=dateintsum/k2cpt; 
1.231     brouard  4382:        
1.226     brouard  4383:   fclose(ficresp);
                   4384:   fclose(ficresphtm);
                   4385:   fclose(ficresphtmfr);
                   4386:   free_vector(meanq,1,nqfveff);
                   4387:   free_matrix(meanqt,1,lastpass,1,nqtveff);
                   4388:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4389:   free_vector(pospropt,1,nlstate);
                   4390:   free_vector(posprop,1,nlstate);
                   4391:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4392:   free_vector(pp,1,nlstate);
                   4393:   /* End of freqsummary */
                   4394: }
1.126     brouard  4395: 
                   4396: /************ Prevalence ********************/
1.227     brouard  4397: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4398: {  
                   4399:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4400:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4401:      We still use firstpass and lastpass as another selection.
                   4402:   */
1.126     brouard  4403:  
1.227     brouard  4404:   int i, m, jk, j1, bool, z1,j, iv;
                   4405:   int mi; /* Effective wave */
                   4406:   int iage;
                   4407:   double agebegin, ageend;
                   4408: 
                   4409:   double **prop;
                   4410:   double posprop; 
                   4411:   double  y2; /* in fractional years */
                   4412:   int iagemin, iagemax;
                   4413:   int first; /** to stop verbosity which is redirected to log file */
                   4414: 
                   4415:   iagemin= (int) agemin;
                   4416:   iagemax= (int) agemax;
                   4417:   /*pp=vector(1,nlstate);*/
                   4418:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4419:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4420:   j1=0;
1.222     brouard  4421:   
1.227     brouard  4422:   /*j=cptcoveff;*/
                   4423:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4424:   
1.227     brouard  4425:   first=1;
                   4426:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4427:     for (i=1; i<=nlstate; i++)  
                   4428:       for(iage=iagemin-AGEMARGE; iage <= iagemax+3+AGEMARGE; iage++)
                   4429:        prop[i][iage]=0.0;
                   4430:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4431:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4432:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4433:     
                   4434:     for (i=1; i<=imx; i++) { /* Each individual */
                   4435:       bool=1;
                   4436:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4437:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4438:        m=mw[mi][i];
                   4439:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4440:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4441:        for (z1=1; z1<=cptcoveff; z1++){
                   4442:          if( Fixed[Tmodelind[z1]]==1){
                   4443:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4444:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4445:              bool=0;
                   4446:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4447:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4448:              bool=0;
                   4449:            }
                   4450:        }
                   4451:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4452:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4453:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4454:          if(m >=firstpass && m <=lastpass){
                   4455:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4456:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4457:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4458:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
                   4459:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+3+AGEMARGE){
                   4460:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4461:                exit(1);
                   4462:              }
                   4463:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4464:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4465:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4466:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4467:              } /* end valid statuses */ 
                   4468:            } /* end selection of dates */
                   4469:          } /* end selection of waves */
                   4470:        } /* end bool */
                   4471:       } /* end wave */
                   4472:     } /* end individual */
                   4473:     for(i=iagemin; i <= iagemax+3; i++){  
                   4474:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4475:        posprop += prop[jk][i]; 
                   4476:       } 
                   4477:       
                   4478:       for(jk=1; jk <=nlstate ; jk++){      
                   4479:        if( i <=  iagemax){ 
                   4480:          if(posprop>=1.e-5){ 
                   4481:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4482:          } else{
                   4483:            if(first==1){
                   4484:              first=0;
                   4485:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4486:            }
                   4487:          }
                   4488:        } 
                   4489:       }/* end jk */ 
                   4490:     }/* end i */ 
1.222     brouard  4491:      /*} *//* end i1 */
1.227     brouard  4492:   } /* end j1 */
1.222     brouard  4493:   
1.227     brouard  4494:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4495:   /*free_vector(pp,1,nlstate);*/
                   4496:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4497: }  /* End of prevalence */
1.126     brouard  4498: 
                   4499: /************* Waves Concatenation ***************/
                   4500: 
                   4501: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4502: {
                   4503:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4504:      Death is a valid wave (if date is known).
                   4505:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4506:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4507:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4508:   */
1.126     brouard  4509: 
1.224     brouard  4510:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4511:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4512:      double sum=0., jmean=0.;*/
1.224     brouard  4513:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4514:   int j, k=0,jk, ju, jl;
                   4515:   double sum=0.;
                   4516:   first=0;
1.214     brouard  4517:   firstwo=0;
1.217     brouard  4518:   firsthree=0;
1.218     brouard  4519:   firstfour=0;
1.164     brouard  4520:   jmin=100000;
1.126     brouard  4521:   jmax=-1;
                   4522:   jmean=0.;
1.224     brouard  4523: 
                   4524: /* Treating live states */
1.214     brouard  4525:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4526:     mi=0;  /* First valid wave */
1.227     brouard  4527:     mli=0; /* Last valid wave */
1.126     brouard  4528:     m=firstpass;
1.214     brouard  4529:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4530:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4531:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4532:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4533:        mw[++mi][i]=m;
                   4534:        mli=m;
1.224     brouard  4535:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4536:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4537:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4538:       }
1.227     brouard  4539:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4540: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4541:        break;
1.224     brouard  4542: #else
1.227     brouard  4543:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4544:          if(firsthree == 0){
                   4545:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4546:            firsthree=1;
                   4547:          }
                   4548:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4549:          mw[++mi][i]=m;
                   4550:          mli=m;
                   4551:        }
                   4552:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4553:          nbwarn++;
                   4554:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4555:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4556:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4557:          }
                   4558:          break;
                   4559:        }
                   4560:        break;
1.224     brouard  4561: #endif
1.227     brouard  4562:       }/* End m >= lastpass */
1.126     brouard  4563:     }/* end while */
1.224     brouard  4564: 
1.227     brouard  4565:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4566:     /* After last pass */
1.224     brouard  4567: /* Treating death states */
1.214     brouard  4568:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4569:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4570:       /* } */
1.126     brouard  4571:       mi++;    /* Death is another wave */
                   4572:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4573:       /* Only death is a correct wave */
1.126     brouard  4574:       mw[mi][i]=m;
1.224     brouard  4575:     }
                   4576: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4577:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4578:       /* m++; */
                   4579:       /* mi++; */
                   4580:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4581:       /* mw[mi][i]=m; */
1.218     brouard  4582:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4583:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4584:          nbwarn++;
                   4585:          if(firstfiv==0){
                   4586:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4587:            firstfiv=1;
                   4588:          }else{
                   4589:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4590:          }
                   4591:        }else{ /* Death occured afer last wave potential bias */
                   4592:          nberr++;
                   4593:          if(firstwo==0){
                   4594:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4595:            firstwo=1;
                   4596:          }
                   4597:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4598:        }
1.218     brouard  4599:       }else{ /* end date of interview is known */
1.227     brouard  4600:        /* death is known but not confirmed by death status at any wave */
                   4601:        if(firstfour==0){
                   4602:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4603:          firstfour=1;
                   4604:        }
                   4605:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4606:       }
1.224     brouard  4607:     } /* end if date of death is known */
                   4608: #endif
                   4609:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4610:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4611:     if(mi==0){
                   4612:       nbwarn++;
                   4613:       if(first==0){
1.227     brouard  4614:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4615:        first=1;
1.126     brouard  4616:       }
                   4617:       if(first==1){
1.227     brouard  4618:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4619:       }
                   4620:     } /* end mi==0 */
                   4621:   } /* End individuals */
1.214     brouard  4622:   /* wav and mw are no more changed */
1.223     brouard  4623:        
1.214     brouard  4624:   
1.126     brouard  4625:   for(i=1; i<=imx; i++){
                   4626:     for(mi=1; mi<wav[i];mi++){
                   4627:       if (stepm <=0)
1.227     brouard  4628:        dh[mi][i]=1;
1.126     brouard  4629:       else{
1.227     brouard  4630:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   4631:          if (agedc[i] < 2*AGESUP) {
                   4632:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   4633:            if(j==0) j=1;  /* Survives at least one month after exam */
                   4634:            else if(j<0){
                   4635:              nberr++;
                   4636:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4637:              j=1; /* Temporary Dangerous patch */
                   4638:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4639:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4640:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4641:            }
                   4642:            k=k+1;
                   4643:            if (j >= jmax){
                   4644:              jmax=j;
                   4645:              ijmax=i;
                   4646:            }
                   4647:            if (j <= jmin){
                   4648:              jmin=j;
                   4649:              ijmin=i;
                   4650:            }
                   4651:            sum=sum+j;
                   4652:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   4653:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   4654:          }
                   4655:        }
                   4656:        else{
                   4657:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  4658: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  4659:                                        
1.227     brouard  4660:          k=k+1;
                   4661:          if (j >= jmax) {
                   4662:            jmax=j;
                   4663:            ijmax=i;
                   4664:          }
                   4665:          else if (j <= jmin){
                   4666:            jmin=j;
                   4667:            ijmin=i;
                   4668:          }
                   4669:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   4670:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   4671:          if(j<0){
                   4672:            nberr++;
                   4673:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4674:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4675:          }
                   4676:          sum=sum+j;
                   4677:        }
                   4678:        jk= j/stepm;
                   4679:        jl= j -jk*stepm;
                   4680:        ju= j -(jk+1)*stepm;
                   4681:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   4682:          if(jl==0){
                   4683:            dh[mi][i]=jk;
                   4684:            bh[mi][i]=0;
                   4685:          }else{ /* We want a negative bias in order to only have interpolation ie
                   4686:                  * to avoid the price of an extra matrix product in likelihood */
                   4687:            dh[mi][i]=jk+1;
                   4688:            bh[mi][i]=ju;
                   4689:          }
                   4690:        }else{
                   4691:          if(jl <= -ju){
                   4692:            dh[mi][i]=jk;
                   4693:            bh[mi][i]=jl;       /* bias is positive if real duration
                   4694:                                 * is higher than the multiple of stepm and negative otherwise.
                   4695:                                 */
                   4696:          }
                   4697:          else{
                   4698:            dh[mi][i]=jk+1;
                   4699:            bh[mi][i]=ju;
                   4700:          }
                   4701:          if(dh[mi][i]==0){
                   4702:            dh[mi][i]=1; /* At least one step */
                   4703:            bh[mi][i]=ju; /* At least one step */
                   4704:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   4705:          }
                   4706:        } /* end if mle */
1.126     brouard  4707:       }
                   4708:     } /* end wave */
                   4709:   }
                   4710:   jmean=sum/k;
                   4711:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  4712:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  4713: }
1.126     brouard  4714: 
                   4715: /*********** Tricode ****************************/
1.220     brouard  4716:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.126     brouard  4717: {
1.144     brouard  4718:   /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   4719:   /*     Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
1.169     brouard  4720:    * Boring subroutine which should only output nbcode[Tvar[j]][k]
1.224     brouard  4721:    * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   4722:    * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
1.144     brouard  4723:   */
1.130     brouard  4724: 
1.145     brouard  4725:   int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
1.136     brouard  4726:   int modmaxcovj=0; /* Modality max of covariates j */
1.145     brouard  4727:   int cptcode=0; /* Modality max of covariates j */
                   4728:   int modmincovj=0; /* Modality min of covariates j */
                   4729: 
                   4730: 
1.220     brouard  4731:   /* cptcoveff=0;  */
1.224     brouard  4732:        /* *cptcov=0; */
1.126     brouard  4733:  
1.144     brouard  4734:   for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  4735: 
1.224     brouard  4736:   /* Loop on covariates without age and products and no quantitative variable */
                   4737:   /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
1.227     brouard  4738:   for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   4739:     for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   4740:     if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   4741:       switch(Fixed[k]) {
                   4742:       case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.231     brouard  4743:                                for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   4744:                                        ij=(int)(covar[Tvar[k]][i]);
                   4745:                                        /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   4746:                                         * If product of Vn*Vm, still boolean *:
                   4747:                                         * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   4748:                                         * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   4749:                                        /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   4750:                                                 modality of the nth covariate of individual i. */
                   4751:                                        if (ij > modmaxcovj)
                   4752:                                                modmaxcovj=ij; 
                   4753:                                        else if (ij < modmincovj) 
                   4754:                                                modmincovj=ij; 
                   4755:                                        if ((ij < -1) && (ij > NCOVMAX)){
                   4756:                                                printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   4757:                                                exit(1);
                   4758:                                        }else
                   4759:                                                Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   4760:                                        /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   4761:                                        /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   4762:                                        /* getting the maximum value of the modality of the covariate
                   4763:                                                 (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   4764:                                                 female ies 1, then modmaxcovj=1.
                   4765:                                        */
                   4766:                                } /* end for loop on individuals i */
                   4767:                                printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4768:                                fprintf(ficlog," Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4769:                                cptcode=modmaxcovj;
                   4770:                                /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   4771:                                /*for (i=0; i<=cptcode; i++) {*/
                   4772:                                for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   4773:                                        printf("Frequencies of covariates %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4774:                                        fprintf(ficlog, "Frequencies of covariates %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4775:                                        if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   4776:                                                if( j != -1){
                   4777:                                                        ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   4778:                                                                                                                                 covariate for which somebody answered excluding 
                   4779:                                                                                                                                 undefined. Usually 2: 0 and 1. */
                   4780:                                                }
                   4781:                                                ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   4782:                                                                                                                                                covariate for which somebody answered including 
                   4783:                                                                                                                                                undefined. Usually 3: -1, 0 and 1. */
                   4784:                                        }       /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   4785:                                                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   4786:                                } /* Ndum[-1] number of undefined modalities */
                   4787:                        
                   4788:                                /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   4789:                                /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   4790:                                /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   4791:                                /* modmincovj=3; modmaxcovj = 7; */
                   4792:                                /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   4793:                                /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   4794:                          /*             defining two dummy variables: variables V1_1 and V1_2.*/
                   4795:              /* nbcode[Tvar[j]][ij]=k; */
                   4796:              /* nbcode[Tvar[j]][1]=0; */
                   4797:              /* nbcode[Tvar[j]][2]=1; */
                   4798:              /* nbcode[Tvar[j]][3]=2; */
                   4799:              /* To be continued (not working yet). */
                   4800:              ij=0; /* ij is similar to i but can jump over null modalities */
                   4801:                                for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   4802:          if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   4803:                  break;
                   4804:                }
                   4805:                                        ij++;
                   4806:                                        nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   4807:                                        cptcode = ij; /* New max modality for covar j */
                   4808:                                } /* end of loop on modality i=-1 to 1 or more */
                   4809:                                break;
1.227     brouard  4810:       case 1: /* Testing on varying covariate, could be simple and
                   4811:               * should look at waves or product of fixed *
                   4812:               * varying. No time to test -1, assuming 0 and 1 only */
1.231     brouard  4813:                                ij=0;
                   4814:                                for(i=0; i<=1;i++){
                   4815:                                        nbcode[Tvar[k]][++ij]=i;
                   4816:                                }
                   4817:                                break;
1.227     brouard  4818:       default:
1.231     brouard  4819:                                break;
1.227     brouard  4820:       } /* end switch */
                   4821:     } /* end dummy test */
1.225     brouard  4822:     
1.192     brouard  4823:     /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   4824:     /*         /\*recode from 0 *\/ */
                   4825:     /*                                      k is a modality. If we have model=V1+V1*sex  */
                   4826:     /*                                      then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   4827:     /*                                   But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   4828:     /*         } */
                   4829:     /*         /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   4830:     /*         if (ij > ncodemax[j]) { */
                   4831:     /*           printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   4832:     /*           fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   4833:     /*           break; */
                   4834:     /*         } */
                   4835:     /*   }  /\* end of loop on modality k *\/ */
1.137     brouard  4836:   } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   4837:   
1.225     brouard  4838:   for (k=-1; k< maxncov; k++) Ndum[k]=0; 
1.227     brouard  4839:   /* Look at fixed dummy (single or product) covariates to check empty modalities */
1.187     brouard  4840:   for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
1.225     brouard  4841:     /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
1.227     brouard  4842:     ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   4843:     Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   4844:     /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
1.225     brouard  4845:   } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   4846:   
                   4847:   ij=0;
1.227     brouard  4848:   /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   4849:   for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
1.225     brouard  4850:     /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
1.227     brouard  4851:     /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   4852:     if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   4853:       /* If product not in single variable we don't print results */
1.225     brouard  4854:       /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
1.230     brouard  4855:       ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   4856:       Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   4857:       Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
1.231     brouard  4858:       TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
1.227     brouard  4859:       if(Fixed[k]!=0)
                   4860:         anyvaryingduminmodel=1;
1.231     brouard  4861:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   4862:                        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   4863:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   4864:                        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   4865:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   4866:                        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
1.227     brouard  4867:     } 
1.225     brouard  4868:   } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   4869:   /* ij--; */
                   4870:   /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   4871:   *cptcov=ij; /*Number of total real effective covariates: effective
1.231     brouard  4872:                                                         * because they can be excluded from the model and real
                   4873:                                                         * if in the model but excluded because missing values, but how to get k from ij?*/
1.227     brouard  4874:   for(j=ij+1; j<= cptcovt; j++){
                   4875:     Tvaraff[j]=0;
                   4876:     Tmodelind[j]=0;
                   4877:   }
1.228     brouard  4878:   for(j=ntveff+1; j<= cptcovt; j++){
                   4879:     TmodelInvind[j]=0;
                   4880:   }
1.227     brouard  4881:   /* To be sorted */
                   4882:   ;
1.126     brouard  4883: }
                   4884: 
1.145     brouard  4885: 
1.126     brouard  4886: /*********** Health Expectancies ****************/
                   4887: 
1.235   ! brouard  4888:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  4889: 
                   4890: {
                   4891:   /* Health expectancies, no variances */
1.164     brouard  4892:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  4893:   int nhstepma, nstepma; /* Decreasing with age */
                   4894:   double age, agelim, hf;
                   4895:   double ***p3mat;
                   4896:   double eip;
                   4897: 
                   4898:   pstamp(ficreseij);
                   4899:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   4900:   fprintf(ficreseij,"# Age");
                   4901:   for(i=1; i<=nlstate;i++){
                   4902:     for(j=1; j<=nlstate;j++){
                   4903:       fprintf(ficreseij," e%1d%1d ",i,j);
                   4904:     }
                   4905:     fprintf(ficreseij," e%1d. ",i);
                   4906:   }
                   4907:   fprintf(ficreseij,"\n");
                   4908: 
                   4909:   
                   4910:   if(estepm < stepm){
                   4911:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   4912:   }
                   4913:   else  hstepm=estepm;   
                   4914:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   4915:    * This is mainly to measure the difference between two models: for example
                   4916:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   4917:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   4918:    * progression in between and thus overestimating or underestimating according
                   4919:    * to the curvature of the survival function. If, for the same date, we 
                   4920:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   4921:    * to compare the new estimate of Life expectancy with the same linear 
                   4922:    * hypothesis. A more precise result, taking into account a more precise
                   4923:    * curvature will be obtained if estepm is as small as stepm. */
                   4924: 
                   4925:   /* For example we decided to compute the life expectancy with the smallest unit */
                   4926:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   4927:      nhstepm is the number of hstepm from age to agelim 
                   4928:      nstepm is the number of stepm from age to agelin. 
                   4929:      Look at hpijx to understand the reason of that which relies in memory size
                   4930:      and note for a fixed period like estepm months */
                   4931:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   4932:      survival function given by stepm (the optimization length). Unfortunately it
                   4933:      means that if the survival funtion is printed only each two years of age and if
                   4934:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   4935:      results. So we changed our mind and took the option of the best precision.
                   4936:   */
                   4937:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   4938: 
                   4939:   agelim=AGESUP;
                   4940:   /* If stepm=6 months */
                   4941:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   4942:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   4943:     
                   4944: /* nhstepm age range expressed in number of stepm */
                   4945:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   4946:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4947:   /* if (stepm >= YEARM) hstepm=1;*/
                   4948:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   4949:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4950: 
                   4951:   for (age=bage; age<=fage; age ++){ 
                   4952:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   4953:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4954:     /* if (stepm >= YEARM) hstepm=1;*/
                   4955:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   4956: 
                   4957:     /* If stepm=6 months */
                   4958:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   4959:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   4960:     
1.235   ! brouard  4961:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  4962:     
                   4963:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   4964:     
                   4965:     printf("%d|",(int)age);fflush(stdout);
                   4966:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   4967:     
                   4968:     /* Computing expectancies */
                   4969:     for(i=1; i<=nlstate;i++)
                   4970:       for(j=1; j<=nlstate;j++)
                   4971:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   4972:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   4973:          
                   4974:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   4975: 
                   4976:        }
                   4977: 
                   4978:     fprintf(ficreseij,"%3.0f",age );
                   4979:     for(i=1; i<=nlstate;i++){
                   4980:       eip=0;
                   4981:       for(j=1; j<=nlstate;j++){
                   4982:        eip +=eij[i][j][(int)age];
                   4983:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   4984:       }
                   4985:       fprintf(ficreseij,"%9.4f", eip );
                   4986:     }
                   4987:     fprintf(ficreseij,"\n");
                   4988:     
                   4989:   }
                   4990:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4991:   printf("\n");
                   4992:   fprintf(ficlog,"\n");
                   4993:   
                   4994: }
                   4995: 
1.235   ! brouard  4996:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  4997: 
                   4998: {
                   4999:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5000:      to initial status i, ei. .
1.126     brouard  5001:   */
                   5002:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5003:   int nhstepma, nstepma; /* Decreasing with age */
                   5004:   double age, agelim, hf;
                   5005:   double ***p3matp, ***p3matm, ***varhe;
                   5006:   double **dnewm,**doldm;
                   5007:   double *xp, *xm;
                   5008:   double **gp, **gm;
                   5009:   double ***gradg, ***trgradg;
                   5010:   int theta;
                   5011: 
                   5012:   double eip, vip;
                   5013: 
                   5014:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5015:   xp=vector(1,npar);
                   5016:   xm=vector(1,npar);
                   5017:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5018:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5019:   
                   5020:   pstamp(ficresstdeij);
                   5021:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5022:   fprintf(ficresstdeij,"# Age");
                   5023:   for(i=1; i<=nlstate;i++){
                   5024:     for(j=1; j<=nlstate;j++)
                   5025:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5026:     fprintf(ficresstdeij," e%1d. ",i);
                   5027:   }
                   5028:   fprintf(ficresstdeij,"\n");
                   5029: 
                   5030:   pstamp(ficrescveij);
                   5031:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5032:   fprintf(ficrescveij,"# Age");
                   5033:   for(i=1; i<=nlstate;i++)
                   5034:     for(j=1; j<=nlstate;j++){
                   5035:       cptj= (j-1)*nlstate+i;
                   5036:       for(i2=1; i2<=nlstate;i2++)
                   5037:        for(j2=1; j2<=nlstate;j2++){
                   5038:          cptj2= (j2-1)*nlstate+i2;
                   5039:          if(cptj2 <= cptj)
                   5040:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5041:        }
                   5042:     }
                   5043:   fprintf(ficrescveij,"\n");
                   5044:   
                   5045:   if(estepm < stepm){
                   5046:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5047:   }
                   5048:   else  hstepm=estepm;   
                   5049:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5050:    * This is mainly to measure the difference between two models: for example
                   5051:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5052:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5053:    * progression in between and thus overestimating or underestimating according
                   5054:    * to the curvature of the survival function. If, for the same date, we 
                   5055:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5056:    * to compare the new estimate of Life expectancy with the same linear 
                   5057:    * hypothesis. A more precise result, taking into account a more precise
                   5058:    * curvature will be obtained if estepm is as small as stepm. */
                   5059: 
                   5060:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5061:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5062:      nhstepm is the number of hstepm from age to agelim 
                   5063:      nstepm is the number of stepm from age to agelin. 
                   5064:      Look at hpijx to understand the reason of that which relies in memory size
                   5065:      and note for a fixed period like estepm months */
                   5066:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5067:      survival function given by stepm (the optimization length). Unfortunately it
                   5068:      means that if the survival funtion is printed only each two years of age and if
                   5069:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5070:      results. So we changed our mind and took the option of the best precision.
                   5071:   */
                   5072:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5073: 
                   5074:   /* If stepm=6 months */
                   5075:   /* nhstepm age range expressed in number of stepm */
                   5076:   agelim=AGESUP;
                   5077:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5078:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5079:   /* if (stepm >= YEARM) hstepm=1;*/
                   5080:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5081:   
                   5082:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5083:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5084:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5085:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5086:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5087:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5088: 
                   5089:   for (age=bage; age<=fage; age ++){ 
                   5090:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5091:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5092:     /* if (stepm >= YEARM) hstepm=1;*/
                   5093:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5094:                
1.126     brouard  5095:     /* If stepm=6 months */
                   5096:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5097:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5098:     
                   5099:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5100:                
1.126     brouard  5101:     /* Computing  Variances of health expectancies */
                   5102:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5103:        decrease memory allocation */
                   5104:     for(theta=1; theta <=npar; theta++){
                   5105:       for(i=1; i<=npar; i++){ 
1.222     brouard  5106:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5107:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5108:       }
1.235   ! brouard  5109:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
        !          5110:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5111:                        
1.126     brouard  5112:       for(j=1; j<= nlstate; j++){
1.222     brouard  5113:        for(i=1; i<=nlstate; i++){
                   5114:          for(h=0; h<=nhstepm-1; h++){
                   5115:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5116:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5117:          }
                   5118:        }
1.126     brouard  5119:       }
1.218     brouard  5120:                        
1.126     brouard  5121:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5122:        for(h=0; h<=nhstepm-1; h++){
                   5123:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5124:        }
1.126     brouard  5125:     }/* End theta */
                   5126:     
                   5127:     
                   5128:     for(h=0; h<=nhstepm-1; h++)
                   5129:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5130:        for(theta=1; theta <=npar; theta++)
                   5131:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5132:     
1.218     brouard  5133:                
1.222     brouard  5134:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5135:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5136:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5137:                
1.222     brouard  5138:     printf("%d|",(int)age);fflush(stdout);
                   5139:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5140:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5141:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5142:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5143:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5144:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5145:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5146:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5147:       }
                   5148:     }
1.218     brouard  5149:                
1.126     brouard  5150:     /* Computing expectancies */
1.235   ! brouard  5151:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5152:     for(i=1; i<=nlstate;i++)
                   5153:       for(j=1; j<=nlstate;j++)
1.222     brouard  5154:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5155:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5156:                                        
1.222     brouard  5157:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5158:                                        
1.222     brouard  5159:        }
1.218     brouard  5160:                
1.126     brouard  5161:     fprintf(ficresstdeij,"%3.0f",age );
                   5162:     for(i=1; i<=nlstate;i++){
                   5163:       eip=0.;
                   5164:       vip=0.;
                   5165:       for(j=1; j<=nlstate;j++){
1.222     brouard  5166:        eip += eij[i][j][(int)age];
                   5167:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5168:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5169:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5170:       }
                   5171:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5172:     }
                   5173:     fprintf(ficresstdeij,"\n");
1.218     brouard  5174:                
1.126     brouard  5175:     fprintf(ficrescveij,"%3.0f",age );
                   5176:     for(i=1; i<=nlstate;i++)
                   5177:       for(j=1; j<=nlstate;j++){
1.222     brouard  5178:        cptj= (j-1)*nlstate+i;
                   5179:        for(i2=1; i2<=nlstate;i2++)
                   5180:          for(j2=1; j2<=nlstate;j2++){
                   5181:            cptj2= (j2-1)*nlstate+i2;
                   5182:            if(cptj2 <= cptj)
                   5183:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5184:          }
1.126     brouard  5185:       }
                   5186:     fprintf(ficrescveij,"\n");
1.218     brouard  5187:                
1.126     brouard  5188:   }
                   5189:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5190:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5191:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5192:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5193:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5194:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5195:   printf("\n");
                   5196:   fprintf(ficlog,"\n");
1.218     brouard  5197:        
1.126     brouard  5198:   free_vector(xm,1,npar);
                   5199:   free_vector(xp,1,npar);
                   5200:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5201:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5202:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5203: }
1.218     brouard  5204:  
1.126     brouard  5205: /************ Variance ******************/
1.235   ! brouard  5206:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5207:  {
                   5208:    /* Variance of health expectancies */
                   5209:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5210:    /* double **newm;*/
                   5211:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5212:   
                   5213:    /* int movingaverage(); */
                   5214:    double **dnewm,**doldm;
                   5215:    double **dnewmp,**doldmp;
                   5216:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5217:    int k;
                   5218:    double *xp;
                   5219:    double **gp, **gm;  /* for var eij */
                   5220:    double ***gradg, ***trgradg; /*for var eij */
                   5221:    double **gradgp, **trgradgp; /* for var p point j */
                   5222:    double *gpp, *gmp; /* for var p point j */
                   5223:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5224:    double ***p3mat;
                   5225:    double age,agelim, hf;
                   5226:    /* double ***mobaverage; */
                   5227:    int theta;
                   5228:    char digit[4];
                   5229:    char digitp[25];
                   5230: 
                   5231:    char fileresprobmorprev[FILENAMELENGTH];
                   5232: 
                   5233:    if(popbased==1){
                   5234:      if(mobilav!=0)
                   5235:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5236:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5237:    }
                   5238:    else 
                   5239:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5240: 
1.218     brouard  5241:    /* if (mobilav!=0) { */
                   5242:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5243:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5244:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5245:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5246:    /*   } */
                   5247:    /* } */
                   5248: 
                   5249:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5250:    sprintf(digit,"%-d",ij);
                   5251:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5252:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5253:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5254:    strcat(fileresprobmorprev,fileresu);
                   5255:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5256:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5257:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5258:    }
                   5259:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5260:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5261:    pstamp(ficresprobmorprev);
                   5262:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
                   5263:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5264:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5265:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5266:      for(i=1; i<=nlstate;i++)
                   5267:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5268:    }  
                   5269:    fprintf(ficresprobmorprev,"\n");
                   5270:   
                   5271:    fprintf(ficgp,"\n# Routine varevsij");
                   5272:    fprintf(ficgp,"\nunset title \n");
                   5273:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5274:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5275:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5276:    /*   } */
                   5277:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5278:    pstamp(ficresvij);
                   5279:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5280:    if(popbased==1)
                   5281:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5282:    else
                   5283:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5284:    fprintf(ficresvij,"# Age");
                   5285:    for(i=1; i<=nlstate;i++)
                   5286:      for(j=1; j<=nlstate;j++)
                   5287:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5288:    fprintf(ficresvij,"\n");
                   5289: 
                   5290:    xp=vector(1,npar);
                   5291:    dnewm=matrix(1,nlstate,1,npar);
                   5292:    doldm=matrix(1,nlstate,1,nlstate);
                   5293:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5294:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5295: 
                   5296:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5297:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5298:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5299:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5300:   
1.218     brouard  5301:    if(estepm < stepm){
                   5302:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5303:    }
                   5304:    else  hstepm=estepm;   
                   5305:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5306:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5307:       nhstepm is the number of hstepm from age to agelim 
                   5308:       nstepm is the number of stepm from age to agelim. 
                   5309:       Look at function hpijx to understand why because of memory size limitations, 
                   5310:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5311:       survival function given by stepm (the optimization length). Unfortunately it
                   5312:       means that if the survival funtion is printed every two years of age and if
                   5313:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5314:       results. So we changed our mind and took the option of the best precision.
                   5315:    */
                   5316:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5317:    agelim = AGESUP;
                   5318:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5319:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5320:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5321:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5322:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5323:      gp=matrix(0,nhstepm,1,nlstate);
                   5324:      gm=matrix(0,nhstepm,1,nlstate);
                   5325:                
                   5326:                
                   5327:      for(theta=1; theta <=npar; theta++){
                   5328:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5329:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5330:        }
                   5331:                        
1.235   ! brouard  5332:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nresult);
1.218     brouard  5333:                        
                   5334:        if (popbased==1) {
                   5335:         if(mobilav ==0){
                   5336:           for(i=1; i<=nlstate;i++)
                   5337:             prlim[i][i]=probs[(int)age][i][ij];
                   5338:         }else{ /* mobilav */ 
                   5339:           for(i=1; i<=nlstate;i++)
                   5340:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5341:         }
                   5342:        }
                   5343:                        
1.235   ! brouard  5344:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5345:        for(j=1; j<= nlstate; j++){
                   5346:         for(h=0; h<=nhstepm; h++){
                   5347:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5348:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5349:         }
                   5350:        }
                   5351:        /* Next for computing probability of death (h=1 means
                   5352:          computed over hstepm matrices product = hstepm*stepm months) 
                   5353:          as a weighted average of prlim.
                   5354:        */
                   5355:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5356:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5357:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5358:        }    
                   5359:        /* end probability of death */
                   5360:                        
                   5361:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5362:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5363:                        
1.235   ! brouard  5364:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nresult);
1.218     brouard  5365:                        
                   5366:        if (popbased==1) {
                   5367:         if(mobilav ==0){
                   5368:           for(i=1; i<=nlstate;i++)
                   5369:             prlim[i][i]=probs[(int)age][i][ij];
                   5370:         }else{ /* mobilav */ 
                   5371:           for(i=1; i<=nlstate;i++)
                   5372:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5373:         }
                   5374:        }
                   5375:                        
1.235   ! brouard  5376:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5377:                        
                   5378:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5379:         for(h=0; h<=nhstepm; h++){
                   5380:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5381:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5382:         }
                   5383:        }
                   5384:        /* This for computing probability of death (h=1 means
                   5385:          computed over hstepm matrices product = hstepm*stepm months) 
                   5386:          as a weighted average of prlim.
                   5387:        */
                   5388:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5389:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5390:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5391:        }    
                   5392:        /* end probability of death */
                   5393:                        
                   5394:        for(j=1; j<= nlstate; j++) /* vareij */
                   5395:         for(h=0; h<=nhstepm; h++){
                   5396:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5397:         }
                   5398:                        
                   5399:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5400:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5401:        }
                   5402:                        
                   5403:      } /* End theta */
                   5404:                
                   5405:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5406:                
                   5407:      for(h=0; h<=nhstepm; h++) /* veij */
                   5408:        for(j=1; j<=nlstate;j++)
                   5409:         for(theta=1; theta <=npar; theta++)
                   5410:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5411:                
                   5412:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5413:        for(theta=1; theta <=npar; theta++)
                   5414:         trgradgp[j][theta]=gradgp[theta][j];
                   5415:                
                   5416:                
                   5417:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5418:      for(i=1;i<=nlstate;i++)
                   5419:        for(j=1;j<=nlstate;j++)
                   5420:         vareij[i][j][(int)age] =0.;
                   5421:                
                   5422:      for(h=0;h<=nhstepm;h++){
                   5423:        for(k=0;k<=nhstepm;k++){
                   5424:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5425:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5426:         for(i=1;i<=nlstate;i++)
                   5427:           for(j=1;j<=nlstate;j++)
                   5428:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5429:        }
                   5430:      }
                   5431:                
                   5432:      /* pptj */
                   5433:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5434:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5435:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5436:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5437:         varppt[j][i]=doldmp[j][i];
                   5438:      /* end ppptj */
                   5439:      /*  x centered again */
                   5440:                
1.235   ! brouard  5441:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nresult);
1.218     brouard  5442:                
                   5443:      if (popbased==1) {
                   5444:        if(mobilav ==0){
                   5445:         for(i=1; i<=nlstate;i++)
                   5446:           prlim[i][i]=probs[(int)age][i][ij];
                   5447:        }else{ /* mobilav */ 
                   5448:         for(i=1; i<=nlstate;i++)
                   5449:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5450:        }
                   5451:      }
                   5452:                
                   5453:      /* This for computing probability of death (h=1 means
                   5454:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5455:        as a weighted average of prlim.
                   5456:      */
1.235   ! brouard  5457:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5458:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5459:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5460:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5461:      }    
                   5462:      /* end probability of death */
                   5463:                
                   5464:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5465:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5466:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5467:        for(i=1; i<=nlstate;i++){
                   5468:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5469:        }
                   5470:      } 
                   5471:      fprintf(ficresprobmorprev,"\n");
                   5472:                
                   5473:      fprintf(ficresvij,"%.0f ",age );
                   5474:      for(i=1; i<=nlstate;i++)
                   5475:        for(j=1; j<=nlstate;j++){
                   5476:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5477:        }
                   5478:      fprintf(ficresvij,"\n");
                   5479:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5480:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5481:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5482:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5483:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5484:    } /* End age */
                   5485:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5486:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5487:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5488:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5489:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5490:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5491:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5492:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5493:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5494:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5495:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5496:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5497:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5498:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5499:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5500:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5501:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5502:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5503:     */
1.218     brouard  5504:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5505:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5506: 
1.218     brouard  5507:    free_vector(xp,1,npar);
                   5508:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5509:    free_matrix(dnewm,1,nlstate,1,npar);
                   5510:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5511:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5512:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5513:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5514:    fclose(ficresprobmorprev);
                   5515:    fflush(ficgp);
                   5516:    fflush(fichtm); 
                   5517:  }  /* end varevsij */
1.126     brouard  5518: 
                   5519: /************ Variance of prevlim ******************/
1.235   ! brouard  5520:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5521: {
1.205     brouard  5522:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5523:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5524: 
1.126     brouard  5525:   double **dnewm,**doldm;
                   5526:   int i, j, nhstepm, hstepm;
                   5527:   double *xp;
                   5528:   double *gp, *gm;
                   5529:   double **gradg, **trgradg;
1.208     brouard  5530:   double **mgm, **mgp;
1.126     brouard  5531:   double age,agelim;
                   5532:   int theta;
                   5533:   
                   5534:   pstamp(ficresvpl);
                   5535:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
                   5536:   fprintf(ficresvpl,"# Age");
                   5537:   for(i=1; i<=nlstate;i++)
                   5538:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5539:   fprintf(ficresvpl,"\n");
                   5540: 
                   5541:   xp=vector(1,npar);
                   5542:   dnewm=matrix(1,nlstate,1,npar);
                   5543:   doldm=matrix(1,nlstate,1,nlstate);
                   5544:   
                   5545:   hstepm=1*YEARM; /* Every year of age */
                   5546:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5547:   agelim = AGESUP;
                   5548:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5549:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5550:     if (stepm >= YEARM) hstepm=1;
                   5551:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5552:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5553:     mgp=matrix(1,npar,1,nlstate);
                   5554:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5555:     gp=vector(1,nlstate);
                   5556:     gm=vector(1,nlstate);
                   5557: 
                   5558:     for(theta=1; theta <=npar; theta++){
                   5559:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5560:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5561:       }
1.209     brouard  5562:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235   ! brouard  5563:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5564:       else
1.235   ! brouard  5565:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5566:       for(i=1;i<=nlstate;i++){
1.126     brouard  5567:        gp[i] = prlim[i][i];
1.208     brouard  5568:        mgp[theta][i] = prlim[i][i];
                   5569:       }
1.126     brouard  5570:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5571:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5572:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235   ! brouard  5573:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5574:       else
1.235   ! brouard  5575:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5576:       for(i=1;i<=nlstate;i++){
1.126     brouard  5577:        gm[i] = prlim[i][i];
1.208     brouard  5578:        mgm[theta][i] = prlim[i][i];
                   5579:       }
1.126     brouard  5580:       for(i=1;i<=nlstate;i++)
                   5581:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5582:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5583:     } /* End theta */
                   5584: 
                   5585:     trgradg =matrix(1,nlstate,1,npar);
                   5586: 
                   5587:     for(j=1; j<=nlstate;j++)
                   5588:       for(theta=1; theta <=npar; theta++)
                   5589:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5590:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5591:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5592:     /*   for(j=1; j<=nlstate;j++){ */
                   5593:     /*         printf(" %d ",j); */
                   5594:     /*         for(theta=1; theta <=npar; theta++) */
                   5595:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5596:     /*         printf("\n "); */
                   5597:     /*   } */
                   5598:     /* } */
                   5599:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5600:     /*   printf("\n gradg %d ",(int)age); */
                   5601:     /*   for(j=1; j<=nlstate;j++){ */
                   5602:     /*         printf("%d ",j); */
                   5603:     /*         for(theta=1; theta <=npar; theta++) */
                   5604:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5605:     /*         printf("\n "); */
                   5606:     /*   } */
                   5607:     /* } */
1.126     brouard  5608: 
                   5609:     for(i=1;i<=nlstate;i++)
                   5610:       varpl[i][(int)age] =0.;
1.209     brouard  5611:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5612:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5613:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5614:     }else{
1.126     brouard  5615:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5616:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5617:     }
1.126     brouard  5618:     for(i=1;i<=nlstate;i++)
                   5619:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5620: 
                   5621:     fprintf(ficresvpl,"%.0f ",age );
                   5622:     for(i=1; i<=nlstate;i++)
                   5623:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   5624:     fprintf(ficresvpl,"\n");
                   5625:     free_vector(gp,1,nlstate);
                   5626:     free_vector(gm,1,nlstate);
1.208     brouard  5627:     free_matrix(mgm,1,npar,1,nlstate);
                   5628:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  5629:     free_matrix(gradg,1,npar,1,nlstate);
                   5630:     free_matrix(trgradg,1,nlstate,1,npar);
                   5631:   } /* End age */
                   5632: 
                   5633:   free_vector(xp,1,npar);
                   5634:   free_matrix(doldm,1,nlstate,1,npar);
                   5635:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   5636: 
                   5637: }
                   5638: 
                   5639: /************ Variance of one-step probabilities  ******************/
                   5640: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  5641:  {
                   5642:    int i, j=0,  k1, l1, tj;
                   5643:    int k2, l2, j1,  z1;
                   5644:    int k=0, l;
                   5645:    int first=1, first1, first2;
                   5646:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   5647:    double **dnewm,**doldm;
                   5648:    double *xp;
                   5649:    double *gp, *gm;
                   5650:    double **gradg, **trgradg;
                   5651:    double **mu;
                   5652:    double age, cov[NCOVMAX+1];
                   5653:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   5654:    int theta;
                   5655:    char fileresprob[FILENAMELENGTH];
                   5656:    char fileresprobcov[FILENAMELENGTH];
                   5657:    char fileresprobcor[FILENAMELENGTH];
                   5658:    double ***varpij;
                   5659: 
                   5660:    strcpy(fileresprob,"PROB_"); 
                   5661:    strcat(fileresprob,fileres);
                   5662:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   5663:      printf("Problem with resultfile: %s\n", fileresprob);
                   5664:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   5665:    }
                   5666:    strcpy(fileresprobcov,"PROBCOV_"); 
                   5667:    strcat(fileresprobcov,fileresu);
                   5668:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   5669:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   5670:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   5671:    }
                   5672:    strcpy(fileresprobcor,"PROBCOR_"); 
                   5673:    strcat(fileresprobcor,fileresu);
                   5674:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   5675:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   5676:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   5677:    }
                   5678:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5679:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5680:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5681:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5682:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5683:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5684:    pstamp(ficresprob);
                   5685:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   5686:    fprintf(ficresprob,"# Age");
                   5687:    pstamp(ficresprobcov);
                   5688:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   5689:    fprintf(ficresprobcov,"# Age");
                   5690:    pstamp(ficresprobcor);
                   5691:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   5692:    fprintf(ficresprobcor,"# Age");
1.126     brouard  5693: 
                   5694: 
1.222     brouard  5695:    for(i=1; i<=nlstate;i++)
                   5696:      for(j=1; j<=(nlstate+ndeath);j++){
                   5697:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   5698:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   5699:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   5700:      }  
                   5701:    /* fprintf(ficresprob,"\n");
                   5702:       fprintf(ficresprobcov,"\n");
                   5703:       fprintf(ficresprobcor,"\n");
                   5704:    */
                   5705:    xp=vector(1,npar);
                   5706:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5707:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5708:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   5709:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   5710:    first=1;
                   5711:    fprintf(ficgp,"\n# Routine varprob");
                   5712:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   5713:    fprintf(fichtm,"\n");
                   5714: 
                   5715:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   5716:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   5717:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  5718: and drawn. It helps understanding how is the covariance between two incidences.\
                   5719:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  5720:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  5721: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   5722: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   5723: standard deviations wide on each axis. <br>\
                   5724:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   5725:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   5726: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   5727: 
1.222     brouard  5728:    cov[1]=1;
                   5729:    /* tj=cptcoveff; */
1.225     brouard  5730:    tj = (int) pow(2,cptcoveff);
1.222     brouard  5731:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   5732:    j1=0;
1.224     brouard  5733:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  5734:      if  (cptcovn>0) {
                   5735:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  5736:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5737:        fprintf(ficresprob, "**********\n#\n");
                   5738:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  5739:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5740:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  5741:                        
1.222     brouard  5742:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  5743:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5744:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  5745:                        
                   5746:                        
1.222     brouard  5747:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  5748:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5749:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  5750:                        
1.222     brouard  5751:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  5752:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5753:        fprintf(ficresprobcor, "**********\n#");    
                   5754:        if(invalidvarcomb[j1]){
                   5755:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   5756:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   5757:         continue;
                   5758:        }
                   5759:      }
                   5760:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   5761:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5762:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   5763:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   5764:      for (age=bage; age<=fage; age ++){ 
                   5765:        cov[2]=age;
                   5766:        if(nagesqr==1)
                   5767:         cov[3]= age*age;
                   5768:        for (k=1; k<=cptcovn;k++) {
                   5769:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   5770:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   5771:                                                                    * 1  1 1 1 1
                   5772:                                                                    * 2  2 1 1 1
                   5773:                                                                    * 3  1 2 1 1
                   5774:                                                                    */
                   5775:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   5776:        }
                   5777:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   5778:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   5779:        for (k=1; k<=cptcovprod;k++)
                   5780:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  5781:                        
                   5782:                        
1.222     brouard  5783:        for(theta=1; theta <=npar; theta++){
                   5784:         for(i=1; i<=npar; i++)
                   5785:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  5786:                                
1.222     brouard  5787:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  5788:                                
1.222     brouard  5789:         k=0;
                   5790:         for(i=1; i<= (nlstate); i++){
                   5791:           for(j=1; j<=(nlstate+ndeath);j++){
                   5792:             k=k+1;
                   5793:             gp[k]=pmmij[i][j];
                   5794:           }
                   5795:         }
1.220     brouard  5796:                                
1.222     brouard  5797:         for(i=1; i<=npar; i++)
                   5798:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  5799:                                
1.222     brouard  5800:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   5801:         k=0;
                   5802:         for(i=1; i<=(nlstate); i++){
                   5803:           for(j=1; j<=(nlstate+ndeath);j++){
                   5804:             k=k+1;
                   5805:             gm[k]=pmmij[i][j];
                   5806:           }
                   5807:         }
1.220     brouard  5808:                                
1.222     brouard  5809:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   5810:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   5811:        }
1.126     brouard  5812: 
1.222     brouard  5813:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   5814:         for(theta=1; theta <=npar; theta++)
                   5815:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  5816:                        
1.222     brouard  5817:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   5818:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  5819:                        
1.222     brouard  5820:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  5821:                        
1.222     brouard  5822:        k=0;
                   5823:        for(i=1; i<=(nlstate); i++){
                   5824:         for(j=1; j<=(nlstate+ndeath);j++){
                   5825:           k=k+1;
                   5826:           mu[k][(int) age]=pmmij[i][j];
                   5827:         }
                   5828:        }
                   5829:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   5830:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   5831:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  5832:                        
1.222     brouard  5833:        /*printf("\n%d ",(int)age);
                   5834:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5835:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5836:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5837:         }*/
1.220     brouard  5838:                        
1.222     brouard  5839:        fprintf(ficresprob,"\n%d ",(int)age);
                   5840:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   5841:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  5842:                        
1.222     brouard  5843:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   5844:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   5845:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5846:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   5847:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   5848:        }
                   5849:        i=0;
                   5850:        for (k=1; k<=(nlstate);k++){
                   5851:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   5852:           i++;
                   5853:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   5854:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   5855:           for (j=1; j<=i;j++){
                   5856:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   5857:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   5858:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   5859:           }
                   5860:         }
                   5861:        }/* end of loop for state */
                   5862:      } /* end of loop for age */
                   5863:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   5864:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   5865:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   5866:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   5867:     
                   5868:      /* Confidence intervalle of pij  */
                   5869:      /*
                   5870:        fprintf(ficgp,"\nunset parametric;unset label");
                   5871:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   5872:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   5873:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   5874:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   5875:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   5876:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   5877:      */
                   5878:                
                   5879:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   5880:      first1=1;first2=2;
                   5881:      for (k2=1; k2<=(nlstate);k2++){
                   5882:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   5883:         if(l2==k2) continue;
                   5884:         j=(k2-1)*(nlstate+ndeath)+l2;
                   5885:         for (k1=1; k1<=(nlstate);k1++){
                   5886:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   5887:             if(l1==k1) continue;
                   5888:             i=(k1-1)*(nlstate+ndeath)+l1;
                   5889:             if(i<=j) continue;
                   5890:             for (age=bage; age<=fage; age ++){ 
                   5891:               if ((int)age %5==0){
                   5892:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   5893:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   5894:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   5895:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   5896:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   5897:                 c12=cv12/sqrt(v1*v2);
                   5898:                 /* Computing eigen value of matrix of covariance */
                   5899:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   5900:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   5901:                 if ((lc2 <0) || (lc1 <0) ){
                   5902:                   if(first2==1){
                   5903:                     first1=0;
                   5904:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   5905:                   }
                   5906:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   5907:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   5908:                   /* lc2=fabs(lc2); */
                   5909:                 }
1.220     brouard  5910:                                                                
1.222     brouard  5911:                 /* Eigen vectors */
                   5912:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   5913:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   5914:                 v21=(lc1-v1)/cv12*v11;
                   5915:                 v12=-v21;
                   5916:                 v22=v11;
                   5917:                 tnalp=v21/v11;
                   5918:                 if(first1==1){
                   5919:                   first1=0;
                   5920:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   5921:                 }
                   5922:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   5923:                 /*printf(fignu*/
                   5924:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   5925:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   5926:                 if(first==1){
                   5927:                   first=0;
                   5928:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   5929:                   fprintf(ficgp,"\nset parametric;unset label");
                   5930:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   5931:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   5932:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  5933:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  5934: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  5935:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   5936:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5937:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5938:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   5939:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5940:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   5941:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   5942:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   5943:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   5944:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   5945:                 }else{
                   5946:                   first=0;
                   5947:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   5948:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   5949:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   5950:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   5951:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   5952:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   5953:                 }/* if first */
                   5954:               } /* age mod 5 */
                   5955:             } /* end loop age */
                   5956:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5957:             first=1;
                   5958:           } /*l12 */
                   5959:         } /* k12 */
                   5960:        } /*l1 */
                   5961:      }/* k1 */
                   5962:    }  /* loop on combination of covariates j1 */
                   5963:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   5964:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   5965:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5966:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   5967:    free_vector(xp,1,npar);
                   5968:    fclose(ficresprob);
                   5969:    fclose(ficresprobcov);
                   5970:    fclose(ficresprobcor);
                   5971:    fflush(ficgp);
                   5972:    fflush(fichtmcov);
                   5973:  }
1.126     brouard  5974: 
                   5975: 
                   5976: /******************* Printing html file ***********/
1.201     brouard  5977: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  5978:                  int lastpass, int stepm, int weightopt, char model[],\
                   5979:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  5980:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  5981:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   5982:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.126     brouard  5983:   int jj1, k1, i1, cpt;
                   5984: 
                   5985:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   5986:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   5987: </ul>");
1.214     brouard  5988:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   5989:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   5990:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   5991:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  5992:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   5993:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  5994:    fprintf(fichtm,"\
                   5995:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  5996:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  5997:    fprintf(fichtm,"\
1.217     brouard  5998:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   5999:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6000:    fprintf(fichtm,"\
1.126     brouard  6001:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6002:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6003:    fprintf(fichtm,"\
1.217     brouard  6004:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6005:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6006:    fprintf(fichtm,"\
1.211     brouard  6007:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6008:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6009:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6010:    if(prevfcast==1){
                   6011:      fprintf(fichtm,"\
                   6012:  - Prevalence projections by age and states:                           \
1.201     brouard  6013:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6014:    }
1.126     brouard  6015: 
1.222     brouard  6016:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6017: 
1.225     brouard  6018:    m=pow(2,cptcoveff);
1.222     brouard  6019:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6020: 
1.222     brouard  6021:    jj1=0;
                   6022:    for(k1=1; k1<=m;k1++){
1.220     brouard  6023: 
1.222     brouard  6024:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6025:      jj1++;
                   6026:      if (cptcovn > 0) {
                   6027:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6028:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.222     brouard  6029:         fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
                   6030:         printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout);
                   6031:        }
1.230     brouard  6032:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6033:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6034:        if(invalidvarcomb[k1]){
                   6035:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6036:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6037:         continue;
                   6038:        }
                   6039:      }
                   6040:      /* aij, bij */
                   6041:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1.svg\">%s_%d-1.svg</a><br> \
1.211     brouard  6042: <img src=\"%s_%d-1.svg\">",model,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
1.222     brouard  6043:      /* Pij */
                   6044:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2.svg\">%s_%d-2.svg</a><br> \
1.201     brouard  6045: <img src=\"%s_%d-2.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);     
1.222     brouard  6046:      /* Quasi-incidences */
                   6047:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6048:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6049:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
                   6050: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3.svg\">%s_%d-3.svg</a><br> \
1.201     brouard  6051: <img src=\"%s_%d-3.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); 
1.222     brouard  6052:      /* Survival functions (period) in state j */
                   6053:      for(cpt=1; cpt<=nlstate;cpt++){
                   6054:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
1.201     brouard  6055: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1);
1.222     brouard  6056:      }
                   6057:      /* State specific survival functions (period) */
                   6058:      for(cpt=1; cpt<=nlstate;cpt++){
                   6059:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6060:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.201     brouard  6061:  <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> <img src=\"%s_%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1);
1.222     brouard  6062:      }
                   6063:      /* Period (stable) prevalence in each health state */
                   6064:      for(cpt=1; cpt<=nlstate;cpt++){
                   6065:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a><br> \
1.201     brouard  6066: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1);
1.222     brouard  6067:      }
                   6068:      if(backcast==1){
                   6069:        /* Period (stable) back prevalence in each health state */
                   6070:        for(cpt=1; cpt<=nlstate;cpt++){
                   6071:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a><br> \
1.217     brouard  6072: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1);
1.222     brouard  6073:        }
1.217     brouard  6074:      }
1.222     brouard  6075:      if(prevfcast==1){
                   6076:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6077:        for(cpt=1; cpt<=nlstate;cpt++){
                   6078:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
1.213     brouard  6079: <img src=\"%s_%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1);
1.222     brouard  6080:        }
                   6081:      }
1.220     brouard  6082:         
1.222     brouard  6083:      for(cpt=1; cpt<=nlstate;cpt++) {
                   6084:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d%d.svg\">%s_%d%d.svg</a> <br> \
1.201     brouard  6085: <img src=\"%s_%d%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1);
1.222     brouard  6086:      }
                   6087:      /* } /\* end i1 *\/ */
                   6088:    }/* End k1 */
                   6089:    fprintf(fichtm,"</ul>");
1.126     brouard  6090: 
1.222     brouard  6091:    fprintf(fichtm,"\
1.126     brouard  6092: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6093:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6094:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6095: But because parameters are usually highly correlated (a higher incidence of disability \
                   6096: and a higher incidence of recovery can give very close observed transition) it might \
                   6097: be very useful to look not only at linear confidence intervals estimated from the \
                   6098: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6099: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6100: covariance matrix of the one-step probabilities. \
                   6101: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6102: 
1.222     brouard  6103:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6104:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6105:    fprintf(fichtm,"\
1.126     brouard  6106:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6107:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6108: 
1.222     brouard  6109:    fprintf(fichtm,"\
1.126     brouard  6110:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6111:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6112:    fprintf(fichtm,"\
1.126     brouard  6113:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6114:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6115:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6116:    fprintf(fichtm,"\
1.126     brouard  6117:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6118:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6119:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6120:    fprintf(fichtm,"\
1.128     brouard  6121:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6122:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6123:    fprintf(fichtm,"\
1.128     brouard  6124:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6125:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6126:    fprintf(fichtm,"\
1.126     brouard  6127:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6128:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6129: 
                   6130: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6131: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6132: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6133: /*     <br>",fileres,fileres,fileres,fileres); */
                   6134: /*  else  */
                   6135: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6136:    fflush(fichtm);
                   6137:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6138: 
1.225     brouard  6139:    m=pow(2,cptcoveff);
1.222     brouard  6140:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6141: 
1.222     brouard  6142:    jj1=0;
                   6143:    for(k1=1; k1<=m;k1++){
                   6144:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6145:      jj1++;
1.126     brouard  6146:      if (cptcovn > 0) {
                   6147:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6148:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.222     brouard  6149:         fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
1.126     brouard  6150:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6151: 
1.222     brouard  6152:        if(invalidvarcomb[k1]){
                   6153:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6154:         continue;
                   6155:        }
1.126     brouard  6156:      }
                   6157:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6158:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
                   6159: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d.svg\"> %s_%d-%d.svg</a>\n <br>\
1.205     brouard  6160: <img src=\"%s_%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1);  
1.126     brouard  6161:      }
                   6162:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6163: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6164: true period expectancies (those weighted with period prevalences are also\
                   6165:  drawn in addition to the population based expectancies computed using\
1.218     brouard  6166:  observed and cahotic prevalences:  <a href=\"%s_%d.svg\">%s_%d.svg</a>\n<br>\
1.205     brouard  6167: <img src=\"%s_%d.svg\">",subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1);
1.222     brouard  6168:      /* } /\* end i1 *\/ */
                   6169:    }/* End k1 */
                   6170:    fprintf(fichtm,"</ul>");
                   6171:    fflush(fichtm);
1.126     brouard  6172: }
                   6173: 
                   6174: /******************* Gnuplot file **************/
1.223     brouard  6175: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6176: 
                   6177:   char dirfileres[132],optfileres[132];
1.223     brouard  6178:   char gplotcondition[132];
1.235   ! brouard  6179:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0,l=0;
1.211     brouard  6180:   int lv=0, vlv=0, kl=0;
1.130     brouard  6181:   int ng=0;
1.201     brouard  6182:   int vpopbased;
1.223     brouard  6183:   int ioffset; /* variable offset for columns */
1.235   ! brouard  6184:   int nres=0; /* Index of resultline */
1.219     brouard  6185: 
1.126     brouard  6186: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6187: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6188: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6189: /*   } */
                   6190: 
                   6191:   /*#ifdef windows */
                   6192:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6193:   /*#endif */
1.225     brouard  6194:   m=pow(2,cptcoveff);
1.126     brouard  6195: 
1.202     brouard  6196:   /* Contribution to likelihood */
                   6197:   /* Plot the probability implied in the likelihood */
1.223     brouard  6198:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6199:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6200:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6201:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6202: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6203:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6204: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6205:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6206:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6207:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6208:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6209:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6210:   for (i=1; i<= nlstate ; i ++) {
                   6211:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6212:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6213:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6214:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6215:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6216:     }
                   6217:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6218:   }
                   6219:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6220:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6221:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6222:   fprintf(ficgp,"\nset out;unset log\n");
                   6223:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6224: 
1.126     brouard  6225:   strcpy(dirfileres,optionfilefiname);
                   6226:   strcpy(optfileres,"vpl");
1.223     brouard  6227:   /* 1eme*/
1.211     brouard  6228:   for (cpt=1; cpt<= nlstate ; cpt ++) { /* For each live state */
1.235   ! brouard  6229:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          6230:     for (k1=1; k1<= m ; k1 ++) { /* For each valid combination of covariate */
        !          6231:     /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
        !          6232:       if(TKresult[nres]!= k1)
        !          6233:        continue;
        !          6234:       /* We are interested in selected combination by the resultline */
        !          6235:       printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt);
        !          6236:       fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.225     brouard  6237:       for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6238:        lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
1.223     brouard  6239:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6240:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6241:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6242:        vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6243:        /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.235   ! brouard  6244:        printf(" V%d=%d ",Tvaraff[k],vlv);
1.223     brouard  6245:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6246:       }
1.235   ! brouard  6247:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6248:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6249:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6250:       }        
        !          6251:       printf("\n#\n");
1.211     brouard  6252:       fprintf(ficgp,"\n#\n");
1.223     brouard  6253:       if(invalidvarcomb[k1]){
                   6254:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6255:        continue;
                   6256:       }
1.235   ! brouard  6257:       
1.223     brouard  6258:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1);
                   6259:       fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1);
                   6260:       fprintf(ficgp,"set xlabel \"Age\" \n\
1.235   ! brouard  6261: set ylabel \"Probability\" \n            \
        !          6262: set ter svg size 640, 480\n                                            \
1.201     brouard  6263: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1);
1.235   ! brouard  6264:       
1.223     brouard  6265:       for (i=1; i<= nlstate ; i ++) {
                   6266:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6267:        else        fprintf(ficgp," %%*lf (%%*lf)");
                   6268:       }
                   6269:       fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1);
                   6270:       for (i=1; i<= nlstate ; i ++) {
                   6271:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6272:        else fprintf(ficgp," %%*lf (%%*lf)");
                   6273:       } 
                   6274:       fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); 
                   6275:       for (i=1; i<= nlstate ; i ++) {
                   6276:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6277:        else fprintf(ficgp," %%*lf (%%*lf)");
                   6278:       }  
                   6279:       fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6280:       if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6281:        /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
                   6282:        fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1 */
1.225     brouard  6283:        if(cptcoveff ==0){
1.223     brouard  6284:          fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line ",  2+(cpt-1),  cpt );
                   6285:        }else{
                   6286:          kl=0;
1.225     brouard  6287:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6288:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
1.223     brouard  6289:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6290:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6291:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6292:            vlv= nbcode[Tvaraff[k]][lv];
                   6293:            kl++;
                   6294:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6295:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6296:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6297:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
1.225     brouard  6298:            if(k==cptcoveff){
1.227     brouard  6299:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   6300:                      4+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.223     brouard  6301:            }else{
                   6302:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6303:              kl++;
                   6304:            }
                   6305:          } /* end covariate */
                   6306:        } /* end if no covariate */
                   6307:       } /* end if backcast */
                   6308:       fprintf(ficgp,"\nset out \n");
1.201     brouard  6309:     } /* k1 */
                   6310:   } /* cpt */
1.235   ! brouard  6311: 
        !          6312:   
1.126     brouard  6313:   /*2 eme*/
                   6314:   for (k1=1; k1<= m ; k1 ++) { 
1.223     brouard  6315:     fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.235   ! brouard  6316:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.225     brouard  6317:     for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.235   ! brouard  6318:       if(TKresult[nres]!= k)
        !          6319:        continue;
1.225     brouard  6320:       lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6321:       /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6322:       /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6323:       /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6324:       vlv= nbcode[Tvaraff[k]][lv];
                   6325:       fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.235   ! brouard  6326:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6327:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6328:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6329:       }
1.223     brouard  6330:     }
                   6331:     fprintf(ficgp,"\n#\n");
                   6332:     if(invalidvarcomb[k1]){
                   6333:       fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6334:       continue;
                   6335:     }
1.219     brouard  6336:                        
1.223     brouard  6337:     fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1);
                   6338:     for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6339:       if(vpopbased==0)
                   6340:        fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6341:       else
                   6342:        fprintf(ficgp,"\nreplot ");
                   6343:       for (i=1; i<= nlstate+1 ; i ++) {
                   6344:        k=2*i;
                   6345:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6346:        for (j=1; j<= nlstate+1 ; j ++) {
                   6347:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6348:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6349:        }   
                   6350:        if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6351:        else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6352:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6353:        for (j=1; j<= nlstate+1 ; j ++) {
                   6354:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6355:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6356:        }   
                   6357:        fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6358:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6359:        for (j=1; j<= nlstate+1 ; j ++) {
                   6360:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6361:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6362:        }   
                   6363:        if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6364:        else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6365:       } /* state */
                   6366:     } /* vpopbased */
                   6367:     fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */
1.235   ! brouard  6368:   } /* k1 end 2 eme*/
1.219     brouard  6369:        
                   6370:        
1.126     brouard  6371:   /*3eme*/
                   6372:   for (k1=1; k1<= m ; k1 ++) { 
1.220     brouard  6373: 
1.126     brouard  6374:     for (cpt=1; cpt<= nlstate ; cpt ++) {
1.211     brouard  6375:       fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  cov=%d state=%d",k1, cpt);
1.235   ! brouard  6376:       for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.225     brouard  6377:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.235   ! brouard  6378:        if(TKresult[nres]!= k)
        !          6379:          continue;
1.225     brouard  6380:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6381:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6382:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6383:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6384:        vlv= nbcode[Tvaraff[k]][lv];
                   6385:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.235   ! brouard  6386:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6387:          printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6388:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6389:        }       
1.211     brouard  6390:       }
                   6391:       fprintf(ficgp,"\n#\n");
1.223     brouard  6392:       if(invalidvarcomb[k1]){
                   6393:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6394:        continue;
                   6395:       }
1.219     brouard  6396:                        
1.126     brouard  6397:       /*       k=2+nlstate*(2*cpt-2); */
                   6398:       k=2+(nlstate+1)*(cpt-1);
1.201     brouard  6399:       fprintf(ficgp,"\nset out \"%s_%d%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1);
1.199     brouard  6400:       fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6401: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.126     brouard  6402:       /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
1.223     brouard  6403:        for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6404:        fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6405:        fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6406:        for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6407:        fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6408:                                
1.126     brouard  6409:       */
                   6410:       for (i=1; i< nlstate ; i ++) {
1.223     brouard  6411:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6412:        /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6413:                                
1.126     brouard  6414:       } 
1.201     brouard  6415:       fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
1.126     brouard  6416:     }
                   6417:   }
                   6418:   
1.223     brouard  6419:   /* 4eme */
1.201     brouard  6420:   /* Survival functions (period) from state i in state j by initial state i */
                   6421:   for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
1.220     brouard  6422: 
1.201     brouard  6423:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.211     brouard  6424:       fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
1.225     brouard  6425:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6426:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6427:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6428:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6429:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6430:        vlv= nbcode[Tvaraff[k]][lv];
                   6431:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6432:       }
                   6433:       fprintf(ficgp,"\n#\n");
1.223     brouard  6434:       if(invalidvarcomb[k1]){
                   6435:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6436:        continue;
                   6437:       }
1.220     brouard  6438:                        
1.201     brouard  6439:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1);
                   6440:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
1.220     brouard  6441: set ter svg size 640, 480\n                                                                                                                                                                                    \
                   6442: unset log y\n                                                                                                                                                                                                                                          \
1.201     brouard  6443: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6444:       k=3;
1.201     brouard  6445:       for (i=1; i<= nlstate ; i ++){
1.223     brouard  6446:        if(i==1){
                   6447:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6448:        }else{
                   6449:          fprintf(ficgp,", '' ");
                   6450:        }
                   6451:        l=(nlstate+ndeath)*(i-1)+1;
                   6452:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6453:        for (j=2; j<= nlstate+ndeath ; j ++)
                   6454:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6455:        fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
1.201     brouard  6456:       } /* nlstate */
                   6457:       fprintf(ficgp,"\nset out\n");
                   6458:     } /* end cpt state*/ 
                   6459:   } /* end covariate */  
1.220     brouard  6460:        
                   6461: /* 5eme */
1.201     brouard  6462:   /* Survival functions (period) from state i in state j by final state j */
1.202     brouard  6463:   for (k1=1; k1<= m ; k1 ++) { /* For each covariate if any */
1.201     brouard  6464:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.223     brouard  6465:                        
1.201     brouard  6466:       fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
1.225     brouard  6467:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6468:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6469:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6470:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6471:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6472:        vlv= nbcode[Tvaraff[k]][lv];
                   6473:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6474:       }
                   6475:       fprintf(ficgp,"\n#\n");
1.223     brouard  6476:       if(invalidvarcomb[k1]){
1.227     brouard  6477:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6478:        continue;
1.223     brouard  6479:       }
1.227     brouard  6480:       
1.201     brouard  6481:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1);
                   6482:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
1.227     brouard  6483: set ter svg size 640, 480\n                                            \
                   6484: unset log y\n                                                          \
1.201     brouard  6485: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6486:       k=3;
1.201     brouard  6487:       for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
1.227     brouard  6488:        if(j==1)
                   6489:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6490:        else
                   6491:          fprintf(ficgp,", '' ");
                   6492:        l=(nlstate+ndeath)*(cpt-1) +j;
                   6493:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6494:        /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6495:        /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6496:        fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
1.201     brouard  6497:       } /* nlstate */
                   6498:       fprintf(ficgp,", '' ");
                   6499:       fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6500:       for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
1.227     brouard  6501:        l=(nlstate+ndeath)*(cpt-1) +j;
                   6502:        if(j < nlstate)
                   6503:          fprintf(ficgp,"$%d +",k+l);
                   6504:        else
                   6505:          fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
1.201     brouard  6506:       }
                   6507:       fprintf(ficgp,"\nset out\n");
                   6508:     } /* end cpt state*/ 
                   6509:   } /* end covariate */  
1.227     brouard  6510:   
1.220     brouard  6511: /* 6eme */
1.202     brouard  6512:   /* CV preval stable (period) for each covariate */
1.211     brouard  6513:   for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
1.153     brouard  6514:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6515:       
1.211     brouard  6516:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6517:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6518:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6519:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6520:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6521:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6522:        vlv= nbcode[Tvaraff[k]][lv];
                   6523:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6524:       }
                   6525:       fprintf(ficgp,"\n#\n");
1.223     brouard  6526:       if(invalidvarcomb[k1]){
1.227     brouard  6527:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6528:        continue;
1.223     brouard  6529:       }
1.227     brouard  6530:       
1.201     brouard  6531:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1);
1.126     brouard  6532:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.227     brouard  6533: set ter svg size 640, 480\n                                            \
                   6534: unset log y\n                                                          \
1.153     brouard  6535: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6536:       k=3; /* Offset */
1.153     brouard  6537:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6538:        if(i==1)
                   6539:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6540:        else
                   6541:          fprintf(ficgp,", '' ");
                   6542:        l=(nlstate+ndeath)*(i-1)+1;
                   6543:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6544:        for (j=2; j<= nlstate ; j ++)
                   6545:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6546:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6547:       } /* nlstate */
1.201     brouard  6548:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6549:     } /* end cpt state*/ 
                   6550:   } /* end covariate */  
1.227     brouard  6551:   
                   6552:   
1.220     brouard  6553: /* 7eme */
1.218     brouard  6554:   if(backcast == 1){
1.217     brouard  6555:     /* CV back preval stable (period) for each covariate */
1.218     brouard  6556:     for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
                   6557:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6558:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6559:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6560:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6561:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6562:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6563:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6564:          vlv= nbcode[Tvaraff[k]][lv];
                   6565:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6566:        }
                   6567:        fprintf(ficgp,"\n#\n");
                   6568:        if(invalidvarcomb[k1]){
                   6569:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6570:          continue;
                   6571:        }
                   6572:        
                   6573:        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1);
                   6574:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
                   6575: set ter svg size 640, 480\n                                            \
                   6576: unset log y\n                                                          \
1.218     brouard  6577: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6578:        k=3; /* Offset */
                   6579:        for (i=1; i<= nlstate ; i ++){
                   6580:          if(i==1)
                   6581:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   6582:          else
                   6583:            fprintf(ficgp,", '' ");
                   6584:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   6585:          l=(nlstate+ndeath)*(cpt-1)+1;
                   6586:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   6587:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   6588:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   6589:          /* for (j=2; j<= nlstate ; j ++) */
                   6590:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   6591:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   6592:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   6593:        } /* nlstate */
                   6594:        fprintf(ficgp,"\nset out\n");
1.218     brouard  6595:       } /* end cpt state*/ 
                   6596:     } /* end covariate */  
                   6597:   } /* End if backcast */
                   6598:   
1.223     brouard  6599:   /* 8eme */
1.218     brouard  6600:   if(prevfcast==1){
                   6601:     /* Projection from cross-sectional to stable (period) for each covariate */
                   6602:     
                   6603:     for (k1=1; k1<= m ; k1 ++) { /* For each covariate combination (1 to m=2**k), if any covariate is present */
1.211     brouard  6604:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6605:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   6606:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   6607:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6608:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6609:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6610:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6611:          vlv= nbcode[Tvaraff[k]][lv];
                   6612:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6613:        }
                   6614:        fprintf(ficgp,"\n#\n");
                   6615:        if(invalidvarcomb[k1]){
                   6616:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6617:          continue;
                   6618:        }
                   6619:        
                   6620:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
                   6621:        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1);
                   6622:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   6623: set ter svg size 640, 480\n                                            \
                   6624: unset log y\n                                                          \
1.219     brouard  6625: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6626:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   6627:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6628:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6629:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6630:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6631:          if(i==1){
                   6632:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   6633:          }else{
                   6634:            fprintf(ficgp,",\\\n '' ");
                   6635:          }
                   6636:          if(cptcoveff ==0){ /* No covariate */
                   6637:            ioffset=2; /* Age is in 2 */
                   6638:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6639:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6640:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6641:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6642:            fprintf(ficgp," u %d:(", ioffset); 
                   6643:            if(i==nlstate+1)
                   6644:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   6645:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6646:            else
                   6647:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   6648:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6649:          }else{ /* more than 2 covariates */
                   6650:            if(cptcoveff ==1){
                   6651:              ioffset=4; /* Age is in 4 */
                   6652:            }else{
                   6653:              ioffset=6; /* Age is in 6 */
                   6654:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6655:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   6656:            }   
                   6657:            fprintf(ficgp," u %d:(",ioffset); 
                   6658:            kl=0;
                   6659:            strcpy(gplotcondition,"(");
                   6660:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   6661:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   6662:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6663:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6664:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6665:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   6666:              kl++;
                   6667:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   6668:              kl++;
                   6669:              if(k <cptcoveff && cptcoveff>1)
                   6670:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   6671:            }
                   6672:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   6673:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6674:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6675:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6676:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6677:            if(i==nlstate+1){
                   6678:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   6679:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6680:            }else{
                   6681:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   6682:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6683:            }
                   6684:          } /* end if covariate */
                   6685:        } /* nlstate */
                   6686:        fprintf(ficgp,"\nset out\n");
1.223     brouard  6687:       } /* end cpt state*/
                   6688:     } /* end covariate */
                   6689:   } /* End if prevfcast */
1.227     brouard  6690:   
                   6691:   
1.223     brouard  6692:   /* proba elementaires */
                   6693:   fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n");
1.126     brouard  6694:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  6695:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  6696:     for(k=1; k <=(nlstate+ndeath); k++){
                   6697:       if (k != i) {
1.227     brouard  6698:        fprintf(ficgp,"#   current state %d\n",k);
                   6699:        for(j=1; j <=ncovmodel; j++){
                   6700:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   6701:          jk++; 
                   6702:        }
                   6703:        fprintf(ficgp,"\n");
1.126     brouard  6704:       }
                   6705:     }
1.223     brouard  6706:   }
1.187     brouard  6707:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  6708:   
1.145     brouard  6709:   /*goto avoid;*/
1.200     brouard  6710:   fprintf(ficgp,"\n##############\n#Graphics of probabilities or incidences\n#############\n");
1.187     brouard  6711:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   6712:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   6713:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   6714:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   6715:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6716:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6717:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6718:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6719:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   6720:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6721:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   6722:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   6723:   fprintf(ficgp,"#\n");
1.223     brouard  6724:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
                   6725:     fprintf(ficgp,"# ng=%d\n",ng);
1.225     brouard  6726:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);
1.223     brouard  6727:     for(jk=1; jk <=m; jk++) {
                   6728:       fprintf(ficgp,"#    jk=%d\n",jk);
                   6729:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng);
                   6730:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   6731:       if (ng==1){
                   6732:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   6733:        fprintf(ficgp,"\nunset log y");
                   6734:       }else if (ng==2){
                   6735:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   6736:        fprintf(ficgp,"\nset log y");
                   6737:       }else if (ng==3){
                   6738:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   6739:        fprintf(ficgp,"\nset log y");
                   6740:       }else
                   6741:        fprintf(ficgp,"\nunset title ");
                   6742:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   6743:       i=1;
                   6744:       for(k2=1; k2<=nlstate; k2++) {
                   6745:        k3=i;
                   6746:        for(k=1; k<=(nlstate+ndeath); k++) {
                   6747:          if (k != k2){
                   6748:            switch( ng) {
                   6749:            case 1:
                   6750:              if(nagesqr==0)
                   6751:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   6752:              else /* nagesqr =1 */
                   6753:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6754:              break;
                   6755:            case 2: /* ng=2 */
                   6756:              if(nagesqr==0)
                   6757:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   6758:              else /* nagesqr =1 */
                   6759:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6760:              break;
                   6761:            case 3:
                   6762:              if(nagesqr==0)
                   6763:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   6764:              else /* nagesqr =1 */
                   6765:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   6766:              break;
                   6767:            }
                   6768:            ij=1;/* To be checked else nbcode[0][0] wrong */
                   6769:            for(j=3; j <=ncovmodel-nagesqr; j++) {
                   6770:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
                   6771:              if(ij <=cptcovage) { /* Bug valgrind */
                   6772:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   6773:                  fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   6774:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6775:                  ij++;
                   6776:                }
                   6777:              }
                   6778:              else
1.227     brouard  6779:                fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]); /* Valgrind bug nbcode */
1.223     brouard  6780:            }
                   6781:          }else{
                   6782:            i=i-ncovmodel;
                   6783:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   6784:              fprintf(ficgp," (1.");
                   6785:          }
1.227     brouard  6786:          
1.223     brouard  6787:          if(ng != 1){
                   6788:            fprintf(ficgp,")/(1");
1.227     brouard  6789:            
1.223     brouard  6790:            for(k1=1; k1 <=nlstate; k1++){ 
                   6791:              if(nagesqr==0)
                   6792:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   6793:              else /* nagesqr =1 */
                   6794:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  6795:               
1.223     brouard  6796:              ij=1;
                   6797:              for(j=3; j <=ncovmodel-nagesqr; j++){
                   6798:                if(ij <=cptcovage) { /* Bug valgrind */
                   6799:                  if((j-2)==Tage[ij]) { /* Bug valgrind */
                   6800:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   6801:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6802:                    ij++;
                   6803:                  }
                   6804:                }
                   6805:                else
1.225     brouard  6806:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  6807:              }
                   6808:              fprintf(ficgp,")");
                   6809:            }
                   6810:            fprintf(ficgp,")");
                   6811:            if(ng ==2)
                   6812:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   6813:            else /* ng= 3 */
                   6814:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   6815:          }else{ /* end ng <> 1 */
                   6816:            if( k !=k2) /* logit p11 is hard to draw */
                   6817:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   6818:          }
                   6819:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   6820:            fprintf(ficgp,",");
                   6821:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   6822:            fprintf(ficgp,",");
                   6823:          i=i+ncovmodel;
                   6824:        } /* end k */
                   6825:       } /* end k2 */
                   6826:       fprintf(ficgp,"\n set out\n");
                   6827:     } /* end jk */
                   6828:   } /* end ng */
                   6829:   /* avoid: */
                   6830:   fflush(ficgp); 
1.126     brouard  6831: }  /* end gnuplot */
                   6832: 
                   6833: 
                   6834: /*************** Moving average **************/
1.219     brouard  6835: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  6836:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  6837:    
1.222     brouard  6838:    int i, cpt, cptcod;
                   6839:    int modcovmax =1;
                   6840:    int mobilavrange, mob;
                   6841:    int iage=0;
                   6842: 
                   6843:    double sum=0.;
                   6844:    double age;
                   6845:    double *sumnewp, *sumnewm;
                   6846:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   6847:   
                   6848:   
1.225     brouard  6849:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  6850:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   6851: 
                   6852:    sumnewp = vector(1,ncovcombmax);
                   6853:    sumnewm = vector(1,ncovcombmax);
                   6854:    agemingood = vector(1,ncovcombmax); 
                   6855:    agemaxgood = vector(1,ncovcombmax);
                   6856: 
                   6857:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6858:      sumnewm[cptcod]=0.;
                   6859:      sumnewp[cptcod]=0.;
                   6860:      agemingood[cptcod]=0;
                   6861:      agemaxgood[cptcod]=0;
                   6862:    }
                   6863:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   6864:   
                   6865:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   6866:      if(mobilav==1) mobilavrange=5; /* default */
                   6867:      else mobilavrange=mobilav;
                   6868:      for (age=bage; age<=fage; age++)
                   6869:        for (i=1; i<=nlstate;i++)
                   6870:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   6871:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   6872:      /* We keep the original values on the extreme ages bage, fage and for 
                   6873:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   6874:        we use a 5 terms etc. until the borders are no more concerned. 
                   6875:      */ 
                   6876:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   6877:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   6878:         for (i=1; i<=nlstate;i++){
                   6879:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6880:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   6881:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   6882:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   6883:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   6884:             }
                   6885:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   6886:           }
                   6887:         }
                   6888:        }/* end age */
                   6889:      }/* end mob */
                   6890:    }else
                   6891:      return -1;
                   6892:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6893:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   6894:      if(invalidvarcomb[cptcod]){
                   6895:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   6896:        continue;
                   6897:      }
1.219     brouard  6898: 
1.222     brouard  6899:      agemingood[cptcod]=fage-(mob-1)/2;
                   6900:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   6901:        sumnewm[cptcod]=0.;
                   6902:        for (i=1; i<=nlstate;i++){
                   6903:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6904:        }
                   6905:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   6906:         agemingood[cptcod]=age;
                   6907:        }else{ /* bad */
                   6908:         for (i=1; i<=nlstate;i++){
                   6909:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6910:         } /* i */
                   6911:        } /* end bad */
                   6912:      }/* age */
                   6913:      sum=0.;
                   6914:      for (i=1; i<=nlstate;i++){
                   6915:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6916:      }
                   6917:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   6918:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   6919:        /* for (i=1; i<=nlstate;i++){ */
                   6920:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   6921:        /* } /\* i *\/ */
                   6922:      } /* end bad */
                   6923:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   6924:      /* From youngest, finding the oldest wrong */
                   6925:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   6926:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   6927:        sumnewm[cptcod]=0.;
                   6928:        for (i=1; i<=nlstate;i++){
                   6929:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6930:        }
                   6931:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   6932:         agemaxgood[cptcod]=age;
                   6933:        }else{ /* bad */
                   6934:         for (i=1; i<=nlstate;i++){
                   6935:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6936:         } /* i */
                   6937:        } /* end bad */
                   6938:      }/* age */
                   6939:      sum=0.;
                   6940:      for (i=1; i<=nlstate;i++){
                   6941:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6942:      }
                   6943:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   6944:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   6945:        /* for (i=1; i<=nlstate;i++){ */
                   6946:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   6947:        /* } /\* i *\/ */
                   6948:      } /* end bad */
                   6949:                
                   6950:      for (age=bage; age<=fage; age++){
1.235   ! brouard  6951:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  6952:        sumnewp[cptcod]=0.;
                   6953:        sumnewm[cptcod]=0.;
                   6954:        for (i=1; i<=nlstate;i++){
                   6955:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   6956:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   6957:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   6958:        }
                   6959:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   6960:      }
                   6961:      /* printf("\n"); */
                   6962:      /* } */
                   6963:      /* brutal averaging */
                   6964:      for (i=1; i<=nlstate;i++){
                   6965:        for (age=1; age<=bage; age++){
                   6966:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   6967:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   6968:        }       
                   6969:        for (age=fage; age<=AGESUP; age++){
                   6970:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   6971:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   6972:        }
                   6973:      } /* end i status */
                   6974:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   6975:        for (age=1; age<=AGESUP; age++){
                   6976:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   6977:         mobaverage[(int)age][i][cptcod]=0.;
                   6978:        }
                   6979:      }
                   6980:    }/* end cptcod */
                   6981:    free_vector(sumnewm,1, ncovcombmax);
                   6982:    free_vector(sumnewp,1, ncovcombmax);
                   6983:    free_vector(agemaxgood,1, ncovcombmax);
                   6984:    free_vector(agemingood,1, ncovcombmax);
                   6985:    return 0;
                   6986:  }/* End movingaverage */
1.218     brouard  6987:  
1.126     brouard  6988: 
                   6989: /************** Forecasting ******************/
1.235   ! brouard  6990:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  6991:   /* proj1, year, month, day of starting projection 
                   6992:      agemin, agemax range of age
                   6993:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   6994:      anproj2 year of en of projection (same day and month as proj1).
                   6995:   */
1.235   ! brouard  6996:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  6997:   double agec; /* generic age */
                   6998:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   6999:   double *popeffectif,*popcount;
                   7000:   double ***p3mat;
1.218     brouard  7001:   /* double ***mobaverage; */
1.126     brouard  7002:   char fileresf[FILENAMELENGTH];
                   7003: 
                   7004:   agelim=AGESUP;
1.211     brouard  7005:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7006:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7007:      We still use firstpass and lastpass as another selection.
                   7008:   */
1.214     brouard  7009:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7010:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7011:  
1.201     brouard  7012:   strcpy(fileresf,"F_"); 
                   7013:   strcat(fileresf,fileresu);
1.126     brouard  7014:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7015:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7016:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7017:   }
1.235   ! brouard  7018:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
        !          7019:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7020: 
1.225     brouard  7021:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7022: 
                   7023: 
                   7024:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7025:   if (stepm<=12) stepsize=1;
                   7026:   if(estepm < stepm){
                   7027:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7028:   }
                   7029:   else  hstepm=estepm;   
                   7030: 
                   7031:   hstepm=hstepm/stepm; 
                   7032:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7033:                                fractional in yp1 */
                   7034:   anprojmean=yp;
                   7035:   yp2=modf((yp1*12),&yp);
                   7036:   mprojmean=yp;
                   7037:   yp1=modf((yp2*30.5),&yp);
                   7038:   jprojmean=yp;
                   7039:   if(jprojmean==0) jprojmean=1;
                   7040:   if(mprojmean==0) jprojmean=1;
                   7041: 
1.227     brouard  7042:   i1=pow(2,cptcoveff);
1.126     brouard  7043:   if (cptcovn < 1){i1=1;}
                   7044:   
                   7045:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7046:   
                   7047:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7048:   
1.126     brouard  7049: /*           if (h==(int)(YEARM*yearp)){ */
1.235   ! brouard  7050:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          7051:   for(k=1; k<=i1;k++){
        !          7052:     if(TKresult[nres]!= k)
        !          7053:       continue;
1.227     brouard  7054:     if(invalidvarcomb[k]){
                   7055:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7056:       continue;
                   7057:     }
                   7058:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7059:     for(j=1;j<=cptcoveff;j++) {
                   7060:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7061:     }
1.235   ! brouard  7062:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          7063:       printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          7064:       fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          7065:     }
1.227     brouard  7066:     fprintf(ficresf," yearproj age");
                   7067:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7068:       for(i=1; i<=nlstate;i++)               
                   7069:        fprintf(ficresf," p%d%d",i,j);
                   7070:       fprintf(ficresf," wp.%d",j);
                   7071:     }
                   7072:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7073:       fprintf(ficresf,"\n");
                   7074:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7075:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7076:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7077:        nhstepm = nhstepm/hstepm; 
                   7078:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7079:        oldm=oldms;savm=savms;
1.235   ! brouard  7080:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7081:        
                   7082:        for (h=0; h<=nhstepm; h++){
                   7083:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7084:            fprintf(ficresf,"\n");
                   7085:            for(j=1;j<=cptcoveff;j++) 
                   7086:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7087:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7088:          } 
                   7089:          for(j=1; j<=nlstate+ndeath;j++) {
                   7090:            ppij=0.;
                   7091:            for(i=1; i<=nlstate;i++) {
                   7092:              if (mobilav==1) 
                   7093:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7094:              else {
                   7095:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7096:              }
                   7097:              if (h*hstepm/YEARM*stepm== yearp) {
                   7098:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7099:              }
                   7100:            } /* end i */
                   7101:            if (h*hstepm/YEARM*stepm==yearp) {
                   7102:              fprintf(ficresf," %.3f", ppij);
                   7103:            }
                   7104:          }/* end j */
                   7105:        } /* end h */
                   7106:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7107:       } /* end agec */
                   7108:     } /* end yearp */
                   7109:   } /* end  k */
1.219     brouard  7110:        
1.126     brouard  7111:   fclose(ficresf);
1.215     brouard  7112:   printf("End of Computing forecasting \n");
                   7113:   fprintf(ficlog,"End of Computing forecasting\n");
                   7114: 
1.126     brouard  7115: }
                   7116: 
1.218     brouard  7117: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7118: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7119: /*   /\* back1, year, month, day of starting backection  */
                   7120: /*      agemin, agemax range of age */
                   7121: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7122: /*      anback2 year of en of backection (same day and month as back1). */
                   7123: /*   *\/ */
                   7124: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7125: /*   double agec; /\* generic age *\/ */
                   7126: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7127: /*   double *popeffectif,*popcount; */
                   7128: /*   double ***p3mat; */
                   7129: /*   /\* double ***mobaverage; *\/ */
                   7130: /*   char fileresfb[FILENAMELENGTH]; */
                   7131:        
                   7132: /*   agelim=AGESUP; */
                   7133: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7134: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7135: /*      We still use firstpass and lastpass as another selection. */
                   7136: /*   *\/ */
                   7137: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7138: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7139: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7140:        
                   7141: /*   strcpy(fileresfb,"FB_");  */
                   7142: /*   strcat(fileresfb,fileresu); */
                   7143: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7144: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7145: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7146: /*   } */
                   7147: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7148: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7149:        
1.225     brouard  7150: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7151:        
                   7152: /*   /\* if (mobilav!=0) { *\/ */
                   7153: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7154: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7155: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7156: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7157: /*   /\*   } *\/ */
                   7158: /*   /\* } *\/ */
                   7159:        
                   7160: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7161: /*   if (stepm<=12) stepsize=1; */
                   7162: /*   if(estepm < stepm){ */
                   7163: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7164: /*   } */
                   7165: /*   else  hstepm=estepm;    */
                   7166:        
                   7167: /*   hstepm=hstepm/stepm;  */
                   7168: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7169: /*                                fractional in yp1 *\/ */
                   7170: /*   anprojmean=yp; */
                   7171: /*   yp2=modf((yp1*12),&yp); */
                   7172: /*   mprojmean=yp; */
                   7173: /*   yp1=modf((yp2*30.5),&yp); */
                   7174: /*   jprojmean=yp; */
                   7175: /*   if(jprojmean==0) jprojmean=1; */
                   7176: /*   if(mprojmean==0) jprojmean=1; */
                   7177:        
1.225     brouard  7178: /*   i1=cptcoveff; */
1.218     brouard  7179: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7180:   
1.218     brouard  7181: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7182:   
1.218     brouard  7183: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7184:        
                   7185: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7186: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7187: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7188: /*       k=k+1; */
                   7189: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7190: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7191: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7192: /*       } */
                   7193: /*       fprintf(ficresfb," yearbproj age"); */
                   7194: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7195: /*                             for(i=1; i<=nlstate;i++)               */
                   7196: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7197: /*                             fprintf(ficresfb," p.%d",j); */
                   7198: /*       } */
                   7199: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7200: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7201: /*                             fprintf(ficresfb,"\n"); */
                   7202: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7203: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7204: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7205: /*                                     nhstepm = nhstepm/hstepm;  */
                   7206: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7207: /*                                     oldm=oldms;savm=savms; */
                   7208: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7209: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7210: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7211: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7212: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7213: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7214: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7215: /*                                             }  */
                   7216: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7217: /*                                                     ppij=0.; */
                   7218: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7219: /*                                                             if (mobilav==1)  */
                   7220: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7221: /*                                                             else { */
                   7222: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7223: /*                                                             } */
                   7224: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7225: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7226: /*                                                             } */
                   7227: /*                                                     } /\* end i *\/ */
                   7228: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7229: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7230: /*                                                     } */
                   7231: /*                                             }/\* end j *\/ */
                   7232: /*                                     } /\* end h *\/ */
                   7233: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7234: /*                             } /\* end agec *\/ */
                   7235: /*       } /\* end yearp *\/ */
                   7236: /*     } /\* end cptcod *\/ */
                   7237: /*   } /\* end  cptcov *\/ */
                   7238:        
                   7239: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7240:        
                   7241: /*   fclose(ficresfb); */
                   7242: /*   printf("End of Computing Back forecasting \n"); */
                   7243: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7244:        
1.218     brouard  7245: /* } */
1.217     brouard  7246: 
1.126     brouard  7247: /************** Forecasting *****not tested NB*************/
1.227     brouard  7248: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7249:   
1.227     brouard  7250: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7251: /*   int *popage; */
                   7252: /*   double calagedatem, agelim, kk1, kk2; */
                   7253: /*   double *popeffectif,*popcount; */
                   7254: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7255: /*   /\* double ***mobaverage; *\/ */
                   7256: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7257: 
1.227     brouard  7258: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7259: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7260: /*   agelim=AGESUP; */
                   7261: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7262:   
1.227     brouard  7263: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7264:   
                   7265:   
1.227     brouard  7266: /*   strcpy(filerespop,"POP_");  */
                   7267: /*   strcat(filerespop,fileresu); */
                   7268: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7269: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7270: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7271: /*   } */
                   7272: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7273: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7274: 
1.227     brouard  7275: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7276: 
1.227     brouard  7277: /*   /\* if (mobilav!=0) { *\/ */
                   7278: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7279: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7280: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7281: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7282: /*   /\*   } *\/ */
                   7283: /*   /\* } *\/ */
1.126     brouard  7284: 
1.227     brouard  7285: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7286: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7287:   
1.227     brouard  7288: /*   agelim=AGESUP; */
1.126     brouard  7289:   
1.227     brouard  7290: /*   hstepm=1; */
                   7291: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7292:        
1.227     brouard  7293: /*   if (popforecast==1) { */
                   7294: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7295: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7296: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7297: /*     }  */
                   7298: /*     popage=ivector(0,AGESUP); */
                   7299: /*     popeffectif=vector(0,AGESUP); */
                   7300: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7301:     
1.227     brouard  7302: /*     i=1;    */
                   7303: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7304:     
1.227     brouard  7305: /*     imx=i; */
                   7306: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7307: /*   } */
1.218     brouard  7308:   
1.227     brouard  7309: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7310: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7311: /*       k=k+1; */
                   7312: /*       fprintf(ficrespop,"\n#******"); */
                   7313: /*       for(j=1;j<=cptcoveff;j++) { */
                   7314: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7315: /*       } */
                   7316: /*       fprintf(ficrespop,"******\n"); */
                   7317: /*       fprintf(ficrespop,"# Age"); */
                   7318: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7319: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7320:       
1.227     brouard  7321: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7322: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7323:        
1.227     brouard  7324: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7325: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7326: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7327:          
1.227     brouard  7328: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7329: /*       oldm=oldms;savm=savms; */
                   7330: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7331:          
1.227     brouard  7332: /*       for (h=0; h<=nhstepm; h++){ */
                   7333: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7334: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7335: /*         }  */
                   7336: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7337: /*           kk1=0.;kk2=0; */
                   7338: /*           for(i=1; i<=nlstate;i++) {               */
                   7339: /*             if (mobilav==1)  */
                   7340: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7341: /*             else { */
                   7342: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7343: /*             } */
                   7344: /*           } */
                   7345: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7346: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7347: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7348: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7349: /*           } */
                   7350: /*         } */
                   7351: /*         for(i=1; i<=nlstate;i++){ */
                   7352: /*           kk1=0.; */
                   7353: /*           for(j=1; j<=nlstate;j++){ */
                   7354: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7355: /*           } */
                   7356: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7357: /*         } */
1.218     brouard  7358:            
1.227     brouard  7359: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7360: /*           for(j=1; j<=nlstate;j++)  */
                   7361: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7362: /*       } */
                   7363: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7364: /*     } */
                   7365: /*       } */
1.218     brouard  7366:       
1.227     brouard  7367: /*       /\******\/ */
1.218     brouard  7368:       
1.227     brouard  7369: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7370: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7371: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7372: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7373: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7374:          
1.227     brouard  7375: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7376: /*       oldm=oldms;savm=savms; */
                   7377: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7378: /*       for (h=0; h<=nhstepm; h++){ */
                   7379: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7380: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7381: /*         }  */
                   7382: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7383: /*           kk1=0.;kk2=0; */
                   7384: /*           for(i=1; i<=nlstate;i++) {               */
                   7385: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7386: /*           } */
                   7387: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7388: /*         } */
                   7389: /*       } */
                   7390: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7391: /*     } */
                   7392: /*       } */
                   7393: /*     }  */
                   7394: /*   } */
1.218     brouard  7395:   
1.227     brouard  7396: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7397:   
1.227     brouard  7398: /*   if (popforecast==1) { */
                   7399: /*     free_ivector(popage,0,AGESUP); */
                   7400: /*     free_vector(popeffectif,0,AGESUP); */
                   7401: /*     free_vector(popcount,0,AGESUP); */
                   7402: /*   } */
                   7403: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7404: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7405: /*   fclose(ficrespop); */
                   7406: /* } /\* End of popforecast *\/ */
1.218     brouard  7407:  
1.126     brouard  7408: int fileappend(FILE *fichier, char *optionfich)
                   7409: {
                   7410:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7411:     printf("Problem with file: %s\n", optionfich);
                   7412:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7413:     return (0);
                   7414:   }
                   7415:   fflush(fichier);
                   7416:   return (1);
                   7417: }
                   7418: 
                   7419: 
                   7420: /**************** function prwizard **********************/
                   7421: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7422: {
                   7423: 
                   7424:   /* Wizard to print covariance matrix template */
                   7425: 
1.164     brouard  7426:   char ca[32], cb[32];
                   7427:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7428:   int numlinepar;
                   7429: 
                   7430:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7431:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7432:   for(i=1; i <=nlstate; i++){
                   7433:     jj=0;
                   7434:     for(j=1; j <=nlstate+ndeath; j++){
                   7435:       if(j==i) continue;
                   7436:       jj++;
                   7437:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7438:       printf("%1d%1d",i,j);
                   7439:       fprintf(ficparo,"%1d%1d",i,j);
                   7440:       for(k=1; k<=ncovmodel;k++){
                   7441:        /*        printf(" %lf",param[i][j][k]); */
                   7442:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7443:        printf(" 0.");
                   7444:        fprintf(ficparo," 0.");
                   7445:       }
                   7446:       printf("\n");
                   7447:       fprintf(ficparo,"\n");
                   7448:     }
                   7449:   }
                   7450:   printf("# Scales (for hessian or gradient estimation)\n");
                   7451:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7452:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7453:   for(i=1; i <=nlstate; i++){
                   7454:     jj=0;
                   7455:     for(j=1; j <=nlstate+ndeath; j++){
                   7456:       if(j==i) continue;
                   7457:       jj++;
                   7458:       fprintf(ficparo,"%1d%1d",i,j);
                   7459:       printf("%1d%1d",i,j);
                   7460:       fflush(stdout);
                   7461:       for(k=1; k<=ncovmodel;k++){
                   7462:        /*      printf(" %le",delti3[i][j][k]); */
                   7463:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7464:        printf(" 0.");
                   7465:        fprintf(ficparo," 0.");
                   7466:       }
                   7467:       numlinepar++;
                   7468:       printf("\n");
                   7469:       fprintf(ficparo,"\n");
                   7470:     }
                   7471:   }
                   7472:   printf("# Covariance matrix\n");
                   7473: /* # 121 Var(a12)\n\ */
                   7474: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7475: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7476: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7477: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7478: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7479: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7480: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7481:   fflush(stdout);
                   7482:   fprintf(ficparo,"# Covariance matrix\n");
                   7483:   /* # 121 Var(a12)\n\ */
                   7484:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7485:   /* #   ...\n\ */
                   7486:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7487:   
                   7488:   for(itimes=1;itimes<=2;itimes++){
                   7489:     jj=0;
                   7490:     for(i=1; i <=nlstate; i++){
                   7491:       for(j=1; j <=nlstate+ndeath; j++){
                   7492:        if(j==i) continue;
                   7493:        for(k=1; k<=ncovmodel;k++){
                   7494:          jj++;
                   7495:          ca[0]= k+'a'-1;ca[1]='\0';
                   7496:          if(itimes==1){
                   7497:            printf("#%1d%1d%d",i,j,k);
                   7498:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7499:          }else{
                   7500:            printf("%1d%1d%d",i,j,k);
                   7501:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7502:            /*  printf(" %.5le",matcov[i][j]); */
                   7503:          }
                   7504:          ll=0;
                   7505:          for(li=1;li <=nlstate; li++){
                   7506:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7507:              if(lj==li) continue;
                   7508:              for(lk=1;lk<=ncovmodel;lk++){
                   7509:                ll++;
                   7510:                if(ll<=jj){
                   7511:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7512:                  if(ll<jj){
                   7513:                    if(itimes==1){
                   7514:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7515:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7516:                    }else{
                   7517:                      printf(" 0.");
                   7518:                      fprintf(ficparo," 0.");
                   7519:                    }
                   7520:                  }else{
                   7521:                    if(itimes==1){
                   7522:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7523:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7524:                    }else{
                   7525:                      printf(" 0.");
                   7526:                      fprintf(ficparo," 0.");
                   7527:                    }
                   7528:                  }
                   7529:                }
                   7530:              } /* end lk */
                   7531:            } /* end lj */
                   7532:          } /* end li */
                   7533:          printf("\n");
                   7534:          fprintf(ficparo,"\n");
                   7535:          numlinepar++;
                   7536:        } /* end k*/
                   7537:       } /*end j */
                   7538:     } /* end i */
                   7539:   } /* end itimes */
                   7540: 
                   7541: } /* end of prwizard */
                   7542: /******************* Gompertz Likelihood ******************************/
                   7543: double gompertz(double x[])
                   7544: { 
                   7545:   double A,B,L=0.0,sump=0.,num=0.;
                   7546:   int i,n=0; /* n is the size of the sample */
                   7547: 
1.220     brouard  7548:   for (i=1;i<=imx ; i++) {
1.126     brouard  7549:     sump=sump+weight[i];
                   7550:     /*    sump=sump+1;*/
                   7551:     num=num+1;
                   7552:   }
                   7553:  
                   7554:  
                   7555:   /* for (i=0; i<=imx; i++) 
                   7556:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7557: 
                   7558:   for (i=1;i<=imx ; i++)
                   7559:     {
                   7560:       if (cens[i] == 1 && wav[i]>1)
                   7561:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   7562:       
                   7563:       if (cens[i] == 0 && wav[i]>1)
                   7564:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   7565:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   7566:       
                   7567:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7568:       if (wav[i] > 1 ) { /* ??? */
                   7569:        L=L+A*weight[i];
                   7570:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7571:       }
                   7572:     }
                   7573: 
                   7574:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7575:  
                   7576:   return -2*L*num/sump;
                   7577: }
                   7578: 
1.136     brouard  7579: #ifdef GSL
                   7580: /******************* Gompertz_f Likelihood ******************************/
                   7581: double gompertz_f(const gsl_vector *v, void *params)
                   7582: { 
                   7583:   double A,B,LL=0.0,sump=0.,num=0.;
                   7584:   double *x= (double *) v->data;
                   7585:   int i,n=0; /* n is the size of the sample */
                   7586: 
                   7587:   for (i=0;i<=imx-1 ; i++) {
                   7588:     sump=sump+weight[i];
                   7589:     /*    sump=sump+1;*/
                   7590:     num=num+1;
                   7591:   }
                   7592:  
                   7593:  
                   7594:   /* for (i=0; i<=imx; i++) 
                   7595:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7596:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   7597:   for (i=1;i<=imx ; i++)
                   7598:     {
                   7599:       if (cens[i] == 1 && wav[i]>1)
                   7600:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   7601:       
                   7602:       if (cens[i] == 0 && wav[i]>1)
                   7603:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   7604:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   7605:       
                   7606:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7607:       if (wav[i] > 1 ) { /* ??? */
                   7608:        LL=LL+A*weight[i];
                   7609:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7610:       }
                   7611:     }
                   7612: 
                   7613:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7614:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   7615:  
                   7616:   return -2*LL*num/sump;
                   7617: }
                   7618: #endif
                   7619: 
1.126     brouard  7620: /******************* Printing html file ***********/
1.201     brouard  7621: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7622:                  int lastpass, int stepm, int weightopt, char model[],\
                   7623:                  int imx,  double p[],double **matcov,double agemortsup){
                   7624:   int i,k;
                   7625: 
                   7626:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   7627:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   7628:   for (i=1;i<=2;i++) 
                   7629:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  7630:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  7631:   fprintf(fichtm,"</ul>");
                   7632: 
                   7633: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   7634: 
                   7635:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   7636: 
                   7637:  for (k=agegomp;k<(agemortsup-2);k++) 
                   7638:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   7639: 
                   7640:  
                   7641:   fflush(fichtm);
                   7642: }
                   7643: 
                   7644: /******************* Gnuplot file **************/
1.201     brouard  7645: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  7646: 
                   7647:   char dirfileres[132],optfileres[132];
1.164     brouard  7648: 
1.126     brouard  7649:   int ng;
                   7650: 
                   7651: 
                   7652:   /*#ifdef windows */
                   7653:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   7654:     /*#endif */
                   7655: 
                   7656: 
                   7657:   strcpy(dirfileres,optionfilefiname);
                   7658:   strcpy(optfileres,"vpl");
1.199     brouard  7659:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  7660:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  7661:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  7662:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  7663:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   7664: 
                   7665: } 
                   7666: 
1.136     brouard  7667: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   7668: {
1.126     brouard  7669: 
1.136     brouard  7670:   /*-------- data file ----------*/
                   7671:   FILE *fic;
                   7672:   char dummy[]="                         ";
1.223     brouard  7673:   int i=0, j=0, n=0, iv=0;
                   7674:   int lstra;
1.136     brouard  7675:   int linei, month, year,iout;
                   7676:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  7677:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  7678:   char *stratrunc;
1.223     brouard  7679: 
1.126     brouard  7680: 
                   7681: 
1.136     brouard  7682:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  7683:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   7684:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  7685:   }
1.126     brouard  7686: 
1.136     brouard  7687:   i=1;
                   7688:   linei=0;
                   7689:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   7690:     linei=linei+1;
                   7691:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   7692:       if(line[j] == '\t')
                   7693:        line[j] = ' ';
                   7694:     }
                   7695:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   7696:       ;
                   7697:     };
                   7698:     line[j+1]=0;  /* Trims blanks at end of line */
                   7699:     if(line[0]=='#'){
                   7700:       fprintf(ficlog,"Comment line\n%s\n",line);
                   7701:       printf("Comment line\n%s\n",line);
                   7702:       continue;
                   7703:     }
                   7704:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  7705:     strcpy(line, linetmp);
1.223     brouard  7706:     
                   7707:     /* Loops on waves */
                   7708:     for (j=maxwav;j>=1;j--){
                   7709:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.232     brouard  7710:                                cutv(stra, strb, line, ' '); 
                   7711:                                if(strb[0]=='.') { /* Missing value */
                   7712:                                        lval=-1;
                   7713:                                        cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   7714:                                        cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   7715:                                        if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   7716:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   7717:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   7718:                                                return 1;
                   7719:                                        }
                   7720:                                }else{
                   7721:                                        errno=0;
                   7722:                                        /* what_kind_of_number(strb); */
                   7723:                                        dval=strtod(strb,&endptr); 
                   7724:                                        /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   7725:                                        /* if(strb != endptr && *endptr == '\0') */
                   7726:                                        /*    dval=dlval; */
                   7727:                                        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7728:                                        if( strb[0]=='\0' || (*endptr != '\0')){
                   7729:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   7730:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   7731:                                                return 1;
                   7732:                                        }
                   7733:                                        cotqvar[j][iv][i]=dval; 
                   7734:                                        cotvar[j][ntv+iv][i]=dval; 
                   7735:                                }
                   7736:                                strcpy(line,stra);
1.223     brouard  7737:       }/* end loop ntqv */
1.225     brouard  7738:       
1.223     brouard  7739:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.232     brouard  7740:                                cutv(stra, strb, line, ' '); 
                   7741:                                if(strb[0]=='.') { /* Missing value */
                   7742:                                        lval=-1;
                   7743:                                }else{
                   7744:                                        errno=0;
                   7745:                                        lval=strtol(strb,&endptr,10); 
                   7746:                                        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7747:                                        if( strb[0]=='\0' || (*endptr != '\0')){
                   7748:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   7749:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   7750:                                                return 1;
                   7751:                                        }
                   7752:                                }
                   7753:                                if(lval <-1 || lval >1){
                   7754:                                        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  7755:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7756:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.232     brouard  7757:  For example, for multinomial values like 1, 2 and 3,\n                                                                        \
                   7758:  build V1=0 V2=0 for the reference value (1),\n                                                                                                        \
                   7759:         V1=1 V2=0 for (2) \n                                                                                                                                                                           \
1.223     brouard  7760:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.232     brouard  7761:  output of IMaCh is often meaningless.\n                                                                                                                               \
1.223     brouard  7762:  Exiting.\n",lval,linei, i,line,j);
1.232     brouard  7763:                                        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  7764:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7765:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.232     brouard  7766:  For example, for multinomial values like 1, 2 and 3,\n                                                                        \
                   7767:  build V1=0 V2=0 for the reference value (1),\n                                                                                                        \
                   7768:         V1=1 V2=0 for (2) \n                                                                                                                                                                           \
1.223     brouard  7769:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.232     brouard  7770:  output of IMaCh is often meaningless.\n                                                                                                                               \
1.223     brouard  7771:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.232     brouard  7772:                                        return 1;
                   7773:                                }
                   7774:                                cotvar[j][iv][i]=(double)(lval);
                   7775:                                strcpy(line,stra);
1.223     brouard  7776:       }/* end loop ntv */
1.225     brouard  7777:       
1.223     brouard  7778:       /* Statuses  at wave */
1.137     brouard  7779:       cutv(stra, strb, line, ' '); 
1.223     brouard  7780:       if(strb[0]=='.') { /* Missing value */
1.232     brouard  7781:                                lval=-1;
1.136     brouard  7782:       }else{
1.232     brouard  7783:                                errno=0;
                   7784:                                lval=strtol(strb,&endptr,10); 
                   7785:                                /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7786:                                if( strb[0]=='\0' || (*endptr != '\0')){
                   7787:                                        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   7788:                                        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   7789:                                        return 1;
                   7790:                                }
1.136     brouard  7791:       }
1.225     brouard  7792:       
1.136     brouard  7793:       s[j][i]=lval;
1.225     brouard  7794:       
1.223     brouard  7795:       /* Date of Interview */
1.136     brouard  7796:       strcpy(line,stra);
                   7797:       cutv(stra, strb,line,' ');
1.169     brouard  7798:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7799:       }
1.169     brouard  7800:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  7801:        month=99;
                   7802:        year=9999;
1.136     brouard  7803:       }else{
1.225     brouard  7804:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   7805:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   7806:        return 1;
1.136     brouard  7807:       }
                   7808:       anint[j][i]= (double) year; 
                   7809:       mint[j][i]= (double)month; 
                   7810:       strcpy(line,stra);
1.223     brouard  7811:     } /* End loop on waves */
1.225     brouard  7812:     
1.223     brouard  7813:     /* Date of death */
1.136     brouard  7814:     cutv(stra, strb,line,' '); 
1.169     brouard  7815:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7816:     }
1.169     brouard  7817:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  7818:       month=99;
                   7819:       year=9999;
                   7820:     }else{
1.141     brouard  7821:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  7822:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   7823:       return 1;
1.136     brouard  7824:     }
                   7825:     andc[i]=(double) year; 
                   7826:     moisdc[i]=(double) month; 
                   7827:     strcpy(line,stra);
                   7828:     
1.223     brouard  7829:     /* Date of birth */
1.136     brouard  7830:     cutv(stra, strb,line,' '); 
1.169     brouard  7831:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7832:     }
1.169     brouard  7833:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  7834:       month=99;
                   7835:       year=9999;
                   7836:     }else{
1.141     brouard  7837:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   7838:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  7839:       return 1;
1.136     brouard  7840:     }
                   7841:     if (year==9999) {
1.141     brouard  7842:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   7843:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  7844:       return 1;
                   7845:       
1.136     brouard  7846:     }
                   7847:     annais[i]=(double)(year);
                   7848:     moisnais[i]=(double)(month); 
                   7849:     strcpy(line,stra);
1.225     brouard  7850:     
1.223     brouard  7851:     /* Sample weight */
1.136     brouard  7852:     cutv(stra, strb,line,' '); 
                   7853:     errno=0;
                   7854:     dval=strtod(strb,&endptr); 
                   7855:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  7856:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   7857:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  7858:       fflush(ficlog);
                   7859:       return 1;
                   7860:     }
                   7861:     weight[i]=dval; 
                   7862:     strcpy(line,stra);
1.225     brouard  7863:     
1.223     brouard  7864:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   7865:       cutv(stra, strb, line, ' '); 
                   7866:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  7867:        lval=-1;
1.223     brouard  7868:       }else{
1.225     brouard  7869:        errno=0;
                   7870:        /* what_kind_of_number(strb); */
                   7871:        dval=strtod(strb,&endptr);
                   7872:        /* if(strb != endptr && *endptr == '\0') */
                   7873:        /*   dval=dlval; */
                   7874:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7875:        if( strb[0]=='\0' || (*endptr != '\0')){
                   7876:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   7877:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   7878:          return 1;
                   7879:        }
                   7880:        coqvar[iv][i]=dval; 
1.226     brouard  7881:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  7882:       }
                   7883:       strcpy(line,stra);
                   7884:     }/* end loop nqv */
1.136     brouard  7885:     
1.223     brouard  7886:     /* Covariate values */
1.136     brouard  7887:     for (j=ncovcol;j>=1;j--){
                   7888:       cutv(stra, strb,line,' '); 
1.223     brouard  7889:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  7890:        lval=-1;
1.136     brouard  7891:       }else{
1.225     brouard  7892:        errno=0;
                   7893:        lval=strtol(strb,&endptr,10); 
                   7894:        if( strb[0]=='\0' || (*endptr != '\0')){
                   7895:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   7896:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   7897:          return 1;
                   7898:        }
1.136     brouard  7899:       }
                   7900:       if(lval <-1 || lval >1){
1.225     brouard  7901:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  7902:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7903:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  7904:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   7905:  build V1=0 V2=0 for the reference value (1),\n                                \
                   7906:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  7907:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  7908:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  7909:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  7910:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  7911:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7912:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  7913:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   7914:  build V1=0 V2=0 for the reference value (1),\n                                \
                   7915:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  7916:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  7917:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  7918:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  7919:        return 1;
1.136     brouard  7920:       }
                   7921:       covar[j][i]=(double)(lval);
                   7922:       strcpy(line,stra);
                   7923:     }  
                   7924:     lstra=strlen(stra);
1.225     brouard  7925:     
1.136     brouard  7926:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   7927:       stratrunc = &(stra[lstra-9]);
                   7928:       num[i]=atol(stratrunc);
                   7929:     }
                   7930:     else
                   7931:       num[i]=atol(stra);
                   7932:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   7933:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   7934:     
                   7935:     i=i+1;
                   7936:   } /* End loop reading  data */
1.225     brouard  7937:   
1.136     brouard  7938:   *imax=i-1; /* Number of individuals */
                   7939:   fclose(fic);
1.225     brouard  7940:   
1.136     brouard  7941:   return (0);
1.164     brouard  7942:   /* endread: */
1.225     brouard  7943:   printf("Exiting readdata: ");
                   7944:   fclose(fic);
                   7945:   return (1);
1.223     brouard  7946: }
1.126     brouard  7947: 
1.234     brouard  7948: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  7949:   char *p1 = *stri, *p2 = *stri;
1.235   ! brouard  7950:   while (*p2 == ' ')
1.234     brouard  7951:     p2++; 
                   7952:   /* while ((*p1++ = *p2++) !=0) */
                   7953:   /*   ; */
                   7954:   /* do */
                   7955:   /*   while (*p2 == ' ') */
                   7956:   /*     p2++; */
                   7957:   /* while (*p1++ == *p2++); */
                   7958:   *stri=p2; 
1.145     brouard  7959: }
                   7960: 
1.235   ! brouard  7961: int decoderesult ( char resultline[], int nres)
1.230     brouard  7962: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   7963: {
1.235   ! brouard  7964:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  7965:   char resultsav[MAXLINE];
1.234     brouard  7966:   int resultmodel[MAXLINE];
                   7967:   int modelresult[MAXLINE];
1.230     brouard  7968:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   7969: 
1.234     brouard  7970:   removefirstspace(&resultline);
1.233     brouard  7971:   printf("decoderesult:%s\n",resultline);
1.230     brouard  7972: 
                   7973:   if (strstr(resultline,"v") !=0){
                   7974:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   7975:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   7976:     return 1;
                   7977:   }
                   7978:   trimbb(resultsav, resultline);
                   7979:   if (strlen(resultsav) >1){
                   7980:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   7981:   }
1.234     brouard  7982:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   7983:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   7984:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   7985:   }
                   7986:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   7987:     if(nbocc(resultsav,'=') >1){
                   7988:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   7989:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   7990:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   7991:     }else
                   7992:       cutl(strc,strd,resultsav,'=');
1.230     brouard  7993:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  7994:     
1.230     brouard  7995:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   7996:     Tvarsel[k]=atoi(strc);
                   7997:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   7998:     /* cptcovsel++;     */
                   7999:     if (nbocc(stra,'=') >0)
                   8000:       strcpy(resultsav,stra); /* and analyzes it */
                   8001:   }
1.235   ! brouard  8002:   /* Checking for missing or useless values in comparison of current model needs */
1.234     brouard  8003:   for(k1=1; k1<= cptcovt ;k1++){ /* model line */
                   8004:     if(Typevar[k1]==0){
                   8005:       match=0;
                   8006:       for(k2=1; k2 <=j;k2++){
                   8007:        if(Tvar[k1]==Tvarsel[k2]) {
                   8008:          modelresult[k2]=k1;
                   8009:          match=1;
                   8010:          break;
                   8011:        }
                   8012:       }
                   8013:       if(match == 0){
                   8014:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8015:       }
                   8016:     }
                   8017:   }
1.235   ! brouard  8018:   /* Checking for missing or useless values in comparison of current model needs */
        !          8019:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8020:     match=0;
1.235   ! brouard  8021:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          8022:       if(Typevar[k1]==0){ /* Single */
        !          8023:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=5 == Tvarsel[1]=4   */
        !          8024:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8025:          ++match;
                   8026:        }
                   8027:       }
                   8028:     }
                   8029:     if(match == 0){
                   8030:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8031:     }else if(match > 1){
                   8032:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8033:     }
                   8034:   }
1.235   ! brouard  8035:       
1.234     brouard  8036:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235   ! brouard  8037:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
        !          8038:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
        !          8039:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
        !          8040:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
        !          8041:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
        !          8042:   /*    1 0 0 0 */
        !          8043:   /*    2 1 0 0 */
        !          8044:   /*    3 0 1 0 */ 
        !          8045:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
        !          8046:   /*    5 0 0 1 */
        !          8047:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
        !          8048:   /*    7 0 1 1 */
        !          8049:   /*    8 1 1 1 */
        !          8050:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
        !          8051:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
        !          8052:       k3= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
        !          8053:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
        !          8054:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
        !          8055:       Tresult[nres][k4+1]=Tvalsel[k3];
        !          8056:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];
        !          8057:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
        !          8058:       k4++;;
        !          8059:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
        !          8060:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
        !          8061:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
        !          8062:       Tqresult[nres][k4q+1]=Tvalsel[k3q];
        !          8063:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q];
        !          8064:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
        !          8065:       k4q++;;
        !          8066:     }
        !          8067:   }
1.234     brouard  8068:   
1.235   ! brouard  8069:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8070:   return (0);
                   8071: }
1.235   ! brouard  8072: 
1.230     brouard  8073: int decodemodel( char model[], int lastobs)
                   8074:  /**< This routine decodes the model and returns:
1.224     brouard  8075:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8076:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8077:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8078:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8079:        * - cptcovage number of covariates with age*products =2
                   8080:        * - cptcovs number of simple covariates
                   8081:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8082:        *     which is a new column after the 9 (ncovcol) variables. 
                   8083:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8084:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8085:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8086:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8087:        */
1.136     brouard  8088: {
1.145     brouard  8089:   int i, j, k, ks;
1.227     brouard  8090:   int  j1, k1, k2, k3, k4;
1.136     brouard  8091:   char modelsav[80];
1.145     brouard  8092:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8093:   char *strpt;
1.136     brouard  8094: 
1.145     brouard  8095:   /*removespace(model);*/
1.136     brouard  8096:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8097:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8098:     if (strstr(model,"AGE") !=0){
1.192     brouard  8099:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8100:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8101:       return 1;
                   8102:     }
1.141     brouard  8103:     if (strstr(model,"v") !=0){
                   8104:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8105:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8106:       return 1;
                   8107:     }
1.187     brouard  8108:     strcpy(modelsav,model); 
                   8109:     if ((strpt=strstr(model,"age*age")) !=0){
                   8110:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8111:       if(strpt != model){
1.234     brouard  8112:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8113:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8114:  corresponding column of parameters.\n",model);
1.234     brouard  8115:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8116:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8117:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8118:        return 1;
1.225     brouard  8119:       }
1.187     brouard  8120:       nagesqr=1;
                   8121:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8122:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8123:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8124:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8125:       else 
1.234     brouard  8126:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8127:     }else
                   8128:       nagesqr=0;
                   8129:     if (strlen(modelsav) >1){
                   8130:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8131:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8132:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8133:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8134:                     * cst, age and age*age 
                   8135:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8136:       /* including age products which are counted in cptcovage.
                   8137:        * but the covariates which are products must be treated 
                   8138:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8139:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8140:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8141:       
                   8142:       
1.187     brouard  8143:       /*   Design
                   8144:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8145:        *  <          ncovcol=8                >
                   8146:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8147:        *   k=  1    2      3       4     5       6      7        8
                   8148:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8149:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8150:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8151:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8152:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8153:        *  Tage[++cptcovage]=k
                   8154:        *       if products, new covar are created after ncovcol with k1
                   8155:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8156:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8157:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8158:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8159:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8160:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8161:        *  <          ncovcol=8                >
                   8162:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8163:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8164:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8165:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8166:        * p Tprod[1]@2={                         6, 5}
                   8167:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8168:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8169:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8170:        *How to reorganize?
                   8171:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8172:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8173:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8174:        * Struct []
                   8175:        */
1.225     brouard  8176:       
1.187     brouard  8177:       /* This loop fills the array Tvar from the string 'model'.*/
                   8178:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8179:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8180:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8181:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8182:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8183:       /*       k=1 Tvar[1]=2 (from V2) */
                   8184:       /*       k=5 Tvar[5] */
                   8185:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8186:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8187:       /*       } */
1.198     brouard  8188:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8189:       /*
                   8190:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8191:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8192:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8193:       }
1.187     brouard  8194:       cptcovage=0;
                   8195:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8196:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8197:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8198:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8199:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8200:        /*scanf("%d",i);*/
                   8201:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8202:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8203:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8204:            /* covar is not filled and then is empty */
                   8205:            cptcovprod--;
                   8206:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8207:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8208:            Typevar[k]=1;  /* 1 for age product */
                   8209:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8210:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8211:            /*printf("stre=%s ", stre);*/
                   8212:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8213:            cptcovprod--;
                   8214:            cutl(stre,strb,strc,'V');
                   8215:            Tvar[k]=atoi(stre);
                   8216:            Typevar[k]=1;  /* 1 for age product */
                   8217:            cptcovage++;
                   8218:            Tage[cptcovage]=k;
                   8219:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8220:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8221:            cptcovn++;
                   8222:            cptcovprodnoage++;k1++;
                   8223:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8224:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8225:                                                because this model-covariate is a construction we invent a new column
                   8226:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8227:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8228:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8229:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8230:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8231:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8232:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8233:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8234:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8235:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8236:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8237:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8238:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8239:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8240:            for (i=1; i<=lastobs;i++){
                   8241:              /* Computes the new covariate which is a product of
                   8242:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8243:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8244:            }
                   8245:          } /* End age is not in the model */
                   8246:        } /* End if model includes a product */
                   8247:        else { /* no more sum */
                   8248:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8249:          /*  scanf("%d",i);*/
                   8250:          cutl(strd,strc,strb,'V');
                   8251:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8252:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8253:          Tvar[k]=atoi(strd);
                   8254:          Typevar[k]=0;  /* 0 for simple covariates */
                   8255:        }
                   8256:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8257:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8258:                                  scanf("%d",i);*/
1.187     brouard  8259:       } /* end of loop + on total covariates */
                   8260:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8261:   } /* end if strlen(model == 0) */
1.136     brouard  8262:   
                   8263:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8264:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8265:   
1.136     brouard  8266:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8267:      printf("cptcovprod=%d ", cptcovprod);
                   8268:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8269:      scanf("%d ",i);*/
                   8270: 
                   8271: 
1.230     brouard  8272: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8273:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8274: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8275:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8276:    k =           1    2   3     4       5       6      7      8        9
                   8277:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8278:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8279:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8280:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8281:          Tmodelind[combination of covar]=k;
1.225     brouard  8282: */  
                   8283: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8284:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8285:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8286:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8287:   printf("Model=%s\n\
                   8288: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8289: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8290: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8291:   fprintf(ficlog,"Model=%s\n\
                   8292: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8293: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8294: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8295: 
1.234     brouard  8296:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8297:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8298:       Fixed[k]= 0;
                   8299:       Dummy[k]= 0;
1.225     brouard  8300:       ncoveff++;
1.232     brouard  8301:       ncovf++;
1.234     brouard  8302:       nsd++;
                   8303:       modell[k].maintype= FTYPE;
                   8304:       TvarsD[nsd]=Tvar[k];
                   8305:       TvarsDind[nsd]=k;
                   8306:       TvarF[ncovf]=Tvar[k];
                   8307:       TvarFind[ncovf]=k;
                   8308:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8309:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8310:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8311:       Fixed[k]= 0;
                   8312:       Dummy[k]= 0;
                   8313:       ncoveff++;
                   8314:       ncovf++;
                   8315:       modell[k].maintype= FTYPE;
                   8316:       TvarF[ncovf]=Tvar[k];
                   8317:       TvarFind[ncovf]=k;
1.230     brouard  8318:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8319:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8320:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){ /* Remind that product Vn*Vm are added in k*/ /* Only simple fixed quantitative variable */
1.227     brouard  8321:       Fixed[k]= 0;
                   8322:       Dummy[k]= 1;
1.230     brouard  8323:       nqfveff++;
1.234     brouard  8324:       modell[k].maintype= FTYPE;
                   8325:       modell[k].subtype= FQ;
                   8326:       nsq++;
                   8327:       TvarsQ[nsq]=Tvar[k];
                   8328:       TvarsQind[nsq]=k;
1.232     brouard  8329:       ncovf++;
1.234     brouard  8330:       TvarF[ncovf]=Tvar[k];
                   8331:       TvarFind[ncovf]=k;
1.231     brouard  8332:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8333:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.234     brouard  8334:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying variables */
1.227     brouard  8335:       Fixed[k]= 1;
                   8336:       Dummy[k]= 0;
1.225     brouard  8337:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8338:       modell[k].maintype= VTYPE;
                   8339:       modell[k].subtype= VD;
                   8340:       nsd++;
                   8341:       TvarsD[nsd]=Tvar[k];
                   8342:       TvarsDind[nsd]=k;
                   8343:       ncovv++; /* Only simple time varying variables */
                   8344:       TvarV[ncovv]=Tvar[k];
                   8345:       TvarVind[ncovv]=k;
1.231     brouard  8346:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8347:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8348:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8349:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8350:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8351:       Fixed[k]= 1;
                   8352:       Dummy[k]= 1;
                   8353:       nqtveff++;
                   8354:       modell[k].maintype= VTYPE;
                   8355:       modell[k].subtype= VQ;
                   8356:       ncovv++; /* Only simple time varying variables */
                   8357:       nsq++;
                   8358:       TvarsQ[nsq]=Tvar[k];
                   8359:       TvarsQind[nsq]=k;
                   8360:       TvarV[ncovv]=Tvar[k];
                   8361:       TvarVind[ncovv]=k;
1.231     brouard  8362:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8363:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8364:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8365:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8366:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8367:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8368:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8369:       ncova++;
                   8370:       TvarA[ncova]=Tvar[k];
                   8371:       TvarAind[ncova]=k;
1.231     brouard  8372:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.234     brouard  8373:        Fixed[k]= 2;
                   8374:        Dummy[k]= 2;
                   8375:        modell[k].maintype= ATYPE;
                   8376:        modell[k].subtype= APFD;
                   8377:        /* ncoveff++; */
1.227     brouard  8378:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.234     brouard  8379:        Fixed[k]= 2;
                   8380:        Dummy[k]= 3;
                   8381:        modell[k].maintype= ATYPE;
                   8382:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8383:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8384:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.234     brouard  8385:        Fixed[k]= 3;
                   8386:        Dummy[k]= 2;
                   8387:        modell[k].maintype= ATYPE;
                   8388:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8389:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8390:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.234     brouard  8391:        Fixed[k]= 3;
                   8392:        Dummy[k]= 3;
                   8393:        modell[k].maintype= ATYPE;
                   8394:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8395:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8396:       }
                   8397:     }else if (Typevar[k] == 2) {  /* product without age */
                   8398:       k1=Tposprod[k];
                   8399:       if(Tvard[k1][1] <=ncovcol){
1.234     brouard  8400:        if(Tvard[k1][2] <=ncovcol){
                   8401:          Fixed[k]= 1;
                   8402:          Dummy[k]= 0;
                   8403:          modell[k].maintype= FTYPE;
                   8404:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8405:          ncovf++; /* Fixed variables without age */
                   8406:          TvarF[ncovf]=Tvar[k];
                   8407:          TvarFind[ncovf]=k;
                   8408:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8409:          Fixed[k]= 0;  /* or 2 ?*/
                   8410:          Dummy[k]= 1;
                   8411:          modell[k].maintype= FTYPE;
                   8412:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8413:          ncovf++; /* Varying variables without age */
                   8414:          TvarF[ncovf]=Tvar[k];
                   8415:          TvarFind[ncovf]=k;
                   8416:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8417:          Fixed[k]= 1;
                   8418:          Dummy[k]= 0;
                   8419:          modell[k].maintype= VTYPE;
                   8420:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8421:          ncovv++; /* Varying variables without age */
                   8422:          TvarV[ncovv]=Tvar[k];
                   8423:          TvarVind[ncovv]=k;
                   8424:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8425:          Fixed[k]= 1;
                   8426:          Dummy[k]= 1;
                   8427:          modell[k].maintype= VTYPE;
                   8428:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8429:          ncovv++; /* Varying variables without age */
                   8430:          TvarV[ncovv]=Tvar[k];
                   8431:          TvarVind[ncovv]=k;
                   8432:        } 
1.227     brouard  8433:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.234     brouard  8434:        if(Tvard[k1][2] <=ncovcol){
                   8435:          Fixed[k]= 0;  /* or 2 ?*/
                   8436:          Dummy[k]= 1;
                   8437:          modell[k].maintype= FTYPE;
                   8438:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8439:          ncovf++; /* Fixed variables without age */
                   8440:          TvarF[ncovf]=Tvar[k];
                   8441:          TvarFind[ncovf]=k;
                   8442:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8443:          Fixed[k]= 1;
                   8444:          Dummy[k]= 1;
                   8445:          modell[k].maintype= VTYPE;
                   8446:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8447:          ncovv++; /* Varying variables without age */
                   8448:          TvarV[ncovv]=Tvar[k];
                   8449:          TvarVind[ncovv]=k;
                   8450:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8451:          Fixed[k]= 1;
                   8452:          Dummy[k]= 1;
                   8453:          modell[k].maintype= VTYPE;
                   8454:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8455:          ncovv++; /* Varying variables without age */
                   8456:          TvarV[ncovv]=Tvar[k];
                   8457:          TvarVind[ncovv]=k;
                   8458:          ncovv++; /* Varying variables without age */
                   8459:          TvarV[ncovv]=Tvar[k];
                   8460:          TvarVind[ncovv]=k;
                   8461:        } 
1.227     brouard  8462:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.234     brouard  8463:        if(Tvard[k1][2] <=ncovcol){
                   8464:          Fixed[k]= 1;
                   8465:          Dummy[k]= 1;
                   8466:          modell[k].maintype= VTYPE;
                   8467:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8468:          ncovv++; /* Varying variables without age */
                   8469:          TvarV[ncovv]=Tvar[k];
                   8470:          TvarVind[ncovv]=k;
                   8471:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8472:          Fixed[k]= 1;
                   8473:          Dummy[k]= 1;
                   8474:          modell[k].maintype= VTYPE;
                   8475:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8476:          ncovv++; /* Varying variables without age */
                   8477:          TvarV[ncovv]=Tvar[k];
                   8478:          TvarVind[ncovv]=k;
                   8479:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8480:          Fixed[k]= 1;
                   8481:          Dummy[k]= 0;
                   8482:          modell[k].maintype= VTYPE;
                   8483:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8484:          ncovv++; /* Varying variables without age */
                   8485:          TvarV[ncovv]=Tvar[k];
                   8486:          TvarVind[ncovv]=k;
                   8487:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8488:          Fixed[k]= 1;
                   8489:          Dummy[k]= 1;
                   8490:          modell[k].maintype= VTYPE;
                   8491:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   8492:          ncovv++; /* Varying variables without age */
                   8493:          TvarV[ncovv]=Tvar[k];
                   8494:          TvarVind[ncovv]=k;
                   8495:        } 
1.227     brouard  8496:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.234     brouard  8497:        if(Tvard[k1][2] <=ncovcol){
                   8498:          Fixed[k]= 1;
                   8499:          Dummy[k]= 1;
                   8500:          modell[k].maintype= VTYPE;
                   8501:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   8502:          ncovv++; /* Varying variables without age */
                   8503:          TvarV[ncovv]=Tvar[k];
                   8504:          TvarVind[ncovv]=k;
                   8505:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8506:          Fixed[k]= 1;
                   8507:          Dummy[k]= 1;
                   8508:          modell[k].maintype= VTYPE;
                   8509:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   8510:          ncovv++; /* Varying variables without age */
                   8511:          TvarV[ncovv]=Tvar[k];
                   8512:          TvarVind[ncovv]=k;
                   8513:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8514:          Fixed[k]= 1;
                   8515:          Dummy[k]= 1;
                   8516:          modell[k].maintype= VTYPE;
                   8517:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   8518:          ncovv++; /* Varying variables without age */
                   8519:          TvarV[ncovv]=Tvar[k];
                   8520:          TvarVind[ncovv]=k;
                   8521:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8522:          Fixed[k]= 1;
                   8523:          Dummy[k]= 1;
                   8524:          modell[k].maintype= VTYPE;
                   8525:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   8526:          ncovv++; /* Varying variables without age */
                   8527:          TvarV[ncovv]=Tvar[k];
                   8528:          TvarVind[ncovv]=k;
                   8529:        } 
1.227     brouard  8530:       }else{
1.234     brouard  8531:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   8532:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
1.226     brouard  8533:       } /* end k1 */
1.225     brouard  8534:     }else{
1.226     brouard  8535:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   8536:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  8537:     }
1.227     brouard  8538:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  8539:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  8540:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   8541:   }
                   8542:   /* Searching for doublons in the model */
                   8543:   for(k1=1; k1<= cptcovt;k1++){
                   8544:     for(k2=1; k2 <k1;k2++){
                   8545:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  8546:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   8547:          if(Tvar[k1]==Tvar[k2]){
                   8548:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8549:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8550:            return(1);
                   8551:          }
                   8552:        }else if (Typevar[k1] ==2){
                   8553:          k3=Tposprod[k1];
                   8554:          k4=Tposprod[k2];
                   8555:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   8556:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8557:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8558:            return(1);
                   8559:          }
                   8560:        }
1.227     brouard  8561:       }
                   8562:     }
1.225     brouard  8563:   }
                   8564:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   8565:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  8566:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   8567:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  8568:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  8569:   /*endread:*/
1.225     brouard  8570:   printf("Exiting decodemodel: ");
                   8571:   return (1);
1.136     brouard  8572: }
                   8573: 
1.169     brouard  8574: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.136     brouard  8575: {
                   8576:   int i, m;
1.218     brouard  8577:   int firstone=0;
                   8578:   
1.136     brouard  8579:   for (i=1; i<=imx; i++) {
                   8580:     for(m=2; (m<= maxwav); m++) {
                   8581:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   8582:        anint[m][i]=9999;
1.216     brouard  8583:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   8584:          s[m][i]=-1;
1.136     brouard  8585:       }
                   8586:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  8587:        *nberr = *nberr + 1;
1.218     brouard  8588:        if(firstone == 0){
                   8589:          firstone=1;
                   8590:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   8591:        }
                   8592:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  8593:        s[m][i]=-1;
                   8594:       }
                   8595:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  8596:        (*nberr)++;
1.136     brouard  8597:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   8598:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   8599:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   8600:       }
                   8601:     }
                   8602:   }
                   8603: 
                   8604:   for (i=1; i<=imx; i++)  {
                   8605:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   8606:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  8607:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  8608:        if (s[m][i] >= nlstate+1) {
1.169     brouard  8609:          if(agedc[i]>0){
                   8610:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  8611:              agev[m][i]=agedc[i];
1.214     brouard  8612:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  8613:            }else {
1.136     brouard  8614:              if ((int)andc[i]!=9999){
                   8615:                nbwarn++;
                   8616:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   8617:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   8618:                agev[m][i]=-1;
                   8619:              }
                   8620:            }
1.169     brouard  8621:          } /* agedc > 0 */
1.214     brouard  8622:        } /* end if */
1.136     brouard  8623:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   8624:                                 years but with the precision of a month */
                   8625:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   8626:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   8627:            agev[m][i]=1;
                   8628:          else if(agev[m][i] < *agemin){ 
                   8629:            *agemin=agev[m][i];
                   8630:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   8631:          }
                   8632:          else if(agev[m][i] >*agemax){
                   8633:            *agemax=agev[m][i];
1.156     brouard  8634:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  8635:          }
                   8636:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   8637:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  8638:        } /* en if 9*/
1.136     brouard  8639:        else { /* =9 */
1.214     brouard  8640:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  8641:          agev[m][i]=1;
                   8642:          s[m][i]=-1;
                   8643:        }
                   8644:       }
1.214     brouard  8645:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  8646:        agev[m][i]=1;
1.214     brouard  8647:       else{
                   8648:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8649:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8650:        agev[m][i]=0;
                   8651:       }
                   8652:     } /* End for lastpass */
                   8653:   }
1.136     brouard  8654:     
                   8655:   for (i=1; i<=imx; i++)  {
                   8656:     for(m=firstpass; (m<=lastpass); m++){
                   8657:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  8658:        (*nberr)++;
1.136     brouard  8659:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8660:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8661:        return 1;
                   8662:       }
                   8663:     }
                   8664:   }
                   8665: 
                   8666:   /*for (i=1; i<=imx; i++){
                   8667:   for (m=firstpass; (m<lastpass); m++){
                   8668:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   8669: }
                   8670: 
                   8671: }*/
                   8672: 
                   8673: 
1.139     brouard  8674:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   8675:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  8676: 
                   8677:   return (0);
1.164     brouard  8678:  /* endread:*/
1.136     brouard  8679:     printf("Exiting calandcheckages: ");
                   8680:     return (1);
                   8681: }
                   8682: 
1.172     brouard  8683: #if defined(_MSC_VER)
                   8684: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8685: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8686: //#include "stdafx.h"
                   8687: //#include <stdio.h>
                   8688: //#include <tchar.h>
                   8689: //#include <windows.h>
                   8690: //#include <iostream>
                   8691: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   8692: 
                   8693: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8694: 
                   8695: BOOL IsWow64()
                   8696: {
                   8697:        BOOL bIsWow64 = FALSE;
                   8698: 
                   8699:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   8700:        //  (HANDLE, PBOOL);
                   8701: 
                   8702:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8703: 
                   8704:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   8705:        const char funcName[] = "IsWow64Process";
                   8706:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   8707:                GetProcAddress(module, funcName);
                   8708: 
                   8709:        if (NULL != fnIsWow64Process)
                   8710:        {
                   8711:                if (!fnIsWow64Process(GetCurrentProcess(),
                   8712:                        &bIsWow64))
                   8713:                        //throw std::exception("Unknown error");
                   8714:                        printf("Unknown error\n");
                   8715:        }
                   8716:        return bIsWow64 != FALSE;
                   8717: }
                   8718: #endif
1.177     brouard  8719: 
1.191     brouard  8720: void syscompilerinfo(int logged)
1.167     brouard  8721:  {
                   8722:    /* #include "syscompilerinfo.h"*/
1.185     brouard  8723:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   8724:    /* /GS /W3 /Gy
                   8725:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   8726:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   8727:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  8728:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   8729:    */ 
                   8730:    /* 64 bits */
1.185     brouard  8731:    /*
                   8732:      /GS /W3 /Gy
                   8733:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   8734:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   8735:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   8736:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   8737:    /* Optimization are useless and O3 is slower than O2 */
                   8738:    /*
                   8739:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   8740:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   8741:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   8742:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   8743:    */
1.186     brouard  8744:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  8745:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   8746:       /PDB:"visual studio
                   8747:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   8748:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   8749:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   8750:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   8751:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   8752:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   8753:       uiAccess='false'"
                   8754:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   8755:       /NOLOGO /TLBID:1
                   8756:    */
1.177     brouard  8757: #if defined __INTEL_COMPILER
1.178     brouard  8758: #if defined(__GNUC__)
                   8759:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   8760: #endif
1.177     brouard  8761: #elif defined(__GNUC__) 
1.179     brouard  8762: #ifndef  __APPLE__
1.174     brouard  8763: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  8764: #endif
1.177     brouard  8765:    struct utsname sysInfo;
1.178     brouard  8766:    int cross = CROSS;
                   8767:    if (cross){
                   8768:           printf("Cross-");
1.191     brouard  8769:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  8770:    }
1.174     brouard  8771: #endif
                   8772: 
1.171     brouard  8773: #include <stdint.h>
1.178     brouard  8774: 
1.191     brouard  8775:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  8776: #if defined(__clang__)
1.191     brouard  8777:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  8778: #endif
                   8779: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  8780:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  8781: #endif
                   8782: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  8783:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  8784: #endif
                   8785: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  8786:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  8787: #endif
                   8788: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  8789:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  8790: #endif
                   8791: #if defined(_MSC_VER)
1.191     brouard  8792:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  8793: #endif
                   8794: #if defined(__PGI)
1.191     brouard  8795:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  8796: #endif
                   8797: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  8798:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  8799: #endif
1.191     brouard  8800:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  8801:    
1.167     brouard  8802: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   8803: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   8804:     // Windows (x64 and x86)
1.191     brouard  8805:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  8806: #elif __unix__ // all unices, not all compilers
                   8807:     // Unix
1.191     brouard  8808:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  8809: #elif __linux__
                   8810:     // linux
1.191     brouard  8811:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  8812: #elif __APPLE__
1.174     brouard  8813:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  8814:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  8815: #endif
                   8816: 
                   8817: /*  __MINGW32__          */
                   8818: /*  __CYGWIN__  */
                   8819: /* __MINGW64__  */
                   8820: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   8821: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   8822: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   8823: /* _WIN64  // Defined for applications for Win64. */
                   8824: /* _M_X64 // Defined for compilations that target x64 processors. */
                   8825: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  8826: 
1.167     brouard  8827: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  8828:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  8829: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  8830:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  8831: #else
1.191     brouard  8832:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  8833: #endif
                   8834: 
1.169     brouard  8835: #if defined(__GNUC__)
                   8836: # if defined(__GNUC_PATCHLEVEL__)
                   8837: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   8838:                             + __GNUC_MINOR__ * 100 \
                   8839:                             + __GNUC_PATCHLEVEL__)
                   8840: # else
                   8841: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   8842:                             + __GNUC_MINOR__ * 100)
                   8843: # endif
1.174     brouard  8844:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  8845:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  8846: 
                   8847:    if (uname(&sysInfo) != -1) {
                   8848:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  8849:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  8850:    }
                   8851:    else
                   8852:       perror("uname() error");
1.179     brouard  8853:    //#ifndef __INTEL_COMPILER 
                   8854: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  8855:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  8856:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  8857: #endif
1.169     brouard  8858: #endif
1.172     brouard  8859: 
                   8860:    //   void main()
                   8861:    //   {
1.169     brouard  8862: #if defined(_MSC_VER)
1.174     brouard  8863:    if (IsWow64()){
1.191     brouard  8864:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   8865:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  8866:    }
                   8867:    else{
1.191     brouard  8868:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   8869:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  8870:    }
1.172     brouard  8871:    //     printf("\nPress Enter to continue...");
                   8872:    //     getchar();
                   8873:    //   }
                   8874: 
1.169     brouard  8875: #endif
                   8876:    
1.167     brouard  8877: 
1.219     brouard  8878: }
1.136     brouard  8879: 
1.219     brouard  8880: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  8881:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235   ! brouard  8882:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  8883:   /* double ftolpl = 1.e-10; */
1.180     brouard  8884:   double age, agebase, agelim;
1.203     brouard  8885:   double tot;
1.180     brouard  8886: 
1.202     brouard  8887:   strcpy(filerespl,"PL_");
                   8888:   strcat(filerespl,fileresu);
                   8889:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   8890:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   8891:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   8892:   }
1.227     brouard  8893:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   8894:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  8895:   pstamp(ficrespl);
1.203     brouard  8896:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  8897:   fprintf(ficrespl,"#Age ");
                   8898:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   8899:   fprintf(ficrespl,"\n");
1.180     brouard  8900:   
1.219     brouard  8901:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  8902: 
1.219     brouard  8903:   agebase=ageminpar;
                   8904:   agelim=agemaxpar;
1.180     brouard  8905: 
1.227     brouard  8906:   /* i1=pow(2,ncoveff); */
1.234     brouard  8907:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  8908:   if (cptcovn < 1){i1=1;}
1.180     brouard  8909: 
1.235   ! brouard  8910:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.220     brouard  8911:   for(k=1; k<=i1;k++){
1.235   ! brouard  8912:     if(TKresult[nres]!= k)
        !          8913:       continue;
        !          8914: 
1.220     brouard  8915:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
1.180     brouard  8916:     /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
1.219     brouard  8917:     //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
1.220     brouard  8918:     /* k=k+1; */
1.219     brouard  8919:     /* to clean */
                   8920:     //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   8921:     fprintf(ficrespl,"#******");
                   8922:     printf("#******");
                   8923:     fprintf(ficlog,"#******");
1.227     brouard  8924:     for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   8925:       fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
1.219     brouard  8926:       printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8927:       fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8928:     }
1.235   ! brouard  8929:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          8930:       printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          8931:       fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          8932:     }
1.219     brouard  8933:     fprintf(ficrespl,"******\n");
                   8934:     printf("******\n");
                   8935:     fprintf(ficlog,"******\n");
1.227     brouard  8936:     if(invalidvarcomb[k]){
                   8937:       printf("\nCombination (%d) ignored because no case \n",k); 
                   8938:       fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   8939:       fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
1.220     brouard  8940:                                                continue;
1.227     brouard  8941:     }
1.219     brouard  8942: 
                   8943:     fprintf(ficrespl,"#Age ");
1.227     brouard  8944:     for(j=1;j<=cptcoveff;j++) {
1.219     brouard  8945:       fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8946:     }
                   8947:     for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   8948:     fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  8949:     
1.219     brouard  8950:     for (age=agebase; age<=agelim; age++){
                   8951:       /* for (age=agebase; age<=agebase; age++){ */
1.235   ! brouard  8952:       prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
1.219     brouard  8953:       fprintf(ficrespl,"%.0f ",age );
1.227     brouard  8954:       for(j=1;j<=cptcoveff;j++)
                   8955:        fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.219     brouard  8956:       tot=0.;
                   8957:       for(i=1; i<=nlstate;i++){
1.227     brouard  8958:        tot +=  prlim[i][i];
                   8959:        fprintf(ficrespl," %.5f", prlim[i][i]);
1.219     brouard  8960:       }
                   8961:       fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   8962:     } /* Age */
                   8963:     /* was end of cptcod */
                   8964:   } /* cptcov */
                   8965:   return 0;
1.180     brouard  8966: }
                   8967: 
1.218     brouard  8968: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   8969:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   8970:        
                   8971:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   8972:    * at any age between ageminpar and agemaxpar
                   8973:         */
1.235   ! brouard  8974:   int i, j, k, i1, nres=0 ;
1.217     brouard  8975:   /* double ftolpl = 1.e-10; */
                   8976:   double age, agebase, agelim;
                   8977:   double tot;
1.218     brouard  8978:   /* double ***mobaverage; */
                   8979:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  8980: 
                   8981:   strcpy(fileresplb,"PLB_");
                   8982:   strcat(fileresplb,fileresu);
                   8983:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   8984:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   8985:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   8986:   }
                   8987:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   8988:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   8989:   pstamp(ficresplb);
                   8990:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   8991:   fprintf(ficresplb,"#Age ");
                   8992:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   8993:   fprintf(ficresplb,"\n");
                   8994:   
1.218     brouard  8995:   
                   8996:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   8997:   
                   8998:   agebase=ageminpar;
                   8999:   agelim=agemaxpar;
                   9000:   
                   9001:   
1.227     brouard  9002:   i1=pow(2,cptcoveff);
1.218     brouard  9003:   if (cptcovn < 1){i1=1;}
1.227     brouard  9004:   
1.235   ! brouard  9005:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          9006:   for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
        !          9007:     if(TKresult[nres]!= k)
        !          9008:       continue;
1.218     brouard  9009:     //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9010:     fprintf(ficresplb,"#******");
                   9011:     printf("#******");
                   9012:     fprintf(ficlog,"#******");
1.227     brouard  9013:     for(j=1;j<=cptcoveff ;j++) {/* all covariates */
1.218     brouard  9014:       fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9015:       printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9016:       fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9017:     }
1.235   ! brouard  9018:     for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
        !          9019:       printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          9020:       fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          9021:       fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          9022:     }
1.218     brouard  9023:     fprintf(ficresplb,"******\n");
                   9024:     printf("******\n");
                   9025:     fprintf(ficlog,"******\n");
1.227     brouard  9026:     if(invalidvarcomb[k]){
                   9027:       printf("\nCombination (%d) ignored because no cases \n",k); 
                   9028:       fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9029:       fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9030:       continue;
                   9031:     }
1.218     brouard  9032:     
                   9033:     fprintf(ficresplb,"#Age ");
1.227     brouard  9034:     for(j=1;j<=cptcoveff;j++) {
1.218     brouard  9035:       fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9036:     }
                   9037:     for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9038:     fprintf(ficresplb,"Total Years_to_converge\n");
                   9039:     
                   9040:     
                   9041:     for (age=agebase; age<=agelim; age++){
                   9042:       /* for (age=agebase; age<=agebase; age++){ */
                   9043:       if(mobilavproj > 0){
                   9044:        /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9045:        /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.227     brouard  9046:        bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k);
1.218     brouard  9047:       }else if (mobilavproj == 0){
1.227     brouard  9048:        printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9049:        fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9050:        exit(1);
1.218     brouard  9051:       }else{
1.227     brouard  9052:        /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9053:        bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k);
1.218     brouard  9054:       }
                   9055:       fprintf(ficresplb,"%.0f ",age );
1.227     brouard  9056:       for(j=1;j<=cptcoveff;j++)
                   9057:        fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.218     brouard  9058:       tot=0.;
                   9059:       for(i=1; i<=nlstate;i++){
1.227     brouard  9060:        tot +=  bprlim[i][i];
                   9061:        fprintf(ficresplb," %.5f", bprlim[i][i]);
1.218     brouard  9062:       }
                   9063:       fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9064:     } /* Age */
                   9065:     /* was end of cptcod */
                   9066:   } /* cptcov */
                   9067:   
                   9068:   /* hBijx(p, bage, fage); */
                   9069:   /* fclose(ficrespijb); */
                   9070:   
                   9071:   return 0;
1.217     brouard  9072: }
1.218     brouard  9073:  
1.180     brouard  9074: int hPijx(double *p, int bage, int fage){
                   9075:     /*------------- h Pij x at various ages ------------*/
                   9076: 
                   9077:   int stepsize;
                   9078:   int agelim;
                   9079:   int hstepm;
                   9080:   int nhstepm;
1.235   ! brouard  9081:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9082: 
                   9083:   double agedeb;
                   9084:   double ***p3mat;
                   9085: 
1.201     brouard  9086:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9087:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9088:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9089:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9090:     }
                   9091:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9092:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9093:   
                   9094:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9095:     /*if (stepm<=24) stepsize=2;*/
                   9096: 
                   9097:     agelim=AGESUP;
                   9098:     hstepm=stepsize*YEARM; /* Every year of age */
                   9099:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9100:                
1.180     brouard  9101:     /* hstepm=1;   aff par mois*/
                   9102:     pstamp(ficrespij);
                   9103:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9104:     i1= pow(2,cptcoveff);
1.218     brouard  9105:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9106:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9107:                /*      k=k+1;  */
1.235   ! brouard  9108:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          9109:     for(k=1; k<=i1;k++){
        !          9110:       if(TKresult[nres]!= k)
        !          9111:        continue;
1.183     brouard  9112:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9113:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9114:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235   ! brouard  9115:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          9116:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          9117:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          9118:       }
1.183     brouard  9119:       fprintf(ficrespij,"******\n");
                   9120:       
                   9121:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9122:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9123:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9124:        
                   9125:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9126:        
1.183     brouard  9127:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9128:        oldm=oldms;savm=savms;
1.235   ! brouard  9129:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9130:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9131:        for(i=1; i<=nlstate;i++)
                   9132:          for(j=1; j<=nlstate+ndeath;j++)
                   9133:            fprintf(ficrespij," %1d-%1d",i,j);
                   9134:        fprintf(ficrespij,"\n");
                   9135:        for (h=0; h<=nhstepm; h++){
                   9136:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9137:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9138:          for(i=1; i<=nlstate;i++)
                   9139:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9140:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9141:          fprintf(ficrespij,"\n");
                   9142:        }
1.183     brouard  9143:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9144:        fprintf(ficrespij,"\n");
                   9145:       }
1.180     brouard  9146:       /*}*/
                   9147:     }
1.218     brouard  9148:     return 0;
1.180     brouard  9149: }
1.218     brouard  9150:  
                   9151:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9152:     /*------------- h Bij x at various ages ------------*/
                   9153: 
                   9154:   int stepsize;
1.218     brouard  9155:   /* int agelim; */
                   9156:        int ageminl;
1.217     brouard  9157:   int hstepm;
                   9158:   int nhstepm;
                   9159:   int h, i, i1, j, k;
1.218     brouard  9160:        
1.217     brouard  9161:   double agedeb;
                   9162:   double ***p3mat;
1.218     brouard  9163:        
                   9164:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9165:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9166:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9167:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9168:   }
                   9169:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9170:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9171:   
                   9172:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9173:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9174:   
1.218     brouard  9175:   /* agelim=AGESUP; */
                   9176:   ageminl=30;
                   9177:   hstepm=stepsize*YEARM; /* Every year of age */
                   9178:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9179:   
                   9180:   /* hstepm=1;   aff par mois*/
                   9181:   pstamp(ficrespijb);
                   9182:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  9183:   i1= pow(2,cptcoveff);
1.218     brouard  9184:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9185:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9186:   /*   k=k+1;  */
1.227     brouard  9187:   for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.218     brouard  9188:     fprintf(ficrespijb,"\n#****** ");
1.227     brouard  9189:     for(j=1;j<=cptcoveff;j++)
1.218     brouard  9190:       fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9191:     fprintf(ficrespijb,"******\n");
1.222     brouard  9192:     if(invalidvarcomb[k]){
                   9193:       fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9194:       continue;
                   9195:     }
1.218     brouard  9196:     
                   9197:     /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9198:     for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9199:       /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9200:       nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9201:       nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9202:       
                   9203:       /*         nhstepm=nhstepm*YEARM; aff par mois*/
                   9204:       
                   9205:       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9206:       /* oldm=oldms;savm=savms; */
                   9207:       /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9208:       hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9209:       /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   9210:       fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
                   9211:       for(i=1; i<=nlstate;i++)
                   9212:        for(j=1; j<=nlstate+ndeath;j++)
                   9213:          fprintf(ficrespijb," %1d-%1d",i,j);
                   9214:       fprintf(ficrespijb,"\n");
                   9215:       for (h=0; h<=nhstepm; h++){
                   9216:        /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9217:        fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9218:        /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
1.217     brouard  9219:        for(i=1; i<=nlstate;i++)
                   9220:          for(j=1; j<=nlstate+ndeath;j++)
1.218     brouard  9221:            fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
1.217     brouard  9222:        fprintf(ficrespijb,"\n");
                   9223:       }
1.218     brouard  9224:       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9225:       fprintf(ficrespijb,"\n");
1.217     brouard  9226:     }
1.218     brouard  9227:     /*}*/
                   9228:   }
                   9229:   return 0;
                   9230:  } /*  hBijx */
1.217     brouard  9231: 
1.180     brouard  9232: 
1.136     brouard  9233: /***********************************************/
                   9234: /**************** Main Program *****************/
                   9235: /***********************************************/
                   9236: 
                   9237: int main(int argc, char *argv[])
                   9238: {
                   9239: #ifdef GSL
                   9240:   const gsl_multimin_fminimizer_type *T;
                   9241:   size_t iteri = 0, it;
                   9242:   int rval = GSL_CONTINUE;
                   9243:   int status = GSL_SUCCESS;
                   9244:   double ssval;
                   9245: #endif
                   9246:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9247:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9248:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9249:   int jj, ll, li, lj, lk;
1.136     brouard  9250:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9251:   int num_filled;
1.136     brouard  9252:   int itimes;
                   9253:   int NDIM=2;
                   9254:   int vpopbased=0;
1.235   ! brouard  9255:   int nres=0;
1.136     brouard  9256: 
1.164     brouard  9257:   char ca[32], cb[32];
1.136     brouard  9258:   /*  FILE *fichtm; *//* Html File */
                   9259:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9260:   struct stat info;
1.191     brouard  9261:   double agedeb=0.;
1.194     brouard  9262: 
                   9263:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9264:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9265: 
1.165     brouard  9266:   double fret;
1.191     brouard  9267:   double dum=0.; /* Dummy variable */
1.136     brouard  9268:   double ***p3mat;
1.218     brouard  9269:   /* double ***mobaverage; */
1.164     brouard  9270: 
                   9271:   char line[MAXLINE];
1.197     brouard  9272:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9273: 
1.234     brouard  9274:   char  modeltemp[MAXLINE];
1.230     brouard  9275:   char resultline[MAXLINE];
                   9276:   
1.136     brouard  9277:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9278:   char *tok, *val; /* pathtot */
1.136     brouard  9279:   int firstobs=1, lastobs=10;
1.195     brouard  9280:   int c,  h , cpt, c2;
1.191     brouard  9281:   int jl=0;
                   9282:   int i1, j1, jk, stepsize=0;
1.194     brouard  9283:   int count=0;
                   9284: 
1.164     brouard  9285:   int *tab; 
1.136     brouard  9286:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9287:   int backcast=0;
1.136     brouard  9288:   int mobilav=0,popforecast=0;
1.191     brouard  9289:   int hstepm=0, nhstepm=0;
1.136     brouard  9290:   int agemortsup;
                   9291:   float  sumlpop=0.;
                   9292:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9293:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9294: 
1.191     brouard  9295:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9296:   double ftolpl=FTOL;
                   9297:   double **prlim;
1.217     brouard  9298:   double **bprlim;
1.136     brouard  9299:   double ***param; /* Matrix of parameters */
                   9300:   double  *p;
                   9301:   double **matcov; /* Matrix of covariance */
1.203     brouard  9302:   double **hess; /* Hessian matrix */
1.136     brouard  9303:   double ***delti3; /* Scale */
                   9304:   double *delti; /* Scale */
                   9305:   double ***eij, ***vareij;
                   9306:   double **varpl; /* Variances of prevalence limits by age */
                   9307:   double *epj, vepp;
1.164     brouard  9308: 
1.136     brouard  9309:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9310:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9311: 
1.136     brouard  9312:   double **ximort;
1.145     brouard  9313:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9314:   int *dcwave;
                   9315: 
1.164     brouard  9316:   char z[1]="c";
1.136     brouard  9317: 
                   9318:   /*char  *strt;*/
                   9319:   char strtend[80];
1.126     brouard  9320: 
1.164     brouard  9321: 
1.126     brouard  9322: /*   setlocale (LC_ALL, ""); */
                   9323: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9324: /*   textdomain (PACKAGE); */
                   9325: /*   setlocale (LC_CTYPE, ""); */
                   9326: /*   setlocale (LC_MESSAGES, ""); */
                   9327: 
                   9328:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9329:   rstart_time = time(NULL);  
                   9330:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9331:   start_time = *localtime(&rstart_time);
1.126     brouard  9332:   curr_time=start_time;
1.157     brouard  9333:   /*tml = *localtime(&start_time.tm_sec);*/
                   9334:   /* strcpy(strstart,asctime(&tml)); */
                   9335:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9336: 
                   9337: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9338: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9339: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9340: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9341: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9342: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9343: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9344: /*   strt=asctime(&tmg); */
                   9345: /*   printf("Time(after) =%s",strstart);  */
                   9346: /*  (void) time (&time_value);
                   9347: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9348: *  tm = *localtime(&time_value);
                   9349: *  strstart=asctime(&tm);
                   9350: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9351: */
                   9352: 
                   9353:   nberr=0; /* Number of errors and warnings */
                   9354:   nbwarn=0;
1.184     brouard  9355: #ifdef WIN32
                   9356:   _getcwd(pathcd, size);
                   9357: #else
1.126     brouard  9358:   getcwd(pathcd, size);
1.184     brouard  9359: #endif
1.191     brouard  9360:   syscompilerinfo(0);
1.196     brouard  9361:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9362:   if(argc <=1){
                   9363:     printf("\nEnter the parameter file name: ");
1.205     brouard  9364:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9365:       printf("ERROR Empty parameter file name\n");
                   9366:       goto end;
                   9367:     }
1.126     brouard  9368:     i=strlen(pathr);
                   9369:     if(pathr[i-1]=='\n')
                   9370:       pathr[i-1]='\0';
1.156     brouard  9371:     i=strlen(pathr);
1.205     brouard  9372:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9373:       pathr[i-1]='\0';
1.205     brouard  9374:     }
                   9375:     i=strlen(pathr);
                   9376:     if( i==0 ){
                   9377:       printf("ERROR Empty parameter file name\n");
                   9378:       goto end;
                   9379:     }
                   9380:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9381:       printf("Pathr |%s|\n",pathr);
                   9382:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9383:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9384:       strcpy (pathtot, val);
                   9385:       if(pathr[0] == '\0') break; /* Dirty */
                   9386:     }
                   9387:   }
                   9388:   else{
                   9389:     strcpy(pathtot,argv[1]);
                   9390:   }
                   9391:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9392:   /*cygwin_split_path(pathtot,path,optionfile);
                   9393:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9394:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9395: 
                   9396:   /* Split argv[0], imach program to get pathimach */
                   9397:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9398:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9399:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9400:  /*   strcpy(pathimach,argv[0]); */
                   9401:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9402:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9403:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9404: #ifdef WIN32
                   9405:   _chdir(path); /* Can be a relative path */
                   9406:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9407: #else
1.126     brouard  9408:   chdir(path); /* Can be a relative path */
1.184     brouard  9409:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9410: #endif
                   9411:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9412:   strcpy(command,"mkdir ");
                   9413:   strcat(command,optionfilefiname);
                   9414:   if((outcmd=system(command)) != 0){
1.169     brouard  9415:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9416:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9417:     /* fclose(ficlog); */
                   9418: /*     exit(1); */
                   9419:   }
                   9420: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9421: /*     perror("mkdir"); */
                   9422: /*   } */
                   9423: 
                   9424:   /*-------- arguments in the command line --------*/
                   9425: 
1.186     brouard  9426:   /* Main Log file */
1.126     brouard  9427:   strcat(filelog, optionfilefiname);
                   9428:   strcat(filelog,".log");    /* */
                   9429:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9430:     printf("Problem with logfile %s\n",filelog);
                   9431:     goto end;
                   9432:   }
                   9433:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9434:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9435:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9436:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9437:  path=%s \n\
                   9438:  optionfile=%s\n\
                   9439:  optionfilext=%s\n\
1.156     brouard  9440:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9441: 
1.197     brouard  9442:   syscompilerinfo(1);
1.167     brouard  9443: 
1.126     brouard  9444:   printf("Local time (at start):%s",strstart);
                   9445:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9446:   fflush(ficlog);
                   9447: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9448: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9449: 
                   9450:   /* */
                   9451:   strcpy(fileres,"r");
                   9452:   strcat(fileres, optionfilefiname);
1.201     brouard  9453:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9454:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9455:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9456: 
1.186     brouard  9457:   /* Main ---------arguments file --------*/
1.126     brouard  9458: 
                   9459:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9460:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9461:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9462:     fflush(ficlog);
1.149     brouard  9463:     /* goto end; */
                   9464:     exit(70); 
1.126     brouard  9465:   }
                   9466: 
                   9467: 
                   9468: 
                   9469:   strcpy(filereso,"o");
1.201     brouard  9470:   strcat(filereso,fileresu);
1.126     brouard  9471:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9472:     printf("Problem with Output resultfile: %s\n", filereso);
                   9473:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9474:     fflush(ficlog);
                   9475:     goto end;
                   9476:   }
                   9477: 
                   9478:   /* Reads comments: lines beginning with '#' */
                   9479:   numlinepar=0;
1.197     brouard  9480: 
                   9481:     /* First parameter line */
                   9482:   while(fgets(line, MAXLINE, ficpar)) {
                   9483:     /* If line starts with a # it is a comment */
                   9484:     if (line[0] == '#') {
                   9485:       numlinepar++;
                   9486:       fputs(line,stdout);
                   9487:       fputs(line,ficparo);
                   9488:       fputs(line,ficlog);
                   9489:       continue;
                   9490:     }else
                   9491:       break;
                   9492:   }
                   9493:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   9494:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   9495:     if (num_filled != 5) {
                   9496:       printf("Should be 5 parameters\n");
                   9497:     }
1.126     brouard  9498:     numlinepar++;
1.197     brouard  9499:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   9500:   }
                   9501:   /* Second parameter line */
                   9502:   while(fgets(line, MAXLINE, ficpar)) {
                   9503:     /* If line starts with a # it is a comment */
                   9504:     if (line[0] == '#') {
                   9505:       numlinepar++;
                   9506:       fputs(line,stdout);
                   9507:       fputs(line,ficparo);
                   9508:       fputs(line,ficlog);
                   9509:       continue;
                   9510:     }else
                   9511:       break;
                   9512:   }
1.223     brouard  9513:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   9514:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   9515:     if (num_filled != 11) {
                   9516:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  9517:       printf("but line=%s\n",line);
1.197     brouard  9518:     }
1.223     brouard  9519:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  9520:   }
1.203     brouard  9521:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  9522:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  9523:   /* Third parameter line */
                   9524:   while(fgets(line, MAXLINE, ficpar)) {
                   9525:     /* If line starts with a # it is a comment */
                   9526:     if (line[0] == '#') {
                   9527:       numlinepar++;
                   9528:       fputs(line,stdout);
                   9529:       fputs(line,ficparo);
                   9530:       fputs(line,ficlog);
                   9531:       continue;
                   9532:     }else
                   9533:       break;
                   9534:   }
1.201     brouard  9535:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   9536:     if (num_filled == 0)
                   9537:             model[0]='\0';
                   9538:     else if (num_filled != 1){
1.197     brouard  9539:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9540:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9541:       model[0]='\0';
                   9542:       goto end;
                   9543:     }
                   9544:     else{
                   9545:       if (model[0]=='+'){
                   9546:        for(i=1; i<=strlen(model);i++)
                   9547:          modeltemp[i-1]=model[i];
1.201     brouard  9548:        strcpy(model,modeltemp); 
1.197     brouard  9549:       }
                   9550:     }
1.199     brouard  9551:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  9552:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  9553:   }
                   9554:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   9555:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   9556:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  9557:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   9558:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  9559:   fflush(ficlog);
1.190     brouard  9560:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   9561:   if(model[0]=='#'){
1.187     brouard  9562:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   9563:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   9564:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   9565:     if(mle != -1){
                   9566:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   9567:       exit(1);
                   9568:     }
                   9569:   }
1.126     brouard  9570:   while((c=getc(ficpar))=='#' && c!= EOF){
                   9571:     ungetc(c,ficpar);
                   9572:     fgets(line, MAXLINE, ficpar);
                   9573:     numlinepar++;
1.195     brouard  9574:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   9575:       z[0]=line[1];
                   9576:     }
                   9577:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  9578:     fputs(line, stdout);
                   9579:     //puts(line);
1.126     brouard  9580:     fputs(line,ficparo);
                   9581:     fputs(line,ficlog);
                   9582:   }
                   9583:   ungetc(c,ficpar);
                   9584: 
                   9585:    
1.145     brouard  9586:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  9587:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  9588:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  9589:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  9590:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   9591:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   9592:      v1+v2*age+v2*v3 makes cptcovn = 3
                   9593:   */
                   9594:   if (strlen(model)>1) 
1.187     brouard  9595:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  9596:   else
1.187     brouard  9597:     ncovmodel=2; /* Constant and age */
1.133     brouard  9598:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   9599:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  9600:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   9601:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9602:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9603:     fflush(stdout);
                   9604:     fclose (ficlog);
                   9605:     goto end;
                   9606:   }
1.126     brouard  9607:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9608:   delti=delti3[1][1];
                   9609:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   9610:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
                   9611:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  9612:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   9613:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9614:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   9615:     fclose (ficparo);
                   9616:     fclose (ficlog);
                   9617:     goto end;
                   9618:     exit(0);
1.220     brouard  9619:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  9620:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  9621:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   9622:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9623:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9624:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9625:     hess=matrix(1,npar,1,npar);
1.220     brouard  9626:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  9627:     /* Read guessed parameters */
1.126     brouard  9628:     /* Reads comments: lines beginning with '#' */
                   9629:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9630:       ungetc(c,ficpar);
                   9631:       fgets(line, MAXLINE, ficpar);
                   9632:       numlinepar++;
1.141     brouard  9633:       fputs(line,stdout);
1.126     brouard  9634:       fputs(line,ficparo);
                   9635:       fputs(line,ficlog);
                   9636:     }
                   9637:     ungetc(c,ficpar);
                   9638:     
                   9639:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9640:     for(i=1; i <=nlstate; i++){
1.234     brouard  9641:       j=0;
1.126     brouard  9642:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  9643:        if(jj==i) continue;
                   9644:        j++;
                   9645:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9646:        if ((i1 != i) || (j1 != jj)){
                   9647:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  9648: It might be a problem of design; if ncovcol and the model are correct\n \
                   9649: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  9650:          exit(1);
                   9651:        }
                   9652:        fprintf(ficparo,"%1d%1d",i1,j1);
                   9653:        if(mle==1)
                   9654:          printf("%1d%1d",i,jj);
                   9655:        fprintf(ficlog,"%1d%1d",i,jj);
                   9656:        for(k=1; k<=ncovmodel;k++){
                   9657:          fscanf(ficpar," %lf",&param[i][j][k]);
                   9658:          if(mle==1){
                   9659:            printf(" %lf",param[i][j][k]);
                   9660:            fprintf(ficlog," %lf",param[i][j][k]);
                   9661:          }
                   9662:          else
                   9663:            fprintf(ficlog," %lf",param[i][j][k]);
                   9664:          fprintf(ficparo," %lf",param[i][j][k]);
                   9665:        }
                   9666:        fscanf(ficpar,"\n");
                   9667:        numlinepar++;
                   9668:        if(mle==1)
                   9669:          printf("\n");
                   9670:        fprintf(ficlog,"\n");
                   9671:        fprintf(ficparo,"\n");
1.126     brouard  9672:       }
                   9673:     }  
                   9674:     fflush(ficlog);
1.234     brouard  9675:     
1.145     brouard  9676:     /* Reads scales values */
1.126     brouard  9677:     p=param[1][1];
                   9678:     
                   9679:     /* Reads comments: lines beginning with '#' */
                   9680:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9681:       ungetc(c,ficpar);
                   9682:       fgets(line, MAXLINE, ficpar);
                   9683:       numlinepar++;
1.141     brouard  9684:       fputs(line,stdout);
1.126     brouard  9685:       fputs(line,ficparo);
                   9686:       fputs(line,ficlog);
                   9687:     }
                   9688:     ungetc(c,ficpar);
                   9689: 
                   9690:     for(i=1; i <=nlstate; i++){
                   9691:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  9692:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9693:        if ( (i1-i) * (j1-j) != 0){
                   9694:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   9695:          exit(1);
                   9696:        }
                   9697:        printf("%1d%1d",i,j);
                   9698:        fprintf(ficparo,"%1d%1d",i1,j1);
                   9699:        fprintf(ficlog,"%1d%1d",i1,j1);
                   9700:        for(k=1; k<=ncovmodel;k++){
                   9701:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   9702:          printf(" %le",delti3[i][j][k]);
                   9703:          fprintf(ficparo," %le",delti3[i][j][k]);
                   9704:          fprintf(ficlog," %le",delti3[i][j][k]);
                   9705:        }
                   9706:        fscanf(ficpar,"\n");
                   9707:        numlinepar++;
                   9708:        printf("\n");
                   9709:        fprintf(ficparo,"\n");
                   9710:        fprintf(ficlog,"\n");
1.126     brouard  9711:       }
                   9712:     }
                   9713:     fflush(ficlog);
1.234     brouard  9714:     
1.145     brouard  9715:     /* Reads covariance matrix */
1.126     brouard  9716:     delti=delti3[1][1];
1.220     brouard  9717:                
                   9718:                
1.126     brouard  9719:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  9720:                
1.126     brouard  9721:     /* Reads comments: lines beginning with '#' */
                   9722:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9723:       ungetc(c,ficpar);
                   9724:       fgets(line, MAXLINE, ficpar);
                   9725:       numlinepar++;
1.141     brouard  9726:       fputs(line,stdout);
1.126     brouard  9727:       fputs(line,ficparo);
                   9728:       fputs(line,ficlog);
                   9729:     }
                   9730:     ungetc(c,ficpar);
1.220     brouard  9731:                
1.126     brouard  9732:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9733:     hess=matrix(1,npar,1,npar);
1.131     brouard  9734:     for(i=1; i <=npar; i++)
                   9735:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  9736:                
1.194     brouard  9737:     /* Scans npar lines */
1.126     brouard  9738:     for(i=1; i <=npar; i++){
1.226     brouard  9739:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  9740:       if(count != 3){
1.226     brouard  9741:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  9742: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   9743: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  9744:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  9745: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   9746: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  9747:        exit(1);
1.220     brouard  9748:       }else{
1.226     brouard  9749:        if(mle==1)
                   9750:          printf("%1d%1d%d",i1,j1,jk);
                   9751:       }
                   9752:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   9753:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  9754:       for(j=1; j <=i; j++){
1.226     brouard  9755:        fscanf(ficpar," %le",&matcov[i][j]);
                   9756:        if(mle==1){
                   9757:          printf(" %.5le",matcov[i][j]);
                   9758:        }
                   9759:        fprintf(ficlog," %.5le",matcov[i][j]);
                   9760:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  9761:       }
                   9762:       fscanf(ficpar,"\n");
                   9763:       numlinepar++;
                   9764:       if(mle==1)
1.220     brouard  9765:                                printf("\n");
1.126     brouard  9766:       fprintf(ficlog,"\n");
                   9767:       fprintf(ficparo,"\n");
                   9768:     }
1.194     brouard  9769:     /* End of read covariance matrix npar lines */
1.126     brouard  9770:     for(i=1; i <=npar; i++)
                   9771:       for(j=i+1;j<=npar;j++)
1.226     brouard  9772:        matcov[i][j]=matcov[j][i];
1.126     brouard  9773:     
                   9774:     if(mle==1)
                   9775:       printf("\n");
                   9776:     fprintf(ficlog,"\n");
                   9777:     
                   9778:     fflush(ficlog);
                   9779:     
                   9780:     /*-------- Rewriting parameter file ----------*/
                   9781:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   9782:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   9783:     strcat(rfileres,".");    /* */
                   9784:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   9785:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  9786:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   9787:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  9788:     }
                   9789:     fprintf(ficres,"#%s\n",version);
                   9790:   }    /* End of mle != -3 */
1.218     brouard  9791:   
1.186     brouard  9792:   /*  Main data
                   9793:    */
1.126     brouard  9794:   n= lastobs;
                   9795:   num=lvector(1,n);
                   9796:   moisnais=vector(1,n);
                   9797:   annais=vector(1,n);
                   9798:   moisdc=vector(1,n);
                   9799:   andc=vector(1,n);
1.220     brouard  9800:   weight=vector(1,n);
1.126     brouard  9801:   agedc=vector(1,n);
                   9802:   cod=ivector(1,n);
1.220     brouard  9803:   for(i=1;i<=n;i++){
1.234     brouard  9804:     num[i]=0;
                   9805:     moisnais[i]=0;
                   9806:     annais[i]=0;
                   9807:     moisdc[i]=0;
                   9808:     andc[i]=0;
                   9809:     agedc[i]=0;
                   9810:     cod[i]=0;
                   9811:     weight[i]=1.0; /* Equal weights, 1 by default */
                   9812:   }
1.126     brouard  9813:   mint=matrix(1,maxwav,1,n);
                   9814:   anint=matrix(1,maxwav,1,n);
1.131     brouard  9815:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  9816:   tab=ivector(1,NCOVMAX);
1.144     brouard  9817:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  9818:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  9819: 
1.136     brouard  9820:   /* Reads data from file datafile */
                   9821:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   9822:     goto end;
                   9823: 
                   9824:   /* Calculation of the number of parameters from char model */
1.234     brouard  9825:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  9826:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   9827:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   9828:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   9829:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  9830:   */
                   9831:   
                   9832:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   9833:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   9834:   TvarsD=ivector(1,NCOVMAX); /*  */
                   9835:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   9836:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  9837:   TvarF=ivector(1,NCOVMAX); /*  */
                   9838:   TvarFind=ivector(1,NCOVMAX); /*  */
                   9839:   TvarV=ivector(1,NCOVMAX); /*  */
                   9840:   TvarVind=ivector(1,NCOVMAX); /*  */
                   9841:   TvarA=ivector(1,NCOVMAX); /*  */
                   9842:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  9843:   TvarFD=ivector(1,NCOVMAX); /*  */
                   9844:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   9845:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   9846:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   9847:   TvarVD=ivector(1,NCOVMAX); /*  */
                   9848:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   9849:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   9850:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   9851: 
1.230     brouard  9852:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  9853:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  9854:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   9855:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   9856:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  9857:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   9858:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   9859:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   9860:   */
                   9861:   /* For model-covariate k tells which data-covariate to use but
                   9862:     because this model-covariate is a construction we invent a new column
                   9863:     ncovcol + k1
                   9864:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   9865:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  9866:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   9867:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  9868:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   9869:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  9870:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  9871:   */
1.145     brouard  9872:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   9873:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  9874:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   9875:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  9876:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  9877:                         4 covariates (3 plus signs)
                   9878:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   9879:                      */  
1.230     brouard  9880:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  9881:                                * individual dummy, fixed or varying:
                   9882:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   9883:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  9884:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   9885:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   9886:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   9887:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   9888:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  9889:                                * individual quantitative, fixed or varying:
                   9890:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   9891:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   9892:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  9893: /* Main decodemodel */
                   9894: 
1.187     brouard  9895: 
1.223     brouard  9896:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  9897:     goto end;
                   9898: 
1.137     brouard  9899:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   9900:     nbwarn++;
                   9901:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   9902:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   9903:   }
1.136     brouard  9904:     /*  if(mle==1){*/
1.137     brouard  9905:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   9906:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  9907:   }
                   9908: 
                   9909:     /*-calculation of age at interview from date of interview and age at death -*/
                   9910:   agev=matrix(1,maxwav,1,imx);
                   9911: 
                   9912:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   9913:     goto end;
                   9914: 
1.126     brouard  9915: 
1.136     brouard  9916:   agegomp=(int)agemin;
                   9917:   free_vector(moisnais,1,n);
                   9918:   free_vector(annais,1,n);
1.126     brouard  9919:   /* free_matrix(mint,1,maxwav,1,n);
                   9920:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  9921:   /* free_vector(moisdc,1,n); */
                   9922:   /* free_vector(andc,1,n); */
1.145     brouard  9923:   /* */
                   9924:   
1.126     brouard  9925:   wav=ivector(1,imx);
1.214     brouard  9926:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9927:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9928:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   9929:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   9930:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   9931:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  9932:    
                   9933:   /* Concatenates waves */
1.214     brouard  9934:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   9935:      Death is a valid wave (if date is known).
                   9936:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   9937:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   9938:      and mw[mi+1][i]. dh depends on stepm.
                   9939:   */
                   9940: 
1.126     brouard  9941:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.145     brouard  9942:   /* */
                   9943:  
1.215     brouard  9944:   free_vector(moisdc,1,n);
                   9945:   free_vector(andc,1,n);
                   9946: 
1.126     brouard  9947:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   9948:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   9949:   ncodemax[1]=1;
1.145     brouard  9950:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  9951:   cptcoveff=0;
1.220     brouard  9952:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   9953:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  9954:   }
                   9955:   
                   9956:   ncovcombmax=pow(2,cptcoveff);
                   9957:   invalidvarcomb=ivector(1, ncovcombmax); 
                   9958:   for(i=1;i<ncovcombmax;i++)
                   9959:     invalidvarcomb[i]=0;
                   9960:   
1.211     brouard  9961:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  9962:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  9963:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  9964:   
1.200     brouard  9965:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  9966:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  9967:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  9968:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   9969:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   9970:    * (currently 0 or 1) in the data.
                   9971:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   9972:    * corresponding modality (h,j).
                   9973:    */
                   9974: 
1.145     brouard  9975:   h=0;
                   9976:   /*if (cptcovn > 0) */
1.126     brouard  9977:   m=pow(2,cptcoveff);
                   9978:  
1.144     brouard  9979:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  9980:           * For k=4 covariates, h goes from 1 to m=2**k
                   9981:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   9982:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  9983:           *     h\k   1     2     3     4
1.143     brouard  9984:           *______________________________  
                   9985:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   9986:           *     2     2     1     1     1
                   9987:           *     3 i=2 1     2     1     1
                   9988:           *     4     2     2     1     1
                   9989:           *     5 i=3 1 i=2 1     2     1
                   9990:           *     6     2     1     2     1
                   9991:           *     7 i=4 1     2     2     1
                   9992:           *     8     2     2     2     1
1.197     brouard  9993:           *     9 i=5 1 i=3 1 i=2 1     2
                   9994:           *    10     2     1     1     2
                   9995:           *    11 i=6 1     2     1     2
                   9996:           *    12     2     2     1     2
                   9997:           *    13 i=7 1 i=4 1     2     2    
                   9998:           *    14     2     1     2     2
                   9999:           *    15 i=8 1     2     2     2
                   10000:           *    16     2     2     2     2
1.143     brouard  10001:           */
1.212     brouard  10002:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10003:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10004:      * and the value of each covariate?
                   10005:      * V1=1, V2=1, V3=2, V4=1 ?
                   10006:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10007:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10008:      * In order to get the real value in the data, we use nbcode
                   10009:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10010:      * We are keeping this crazy system in order to be able (in the future?) 
                   10011:      * to have more than 2 values (0 or 1) for a covariate.
                   10012:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10013:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10014:      *              bbbbbbbb
                   10015:      *              76543210     
                   10016:      *   h-1        00000101 (6-1=5)
1.219     brouard  10017:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10018:      *           &
                   10019:      *     1        00000001 (1)
1.219     brouard  10020:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10021:      *          +1= 00000001 =1 
1.211     brouard  10022:      *
                   10023:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10024:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10025:      *    >>k'            11
                   10026:      *          &   00000001
                   10027:      *            = 00000001
                   10028:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10029:      * Reverse h=6 and m=16?
                   10030:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10031:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10032:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10033:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10034:      * V3=decodtabm(14,3,2**4)=2
                   10035:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10036:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10037:      *          &1 000000001
                   10038:      *           = 000000001
                   10039:      *         +1= 000000010 =2
                   10040:      *                  2211
                   10041:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10042:      *                  V3=2
1.220     brouard  10043:                 * codtabm and decodtabm are identical
1.211     brouard  10044:      */
                   10045: 
1.145     brouard  10046: 
                   10047:  free_ivector(Ndum,-1,NCOVMAX);
                   10048: 
                   10049: 
1.126     brouard  10050:     
1.186     brouard  10051:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10052:   strcpy(optionfilegnuplot,optionfilefiname);
                   10053:   if(mle==-3)
1.201     brouard  10054:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10055:   strcat(optionfilegnuplot,".gp");
                   10056: 
                   10057:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10058:     printf("Problem with file %s",optionfilegnuplot);
                   10059:   }
                   10060:   else{
1.204     brouard  10061:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10062:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10063:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10064:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10065:   }
                   10066:   /*  fclose(ficgp);*/
1.186     brouard  10067: 
                   10068: 
                   10069:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10070: 
                   10071:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10072:   if(mle==-3)
1.201     brouard  10073:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10074:   strcat(optionfilehtm,".htm");
                   10075:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10076:     printf("Problem with %s \n",optionfilehtm);
                   10077:     exit(0);
1.126     brouard  10078:   }
                   10079: 
                   10080:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10081:   strcat(optionfilehtmcov,"-cov.htm");
                   10082:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10083:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10084:   }
                   10085:   else{
                   10086:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10087: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10088: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10089:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10090:   }
                   10091: 
1.213     brouard  10092:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10093: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10094: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10095: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10096: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10097: \n\
                   10098: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10099:  <ul><li><h4>Parameter files</h4>\n\
                   10100:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10101:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10102:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10103:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10104:  - Date and time at start: %s</ul>\n",\
                   10105:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10106:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10107:          fileres,fileres,\
                   10108:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10109:   fflush(fichtm);
                   10110: 
                   10111:   strcpy(pathr,path);
                   10112:   strcat(pathr,optionfilefiname);
1.184     brouard  10113: #ifdef WIN32
                   10114:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10115: #else
1.126     brouard  10116:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10117: #endif
                   10118:          
1.126     brouard  10119:   
1.220     brouard  10120:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10121:                 and for any valid combination of covariates
1.126     brouard  10122:      and prints on file fileres'p'. */
1.227     brouard  10123:   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
                   10124:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10125: 
                   10126:   fprintf(fichtm,"\n");
                   10127:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10128: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10129: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10130:          imx,agemin,agemax,jmin,jmax,jmean);
                   10131:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10132:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10133:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10134:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10135:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10136: 
1.126     brouard  10137:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10138:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10139:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10140: 
                   10141:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10142:   /* For mortality only */
1.126     brouard  10143:   if (mle==-3){
1.136     brouard  10144:     ximort=matrix(1,NDIM,1,NDIM); 
1.220     brouard  10145:                for(i=1;i<=NDIM;i++)
                   10146:                        for(j=1;j<=NDIM;j++)
                   10147:                                ximort[i][j]=0.;
1.186     brouard  10148:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10149:     cens=ivector(1,n);
                   10150:     ageexmed=vector(1,n);
                   10151:     agecens=vector(1,n);
                   10152:     dcwave=ivector(1,n);
1.223     brouard  10153:                
1.126     brouard  10154:     for (i=1; i<=imx; i++){
                   10155:       dcwave[i]=-1;
                   10156:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10157:        if (s[m][i]>nlstate) {
                   10158:          dcwave[i]=m;
                   10159:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10160:          break;
                   10161:        }
1.126     brouard  10162:     }
1.226     brouard  10163:     
1.126     brouard  10164:     for (i=1; i<=imx; i++) {
                   10165:       if (wav[i]>0){
1.226     brouard  10166:        ageexmed[i]=agev[mw[1][i]][i];
                   10167:        j=wav[i];
                   10168:        agecens[i]=1.; 
                   10169:        
                   10170:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10171:          agecens[i]=agev[mw[j][i]][i];
                   10172:          cens[i]= 1;
                   10173:        }else if (ageexmed[i]< 1) 
                   10174:          cens[i]= -1;
                   10175:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10176:          cens[i]=0 ;
1.126     brouard  10177:       }
                   10178:       else cens[i]=-1;
                   10179:     }
                   10180:     
                   10181:     for (i=1;i<=NDIM;i++) {
                   10182:       for (j=1;j<=NDIM;j++)
1.226     brouard  10183:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10184:     }
                   10185:     
1.145     brouard  10186:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10187:     /*printf("%lf %lf", p[1], p[2]);*/
                   10188:     
                   10189:     
1.136     brouard  10190: #ifdef GSL
                   10191:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10192: #else
1.126     brouard  10193:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10194: #endif
1.201     brouard  10195:     strcpy(filerespow,"POW-MORT_"); 
                   10196:     strcat(filerespow,fileresu);
1.126     brouard  10197:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10198:       printf("Problem with resultfile: %s\n", filerespow);
                   10199:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10200:     }
1.136     brouard  10201: #ifdef GSL
                   10202:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10203: #else
1.126     brouard  10204:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10205: #endif
1.126     brouard  10206:     /*  for (i=1;i<=nlstate;i++)
                   10207:        for(j=1;j<=nlstate+ndeath;j++)
                   10208:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10209:     */
                   10210:     fprintf(ficrespow,"\n");
1.136     brouard  10211: #ifdef GSL
                   10212:     /* gsl starts here */ 
                   10213:     T = gsl_multimin_fminimizer_nmsimplex;
                   10214:     gsl_multimin_fminimizer *sfm = NULL;
                   10215:     gsl_vector *ss, *x;
                   10216:     gsl_multimin_function minex_func;
                   10217: 
                   10218:     /* Initial vertex size vector */
                   10219:     ss = gsl_vector_alloc (NDIM);
                   10220:     
                   10221:     if (ss == NULL){
                   10222:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10223:     }
                   10224:     /* Set all step sizes to 1 */
                   10225:     gsl_vector_set_all (ss, 0.001);
                   10226: 
                   10227:     /* Starting point */
1.126     brouard  10228:     
1.136     brouard  10229:     x = gsl_vector_alloc (NDIM);
                   10230:     
                   10231:     if (x == NULL){
                   10232:       gsl_vector_free(ss);
                   10233:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10234:     }
                   10235:   
                   10236:     /* Initialize method and iterate */
                   10237:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10238:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10239:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10240:     gsl_vector_set(x, 0, p[1]);
                   10241:     gsl_vector_set(x, 1, p[2]);
                   10242: 
                   10243:     minex_func.f = &gompertz_f;
                   10244:     minex_func.n = NDIM;
                   10245:     minex_func.params = (void *)&p; /* ??? */
                   10246:     
                   10247:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10248:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10249:     
                   10250:     printf("Iterations beginning .....\n\n");
                   10251:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10252: 
                   10253:     iteri=0;
                   10254:     while (rval == GSL_CONTINUE){
                   10255:       iteri++;
                   10256:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10257:       
                   10258:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10259:       fflush(0);
                   10260:       
                   10261:       if (status) 
                   10262:         break;
                   10263:       
                   10264:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10265:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10266:       
                   10267:       if (rval == GSL_SUCCESS)
                   10268:         printf ("converged to a local maximum at\n");
                   10269:       
                   10270:       printf("%5d ", iteri);
                   10271:       for (it = 0; it < NDIM; it++){
                   10272:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10273:       }
                   10274:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10275:     }
                   10276:     
                   10277:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10278:     
                   10279:     gsl_vector_free(x); /* initial values */
                   10280:     gsl_vector_free(ss); /* inital step size */
                   10281:     for (it=0; it<NDIM; it++){
                   10282:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10283:       fprintf(ficrespow," %.12lf", p[it]);
                   10284:     }
                   10285:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10286: #endif
                   10287: #ifdef POWELL
                   10288:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10289: #endif  
1.126     brouard  10290:     fclose(ficrespow);
                   10291:     
1.203     brouard  10292:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10293: 
                   10294:     for(i=1; i <=NDIM; i++)
                   10295:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10296:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10297:     
                   10298:     printf("\nCovariance matrix\n ");
1.203     brouard  10299:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10300:     for(i=1; i <=NDIM; i++) {
                   10301:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10302:                                printf("%f ",matcov[i][j]);
                   10303:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10304:       }
1.203     brouard  10305:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10306:     }
                   10307:     
                   10308:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10309:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10310:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10311:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10312:     }
1.126     brouard  10313:     lsurv=vector(1,AGESUP);
                   10314:     lpop=vector(1,AGESUP);
                   10315:     tpop=vector(1,AGESUP);
                   10316:     lsurv[agegomp]=100000;
                   10317:     
                   10318:     for (k=agegomp;k<=AGESUP;k++) {
                   10319:       agemortsup=k;
                   10320:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10321:     }
                   10322:     
                   10323:     for (k=agegomp;k<agemortsup;k++)
                   10324:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10325:     
                   10326:     for (k=agegomp;k<agemortsup;k++){
                   10327:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10328:       sumlpop=sumlpop+lpop[k];
                   10329:     }
                   10330:     
                   10331:     tpop[agegomp]=sumlpop;
                   10332:     for (k=agegomp;k<(agemortsup-3);k++){
                   10333:       /*  tpop[k+1]=2;*/
                   10334:       tpop[k+1]=tpop[k]-lpop[k];
                   10335:     }
                   10336:     
                   10337:     
                   10338:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10339:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10340:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10341:     
                   10342:     
                   10343:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10344:                ageminpar=50;
                   10345:                agemaxpar=100;
1.194     brouard  10346:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10347:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10348: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10349: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10350:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10351: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10352: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10353:     }else{
                   10354:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10355:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10356:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10357:                }
1.201     brouard  10358:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10359:                     stepm, weightopt,\
                   10360:                     model,imx,p,matcov,agemortsup);
                   10361:     
                   10362:     free_vector(lsurv,1,AGESUP);
                   10363:     free_vector(lpop,1,AGESUP);
                   10364:     free_vector(tpop,1,AGESUP);
1.220     brouard  10365:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10366:     free_ivector(cens,1,n);
                   10367:     free_vector(agecens,1,n);
                   10368:     free_ivector(dcwave,1,n);
1.220     brouard  10369: #ifdef GSL
1.136     brouard  10370: #endif
1.186     brouard  10371:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10372:   /* Standard  */
                   10373:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10374:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10375:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10376:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10377:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10378:     for (k=1; k<=npar;k++)
                   10379:       printf(" %d %8.5f",k,p[k]);
                   10380:     printf("\n");
1.205     brouard  10381:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10382:       /* mlikeli uses func not funcone */
                   10383:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10384:     }
                   10385:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10386:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10387:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10388:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10389:     }
                   10390:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10391:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10392:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10393:     for (k=1; k<=npar;k++)
                   10394:       printf(" %d %8.5f",k,p[k]);
                   10395:     printf("\n");
                   10396:     
                   10397:     /*--------- results files --------------*/
1.224     brouard  10398:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10399:     
                   10400:     
                   10401:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10402:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10403:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10404:     for(i=1,jk=1; i <=nlstate; i++){
                   10405:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10406:        if (k != i) {
                   10407:          printf("%d%d ",i,k);
                   10408:          fprintf(ficlog,"%d%d ",i,k);
                   10409:          fprintf(ficres,"%1d%1d ",i,k);
                   10410:          for(j=1; j <=ncovmodel; j++){
                   10411:            printf("%12.7f ",p[jk]);
                   10412:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10413:            fprintf(ficres,"%12.7f ",p[jk]);
                   10414:            jk++; 
                   10415:          }
                   10416:          printf("\n");
                   10417:          fprintf(ficlog,"\n");
                   10418:          fprintf(ficres,"\n");
                   10419:        }
1.126     brouard  10420:       }
                   10421:     }
1.203     brouard  10422:     if(mle != 0){
                   10423:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10424:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10425:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10426:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10427:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10428:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10429:        for(k=1; k <=(nlstate+ndeath); k++){
                   10430:          if (k != i) {
                   10431:            printf("%d%d ",i,k);
                   10432:            fprintf(ficlog,"%d%d ",i,k);
                   10433:            for(j=1; j <=ncovmodel; j++){
                   10434:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10435:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10436:              jk++; 
                   10437:            }
                   10438:            printf("\n");
                   10439:            fprintf(ficlog,"\n");
                   10440:          }
                   10441:        }
1.193     brouard  10442:       }
1.203     brouard  10443:     } /* end of hesscov and Wald tests */
1.225     brouard  10444:     
1.203     brouard  10445:     /*  */
1.126     brouard  10446:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10447:     printf("# Scales (for hessian or gradient estimation)\n");
                   10448:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10449:     for(i=1,jk=1; i <=nlstate; i++){
                   10450:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10451:        if (j!=i) {
                   10452:          fprintf(ficres,"%1d%1d",i,j);
                   10453:          printf("%1d%1d",i,j);
                   10454:          fprintf(ficlog,"%1d%1d",i,j);
                   10455:          for(k=1; k<=ncovmodel;k++){
                   10456:            printf(" %.5e",delti[jk]);
                   10457:            fprintf(ficlog," %.5e",delti[jk]);
                   10458:            fprintf(ficres," %.5e",delti[jk]);
                   10459:            jk++;
                   10460:          }
                   10461:          printf("\n");
                   10462:          fprintf(ficlog,"\n");
                   10463:          fprintf(ficres,"\n");
                   10464:        }
1.126     brouard  10465:       }
                   10466:     }
                   10467:     
                   10468:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10469:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10470:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10471:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10472:     /* # 121 Var(a12)\n\ */
                   10473:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10474:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10475:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10476:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10477:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10478:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10479:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10480:     
                   10481:     
                   10482:     /* Just to have a covariance matrix which will be more understandable
                   10483:        even is we still don't want to manage dictionary of variables
                   10484:     */
                   10485:     for(itimes=1;itimes<=2;itimes++){
                   10486:       jj=0;
                   10487:       for(i=1; i <=nlstate; i++){
1.225     brouard  10488:        for(j=1; j <=nlstate+ndeath; j++){
                   10489:          if(j==i) continue;
                   10490:          for(k=1; k<=ncovmodel;k++){
                   10491:            jj++;
                   10492:            ca[0]= k+'a'-1;ca[1]='\0';
                   10493:            if(itimes==1){
                   10494:              if(mle>=1)
                   10495:                printf("#%1d%1d%d",i,j,k);
                   10496:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   10497:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   10498:            }else{
                   10499:              if(mle>=1)
                   10500:                printf("%1d%1d%d",i,j,k);
                   10501:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   10502:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   10503:            }
                   10504:            ll=0;
                   10505:            for(li=1;li <=nlstate; li++){
                   10506:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   10507:                if(lj==li) continue;
                   10508:                for(lk=1;lk<=ncovmodel;lk++){
                   10509:                  ll++;
                   10510:                  if(ll<=jj){
                   10511:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   10512:                    if(ll<jj){
                   10513:                      if(itimes==1){
                   10514:                        if(mle>=1)
                   10515:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10516:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10517:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10518:                      }else{
                   10519:                        if(mle>=1)
                   10520:                          printf(" %.5e",matcov[jj][ll]); 
                   10521:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   10522:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   10523:                      }
                   10524:                    }else{
                   10525:                      if(itimes==1){
                   10526:                        if(mle>=1)
                   10527:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   10528:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   10529:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   10530:                      }else{
                   10531:                        if(mle>=1)
                   10532:                          printf(" %.7e",matcov[jj][ll]); 
                   10533:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   10534:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   10535:                      }
                   10536:                    }
                   10537:                  }
                   10538:                } /* end lk */
                   10539:              } /* end lj */
                   10540:            } /* end li */
                   10541:            if(mle>=1)
                   10542:              printf("\n");
                   10543:            fprintf(ficlog,"\n");
                   10544:            fprintf(ficres,"\n");
                   10545:            numlinepar++;
                   10546:          } /* end k*/
                   10547:        } /*end j */
1.126     brouard  10548:       } /* end i */
                   10549:     } /* end itimes */
                   10550:     
                   10551:     fflush(ficlog);
                   10552:     fflush(ficres);
1.225     brouard  10553:     while(fgets(line, MAXLINE, ficpar)) {
                   10554:       /* If line starts with a # it is a comment */
                   10555:       if (line[0] == '#') {
                   10556:        numlinepar++;
                   10557:        fputs(line,stdout);
                   10558:        fputs(line,ficparo);
                   10559:        fputs(line,ficlog);
                   10560:        continue;
                   10561:       }else
                   10562:        break;
                   10563:     }
                   10564:     
1.209     brouard  10565:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   10566:     /*   ungetc(c,ficpar); */
                   10567:     /*   fgets(line, MAXLINE, ficpar); */
                   10568:     /*   fputs(line,stdout); */
                   10569:     /*   fputs(line,ficparo); */
                   10570:     /* } */
                   10571:     /* ungetc(c,ficpar); */
1.126     brouard  10572:     
                   10573:     estepm=0;
1.209     brouard  10574:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  10575:       
                   10576:       if (num_filled != 6) {
                   10577:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10578:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10579:        goto end;
                   10580:       }
                   10581:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   10582:     }
                   10583:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   10584:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   10585:     
1.209     brouard  10586:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  10587:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   10588:     if (fage <= 2) {
                   10589:       bage = ageminpar;
                   10590:       fage = agemaxpar;
                   10591:     }
                   10592:     
                   10593:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  10594:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   10595:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  10596:                
1.186     brouard  10597:     /* Other stuffs, more or less useful */    
1.126     brouard  10598:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10599:       ungetc(c,ficpar);
                   10600:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10601:       fputs(line,stdout);
1.126     brouard  10602:       fputs(line,ficparo);
                   10603:     }
                   10604:     ungetc(c,ficpar);
                   10605:     
                   10606:     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
                   10607:     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10608:     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10609:     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10610:     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10611:     
                   10612:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10613:       ungetc(c,ficpar);
                   10614:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10615:       fputs(line,stdout);
1.126     brouard  10616:       fputs(line,ficparo);
                   10617:     }
                   10618:     ungetc(c,ficpar);
                   10619:     
                   10620:     
                   10621:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   10622:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   10623:     
                   10624:     fscanf(ficpar,"pop_based=%d\n",&popbased);
1.193     brouard  10625:     fprintf(ficlog,"pop_based=%d\n",popbased);
1.126     brouard  10626:     fprintf(ficparo,"pop_based=%d\n",popbased);   
                   10627:     fprintf(ficres,"pop_based=%d\n",popbased);   
                   10628:     
                   10629:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10630:       ungetc(c,ficpar);
                   10631:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10632:       fputs(line,stdout);
1.126     brouard  10633:       fputs(line,ficparo);
                   10634:     }
                   10635:     ungetc(c,ficpar);
                   10636:     
                   10637:     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
                   10638:     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10639:     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10640:     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10641:     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10642:     /* day and month of proj2 are not used but only year anproj2.*/
                   10643:     
1.217     brouard  10644:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10645:       ungetc(c,ficpar);
                   10646:       fgets(line, MAXLINE, ficpar);
                   10647:       fputs(line,stdout);
                   10648:       fputs(line,ficparo);
                   10649:     }
                   10650:     ungetc(c,ficpar);
                   10651:     
                   10652:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.223     brouard  10653:     fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10654:     fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10655:     fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  10656:     /* day and month of proj2 are not used but only year anproj2.*/
1.126     brouard  10657:     
1.230     brouard  10658:     /* Results */
1.235   ! brouard  10659:     nresult=0;
1.230     brouard  10660:     while(fgets(line, MAXLINE, ficpar)) {
                   10661:       /* If line starts with a # it is a comment */
                   10662:       if (line[0] == '#') {
                   10663:        numlinepar++;
                   10664:        fputs(line,stdout);
                   10665:        fputs(line,ficparo);
                   10666:        fputs(line,ficlog);
                   10667:        continue;
                   10668:       }else
                   10669:        break;
                   10670:     }
                   10671:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   10672:       if (num_filled == 0)
                   10673:        resultline[0]='\0';
                   10674:       else if (num_filled != 1){
                   10675:        printf("ERROR %d: result line should be at minimum 'result=' %s\n",num_filled, line);
                   10676:       }
1.235   ! brouard  10677:       nresult++; /* Sum of resultlines */
        !          10678:       printf("Result %d: result=%s\n",nresult, resultline);
        !          10679:       if(nresult > MAXRESULTLINES){
        !          10680:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
        !          10681:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
        !          10682:        goto end;
        !          10683:       }
        !          10684:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.230     brouard  10685:       while(fgets(line, MAXLINE, ficpar)) {
                   10686:        /* If line starts with a # it is a comment */
                   10687:        if (line[0] == '#') {
                   10688:          numlinepar++;
                   10689:          fputs(line,stdout);
                   10690:          fputs(line,ficparo);
                   10691:          fputs(line,ficlog);
                   10692:          continue;
                   10693:        }else
                   10694:          break;
                   10695:       }
                   10696:       if (feof(ficpar))
                   10697:        break;
                   10698:       else{ /* Processess output results for this combination of covariate values */
                   10699:       }                                   
                   10700:     }
                   10701: 
                   10702: 
1.126     brouard  10703:     
1.230     brouard  10704:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  10705:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  10706:     
                   10707:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  10708:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  10709:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10710: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10711: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  10712:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10713: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10714: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10715:     }else{
1.218     brouard  10716:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  10717:     }
                   10718:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  10719:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   10720:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  10721:                
1.225     brouard  10722:     /*------------ free_vector  -------------*/
                   10723:     /*  chdir(path); */
1.220     brouard  10724:                
1.215     brouard  10725:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   10726:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   10727:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   10728:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  10729:     free_lvector(num,1,n);
                   10730:     free_vector(agedc,1,n);
                   10731:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   10732:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   10733:     fclose(ficparo);
                   10734:     fclose(ficres);
1.220     brouard  10735:                
                   10736:                
1.186     brouard  10737:     /* Other results (useful)*/
1.220     brouard  10738:                
                   10739:                
1.126     brouard  10740:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  10741:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   10742:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  10743:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  10744:     fclose(ficrespl);
                   10745: 
                   10746:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  10747:     /*#include "hpijx.h"*/
                   10748:     hPijx(p, bage, fage);
1.145     brouard  10749:     fclose(ficrespij);
1.227     brouard  10750:     
1.220     brouard  10751:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  10752:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  10753:     k=1;
1.126     brouard  10754:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  10755:     
1.219     brouard  10756:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  10757:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  10758:     for(i=1;i<=AGESUP;i++)
1.219     brouard  10759:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  10760:        for(k=1;k<=ncovcombmax;k++)
                   10761:          probs[i][j][k]=0.;
1.219     brouard  10762:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   10763:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   10764:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  10765:       for(i=1;i<=AGESUP;i++)
                   10766:        for(j=1;j<=nlstate;j++)
                   10767:          for(k=1;k<=ncovcombmax;k++)
                   10768:            mobaverages[i][j][k]=0.;
1.219     brouard  10769:       mobaverage=mobaverages;
                   10770:       if (mobilav!=0) {
1.235   ! brouard  10771:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  10772:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   10773:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   10774:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   10775:        }
1.219     brouard  10776:       }
                   10777:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   10778:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   10779:       else if (mobilavproj !=0) {
1.235   ! brouard  10780:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  10781:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   10782:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   10783:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   10784:        }
1.219     brouard  10785:       }
                   10786:     }/* end if moving average */
1.227     brouard  10787:     
1.126     brouard  10788:     /*---------- Forecasting ------------------*/
                   10789:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   10790:     if(prevfcast==1){
                   10791:       /*    if(stepm ==1){*/
1.225     brouard  10792:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  10793:     }
1.217     brouard  10794:     if(backcast==1){
1.219     brouard  10795:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   10796:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   10797:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   10798: 
                   10799:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10800: 
                   10801:       bprlim=matrix(1,nlstate,1,nlstate);
                   10802:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   10803:       fclose(ficresplb);
                   10804: 
1.222     brouard  10805:       hBijx(p, bage, fage, mobaverage);
                   10806:       fclose(ficrespijb);
1.219     brouard  10807:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   10808: 
                   10809:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  10810:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  10811:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10812:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10813:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10814:     }
1.217     brouard  10815:     
1.186     brouard  10816:  
                   10817:     /* ------ Other prevalence ratios------------ */
1.126     brouard  10818: 
1.215     brouard  10819:     free_ivector(wav,1,imx);
                   10820:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   10821:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   10822:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  10823:                
                   10824:                
1.127     brouard  10825:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  10826:                
1.201     brouard  10827:     strcpy(filerese,"E_");
                   10828:     strcat(filerese,fileresu);
1.126     brouard  10829:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   10830:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   10831:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   10832:     }
1.208     brouard  10833:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   10834:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.219     brouard  10835:                
1.235   ! brouard  10836:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
        !          10837:     if (cptcovn < 1){i1=1;}
        !          10838:     
        !          10839:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          10840:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
        !          10841:       if(TKresult[nres]!= k)
        !          10842:        continue;
1.219     brouard  10843:       fprintf(ficreseij,"\n#****** ");
1.235   ! brouard  10844:       printf("\n#****** ");
1.225     brouard  10845:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  10846:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235   ! brouard  10847:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
        !          10848:       }
        !          10849:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
        !          10850:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          10851:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  10852:       }
                   10853:       fprintf(ficreseij,"******\n");
1.235   ! brouard  10854:       printf("******\n");
1.219     brouard  10855:       
                   10856:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10857:       oldm=oldms;savm=savms;
1.235   ! brouard  10858:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  10859:       
1.219     brouard  10860:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  10861:     }
                   10862:     fclose(ficreseij);
1.208     brouard  10863:     printf("done evsij\n");fflush(stdout);
                   10864:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  10865:                
1.227     brouard  10866:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  10867:                
                   10868:                
1.201     brouard  10869:     strcpy(filerest,"T_");
                   10870:     strcat(filerest,fileresu);
1.127     brouard  10871:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   10872:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   10873:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   10874:     }
1.208     brouard  10875:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   10876:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  10877:                
1.126     brouard  10878: 
1.201     brouard  10879:     strcpy(fileresstde,"STDE_");
                   10880:     strcat(fileresstde,fileresu);
1.126     brouard  10881:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  10882:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   10883:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  10884:     }
1.227     brouard  10885:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   10886:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  10887: 
1.201     brouard  10888:     strcpy(filerescve,"CVE_");
                   10889:     strcat(filerescve,fileresu);
1.126     brouard  10890:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  10891:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   10892:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  10893:     }
1.227     brouard  10894:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   10895:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  10896: 
1.201     brouard  10897:     strcpy(fileresv,"V_");
                   10898:     strcat(fileresv,fileresu);
1.126     brouard  10899:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   10900:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   10901:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   10902:     }
1.227     brouard  10903:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   10904:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  10905: 
1.145     brouard  10906:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   10907:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   10908:           
1.235   ! brouard  10909:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
        !          10910:     if (cptcovn < 1){i1=1;}
        !          10911:     
        !          10912:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          10913:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
        !          10914:       if(TKresult[nres]!= k)
        !          10915:        continue;
        !          10916:       printf("\n#****** Selected:");
        !          10917:       fprintf(ficrest,"\n#****** Selected:");
        !          10918:       fprintf(ficlog,"\n#****** Selected:");
1.227     brouard  10919:       for(j=1;j<=cptcoveff;j++){ 
                   10920:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10921:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10922:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10923:       }
1.235   ! brouard  10924:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
        !          10925:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          10926:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          10927:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          10928:       }        
1.208     brouard  10929:       fprintf(ficrest,"******\n");
1.227     brouard  10930:       fprintf(ficlog,"******\n");
                   10931:       printf("******\n");
1.208     brouard  10932:       
                   10933:       fprintf(ficresstdeij,"\n#****** ");
                   10934:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  10935:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  10936:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10937:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  10938:       }
1.235   ! brouard  10939:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
        !          10940:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          10941:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          10942:       }        
1.208     brouard  10943:       fprintf(ficresstdeij,"******\n");
                   10944:       fprintf(ficrescveij,"******\n");
                   10945:       
                   10946:       fprintf(ficresvij,"\n#****** ");
1.225     brouard  10947:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  10948:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235   ! brouard  10949:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
        !          10950:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          10951:       }        
1.208     brouard  10952:       fprintf(ficresvij,"******\n");
                   10953:       
                   10954:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10955:       oldm=oldms;savm=savms;
1.235   ! brouard  10956:       printf(" cvevsij ");
        !          10957:       fprintf(ficlog, " cvevsij ");
        !          10958:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  10959:       printf(" end cvevsij \n ");
                   10960:       fprintf(ficlog, " end cvevsij \n ");
                   10961:       
                   10962:       /*
                   10963:        */
                   10964:       /* goto endfree; */
                   10965:       
                   10966:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10967:       pstamp(ficrest);
                   10968:       
                   10969:       
                   10970:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  10971:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   10972:        cptcod= 0; /* To be deleted */
                   10973:        printf("varevsij vpopbased=%d \n",vpopbased);
                   10974:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235   ! brouard  10975:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  10976:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   10977:        if(vpopbased==1)
                   10978:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   10979:        else
                   10980:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   10981:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   10982:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   10983:        fprintf(ficrest,"\n");
                   10984:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   10985:        epj=vector(1,nlstate+1);
                   10986:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   10987:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   10988:        for(age=bage; age <=fage ;age++){
1.235   ! brouard  10989:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  10990:          if (vpopbased==1) {
                   10991:            if(mobilav ==0){
                   10992:              for(i=1; i<=nlstate;i++)
                   10993:                prlim[i][i]=probs[(int)age][i][k];
                   10994:            }else{ /* mobilav */ 
                   10995:              for(i=1; i<=nlstate;i++)
                   10996:                prlim[i][i]=mobaverage[(int)age][i][k];
                   10997:            }
                   10998:          }
1.219     brouard  10999:          
1.227     brouard  11000:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11001:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11002:          /* printf(" age %4.0f ",age); */
                   11003:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11004:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11005:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11006:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11007:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11008:            }
                   11009:            epj[nlstate+1] +=epj[j];
                   11010:          }
                   11011:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11012:          
1.227     brouard  11013:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11014:            for(j=1;j <=nlstate;j++)
                   11015:              vepp += vareij[i][j][(int)age];
                   11016:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11017:          for(j=1;j <=nlstate;j++){
                   11018:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11019:          }
                   11020:          fprintf(ficrest,"\n");
                   11021:        }
1.208     brouard  11022:       } /* End vpopbased */
                   11023:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11024:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11025:       free_vector(epj,1,nlstate+1);
1.235   ! brouard  11026:       printf("done selection\n");fflush(stdout);
        !          11027:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11028:       
1.145     brouard  11029:       /*}*/
1.235   ! brouard  11030:     } /* End k selection */
1.227     brouard  11031: 
                   11032:     printf("done State-specific expectancies\n");fflush(stdout);
                   11033:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11034: 
1.126     brouard  11035:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11036:     
1.201     brouard  11037:     strcpy(fileresvpl,"VPL_");
                   11038:     strcat(fileresvpl,fileresu);
1.126     brouard  11039:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11040:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11041:       exit(0);
                   11042:     }
1.208     brouard  11043:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11044:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11045:     
1.145     brouard  11046:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11047:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11048:     
1.235   ! brouard  11049:     i1=pow(2,cptcoveff);
        !          11050:     if (cptcovn < 1){i1=1;}
        !          11051: 
        !          11052:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          11053:     for(k=1; k<=i1;k++){
        !          11054:       if(TKresult[nres]!= k)
        !          11055:        continue;
1.227     brouard  11056:       fprintf(ficresvpl,"\n#****** ");
                   11057:       printf("\n#****** ");
                   11058:       fprintf(ficlog,"\n#****** ");
                   11059:       for(j=1;j<=cptcoveff;j++) {
                   11060:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11061:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11062:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11063:       }
1.235   ! brouard  11064:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
        !          11065:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          11066:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          11067:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          11068:       }        
1.227     brouard  11069:       fprintf(ficresvpl,"******\n");
                   11070:       printf("******\n");
                   11071:       fprintf(ficlog,"******\n");
                   11072:       
                   11073:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11074:       oldm=oldms;savm=savms;
1.235   ! brouard  11075:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11076:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11077:       /*}*/
1.126     brouard  11078:     }
1.227     brouard  11079:     
1.126     brouard  11080:     fclose(ficresvpl);
1.208     brouard  11081:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11082:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11083:     
                   11084:     free_vector(weight,1,n);
                   11085:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11086:     free_imatrix(s,1,maxwav+1,1,n);
                   11087:     free_matrix(anint,1,maxwav,1,n); 
                   11088:     free_matrix(mint,1,maxwav,1,n);
                   11089:     free_ivector(cod,1,n);
                   11090:     free_ivector(tab,1,NCOVMAX);
                   11091:     fclose(ficresstdeij);
                   11092:     fclose(ficrescveij);
                   11093:     fclose(ficresvij);
                   11094:     fclose(ficrest);
                   11095:     fclose(ficpar);
                   11096:     
                   11097:     
1.126     brouard  11098:     /*---------- End : free ----------------*/
1.219     brouard  11099:     if (mobilav!=0 ||mobilavproj !=0)
                   11100:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11101:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11102:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11103:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11104:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11105:   /* endfree:*/
                   11106:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11107:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11108:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11109:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11110:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11111:   free_matrix(coqvar,1,maxwav,1,n);
                   11112:   free_matrix(covar,0,NCOVMAX,1,n);
                   11113:   free_matrix(matcov,1,npar,1,npar);
                   11114:   free_matrix(hess,1,npar,1,npar);
                   11115:   /*free_vector(delti,1,npar);*/
                   11116:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11117:   free_matrix(agev,1,maxwav,1,imx);
                   11118:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11119:   
                   11120:   free_ivector(ncodemax,1,NCOVMAX);
                   11121:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11122:   free_ivector(Dummy,-1,NCOVMAX);
                   11123:   free_ivector(Fixed,-1,NCOVMAX);
                   11124:   free_ivector(Typevar,-1,NCOVMAX);
                   11125:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11126:   free_ivector(TvarsQ,1,NCOVMAX);
                   11127:   free_ivector(TvarsQind,1,NCOVMAX);
                   11128:   free_ivector(TvarsD,1,NCOVMAX);
                   11129:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11130:   free_ivector(TvarFD,1,NCOVMAX);
                   11131:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11132:   free_ivector(TvarF,1,NCOVMAX);
                   11133:   free_ivector(TvarFind,1,NCOVMAX);
                   11134:   free_ivector(TvarV,1,NCOVMAX);
                   11135:   free_ivector(TvarVind,1,NCOVMAX);
                   11136:   free_ivector(TvarA,1,NCOVMAX);
                   11137:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11138:   free_ivector(TvarFQ,1,NCOVMAX);
                   11139:   free_ivector(TvarFQind,1,NCOVMAX);
                   11140:   free_ivector(TvarVD,1,NCOVMAX);
                   11141:   free_ivector(TvarVDind,1,NCOVMAX);
                   11142:   free_ivector(TvarVQ,1,NCOVMAX);
                   11143:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11144:   free_ivector(Tvarsel,1,NCOVMAX);
                   11145:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11146:   free_ivector(Tposprod,1,NCOVMAX);
                   11147:   free_ivector(Tprod,1,NCOVMAX);
                   11148:   free_ivector(Tvaraff,1,NCOVMAX);
                   11149:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11150:   free_ivector(Tage,1,NCOVMAX);
                   11151:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11152:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11153:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11154:   
                   11155:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11156:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11157:   fflush(fichtm);
                   11158:   fflush(ficgp);
                   11159:   
1.227     brouard  11160:   
1.126     brouard  11161:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11162:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11163:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11164:   }else{
                   11165:     printf("End of Imach\n");
                   11166:     fprintf(ficlog,"End of Imach\n");
                   11167:   }
                   11168:   printf("See log file on %s\n",filelog);
                   11169:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11170:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11171:   rend_time = time(NULL);  
                   11172:   end_time = *localtime(&rend_time);
                   11173:   /* tml = *localtime(&end_time.tm_sec); */
                   11174:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11175:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11176:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11177:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11178:   
1.157     brouard  11179:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11180:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11181:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11182:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11183: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11184:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11185:   fclose(fichtm);
                   11186:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11187:   fclose(fichtmcov);
                   11188:   fclose(ficgp);
                   11189:   fclose(ficlog);
                   11190:   /*------ End -----------*/
1.227     brouard  11191:   
                   11192:   
                   11193:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11194: #ifdef WIN32
1.227     brouard  11195:   if (_chdir(pathcd) != 0)
                   11196:     printf("Can't move to directory %s!\n",path);
                   11197:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11198: #else
1.227     brouard  11199:     if(chdir(pathcd) != 0)
                   11200:       printf("Can't move to directory %s!\n", path);
                   11201:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11202: #endif 
1.126     brouard  11203:     printf("Current directory %s!\n",pathcd);
                   11204:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11205:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11206: #ifdef _WIN32
1.126     brouard  11207:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11208: #endif
                   11209:   if(!stat(plotcmd,&info)){
1.158     brouard  11210:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11211:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11212:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11213:     }else
                   11214:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11215: #ifdef __unix
1.126     brouard  11216:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11217:     if(!stat(plotcmd,&info)){
1.158     brouard  11218:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11219:     }else
                   11220:       strcpy(pplotcmd,plotcmd);
                   11221: #endif
                   11222:   }else
                   11223:     strcpy(pplotcmd,plotcmd);
                   11224:   
                   11225:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11226:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11227:   
1.126     brouard  11228:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11229:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11230:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11231:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11232:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11233:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11234:   }
1.158     brouard  11235:   printf(" Successful, please wait...");
1.126     brouard  11236:   while (z[0] != 'q') {
                   11237:     /* chdir(path); */
1.154     brouard  11238:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11239:     scanf("%s",z);
                   11240: /*     if (z[0] == 'c') system("./imach"); */
                   11241:     if (z[0] == 'e') {
1.158     brouard  11242: #ifdef __APPLE__
1.152     brouard  11243:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11244: #elif __linux
                   11245:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11246: #else
1.152     brouard  11247:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11248: #endif
                   11249:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11250:       system(pplotcmd);
1.126     brouard  11251:     }
                   11252:     else if (z[0] == 'g') system(plotcmd);
                   11253:     else if (z[0] == 'q') exit(0);
                   11254:   }
1.227     brouard  11255: end:
1.126     brouard  11256:   while (z[0] != 'q') {
1.195     brouard  11257:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11258:     scanf("%s",z);
                   11259:   }
                   11260: }

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