Annotation of imach/src/imach.c, revision 1.237

1.237   ! brouard     1: /* $Id: imach.c,v 1.236 2016/08/25 10:50:18 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.237   ! brouard     4:   Revision 1.236  2016/08/25 10:50:18  brouard
        !             5:   *** empty log message ***
        !             6: 
1.236     brouard     7:   Revision 1.235  2016/08/25 06:59:23  brouard
                      8:   *** empty log message ***
                      9: 
1.235     brouard    10:   Revision 1.234  2016/08/23 16:51:20  brouard
                     11:   *** empty log message ***
                     12: 
1.234     brouard    13:   Revision 1.233  2016/08/23 07:40:50  brouard
                     14:   Summary: not working
                     15: 
1.233     brouard    16:   Revision 1.232  2016/08/22 14:20:21  brouard
                     17:   Summary: not working
                     18: 
1.232     brouard    19:   Revision 1.231  2016/08/22 07:17:15  brouard
                     20:   Summary: not working
                     21: 
1.231     brouard    22:   Revision 1.230  2016/08/22 06:55:53  brouard
                     23:   Summary: Not working
                     24: 
1.230     brouard    25:   Revision 1.229  2016/07/23 09:45:53  brouard
                     26:   Summary: Completing for func too
                     27: 
1.229     brouard    28:   Revision 1.228  2016/07/22 17:45:30  brouard
                     29:   Summary: Fixing some arrays, still debugging
                     30: 
1.227     brouard    31:   Revision 1.226  2016/07/12 18:42:34  brouard
                     32:   Summary: temp
                     33: 
1.226     brouard    34:   Revision 1.225  2016/07/12 08:40:03  brouard
                     35:   Summary: saving but not running
                     36: 
1.225     brouard    37:   Revision 1.224  2016/07/01 13:16:01  brouard
                     38:   Summary: Fixes
                     39: 
1.224     brouard    40:   Revision 1.223  2016/02/19 09:23:35  brouard
                     41:   Summary: temporary
                     42: 
1.223     brouard    43:   Revision 1.222  2016/02/17 08:14:50  brouard
                     44:   Summary: Probably last 0.98 stable version 0.98r6
                     45: 
1.222     brouard    46:   Revision 1.221  2016/02/15 23:35:36  brouard
                     47:   Summary: minor bug
                     48: 
1.220     brouard    49:   Revision 1.219  2016/02/15 00:48:12  brouard
                     50:   *** empty log message ***
                     51: 
1.219     brouard    52:   Revision 1.218  2016/02/12 11:29:23  brouard
                     53:   Summary: 0.99 Back projections
                     54: 
1.218     brouard    55:   Revision 1.217  2015/12/23 17:18:31  brouard
                     56:   Summary: Experimental backcast
                     57: 
1.217     brouard    58:   Revision 1.216  2015/12/18 17:32:11  brouard
                     59:   Summary: 0.98r4 Warning and status=-2
                     60: 
                     61:   Version 0.98r4 is now:
                     62:    - displaying an error when status is -1, date of interview unknown and date of death known;
                     63:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                     64:   Older changes concerning s=-2, dating from 2005 have been supersed.
                     65: 
1.216     brouard    66:   Revision 1.215  2015/12/16 08:52:24  brouard
                     67:   Summary: 0.98r4 working
                     68: 
1.215     brouard    69:   Revision 1.214  2015/12/16 06:57:54  brouard
                     70:   Summary: temporary not working
                     71: 
1.214     brouard    72:   Revision 1.213  2015/12/11 18:22:17  brouard
                     73:   Summary: 0.98r4
                     74: 
1.213     brouard    75:   Revision 1.212  2015/11/21 12:47:24  brouard
                     76:   Summary: minor typo
                     77: 
1.212     brouard    78:   Revision 1.211  2015/11/21 12:41:11  brouard
                     79:   Summary: 0.98r3 with some graph of projected cross-sectional
                     80: 
                     81:   Author: Nicolas Brouard
                     82: 
1.211     brouard    83:   Revision 1.210  2015/11/18 17:41:20  brouard
                     84:   Summary: Start working on projected prevalences
                     85: 
1.210     brouard    86:   Revision 1.209  2015/11/17 22:12:03  brouard
                     87:   Summary: Adding ftolpl parameter
                     88:   Author: N Brouard
                     89: 
                     90:   We had difficulties to get smoothed confidence intervals. It was due
                     91:   to the period prevalence which wasn't computed accurately. The inner
                     92:   parameter ftolpl is now an outer parameter of the .imach parameter
                     93:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                     94:   computation are long.
                     95: 
1.209     brouard    96:   Revision 1.208  2015/11/17 14:31:57  brouard
                     97:   Summary: temporary
                     98: 
1.208     brouard    99:   Revision 1.207  2015/10/27 17:36:57  brouard
                    100:   *** empty log message ***
                    101: 
1.207     brouard   102:   Revision 1.206  2015/10/24 07:14:11  brouard
                    103:   *** empty log message ***
                    104: 
1.206     brouard   105:   Revision 1.205  2015/10/23 15:50:53  brouard
                    106:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    107: 
1.205     brouard   108:   Revision 1.204  2015/10/01 16:20:26  brouard
                    109:   Summary: Some new graphs of contribution to likelihood
                    110: 
1.204     brouard   111:   Revision 1.203  2015/09/30 17:45:14  brouard
                    112:   Summary: looking at better estimation of the hessian
                    113: 
                    114:   Also a better criteria for convergence to the period prevalence And
                    115:   therefore adding the number of years needed to converge. (The
                    116:   prevalence in any alive state shold sum to one
                    117: 
1.203     brouard   118:   Revision 1.202  2015/09/22 19:45:16  brouard
                    119:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    120: 
1.202     brouard   121:   Revision 1.201  2015/09/15 17:34:58  brouard
                    122:   Summary: 0.98r0
                    123: 
                    124:   - Some new graphs like suvival functions
                    125:   - Some bugs fixed like model=1+age+V2.
                    126: 
1.201     brouard   127:   Revision 1.200  2015/09/09 16:53:55  brouard
                    128:   Summary: Big bug thanks to Flavia
                    129: 
                    130:   Even model=1+age+V2. did not work anymore
                    131: 
1.200     brouard   132:   Revision 1.199  2015/09/07 14:09:23  brouard
                    133:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    134: 
1.199     brouard   135:   Revision 1.198  2015/09/03 07:14:39  brouard
                    136:   Summary: 0.98q5 Flavia
                    137: 
1.198     brouard   138:   Revision 1.197  2015/09/01 18:24:39  brouard
                    139:   *** empty log message ***
                    140: 
1.197     brouard   141:   Revision 1.196  2015/08/18 23:17:52  brouard
                    142:   Summary: 0.98q5
                    143: 
1.196     brouard   144:   Revision 1.195  2015/08/18 16:28:39  brouard
                    145:   Summary: Adding a hack for testing purpose
                    146: 
                    147:   After reading the title, ftol and model lines, if the comment line has
                    148:   a q, starting with #q, the answer at the end of the run is quit. It
                    149:   permits to run test files in batch with ctest. The former workaround was
                    150:   $ echo q | imach foo.imach
                    151: 
1.195     brouard   152:   Revision 1.194  2015/08/18 13:32:00  brouard
                    153:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    154: 
1.194     brouard   155:   Revision 1.193  2015/08/04 07:17:42  brouard
                    156:   Summary: 0.98q4
                    157: 
1.193     brouard   158:   Revision 1.192  2015/07/16 16:49:02  brouard
                    159:   Summary: Fixing some outputs
                    160: 
1.192     brouard   161:   Revision 1.191  2015/07/14 10:00:33  brouard
                    162:   Summary: Some fixes
                    163: 
1.191     brouard   164:   Revision 1.190  2015/05/05 08:51:13  brouard
                    165:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    166: 
                    167:   Fix 1+age+.
                    168: 
1.190     brouard   169:   Revision 1.189  2015/04/30 14:45:16  brouard
                    170:   Summary: 0.98q2
                    171: 
1.189     brouard   172:   Revision 1.188  2015/04/30 08:27:53  brouard
                    173:   *** empty log message ***
                    174: 
1.188     brouard   175:   Revision 1.187  2015/04/29 09:11:15  brouard
                    176:   *** empty log message ***
                    177: 
1.187     brouard   178:   Revision 1.186  2015/04/23 12:01:52  brouard
                    179:   Summary: V1*age is working now, version 0.98q1
                    180: 
                    181:   Some codes had been disabled in order to simplify and Vn*age was
                    182:   working in the optimization phase, ie, giving correct MLE parameters,
                    183:   but, as usual, outputs were not correct and program core dumped.
                    184: 
1.186     brouard   185:   Revision 1.185  2015/03/11 13:26:42  brouard
                    186:   Summary: Inclusion of compile and links command line for Intel Compiler
                    187: 
1.185     brouard   188:   Revision 1.184  2015/03/11 11:52:39  brouard
                    189:   Summary: Back from Windows 8. Intel Compiler
                    190: 
1.184     brouard   191:   Revision 1.183  2015/03/10 20:34:32  brouard
                    192:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    193: 
                    194:   We use directest instead of original Powell test; probably no
                    195:   incidence on the results, but better justifications;
                    196:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    197:   wrong results.
                    198: 
1.183     brouard   199:   Revision 1.182  2015/02/12 08:19:57  brouard
                    200:   Summary: Trying to keep directest which seems simpler and more general
                    201:   Author: Nicolas Brouard
                    202: 
1.182     brouard   203:   Revision 1.181  2015/02/11 23:22:24  brouard
                    204:   Summary: Comments on Powell added
                    205: 
                    206:   Author:
                    207: 
1.181     brouard   208:   Revision 1.180  2015/02/11 17:33:45  brouard
                    209:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    210: 
1.180     brouard   211:   Revision 1.179  2015/01/04 09:57:06  brouard
                    212:   Summary: back to OS/X
                    213: 
1.179     brouard   214:   Revision 1.178  2015/01/04 09:35:48  brouard
                    215:   *** empty log message ***
                    216: 
1.178     brouard   217:   Revision 1.177  2015/01/03 18:40:56  brouard
                    218:   Summary: Still testing ilc32 on OSX
                    219: 
1.177     brouard   220:   Revision 1.176  2015/01/03 16:45:04  brouard
                    221:   *** empty log message ***
                    222: 
1.176     brouard   223:   Revision 1.175  2015/01/03 16:33:42  brouard
                    224:   *** empty log message ***
                    225: 
1.175     brouard   226:   Revision 1.174  2015/01/03 16:15:49  brouard
                    227:   Summary: Still in cross-compilation
                    228: 
1.174     brouard   229:   Revision 1.173  2015/01/03 12:06:26  brouard
                    230:   Summary: trying to detect cross-compilation
                    231: 
1.173     brouard   232:   Revision 1.172  2014/12/27 12:07:47  brouard
                    233:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    234: 
1.172     brouard   235:   Revision 1.171  2014/12/23 13:26:59  brouard
                    236:   Summary: Back from Visual C
                    237: 
                    238:   Still problem with utsname.h on Windows
                    239: 
1.171     brouard   240:   Revision 1.170  2014/12/23 11:17:12  brouard
                    241:   Summary: Cleaning some \%% back to %%
                    242: 
                    243:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    244: 
1.170     brouard   245:   Revision 1.169  2014/12/22 23:08:31  brouard
                    246:   Summary: 0.98p
                    247: 
                    248:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    249: 
1.169     brouard   250:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   251:   Summary: update
1.169     brouard   252: 
1.168     brouard   253:   Revision 1.167  2014/12/22 13:50:56  brouard
                    254:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    255: 
                    256:   Testing on Linux 64
                    257: 
1.167     brouard   258:   Revision 1.166  2014/12/22 11:40:47  brouard
                    259:   *** empty log message ***
                    260: 
1.166     brouard   261:   Revision 1.165  2014/12/16 11:20:36  brouard
                    262:   Summary: After compiling on Visual C
                    263: 
                    264:   * imach.c (Module): Merging 1.61 to 1.162
                    265: 
1.165     brouard   266:   Revision 1.164  2014/12/16 10:52:11  brouard
                    267:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    268: 
                    269:   * imach.c (Module): Merging 1.61 to 1.162
                    270: 
1.164     brouard   271:   Revision 1.163  2014/12/16 10:30:11  brouard
                    272:   * imach.c (Module): Merging 1.61 to 1.162
                    273: 
1.163     brouard   274:   Revision 1.162  2014/09/25 11:43:39  brouard
                    275:   Summary: temporary backup 0.99!
                    276: 
1.162     brouard   277:   Revision 1.1  2014/09/16 11:06:58  brouard
                    278:   Summary: With some code (wrong) for nlopt
                    279: 
                    280:   Author:
                    281: 
                    282:   Revision 1.161  2014/09/15 20:41:41  brouard
                    283:   Summary: Problem with macro SQR on Intel compiler
                    284: 
1.161     brouard   285:   Revision 1.160  2014/09/02 09:24:05  brouard
                    286:   *** empty log message ***
                    287: 
1.160     brouard   288:   Revision 1.159  2014/09/01 10:34:10  brouard
                    289:   Summary: WIN32
                    290:   Author: Brouard
                    291: 
1.159     brouard   292:   Revision 1.158  2014/08/27 17:11:51  brouard
                    293:   *** empty log message ***
                    294: 
1.158     brouard   295:   Revision 1.157  2014/08/27 16:26:55  brouard
                    296:   Summary: Preparing windows Visual studio version
                    297:   Author: Brouard
                    298: 
                    299:   In order to compile on Visual studio, time.h is now correct and time_t
                    300:   and tm struct should be used. difftime should be used but sometimes I
                    301:   just make the differences in raw time format (time(&now).
                    302:   Trying to suppress #ifdef LINUX
                    303:   Add xdg-open for __linux in order to open default browser.
                    304: 
1.157     brouard   305:   Revision 1.156  2014/08/25 20:10:10  brouard
                    306:   *** empty log message ***
                    307: 
1.156     brouard   308:   Revision 1.155  2014/08/25 18:32:34  brouard
                    309:   Summary: New compile, minor changes
                    310:   Author: Brouard
                    311: 
1.155     brouard   312:   Revision 1.154  2014/06/20 17:32:08  brouard
                    313:   Summary: Outputs now all graphs of convergence to period prevalence
                    314: 
1.154     brouard   315:   Revision 1.153  2014/06/20 16:45:46  brouard
                    316:   Summary: If 3 live state, convergence to period prevalence on same graph
                    317:   Author: Brouard
                    318: 
1.153     brouard   319:   Revision 1.152  2014/06/18 17:54:09  brouard
                    320:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    321: 
1.152     brouard   322:   Revision 1.151  2014/06/18 16:43:30  brouard
                    323:   *** empty log message ***
                    324: 
1.151     brouard   325:   Revision 1.150  2014/06/18 16:42:35  brouard
                    326:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    327:   Author: brouard
                    328: 
1.150     brouard   329:   Revision 1.149  2014/06/18 15:51:14  brouard
                    330:   Summary: Some fixes in parameter files errors
                    331:   Author: Nicolas Brouard
                    332: 
1.149     brouard   333:   Revision 1.148  2014/06/17 17:38:48  brouard
                    334:   Summary: Nothing new
                    335:   Author: Brouard
                    336: 
                    337:   Just a new packaging for OS/X version 0.98nS
                    338: 
1.148     brouard   339:   Revision 1.147  2014/06/16 10:33:11  brouard
                    340:   *** empty log message ***
                    341: 
1.147     brouard   342:   Revision 1.146  2014/06/16 10:20:28  brouard
                    343:   Summary: Merge
                    344:   Author: Brouard
                    345: 
                    346:   Merge, before building revised version.
                    347: 
1.146     brouard   348:   Revision 1.145  2014/06/10 21:23:15  brouard
                    349:   Summary: Debugging with valgrind
                    350:   Author: Nicolas Brouard
                    351: 
                    352:   Lot of changes in order to output the results with some covariates
                    353:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    354:   improve the code.
                    355:   No more memory valgrind error but a lot has to be done in order to
                    356:   continue the work of splitting the code into subroutines.
                    357:   Also, decodemodel has been improved. Tricode is still not
                    358:   optimal. nbcode should be improved. Documentation has been added in
                    359:   the source code.
                    360: 
1.144     brouard   361:   Revision 1.143  2014/01/26 09:45:38  brouard
                    362:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    363: 
                    364:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    365:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    366: 
1.143     brouard   367:   Revision 1.142  2014/01/26 03:57:36  brouard
                    368:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    369: 
                    370:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    371: 
1.142     brouard   372:   Revision 1.141  2014/01/26 02:42:01  brouard
                    373:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    374: 
1.141     brouard   375:   Revision 1.140  2011/09/02 10:37:54  brouard
                    376:   Summary: times.h is ok with mingw32 now.
                    377: 
1.140     brouard   378:   Revision 1.139  2010/06/14 07:50:17  brouard
                    379:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    380:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    381: 
1.139     brouard   382:   Revision 1.138  2010/04/30 18:19:40  brouard
                    383:   *** empty log message ***
                    384: 
1.138     brouard   385:   Revision 1.137  2010/04/29 18:11:38  brouard
                    386:   (Module): Checking covariates for more complex models
                    387:   than V1+V2. A lot of change to be done. Unstable.
                    388: 
1.137     brouard   389:   Revision 1.136  2010/04/26 20:30:53  brouard
                    390:   (Module): merging some libgsl code. Fixing computation
                    391:   of likelione (using inter/intrapolation if mle = 0) in order to
                    392:   get same likelihood as if mle=1.
                    393:   Some cleaning of code and comments added.
                    394: 
1.136     brouard   395:   Revision 1.135  2009/10/29 15:33:14  brouard
                    396:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    397: 
1.135     brouard   398:   Revision 1.134  2009/10/29 13:18:53  brouard
                    399:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    400: 
1.134     brouard   401:   Revision 1.133  2009/07/06 10:21:25  brouard
                    402:   just nforces
                    403: 
1.133     brouard   404:   Revision 1.132  2009/07/06 08:22:05  brouard
                    405:   Many tings
                    406: 
1.132     brouard   407:   Revision 1.131  2009/06/20 16:22:47  brouard
                    408:   Some dimensions resccaled
                    409: 
1.131     brouard   410:   Revision 1.130  2009/05/26 06:44:34  brouard
                    411:   (Module): Max Covariate is now set to 20 instead of 8. A
                    412:   lot of cleaning with variables initialized to 0. Trying to make
                    413:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    414: 
1.130     brouard   415:   Revision 1.129  2007/08/31 13:49:27  lievre
                    416:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    417: 
1.129     lievre    418:   Revision 1.128  2006/06/30 13:02:05  brouard
                    419:   (Module): Clarifications on computing e.j
                    420: 
1.128     brouard   421:   Revision 1.127  2006/04/28 18:11:50  brouard
                    422:   (Module): Yes the sum of survivors was wrong since
                    423:   imach-114 because nhstepm was no more computed in the age
                    424:   loop. Now we define nhstepma in the age loop.
                    425:   (Module): In order to speed up (in case of numerous covariates) we
                    426:   compute health expectancies (without variances) in a first step
                    427:   and then all the health expectancies with variances or standard
                    428:   deviation (needs data from the Hessian matrices) which slows the
                    429:   computation.
                    430:   In the future we should be able to stop the program is only health
                    431:   expectancies and graph are needed without standard deviations.
                    432: 
1.127     brouard   433:   Revision 1.126  2006/04/28 17:23:28  brouard
                    434:   (Module): Yes the sum of survivors was wrong since
                    435:   imach-114 because nhstepm was no more computed in the age
                    436:   loop. Now we define nhstepma in the age loop.
                    437:   Version 0.98h
                    438: 
1.126     brouard   439:   Revision 1.125  2006/04/04 15:20:31  lievre
                    440:   Errors in calculation of health expectancies. Age was not initialized.
                    441:   Forecasting file added.
                    442: 
                    443:   Revision 1.124  2006/03/22 17:13:53  lievre
                    444:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    445:   The log-likelihood is printed in the log file
                    446: 
                    447:   Revision 1.123  2006/03/20 10:52:43  brouard
                    448:   * imach.c (Module): <title> changed, corresponds to .htm file
                    449:   name. <head> headers where missing.
                    450: 
                    451:   * imach.c (Module): Weights can have a decimal point as for
                    452:   English (a comma might work with a correct LC_NUMERIC environment,
                    453:   otherwise the weight is truncated).
                    454:   Modification of warning when the covariates values are not 0 or
                    455:   1.
                    456:   Version 0.98g
                    457: 
                    458:   Revision 1.122  2006/03/20 09:45:41  brouard
                    459:   (Module): Weights can have a decimal point as for
                    460:   English (a comma might work with a correct LC_NUMERIC environment,
                    461:   otherwise the weight is truncated).
                    462:   Modification of warning when the covariates values are not 0 or
                    463:   1.
                    464:   Version 0.98g
                    465: 
                    466:   Revision 1.121  2006/03/16 17:45:01  lievre
                    467:   * imach.c (Module): Comments concerning covariates added
                    468: 
                    469:   * imach.c (Module): refinements in the computation of lli if
                    470:   status=-2 in order to have more reliable computation if stepm is
                    471:   not 1 month. Version 0.98f
                    472: 
                    473:   Revision 1.120  2006/03/16 15:10:38  lievre
                    474:   (Module): refinements in the computation of lli if
                    475:   status=-2 in order to have more reliable computation if stepm is
                    476:   not 1 month. Version 0.98f
                    477: 
                    478:   Revision 1.119  2006/03/15 17:42:26  brouard
                    479:   (Module): Bug if status = -2, the loglikelihood was
                    480:   computed as likelihood omitting the logarithm. Version O.98e
                    481: 
                    482:   Revision 1.118  2006/03/14 18:20:07  brouard
                    483:   (Module): varevsij Comments added explaining the second
                    484:   table of variances if popbased=1 .
                    485:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    486:   (Module): Function pstamp added
                    487:   (Module): Version 0.98d
                    488: 
                    489:   Revision 1.117  2006/03/14 17:16:22  brouard
                    490:   (Module): varevsij Comments added explaining the second
                    491:   table of variances if popbased=1 .
                    492:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    493:   (Module): Function pstamp added
                    494:   (Module): Version 0.98d
                    495: 
                    496:   Revision 1.116  2006/03/06 10:29:27  brouard
                    497:   (Module): Variance-covariance wrong links and
                    498:   varian-covariance of ej. is needed (Saito).
                    499: 
                    500:   Revision 1.115  2006/02/27 12:17:45  brouard
                    501:   (Module): One freematrix added in mlikeli! 0.98c
                    502: 
                    503:   Revision 1.114  2006/02/26 12:57:58  brouard
                    504:   (Module): Some improvements in processing parameter
                    505:   filename with strsep.
                    506: 
                    507:   Revision 1.113  2006/02/24 14:20:24  brouard
                    508:   (Module): Memory leaks checks with valgrind and:
                    509:   datafile was not closed, some imatrix were not freed and on matrix
                    510:   allocation too.
                    511: 
                    512:   Revision 1.112  2006/01/30 09:55:26  brouard
                    513:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    514: 
                    515:   Revision 1.111  2006/01/25 20:38:18  brouard
                    516:   (Module): Lots of cleaning and bugs added (Gompertz)
                    517:   (Module): Comments can be added in data file. Missing date values
                    518:   can be a simple dot '.'.
                    519: 
                    520:   Revision 1.110  2006/01/25 00:51:50  brouard
                    521:   (Module): Lots of cleaning and bugs added (Gompertz)
                    522: 
                    523:   Revision 1.109  2006/01/24 19:37:15  brouard
                    524:   (Module): Comments (lines starting with a #) are allowed in data.
                    525: 
                    526:   Revision 1.108  2006/01/19 18:05:42  lievre
                    527:   Gnuplot problem appeared...
                    528:   To be fixed
                    529: 
                    530:   Revision 1.107  2006/01/19 16:20:37  brouard
                    531:   Test existence of gnuplot in imach path
                    532: 
                    533:   Revision 1.106  2006/01/19 13:24:36  brouard
                    534:   Some cleaning and links added in html output
                    535: 
                    536:   Revision 1.105  2006/01/05 20:23:19  lievre
                    537:   *** empty log message ***
                    538: 
                    539:   Revision 1.104  2005/09/30 16:11:43  lievre
                    540:   (Module): sump fixed, loop imx fixed, and simplifications.
                    541:   (Module): If the status is missing at the last wave but we know
                    542:   that the person is alive, then we can code his/her status as -2
                    543:   (instead of missing=-1 in earlier versions) and his/her
                    544:   contributions to the likelihood is 1 - Prob of dying from last
                    545:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    546:   the healthy state at last known wave). Version is 0.98
                    547: 
                    548:   Revision 1.103  2005/09/30 15:54:49  lievre
                    549:   (Module): sump fixed, loop imx fixed, and simplifications.
                    550: 
                    551:   Revision 1.102  2004/09/15 17:31:30  brouard
                    552:   Add the possibility to read data file including tab characters.
                    553: 
                    554:   Revision 1.101  2004/09/15 10:38:38  brouard
                    555:   Fix on curr_time
                    556: 
                    557:   Revision 1.100  2004/07/12 18:29:06  brouard
                    558:   Add version for Mac OS X. Just define UNIX in Makefile
                    559: 
                    560:   Revision 1.99  2004/06/05 08:57:40  brouard
                    561:   *** empty log message ***
                    562: 
                    563:   Revision 1.98  2004/05/16 15:05:56  brouard
                    564:   New version 0.97 . First attempt to estimate force of mortality
                    565:   directly from the data i.e. without the need of knowing the health
                    566:   state at each age, but using a Gompertz model: log u =a + b*age .
                    567:   This is the basic analysis of mortality and should be done before any
                    568:   other analysis, in order to test if the mortality estimated from the
                    569:   cross-longitudinal survey is different from the mortality estimated
                    570:   from other sources like vital statistic data.
                    571: 
                    572:   The same imach parameter file can be used but the option for mle should be -3.
                    573: 
1.133     brouard   574:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   575:   former routines in order to include the new code within the former code.
                    576: 
                    577:   The output is very simple: only an estimate of the intercept and of
                    578:   the slope with 95% confident intervals.
                    579: 
                    580:   Current limitations:
                    581:   A) Even if you enter covariates, i.e. with the
                    582:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    583:   B) There is no computation of Life Expectancy nor Life Table.
                    584: 
                    585:   Revision 1.97  2004/02/20 13:25:42  lievre
                    586:   Version 0.96d. Population forecasting command line is (temporarily)
                    587:   suppressed.
                    588: 
                    589:   Revision 1.96  2003/07/15 15:38:55  brouard
                    590:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    591:   rewritten within the same printf. Workaround: many printfs.
                    592: 
                    593:   Revision 1.95  2003/07/08 07:54:34  brouard
                    594:   * imach.c (Repository):
                    595:   (Repository): Using imachwizard code to output a more meaningful covariance
                    596:   matrix (cov(a12,c31) instead of numbers.
                    597: 
                    598:   Revision 1.94  2003/06/27 13:00:02  brouard
                    599:   Just cleaning
                    600: 
                    601:   Revision 1.93  2003/06/25 16:33:55  brouard
                    602:   (Module): On windows (cygwin) function asctime_r doesn't
                    603:   exist so I changed back to asctime which exists.
                    604:   (Module): Version 0.96b
                    605: 
                    606:   Revision 1.92  2003/06/25 16:30:45  brouard
                    607:   (Module): On windows (cygwin) function asctime_r doesn't
                    608:   exist so I changed back to asctime which exists.
                    609: 
                    610:   Revision 1.91  2003/06/25 15:30:29  brouard
                    611:   * imach.c (Repository): Duplicated warning errors corrected.
                    612:   (Repository): Elapsed time after each iteration is now output. It
                    613:   helps to forecast when convergence will be reached. Elapsed time
                    614:   is stamped in powell.  We created a new html file for the graphs
                    615:   concerning matrix of covariance. It has extension -cov.htm.
                    616: 
                    617:   Revision 1.90  2003/06/24 12:34:15  brouard
                    618:   (Module): Some bugs corrected for windows. Also, when
                    619:   mle=-1 a template is output in file "or"mypar.txt with the design
                    620:   of the covariance matrix to be input.
                    621: 
                    622:   Revision 1.89  2003/06/24 12:30:52  brouard
                    623:   (Module): Some bugs corrected for windows. Also, when
                    624:   mle=-1 a template is output in file "or"mypar.txt with the design
                    625:   of the covariance matrix to be input.
                    626: 
                    627:   Revision 1.88  2003/06/23 17:54:56  brouard
                    628:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    629: 
                    630:   Revision 1.87  2003/06/18 12:26:01  brouard
                    631:   Version 0.96
                    632: 
                    633:   Revision 1.86  2003/06/17 20:04:08  brouard
                    634:   (Module): Change position of html and gnuplot routines and added
                    635:   routine fileappend.
                    636: 
                    637:   Revision 1.85  2003/06/17 13:12:43  brouard
                    638:   * imach.c (Repository): Check when date of death was earlier that
                    639:   current date of interview. It may happen when the death was just
                    640:   prior to the death. In this case, dh was negative and likelihood
                    641:   was wrong (infinity). We still send an "Error" but patch by
                    642:   assuming that the date of death was just one stepm after the
                    643:   interview.
                    644:   (Repository): Because some people have very long ID (first column)
                    645:   we changed int to long in num[] and we added a new lvector for
                    646:   memory allocation. But we also truncated to 8 characters (left
                    647:   truncation)
                    648:   (Repository): No more line truncation errors.
                    649: 
                    650:   Revision 1.84  2003/06/13 21:44:43  brouard
                    651:   * imach.c (Repository): Replace "freqsummary" at a correct
                    652:   place. It differs from routine "prevalence" which may be called
                    653:   many times. Probs is memory consuming and must be used with
                    654:   parcimony.
                    655:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    656: 
                    657:   Revision 1.83  2003/06/10 13:39:11  lievre
                    658:   *** empty log message ***
                    659: 
                    660:   Revision 1.82  2003/06/05 15:57:20  brouard
                    661:   Add log in  imach.c and  fullversion number is now printed.
                    662: 
                    663: */
                    664: /*
                    665:    Interpolated Markov Chain
                    666: 
                    667:   Short summary of the programme:
                    668:   
1.227     brouard   669:   This program computes Healthy Life Expectancies or State-specific
                    670:   (if states aren't health statuses) Expectancies from
                    671:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    672: 
                    673:   -1- a first survey ("cross") where individuals from different ages
                    674:   are interviewed on their health status or degree of disability (in
                    675:   the case of a health survey which is our main interest)
                    676: 
                    677:   -2- at least a second wave of interviews ("longitudinal") which
                    678:   measure each change (if any) in individual health status.  Health
                    679:   expectancies are computed from the time spent in each health state
                    680:   according to a model. More health states you consider, more time is
                    681:   necessary to reach the Maximum Likelihood of the parameters involved
                    682:   in the model.  The simplest model is the multinomial logistic model
                    683:   where pij is the probability to be observed in state j at the second
                    684:   wave conditional to be observed in state i at the first
                    685:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    686:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    687:   have a more complex model than "constant and age", you should modify
                    688:   the program where the markup *Covariates have to be included here
                    689:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   690:   convergence.
                    691: 
                    692:   The advantage of this computer programme, compared to a simple
                    693:   multinomial logistic model, is clear when the delay between waves is not
                    694:   identical for each individual. Also, if a individual missed an
                    695:   intermediate interview, the information is lost, but taken into
                    696:   account using an interpolation or extrapolation.  
                    697: 
                    698:   hPijx is the probability to be observed in state i at age x+h
                    699:   conditional to the observed state i at age x. The delay 'h' can be
                    700:   split into an exact number (nh*stepm) of unobserved intermediate
                    701:   states. This elementary transition (by month, quarter,
                    702:   semester or year) is modelled as a multinomial logistic.  The hPx
                    703:   matrix is simply the matrix product of nh*stepm elementary matrices
                    704:   and the contribution of each individual to the likelihood is simply
                    705:   hPijx.
                    706: 
                    707:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   708:   of the life expectancies. It also computes the period (stable) prevalence.
                    709: 
                    710: Back prevalence and projections:
1.227     brouard   711: 
                    712:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    713:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    714:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    715:    mobilavproj)
                    716: 
                    717:     Computes the back prevalence limit for any combination of
                    718:     covariate values k at any age between ageminpar and agemaxpar and
                    719:     returns it in **bprlim. In the loops,
                    720: 
                    721:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    722:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    723: 
                    724:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   725:    Computes for any combination of covariates k and any age between bage and fage 
                    726:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    727:                        oldm=oldms;savm=savms;
1.227     brouard   728: 
                    729:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   730:      Computes the transition matrix starting at age 'age' over
                    731:      'nhstepm*hstepm*stepm' months (i.e. until
                    732:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   733:      nhstepm*hstepm matrices. 
                    734: 
                    735:      Returns p3mat[i][j][h] after calling
                    736:      p3mat[i][j][h]=matprod2(newm,
                    737:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    738:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    739:      oldm);
1.226     brouard   740: 
                    741: Important routines
                    742: 
                    743: - func (or funcone), computes logit (pij) distinguishing
                    744:   o fixed variables (single or product dummies or quantitative);
                    745:   o varying variables by:
                    746:    (1) wave (single, product dummies, quantitative), 
                    747:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    748:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    749:        % varying dummy (not done) or quantitative (not done);
                    750: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    751:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    752: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    753:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    754:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   755: 
1.226     brouard   756: 
                    757:   
1.133     brouard   758:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    759:            Institut national d'études démographiques, Paris.
1.126     brouard   760:   This software have been partly granted by Euro-REVES, a concerted action
                    761:   from the European Union.
                    762:   It is copyrighted identically to a GNU software product, ie programme and
                    763:   software can be distributed freely for non commercial use. Latest version
                    764:   can be accessed at http://euroreves.ined.fr/imach .
                    765: 
                    766:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    767:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    768:   
                    769:   **********************************************************************/
                    770: /*
                    771:   main
                    772:   read parameterfile
                    773:   read datafile
                    774:   concatwav
                    775:   freqsummary
                    776:   if (mle >= 1)
                    777:     mlikeli
                    778:   print results files
                    779:   if mle==1 
                    780:      computes hessian
                    781:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    782:       begin-prev-date,...
                    783:   open gnuplot file
                    784:   open html file
1.145     brouard   785:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    786:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    787:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    788:     freexexit2 possible for memory heap.
                    789: 
                    790:   h Pij x                         | pij_nom  ficrestpij
                    791:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    792:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    793:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    794: 
                    795:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    796:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    797:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    798:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    799:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    800: 
1.126     brouard   801:   forecasting if prevfcast==1 prevforecast call prevalence()
                    802:   health expectancies
                    803:   Variance-covariance of DFLE
                    804:   prevalence()
                    805:    movingaverage()
                    806:   varevsij() 
                    807:   if popbased==1 varevsij(,popbased)
                    808:   total life expectancies
                    809:   Variance of period (stable) prevalence
                    810:  end
                    811: */
                    812: 
1.187     brouard   813: /* #define DEBUG */
                    814: /* #define DEBUGBRENT */
1.203     brouard   815: /* #define DEBUGLINMIN */
                    816: /* #define DEBUGHESS */
                    817: #define DEBUGHESSIJ
1.224     brouard   818: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   819: #define POWELL /* Instead of NLOPT */
1.224     brouard   820: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   821: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    822: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   823: 
                    824: #include <math.h>
                    825: #include <stdio.h>
                    826: #include <stdlib.h>
                    827: #include <string.h>
1.226     brouard   828: #include <ctype.h>
1.159     brouard   829: 
                    830: #ifdef _WIN32
                    831: #include <io.h>
1.172     brouard   832: #include <windows.h>
                    833: #include <tchar.h>
1.159     brouard   834: #else
1.126     brouard   835: #include <unistd.h>
1.159     brouard   836: #endif
1.126     brouard   837: 
                    838: #include <limits.h>
                    839: #include <sys/types.h>
1.171     brouard   840: 
                    841: #if defined(__GNUC__)
                    842: #include <sys/utsname.h> /* Doesn't work on Windows */
                    843: #endif
                    844: 
1.126     brouard   845: #include <sys/stat.h>
                    846: #include <errno.h>
1.159     brouard   847: /* extern int errno; */
1.126     brouard   848: 
1.157     brouard   849: /* #ifdef LINUX */
                    850: /* #include <time.h> */
                    851: /* #include "timeval.h" */
                    852: /* #else */
                    853: /* #include <sys/time.h> */
                    854: /* #endif */
                    855: 
1.126     brouard   856: #include <time.h>
                    857: 
1.136     brouard   858: #ifdef GSL
                    859: #include <gsl/gsl_errno.h>
                    860: #include <gsl/gsl_multimin.h>
                    861: #endif
                    862: 
1.167     brouard   863: 
1.162     brouard   864: #ifdef NLOPT
                    865: #include <nlopt.h>
                    866: typedef struct {
                    867:   double (* function)(double [] );
                    868: } myfunc_data ;
                    869: #endif
                    870: 
1.126     brouard   871: /* #include <libintl.h> */
                    872: /* #define _(String) gettext (String) */
                    873: 
1.141     brouard   874: #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   875: 
                    876: #define GNUPLOTPROGRAM "gnuplot"
                    877: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    878: #define FILENAMELENGTH 132
                    879: 
                    880: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    881: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    882: 
1.144     brouard   883: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    884: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   885: 
                    886: #define NINTERVMAX 8
1.144     brouard   887: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    888: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    889: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   890: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   891: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    892: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   893: #define MAXN 20000
1.144     brouard   894: #define YEARM 12. /**< Number of months per year */
1.218     brouard   895: /* #define AGESUP 130 */
                    896: #define AGESUP 150
                    897: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   898: #define AGEBASE 40
1.194     brouard   899: #define AGEOVERFLOW 1.e20
1.164     brouard   900: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   901: #ifdef _WIN32
                    902: #define DIRSEPARATOR '\\'
                    903: #define CHARSEPARATOR "\\"
                    904: #define ODIRSEPARATOR '/'
                    905: #else
1.126     brouard   906: #define DIRSEPARATOR '/'
                    907: #define CHARSEPARATOR "/"
                    908: #define ODIRSEPARATOR '\\'
                    909: #endif
                    910: 
1.237   ! brouard   911: /* $Id: imach.c,v 1.236 2016/08/25 10:50:18 brouard Exp $ */
1.126     brouard   912: /* $State: Exp $ */
1.196     brouard   913: #include "version.h"
                    914: char version[]=__IMACH_VERSION__;
1.224     brouard   915: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.237   ! brouard   916: char fullversion[]="$Revision: 1.236 $ $Date: 2016/08/25 10:50:18 $"; 
1.126     brouard   917: char strstart[80];
                    918: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   919: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   920: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   921: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    922: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    923: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   924: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    925: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   926: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    927: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    928: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   929: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    930: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   931: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   932: int nsd=0; /**< Total number of single dummy variables (output) */
                    933: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   934: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   935: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   936: int ntveff=0; /**< ntveff number of effective time varying variables */
                    937: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard   938: int cptcov=0; /* Working variable */
1.218     brouard   939: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard   940: int npar=NPARMAX;
                    941: int nlstate=2; /* Number of live states */
                    942: int ndeath=1; /* Number of dead states */
1.130     brouard   943: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard   944: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard   945: int popbased=0;
                    946: 
                    947: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard   948: int maxwav=0; /* Maxim number of waves */
                    949: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                    950: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                    951: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard   952:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard   953: int mle=1, weightopt=0;
1.126     brouard   954: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                    955: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                    956: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                    957:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard   958: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard   959: int selected(int kvar); /* Is covariate kvar selected for printing results */
                    960: 
1.130     brouard   961: double jmean=1; /* Mean space between 2 waves */
1.145     brouard   962: double **matprod2(); /* test */
1.126     brouard   963: double **oldm, **newm, **savm; /* Working pointers to matrices */
                    964: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard   965: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                    966: 
1.136     brouard   967: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard   968: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard   969: FILE *ficlog, *ficrespow;
1.130     brouard   970: int globpr=0; /* Global variable for printing or not */
1.126     brouard   971: double fretone; /* Only one call to likelihood */
1.130     brouard   972: long ipmx=0; /* Number of contributions */
1.126     brouard   973: double sw; /* Sum of weights */
                    974: char filerespow[FILENAMELENGTH];
                    975: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                    976: FILE *ficresilk;
                    977: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                    978: FILE *ficresprobmorprev;
                    979: FILE *fichtm, *fichtmcov; /* Html File */
                    980: FILE *ficreseij;
                    981: char filerese[FILENAMELENGTH];
                    982: FILE *ficresstdeij;
                    983: char fileresstde[FILENAMELENGTH];
                    984: FILE *ficrescveij;
                    985: char filerescve[FILENAMELENGTH];
                    986: FILE  *ficresvij;
                    987: char fileresv[FILENAMELENGTH];
                    988: FILE  *ficresvpl;
                    989: char fileresvpl[FILENAMELENGTH];
                    990: char title[MAXLINE];
1.234     brouard   991: char model[MAXLINE]; /**< The model line */
1.217     brouard   992: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard   993: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                    994: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                    995: char command[FILENAMELENGTH];
                    996: int  outcmd=0;
                    997: 
1.217     brouard   998: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard   999: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1000: char filelog[FILENAMELENGTH]; /* Log file */
                   1001: char filerest[FILENAMELENGTH];
                   1002: char fileregp[FILENAMELENGTH];
                   1003: char popfile[FILENAMELENGTH];
                   1004: 
                   1005: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1006: 
1.157     brouard  1007: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1008: /* struct timezone tzp; */
                   1009: /* extern int gettimeofday(); */
                   1010: struct tm tml, *gmtime(), *localtime();
                   1011: 
                   1012: extern time_t time();
                   1013: 
                   1014: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1015: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1016: struct tm tm;
                   1017: 
1.126     brouard  1018: char strcurr[80], strfor[80];
                   1019: 
                   1020: char *endptr;
                   1021: long lval;
                   1022: double dval;
                   1023: 
                   1024: #define NR_END 1
                   1025: #define FREE_ARG char*
                   1026: #define FTOL 1.0e-10
                   1027: 
                   1028: #define NRANSI 
                   1029: #define ITMAX 200 
                   1030: 
                   1031: #define TOL 2.0e-4 
                   1032: 
                   1033: #define CGOLD 0.3819660 
                   1034: #define ZEPS 1.0e-10 
                   1035: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1036: 
                   1037: #define GOLD 1.618034 
                   1038: #define GLIMIT 100.0 
                   1039: #define TINY 1.0e-20 
                   1040: 
                   1041: static double maxarg1,maxarg2;
                   1042: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1043: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1044:   
                   1045: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1046: #define rint(a) floor(a+0.5)
1.166     brouard  1047: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1048: #define mytinydouble 1.0e-16
1.166     brouard  1049: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1050: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1051: /* static double dsqrarg; */
                   1052: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1053: static double sqrarg;
                   1054: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1055: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1056: int agegomp= AGEGOMP;
                   1057: 
                   1058: int imx; 
                   1059: int stepm=1;
                   1060: /* Stepm, step in month: minimum step interpolation*/
                   1061: 
                   1062: int estepm;
                   1063: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1064: 
                   1065: int m,nb;
                   1066: long *num;
1.197     brouard  1067: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1068: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1069:                   covariate for which somebody answered excluding 
                   1070:                   undefined. Usually 2: 0 and 1. */
                   1071: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1072:                             covariate for which somebody answered including 
                   1073:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1074: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1075: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1076: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1077: double *ageexmed,*agecens;
                   1078: double dateintmean=0;
                   1079: 
                   1080: double *weight;
                   1081: int **s; /* Status */
1.141     brouard  1082: double *agedc;
1.145     brouard  1083: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1084:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1085:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1086: double **coqvar; /* Fixed quantitative covariate iqv */
                   1087: double ***cotvar; /* Time varying covariate itv */
                   1088: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1089: double  idx; 
                   1090: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1091: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1092: /*k          1  2   3   4     5    6    7     8    9 */
                   1093: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1094: /* Tndvar[k]    1   2   3               4          5 */
                   1095: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1096: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1097: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1098: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1099: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1100: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1101: /* Tprod[i]=k           4               7            */
                   1102: /* Tage[i]=k                  5               8      */
                   1103: /* */
                   1104: /* Type                    */
                   1105: /* V         1  2  3  4  5 */
                   1106: /*           F  F  V  V  V */
                   1107: /*           D  Q  D  D  Q */
                   1108: /*                         */
                   1109: int *TvarsD;
                   1110: int *TvarsDind;
                   1111: int *TvarsQ;
                   1112: int *TvarsQind;
                   1113: 
1.235     brouard  1114: #define MAXRESULTLINES 10
                   1115: int nresult=0;
                   1116: int TKresult[MAXRESULTLINES];
1.237   ! brouard  1117: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
        !          1118: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1119: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1120: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237   ! brouard  1121: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1122: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1123: 
1.234     brouard  1124: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1125: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1126: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1127: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1128: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1129: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1130: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1131: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1132: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1133: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1134: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1135: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1136: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1137: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1138: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1139: 
1.230     brouard  1140: int *Tvarsel; /**< Selected covariates for output */
                   1141: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1142: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1143: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1144: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.197     brouard  1145: int *Tage;
1.227     brouard  1146: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1147: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1148: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1149: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1150: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1151: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1152: int **Tvard;
                   1153: int *Tprod;/**< Gives the k position of the k1 product */
                   1154: int *Tposprod; /**< Gives the k1 product from the k position */
                   1155: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   1156:    if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
                   1157:    Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
                   1158: */
                   1159: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1160: double *lsurv, *lpop, *tpop;
                   1161: 
1.231     brouard  1162: #define FD 1; /* Fixed dummy covariate */
                   1163: #define FQ 2; /* Fixed quantitative covariate */
                   1164: #define FP 3; /* Fixed product covariate */
                   1165: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1166: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1167: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1168: #define VD 10; /* Varying dummy covariate */
                   1169: #define VQ 11; /* Varying quantitative covariate */
                   1170: #define VP 12; /* Varying product covariate */
                   1171: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1172: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1173: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1174: #define APFD 16; /* Age product * fixed dummy covariate */
                   1175: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1176: #define APVD 18; /* Age product * varying dummy covariate */
                   1177: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1178: 
                   1179: #define FTYPE 1; /* Fixed covariate */
                   1180: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1181: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1182: 
                   1183: struct kmodel{
                   1184:        int maintype; /* main type */
                   1185:        int subtype; /* subtype */
                   1186: };
                   1187: struct kmodel modell[NCOVMAX];
                   1188: 
1.143     brouard  1189: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1190: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1191: 
                   1192: /**************** split *************************/
                   1193: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1194: {
                   1195:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1196:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1197:   */ 
                   1198:   char *ss;                            /* pointer */
1.186     brouard  1199:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1200: 
                   1201:   l1 = strlen(path );                  /* length of path */
                   1202:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1203:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1204:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1205:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1206:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1207:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1208:     /* get current working directory */
                   1209:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1210: #ifdef WIN32
                   1211:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1212: #else
                   1213:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1214: #endif
1.126     brouard  1215:       return( GLOCK_ERROR_GETCWD );
                   1216:     }
                   1217:     /* got dirc from getcwd*/
                   1218:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1219:   } else {                             /* strip directory from path */
1.126     brouard  1220:     ss++;                              /* after this, the filename */
                   1221:     l2 = strlen( ss );                 /* length of filename */
                   1222:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1223:     strcpy( name, ss );                /* save file name */
                   1224:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1225:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1226:     printf(" DIRC2 = %s \n",dirc);
                   1227:   }
                   1228:   /* We add a separator at the end of dirc if not exists */
                   1229:   l1 = strlen( dirc );                 /* length of directory */
                   1230:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1231:     dirc[l1] =  DIRSEPARATOR;
                   1232:     dirc[l1+1] = 0; 
                   1233:     printf(" DIRC3 = %s \n",dirc);
                   1234:   }
                   1235:   ss = strrchr( name, '.' );           /* find last / */
                   1236:   if (ss >0){
                   1237:     ss++;
                   1238:     strcpy(ext,ss);                    /* save extension */
                   1239:     l1= strlen( name);
                   1240:     l2= strlen(ss)+1;
                   1241:     strncpy( finame, name, l1-l2);
                   1242:     finame[l1-l2]= 0;
                   1243:   }
                   1244: 
                   1245:   return( 0 );                         /* we're done */
                   1246: }
                   1247: 
                   1248: 
                   1249: /******************************************/
                   1250: 
                   1251: void replace_back_to_slash(char *s, char*t)
                   1252: {
                   1253:   int i;
                   1254:   int lg=0;
                   1255:   i=0;
                   1256:   lg=strlen(t);
                   1257:   for(i=0; i<= lg; i++) {
                   1258:     (s[i] = t[i]);
                   1259:     if (t[i]== '\\') s[i]='/';
                   1260:   }
                   1261: }
                   1262: 
1.132     brouard  1263: char *trimbb(char *out, char *in)
1.137     brouard  1264: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1265:   char *s;
                   1266:   s=out;
                   1267:   while (*in != '\0'){
1.137     brouard  1268:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1269:       in++;
                   1270:     }
                   1271:     *out++ = *in++;
                   1272:   }
                   1273:   *out='\0';
                   1274:   return s;
                   1275: }
                   1276: 
1.187     brouard  1277: /* char *substrchaine(char *out, char *in, char *chain) */
                   1278: /* { */
                   1279: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1280: /*   char *s, *t; */
                   1281: /*   t=in;s=out; */
                   1282: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1283: /*     *out++ = *in++; */
                   1284: /*   } */
                   1285: 
                   1286: /*   /\* *in matches *chain *\/ */
                   1287: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1288: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1289: /*   } */
                   1290: /*   in--; chain--; */
                   1291: /*   while ( (*in != '\0')){ */
                   1292: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1293: /*     *out++ = *in++; */
                   1294: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1295: /*   } */
                   1296: /*   *out='\0'; */
                   1297: /*   out=s; */
                   1298: /*   return out; */
                   1299: /* } */
                   1300: char *substrchaine(char *out, char *in, char *chain)
                   1301: {
                   1302:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1303:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1304: 
                   1305:   char *strloc;
                   1306: 
                   1307:   strcpy (out, in); 
                   1308:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1309:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1310:   if(strloc != NULL){ 
                   1311:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1312:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1313:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1314:   }
                   1315:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1316:   return out;
                   1317: }
                   1318: 
                   1319: 
1.145     brouard  1320: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1321: {
1.187     brouard  1322:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1323:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1324:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1325:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1326:   */
1.160     brouard  1327:   char *s, *t;
1.145     brouard  1328:   t=in;s=in;
                   1329:   while ((*in != occ) && (*in != '\0')){
                   1330:     *alocc++ = *in++;
                   1331:   }
                   1332:   if( *in == occ){
                   1333:     *(alocc)='\0';
                   1334:     s=++in;
                   1335:   }
                   1336:  
                   1337:   if (s == t) {/* occ not found */
                   1338:     *(alocc-(in-s))='\0';
                   1339:     in=s;
                   1340:   }
                   1341:   while ( *in != '\0'){
                   1342:     *blocc++ = *in++;
                   1343:   }
                   1344: 
                   1345:   *blocc='\0';
                   1346:   return t;
                   1347: }
1.137     brouard  1348: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1349: {
1.187     brouard  1350:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1351:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1352:      gives blocc="abcdef2ghi" and alocc="j".
                   1353:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1354:   */
                   1355:   char *s, *t;
                   1356:   t=in;s=in;
                   1357:   while (*in != '\0'){
                   1358:     while( *in == occ){
                   1359:       *blocc++ = *in++;
                   1360:       s=in;
                   1361:     }
                   1362:     *blocc++ = *in++;
                   1363:   }
                   1364:   if (s == t) /* occ not found */
                   1365:     *(blocc-(in-s))='\0';
                   1366:   else
                   1367:     *(blocc-(in-s)-1)='\0';
                   1368:   in=s;
                   1369:   while ( *in != '\0'){
                   1370:     *alocc++ = *in++;
                   1371:   }
                   1372: 
                   1373:   *alocc='\0';
                   1374:   return s;
                   1375: }
                   1376: 
1.126     brouard  1377: int nbocc(char *s, char occ)
                   1378: {
                   1379:   int i,j=0;
                   1380:   int lg=20;
                   1381:   i=0;
                   1382:   lg=strlen(s);
                   1383:   for(i=0; i<= lg; i++) {
1.234     brouard  1384:     if  (s[i] == occ ) j++;
1.126     brouard  1385:   }
                   1386:   return j;
                   1387: }
                   1388: 
1.137     brouard  1389: /* void cutv(char *u,char *v, char*t, char occ) */
                   1390: /* { */
                   1391: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1392: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1393: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1394: /*   int i,lg,j,p=0; */
                   1395: /*   i=0; */
                   1396: /*   lg=strlen(t); */
                   1397: /*   for(j=0; j<=lg-1; j++) { */
                   1398: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1399: /*   } */
1.126     brouard  1400: 
1.137     brouard  1401: /*   for(j=0; j<p; j++) { */
                   1402: /*     (u[j] = t[j]); */
                   1403: /*   } */
                   1404: /*      u[p]='\0'; */
1.126     brouard  1405: 
1.137     brouard  1406: /*    for(j=0; j<= lg; j++) { */
                   1407: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1408: /*   } */
                   1409: /* } */
1.126     brouard  1410: 
1.160     brouard  1411: #ifdef _WIN32
                   1412: char * strsep(char **pp, const char *delim)
                   1413: {
                   1414:   char *p, *q;
                   1415:          
                   1416:   if ((p = *pp) == NULL)
                   1417:     return 0;
                   1418:   if ((q = strpbrk (p, delim)) != NULL)
                   1419:   {
                   1420:     *pp = q + 1;
                   1421:     *q = '\0';
                   1422:   }
                   1423:   else
                   1424:     *pp = 0;
                   1425:   return p;
                   1426: }
                   1427: #endif
                   1428: 
1.126     brouard  1429: /********************** nrerror ********************/
                   1430: 
                   1431: void nrerror(char error_text[])
                   1432: {
                   1433:   fprintf(stderr,"ERREUR ...\n");
                   1434:   fprintf(stderr,"%s\n",error_text);
                   1435:   exit(EXIT_FAILURE);
                   1436: }
                   1437: /*********************** vector *******************/
                   1438: double *vector(int nl, int nh)
                   1439: {
                   1440:   double *v;
                   1441:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1442:   if (!v) nrerror("allocation failure in vector");
                   1443:   return v-nl+NR_END;
                   1444: }
                   1445: 
                   1446: /************************ free vector ******************/
                   1447: void free_vector(double*v, int nl, int nh)
                   1448: {
                   1449:   free((FREE_ARG)(v+nl-NR_END));
                   1450: }
                   1451: 
                   1452: /************************ivector *******************************/
                   1453: int *ivector(long nl,long nh)
                   1454: {
                   1455:   int *v;
                   1456:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1457:   if (!v) nrerror("allocation failure in ivector");
                   1458:   return v-nl+NR_END;
                   1459: }
                   1460: 
                   1461: /******************free ivector **************************/
                   1462: void free_ivector(int *v, long nl, long nh)
                   1463: {
                   1464:   free((FREE_ARG)(v+nl-NR_END));
                   1465: }
                   1466: 
                   1467: /************************lvector *******************************/
                   1468: long *lvector(long nl,long nh)
                   1469: {
                   1470:   long *v;
                   1471:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1472:   if (!v) nrerror("allocation failure in ivector");
                   1473:   return v-nl+NR_END;
                   1474: }
                   1475: 
                   1476: /******************free lvector **************************/
                   1477: void free_lvector(long *v, long nl, long nh)
                   1478: {
                   1479:   free((FREE_ARG)(v+nl-NR_END));
                   1480: }
                   1481: 
                   1482: /******************* imatrix *******************************/
                   1483: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1484:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1485: { 
                   1486:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1487:   int **m; 
                   1488:   
                   1489:   /* allocate pointers to rows */ 
                   1490:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1491:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1492:   m += NR_END; 
                   1493:   m -= nrl; 
                   1494:   
                   1495:   
                   1496:   /* allocate rows and set pointers to them */ 
                   1497:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1498:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1499:   m[nrl] += NR_END; 
                   1500:   m[nrl] -= ncl; 
                   1501:   
                   1502:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1503:   
                   1504:   /* return pointer to array of pointers to rows */ 
                   1505:   return m; 
                   1506: } 
                   1507: 
                   1508: /****************** free_imatrix *************************/
                   1509: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1510:       int **m;
                   1511:       long nch,ncl,nrh,nrl; 
                   1512:      /* free an int matrix allocated by imatrix() */ 
                   1513: { 
                   1514:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1515:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1516: } 
                   1517: 
                   1518: /******************* matrix *******************************/
                   1519: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1520: {
                   1521:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1522:   double **m;
                   1523: 
                   1524:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1525:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1526:   m += NR_END;
                   1527:   m -= nrl;
                   1528: 
                   1529:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1530:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1531:   m[nrl] += NR_END;
                   1532:   m[nrl] -= ncl;
                   1533: 
                   1534:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1535:   return m;
1.145     brouard  1536:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1537: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1538: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1539:    */
                   1540: }
                   1541: 
                   1542: /*************************free matrix ************************/
                   1543: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1544: {
                   1545:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1546:   free((FREE_ARG)(m+nrl-NR_END));
                   1547: }
                   1548: 
                   1549: /******************* ma3x *******************************/
                   1550: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1551: {
                   1552:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1553:   double ***m;
                   1554: 
                   1555:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1556:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1557:   m += NR_END;
                   1558:   m -= nrl;
                   1559: 
                   1560:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1561:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1562:   m[nrl] += NR_END;
                   1563:   m[nrl] -= ncl;
                   1564: 
                   1565:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1566: 
                   1567:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1568:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1569:   m[nrl][ncl] += NR_END;
                   1570:   m[nrl][ncl] -= nll;
                   1571:   for (j=ncl+1; j<=nch; j++) 
                   1572:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1573:   
                   1574:   for (i=nrl+1; i<=nrh; i++) {
                   1575:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1576:     for (j=ncl+1; j<=nch; j++) 
                   1577:       m[i][j]=m[i][j-1]+nlay;
                   1578:   }
                   1579:   return m; 
                   1580:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1581:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1582:   */
                   1583: }
                   1584: 
                   1585: /*************************free ma3x ************************/
                   1586: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1587: {
                   1588:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1589:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1590:   free((FREE_ARG)(m+nrl-NR_END));
                   1591: }
                   1592: 
                   1593: /*************** function subdirf ***********/
                   1594: char *subdirf(char fileres[])
                   1595: {
                   1596:   /* Caution optionfilefiname is hidden */
                   1597:   strcpy(tmpout,optionfilefiname);
                   1598:   strcat(tmpout,"/"); /* Add to the right */
                   1599:   strcat(tmpout,fileres);
                   1600:   return tmpout;
                   1601: }
                   1602: 
                   1603: /*************** function subdirf2 ***********/
                   1604: char *subdirf2(char fileres[], char *preop)
                   1605: {
                   1606:   
                   1607:   /* Caution optionfilefiname is hidden */
                   1608:   strcpy(tmpout,optionfilefiname);
                   1609:   strcat(tmpout,"/");
                   1610:   strcat(tmpout,preop);
                   1611:   strcat(tmpout,fileres);
                   1612:   return tmpout;
                   1613: }
                   1614: 
                   1615: /*************** function subdirf3 ***********/
                   1616: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1617: {
                   1618:   
                   1619:   /* Caution optionfilefiname is hidden */
                   1620:   strcpy(tmpout,optionfilefiname);
                   1621:   strcat(tmpout,"/");
                   1622:   strcat(tmpout,preop);
                   1623:   strcat(tmpout,preop2);
                   1624:   strcat(tmpout,fileres);
                   1625:   return tmpout;
                   1626: }
1.213     brouard  1627:  
                   1628: /*************** function subdirfext ***********/
                   1629: char *subdirfext(char fileres[], char *preop, char *postop)
                   1630: {
                   1631:   
                   1632:   strcpy(tmpout,preop);
                   1633:   strcat(tmpout,fileres);
                   1634:   strcat(tmpout,postop);
                   1635:   return tmpout;
                   1636: }
1.126     brouard  1637: 
1.213     brouard  1638: /*************** function subdirfext3 ***********/
                   1639: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1640: {
                   1641:   
                   1642:   /* Caution optionfilefiname is hidden */
                   1643:   strcpy(tmpout,optionfilefiname);
                   1644:   strcat(tmpout,"/");
                   1645:   strcat(tmpout,preop);
                   1646:   strcat(tmpout,fileres);
                   1647:   strcat(tmpout,postop);
                   1648:   return tmpout;
                   1649: }
                   1650:  
1.162     brouard  1651: char *asc_diff_time(long time_sec, char ascdiff[])
                   1652: {
                   1653:   long sec_left, days, hours, minutes;
                   1654:   days = (time_sec) / (60*60*24);
                   1655:   sec_left = (time_sec) % (60*60*24);
                   1656:   hours = (sec_left) / (60*60) ;
                   1657:   sec_left = (sec_left) %(60*60);
                   1658:   minutes = (sec_left) /60;
                   1659:   sec_left = (sec_left) % (60);
                   1660:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1661:   return ascdiff;
                   1662: }
                   1663: 
1.126     brouard  1664: /***************** f1dim *************************/
                   1665: extern int ncom; 
                   1666: extern double *pcom,*xicom;
                   1667: extern double (*nrfunc)(double []); 
                   1668:  
                   1669: double f1dim(double x) 
                   1670: { 
                   1671:   int j; 
                   1672:   double f;
                   1673:   double *xt; 
                   1674:  
                   1675:   xt=vector(1,ncom); 
                   1676:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1677:   f=(*nrfunc)(xt); 
                   1678:   free_vector(xt,1,ncom); 
                   1679:   return f; 
                   1680: } 
                   1681: 
                   1682: /*****************brent *************************/
                   1683: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1684: {
                   1685:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1686:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1687:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1688:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1689:    * returned function value. 
                   1690:   */
1.126     brouard  1691:   int iter; 
                   1692:   double a,b,d,etemp;
1.159     brouard  1693:   double fu=0,fv,fw,fx;
1.164     brouard  1694:   double ftemp=0.;
1.126     brouard  1695:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1696:   double e=0.0; 
                   1697:  
                   1698:   a=(ax < cx ? ax : cx); 
                   1699:   b=(ax > cx ? ax : cx); 
                   1700:   x=w=v=bx; 
                   1701:   fw=fv=fx=(*f)(x); 
                   1702:   for (iter=1;iter<=ITMAX;iter++) { 
                   1703:     xm=0.5*(a+b); 
                   1704:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1705:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1706:     printf(".");fflush(stdout);
                   1707:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1708: #ifdef DEBUGBRENT
1.126     brouard  1709:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1710:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1711:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1712: #endif
                   1713:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1714:       *xmin=x; 
                   1715:       return fx; 
                   1716:     } 
                   1717:     ftemp=fu;
                   1718:     if (fabs(e) > tol1) { 
                   1719:       r=(x-w)*(fx-fv); 
                   1720:       q=(x-v)*(fx-fw); 
                   1721:       p=(x-v)*q-(x-w)*r; 
                   1722:       q=2.0*(q-r); 
                   1723:       if (q > 0.0) p = -p; 
                   1724:       q=fabs(q); 
                   1725:       etemp=e; 
                   1726:       e=d; 
                   1727:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1728:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1729:       else { 
1.224     brouard  1730:                                d=p/q; 
                   1731:                                u=x+d; 
                   1732:                                if (u-a < tol2 || b-u < tol2) 
                   1733:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1734:       } 
                   1735:     } else { 
                   1736:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1737:     } 
                   1738:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1739:     fu=(*f)(u); 
                   1740:     if (fu <= fx) { 
                   1741:       if (u >= x) a=x; else b=x; 
                   1742:       SHFT(v,w,x,u) 
1.183     brouard  1743:       SHFT(fv,fw,fx,fu) 
                   1744:     } else { 
                   1745:       if (u < x) a=u; else b=u; 
                   1746:       if (fu <= fw || w == x) { 
1.224     brouard  1747:                                v=w; 
                   1748:                                w=u; 
                   1749:                                fv=fw; 
                   1750:                                fw=fu; 
1.183     brouard  1751:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1752:                                v=u; 
                   1753:                                fv=fu; 
1.183     brouard  1754:       } 
                   1755:     } 
1.126     brouard  1756:   } 
                   1757:   nrerror("Too many iterations in brent"); 
                   1758:   *xmin=x; 
                   1759:   return fx; 
                   1760: } 
                   1761: 
                   1762: /****************** mnbrak ***********************/
                   1763: 
                   1764: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1765:            double (*func)(double)) 
1.183     brouard  1766: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1767: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1768: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1769: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1770:    */
1.126     brouard  1771:   double ulim,u,r,q, dum;
                   1772:   double fu; 
1.187     brouard  1773: 
                   1774:   double scale=10.;
                   1775:   int iterscale=0;
                   1776: 
                   1777:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1778:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1779: 
                   1780: 
                   1781:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1782:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1783:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1784:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1785:   /* } */
                   1786: 
1.126     brouard  1787:   if (*fb > *fa) { 
                   1788:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1789:     SHFT(dum,*fb,*fa,dum) 
                   1790:   } 
1.126     brouard  1791:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1792:   *fc=(*func)(*cx); 
1.183     brouard  1793: #ifdef DEBUG
1.224     brouard  1794:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1795:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1796: #endif
1.224     brouard  1797:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1798:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1799:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1800:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1801:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1802:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1803:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1804:       fu=(*func)(u); 
1.163     brouard  1805: #ifdef DEBUG
                   1806:       /* f(x)=A(x-u)**2+f(u) */
                   1807:       double A, fparabu; 
                   1808:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1809:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1810:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1811:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1812:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1813:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1814:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1815:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1816: #endif 
1.184     brouard  1817: #ifdef MNBRAKORIGINAL
1.183     brouard  1818: #else
1.191     brouard  1819: /*       if (fu > *fc) { */
                   1820: /* #ifdef DEBUG */
                   1821: /*       printf("mnbrak4  fu > fc \n"); */
                   1822: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1823: /* #endif */
                   1824: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1825: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1826: /*     dum=u; /\* Shifting c and u *\/ */
                   1827: /*     u = *cx; */
                   1828: /*     *cx = dum; */
                   1829: /*     dum = fu; */
                   1830: /*     fu = *fc; */
                   1831: /*     *fc =dum; */
                   1832: /*       } else { /\* end *\/ */
                   1833: /* #ifdef DEBUG */
                   1834: /*       printf("mnbrak3  fu < fc \n"); */
                   1835: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1836: /* #endif */
                   1837: /*     dum=u; /\* Shifting c and u *\/ */
                   1838: /*     u = *cx; */
                   1839: /*     *cx = dum; */
                   1840: /*     dum = fu; */
                   1841: /*     fu = *fc; */
                   1842: /*     *fc =dum; */
                   1843: /*       } */
1.224     brouard  1844: #ifdef DEBUGMNBRAK
                   1845:                 double A, fparabu; 
                   1846:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1847:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1848:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1849:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1850: #endif
1.191     brouard  1851:       dum=u; /* Shifting c and u */
                   1852:       u = *cx;
                   1853:       *cx = dum;
                   1854:       dum = fu;
                   1855:       fu = *fc;
                   1856:       *fc =dum;
1.183     brouard  1857: #endif
1.162     brouard  1858:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1859: #ifdef DEBUG
1.224     brouard  1860:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1861:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1862: #endif
1.126     brouard  1863:       fu=(*func)(u); 
                   1864:       if (fu < *fc) { 
1.183     brouard  1865: #ifdef DEBUG
1.224     brouard  1866:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1867:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1868: #endif
                   1869:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1870:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1871: #ifdef DEBUG
                   1872:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1873: #endif
                   1874:       } 
1.162     brouard  1875:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1876: #ifdef DEBUG
1.224     brouard  1877:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1878:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1879: #endif
1.126     brouard  1880:       u=ulim; 
                   1881:       fu=(*func)(u); 
1.183     brouard  1882:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1883: #ifdef DEBUG
1.224     brouard  1884:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1885:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1886: #endif
1.126     brouard  1887:       u=(*cx)+GOLD*(*cx-*bx); 
                   1888:       fu=(*func)(u); 
1.224     brouard  1889: #ifdef DEBUG
                   1890:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1891:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1892: #endif
1.183     brouard  1893:     } /* end tests */
1.126     brouard  1894:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1895:     SHFT(*fa,*fb,*fc,fu) 
                   1896: #ifdef DEBUG
1.224     brouard  1897:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1898:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1899: #endif
                   1900:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1901: } 
                   1902: 
                   1903: /*************** linmin ************************/
1.162     brouard  1904: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1905: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1906: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1907: the value of func at the returned location p . This is actually all accomplished by calling the
                   1908: routines mnbrak and brent .*/
1.126     brouard  1909: int ncom; 
                   1910: double *pcom,*xicom;
                   1911: double (*nrfunc)(double []); 
                   1912:  
1.224     brouard  1913: #ifdef LINMINORIGINAL
1.126     brouard  1914: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1915: #else
                   1916: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1917: #endif
1.126     brouard  1918: { 
                   1919:   double brent(double ax, double bx, double cx, 
                   1920:               double (*f)(double), double tol, double *xmin); 
                   1921:   double f1dim(double x); 
                   1922:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1923:              double *fc, double (*func)(double)); 
                   1924:   int j; 
                   1925:   double xx,xmin,bx,ax; 
                   1926:   double fx,fb,fa;
1.187     brouard  1927: 
1.203     brouard  1928: #ifdef LINMINORIGINAL
                   1929: #else
                   1930:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1931: #endif
                   1932:   
1.126     brouard  1933:   ncom=n; 
                   1934:   pcom=vector(1,n); 
                   1935:   xicom=vector(1,n); 
                   1936:   nrfunc=func; 
                   1937:   for (j=1;j<=n;j++) { 
                   1938:     pcom[j]=p[j]; 
1.202     brouard  1939:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  1940:   } 
1.187     brouard  1941: 
1.203     brouard  1942: #ifdef LINMINORIGINAL
                   1943:   xx=1.;
                   1944: #else
                   1945:   axs=0.0;
                   1946:   xxs=1.;
                   1947:   do{
                   1948:     xx= xxs;
                   1949: #endif
1.187     brouard  1950:     ax=0.;
                   1951:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   1952:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   1953:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   1954:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   1955:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   1956:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   1957:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  1958: #ifdef LINMINORIGINAL
                   1959: #else
                   1960:     if (fx != fx){
1.224     brouard  1961:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   1962:                        printf("|");
                   1963:                        fprintf(ficlog,"|");
1.203     brouard  1964: #ifdef DEBUGLINMIN
1.224     brouard  1965:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  1966: #endif
                   1967:     }
1.224     brouard  1968:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  1969: #endif
                   1970:   
1.191     brouard  1971: #ifdef DEBUGLINMIN
                   1972:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  1973:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  1974: #endif
1.224     brouard  1975: #ifdef LINMINORIGINAL
                   1976: #else
                   1977:        if(fb == fx){ /* Flat function in the direction */
                   1978:                xmin=xx;
                   1979:     *flat=1;
                   1980:        }else{
                   1981:     *flat=0;
                   1982: #endif
                   1983:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  1984:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   1985:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   1986:   /* fmin = f(p[j] + xmin * xi[j]) */
                   1987:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   1988:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  1989: #ifdef DEBUG
1.224     brouard  1990:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   1991:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   1992: #endif
                   1993: #ifdef LINMINORIGINAL
                   1994: #else
                   1995:                        }
1.126     brouard  1996: #endif
1.191     brouard  1997: #ifdef DEBUGLINMIN
                   1998:   printf("linmin end ");
1.202     brouard  1999:   fprintf(ficlog,"linmin end ");
1.191     brouard  2000: #endif
1.126     brouard  2001:   for (j=1;j<=n;j++) { 
1.203     brouard  2002: #ifdef LINMINORIGINAL
                   2003:     xi[j] *= xmin; 
                   2004: #else
                   2005: #ifdef DEBUGLINMIN
                   2006:     if(xxs <1.0)
                   2007:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2008: #endif
                   2009:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2010: #ifdef DEBUGLINMIN
                   2011:     if(xxs <1.0)
                   2012:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2013: #endif
                   2014: #endif
1.187     brouard  2015:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2016:   } 
1.191     brouard  2017: #ifdef DEBUGLINMIN
1.203     brouard  2018:   printf("\n");
1.191     brouard  2019:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2020:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2021:   for (j=1;j<=n;j++) { 
1.202     brouard  2022:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2023:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2024:     if(j % ncovmodel == 0){
1.191     brouard  2025:       printf("\n");
1.202     brouard  2026:       fprintf(ficlog,"\n");
                   2027:     }
1.191     brouard  2028:   }
1.203     brouard  2029: #else
1.191     brouard  2030: #endif
1.126     brouard  2031:   free_vector(xicom,1,n); 
                   2032:   free_vector(pcom,1,n); 
                   2033: } 
                   2034: 
                   2035: 
                   2036: /*************** powell ************************/
1.162     brouard  2037: /*
                   2038: Minimization of a function func of n variables. Input consists of an initial starting point
                   2039: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2040: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2041: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2042: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2043: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2044:  */
1.224     brouard  2045: #ifdef LINMINORIGINAL
                   2046: #else
                   2047:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2048:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2049: #endif
1.126     brouard  2050: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2051:            double (*func)(double [])) 
                   2052: { 
1.224     brouard  2053: #ifdef LINMINORIGINAL
                   2054:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2055:              double (*func)(double [])); 
1.224     brouard  2056: #else 
                   2057:  void linmin(double p[], double xi[], int n, double *fret, 
                   2058:                                                 double (*func)(double []),int *flat); 
                   2059: #endif
1.126     brouard  2060:   int i,ibig,j; 
                   2061:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2062:   double directest;
1.126     brouard  2063:   double fp,fptt;
                   2064:   double *xits;
                   2065:   int niterf, itmp;
1.224     brouard  2066: #ifdef LINMINORIGINAL
                   2067: #else
                   2068: 
                   2069:   flatdir=ivector(1,n); 
                   2070:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2071: #endif
1.126     brouard  2072: 
                   2073:   pt=vector(1,n); 
                   2074:   ptt=vector(1,n); 
                   2075:   xit=vector(1,n); 
                   2076:   xits=vector(1,n); 
                   2077:   *fret=(*func)(p); 
                   2078:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2079:   rcurr_time = time(NULL);  
1.126     brouard  2080:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2081:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2082:     ibig=0; 
                   2083:     del=0.0; 
1.157     brouard  2084:     rlast_time=rcurr_time;
                   2085:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2086:     rcurr_time = time(NULL);  
                   2087:     curr_time = *localtime(&rcurr_time);
                   2088:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2089:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2090: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2091:     for (i=1;i<=n;i++) {
1.126     brouard  2092:       printf(" %d %.12f",i, p[i]);
                   2093:       fprintf(ficlog," %d %.12lf",i, p[i]);
                   2094:       fprintf(ficrespow," %.12lf", p[i]);
                   2095:     }
                   2096:     printf("\n");
                   2097:     fprintf(ficlog,"\n");
                   2098:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2099:     if(*iter <=3){
1.157     brouard  2100:       tml = *localtime(&rcurr_time);
                   2101:       strcpy(strcurr,asctime(&tml));
                   2102:       rforecast_time=rcurr_time; 
1.126     brouard  2103:       itmp = strlen(strcurr);
                   2104:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.224     brouard  2105:                                strcurr[itmp-1]='\0';
1.162     brouard  2106:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2107:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2108:       for(niterf=10;niterf<=30;niterf+=10){
1.224     brouard  2109:                                rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2110:                                forecast_time = *localtime(&rforecast_time);
                   2111:                                strcpy(strfor,asctime(&forecast_time));
                   2112:                                itmp = strlen(strfor);
                   2113:                                if(strfor[itmp-1]=='\n')
                   2114:                                        strfor[itmp-1]='\0';
                   2115:                                printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2116:                                fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2117:       }
                   2118:     }
1.187     brouard  2119:     for (i=1;i<=n;i++) { /* For each direction i */
                   2120:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2121:       fptt=(*fret); 
                   2122: #ifdef DEBUG
1.203     brouard  2123:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2124:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2125: #endif
1.203     brouard  2126:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2127:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2128: #ifdef LINMINORIGINAL
1.188     brouard  2129:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2130: #else
                   2131:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2132:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2133: #endif
                   2134:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2135:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2136:                                /* because that direction will be replaced unless the gain del is small */
                   2137:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2138:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2139:                                /* with the new direction. */
                   2140:                                del=fabs(fptt-(*fret)); 
                   2141:                                ibig=i; 
1.126     brouard  2142:       } 
                   2143: #ifdef DEBUG
                   2144:       printf("%d %.12e",i,(*fret));
                   2145:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2146:       for (j=1;j<=n;j++) {
1.224     brouard  2147:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2148:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2149:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2150:       }
                   2151:       for(j=1;j<=n;j++) {
1.225     brouard  2152:                                printf(" p(%d)=%.12e",j,p[j]);
                   2153:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2154:       }
                   2155:       printf("\n");
                   2156:       fprintf(ficlog,"\n");
                   2157: #endif
1.187     brouard  2158:     } /* end loop on each direction i */
                   2159:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2160:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2161:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2162:       for(j=1;j<=n;j++) {
1.225     brouard  2163:                                if(flatdir[j] >0){
                   2164:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2165:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2166:                                }
                   2167:                                /* printf("\n"); */
                   2168:                                /* fprintf(ficlog,"\n"); */
                   2169:                        }
1.182     brouard  2170:     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /* Did we reach enough precision? */
1.188     brouard  2171:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2172:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2173:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2174:       /* decreased of more than 3.84  */
                   2175:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2176:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2177:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2178:                        
1.188     brouard  2179:       /* Starting the program with initial values given by a former maximization will simply change */
                   2180:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2181:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2182:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2183: #ifdef DEBUG
                   2184:       int k[2],l;
                   2185:       k[0]=1;
                   2186:       k[1]=-1;
                   2187:       printf("Max: %.12e",(*func)(p));
                   2188:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2189:       for (j=1;j<=n;j++) {
                   2190:        printf(" %.12e",p[j]);
                   2191:        fprintf(ficlog," %.12e",p[j]);
                   2192:       }
                   2193:       printf("\n");
                   2194:       fprintf(ficlog,"\n");
                   2195:       for(l=0;l<=1;l++) {
                   2196:        for (j=1;j<=n;j++) {
                   2197:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2198:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2199:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2200:        }
                   2201:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2202:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2203:       }
                   2204: #endif
                   2205: 
1.224     brouard  2206: #ifdef LINMINORIGINAL
                   2207: #else
                   2208:       free_ivector(flatdir,1,n); 
                   2209: #endif
1.126     brouard  2210:       free_vector(xit,1,n); 
                   2211:       free_vector(xits,1,n); 
                   2212:       free_vector(ptt,1,n); 
                   2213:       free_vector(pt,1,n); 
                   2214:       return; 
1.192     brouard  2215:     } /* enough precision */ 
1.126     brouard  2216:     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2217:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2218:       ptt[j]=2.0*p[j]-pt[j]; 
                   2219:       xit[j]=p[j]-pt[j]; 
                   2220:       pt[j]=p[j]; 
                   2221:     } 
1.181     brouard  2222:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2223: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2224:                if (*iter <=4) {
1.225     brouard  2225: #else
                   2226: #endif
1.224     brouard  2227: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2228: #else
1.161     brouard  2229:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2230: #endif
1.162     brouard  2231:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2232:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2233:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2234:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2235:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2236:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2237:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2238:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2239:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2240:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2241:       /* mu² and del² are equal when f3=f1 */
                   2242:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2243:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2244:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2245:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2246: #ifdef NRCORIGINAL
                   2247:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2248: #else
                   2249:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2250:       t= t- del*SQR(fp-fptt);
1.183     brouard  2251: #endif
1.202     brouard  2252:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2253: #ifdef DEBUG
1.181     brouard  2254:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2255:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2256:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2257:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2258:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2259:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2260:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2261:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2262: #endif
1.183     brouard  2263: #ifdef POWELLORIGINAL
                   2264:       if (t < 0.0) { /* Then we use it for new direction */
                   2265: #else
1.182     brouard  2266:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2267:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2268:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2269:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2270:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2271:       } 
1.181     brouard  2272:       if (directest < 0.0) { /* Then we use it for new direction */
                   2273: #endif
1.191     brouard  2274: #ifdef DEBUGLINMIN
1.234     brouard  2275:        printf("Before linmin in direction P%d-P0\n",n);
                   2276:        for (j=1;j<=n;j++) {
                   2277:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2278:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2279:          if(j % ncovmodel == 0){
                   2280:            printf("\n");
                   2281:            fprintf(ficlog,"\n");
                   2282:          }
                   2283:        }
1.224     brouard  2284: #endif
                   2285: #ifdef LINMINORIGINAL
1.234     brouard  2286:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2287: #else
1.234     brouard  2288:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2289:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2290: #endif
1.234     brouard  2291:        
1.191     brouard  2292: #ifdef DEBUGLINMIN
1.234     brouard  2293:        for (j=1;j<=n;j++) { 
                   2294:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2295:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2296:          if(j % ncovmodel == 0){
                   2297:            printf("\n");
                   2298:            fprintf(ficlog,"\n");
                   2299:          }
                   2300:        }
1.224     brouard  2301: #endif
1.234     brouard  2302:        for (j=1;j<=n;j++) { 
                   2303:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2304:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2305:        }
1.224     brouard  2306: #ifdef LINMINORIGINAL
                   2307: #else
1.234     brouard  2308:        for (j=1, flatd=0;j<=n;j++) {
                   2309:          if(flatdir[j]>0)
                   2310:            flatd++;
                   2311:        }
                   2312:        if(flatd >0){
                   2313:          printf("%d flat directions\n",flatd);
                   2314:          fprintf(ficlog,"%d flat directions\n",flatd);
                   2315:          for (j=1;j<=n;j++) { 
                   2316:            if(flatdir[j]>0){
                   2317:              printf("%d ",j);
                   2318:              fprintf(ficlog,"%d ",j);
                   2319:            }
                   2320:          }
                   2321:          printf("\n");
                   2322:          fprintf(ficlog,"\n");
                   2323:        }
1.191     brouard  2324: #endif
1.234     brouard  2325:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2326:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2327:        
1.126     brouard  2328: #ifdef DEBUG
1.234     brouard  2329:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2330:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2331:        for(j=1;j<=n;j++){
                   2332:          printf(" %lf",xit[j]);
                   2333:          fprintf(ficlog," %lf",xit[j]);
                   2334:        }
                   2335:        printf("\n");
                   2336:        fprintf(ficlog,"\n");
1.126     brouard  2337: #endif
1.192     brouard  2338:       } /* end of t or directest negative */
1.224     brouard  2339: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2340: #else
1.234     brouard  2341:       } /* end if (fptt < fp)  */
1.192     brouard  2342: #endif
1.225     brouard  2343: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2344:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2345: #else
1.224     brouard  2346: #endif
1.234     brouard  2347:                } /* loop iteration */ 
1.126     brouard  2348: } 
1.234     brouard  2349:   
1.126     brouard  2350: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2351:   
1.235     brouard  2352:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2353:   {
1.235     brouard  2354:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2355:        (and selected quantitative values in nres)
                   2356:        by left multiplying the unit
1.234     brouard  2357:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2358:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2359:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2360:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2361:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2362:   /* Initial matrix pimij */
                   2363:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2364:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2365:   /*  0,                   0                  , 1} */
                   2366:   /*
                   2367:    * and after some iteration: */
                   2368:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2369:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2370:   /*  0,                   0                  , 1} */
                   2371:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2372:   /* {0.51571254859325999, 0.4842874514067399, */
                   2373:   /*  0.51326036147820708, 0.48673963852179264} */
                   2374:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2375:     
1.126     brouard  2376:   int i, ii,j,k;
1.209     brouard  2377:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2378:   /* double **matprod2(); */ /* test */
1.218     brouard  2379:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2380:   double **newm;
1.209     brouard  2381:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2382:   int ncvloop=0;
1.169     brouard  2383:   
1.209     brouard  2384:   min=vector(1,nlstate);
                   2385:   max=vector(1,nlstate);
                   2386:   meandiff=vector(1,nlstate);
                   2387: 
1.218     brouard  2388:        /* Starting with matrix unity */
1.126     brouard  2389:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2390:     for (j=1;j<=nlstate+ndeath;j++){
                   2391:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2392:     }
1.169     brouard  2393:   
                   2394:   cov[1]=1.;
                   2395:   
                   2396:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2397:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2398:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2399:     ncvloop++;
1.126     brouard  2400:     newm=savm;
                   2401:     /* Covariates have to be included here again */
1.138     brouard  2402:     cov[2]=agefin;
1.187     brouard  2403:     if(nagesqr==1)
                   2404:       cov[3]= agefin*agefin;;
1.234     brouard  2405:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2406:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2407:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2408:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2409:     }
                   2410:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2411:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2412:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2413:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2414:     }
1.237   ! brouard  2415:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2416:       if(Dummy[Tvar[Tage[k]]]){
                   2417:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2418:       } else{
1.235     brouard  2419:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2420:       }
1.235     brouard  2421:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2422:     }
1.237   ! brouard  2423:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2424:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237   ! brouard  2425:       if(Dummy[Tvard[k][1]==0]){
        !          2426:        if(Dummy[Tvard[k][2]==0]){
        !          2427:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
        !          2428:        }else{
        !          2429:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
        !          2430:        }
        !          2431:       }else{
        !          2432:        if(Dummy[Tvard[k][2]==0]){
        !          2433:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
        !          2434:        }else{
        !          2435:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
        !          2436:        }
        !          2437:       }
1.234     brouard  2438:     }
1.138     brouard  2439:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2440:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2441:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2442:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2443:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2444:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2445:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2446:     
1.126     brouard  2447:     savm=oldm;
                   2448:     oldm=newm;
1.209     brouard  2449: 
                   2450:     for(j=1; j<=nlstate; j++){
                   2451:       max[j]=0.;
                   2452:       min[j]=1.;
                   2453:     }
                   2454:     for(i=1;i<=nlstate;i++){
                   2455:       sumnew=0;
                   2456:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2457:       for(j=1; j<=nlstate; j++){ 
                   2458:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2459:        max[j]=FMAX(max[j],prlim[i][j]);
                   2460:        min[j]=FMIN(min[j],prlim[i][j]);
                   2461:       }
                   2462:     }
                   2463: 
1.126     brouard  2464:     maxmax=0.;
1.209     brouard  2465:     for(j=1; j<=nlstate; j++){
                   2466:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2467:       maxmax=FMAX(maxmax,meandiff[j]);
                   2468:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2469:     } /* j loop */
1.203     brouard  2470:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2471:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2472:     if(maxmax < ftolpl){
1.209     brouard  2473:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2474:       free_vector(min,1,nlstate);
                   2475:       free_vector(max,1,nlstate);
                   2476:       free_vector(meandiff,1,nlstate);
1.126     brouard  2477:       return prlim;
                   2478:     }
1.169     brouard  2479:   } /* age loop */
1.208     brouard  2480:     /* After some age loop it doesn't converge */
1.209     brouard  2481:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2482: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2483:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2484:   free_vector(min,1,nlstate);
                   2485:   free_vector(max,1,nlstate);
                   2486:   free_vector(meandiff,1,nlstate);
1.208     brouard  2487:   
1.169     brouard  2488:   return prlim; /* should not reach here */
1.126     brouard  2489: }
                   2490: 
1.217     brouard  2491: 
                   2492:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2493: 
1.218     brouard  2494:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2495:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2496:  double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij)
1.217     brouard  2497: {
1.218     brouard  2498:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2499:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2500:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2501:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2502:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2503:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2504:   /* Initial matrix pimij */
                   2505:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2506:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2507:   /*  0,                   0                  , 1} */
                   2508:   /*
                   2509:    * and after some iteration: */
                   2510:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2511:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2512:   /*  0,                   0                  , 1} */
                   2513:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2514:   /* {0.51571254859325999, 0.4842874514067399, */
                   2515:   /*  0.51326036147820708, 0.48673963852179264} */
                   2516:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2517: 
                   2518:   int i, ii,j,k;
                   2519:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2520:   /* double **matprod2(); */ /* test */
                   2521:   double **out, cov[NCOVMAX+1], **bmij();
                   2522:   double **newm;
1.218     brouard  2523:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2524:   double        **oldm, **savm;  /* for use */
                   2525: 
1.217     brouard  2526:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2527:   int ncvloop=0;
                   2528:   
                   2529:   min=vector(1,nlstate);
                   2530:   max=vector(1,nlstate);
                   2531:   meandiff=vector(1,nlstate);
                   2532: 
1.218     brouard  2533:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2534:        oldm=oldms; savm=savms;
                   2535: 
                   2536:        /* Starting with matrix unity */
                   2537:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2538:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2539:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2540:     }
                   2541:   
                   2542:   cov[1]=1.;
                   2543:   
                   2544:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2545:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2546:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2547:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2548:     ncvloop++;
1.218     brouard  2549:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2550:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2551:     /* Covariates have to be included here again */
                   2552:     cov[2]=agefin;
                   2553:     if(nagesqr==1)
                   2554:       cov[3]= agefin*agefin;;
                   2555:     for (k=1; k<=cptcovn;k++) {
                   2556:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
                   2557:       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   2558:       /* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); */
                   2559:     }
                   2560:     for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2];
                   2561:     for (k=1; k<=cptcovprod;k++) /* Useless */
                   2562:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
                   2563:       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2564:     
                   2565:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2566:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2567:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2568:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2569:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2570:                /* ij should be linked to the correct index of cov */
                   2571:                /* age and covariate values ij are in 'cov', but we need to pass
                   2572:                 * ij for the observed prevalence at age and status and covariate
                   2573:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2574:                 */
                   2575:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2576:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2577:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2578:     savm=oldm;
                   2579:     oldm=newm;
                   2580:     for(j=1; j<=nlstate; j++){
                   2581:       max[j]=0.;
                   2582:       min[j]=1.;
                   2583:     }
                   2584:     for(j=1; j<=nlstate; j++){ 
                   2585:       for(i=1;i<=nlstate;i++){
1.234     brouard  2586:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2587:        bprlim[i][j]= newm[i][j];
                   2588:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2589:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2590:       }
                   2591:     }
1.218     brouard  2592:                
1.217     brouard  2593:     maxmax=0.;
                   2594:     for(i=1; i<=nlstate; i++){
                   2595:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2596:       maxmax=FMAX(maxmax,meandiff[i]);
                   2597:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2598:     } /* j loop */
                   2599:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2600:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2601:     if(maxmax < ftolpl){
1.220     brouard  2602:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2603:       free_vector(min,1,nlstate);
                   2604:       free_vector(max,1,nlstate);
                   2605:       free_vector(meandiff,1,nlstate);
                   2606:       return bprlim;
                   2607:     }
                   2608:   } /* age loop */
                   2609:     /* After some age loop it doesn't converge */
                   2610:   printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
                   2611: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2612:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2613:   free_vector(min,1,nlstate);
                   2614:   free_vector(max,1,nlstate);
                   2615:   free_vector(meandiff,1,nlstate);
                   2616:   
                   2617:   return bprlim; /* should not reach here */
                   2618: }
                   2619: 
1.126     brouard  2620: /*************** transition probabilities ***************/ 
                   2621: 
                   2622: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2623: {
1.138     brouard  2624:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2625:      computes the probability to be observed in state j being in state i by appying the
                   2626:      model to the ncovmodel covariates (including constant and age).
                   2627:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2628:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2629:      ncth covariate in the global vector x is given by the formula:
                   2630:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2631:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2632:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2633:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2634:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2635:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2636:   */
                   2637:   double s1, lnpijopii;
1.126     brouard  2638:   /*double t34;*/
1.164     brouard  2639:   int i,j, nc, ii, jj;
1.126     brouard  2640: 
1.223     brouard  2641:   for(i=1; i<= nlstate; i++){
                   2642:     for(j=1; j<i;j++){
                   2643:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2644:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2645:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2646:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2647:       }
                   2648:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2649:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2650:     }
                   2651:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2652:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2653:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2654:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2655:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2656:       }
                   2657:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2658:     }
                   2659:   }
1.218     brouard  2660:   
1.223     brouard  2661:   for(i=1; i<= nlstate; i++){
                   2662:     s1=0;
                   2663:     for(j=1; j<i; j++){
                   2664:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2665:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2666:     }
                   2667:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2668:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2669:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2670:     }
                   2671:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2672:     ps[i][i]=1./(s1+1.);
                   2673:     /* Computing other pijs */
                   2674:     for(j=1; j<i; j++)
                   2675:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2676:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2677:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2678:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2679:   } /* end i */
1.218     brouard  2680:   
1.223     brouard  2681:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2682:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2683:       ps[ii][jj]=0;
                   2684:       ps[ii][ii]=1;
                   2685:     }
                   2686:   }
1.218     brouard  2687:   
                   2688:   
1.223     brouard  2689:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2690:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2691:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2692:   /*   } */
                   2693:   /*   printf("\n "); */
                   2694:   /* } */
                   2695:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2696:   /*
                   2697:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2698:                goto end;*/
1.223     brouard  2699:   return ps;
1.126     brouard  2700: }
                   2701: 
1.218     brouard  2702: /*************** backward transition probabilities ***************/ 
                   2703: 
                   2704:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2705: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2706:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2707: {
1.222     brouard  2708:   /* Computes the backward probability at age agefin and covariate ij
                   2709:    * and returns in **ps as well as **bmij.
                   2710:    */
1.218     brouard  2711:   int i, ii, j,k;
1.222     brouard  2712:   
                   2713:   double **out, **pmij();
                   2714:   double sumnew=0.;
1.218     brouard  2715:   double agefin;
1.222     brouard  2716:   
                   2717:   double **dnewm, **dsavm, **doldm;
                   2718:   double **bbmij;
                   2719:   
1.218     brouard  2720:   doldm=ddoldms; /* global pointers */
1.222     brouard  2721:   dnewm=ddnewms;
                   2722:   dsavm=ddsavms;
                   2723:   
                   2724:   agefin=cov[2];
                   2725:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2726:      the observed prevalence (with this covariate ij) */
                   2727:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2728:   /* We do have the matrix Px in savm  and we need pij */
                   2729:   for (j=1;j<=nlstate+ndeath;j++){
                   2730:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2731:     for (ii=1;ii<=nlstate;ii++){
                   2732:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2733:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2734:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2735:       if(sumnew >= 1.e-10){
                   2736:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2737:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2738:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2739:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2740:        /* }else */
                   2741:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2742:       }else{
                   2743:        printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin);
                   2744:       }
                   2745:     } /*End ii */
                   2746:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2747:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2748:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2749:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2750:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2751:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2752:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2753:   for (j=1;j<=nlstate+ndeath;j++){
                   2754:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2755:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2756:     }
                   2757:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2758:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2759:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2760:   /* end bmij */
                   2761:   return ps; 
1.218     brouard  2762: }
1.217     brouard  2763: /*************** transition probabilities ***************/ 
                   2764: 
1.218     brouard  2765: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2766: {
                   2767:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2768:      computes the probability to be observed in state j being in state i by appying the
                   2769:      model to the ncovmodel covariates (including constant and age).
                   2770:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2771:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2772:      ncth covariate in the global vector x is given by the formula:
                   2773:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2774:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2775:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2776:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2777:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2778:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2779:   */
                   2780:   double s1, lnpijopii;
                   2781:   /*double t34;*/
                   2782:   int i,j, nc, ii, jj;
                   2783: 
1.234     brouard  2784:   for(i=1; i<= nlstate; i++){
                   2785:     for(j=1; j<i;j++){
                   2786:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2787:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2788:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2789:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2790:       }
                   2791:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2792:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2793:     }
                   2794:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2795:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2796:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2797:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2798:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2799:       }
                   2800:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2801:     }
                   2802:   }
                   2803:   
                   2804:   for(i=1; i<= nlstate; i++){
                   2805:     s1=0;
                   2806:     for(j=1; j<i; j++){
                   2807:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2808:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2809:     }
                   2810:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2811:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2812:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2813:     }
                   2814:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2815:     ps[i][i]=1./(s1+1.);
                   2816:     /* Computing other pijs */
                   2817:     for(j=1; j<i; j++)
                   2818:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2819:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2820:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2821:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2822:   } /* end i */
                   2823:   
                   2824:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2825:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2826:       ps[ii][jj]=0;
                   2827:       ps[ii][ii]=1;
                   2828:     }
                   2829:   }
                   2830:   /* Added for backcast */ /* Transposed matrix too */
                   2831:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2832:     s1=0.;
                   2833:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2834:       s1+=ps[ii][jj];
                   2835:     }
                   2836:     for(ii=1; ii<= nlstate; ii++){
                   2837:       ps[ii][jj]=ps[ii][jj]/s1;
                   2838:     }
                   2839:   }
                   2840:   /* Transposition */
                   2841:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2842:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2843:       s1=ps[ii][jj];
                   2844:       ps[ii][jj]=ps[jj][ii];
                   2845:       ps[jj][ii]=s1;
                   2846:     }
                   2847:   }
                   2848:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2849:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2850:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2851:   /*   } */
                   2852:   /*   printf("\n "); */
                   2853:   /* } */
                   2854:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2855:   /*
                   2856:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2857:     goto end;*/
                   2858:   return ps;
1.217     brouard  2859: }
                   2860: 
                   2861: 
1.126     brouard  2862: /**************** Product of 2 matrices ******************/
                   2863: 
1.145     brouard  2864: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  2865: {
                   2866:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   2867:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   2868:   /* in, b, out are matrice of pointers which should have been initialized 
                   2869:      before: only the contents of out is modified. The function returns
                   2870:      a pointer to pointers identical to out */
1.145     brouard  2871:   int i, j, k;
1.126     brouard  2872:   for(i=nrl; i<= nrh; i++)
1.145     brouard  2873:     for(k=ncolol; k<=ncoloh; k++){
                   2874:       out[i][k]=0.;
                   2875:       for(j=ncl; j<=nch; j++)
                   2876:        out[i][k] +=in[i][j]*b[j][k];
                   2877:     }
1.126     brouard  2878:   return out;
                   2879: }
                   2880: 
                   2881: 
                   2882: /************* Higher Matrix Product ***************/
                   2883: 
1.235     brouard  2884: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  2885: {
1.218     brouard  2886:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  2887:      'nhstepm*hstepm*stepm' months (i.e. until
                   2888:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   2889:      nhstepm*hstepm matrices. 
                   2890:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   2891:      (typically every 2 years instead of every month which is too big 
                   2892:      for the memory).
                   2893:      Model is determined by parameters x and covariates have to be 
                   2894:      included manually here. 
                   2895: 
                   2896:      */
                   2897: 
                   2898:   int i, j, d, h, k;
1.131     brouard  2899:   double **out, cov[NCOVMAX+1];
1.126     brouard  2900:   double **newm;
1.187     brouard  2901:   double agexact;
1.214     brouard  2902:   double agebegin, ageend;
1.126     brouard  2903: 
                   2904:   /* Hstepm could be zero and should return the unit matrix */
                   2905:   for (i=1;i<=nlstate+ndeath;i++)
                   2906:     for (j=1;j<=nlstate+ndeath;j++){
                   2907:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   2908:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   2909:     }
                   2910:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2911:   for(h=1; h <=nhstepm; h++){
                   2912:     for(d=1; d <=hstepm; d++){
                   2913:       newm=savm;
                   2914:       /* Covariates have to be included here again */
                   2915:       cov[1]=1.;
1.214     brouard  2916:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  2917:       cov[2]=agexact;
                   2918:       if(nagesqr==1)
1.227     brouard  2919:        cov[3]= agexact*agexact;
1.235     brouard  2920:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2921:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2922:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2923:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2924:       }
                   2925:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2926:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2927:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2928:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2929:       }
                   2930:       for (k=1; k<=cptcovage;k++){
                   2931:        if(Dummy[Tvar[Tage[k]]]){
                   2932:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2933:        } else{
                   2934:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2935:        }
                   2936:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2937:       }
                   2938:       for (k=1; k<=cptcovprod;k++){ /*  */
                   2939:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2940:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2941:       }
                   2942:       /* for (k=1; k<=cptcovn;k++)  */
                   2943:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2944:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   2945:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   2946:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   2947:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  2948:       
                   2949:       
1.126     brouard  2950:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   2951:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  2952:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  2953:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   2954:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  2955:       /* if((int)age == 70){ */
                   2956:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   2957:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   2958:       /*         printf("%d pmmij ",i); */
                   2959:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2960:       /*           printf("%f ",pmmij[i][j]); */
                   2961:       /*         } */
                   2962:       /*         printf(" oldm "); */
                   2963:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2964:       /*           printf("%f ",oldm[i][j]); */
                   2965:       /*         } */
                   2966:       /*         printf("\n"); */
                   2967:       /*       } */
                   2968:       /* } */
1.126     brouard  2969:       savm=oldm;
                   2970:       oldm=newm;
                   2971:     }
                   2972:     for(i=1; i<=nlstate+ndeath; i++)
                   2973:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  2974:                                po[i][j][h]=newm[i][j];
                   2975:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  2976:       }
1.128     brouard  2977:     /*printf("h=%d ",h);*/
1.126     brouard  2978:   } /* end h */
1.218     brouard  2979:        /*     printf("\n H=%d \n",h); */
1.126     brouard  2980:   return po;
                   2981: }
                   2982: 
1.217     brouard  2983: /************* Higher Back Matrix Product ***************/
1.218     brouard  2984: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  2985: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  2986: {
1.218     brouard  2987:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  2988:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  2989:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   2990:      nhstepm*hstepm matrices.
                   2991:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   2992:      (typically every 2 years instead of every month which is too big
1.217     brouard  2993:      for the memory).
1.218     brouard  2994:      Model is determined by parameters x and covariates have to be
                   2995:      included manually here.
1.217     brouard  2996: 
1.222     brouard  2997:   */
1.217     brouard  2998: 
                   2999:   int i, j, d, h, k;
                   3000:   double **out, cov[NCOVMAX+1];
                   3001:   double **newm;
                   3002:   double agexact;
                   3003:   double agebegin, ageend;
1.222     brouard  3004:   double **oldm, **savm;
1.217     brouard  3005: 
1.222     brouard  3006:   oldm=oldms;savm=savms;
1.217     brouard  3007:   /* Hstepm could be zero and should return the unit matrix */
                   3008:   for (i=1;i<=nlstate+ndeath;i++)
                   3009:     for (j=1;j<=nlstate+ndeath;j++){
                   3010:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3011:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3012:     }
                   3013:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3014:   for(h=1; h <=nhstepm; h++){
                   3015:     for(d=1; d <=hstepm; d++){
                   3016:       newm=savm;
                   3017:       /* Covariates have to be included here again */
                   3018:       cov[1]=1.;
                   3019:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3020:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3021:       cov[2]=agexact;
                   3022:       if(nagesqr==1)
1.222     brouard  3023:        cov[3]= agexact*agexact;
1.218     brouard  3024:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3025:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3026:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3027:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3028:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3029:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3030:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3031:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3032:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3033:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3034:                        
                   3035:                        
1.217     brouard  3036:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3037:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3038:       /* Careful transposed matrix */
1.222     brouard  3039:       /* age is in cov[2] */
1.218     brouard  3040:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3041:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3042:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3043:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3044:       /* if((int)age == 70){ */
                   3045:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3046:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3047:       /*         printf("%d pmmij ",i); */
                   3048:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3049:       /*           printf("%f ",pmmij[i][j]); */
                   3050:       /*         } */
                   3051:       /*         printf(" oldm "); */
                   3052:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3053:       /*           printf("%f ",oldm[i][j]); */
                   3054:       /*         } */
                   3055:       /*         printf("\n"); */
                   3056:       /*       } */
                   3057:       /* } */
                   3058:       savm=oldm;
                   3059:       oldm=newm;
                   3060:     }
                   3061:     for(i=1; i<=nlstate+ndeath; i++)
                   3062:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3063:        po[i][j][h]=newm[i][j];
                   3064:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3065:       }
                   3066:     /*printf("h=%d ",h);*/
                   3067:   } /* end h */
1.222     brouard  3068:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3069:   return po;
                   3070: }
                   3071: 
                   3072: 
1.162     brouard  3073: #ifdef NLOPT
                   3074:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3075:   double fret;
                   3076:   double *xt;
                   3077:   int j;
                   3078:   myfunc_data *d2 = (myfunc_data *) pd;
                   3079: /* xt = (p1-1); */
                   3080:   xt=vector(1,n); 
                   3081:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3082: 
                   3083:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3084:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3085:   printf("Function = %.12lf ",fret);
                   3086:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3087:   printf("\n");
                   3088:  free_vector(xt,1,n);
                   3089:   return fret;
                   3090: }
                   3091: #endif
1.126     brouard  3092: 
                   3093: /*************** log-likelihood *************/
                   3094: double func( double *x)
                   3095: {
1.226     brouard  3096:   int i, ii, j, k, mi, d, kk;
                   3097:   int ioffset=0;
                   3098:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3099:   double **out;
                   3100:   double lli; /* Individual log likelihood */
                   3101:   int s1, s2;
1.228     brouard  3102:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3103:   double bbh, survp;
                   3104:   long ipmx;
                   3105:   double agexact;
                   3106:   /*extern weight */
                   3107:   /* We are differentiating ll according to initial status */
                   3108:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3109:   /*for(i=1;i<imx;i++) 
                   3110:     printf(" %d\n",s[4][i]);
                   3111:   */
1.162     brouard  3112: 
1.226     brouard  3113:   ++countcallfunc;
1.162     brouard  3114: 
1.226     brouard  3115:   cov[1]=1.;
1.126     brouard  3116: 
1.226     brouard  3117:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3118:   ioffset=0;
1.226     brouard  3119:   if(mle==1){
                   3120:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3121:       /* Computes the values of the ncovmodel covariates of the model
                   3122:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3123:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3124:         to be observed in j being in i according to the model.
                   3125:       */
                   3126:       ioffset=2+nagesqr+cptcovage;
1.233     brouard  3127:    /* Fixed */
1.234     brouard  3128:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3129:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3130:       }
1.226     brouard  3131:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3132:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3133:         has been calculated etc */
                   3134:       /* For an individual i, wav[i] gives the number of effective waves */
                   3135:       /* We compute the contribution to Likelihood of each effective transition
                   3136:         mw[mi][i] is real wave of the mi th effectve wave */
                   3137:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3138:         s2=s[mw[mi+1][i]][i];
                   3139:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3140:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3141:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3142:       */
                   3143:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3144:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
                   3145:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i];
                   3146:        }
                   3147:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3148:          for (j=1;j<=nlstate+ndeath;j++){
                   3149:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3150:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3151:          }
                   3152:        for(d=0; d<dh[mi][i]; d++){
                   3153:          newm=savm;
                   3154:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3155:          cov[2]=agexact;
                   3156:          if(nagesqr==1)
                   3157:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3158:          for (kk=1; kk<=cptcovage;kk++) {
                   3159:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
                   3160:          }
                   3161:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3162:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3163:          savm=oldm;
                   3164:          oldm=newm;
                   3165:        } /* end mult */
                   3166:        
                   3167:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3168:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3169:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3170:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3171:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3172:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3173:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3174:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3175:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3176:                                 * -stepm/2 to stepm/2 .
                   3177:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3178:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3179:                                 */
1.234     brouard  3180:        s1=s[mw[mi][i]][i];
                   3181:        s2=s[mw[mi+1][i]][i];
                   3182:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3183:        /* bias bh is positive if real duration
                   3184:         * is higher than the multiple of stepm and negative otherwise.
                   3185:         */
                   3186:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3187:        if( s2 > nlstate){ 
                   3188:          /* i.e. if s2 is a death state and if the date of death is known 
                   3189:             then the contribution to the likelihood is the probability to 
                   3190:             die between last step unit time and current  step unit time, 
                   3191:             which is also equal to probability to die before dh 
                   3192:             minus probability to die before dh-stepm . 
                   3193:             In version up to 0.92 likelihood was computed
                   3194:             as if date of death was unknown. Death was treated as any other
                   3195:             health state: the date of the interview describes the actual state
                   3196:             and not the date of a change in health state. The former idea was
                   3197:             to consider that at each interview the state was recorded
                   3198:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3199:             introduced the exact date of death then we should have modified
                   3200:             the contribution of an exact death to the likelihood. This new
                   3201:             contribution is smaller and very dependent of the step unit
                   3202:             stepm. It is no more the probability to die between last interview
                   3203:             and month of death but the probability to survive from last
                   3204:             interview up to one month before death multiplied by the
                   3205:             probability to die within a month. Thanks to Chris
                   3206:             Jackson for correcting this bug.  Former versions increased
                   3207:             mortality artificially. The bad side is that we add another loop
                   3208:             which slows down the processing. The difference can be up to 10%
                   3209:             lower mortality.
                   3210:          */
                   3211:          /* If, at the beginning of the maximization mostly, the
                   3212:             cumulative probability or probability to be dead is
                   3213:             constant (ie = 1) over time d, the difference is equal to
                   3214:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3215:             s1 at precedent wave, to be dead a month before current
                   3216:             wave is equal to probability, being at state s1 at
                   3217:             precedent wave, to be dead at mont of the current
                   3218:             wave. Then the observed probability (that this person died)
                   3219:             is null according to current estimated parameter. In fact,
                   3220:             it should be very low but not zero otherwise the log go to
                   3221:             infinity.
                   3222:          */
1.183     brouard  3223: /* #ifdef INFINITYORIGINAL */
                   3224: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3225: /* #else */
                   3226: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3227: /*         lli=log(mytinydouble); */
                   3228: /*       else */
                   3229: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3230: /* #endif */
1.226     brouard  3231:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3232:          
1.226     brouard  3233:        } else if  ( s2==-1 ) { /* alive */
                   3234:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3235:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3236:          /*survp += out[s1][j]; */
                   3237:          lli= log(survp);
                   3238:        }
                   3239:        else if  (s2==-4) { 
                   3240:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3241:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3242:          lli= log(survp); 
                   3243:        } 
                   3244:        else if  (s2==-5) { 
                   3245:          for (j=1,survp=0. ; j<=2; j++)  
                   3246:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3247:          lli= log(survp); 
                   3248:        } 
                   3249:        else{
                   3250:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3251:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3252:        } 
                   3253:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3254:        /*if(lli ==000.0)*/
                   3255:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3256:        ipmx +=1;
                   3257:        sw += weight[i];
                   3258:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3259:        /* if (lli < log(mytinydouble)){ */
                   3260:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3261:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3262:        /* } */
                   3263:       } /* end of wave */
                   3264:     } /* end of individual */
                   3265:   }  else if(mle==2){
                   3266:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3267:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3268:       for(mi=1; mi<= wav[i]-1; mi++){
                   3269:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3270:          for (j=1;j<=nlstate+ndeath;j++){
                   3271:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3272:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3273:          }
                   3274:        for(d=0; d<=dh[mi][i]; d++){
                   3275:          newm=savm;
                   3276:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3277:          cov[2]=agexact;
                   3278:          if(nagesqr==1)
                   3279:            cov[3]= agexact*agexact;
                   3280:          for (kk=1; kk<=cptcovage;kk++) {
                   3281:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3282:          }
                   3283:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3284:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3285:          savm=oldm;
                   3286:          oldm=newm;
                   3287:        } /* end mult */
                   3288:       
                   3289:        s1=s[mw[mi][i]][i];
                   3290:        s2=s[mw[mi+1][i]][i];
                   3291:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3292:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3293:        ipmx +=1;
                   3294:        sw += weight[i];
                   3295:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3296:       } /* end of wave */
                   3297:     } /* end of individual */
                   3298:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3299:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3300:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3301:       for(mi=1; mi<= wav[i]-1; mi++){
                   3302:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3303:          for (j=1;j<=nlstate+ndeath;j++){
                   3304:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3305:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3306:          }
                   3307:        for(d=0; d<dh[mi][i]; d++){
                   3308:          newm=savm;
                   3309:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3310:          cov[2]=agexact;
                   3311:          if(nagesqr==1)
                   3312:            cov[3]= agexact*agexact;
                   3313:          for (kk=1; kk<=cptcovage;kk++) {
                   3314:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3315:          }
                   3316:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3317:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3318:          savm=oldm;
                   3319:          oldm=newm;
                   3320:        } /* end mult */
                   3321:       
                   3322:        s1=s[mw[mi][i]][i];
                   3323:        s2=s[mw[mi+1][i]][i];
                   3324:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3325:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3326:        ipmx +=1;
                   3327:        sw += weight[i];
                   3328:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3329:       } /* end of wave */
                   3330:     } /* end of individual */
                   3331:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3332:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3333:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3334:       for(mi=1; mi<= wav[i]-1; mi++){
                   3335:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3336:          for (j=1;j<=nlstate+ndeath;j++){
                   3337:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3338:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3339:          }
                   3340:        for(d=0; d<dh[mi][i]; d++){
                   3341:          newm=savm;
                   3342:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3343:          cov[2]=agexact;
                   3344:          if(nagesqr==1)
                   3345:            cov[3]= agexact*agexact;
                   3346:          for (kk=1; kk<=cptcovage;kk++) {
                   3347:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3348:          }
1.126     brouard  3349:        
1.226     brouard  3350:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3351:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3352:          savm=oldm;
                   3353:          oldm=newm;
                   3354:        } /* end mult */
                   3355:       
                   3356:        s1=s[mw[mi][i]][i];
                   3357:        s2=s[mw[mi+1][i]][i];
                   3358:        if( s2 > nlstate){ 
                   3359:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3360:        } else if  ( s2==-1 ) { /* alive */
                   3361:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3362:            survp += out[s1][j];
                   3363:          lli= log(survp);
                   3364:        }else{
                   3365:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3366:        }
                   3367:        ipmx +=1;
                   3368:        sw += weight[i];
                   3369:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3370: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3371:       } /* end of wave */
                   3372:     } /* end of individual */
                   3373:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3374:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3375:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3376:       for(mi=1; mi<= wav[i]-1; mi++){
                   3377:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3378:          for (j=1;j<=nlstate+ndeath;j++){
                   3379:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3380:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3381:          }
                   3382:        for(d=0; d<dh[mi][i]; d++){
                   3383:          newm=savm;
                   3384:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3385:          cov[2]=agexact;
                   3386:          if(nagesqr==1)
                   3387:            cov[3]= agexact*agexact;
                   3388:          for (kk=1; kk<=cptcovage;kk++) {
                   3389:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3390:          }
1.126     brouard  3391:        
1.226     brouard  3392:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3393:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3394:          savm=oldm;
                   3395:          oldm=newm;
                   3396:        } /* end mult */
                   3397:       
                   3398:        s1=s[mw[mi][i]][i];
                   3399:        s2=s[mw[mi+1][i]][i];
                   3400:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3401:        ipmx +=1;
                   3402:        sw += weight[i];
                   3403:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3404:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3405:       } /* end of wave */
                   3406:     } /* end of individual */
                   3407:   } /* End of if */
                   3408:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3409:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3410:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3411:   return -l;
1.126     brouard  3412: }
                   3413: 
                   3414: /*************** log-likelihood *************/
                   3415: double funcone( double *x)
                   3416: {
1.228     brouard  3417:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3418:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3419:   int ioffset=0;
1.131     brouard  3420:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3421:   double **out;
                   3422:   double lli; /* Individual log likelihood */
                   3423:   double llt;
                   3424:   int s1, s2;
1.228     brouard  3425:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3426: 
1.126     brouard  3427:   double bbh, survp;
1.187     brouard  3428:   double agexact;
1.214     brouard  3429:   double agebegin, ageend;
1.126     brouard  3430:   /*extern weight */
                   3431:   /* We are differentiating ll according to initial status */
                   3432:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3433:   /*for(i=1;i<imx;i++) 
                   3434:     printf(" %d\n",s[4][i]);
                   3435:   */
                   3436:   cov[1]=1.;
                   3437: 
                   3438:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3439:   ioffset=0;
                   3440:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.225     brouard  3441:     ioffset=2+nagesqr+cptcovage;
1.232     brouard  3442:     /* Fixed */
1.224     brouard  3443:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3444:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3445:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3446:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3447: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3448: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3449: /*    cov[2+6]=covar[2][i]; V2  */
                   3450: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3451: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3452: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3453: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3454: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3455: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3456:     }
1.232     brouard  3457:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3458:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3459:     /* } */
1.231     brouard  3460:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3461:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3462:     /* } */
1.225     brouard  3463:     
1.233     brouard  3464: 
                   3465:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3466:     /* Wave varying (but not age varying) */
                   3467:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.233     brouard  3468:                                cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i];
1.232     brouard  3469:                        }
                   3470:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.231     brouard  3471:                                /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3472:                                /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
1.232     brouard  3473:                                /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3474:                                /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
1.231     brouard  3475:                                /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3476:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
                   3477:                        /*      iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3478:                        /*      /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3479:                        /*      cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
                   3480:       /* } */
1.126     brouard  3481:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.231     brouard  3482:                                for (j=1;j<=nlstate+ndeath;j++){
                   3483:                                        oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3484:                                        savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3485:                                }
1.214     brouard  3486:       
                   3487:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3488:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3489:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.231     brouard  3490:                                /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3491:                                        and mw[mi+1][i]. dh depends on stepm.*/
                   3492:                                newm=savm;
                   3493:                                agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3494:                                cov[2]=agexact;
                   3495:                                if(nagesqr==1)
                   3496:                                        cov[3]= agexact*agexact;
                   3497:                                for (kk=1; kk<=cptcovage;kk++) {
                   3498:                                        cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3499:                                }
                   3500:                                /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3501:                                /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3502:                                out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3503:                                                                                 1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3504:                                /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3505:                                /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3506:                                savm=oldm;
                   3507:                                oldm=newm;
1.126     brouard  3508:       } /* end mult */
                   3509:       
                   3510:       s1=s[mw[mi][i]][i];
                   3511:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3512:       /* if(s2==-1){ */
                   3513:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3514:       /*       /\* exit(1); *\/ */
                   3515:       /* } */
1.126     brouard  3516:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3517:       /* bias is positive if real duration
                   3518:        * is higher than the multiple of stepm and negative otherwise.
                   3519:        */
                   3520:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.232     brouard  3521:                                lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3522:       } else if  ( s2==-1 ) { /* alive */
1.232     brouard  3523:                                for (j=1,survp=0. ; j<=nlstate; j++) 
                   3524:                                        survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3525:                                lli= log(survp);
1.126     brouard  3526:       }else if (mle==1){
1.232     brouard  3527:                                lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3528:       } else if(mle==2){
1.232     brouard  3529:                                lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3530:       } else if(mle==3){  /* exponential inter-extrapolation */
1.232     brouard  3531:                                lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3532:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.232     brouard  3533:                                lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3534:       } else{  /* mle=0 back to 1 */
1.232     brouard  3535:                                lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3536:                                /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3537:       } /* End of if */
                   3538:       ipmx +=1;
                   3539:       sw += weight[i];
                   3540:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3541:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3542:       if(globpr){
1.232     brouard  3543:                                fprintf(ficresilk,"%9ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3544:  %11.6f %11.6f %11.6f ", \
1.232     brouard  3545:                                                                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3546:                                                                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3547:                                for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3548:                                        llt +=ll[k]*gipmx/gsw;
                   3549:                                        fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3550:                                }
                   3551:                                fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3552:       }
1.232     brouard  3553:        } /* end of wave */
                   3554: } /* end of individual */
                   3555: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3556: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3557: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3558: if(globpr==0){ /* First time we count the contributions and weights */
                   3559:        gipmx=ipmx;
                   3560:        gsw=sw;
                   3561: }
                   3562: return -l;
1.126     brouard  3563: }
                   3564: 
                   3565: 
                   3566: /*************** function likelione ***********/
                   3567: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3568: {
                   3569:   /* This routine should help understanding what is done with 
                   3570:      the selection of individuals/waves and
                   3571:      to check the exact contribution to the likelihood.
                   3572:      Plotting could be done.
                   3573:    */
                   3574:   int k;
                   3575: 
                   3576:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3577:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3578:     strcat(fileresilk,fileresu);
1.126     brouard  3579:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3580:       printf("Problem with resultfile: %s\n", fileresilk);
                   3581:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3582:     }
1.214     brouard  3583:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3584:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3585:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3586:     for(k=1; k<=nlstate; k++) 
                   3587:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3588:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3589:   }
                   3590: 
                   3591:   *fretone=(*funcone)(p);
                   3592:   if(*globpri !=0){
                   3593:     fclose(ficresilk);
1.205     brouard  3594:     if (mle ==0)
                   3595:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3596:     else if(mle >=1)
                   3597:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3598:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3599:     
1.208     brouard  3600:       
                   3601:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3602:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3603: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3604:     }
1.207     brouard  3605:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3606: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3607:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3608: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3609:     fflush(fichtm);
1.205     brouard  3610:   }
1.126     brouard  3611:   return;
                   3612: }
                   3613: 
                   3614: 
                   3615: /*********** Maximum Likelihood Estimation ***************/
                   3616: 
                   3617: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3618: {
1.165     brouard  3619:   int i,j, iter=0;
1.126     brouard  3620:   double **xi;
                   3621:   double fret;
                   3622:   double fretone; /* Only one call to likelihood */
                   3623:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3624: 
                   3625: #ifdef NLOPT
                   3626:   int creturn;
                   3627:   nlopt_opt opt;
                   3628:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3629:   double *lb;
                   3630:   double minf; /* the minimum objective value, upon return */
                   3631:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3632:   myfunc_data dinst, *d = &dinst;
                   3633: #endif
                   3634: 
                   3635: 
1.126     brouard  3636:   xi=matrix(1,npar,1,npar);
                   3637:   for (i=1;i<=npar;i++)
                   3638:     for (j=1;j<=npar;j++)
                   3639:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3640:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3641:   strcpy(filerespow,"POW_"); 
1.126     brouard  3642:   strcat(filerespow,fileres);
                   3643:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3644:     printf("Problem with resultfile: %s\n", filerespow);
                   3645:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3646:   }
                   3647:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3648:   for (i=1;i<=nlstate;i++)
                   3649:     for(j=1;j<=nlstate+ndeath;j++)
                   3650:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3651:   fprintf(ficrespow,"\n");
1.162     brouard  3652: #ifdef POWELL
1.126     brouard  3653:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3654: #endif
1.126     brouard  3655: 
1.162     brouard  3656: #ifdef NLOPT
                   3657: #ifdef NEWUOA
                   3658:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3659: #else
                   3660:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3661: #endif
                   3662:   lb=vector(0,npar-1);
                   3663:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3664:   nlopt_set_lower_bounds(opt, lb);
                   3665:   nlopt_set_initial_step1(opt, 0.1);
                   3666:   
                   3667:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3668:   d->function = func;
                   3669:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3670:   nlopt_set_min_objective(opt, myfunc, d);
                   3671:   nlopt_set_xtol_rel(opt, ftol);
                   3672:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3673:     printf("nlopt failed! %d\n",creturn); 
                   3674:   }
                   3675:   else {
                   3676:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3677:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3678:     iter=1; /* not equal */
                   3679:   }
                   3680:   nlopt_destroy(opt);
                   3681: #endif
1.126     brouard  3682:   free_matrix(xi,1,npar,1,npar);
                   3683:   fclose(ficrespow);
1.203     brouard  3684:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3685:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3686:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3687: 
                   3688: }
                   3689: 
                   3690: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3691: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3692: {
                   3693:   double  **a,**y,*x,pd;
1.203     brouard  3694:   /* double **hess; */
1.164     brouard  3695:   int i, j;
1.126     brouard  3696:   int *indx;
                   3697: 
                   3698:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3699:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3700:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3701:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3702:   double gompertz(double p[]);
1.203     brouard  3703:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3704: 
                   3705:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3706:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3707:   for (i=1;i<=npar;i++){
1.203     brouard  3708:     printf("%d-",i);fflush(stdout);
                   3709:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3710:    
                   3711:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3712:     
                   3713:     /*  printf(" %f ",p[i]);
                   3714:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3715:   }
                   3716:   
                   3717:   for (i=1;i<=npar;i++) {
                   3718:     for (j=1;j<=npar;j++)  {
                   3719:       if (j>i) { 
1.203     brouard  3720:        printf(".%d-%d",i,j);fflush(stdout);
                   3721:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3722:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3723:        
                   3724:        hess[j][i]=hess[i][j];    
                   3725:        /*printf(" %lf ",hess[i][j]);*/
                   3726:       }
                   3727:     }
                   3728:   }
                   3729:   printf("\n");
                   3730:   fprintf(ficlog,"\n");
                   3731: 
                   3732:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3733:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3734:   
                   3735:   a=matrix(1,npar,1,npar);
                   3736:   y=matrix(1,npar,1,npar);
                   3737:   x=vector(1,npar);
                   3738:   indx=ivector(1,npar);
                   3739:   for (i=1;i<=npar;i++)
                   3740:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3741:   ludcmp(a,npar,indx,&pd);
                   3742: 
                   3743:   for (j=1;j<=npar;j++) {
                   3744:     for (i=1;i<=npar;i++) x[i]=0;
                   3745:     x[j]=1;
                   3746:     lubksb(a,npar,indx,x);
                   3747:     for (i=1;i<=npar;i++){ 
                   3748:       matcov[i][j]=x[i];
                   3749:     }
                   3750:   }
                   3751: 
                   3752:   printf("\n#Hessian matrix#\n");
                   3753:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3754:   for (i=1;i<=npar;i++) { 
                   3755:     for (j=1;j<=npar;j++) { 
1.203     brouard  3756:       printf("%.6e ",hess[i][j]);
                   3757:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3758:     }
                   3759:     printf("\n");
                   3760:     fprintf(ficlog,"\n");
                   3761:   }
                   3762: 
1.203     brouard  3763:   /* printf("\n#Covariance matrix#\n"); */
                   3764:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3765:   /* for (i=1;i<=npar;i++) {  */
                   3766:   /*   for (j=1;j<=npar;j++) {  */
                   3767:   /*     printf("%.6e ",matcov[i][j]); */
                   3768:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3769:   /*   } */
                   3770:   /*   printf("\n"); */
                   3771:   /*   fprintf(ficlog,"\n"); */
                   3772:   /* } */
                   3773: 
1.126     brouard  3774:   /* Recompute Inverse */
1.203     brouard  3775:   /* for (i=1;i<=npar;i++) */
                   3776:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3777:   /* ludcmp(a,npar,indx,&pd); */
                   3778: 
                   3779:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3780: 
                   3781:   /* for (j=1;j<=npar;j++) { */
                   3782:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3783:   /*   x[j]=1; */
                   3784:   /*   lubksb(a,npar,indx,x); */
                   3785:   /*   for (i=1;i<=npar;i++){  */
                   3786:   /*     y[i][j]=x[i]; */
                   3787:   /*     printf("%.3e ",y[i][j]); */
                   3788:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3789:   /*   } */
                   3790:   /*   printf("\n"); */
                   3791:   /*   fprintf(ficlog,"\n"); */
                   3792:   /* } */
                   3793: 
                   3794:   /* Verifying the inverse matrix */
                   3795: #ifdef DEBUGHESS
                   3796:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3797: 
1.203     brouard  3798:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3799:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3800: 
                   3801:   for (j=1;j<=npar;j++) {
                   3802:     for (i=1;i<=npar;i++){ 
1.203     brouard  3803:       printf("%.2f ",y[i][j]);
                   3804:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3805:     }
                   3806:     printf("\n");
                   3807:     fprintf(ficlog,"\n");
                   3808:   }
1.203     brouard  3809: #endif
1.126     brouard  3810: 
                   3811:   free_matrix(a,1,npar,1,npar);
                   3812:   free_matrix(y,1,npar,1,npar);
                   3813:   free_vector(x,1,npar);
                   3814:   free_ivector(indx,1,npar);
1.203     brouard  3815:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3816: 
                   3817: 
                   3818: }
                   3819: 
                   3820: /*************** hessian matrix ****************/
                   3821: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3822: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3823:   int i;
                   3824:   int l=1, lmax=20;
1.203     brouard  3825:   double k1,k2, res, fx;
1.132     brouard  3826:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3827:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3828:   int k=0,kmax=10;
                   3829:   double l1;
                   3830: 
                   3831:   fx=func(x);
                   3832:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3833:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3834:     l1=pow(10,l);
                   3835:     delts=delt;
                   3836:     for(k=1 ; k <kmax; k=k+1){
                   3837:       delt = delta*(l1*k);
                   3838:       p2[theta]=x[theta] +delt;
1.145     brouard  3839:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3840:       p2[theta]=x[theta]-delt;
                   3841:       k2=func(p2)-fx;
                   3842:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3843:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3844:       
1.203     brouard  3845: #ifdef DEBUGHESSII
1.126     brouard  3846:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3847:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3848: #endif
                   3849:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   3850:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   3851:        k=kmax;
                   3852:       }
                   3853:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  3854:        k=kmax; l=lmax*10;
1.126     brouard  3855:       }
                   3856:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   3857:        delts=delt;
                   3858:       }
1.203     brouard  3859:     } /* End loop k */
1.126     brouard  3860:   }
                   3861:   delti[theta]=delts;
                   3862:   return res; 
                   3863:   
                   3864: }
                   3865: 
1.203     brouard  3866: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  3867: {
                   3868:   int i;
1.164     brouard  3869:   int l=1, lmax=20;
1.126     brouard  3870:   double k1,k2,k3,k4,res,fx;
1.132     brouard  3871:   double p2[MAXPARM+1];
1.203     brouard  3872:   int k, kmax=1;
                   3873:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  3874: 
                   3875:   int firstime=0;
1.203     brouard  3876:   
1.126     brouard  3877:   fx=func(x);
1.203     brouard  3878:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  3879:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  3880:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3881:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3882:     k1=func(p2)-fx;
                   3883:   
1.203     brouard  3884:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   3885:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3886:     k2=func(p2)-fx;
                   3887:   
1.203     brouard  3888:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3889:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  3890:     k3=func(p2)-fx;
                   3891:   
1.203     brouard  3892:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   3893:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  3894:     k4=func(p2)-fx;
1.203     brouard  3895:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   3896:     if(k1*k2*k3*k4 <0.){
1.208     brouard  3897:       firstime=1;
1.203     brouard  3898:       kmax=kmax+10;
1.208     brouard  3899:     }
                   3900:     if(kmax >=10 || firstime ==1){
1.218     brouard  3901:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
                   3902:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you may increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  3903:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3904:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3905:     }
                   3906: #ifdef DEBUGHESSIJ
                   3907:     v1=hess[thetai][thetai];
                   3908:     v2=hess[thetaj][thetaj];
                   3909:     cv12=res;
                   3910:     /* Computing eigen value of Hessian matrix */
                   3911:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   3912:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   3913:     if ((lc2 <0) || (lc1 <0) ){
                   3914:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   3915:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   3916:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3917:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   3918:     }
1.126     brouard  3919: #endif
                   3920:   }
                   3921:   return res;
                   3922: }
                   3923: 
1.203     brouard  3924:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   3925: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   3926: /* { */
                   3927: /*   int i; */
                   3928: /*   int l=1, lmax=20; */
                   3929: /*   double k1,k2,k3,k4,res,fx; */
                   3930: /*   double p2[MAXPARM+1]; */
                   3931: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   3932: /*   int k=0,kmax=10; */
                   3933: /*   double l1; */
                   3934:   
                   3935: /*   fx=func(x); */
                   3936: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   3937: /*     l1=pow(10,l); */
                   3938: /*     delts=delt; */
                   3939: /*     for(k=1 ; k <kmax; k=k+1){ */
                   3940: /*       delt = delti*(l1*k); */
                   3941: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   3942: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   3943: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   3944: /*       k1=func(p2)-fx; */
                   3945:       
                   3946: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   3947: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   3948: /*       k2=func(p2)-fx; */
                   3949:       
                   3950: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   3951: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   3952: /*       k3=func(p2)-fx; */
                   3953:       
                   3954: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   3955: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   3956: /*       k4=func(p2)-fx; */
                   3957: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   3958: /* #ifdef DEBUGHESSIJ */
                   3959: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   3960: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   3961: /* #endif */
                   3962: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   3963: /*     k=kmax; */
                   3964: /*       } */
                   3965: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   3966: /*     k=kmax; l=lmax*10; */
                   3967: /*       } */
                   3968: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   3969: /*     delts=delt; */
                   3970: /*       } */
                   3971: /*     } /\* End loop k *\/ */
                   3972: /*   } */
                   3973: /*   delti[theta]=delts; */
                   3974: /*   return res;  */
                   3975: /* } */
                   3976: 
                   3977: 
1.126     brouard  3978: /************** Inverse of matrix **************/
                   3979: void ludcmp(double **a, int n, int *indx, double *d) 
                   3980: { 
                   3981:   int i,imax,j,k; 
                   3982:   double big,dum,sum,temp; 
                   3983:   double *vv; 
                   3984:  
                   3985:   vv=vector(1,n); 
                   3986:   *d=1.0; 
                   3987:   for (i=1;i<=n;i++) { 
                   3988:     big=0.0; 
                   3989:     for (j=1;j<=n;j++) 
                   3990:       if ((temp=fabs(a[i][j])) > big) big=temp; 
                   3991:     if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
                   3992:     vv[i]=1.0/big; 
                   3993:   } 
                   3994:   for (j=1;j<=n;j++) { 
                   3995:     for (i=1;i<j;i++) { 
                   3996:       sum=a[i][j]; 
                   3997:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   3998:       a[i][j]=sum; 
                   3999:     } 
                   4000:     big=0.0; 
                   4001:     for (i=j;i<=n;i++) { 
                   4002:       sum=a[i][j]; 
                   4003:       for (k=1;k<j;k++) 
                   4004:        sum -= a[i][k]*a[k][j]; 
                   4005:       a[i][j]=sum; 
                   4006:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4007:        big=dum; 
                   4008:        imax=i; 
                   4009:       } 
                   4010:     } 
                   4011:     if (j != imax) { 
                   4012:       for (k=1;k<=n;k++) { 
                   4013:        dum=a[imax][k]; 
                   4014:        a[imax][k]=a[j][k]; 
                   4015:        a[j][k]=dum; 
                   4016:       } 
                   4017:       *d = -(*d); 
                   4018:       vv[imax]=vv[j]; 
                   4019:     } 
                   4020:     indx[j]=imax; 
                   4021:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4022:     if (j != n) { 
                   4023:       dum=1.0/(a[j][j]); 
                   4024:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4025:     } 
                   4026:   } 
                   4027:   free_vector(vv,1,n);  /* Doesn't work */
                   4028: ;
                   4029: } 
                   4030: 
                   4031: void lubksb(double **a, int n, int *indx, double b[]) 
                   4032: { 
                   4033:   int i,ii=0,ip,j; 
                   4034:   double sum; 
                   4035:  
                   4036:   for (i=1;i<=n;i++) { 
                   4037:     ip=indx[i]; 
                   4038:     sum=b[ip]; 
                   4039:     b[ip]=b[i]; 
                   4040:     if (ii) 
                   4041:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4042:     else if (sum) ii=i; 
                   4043:     b[i]=sum; 
                   4044:   } 
                   4045:   for (i=n;i>=1;i--) { 
                   4046:     sum=b[i]; 
                   4047:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4048:     b[i]=sum/a[i][i]; 
                   4049:   } 
                   4050: } 
                   4051: 
                   4052: void pstamp(FILE *fichier)
                   4053: {
1.196     brouard  4054:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4055: }
                   4056: 
                   4057: /************ Frequencies ********************/
1.226     brouard  4058: void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
                   4059:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4060:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
                   4061: {  /* Some frequencies */
                   4062:   
1.227     brouard  4063:   int i, m, jk, j1, bool, z1,j, k, iv;
1.226     brouard  4064:   int iind=0, iage=0;
                   4065:   int mi; /* Effective wave */
                   4066:   int first;
                   4067:   double ***freq; /* Frequencies */
                   4068:   double *meanq;
                   4069:   double **meanqt;
                   4070:   double *pp, **prop, *posprop, *pospropt;
                   4071:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4072:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4073:   double agebegin, ageend;
                   4074:     
                   4075:   pp=vector(1,nlstate);
                   4076:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4077:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4078:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4079:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4080:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4081:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4082:   strcpy(fileresp,"P_");
                   4083:   strcat(fileresp,fileresu);
                   4084:   /*strcat(fileresphtm,fileresu);*/
                   4085:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4086:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4087:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4088:     exit(0);
                   4089:   }
1.214     brouard  4090: 
1.226     brouard  4091:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4092:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4093:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4094:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4095:     fflush(ficlog);
                   4096:     exit(70); 
                   4097:   }
                   4098:   else{
                   4099:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.214     brouard  4100: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   4101: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4102:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4103:   }
1.237   ! brouard  4104:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.214     brouard  4105:     
1.226     brouard  4106:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4107:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4108:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4109:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4110:     fflush(ficlog);
                   4111:     exit(70); 
                   4112:   }
                   4113:   else{
                   4114:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.214     brouard  4115: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   4116: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4117:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4118:   }
                   4119:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions by age at begin of transition </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
1.214     brouard  4120: 
1.226     brouard  4121:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4122:   j1=0;
1.126     brouard  4123:   
1.227     brouard  4124:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4125:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4126:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.220     brouard  4127: 
1.226     brouard  4128:   first=1;
1.220     brouard  4129: 
1.226     brouard  4130:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4131:      reference=low_education V1=0,V2=0
                   4132:      med_educ                V1=1 V2=0, 
                   4133:      high_educ               V1=0 V2=1
                   4134:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4135:   */
1.126     brouard  4136: 
1.227     brouard  4137:   for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives V4=0, V3=0 for example, fixed or varying covariates */
1.226     brouard  4138:     posproptt=0.;
                   4139:     /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4140:       scanf("%d", i);*/
                   4141:     for (i=-5; i<=nlstate+ndeath; i++)  
                   4142:       for (jk=-5; jk<=nlstate+ndeath; jk++)  
1.231     brouard  4143:                                for(m=iagemin; m <= iagemax+3; m++)
                   4144:                                        freq[i][jk][m]=0;
                   4145:                
1.226     brouard  4146:     for (i=1; i<=nlstate; i++)  {
                   4147:       for(m=iagemin; m <= iagemax+3; m++)
1.231     brouard  4148:                                prop[i][m]=0;
1.226     brouard  4149:       posprop[i]=0;
                   4150:       pospropt[i]=0;
                   4151:     }
1.227     brouard  4152:     /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4153:     /*   meanq[z1]+=0.; */
                   4154:     /*   for(m=1;m<=lastpass;m++){ */
                   4155:     /*         meanqt[m][z1]=0.; */
                   4156:     /*   } */
                   4157:     /* } */
1.231     brouard  4158:                
1.226     brouard  4159:     dateintsum=0;
                   4160:     k2cpt=0;
1.227     brouard  4161:     /* For that combination of covariate j1, we count and print the frequencies in one pass */
1.226     brouard  4162:     for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4163:       bool=1;
1.227     brouard  4164:       if(anyvaryingduminmodel==0){ /* If All fixed covariates */
1.234     brouard  4165:        if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
1.227     brouard  4166:          /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4167:          /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4168:          /* } */
1.234     brouard  4169:          for (z1=1; z1<=cptcoveff; z1++) {  
                   4170:            /* if(Tvaraff[z1] ==-20){ */
                   4171:            /*   /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4172:            /* }else  if(Tvaraff[z1] ==-10){ */
                   4173:            /*   /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4174:            /* }else  */
                   4175:            if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){
                   4176:              /* Tests if this individual iind responded to j1 (V4=1 V3=0) */
                   4177:              bool=0;
                   4178:              /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4179:                 bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4180:                 j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4181:              /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4182:            } /* Onlyf fixed */
                   4183:          } /* end z1 */
                   4184:        } /* cptcovn > 0 */
1.227     brouard  4185:       } /* end any */
                   4186:       if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
1.234     brouard  4187:        /* for(m=firstpass; m<=lastpass; m++){ */
                   4188:        for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4189:          m=mw[mi][iind];
                   4190:          if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4191:            for (z1=1; z1<=cptcoveff; z1++) {
                   4192:              if( Fixed[Tmodelind[z1]]==1){
                   4193:                iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4194:                if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4195:                  bool=0;
                   4196:              }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4197:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4198:                  bool=0;
                   4199:                }
                   4200:              }
                   4201:            }
                   4202:          }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4203:          /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4204:          if(bool==1){
                   4205:            /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4206:               and mw[mi+1][iind]. dh depends on stepm. */
                   4207:            agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4208:            ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4209:            if(m >=firstpass && m <=lastpass){
                   4210:              k2=anint[m][iind]+(mint[m][iind]/12.);
                   4211:              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4212:              if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4213:              if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4214:              if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4215:                prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4216:              if (m<lastpass) {
                   4217:                /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4218:                /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4219:                if(s[m][iind]==-1)
                   4220:                  printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4221:                freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4222:                /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4223:                freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
                   4224:              }
                   4225:            } /* end if between passes */  
                   4226:            if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99)) {
                   4227:              dateintsum=dateintsum+k2;
                   4228:              k2cpt++;
                   4229:              /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
                   4230:            }
                   4231:          } /* end bool 2 */
                   4232:        } /* end m */
1.226     brouard  4233:       } /* end bool */
                   4234:     } /* end iind = 1 to imx */
                   4235:     /* prop[s][age] is feeded for any initial and valid live state as well as
                   4236:        freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
1.231     brouard  4237:                
                   4238:                
1.226     brouard  4239:     /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4240:     pstamp(ficresp);
1.227     brouard  4241:     /* if  (ncoveff>0) { */
                   4242:     if  (cptcoveff>0) {
1.226     brouard  4243:       fprintf(ficresp, "\n#********** Variable "); 
                   4244:       fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4245:       fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
1.227     brouard  4246:       for (z1=1; z1<=cptcoveff; z1++){
1.234     brouard  4247:        fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4248:        fprintf(ficresphtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4249:        fprintf(ficresphtmfr, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.226     brouard  4250:       }
                   4251:       fprintf(ficresp, "**********\n#");
                   4252:       fprintf(ficresphtm, "**********</h3>\n");
                   4253:       fprintf(ficresphtmfr, "**********</h3>\n");
                   4254:       fprintf(ficlog, "\n#********** Variable "); 
1.227     brouard  4255:       for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.226     brouard  4256:       fprintf(ficlog, "**********\n");
                   4257:     }
                   4258:     fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4259:     for(i=1; i<=nlstate;i++) {
                   4260:       fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
                   4261:       fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4262:     }
                   4263:     fprintf(ficresp, "\n");
                   4264:     fprintf(ficresphtm, "\n");
1.231     brouard  4265:                
1.226     brouard  4266:     /* Header of frequency table by age */
                   4267:     fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4268:     fprintf(ficresphtmfr,"<th>Age</th> ");
                   4269:     for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4270:       for(m=-1; m <=nlstate+ndeath; m++){
1.234     brouard  4271:        if(jk!=0 && m!=0)
                   4272:          fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.226     brouard  4273:       }
                   4274:     }
                   4275:     fprintf(ficresphtmfr, "\n");
1.231     brouard  4276:                
1.226     brouard  4277:     /* For each age */
                   4278:     for(iage=iagemin; iage <= iagemax+3; iage++){
                   4279:       fprintf(ficresphtm,"<tr>");
                   4280:       if(iage==iagemax+1){
1.231     brouard  4281:                                fprintf(ficlog,"1");
                   4282:                                fprintf(ficresphtmfr,"<tr><th>0</th> ");
1.226     brouard  4283:       }else if(iage==iagemax+2){
1.231     brouard  4284:                                fprintf(ficlog,"0");
                   4285:                                fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
1.226     brouard  4286:       }else if(iage==iagemax+3){
1.231     brouard  4287:                                fprintf(ficlog,"Total");
                   4288:                                fprintf(ficresphtmfr,"<tr><th>Total</th> ");
1.226     brouard  4289:       }else{
1.231     brouard  4290:                                if(first==1){
                   4291:                                        first=0;
                   4292:                                        printf("See log file for details...\n");
                   4293:                                }
                   4294:                                fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4295:                                fprintf(ficlog,"Age %d", iage);
1.226     brouard  4296:       }
                   4297:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4298:                                for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4299:                                        pp[jk] += freq[jk][m][iage]; 
1.226     brouard  4300:       }
                   4301:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4302:                                for(m=-1, pos=0; m <=0 ; m++)
                   4303:                                        pos += freq[jk][m][iage];
                   4304:                                if(pp[jk]>=1.e-10){
                   4305:                                        if(first==1){
                   4306:                                                printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4307:                                        }
                   4308:                                        fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4309:                                }else{
                   4310:                                        if(first==1)
                   4311:                                                printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4312:                                        fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4313:                                }
1.226     brouard  4314:       }
1.231     brouard  4315:                        
1.226     brouard  4316:       for(jk=1; jk <=nlstate ; jk++){ 
1.231     brouard  4317:                                /* posprop[jk]=0; */
                   4318:                                for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4319:                                        pp[jk] += freq[jk][m][iage];
1.226     brouard  4320:       }        /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
1.231     brouard  4321:                        
1.226     brouard  4322:       for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
1.231     brouard  4323:                                pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4324:                                posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4325:                                                                                                                                                                        from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4326:                                pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4327:                                                                                                                                                                from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
1.226     brouard  4328:       }
                   4329:       for(jk=1; jk <=nlstate ; jk++){
1.231     brouard  4330:                                if(pos>=1.e-5){
                   4331:                                        if(first==1)
                   4332:                                                printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4333:                                        fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4334:                                }else{
                   4335:                                        if(first==1)
                   4336:                                                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4337:                                        fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4338:                                }
                   4339:                                if( iage <= iagemax){
                   4340:                                        if(pos>=1.e-5){
                   4341:                                                fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4342:                                                fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4343:                                                /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4344:                                                /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4345:                                        }
                   4346:                                        else{
                   4347:                                                fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4348:                                                fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4349:                                        }
                   4350:                                }
                   4351:                                pospropt[jk] +=posprop[jk];
1.226     brouard  4352:       } /* end loop jk */
                   4353:       /* pospropt=0.; */
                   4354:       for(jk=-1; jk <=nlstate+ndeath; jk++){
1.231     brouard  4355:                                for(m=-1; m <=nlstate+ndeath; m++){
                   4356:                                        if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4357:                                                if(first==1){
                   4358:                                                        printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4359:                                                }
                   4360:                                                fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4361:                                        }
                   4362:                                        if(jk!=0 && m!=0)
                   4363:                                                fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
                   4364:                                }
1.226     brouard  4365:       } /* end loop jk */
                   4366:       posproptt=0.; 
                   4367:       for(jk=1; jk <=nlstate; jk++){
1.231     brouard  4368:                                posproptt += pospropt[jk];
1.226     brouard  4369:       }
                   4370:       fprintf(ficresphtmfr,"</tr>\n ");
                   4371:       if(iage <= iagemax){
1.231     brouard  4372:                                fprintf(ficresp,"\n");
                   4373:                                fprintf(ficresphtm,"</tr>\n");
1.226     brouard  4374:       }
                   4375:       if(first==1)
1.231     brouard  4376:                                printf("Others in log...\n");
1.226     brouard  4377:       fprintf(ficlog,"\n");
                   4378:     } /* end loop age iage */
                   4379:     fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4380:     for(jk=1; jk <=nlstate ; jk++){
                   4381:       if(posproptt < 1.e-5){
1.231     brouard  4382:                                fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt);   
1.226     brouard  4383:       }else{
1.231     brouard  4384:                                fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);    
1.226     brouard  4385:       }
                   4386:     }
                   4387:     fprintf(ficresphtm,"</tr>\n");
                   4388:     fprintf(ficresphtm,"</table>\n");
                   4389:     fprintf(ficresphtmfr,"</table>\n");
                   4390:     if(posproptt < 1.e-5){
                   4391:       fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4392:       fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4393:       fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4394:       invalidvarcomb[j1]=1;
                   4395:     }else{
                   4396:       fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4397:       invalidvarcomb[j1]=0;
                   4398:     }
                   4399:     fprintf(ficresphtmfr,"</table>\n");
                   4400:   } /* end selected combination of covariate j1 */
                   4401:   dateintmean=dateintsum/k2cpt; 
1.231     brouard  4402:        
1.226     brouard  4403:   fclose(ficresp);
                   4404:   fclose(ficresphtm);
                   4405:   fclose(ficresphtmfr);
                   4406:   free_vector(meanq,1,nqfveff);
                   4407:   free_matrix(meanqt,1,lastpass,1,nqtveff);
                   4408:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4409:   free_vector(pospropt,1,nlstate);
                   4410:   free_vector(posprop,1,nlstate);
                   4411:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+3+AGEMARGE);
                   4412:   free_vector(pp,1,nlstate);
                   4413:   /* End of freqsummary */
                   4414: }
1.126     brouard  4415: 
                   4416: /************ Prevalence ********************/
1.227     brouard  4417: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4418: {  
                   4419:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4420:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4421:      We still use firstpass and lastpass as another selection.
                   4422:   */
1.126     brouard  4423:  
1.227     brouard  4424:   int i, m, jk, j1, bool, z1,j, iv;
                   4425:   int mi; /* Effective wave */
                   4426:   int iage;
                   4427:   double agebegin, ageend;
                   4428: 
                   4429:   double **prop;
                   4430:   double posprop; 
                   4431:   double  y2; /* in fractional years */
                   4432:   int iagemin, iagemax;
                   4433:   int first; /** to stop verbosity which is redirected to log file */
                   4434: 
                   4435:   iagemin= (int) agemin;
                   4436:   iagemax= (int) agemax;
                   4437:   /*pp=vector(1,nlstate);*/
                   4438:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+3+AGEMARGE); 
                   4439:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4440:   j1=0;
1.222     brouard  4441:   
1.227     brouard  4442:   /*j=cptcoveff;*/
                   4443:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4444:   
1.227     brouard  4445:   first=1;
                   4446:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4447:     for (i=1; i<=nlstate; i++)  
                   4448:       for(iage=iagemin-AGEMARGE; iage <= iagemax+3+AGEMARGE; iage++)
                   4449:        prop[i][iage]=0.0;
                   4450:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4451:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4452:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4453:     
                   4454:     for (i=1; i<=imx; i++) { /* Each individual */
                   4455:       bool=1;
                   4456:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4457:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4458:        m=mw[mi][i];
                   4459:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4460:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4461:        for (z1=1; z1<=cptcoveff; z1++){
                   4462:          if( Fixed[Tmodelind[z1]]==1){
                   4463:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4464:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4465:              bool=0;
                   4466:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4467:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4468:              bool=0;
                   4469:            }
                   4470:        }
                   4471:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4472:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4473:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4474:          if(m >=firstpass && m <=lastpass){
                   4475:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4476:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4477:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4478:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
                   4479:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+3+AGEMARGE){
                   4480:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4481:                exit(1);
                   4482:              }
                   4483:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4484:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4485:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4486:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4487:              } /* end valid statuses */ 
                   4488:            } /* end selection of dates */
                   4489:          } /* end selection of waves */
                   4490:        } /* end bool */
                   4491:       } /* end wave */
                   4492:     } /* end individual */
                   4493:     for(i=iagemin; i <= iagemax+3; i++){  
                   4494:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4495:        posprop += prop[jk][i]; 
                   4496:       } 
                   4497:       
                   4498:       for(jk=1; jk <=nlstate ; jk++){      
                   4499:        if( i <=  iagemax){ 
                   4500:          if(posprop>=1.e-5){ 
                   4501:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4502:          } else{
                   4503:            if(first==1){
                   4504:              first=0;
                   4505:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4506:            }
                   4507:          }
                   4508:        } 
                   4509:       }/* end jk */ 
                   4510:     }/* end i */ 
1.222     brouard  4511:      /*} *//* end i1 */
1.227     brouard  4512:   } /* end j1 */
1.222     brouard  4513:   
1.227     brouard  4514:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4515:   /*free_vector(pp,1,nlstate);*/
                   4516:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+3+AGEMARGE);
                   4517: }  /* End of prevalence */
1.126     brouard  4518: 
                   4519: /************* Waves Concatenation ***************/
                   4520: 
                   4521: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4522: {
                   4523:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4524:      Death is a valid wave (if date is known).
                   4525:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4526:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4527:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4528:   */
1.126     brouard  4529: 
1.224     brouard  4530:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4531:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4532:      double sum=0., jmean=0.;*/
1.224     brouard  4533:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4534:   int j, k=0,jk, ju, jl;
                   4535:   double sum=0.;
                   4536:   first=0;
1.214     brouard  4537:   firstwo=0;
1.217     brouard  4538:   firsthree=0;
1.218     brouard  4539:   firstfour=0;
1.164     brouard  4540:   jmin=100000;
1.126     brouard  4541:   jmax=-1;
                   4542:   jmean=0.;
1.224     brouard  4543: 
                   4544: /* Treating live states */
1.214     brouard  4545:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4546:     mi=0;  /* First valid wave */
1.227     brouard  4547:     mli=0; /* Last valid wave */
1.126     brouard  4548:     m=firstpass;
1.214     brouard  4549:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4550:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4551:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4552:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4553:        mw[++mi][i]=m;
                   4554:        mli=m;
1.224     brouard  4555:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4556:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4557:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4558:       }
1.227     brouard  4559:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4560: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4561:        break;
1.224     brouard  4562: #else
1.227     brouard  4563:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4564:          if(firsthree == 0){
                   4565:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4566:            firsthree=1;
                   4567:          }
                   4568:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4569:          mw[++mi][i]=m;
                   4570:          mli=m;
                   4571:        }
                   4572:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4573:          nbwarn++;
                   4574:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4575:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4576:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4577:          }
                   4578:          break;
                   4579:        }
                   4580:        break;
1.224     brouard  4581: #endif
1.227     brouard  4582:       }/* End m >= lastpass */
1.126     brouard  4583:     }/* end while */
1.224     brouard  4584: 
1.227     brouard  4585:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4586:     /* After last pass */
1.224     brouard  4587: /* Treating death states */
1.214     brouard  4588:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4589:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4590:       /* } */
1.126     brouard  4591:       mi++;    /* Death is another wave */
                   4592:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4593:       /* Only death is a correct wave */
1.126     brouard  4594:       mw[mi][i]=m;
1.224     brouard  4595:     }
                   4596: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.227     brouard  4597:     else if ((int) andc[i] != 9999) { /* Status is negative. A death occured after lastpass, we can't take it into account because of potential bias */
1.216     brouard  4598:       /* m++; */
                   4599:       /* mi++; */
                   4600:       /* s[m][i]=nlstate+1;  /\* We are setting the status to the last of non live state *\/ */
                   4601:       /* mw[mi][i]=m; */
1.218     brouard  4602:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4603:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4604:          nbwarn++;
                   4605:          if(firstfiv==0){
                   4606:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4607:            firstfiv=1;
                   4608:          }else{
                   4609:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4610:          }
                   4611:        }else{ /* Death occured afer last wave potential bias */
                   4612:          nberr++;
                   4613:          if(firstwo==0){
                   4614:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4615:            firstwo=1;
                   4616:          }
                   4617:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4618:        }
1.218     brouard  4619:       }else{ /* end date of interview is known */
1.227     brouard  4620:        /* death is known but not confirmed by death status at any wave */
                   4621:        if(firstfour==0){
                   4622:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4623:          firstfour=1;
                   4624:        }
                   4625:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4626:       }
1.224     brouard  4627:     } /* end if date of death is known */
                   4628: #endif
                   4629:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4630:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4631:     if(mi==0){
                   4632:       nbwarn++;
                   4633:       if(first==0){
1.227     brouard  4634:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   4635:        first=1;
1.126     brouard  4636:       }
                   4637:       if(first==1){
1.227     brouard  4638:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  4639:       }
                   4640:     } /* end mi==0 */
                   4641:   } /* End individuals */
1.214     brouard  4642:   /* wav and mw are no more changed */
1.223     brouard  4643:        
1.214     brouard  4644:   
1.126     brouard  4645:   for(i=1; i<=imx; i++){
                   4646:     for(mi=1; mi<wav[i];mi++){
                   4647:       if (stepm <=0)
1.227     brouard  4648:        dh[mi][i]=1;
1.126     brouard  4649:       else{
1.227     brouard  4650:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   4651:          if (agedc[i] < 2*AGESUP) {
                   4652:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   4653:            if(j==0) j=1;  /* Survives at least one month after exam */
                   4654:            else if(j<0){
                   4655:              nberr++;
                   4656:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4657:              j=1; /* Temporary Dangerous patch */
                   4658:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4659:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4660:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   4661:            }
                   4662:            k=k+1;
                   4663:            if (j >= jmax){
                   4664:              jmax=j;
                   4665:              ijmax=i;
                   4666:            }
                   4667:            if (j <= jmin){
                   4668:              jmin=j;
                   4669:              ijmin=i;
                   4670:            }
                   4671:            sum=sum+j;
                   4672:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   4673:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   4674:          }
                   4675:        }
                   4676:        else{
                   4677:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  4678: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  4679:                                        
1.227     brouard  4680:          k=k+1;
                   4681:          if (j >= jmax) {
                   4682:            jmax=j;
                   4683:            ijmax=i;
                   4684:          }
                   4685:          else if (j <= jmin){
                   4686:            jmin=j;
                   4687:            ijmin=i;
                   4688:          }
                   4689:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   4690:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   4691:          if(j<0){
                   4692:            nberr++;
                   4693:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4694:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   4695:          }
                   4696:          sum=sum+j;
                   4697:        }
                   4698:        jk= j/stepm;
                   4699:        jl= j -jk*stepm;
                   4700:        ju= j -(jk+1)*stepm;
                   4701:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   4702:          if(jl==0){
                   4703:            dh[mi][i]=jk;
                   4704:            bh[mi][i]=0;
                   4705:          }else{ /* We want a negative bias in order to only have interpolation ie
                   4706:                  * to avoid the price of an extra matrix product in likelihood */
                   4707:            dh[mi][i]=jk+1;
                   4708:            bh[mi][i]=ju;
                   4709:          }
                   4710:        }else{
                   4711:          if(jl <= -ju){
                   4712:            dh[mi][i]=jk;
                   4713:            bh[mi][i]=jl;       /* bias is positive if real duration
                   4714:                                 * is higher than the multiple of stepm and negative otherwise.
                   4715:                                 */
                   4716:          }
                   4717:          else{
                   4718:            dh[mi][i]=jk+1;
                   4719:            bh[mi][i]=ju;
                   4720:          }
                   4721:          if(dh[mi][i]==0){
                   4722:            dh[mi][i]=1; /* At least one step */
                   4723:            bh[mi][i]=ju; /* At least one step */
                   4724:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   4725:          }
                   4726:        } /* end if mle */
1.126     brouard  4727:       }
                   4728:     } /* end wave */
                   4729:   }
                   4730:   jmean=sum/k;
                   4731:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  4732:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  4733: }
1.126     brouard  4734: 
                   4735: /*********** Tricode ****************************/
1.220     brouard  4736:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.126     brouard  4737: {
1.144     brouard  4738:   /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   4739:   /*     Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
1.169     brouard  4740:    * Boring subroutine which should only output nbcode[Tvar[j]][k]
1.224     brouard  4741:    * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   4742:    * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
1.144     brouard  4743:   */
1.130     brouard  4744: 
1.145     brouard  4745:   int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
1.136     brouard  4746:   int modmaxcovj=0; /* Modality max of covariates j */
1.145     brouard  4747:   int cptcode=0; /* Modality max of covariates j */
                   4748:   int modmincovj=0; /* Modality min of covariates j */
                   4749: 
                   4750: 
1.220     brouard  4751:   /* cptcoveff=0;  */
1.224     brouard  4752:        /* *cptcov=0; */
1.126     brouard  4753:  
1.144     brouard  4754:   for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  4755: 
1.224     brouard  4756:   /* Loop on covariates without age and products and no quantitative variable */
                   4757:   /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
1.227     brouard  4758:   for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   4759:     for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   4760:     if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   4761:       switch(Fixed[k]) {
                   4762:       case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.231     brouard  4763:                                for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   4764:                                        ij=(int)(covar[Tvar[k]][i]);
                   4765:                                        /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   4766:                                         * If product of Vn*Vm, still boolean *:
                   4767:                                         * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   4768:                                         * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   4769:                                        /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   4770:                                                 modality of the nth covariate of individual i. */
                   4771:                                        if (ij > modmaxcovj)
                   4772:                                                modmaxcovj=ij; 
                   4773:                                        else if (ij < modmincovj) 
                   4774:                                                modmincovj=ij; 
                   4775:                                        if ((ij < -1) && (ij > NCOVMAX)){
                   4776:                                                printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   4777:                                                exit(1);
                   4778:                                        }else
                   4779:                                                Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   4780:                                        /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   4781:                                        /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   4782:                                        /* getting the maximum value of the modality of the covariate
                   4783:                                                 (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   4784:                                                 female ies 1, then modmaxcovj=1.
                   4785:                                        */
                   4786:                                } /* end for loop on individuals i */
                   4787:                                printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4788:                                fprintf(ficlog," Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   4789:                                cptcode=modmaxcovj;
                   4790:                                /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   4791:                                /*for (i=0; i<=cptcode; i++) {*/
                   4792:                                for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   4793:                                        printf("Frequencies of covariates %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4794:                                        fprintf(ficlog, "Frequencies of covariates %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   4795:                                        if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   4796:                                                if( j != -1){
                   4797:                                                        ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   4798:                                                                                                                                 covariate for which somebody answered excluding 
                   4799:                                                                                                                                 undefined. Usually 2: 0 and 1. */
                   4800:                                                }
                   4801:                                                ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   4802:                                                                                                                                                covariate for which somebody answered including 
                   4803:                                                                                                                                                undefined. Usually 3: -1, 0 and 1. */
                   4804:                                        }       /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   4805:                                                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   4806:                                } /* Ndum[-1] number of undefined modalities */
                   4807:                        
                   4808:                                /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   4809:                                /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   4810:                                /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   4811:                                /* modmincovj=3; modmaxcovj = 7; */
                   4812:                                /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   4813:                                /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   4814:                          /*             defining two dummy variables: variables V1_1 and V1_2.*/
                   4815:              /* nbcode[Tvar[j]][ij]=k; */
                   4816:              /* nbcode[Tvar[j]][1]=0; */
                   4817:              /* nbcode[Tvar[j]][2]=1; */
                   4818:              /* nbcode[Tvar[j]][3]=2; */
                   4819:              /* To be continued (not working yet). */
                   4820:              ij=0; /* ij is similar to i but can jump over null modalities */
                   4821:                                for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   4822:          if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   4823:                  break;
                   4824:                }
                   4825:                                        ij++;
                   4826:                                        nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   4827:                                        cptcode = ij; /* New max modality for covar j */
                   4828:                                } /* end of loop on modality i=-1 to 1 or more */
                   4829:                                break;
1.227     brouard  4830:       case 1: /* Testing on varying covariate, could be simple and
                   4831:               * should look at waves or product of fixed *
                   4832:               * varying. No time to test -1, assuming 0 and 1 only */
1.231     brouard  4833:                                ij=0;
                   4834:                                for(i=0; i<=1;i++){
                   4835:                                        nbcode[Tvar[k]][++ij]=i;
                   4836:                                }
                   4837:                                break;
1.227     brouard  4838:       default:
1.231     brouard  4839:                                break;
1.227     brouard  4840:       } /* end switch */
                   4841:     } /* end dummy test */
1.225     brouard  4842:     
1.192     brouard  4843:     /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   4844:     /*         /\*recode from 0 *\/ */
                   4845:     /*                                      k is a modality. If we have model=V1+V1*sex  */
                   4846:     /*                                      then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   4847:     /*                                   But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   4848:     /*         } */
                   4849:     /*         /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   4850:     /*         if (ij > ncodemax[j]) { */
                   4851:     /*           printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   4852:     /*           fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   4853:     /*           break; */
                   4854:     /*         } */
                   4855:     /*   }  /\* end of loop on modality k *\/ */
1.137     brouard  4856:   } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   4857:   
1.225     brouard  4858:   for (k=-1; k< maxncov; k++) Ndum[k]=0; 
1.227     brouard  4859:   /* Look at fixed dummy (single or product) covariates to check empty modalities */
1.187     brouard  4860:   for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
1.225     brouard  4861:     /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
1.227     brouard  4862:     ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   4863:     Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   4864:     /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
1.225     brouard  4865:   } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   4866:   
                   4867:   ij=0;
1.227     brouard  4868:   /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   4869:   for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
1.225     brouard  4870:     /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
1.227     brouard  4871:     /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   4872:     if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   4873:       /* If product not in single variable we don't print results */
1.225     brouard  4874:       /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
1.230     brouard  4875:       ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   4876:       Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   4877:       Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
1.231     brouard  4878:       TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
1.227     brouard  4879:       if(Fixed[k]!=0)
                   4880:         anyvaryingduminmodel=1;
1.231     brouard  4881:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   4882:                        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   4883:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   4884:                        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   4885:                        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   4886:                        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
1.227     brouard  4887:     } 
1.225     brouard  4888:   } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   4889:   /* ij--; */
                   4890:   /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   4891:   *cptcov=ij; /*Number of total real effective covariates: effective
1.231     brouard  4892:                                                         * because they can be excluded from the model and real
                   4893:                                                         * if in the model but excluded because missing values, but how to get k from ij?*/
1.227     brouard  4894:   for(j=ij+1; j<= cptcovt; j++){
                   4895:     Tvaraff[j]=0;
                   4896:     Tmodelind[j]=0;
                   4897:   }
1.228     brouard  4898:   for(j=ntveff+1; j<= cptcovt; j++){
                   4899:     TmodelInvind[j]=0;
                   4900:   }
1.227     brouard  4901:   /* To be sorted */
                   4902:   ;
1.126     brouard  4903: }
                   4904: 
1.145     brouard  4905: 
1.126     brouard  4906: /*********** Health Expectancies ****************/
                   4907: 
1.235     brouard  4908:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  4909: 
                   4910: {
                   4911:   /* Health expectancies, no variances */
1.164     brouard  4912:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  4913:   int nhstepma, nstepma; /* Decreasing with age */
                   4914:   double age, agelim, hf;
                   4915:   double ***p3mat;
                   4916:   double eip;
                   4917: 
                   4918:   pstamp(ficreseij);
                   4919:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   4920:   fprintf(ficreseij,"# Age");
                   4921:   for(i=1; i<=nlstate;i++){
                   4922:     for(j=1; j<=nlstate;j++){
                   4923:       fprintf(ficreseij," e%1d%1d ",i,j);
                   4924:     }
                   4925:     fprintf(ficreseij," e%1d. ",i);
                   4926:   }
                   4927:   fprintf(ficreseij,"\n");
                   4928: 
                   4929:   
                   4930:   if(estepm < stepm){
                   4931:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   4932:   }
                   4933:   else  hstepm=estepm;   
                   4934:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   4935:    * This is mainly to measure the difference between two models: for example
                   4936:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   4937:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   4938:    * progression in between and thus overestimating or underestimating according
                   4939:    * to the curvature of the survival function. If, for the same date, we 
                   4940:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   4941:    * to compare the new estimate of Life expectancy with the same linear 
                   4942:    * hypothesis. A more precise result, taking into account a more precise
                   4943:    * curvature will be obtained if estepm is as small as stepm. */
                   4944: 
                   4945:   /* For example we decided to compute the life expectancy with the smallest unit */
                   4946:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   4947:      nhstepm is the number of hstepm from age to agelim 
                   4948:      nstepm is the number of stepm from age to agelin. 
                   4949:      Look at hpijx to understand the reason of that which relies in memory size
                   4950:      and note for a fixed period like estepm months */
                   4951:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   4952:      survival function given by stepm (the optimization length). Unfortunately it
                   4953:      means that if the survival funtion is printed only each two years of age and if
                   4954:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   4955:      results. So we changed our mind and took the option of the best precision.
                   4956:   */
                   4957:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   4958: 
                   4959:   agelim=AGESUP;
                   4960:   /* If stepm=6 months */
                   4961:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   4962:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   4963:     
                   4964: /* nhstepm age range expressed in number of stepm */
                   4965:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   4966:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4967:   /* if (stepm >= YEARM) hstepm=1;*/
                   4968:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   4969:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   4970: 
                   4971:   for (age=bage; age<=fage; age ++){ 
                   4972:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   4973:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   4974:     /* if (stepm >= YEARM) hstepm=1;*/
                   4975:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   4976: 
                   4977:     /* If stepm=6 months */
                   4978:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   4979:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   4980:     
1.235     brouard  4981:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  4982:     
                   4983:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   4984:     
                   4985:     printf("%d|",(int)age);fflush(stdout);
                   4986:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   4987:     
                   4988:     /* Computing expectancies */
                   4989:     for(i=1; i<=nlstate;i++)
                   4990:       for(j=1; j<=nlstate;j++)
                   4991:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   4992:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   4993:          
                   4994:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   4995: 
                   4996:        }
                   4997: 
                   4998:     fprintf(ficreseij,"%3.0f",age );
                   4999:     for(i=1; i<=nlstate;i++){
                   5000:       eip=0;
                   5001:       for(j=1; j<=nlstate;j++){
                   5002:        eip +=eij[i][j][(int)age];
                   5003:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5004:       }
                   5005:       fprintf(ficreseij,"%9.4f", eip );
                   5006:     }
                   5007:     fprintf(ficreseij,"\n");
                   5008:     
                   5009:   }
                   5010:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5011:   printf("\n");
                   5012:   fprintf(ficlog,"\n");
                   5013:   
                   5014: }
                   5015: 
1.235     brouard  5016:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5017: 
                   5018: {
                   5019:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5020:      to initial status i, ei. .
1.126     brouard  5021:   */
                   5022:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5023:   int nhstepma, nstepma; /* Decreasing with age */
                   5024:   double age, agelim, hf;
                   5025:   double ***p3matp, ***p3matm, ***varhe;
                   5026:   double **dnewm,**doldm;
                   5027:   double *xp, *xm;
                   5028:   double **gp, **gm;
                   5029:   double ***gradg, ***trgradg;
                   5030:   int theta;
                   5031: 
                   5032:   double eip, vip;
                   5033: 
                   5034:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5035:   xp=vector(1,npar);
                   5036:   xm=vector(1,npar);
                   5037:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5038:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5039:   
                   5040:   pstamp(ficresstdeij);
                   5041:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5042:   fprintf(ficresstdeij,"# Age");
                   5043:   for(i=1; i<=nlstate;i++){
                   5044:     for(j=1; j<=nlstate;j++)
                   5045:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5046:     fprintf(ficresstdeij," e%1d. ",i);
                   5047:   }
                   5048:   fprintf(ficresstdeij,"\n");
                   5049: 
                   5050:   pstamp(ficrescveij);
                   5051:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5052:   fprintf(ficrescveij,"# Age");
                   5053:   for(i=1; i<=nlstate;i++)
                   5054:     for(j=1; j<=nlstate;j++){
                   5055:       cptj= (j-1)*nlstate+i;
                   5056:       for(i2=1; i2<=nlstate;i2++)
                   5057:        for(j2=1; j2<=nlstate;j2++){
                   5058:          cptj2= (j2-1)*nlstate+i2;
                   5059:          if(cptj2 <= cptj)
                   5060:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5061:        }
                   5062:     }
                   5063:   fprintf(ficrescveij,"\n");
                   5064:   
                   5065:   if(estepm < stepm){
                   5066:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5067:   }
                   5068:   else  hstepm=estepm;   
                   5069:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5070:    * This is mainly to measure the difference between two models: for example
                   5071:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5072:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5073:    * progression in between and thus overestimating or underestimating according
                   5074:    * to the curvature of the survival function. If, for the same date, we 
                   5075:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5076:    * to compare the new estimate of Life expectancy with the same linear 
                   5077:    * hypothesis. A more precise result, taking into account a more precise
                   5078:    * curvature will be obtained if estepm is as small as stepm. */
                   5079: 
                   5080:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5081:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5082:      nhstepm is the number of hstepm from age to agelim 
                   5083:      nstepm is the number of stepm from age to agelin. 
                   5084:      Look at hpijx to understand the reason of that which relies in memory size
                   5085:      and note for a fixed period like estepm months */
                   5086:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5087:      survival function given by stepm (the optimization length). Unfortunately it
                   5088:      means that if the survival funtion is printed only each two years of age and if
                   5089:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5090:      results. So we changed our mind and took the option of the best precision.
                   5091:   */
                   5092:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5093: 
                   5094:   /* If stepm=6 months */
                   5095:   /* nhstepm age range expressed in number of stepm */
                   5096:   agelim=AGESUP;
                   5097:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5098:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5099:   /* if (stepm >= YEARM) hstepm=1;*/
                   5100:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5101:   
                   5102:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5103:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5104:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5105:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5106:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5107:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5108: 
                   5109:   for (age=bage; age<=fage; age ++){ 
                   5110:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5111:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5112:     /* if (stepm >= YEARM) hstepm=1;*/
                   5113:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5114:                
1.126     brouard  5115:     /* If stepm=6 months */
                   5116:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5117:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5118:     
                   5119:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5120:                
1.126     brouard  5121:     /* Computing  Variances of health expectancies */
                   5122:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5123:        decrease memory allocation */
                   5124:     for(theta=1; theta <=npar; theta++){
                   5125:       for(i=1; i<=npar; i++){ 
1.222     brouard  5126:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5127:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5128:       }
1.235     brouard  5129:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5130:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5131:                        
1.126     brouard  5132:       for(j=1; j<= nlstate; j++){
1.222     brouard  5133:        for(i=1; i<=nlstate; i++){
                   5134:          for(h=0; h<=nhstepm-1; h++){
                   5135:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5136:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5137:          }
                   5138:        }
1.126     brouard  5139:       }
1.218     brouard  5140:                        
1.126     brouard  5141:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5142:        for(h=0; h<=nhstepm-1; h++){
                   5143:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5144:        }
1.126     brouard  5145:     }/* End theta */
                   5146:     
                   5147:     
                   5148:     for(h=0; h<=nhstepm-1; h++)
                   5149:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5150:        for(theta=1; theta <=npar; theta++)
                   5151:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5152:     
1.218     brouard  5153:                
1.222     brouard  5154:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5155:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5156:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5157:                
1.222     brouard  5158:     printf("%d|",(int)age);fflush(stdout);
                   5159:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5160:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5161:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5162:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5163:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5164:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5165:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5166:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5167:       }
                   5168:     }
1.218     brouard  5169:                
1.126     brouard  5170:     /* Computing expectancies */
1.235     brouard  5171:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5172:     for(i=1; i<=nlstate;i++)
                   5173:       for(j=1; j<=nlstate;j++)
1.222     brouard  5174:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5175:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5176:                                        
1.222     brouard  5177:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5178:                                        
1.222     brouard  5179:        }
1.218     brouard  5180:                
1.126     brouard  5181:     fprintf(ficresstdeij,"%3.0f",age );
                   5182:     for(i=1; i<=nlstate;i++){
                   5183:       eip=0.;
                   5184:       vip=0.;
                   5185:       for(j=1; j<=nlstate;j++){
1.222     brouard  5186:        eip += eij[i][j][(int)age];
                   5187:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5188:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5189:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5190:       }
                   5191:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5192:     }
                   5193:     fprintf(ficresstdeij,"\n");
1.218     brouard  5194:                
1.126     brouard  5195:     fprintf(ficrescveij,"%3.0f",age );
                   5196:     for(i=1; i<=nlstate;i++)
                   5197:       for(j=1; j<=nlstate;j++){
1.222     brouard  5198:        cptj= (j-1)*nlstate+i;
                   5199:        for(i2=1; i2<=nlstate;i2++)
                   5200:          for(j2=1; j2<=nlstate;j2++){
                   5201:            cptj2= (j2-1)*nlstate+i2;
                   5202:            if(cptj2 <= cptj)
                   5203:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5204:          }
1.126     brouard  5205:       }
                   5206:     fprintf(ficrescveij,"\n");
1.218     brouard  5207:                
1.126     brouard  5208:   }
                   5209:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5210:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5211:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5212:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5213:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5214:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5215:   printf("\n");
                   5216:   fprintf(ficlog,"\n");
1.218     brouard  5217:        
1.126     brouard  5218:   free_vector(xm,1,npar);
                   5219:   free_vector(xp,1,npar);
                   5220:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5221:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5222:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5223: }
1.218     brouard  5224:  
1.126     brouard  5225: /************ Variance ******************/
1.235     brouard  5226:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5227:  {
                   5228:    /* Variance of health expectancies */
                   5229:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5230:    /* double **newm;*/
                   5231:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5232:   
                   5233:    /* int movingaverage(); */
                   5234:    double **dnewm,**doldm;
                   5235:    double **dnewmp,**doldmp;
                   5236:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5237:    int k;
                   5238:    double *xp;
                   5239:    double **gp, **gm;  /* for var eij */
                   5240:    double ***gradg, ***trgradg; /*for var eij */
                   5241:    double **gradgp, **trgradgp; /* for var p point j */
                   5242:    double *gpp, *gmp; /* for var p point j */
                   5243:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5244:    double ***p3mat;
                   5245:    double age,agelim, hf;
                   5246:    /* double ***mobaverage; */
                   5247:    int theta;
                   5248:    char digit[4];
                   5249:    char digitp[25];
                   5250: 
                   5251:    char fileresprobmorprev[FILENAMELENGTH];
                   5252: 
                   5253:    if(popbased==1){
                   5254:      if(mobilav!=0)
                   5255:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5256:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5257:    }
                   5258:    else 
                   5259:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5260: 
1.218     brouard  5261:    /* if (mobilav!=0) { */
                   5262:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5263:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5264:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5265:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5266:    /*   } */
                   5267:    /* } */
                   5268: 
                   5269:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5270:    sprintf(digit,"%-d",ij);
                   5271:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5272:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5273:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5274:    strcat(fileresprobmorprev,fileresu);
                   5275:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5276:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5277:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5278:    }
                   5279:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5280:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5281:    pstamp(ficresprobmorprev);
                   5282:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
                   5283:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5284:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5285:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5286:      for(i=1; i<=nlstate;i++)
                   5287:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5288:    }  
                   5289:    fprintf(ficresprobmorprev,"\n");
                   5290:   
                   5291:    fprintf(ficgp,"\n# Routine varevsij");
                   5292:    fprintf(ficgp,"\nunset title \n");
                   5293:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5294:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5295:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5296:    /*   } */
                   5297:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5298:    pstamp(ficresvij);
                   5299:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5300:    if(popbased==1)
                   5301:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5302:    else
                   5303:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5304:    fprintf(ficresvij,"# Age");
                   5305:    for(i=1; i<=nlstate;i++)
                   5306:      for(j=1; j<=nlstate;j++)
                   5307:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5308:    fprintf(ficresvij,"\n");
                   5309: 
                   5310:    xp=vector(1,npar);
                   5311:    dnewm=matrix(1,nlstate,1,npar);
                   5312:    doldm=matrix(1,nlstate,1,nlstate);
                   5313:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5314:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5315: 
                   5316:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5317:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5318:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5319:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5320:   
1.218     brouard  5321:    if(estepm < stepm){
                   5322:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5323:    }
                   5324:    else  hstepm=estepm;   
                   5325:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5326:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5327:       nhstepm is the number of hstepm from age to agelim 
                   5328:       nstepm is the number of stepm from age to agelim. 
                   5329:       Look at function hpijx to understand why because of memory size limitations, 
                   5330:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5331:       survival function given by stepm (the optimization length). Unfortunately it
                   5332:       means that if the survival funtion is printed every two years of age and if
                   5333:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5334:       results. So we changed our mind and took the option of the best precision.
                   5335:    */
                   5336:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5337:    agelim = AGESUP;
                   5338:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5339:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5340:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5341:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5342:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5343:      gp=matrix(0,nhstepm,1,nlstate);
                   5344:      gm=matrix(0,nhstepm,1,nlstate);
                   5345:                
                   5346:                
                   5347:      for(theta=1; theta <=npar; theta++){
                   5348:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5349:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5350:        }
                   5351:                        
1.235     brouard  5352:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nresult);
1.218     brouard  5353:                        
                   5354:        if (popbased==1) {
                   5355:         if(mobilav ==0){
                   5356:           for(i=1; i<=nlstate;i++)
                   5357:             prlim[i][i]=probs[(int)age][i][ij];
                   5358:         }else{ /* mobilav */ 
                   5359:           for(i=1; i<=nlstate;i++)
                   5360:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5361:         }
                   5362:        }
                   5363:                        
1.235     brouard  5364:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5365:        for(j=1; j<= nlstate; j++){
                   5366:         for(h=0; h<=nhstepm; h++){
                   5367:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5368:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5369:         }
                   5370:        }
                   5371:        /* Next for computing probability of death (h=1 means
                   5372:          computed over hstepm matrices product = hstepm*stepm months) 
                   5373:          as a weighted average of prlim.
                   5374:        */
                   5375:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5376:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5377:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5378:        }    
                   5379:        /* end probability of death */
                   5380:                        
                   5381:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5382:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5383:                        
1.235     brouard  5384:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nresult);
1.218     brouard  5385:                        
                   5386:        if (popbased==1) {
                   5387:         if(mobilav ==0){
                   5388:           for(i=1; i<=nlstate;i++)
                   5389:             prlim[i][i]=probs[(int)age][i][ij];
                   5390:         }else{ /* mobilav */ 
                   5391:           for(i=1; i<=nlstate;i++)
                   5392:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5393:         }
                   5394:        }
                   5395:                        
1.235     brouard  5396:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5397:                        
                   5398:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5399:         for(h=0; h<=nhstepm; h++){
                   5400:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5401:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5402:         }
                   5403:        }
                   5404:        /* This for computing probability of death (h=1 means
                   5405:          computed over hstepm matrices product = hstepm*stepm months) 
                   5406:          as a weighted average of prlim.
                   5407:        */
                   5408:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5409:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5410:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5411:        }    
                   5412:        /* end probability of death */
                   5413:                        
                   5414:        for(j=1; j<= nlstate; j++) /* vareij */
                   5415:         for(h=0; h<=nhstepm; h++){
                   5416:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5417:         }
                   5418:                        
                   5419:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5420:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5421:        }
                   5422:                        
                   5423:      } /* End theta */
                   5424:                
                   5425:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5426:                
                   5427:      for(h=0; h<=nhstepm; h++) /* veij */
                   5428:        for(j=1; j<=nlstate;j++)
                   5429:         for(theta=1; theta <=npar; theta++)
                   5430:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5431:                
                   5432:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5433:        for(theta=1; theta <=npar; theta++)
                   5434:         trgradgp[j][theta]=gradgp[theta][j];
                   5435:                
                   5436:                
                   5437:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5438:      for(i=1;i<=nlstate;i++)
                   5439:        for(j=1;j<=nlstate;j++)
                   5440:         vareij[i][j][(int)age] =0.;
                   5441:                
                   5442:      for(h=0;h<=nhstepm;h++){
                   5443:        for(k=0;k<=nhstepm;k++){
                   5444:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5445:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5446:         for(i=1;i<=nlstate;i++)
                   5447:           for(j=1;j<=nlstate;j++)
                   5448:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5449:        }
                   5450:      }
                   5451:                
                   5452:      /* pptj */
                   5453:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5454:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5455:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5456:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5457:         varppt[j][i]=doldmp[j][i];
                   5458:      /* end ppptj */
                   5459:      /*  x centered again */
                   5460:                
1.235     brouard  5461:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nresult);
1.218     brouard  5462:                
                   5463:      if (popbased==1) {
                   5464:        if(mobilav ==0){
                   5465:         for(i=1; i<=nlstate;i++)
                   5466:           prlim[i][i]=probs[(int)age][i][ij];
                   5467:        }else{ /* mobilav */ 
                   5468:         for(i=1; i<=nlstate;i++)
                   5469:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5470:        }
                   5471:      }
                   5472:                
                   5473:      /* This for computing probability of death (h=1 means
                   5474:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5475:        as a weighted average of prlim.
                   5476:      */
1.235     brouard  5477:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5478:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5479:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5480:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5481:      }    
                   5482:      /* end probability of death */
                   5483:                
                   5484:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5485:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5486:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5487:        for(i=1; i<=nlstate;i++){
                   5488:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5489:        }
                   5490:      } 
                   5491:      fprintf(ficresprobmorprev,"\n");
                   5492:                
                   5493:      fprintf(ficresvij,"%.0f ",age );
                   5494:      for(i=1; i<=nlstate;i++)
                   5495:        for(j=1; j<=nlstate;j++){
                   5496:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5497:        }
                   5498:      fprintf(ficresvij,"\n");
                   5499:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5500:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5501:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5502:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5503:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5504:    } /* End age */
                   5505:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5506:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5507:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5508:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5509:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5510:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5511:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5512:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5513:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5514:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5515:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5516:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5517:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5518:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5519:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5520:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5521:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5522:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5523:     */
1.218     brouard  5524:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5525:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5526: 
1.218     brouard  5527:    free_vector(xp,1,npar);
                   5528:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5529:    free_matrix(dnewm,1,nlstate,1,npar);
                   5530:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5531:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5532:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5533:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5534:    fclose(ficresprobmorprev);
                   5535:    fflush(ficgp);
                   5536:    fflush(fichtm); 
                   5537:  }  /* end varevsij */
1.126     brouard  5538: 
                   5539: /************ Variance of prevlim ******************/
1.235     brouard  5540:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5541: {
1.205     brouard  5542:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5543:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5544: 
1.126     brouard  5545:   double **dnewm,**doldm;
                   5546:   int i, j, nhstepm, hstepm;
                   5547:   double *xp;
                   5548:   double *gp, *gm;
                   5549:   double **gradg, **trgradg;
1.208     brouard  5550:   double **mgm, **mgp;
1.126     brouard  5551:   double age,agelim;
                   5552:   int theta;
                   5553:   
                   5554:   pstamp(ficresvpl);
                   5555:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
                   5556:   fprintf(ficresvpl,"# Age");
                   5557:   for(i=1; i<=nlstate;i++)
                   5558:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5559:   fprintf(ficresvpl,"\n");
                   5560: 
                   5561:   xp=vector(1,npar);
                   5562:   dnewm=matrix(1,nlstate,1,npar);
                   5563:   doldm=matrix(1,nlstate,1,nlstate);
                   5564:   
                   5565:   hstepm=1*YEARM; /* Every year of age */
                   5566:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5567:   agelim = AGESUP;
                   5568:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5569:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5570:     if (stepm >= YEARM) hstepm=1;
                   5571:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5572:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5573:     mgp=matrix(1,npar,1,nlstate);
                   5574:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5575:     gp=vector(1,nlstate);
                   5576:     gm=vector(1,nlstate);
                   5577: 
                   5578:     for(theta=1; theta <=npar; theta++){
                   5579:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5580:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5581:       }
1.209     brouard  5582:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5583:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5584:       else
1.235     brouard  5585:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5586:       for(i=1;i<=nlstate;i++){
1.126     brouard  5587:        gp[i] = prlim[i][i];
1.208     brouard  5588:        mgp[theta][i] = prlim[i][i];
                   5589:       }
1.126     brouard  5590:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5591:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5592:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5593:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5594:       else
1.235     brouard  5595:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5596:       for(i=1;i<=nlstate;i++){
1.126     brouard  5597:        gm[i] = prlim[i][i];
1.208     brouard  5598:        mgm[theta][i] = prlim[i][i];
                   5599:       }
1.126     brouard  5600:       for(i=1;i<=nlstate;i++)
                   5601:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5602:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5603:     } /* End theta */
                   5604: 
                   5605:     trgradg =matrix(1,nlstate,1,npar);
                   5606: 
                   5607:     for(j=1; j<=nlstate;j++)
                   5608:       for(theta=1; theta <=npar; theta++)
                   5609:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5610:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5611:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5612:     /*   for(j=1; j<=nlstate;j++){ */
                   5613:     /*         printf(" %d ",j); */
                   5614:     /*         for(theta=1; theta <=npar; theta++) */
                   5615:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5616:     /*         printf("\n "); */
                   5617:     /*   } */
                   5618:     /* } */
                   5619:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5620:     /*   printf("\n gradg %d ",(int)age); */
                   5621:     /*   for(j=1; j<=nlstate;j++){ */
                   5622:     /*         printf("%d ",j); */
                   5623:     /*         for(theta=1; theta <=npar; theta++) */
                   5624:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   5625:     /*         printf("\n "); */
                   5626:     /*   } */
                   5627:     /* } */
1.126     brouard  5628: 
                   5629:     for(i=1;i<=nlstate;i++)
                   5630:       varpl[i][(int)age] =0.;
1.209     brouard  5631:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  5632:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5633:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   5634:     }else{
1.126     brouard  5635:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   5636:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  5637:     }
1.126     brouard  5638:     for(i=1;i<=nlstate;i++)
                   5639:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   5640: 
                   5641:     fprintf(ficresvpl,"%.0f ",age );
                   5642:     for(i=1; i<=nlstate;i++)
                   5643:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   5644:     fprintf(ficresvpl,"\n");
                   5645:     free_vector(gp,1,nlstate);
                   5646:     free_vector(gm,1,nlstate);
1.208     brouard  5647:     free_matrix(mgm,1,npar,1,nlstate);
                   5648:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  5649:     free_matrix(gradg,1,npar,1,nlstate);
                   5650:     free_matrix(trgradg,1,nlstate,1,npar);
                   5651:   } /* End age */
                   5652: 
                   5653:   free_vector(xp,1,npar);
                   5654:   free_matrix(doldm,1,nlstate,1,npar);
                   5655:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   5656: 
                   5657: }
                   5658: 
                   5659: /************ Variance of one-step probabilities  ******************/
                   5660: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  5661:  {
                   5662:    int i, j=0,  k1, l1, tj;
                   5663:    int k2, l2, j1,  z1;
                   5664:    int k=0, l;
                   5665:    int first=1, first1, first2;
                   5666:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   5667:    double **dnewm,**doldm;
                   5668:    double *xp;
                   5669:    double *gp, *gm;
                   5670:    double **gradg, **trgradg;
                   5671:    double **mu;
                   5672:    double age, cov[NCOVMAX+1];
                   5673:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   5674:    int theta;
                   5675:    char fileresprob[FILENAMELENGTH];
                   5676:    char fileresprobcov[FILENAMELENGTH];
                   5677:    char fileresprobcor[FILENAMELENGTH];
                   5678:    double ***varpij;
                   5679: 
                   5680:    strcpy(fileresprob,"PROB_"); 
                   5681:    strcat(fileresprob,fileres);
                   5682:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   5683:      printf("Problem with resultfile: %s\n", fileresprob);
                   5684:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   5685:    }
                   5686:    strcpy(fileresprobcov,"PROBCOV_"); 
                   5687:    strcat(fileresprobcov,fileresu);
                   5688:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   5689:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   5690:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   5691:    }
                   5692:    strcpy(fileresprobcor,"PROBCOR_"); 
                   5693:    strcat(fileresprobcor,fileresu);
                   5694:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   5695:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   5696:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   5697:    }
                   5698:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5699:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   5700:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5701:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   5702:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5703:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   5704:    pstamp(ficresprob);
                   5705:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   5706:    fprintf(ficresprob,"# Age");
                   5707:    pstamp(ficresprobcov);
                   5708:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   5709:    fprintf(ficresprobcov,"# Age");
                   5710:    pstamp(ficresprobcor);
                   5711:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   5712:    fprintf(ficresprobcor,"# Age");
1.126     brouard  5713: 
                   5714: 
1.222     brouard  5715:    for(i=1; i<=nlstate;i++)
                   5716:      for(j=1; j<=(nlstate+ndeath);j++){
                   5717:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   5718:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   5719:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   5720:      }  
                   5721:    /* fprintf(ficresprob,"\n");
                   5722:       fprintf(ficresprobcov,"\n");
                   5723:       fprintf(ficresprobcor,"\n");
                   5724:    */
                   5725:    xp=vector(1,npar);
                   5726:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5727:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5728:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   5729:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   5730:    first=1;
                   5731:    fprintf(ficgp,"\n# Routine varprob");
                   5732:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   5733:    fprintf(fichtm,"\n");
                   5734: 
                   5735:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   5736:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   5737:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  5738: and drawn. It helps understanding how is the covariance between two incidences.\
                   5739:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  5740:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  5741: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   5742: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   5743: standard deviations wide on each axis. <br>\
                   5744:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   5745:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   5746: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   5747: 
1.222     brouard  5748:    cov[1]=1;
                   5749:    /* tj=cptcoveff; */
1.225     brouard  5750:    tj = (int) pow(2,cptcoveff);
1.222     brouard  5751:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   5752:    j1=0;
1.224     brouard  5753:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  5754:      if  (cptcovn>0) {
                   5755:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  5756:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5757:        fprintf(ficresprob, "**********\n#\n");
                   5758:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  5759:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5760:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  5761:                        
1.222     brouard  5762:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  5763:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5764:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  5765:                        
                   5766:                        
1.222     brouard  5767:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  5768:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5769:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  5770:                        
1.222     brouard  5771:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  5772:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  5773:        fprintf(ficresprobcor, "**********\n#");    
                   5774:        if(invalidvarcomb[j1]){
                   5775:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   5776:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   5777:         continue;
                   5778:        }
                   5779:      }
                   5780:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   5781:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   5782:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   5783:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   5784:      for (age=bage; age<=fage; age ++){ 
                   5785:        cov[2]=age;
                   5786:        if(nagesqr==1)
                   5787:         cov[3]= age*age;
                   5788:        for (k=1; k<=cptcovn;k++) {
                   5789:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   5790:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   5791:                                                                    * 1  1 1 1 1
                   5792:                                                                    * 2  2 1 1 1
                   5793:                                                                    * 3  1 2 1 1
                   5794:                                                                    */
                   5795:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   5796:        }
                   5797:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   5798:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   5799:        for (k=1; k<=cptcovprod;k++)
                   5800:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  5801:                        
                   5802:                        
1.222     brouard  5803:        for(theta=1; theta <=npar; theta++){
                   5804:         for(i=1; i<=npar; i++)
                   5805:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  5806:                                
1.222     brouard  5807:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  5808:                                
1.222     brouard  5809:         k=0;
                   5810:         for(i=1; i<= (nlstate); i++){
                   5811:           for(j=1; j<=(nlstate+ndeath);j++){
                   5812:             k=k+1;
                   5813:             gp[k]=pmmij[i][j];
                   5814:           }
                   5815:         }
1.220     brouard  5816:                                
1.222     brouard  5817:         for(i=1; i<=npar; i++)
                   5818:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  5819:                                
1.222     brouard  5820:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   5821:         k=0;
                   5822:         for(i=1; i<=(nlstate); i++){
                   5823:           for(j=1; j<=(nlstate+ndeath);j++){
                   5824:             k=k+1;
                   5825:             gm[k]=pmmij[i][j];
                   5826:           }
                   5827:         }
1.220     brouard  5828:                                
1.222     brouard  5829:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   5830:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   5831:        }
1.126     brouard  5832: 
1.222     brouard  5833:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   5834:         for(theta=1; theta <=npar; theta++)
                   5835:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  5836:                        
1.222     brouard  5837:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   5838:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  5839:                        
1.222     brouard  5840:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  5841:                        
1.222     brouard  5842:        k=0;
                   5843:        for(i=1; i<=(nlstate); i++){
                   5844:         for(j=1; j<=(nlstate+ndeath);j++){
                   5845:           k=k+1;
                   5846:           mu[k][(int) age]=pmmij[i][j];
                   5847:         }
                   5848:        }
                   5849:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   5850:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   5851:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  5852:                        
1.222     brouard  5853:        /*printf("\n%d ",(int)age);
                   5854:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5855:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5856:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   5857:         }*/
1.220     brouard  5858:                        
1.222     brouard  5859:        fprintf(ficresprob,"\n%d ",(int)age);
                   5860:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   5861:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  5862:                        
1.222     brouard  5863:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   5864:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   5865:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   5866:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   5867:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   5868:        }
                   5869:        i=0;
                   5870:        for (k=1; k<=(nlstate);k++){
                   5871:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   5872:           i++;
                   5873:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   5874:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   5875:           for (j=1; j<=i;j++){
                   5876:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   5877:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   5878:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   5879:           }
                   5880:         }
                   5881:        }/* end of loop for state */
                   5882:      } /* end of loop for age */
                   5883:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   5884:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   5885:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   5886:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   5887:     
                   5888:      /* Confidence intervalle of pij  */
                   5889:      /*
                   5890:        fprintf(ficgp,"\nunset parametric;unset label");
                   5891:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   5892:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   5893:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   5894:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   5895:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   5896:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   5897:      */
                   5898:                
                   5899:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   5900:      first1=1;first2=2;
                   5901:      for (k2=1; k2<=(nlstate);k2++){
                   5902:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   5903:         if(l2==k2) continue;
                   5904:         j=(k2-1)*(nlstate+ndeath)+l2;
                   5905:         for (k1=1; k1<=(nlstate);k1++){
                   5906:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   5907:             if(l1==k1) continue;
                   5908:             i=(k1-1)*(nlstate+ndeath)+l1;
                   5909:             if(i<=j) continue;
                   5910:             for (age=bage; age<=fage; age ++){ 
                   5911:               if ((int)age %5==0){
                   5912:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   5913:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   5914:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   5915:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   5916:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   5917:                 c12=cv12/sqrt(v1*v2);
                   5918:                 /* Computing eigen value of matrix of covariance */
                   5919:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   5920:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   5921:                 if ((lc2 <0) || (lc1 <0) ){
                   5922:                   if(first2==1){
                   5923:                     first1=0;
                   5924:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   5925:                   }
                   5926:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   5927:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   5928:                   /* lc2=fabs(lc2); */
                   5929:                 }
1.220     brouard  5930:                                                                
1.222     brouard  5931:                 /* Eigen vectors */
                   5932:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   5933:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   5934:                 v21=(lc1-v1)/cv12*v11;
                   5935:                 v12=-v21;
                   5936:                 v22=v11;
                   5937:                 tnalp=v21/v11;
                   5938:                 if(first1==1){
                   5939:                   first1=0;
                   5940:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   5941:                 }
                   5942:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   5943:                 /*printf(fignu*/
                   5944:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   5945:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   5946:                 if(first==1){
                   5947:                   first=0;
                   5948:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   5949:                   fprintf(ficgp,"\nset parametric;unset label");
                   5950:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   5951:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   5952:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  5953:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  5954: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  5955:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   5956:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5957:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5958:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   5959:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5960:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   5961:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   5962:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   5963:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   5964:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   5965:                 }else{
                   5966:                   first=0;
                   5967:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   5968:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   5969:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   5970:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   5971:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   5972:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   5973:                 }/* if first */
                   5974:               } /* age mod 5 */
                   5975:             } /* end loop age */
                   5976:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   5977:             first=1;
                   5978:           } /*l12 */
                   5979:         } /* k12 */
                   5980:        } /*l1 */
                   5981:      }/* k1 */
                   5982:    }  /* loop on combination of covariates j1 */
                   5983:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   5984:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   5985:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   5986:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   5987:    free_vector(xp,1,npar);
                   5988:    fclose(ficresprob);
                   5989:    fclose(ficresprobcov);
                   5990:    fclose(ficresprobcor);
                   5991:    fflush(ficgp);
                   5992:    fflush(fichtmcov);
                   5993:  }
1.126     brouard  5994: 
                   5995: 
                   5996: /******************* Printing html file ***********/
1.201     brouard  5997: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  5998:                  int lastpass, int stepm, int weightopt, char model[],\
                   5999:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.217     brouard  6000:                  int popforecast, int prevfcast, int backcast, int estepm , \
1.213     brouard  6001:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6002:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237   ! brouard  6003:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6004: 
                   6005:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6006:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6007: </ul>");
1.237   ! brouard  6008:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
        !          6009: </ul>", model);
1.214     brouard  6010:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6011:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6012:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6013:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6014:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6015:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6016:    fprintf(fichtm,"\
                   6017:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6018:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6019:    fprintf(fichtm,"\
1.217     brouard  6020:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6021:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6022:    fprintf(fichtm,"\
1.126     brouard  6023:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6024:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6025:    fprintf(fichtm,"\
1.217     brouard  6026:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6027:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6028:    fprintf(fichtm,"\
1.211     brouard  6029:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6030:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6031:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6032:    if(prevfcast==1){
                   6033:      fprintf(fichtm,"\
                   6034:  - Prevalence projections by age and states:                           \
1.201     brouard  6035:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6036:    }
1.126     brouard  6037: 
1.222     brouard  6038:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6039: 
1.225     brouard  6040:    m=pow(2,cptcoveff);
1.222     brouard  6041:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6042: 
1.222     brouard  6043:    jj1=0;
1.237   ! brouard  6044: 
        !          6045:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.222     brouard  6046:    for(k1=1; k1<=m;k1++){
1.237   ! brouard  6047:      if(TKresult[nres]!= k1)
        !          6048:        continue;
1.220     brouard  6049: 
1.222     brouard  6050:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6051:      jj1++;
                   6052:      if (cptcovn > 0) {
                   6053:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6054:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237   ! brouard  6055:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
        !          6056:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
        !          6057:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
        !          6058:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6059:        }
1.237   ! brouard  6060:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6061:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6062:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
        !          6063:       }
        !          6064:        
1.230     brouard  6065:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6066:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6067:        if(invalidvarcomb[k1]){
                   6068:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6069:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6070:         continue;
                   6071:        }
                   6072:      }
                   6073:      /* aij, bij */
                   6074:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1.svg\">%s_%d-1.svg</a><br> \
1.211     brouard  6075: <img src=\"%s_%d-1.svg\">",model,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
1.222     brouard  6076:      /* Pij */
                   6077:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2.svg\">%s_%d-2.svg</a><br> \
1.201     brouard  6078: <img src=\"%s_%d-2.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);     
1.222     brouard  6079:      /* Quasi-incidences */
                   6080:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6081:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6082:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
                   6083: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3.svg\">%s_%d-3.svg</a><br> \
1.201     brouard  6084: <img src=\"%s_%d-3.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); 
1.222     brouard  6085:      /* Survival functions (period) in state j */
                   6086:      for(cpt=1; cpt<=nlstate;cpt++){
                   6087:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
1.201     brouard  6088: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1);
1.222     brouard  6089:      }
                   6090:      /* State specific survival functions (period) */
                   6091:      for(cpt=1; cpt<=nlstate;cpt++){
                   6092:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6093:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.201     brouard  6094:  <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> <img src=\"%s_%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1);
1.222     brouard  6095:      }
                   6096:      /* Period (stable) prevalence in each health state */
                   6097:      for(cpt=1; cpt<=nlstate;cpt++){
                   6098:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a><br> \
1.201     brouard  6099: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1);
1.222     brouard  6100:      }
                   6101:      if(backcast==1){
                   6102:        /* Period (stable) back prevalence in each health state */
                   6103:        for(cpt=1; cpt<=nlstate;cpt++){
                   6104:         fprintf(fichtm,"<br>\n- Convergence to period (stable) back prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a><br> \
1.217     brouard  6105: <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1,subdirf2(optionfilefiname,"PB_"),cpt,jj1);
1.222     brouard  6106:        }
1.217     brouard  6107:      }
1.222     brouard  6108:      if(prevfcast==1){
                   6109:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6110:        for(cpt=1; cpt<=nlstate;cpt++){
                   6111:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
1.213     brouard  6112: <img src=\"%s_%d-%d.svg\">", dateprev1, dateprev2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1,subdirf2(optionfilefiname,"PROJ_"),cpt,jj1);
1.222     brouard  6113:        }
                   6114:      }
1.220     brouard  6115:         
1.222     brouard  6116:      for(cpt=1; cpt<=nlstate;cpt++) {
                   6117:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d%d.svg\">%s_%d%d.svg</a> <br> \
1.201     brouard  6118: <img src=\"%s_%d%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1);
1.222     brouard  6119:      }
                   6120:      /* } /\* end i1 *\/ */
                   6121:    }/* End k1 */
                   6122:    fprintf(fichtm,"</ul>");
1.126     brouard  6123: 
1.222     brouard  6124:    fprintf(fichtm,"\
1.126     brouard  6125: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6126:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6127:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6128: But because parameters are usually highly correlated (a higher incidence of disability \
                   6129: and a higher incidence of recovery can give very close observed transition) it might \
                   6130: be very useful to look not only at linear confidence intervals estimated from the \
                   6131: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6132: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6133: covariance matrix of the one-step probabilities. \
                   6134: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6135: 
1.222     brouard  6136:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6137:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6138:    fprintf(fichtm,"\
1.126     brouard  6139:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6140:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6141: 
1.222     brouard  6142:    fprintf(fichtm,"\
1.126     brouard  6143:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6144:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6145:    fprintf(fichtm,"\
1.126     brouard  6146:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6147:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6148:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6149:    fprintf(fichtm,"\
1.126     brouard  6150:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6151:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6152:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6153:    fprintf(fichtm,"\
1.128     brouard  6154:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6155:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6156:    fprintf(fichtm,"\
1.128     brouard  6157:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6158:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6159:    fprintf(fichtm,"\
1.126     brouard  6160:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6161:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6162: 
                   6163: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6164: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6165: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6166: /*     <br>",fileres,fileres,fileres,fileres); */
                   6167: /*  else  */
                   6168: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6169:    fflush(fichtm);
                   6170:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6171: 
1.225     brouard  6172:    m=pow(2,cptcoveff);
1.222     brouard  6173:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6174: 
1.222     brouard  6175:    jj1=0;
1.237   ! brouard  6176: 
        !          6177:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.222     brouard  6178:    for(k1=1; k1<=m;k1++){
1.237   ! brouard  6179:      if(TKresult[nres]!= k1)
        !          6180:        continue;
1.222     brouard  6181:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6182:      jj1++;
1.126     brouard  6183:      if (cptcovn > 0) {
                   6184:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6185:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237   ! brouard  6186:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
        !          6187:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
        !          6188:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6189:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6190:       }
        !          6191: 
1.126     brouard  6192:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6193: 
1.222     brouard  6194:        if(invalidvarcomb[k1]){
                   6195:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6196:         continue;
                   6197:        }
1.126     brouard  6198:      }
                   6199:      for(cpt=1; cpt<=nlstate;cpt++) {
1.218     brouard  6200:        fprintf(fichtm,"\n<br>- Observed (cross-sectional) and period (incidence based) \
                   6201: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d.svg\"> %s_%d-%d.svg</a>\n <br>\
1.205     brouard  6202: <img src=\"%s_%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1);  
1.126     brouard  6203:      }
                   6204:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6205: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6206: true period expectancies (those weighted with period prevalences are also\
                   6207:  drawn in addition to the population based expectancies computed using\
1.218     brouard  6208:  observed and cahotic prevalences:  <a href=\"%s_%d.svg\">%s_%d.svg</a>\n<br>\
1.205     brouard  6209: <img src=\"%s_%d.svg\">",subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1);
1.222     brouard  6210:      /* } /\* end i1 *\/ */
                   6211:    }/* End k1 */
                   6212:    fprintf(fichtm,"</ul>");
                   6213:    fflush(fichtm);
1.126     brouard  6214: }
                   6215: 
                   6216: /******************* Gnuplot file **************/
1.223     brouard  6217: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6218: 
                   6219:   char dirfileres[132],optfileres[132];
1.223     brouard  6220:   char gplotcondition[132];
1.237   ! brouard  6221:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6222:   int lv=0, vlv=0, kl=0;
1.130     brouard  6223:   int ng=0;
1.201     brouard  6224:   int vpopbased;
1.223     brouard  6225:   int ioffset; /* variable offset for columns */
1.235     brouard  6226:   int nres=0; /* Index of resultline */
1.219     brouard  6227: 
1.126     brouard  6228: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6229: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6230: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6231: /*   } */
                   6232: 
                   6233:   /*#ifdef windows */
                   6234:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6235:   /*#endif */
1.225     brouard  6236:   m=pow(2,cptcoveff);
1.126     brouard  6237: 
1.202     brouard  6238:   /* Contribution to likelihood */
                   6239:   /* Plot the probability implied in the likelihood */
1.223     brouard  6240:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6241:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6242:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6243:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6244: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6245:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6246: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6247:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6248:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6249:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6250:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6251:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6252:   for (i=1; i<= nlstate ; i ++) {
                   6253:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6254:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6255:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6256:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6257:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6258:     }
                   6259:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6260:   }
                   6261:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6262:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6263:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6264:   fprintf(ficgp,"\nset out;unset log\n");
                   6265:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6266: 
1.126     brouard  6267:   strcpy(dirfileres,optionfilefiname);
                   6268:   strcpy(optfileres,"vpl");
1.223     brouard  6269:   /* 1eme*/
1.211     brouard  6270:   for (cpt=1; cpt<= nlstate ; cpt ++) { /* For each live state */
1.236     brouard  6271:     for (k1=1; k1<= m ; k1 ++) /* For each valid combination of covariate */
                   6272:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.235     brouard  6273:     /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
                   6274:       if(TKresult[nres]!= k1)
                   6275:        continue;
                   6276:       /* We are interested in selected combination by the resultline */
                   6277:       printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt);
                   6278:       fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.225     brouard  6279:       for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6280:        lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
1.223     brouard  6281:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6282:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6283:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6284:        vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6285:        /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.235     brouard  6286:        printf(" V%d=%d ",Tvaraff[k],vlv);
1.223     brouard  6287:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6288:       }
1.235     brouard  6289:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6290:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6291:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6292:       }        
                   6293:       printf("\n#\n");
1.211     brouard  6294:       fprintf(ficgp,"\n#\n");
1.223     brouard  6295:       if(invalidvarcomb[k1]){
                   6296:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6297:        continue;
                   6298:       }
1.235     brouard  6299:       
1.223     brouard  6300:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1);
                   6301:       fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1);
                   6302:       fprintf(ficgp,"set xlabel \"Age\" \n\
1.235     brouard  6303: set ylabel \"Probability\" \n            \
                   6304: set ter svg size 640, 480\n                                            \
1.201     brouard  6305: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1);
1.235     brouard  6306:       
1.223     brouard  6307:       for (i=1; i<= nlstate ; i ++) {
                   6308:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6309:        else        fprintf(ficgp," %%*lf (%%*lf)");
                   6310:       }
                   6311:       fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1);
                   6312:       for (i=1; i<= nlstate ; i ++) {
                   6313:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6314:        else fprintf(ficgp," %%*lf (%%*lf)");
                   6315:       } 
                   6316:       fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); 
                   6317:       for (i=1; i<= nlstate ; i ++) {
                   6318:        if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6319:        else fprintf(ficgp," %%*lf (%%*lf)");
                   6320:       }  
                   6321:       fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6322:       if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6323:        /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
                   6324:        fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1 */
1.225     brouard  6325:        if(cptcoveff ==0){
1.223     brouard  6326:          fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line ",  2+(cpt-1),  cpt );
                   6327:        }else{
                   6328:          kl=0;
1.225     brouard  6329:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6330:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
1.223     brouard  6331:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6332:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6333:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6334:            vlv= nbcode[Tvaraff[k]][lv];
                   6335:            kl++;
                   6336:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6337:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6338:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6339:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
1.225     brouard  6340:            if(k==cptcoveff){
1.227     brouard  6341:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   6342:                      4+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.223     brouard  6343:            }else{
                   6344:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6345:              kl++;
                   6346:            }
                   6347:          } /* end covariate */
                   6348:        } /* end if no covariate */
                   6349:       } /* end if backcast */
                   6350:       fprintf(ficgp,"\nset out \n");
1.201     brouard  6351:     } /* k1 */
                   6352:   } /* cpt */
1.235     brouard  6353: 
                   6354:   
1.126     brouard  6355:   /*2 eme*/
1.236     brouard  6356:   for (k1=1; k1<= m ; k1 ++)  
                   6357:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6358:     if(TKresult[nres]!= k1)
                   6359:       continue;
1.223     brouard  6360:     fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.225     brouard  6361:     for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6362:       lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6363:       /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6364:       /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6365:       /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6366:       vlv= nbcode[Tvaraff[k]][lv];
                   6367:       fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.236     brouard  6368:     }
                   6369:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6370:       printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6371:       fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.223     brouard  6372:     }
                   6373:     fprintf(ficgp,"\n#\n");
                   6374:     if(invalidvarcomb[k1]){
                   6375:       fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6376:       continue;
                   6377:     }
1.219     brouard  6378:                        
1.223     brouard  6379:     fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1);
                   6380:     for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6381:       if(vpopbased==0)
                   6382:        fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6383:       else
                   6384:        fprintf(ficgp,"\nreplot ");
                   6385:       for (i=1; i<= nlstate+1 ; i ++) {
                   6386:        k=2*i;
                   6387:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6388:        for (j=1; j<= nlstate+1 ; j ++) {
                   6389:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6390:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6391:        }   
                   6392:        if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6393:        else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6394:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6395:        for (j=1; j<= nlstate+1 ; j ++) {
                   6396:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6397:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6398:        }   
                   6399:        fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6400:        fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6401:        for (j=1; j<= nlstate+1 ; j ++) {
                   6402:          if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6403:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6404:        }   
                   6405:        if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6406:        else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6407:       } /* state */
                   6408:     } /* vpopbased */
                   6409:     fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */
1.235     brouard  6410:   } /* k1 end 2 eme*/
1.219     brouard  6411:        
                   6412:        
1.126     brouard  6413:   /*3eme*/
1.236     brouard  6414:   for (k1=1; k1<= m ; k1 ++) 
                   6415:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6416:     if(TKresult[nres]!= k)
                   6417:       continue;
1.220     brouard  6418: 
1.126     brouard  6419:     for (cpt=1; cpt<= nlstate ; cpt ++) {
1.236     brouard  6420:       fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.237   ! brouard  6421:       for (k=1; k<=cptcoveff; k++){    /* For each covariate dummy combination and each value */
1.225     brouard  6422:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6423:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6424:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6425:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6426:        vlv= nbcode[Tvaraff[k]][lv];
                   6427:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6428:       }
1.237   ! brouard  6429:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6430:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6431:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6432:       }        
1.211     brouard  6433:       fprintf(ficgp,"\n#\n");
1.223     brouard  6434:       if(invalidvarcomb[k1]){
                   6435:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6436:        continue;
                   6437:       }
1.219     brouard  6438:                        
1.126     brouard  6439:       /*       k=2+nlstate*(2*cpt-2); */
                   6440:       k=2+(nlstate+1)*(cpt-1);
1.201     brouard  6441:       fprintf(ficgp,"\nset out \"%s_%d%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1);
1.199     brouard  6442:       fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6443: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.126     brouard  6444:       /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
1.223     brouard  6445:        for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6446:        fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6447:        fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6448:        for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6449:        fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6450:                                
1.126     brouard  6451:       */
                   6452:       for (i=1; i< nlstate ; i ++) {
1.223     brouard  6453:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6454:        /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6455:                                
1.126     brouard  6456:       } 
1.201     brouard  6457:       fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
1.126     brouard  6458:     }
                   6459:   }
                   6460:   
1.223     brouard  6461:   /* 4eme */
1.201     brouard  6462:   /* Survival functions (period) from state i in state j by initial state i */
1.237   ! brouard  6463:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
        !          6464:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
        !          6465:     if(TKresult[nres]!= k1)
1.236     brouard  6466:       continue;
1.220     brouard  6467: 
1.201     brouard  6468:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.211     brouard  6469:       fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
1.237   ! brouard  6470:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6471:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6472:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6473:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6474:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6475:        vlv= nbcode[Tvaraff[k]][lv];
                   6476:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6477:       }
1.236     brouard  6478:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6479:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6480:       }        
1.211     brouard  6481:       fprintf(ficgp,"\n#\n");
1.223     brouard  6482:       if(invalidvarcomb[k1]){
                   6483:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6484:        continue;
                   6485:       }
1.220     brouard  6486:                        
1.201     brouard  6487:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1);
                   6488:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
1.220     brouard  6489: set ter svg size 640, 480\n                                                                                                                                                                                    \
                   6490: unset log y\n                                                                                                                                                                                                                                          \
1.201     brouard  6491: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6492:       k=3;
1.201     brouard  6493:       for (i=1; i<= nlstate ; i ++){
1.223     brouard  6494:        if(i==1){
                   6495:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6496:        }else{
                   6497:          fprintf(ficgp,", '' ");
                   6498:        }
                   6499:        l=(nlstate+ndeath)*(i-1)+1;
                   6500:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6501:        for (j=2; j<= nlstate+ndeath ; j ++)
                   6502:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6503:        fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
1.201     brouard  6504:       } /* nlstate */
                   6505:       fprintf(ficgp,"\nset out\n");
                   6506:     } /* end cpt state*/ 
                   6507:   } /* end covariate */  
1.220     brouard  6508:        
                   6509: /* 5eme */
1.201     brouard  6510:   /* Survival functions (period) from state i in state j by final state j */
1.236     brouard  6511:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6512:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   6513:     if(TKresult[nres]!= k1)
                   6514:       continue;
1.201     brouard  6515:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.223     brouard  6516:                        
1.201     brouard  6517:       fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
1.225     brouard  6518:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6519:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6520:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6521:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6522:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6523:        vlv= nbcode[Tvaraff[k]][lv];
                   6524:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6525:       }
1.236     brouard  6526:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6527:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6528:       }        
1.211     brouard  6529:       fprintf(ficgp,"\n#\n");
1.223     brouard  6530:       if(invalidvarcomb[k1]){
1.227     brouard  6531:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6532:        continue;
1.223     brouard  6533:       }
1.227     brouard  6534:       
1.201     brouard  6535:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1);
                   6536:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
1.227     brouard  6537: set ter svg size 640, 480\n                                            \
                   6538: unset log y\n                                                          \
1.201     brouard  6539: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6540:       k=3;
1.201     brouard  6541:       for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
1.227     brouard  6542:        if(j==1)
                   6543:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6544:        else
                   6545:          fprintf(ficgp,", '' ");
                   6546:        l=(nlstate+ndeath)*(cpt-1) +j;
                   6547:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6548:        /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6549:        /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6550:        fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
1.201     brouard  6551:       } /* nlstate */
                   6552:       fprintf(ficgp,", '' ");
                   6553:       fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6554:       for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
1.227     brouard  6555:        l=(nlstate+ndeath)*(cpt-1) +j;
                   6556:        if(j < nlstate)
                   6557:          fprintf(ficgp,"$%d +",k+l);
                   6558:        else
                   6559:          fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
1.201     brouard  6560:       }
                   6561:       fprintf(ficgp,"\nset out\n");
                   6562:     } /* end cpt state*/ 
                   6563:   } /* end covariate */  
1.227     brouard  6564:   
1.220     brouard  6565: /* 6eme */
1.202     brouard  6566:   /* CV preval stable (period) for each covariate */
1.237   ! brouard  6567:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
        !          6568:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
        !          6569:     if(TKresult[nres]!= k1)
        !          6570:       continue;
1.153     brouard  6571:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6572:       
1.211     brouard  6573:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6574:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6575:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6576:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6577:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6578:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6579:        vlv= nbcode[Tvaraff[k]][lv];
                   6580:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6581:       }
1.237   ! brouard  6582:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6583:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6584:       }        
1.211     brouard  6585:       fprintf(ficgp,"\n#\n");
1.223     brouard  6586:       if(invalidvarcomb[k1]){
1.227     brouard  6587:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6588:        continue;
1.223     brouard  6589:       }
1.227     brouard  6590:       
1.201     brouard  6591:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1);
1.126     brouard  6592:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.227     brouard  6593: set ter svg size 640, 480\n                                            \
                   6594: unset log y\n                                                          \
1.153     brouard  6595: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6596:       k=3; /* Offset */
1.153     brouard  6597:       for (i=1; i<= nlstate ; i ++){
1.227     brouard  6598:        if(i==1)
                   6599:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6600:        else
                   6601:          fprintf(ficgp,", '' ");
                   6602:        l=(nlstate+ndeath)*(i-1)+1;
                   6603:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6604:        for (j=2; j<= nlstate ; j ++)
                   6605:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6606:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6607:       } /* nlstate */
1.201     brouard  6608:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6609:     } /* end cpt state*/ 
                   6610:   } /* end covariate */  
1.227     brouard  6611:   
                   6612:   
1.220     brouard  6613: /* 7eme */
1.218     brouard  6614:   if(backcast == 1){
1.217     brouard  6615:     /* CV back preval stable (period) for each covariate */
1.237   ! brouard  6616:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
        !          6617:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
        !          6618:       if(TKresult[nres]!= k1)
        !          6619:        continue;
1.218     brouard  6620:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6621:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
                   6622:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6623:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6624:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6625:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  6626:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  6627:          vlv= nbcode[Tvaraff[k]][lv];
                   6628:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6629:        }
1.237   ! brouard  6630:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6631:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6632:        }       
1.227     brouard  6633:        fprintf(ficgp,"\n#\n");
                   6634:        if(invalidvarcomb[k1]){
                   6635:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6636:          continue;
                   6637:        }
                   6638:        
                   6639:        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1);
                   6640:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
                   6641: set ter svg size 640, 480\n                                            \
                   6642: unset log y\n                                                          \
1.218     brouard  6643: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6644:        k=3; /* Offset */
                   6645:        for (i=1; i<= nlstate ; i ++){
                   6646:          if(i==1)
                   6647:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   6648:          else
                   6649:            fprintf(ficgp,", '' ");
                   6650:          /* l=(nlstate+ndeath)*(i-1)+1; */
                   6651:          l=(nlstate+ndeath)*(cpt-1)+1;
                   6652:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   6653:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
                   6654:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+(cpt-1)+i-1); /* a vérifier */
                   6655:          /* for (j=2; j<= nlstate ; j ++) */
                   6656:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   6657:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   6658:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   6659:        } /* nlstate */
                   6660:        fprintf(ficgp,"\nset out\n");
1.218     brouard  6661:       } /* end cpt state*/ 
                   6662:     } /* end covariate */  
                   6663:   } /* End if backcast */
                   6664:   
1.223     brouard  6665:   /* 8eme */
1.218     brouard  6666:   if(prevfcast==1){
                   6667:     /* Projection from cross-sectional to stable (period) for each covariate */
                   6668:     
1.237   ! brouard  6669:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
        !          6670:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
        !          6671:       if(TKresult[nres]!= k1)
        !          6672:        continue;
1.211     brouard  6673:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  6674:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   6675:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   6676:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6677:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6678:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6679:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6680:          vlv= nbcode[Tvaraff[k]][lv];
                   6681:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6682:        }
1.237   ! brouard  6683:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6684:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6685:        }       
1.227     brouard  6686:        fprintf(ficgp,"\n#\n");
                   6687:        if(invalidvarcomb[k1]){
                   6688:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6689:          continue;
                   6690:        }
                   6691:        
                   6692:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
                   6693:        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1);
                   6694:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   6695: set ter svg size 640, 480\n                                            \
                   6696: unset log y\n                                                          \
1.219     brouard  6697: plot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  6698:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   6699:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6700:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6701:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6702:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   6703:          if(i==1){
                   6704:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   6705:          }else{
                   6706:            fprintf(ficgp,",\\\n '' ");
                   6707:          }
                   6708:          if(cptcoveff ==0){ /* No covariate */
                   6709:            ioffset=2; /* Age is in 2 */
                   6710:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6711:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6712:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   6713:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   6714:            fprintf(ficgp," u %d:(", ioffset); 
                   6715:            if(i==nlstate+1)
                   6716:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   6717:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6718:            else
                   6719:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   6720:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6721:          }else{ /* more than 2 covariates */
                   6722:            if(cptcoveff ==1){
                   6723:              ioffset=4; /* Age is in 4 */
                   6724:            }else{
                   6725:              ioffset=6; /* Age is in 6 */
                   6726:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   6727:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   6728:            }   
                   6729:            fprintf(ficgp," u %d:(",ioffset); 
                   6730:            kl=0;
                   6731:            strcpy(gplotcondition,"(");
                   6732:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   6733:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   6734:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6735:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6736:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6737:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   6738:              kl++;
                   6739:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   6740:              kl++;
                   6741:              if(k <cptcoveff && cptcoveff>1)
                   6742:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   6743:            }
                   6744:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   6745:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6746:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6747:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6748:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6749:            if(i==nlstate+1){
                   6750:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   6751:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   6752:            }else{
                   6753:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   6754:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   6755:            }
                   6756:          } /* end if covariate */
                   6757:        } /* nlstate */
                   6758:        fprintf(ficgp,"\nset out\n");
1.223     brouard  6759:       } /* end cpt state*/
                   6760:     } /* end covariate */
                   6761:   } /* End if prevfcast */
1.227     brouard  6762:   
                   6763:   
1.223     brouard  6764:   /* proba elementaires */
                   6765:   fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n");
1.126     brouard  6766:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  6767:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  6768:     for(k=1; k <=(nlstate+ndeath); k++){
                   6769:       if (k != i) {
1.227     brouard  6770:        fprintf(ficgp,"#   current state %d\n",k);
                   6771:        for(j=1; j <=ncovmodel; j++){
                   6772:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   6773:          jk++; 
                   6774:        }
                   6775:        fprintf(ficgp,"\n");
1.126     brouard  6776:       }
                   6777:     }
1.223     brouard  6778:   }
1.187     brouard  6779:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  6780:   
1.145     brouard  6781:   /*goto avoid;*/
1.200     brouard  6782:   fprintf(ficgp,"\n##############\n#Graphics of probabilities or incidences\n#############\n");
1.187     brouard  6783:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   6784:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   6785:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   6786:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   6787:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6788:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6789:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6790:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   6791:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   6792:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   6793:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   6794:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   6795:   fprintf(ficgp,"#\n");
1.223     brouard  6796:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.237   ! brouard  6797:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year \n");
        !          6798:     fprintf(ficgp,"#model=%s \n",model);
1.223     brouard  6799:     fprintf(ficgp,"# ng=%d\n",ng);
1.237   ! brouard  6800:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
        !          6801:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
        !          6802:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
        !          6803:       if(TKresult[nres]!= jk)
        !          6804:        continue;
        !          6805:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
        !          6806:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
        !          6807:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
        !          6808:       }        
        !          6809:       fprintf(ficgp,"\n#\n");
1.223     brouard  6810:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng);
                   6811:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   6812:       if (ng==1){
                   6813:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   6814:        fprintf(ficgp,"\nunset log y");
                   6815:       }else if (ng==2){
                   6816:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   6817:        fprintf(ficgp,"\nset log y");
                   6818:       }else if (ng==3){
                   6819:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   6820:        fprintf(ficgp,"\nset log y");
                   6821:       }else
                   6822:        fprintf(ficgp,"\nunset title ");
                   6823:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   6824:       i=1;
                   6825:       for(k2=1; k2<=nlstate; k2++) {
                   6826:        k3=i;
                   6827:        for(k=1; k<=(nlstate+ndeath); k++) {
                   6828:          if (k != k2){
                   6829:            switch( ng) {
                   6830:            case 1:
                   6831:              if(nagesqr==0)
                   6832:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   6833:              else /* nagesqr =1 */
                   6834:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6835:              break;
                   6836:            case 2: /* ng=2 */
                   6837:              if(nagesqr==0)
                   6838:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   6839:              else /* nagesqr =1 */
                   6840:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   6841:              break;
                   6842:            case 3:
                   6843:              if(nagesqr==0)
                   6844:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   6845:              else /* nagesqr =1 */
                   6846:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   6847:              break;
                   6848:            }
                   6849:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237   ! brouard  6850:            ijp=1; /* product no age */
        !          6851:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
        !          6852:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  6853:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237   ! brouard  6854:              if(j==Tage[ij]) { /* Product by age */
        !          6855:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
        !          6856:                  if(Dummy[j]==0){
        !          6857:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
        !          6858:                  }else{ /* quantitative */
        !          6859:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
        !          6860:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
        !          6861:                  }
        !          6862:                  ij++;
        !          6863:                }
        !          6864:              }else if(j==Tprod[ijp]) { /* */ 
        !          6865:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
        !          6866:                if(ijp <=cptcovprod) { /* Product */
        !          6867:                  if(Dummy[Tvard[ijp][1]]==0){/* Vn is dummy */
        !          6868:                    if(Dummy[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
        !          6869:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
        !          6870:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
        !          6871:                    }else{ /* Vn is dummy and Vm is quanti */
        !          6872:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
        !          6873:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
        !          6874:                    }
        !          6875:                  }else{ /* Vn*Vm Vn is quanti */
        !          6876:                    if(Dummy[Tvard[ijp][2]]==0){
        !          6877:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
        !          6878:                    }else{ /* Both quanti */
        !          6879:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
        !          6880:                    }
        !          6881:                  }
        !          6882:                }
        !          6883:              } else{  /* simple covariate */
        !          6884:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
        !          6885:                if(Dummy[j]==0){
        !          6886:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
        !          6887:                }else{ /* quantitative */
        !          6888:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  6889:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6890:                }
1.237   ! brouard  6891:              } /* end simple */
        !          6892:            } /* end j */
1.223     brouard  6893:          }else{
                   6894:            i=i-ncovmodel;
                   6895:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   6896:              fprintf(ficgp," (1.");
                   6897:          }
1.227     brouard  6898:          
1.223     brouard  6899:          if(ng != 1){
                   6900:            fprintf(ficgp,")/(1");
1.227     brouard  6901:            
1.223     brouard  6902:            for(k1=1; k1 <=nlstate; k1++){ 
                   6903:              if(nagesqr==0)
                   6904:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   6905:              else /* nagesqr =1 */
                   6906:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  6907:               
1.223     brouard  6908:              ij=1;
                   6909:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237   ! brouard  6910:                if((j-2)==Tage[ij]) { /* Bug valgrind */
        !          6911:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  6912:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   6913:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   6914:                    ij++;
                   6915:                  }
                   6916:                }
                   6917:                else
1.225     brouard  6918:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  6919:              }
                   6920:              fprintf(ficgp,")");
                   6921:            }
                   6922:            fprintf(ficgp,")");
                   6923:            if(ng ==2)
                   6924:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   6925:            else /* ng= 3 */
                   6926:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   6927:          }else{ /* end ng <> 1 */
                   6928:            if( k !=k2) /* logit p11 is hard to draw */
                   6929:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   6930:          }
                   6931:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   6932:            fprintf(ficgp,",");
                   6933:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   6934:            fprintf(ficgp,",");
                   6935:          i=i+ncovmodel;
                   6936:        } /* end k */
                   6937:       } /* end k2 */
                   6938:       fprintf(ficgp,"\n set out\n");
                   6939:     } /* end jk */
                   6940:   } /* end ng */
                   6941:   /* avoid: */
                   6942:   fflush(ficgp); 
1.126     brouard  6943: }  /* end gnuplot */
                   6944: 
                   6945: 
                   6946: /*************** Moving average **************/
1.219     brouard  6947: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  6948:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  6949:    
1.222     brouard  6950:    int i, cpt, cptcod;
                   6951:    int modcovmax =1;
                   6952:    int mobilavrange, mob;
                   6953:    int iage=0;
                   6954: 
                   6955:    double sum=0.;
                   6956:    double age;
                   6957:    double *sumnewp, *sumnewm;
                   6958:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   6959:   
                   6960:   
1.225     brouard  6961:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  6962:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   6963: 
                   6964:    sumnewp = vector(1,ncovcombmax);
                   6965:    sumnewm = vector(1,ncovcombmax);
                   6966:    agemingood = vector(1,ncovcombmax); 
                   6967:    agemaxgood = vector(1,ncovcombmax);
                   6968: 
                   6969:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6970:      sumnewm[cptcod]=0.;
                   6971:      sumnewp[cptcod]=0.;
                   6972:      agemingood[cptcod]=0;
                   6973:      agemaxgood[cptcod]=0;
                   6974:    }
                   6975:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   6976:   
                   6977:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   6978:      if(mobilav==1) mobilavrange=5; /* default */
                   6979:      else mobilavrange=mobilav;
                   6980:      for (age=bage; age<=fage; age++)
                   6981:        for (i=1; i<=nlstate;i++)
                   6982:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   6983:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   6984:      /* We keep the original values on the extreme ages bage, fage and for 
                   6985:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   6986:        we use a 5 terms etc. until the borders are no more concerned. 
                   6987:      */ 
                   6988:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   6989:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   6990:         for (i=1; i<=nlstate;i++){
                   6991:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   6992:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   6993:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   6994:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   6995:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   6996:             }
                   6997:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   6998:           }
                   6999:         }
                   7000:        }/* end age */
                   7001:      }/* end mob */
                   7002:    }else
                   7003:      return -1;
                   7004:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7005:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7006:      if(invalidvarcomb[cptcod]){
                   7007:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7008:        continue;
                   7009:      }
1.219     brouard  7010: 
1.222     brouard  7011:      agemingood[cptcod]=fage-(mob-1)/2;
                   7012:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7013:        sumnewm[cptcod]=0.;
                   7014:        for (i=1; i<=nlstate;i++){
                   7015:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7016:        }
                   7017:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7018:         agemingood[cptcod]=age;
                   7019:        }else{ /* bad */
                   7020:         for (i=1; i<=nlstate;i++){
                   7021:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7022:         } /* i */
                   7023:        } /* end bad */
                   7024:      }/* age */
                   7025:      sum=0.;
                   7026:      for (i=1; i<=nlstate;i++){
                   7027:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7028:      }
                   7029:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7030:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7031:        /* for (i=1; i<=nlstate;i++){ */
                   7032:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7033:        /* } /\* i *\/ */
                   7034:      } /* end bad */
                   7035:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7036:      /* From youngest, finding the oldest wrong */
                   7037:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7038:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7039:        sumnewm[cptcod]=0.;
                   7040:        for (i=1; i<=nlstate;i++){
                   7041:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7042:        }
                   7043:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7044:         agemaxgood[cptcod]=age;
                   7045:        }else{ /* bad */
                   7046:         for (i=1; i<=nlstate;i++){
                   7047:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7048:         } /* i */
                   7049:        } /* end bad */
                   7050:      }/* age */
                   7051:      sum=0.;
                   7052:      for (i=1; i<=nlstate;i++){
                   7053:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7054:      }
                   7055:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7056:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7057:        /* for (i=1; i<=nlstate;i++){ */
                   7058:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7059:        /* } /\* i *\/ */
                   7060:      } /* end bad */
                   7061:                
                   7062:      for (age=bage; age<=fage; age++){
1.235     brouard  7063:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7064:        sumnewp[cptcod]=0.;
                   7065:        sumnewm[cptcod]=0.;
                   7066:        for (i=1; i<=nlstate;i++){
                   7067:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7068:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7069:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7070:        }
                   7071:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7072:      }
                   7073:      /* printf("\n"); */
                   7074:      /* } */
                   7075:      /* brutal averaging */
                   7076:      for (i=1; i<=nlstate;i++){
                   7077:        for (age=1; age<=bage; age++){
                   7078:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7079:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7080:        }       
                   7081:        for (age=fage; age<=AGESUP; age++){
                   7082:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7083:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7084:        }
                   7085:      } /* end i status */
                   7086:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7087:        for (age=1; age<=AGESUP; age++){
                   7088:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7089:         mobaverage[(int)age][i][cptcod]=0.;
                   7090:        }
                   7091:      }
                   7092:    }/* end cptcod */
                   7093:    free_vector(sumnewm,1, ncovcombmax);
                   7094:    free_vector(sumnewp,1, ncovcombmax);
                   7095:    free_vector(agemaxgood,1, ncovcombmax);
                   7096:    free_vector(agemingood,1, ncovcombmax);
                   7097:    return 0;
                   7098:  }/* End movingaverage */
1.218     brouard  7099:  
1.126     brouard  7100: 
                   7101: /************** Forecasting ******************/
1.235     brouard  7102:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7103:   /* proj1, year, month, day of starting projection 
                   7104:      agemin, agemax range of age
                   7105:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7106:      anproj2 year of en of projection (same day and month as proj1).
                   7107:   */
1.235     brouard  7108:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7109:   double agec; /* generic age */
                   7110:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7111:   double *popeffectif,*popcount;
                   7112:   double ***p3mat;
1.218     brouard  7113:   /* double ***mobaverage; */
1.126     brouard  7114:   char fileresf[FILENAMELENGTH];
                   7115: 
                   7116:   agelim=AGESUP;
1.211     brouard  7117:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7118:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7119:      We still use firstpass and lastpass as another selection.
                   7120:   */
1.214     brouard  7121:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7122:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7123:  
1.201     brouard  7124:   strcpy(fileresf,"F_"); 
                   7125:   strcat(fileresf,fileresu);
1.126     brouard  7126:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7127:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7128:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7129:   }
1.235     brouard  7130:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7131:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7132: 
1.225     brouard  7133:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7134: 
                   7135: 
                   7136:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7137:   if (stepm<=12) stepsize=1;
                   7138:   if(estepm < stepm){
                   7139:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7140:   }
                   7141:   else  hstepm=estepm;   
                   7142: 
                   7143:   hstepm=hstepm/stepm; 
                   7144:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7145:                                fractional in yp1 */
                   7146:   anprojmean=yp;
                   7147:   yp2=modf((yp1*12),&yp);
                   7148:   mprojmean=yp;
                   7149:   yp1=modf((yp2*30.5),&yp);
                   7150:   jprojmean=yp;
                   7151:   if(jprojmean==0) jprojmean=1;
                   7152:   if(mprojmean==0) jprojmean=1;
                   7153: 
1.227     brouard  7154:   i1=pow(2,cptcoveff);
1.126     brouard  7155:   if (cptcovn < 1){i1=1;}
                   7156:   
                   7157:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7158:   
                   7159:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7160:   
1.126     brouard  7161: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7162:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7163:   for(k=1; k<=i1;k++){
                   7164:     if(TKresult[nres]!= k)
                   7165:       continue;
1.227     brouard  7166:     if(invalidvarcomb[k]){
                   7167:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7168:       continue;
                   7169:     }
                   7170:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7171:     for(j=1;j<=cptcoveff;j++) {
                   7172:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7173:     }
1.235     brouard  7174:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7175:       printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7176:       fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7177:     }
1.227     brouard  7178:     fprintf(ficresf," yearproj age");
                   7179:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7180:       for(i=1; i<=nlstate;i++)               
                   7181:        fprintf(ficresf," p%d%d",i,j);
                   7182:       fprintf(ficresf," wp.%d",j);
                   7183:     }
                   7184:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7185:       fprintf(ficresf,"\n");
                   7186:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7187:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7188:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7189:        nhstepm = nhstepm/hstepm; 
                   7190:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7191:        oldm=oldms;savm=savms;
1.235     brouard  7192:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7193:        
                   7194:        for (h=0; h<=nhstepm; h++){
                   7195:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7196:            fprintf(ficresf,"\n");
                   7197:            for(j=1;j<=cptcoveff;j++) 
                   7198:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7199:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7200:          } 
                   7201:          for(j=1; j<=nlstate+ndeath;j++) {
                   7202:            ppij=0.;
                   7203:            for(i=1; i<=nlstate;i++) {
                   7204:              if (mobilav==1) 
                   7205:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7206:              else {
                   7207:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7208:              }
                   7209:              if (h*hstepm/YEARM*stepm== yearp) {
                   7210:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7211:              }
                   7212:            } /* end i */
                   7213:            if (h*hstepm/YEARM*stepm==yearp) {
                   7214:              fprintf(ficresf," %.3f", ppij);
                   7215:            }
                   7216:          }/* end j */
                   7217:        } /* end h */
                   7218:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7219:       } /* end agec */
                   7220:     } /* end yearp */
                   7221:   } /* end  k */
1.219     brouard  7222:        
1.126     brouard  7223:   fclose(ficresf);
1.215     brouard  7224:   printf("End of Computing forecasting \n");
                   7225:   fprintf(ficlog,"End of Computing forecasting\n");
                   7226: 
1.126     brouard  7227: }
                   7228: 
1.218     brouard  7229: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7230: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7231: /*   /\* back1, year, month, day of starting backection  */
                   7232: /*      agemin, agemax range of age */
                   7233: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7234: /*      anback2 year of en of backection (same day and month as back1). */
                   7235: /*   *\/ */
                   7236: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7237: /*   double agec; /\* generic age *\/ */
                   7238: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7239: /*   double *popeffectif,*popcount; */
                   7240: /*   double ***p3mat; */
                   7241: /*   /\* double ***mobaverage; *\/ */
                   7242: /*   char fileresfb[FILENAMELENGTH]; */
                   7243:        
                   7244: /*   agelim=AGESUP; */
                   7245: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7246: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7247: /*      We still use firstpass and lastpass as another selection. */
                   7248: /*   *\/ */
                   7249: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7250: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7251: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7252:        
                   7253: /*   strcpy(fileresfb,"FB_");  */
                   7254: /*   strcat(fileresfb,fileresu); */
                   7255: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7256: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7257: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7258: /*   } */
                   7259: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7260: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7261:        
1.225     brouard  7262: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7263:        
                   7264: /*   /\* if (mobilav!=0) { *\/ */
                   7265: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7266: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7267: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7268: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7269: /*   /\*   } *\/ */
                   7270: /*   /\* } *\/ */
                   7271:        
                   7272: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7273: /*   if (stepm<=12) stepsize=1; */
                   7274: /*   if(estepm < stepm){ */
                   7275: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7276: /*   } */
                   7277: /*   else  hstepm=estepm;    */
                   7278:        
                   7279: /*   hstepm=hstepm/stepm;  */
                   7280: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7281: /*                                fractional in yp1 *\/ */
                   7282: /*   anprojmean=yp; */
                   7283: /*   yp2=modf((yp1*12),&yp); */
                   7284: /*   mprojmean=yp; */
                   7285: /*   yp1=modf((yp2*30.5),&yp); */
                   7286: /*   jprojmean=yp; */
                   7287: /*   if(jprojmean==0) jprojmean=1; */
                   7288: /*   if(mprojmean==0) jprojmean=1; */
                   7289:        
1.225     brouard  7290: /*   i1=cptcoveff; */
1.218     brouard  7291: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7292:   
1.218     brouard  7293: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7294:   
1.218     brouard  7295: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7296:        
                   7297: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7298: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7299: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7300: /*       k=k+1; */
                   7301: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7302: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7303: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7304: /*       } */
                   7305: /*       fprintf(ficresfb," yearbproj age"); */
                   7306: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7307: /*                             for(i=1; i<=nlstate;i++)               */
                   7308: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7309: /*                             fprintf(ficresfb," p.%d",j); */
                   7310: /*       } */
                   7311: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7312: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7313: /*                             fprintf(ficresfb,"\n"); */
                   7314: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7315: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7316: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7317: /*                                     nhstepm = nhstepm/hstepm;  */
                   7318: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7319: /*                                     oldm=oldms;savm=savms; */
                   7320: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7321: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7322: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7323: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7324: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7325: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7326: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7327: /*                                             }  */
                   7328: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7329: /*                                                     ppij=0.; */
                   7330: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7331: /*                                                             if (mobilav==1)  */
                   7332: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7333: /*                                                             else { */
                   7334: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7335: /*                                                             } */
                   7336: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7337: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7338: /*                                                             } */
                   7339: /*                                                     } /\* end i *\/ */
                   7340: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7341: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7342: /*                                                     } */
                   7343: /*                                             }/\* end j *\/ */
                   7344: /*                                     } /\* end h *\/ */
                   7345: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7346: /*                             } /\* end agec *\/ */
                   7347: /*       } /\* end yearp *\/ */
                   7348: /*     } /\* end cptcod *\/ */
                   7349: /*   } /\* end  cptcov *\/ */
                   7350:        
                   7351: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7352:        
                   7353: /*   fclose(ficresfb); */
                   7354: /*   printf("End of Computing Back forecasting \n"); */
                   7355: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7356:        
1.218     brouard  7357: /* } */
1.217     brouard  7358: 
1.126     brouard  7359: /************** Forecasting *****not tested NB*************/
1.227     brouard  7360: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7361:   
1.227     brouard  7362: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7363: /*   int *popage; */
                   7364: /*   double calagedatem, agelim, kk1, kk2; */
                   7365: /*   double *popeffectif,*popcount; */
                   7366: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7367: /*   /\* double ***mobaverage; *\/ */
                   7368: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7369: 
1.227     brouard  7370: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7371: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7372: /*   agelim=AGESUP; */
                   7373: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7374:   
1.227     brouard  7375: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7376:   
                   7377:   
1.227     brouard  7378: /*   strcpy(filerespop,"POP_");  */
                   7379: /*   strcat(filerespop,fileresu); */
                   7380: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7381: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7382: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7383: /*   } */
                   7384: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7385: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7386: 
1.227     brouard  7387: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7388: 
1.227     brouard  7389: /*   /\* if (mobilav!=0) { *\/ */
                   7390: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7391: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7392: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7393: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7394: /*   /\*   } *\/ */
                   7395: /*   /\* } *\/ */
1.126     brouard  7396: 
1.227     brouard  7397: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7398: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7399:   
1.227     brouard  7400: /*   agelim=AGESUP; */
1.126     brouard  7401:   
1.227     brouard  7402: /*   hstepm=1; */
                   7403: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7404:        
1.227     brouard  7405: /*   if (popforecast==1) { */
                   7406: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7407: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7408: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7409: /*     }  */
                   7410: /*     popage=ivector(0,AGESUP); */
                   7411: /*     popeffectif=vector(0,AGESUP); */
                   7412: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7413:     
1.227     brouard  7414: /*     i=1;    */
                   7415: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7416:     
1.227     brouard  7417: /*     imx=i; */
                   7418: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7419: /*   } */
1.218     brouard  7420:   
1.227     brouard  7421: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7422: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7423: /*       k=k+1; */
                   7424: /*       fprintf(ficrespop,"\n#******"); */
                   7425: /*       for(j=1;j<=cptcoveff;j++) { */
                   7426: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7427: /*       } */
                   7428: /*       fprintf(ficrespop,"******\n"); */
                   7429: /*       fprintf(ficrespop,"# Age"); */
                   7430: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7431: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7432:       
1.227     brouard  7433: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7434: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7435:        
1.227     brouard  7436: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7437: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7438: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7439:          
1.227     brouard  7440: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7441: /*       oldm=oldms;savm=savms; */
                   7442: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7443:          
1.227     brouard  7444: /*       for (h=0; h<=nhstepm; h++){ */
                   7445: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7446: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7447: /*         }  */
                   7448: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7449: /*           kk1=0.;kk2=0; */
                   7450: /*           for(i=1; i<=nlstate;i++) {               */
                   7451: /*             if (mobilav==1)  */
                   7452: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7453: /*             else { */
                   7454: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7455: /*             } */
                   7456: /*           } */
                   7457: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7458: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7459: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7460: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7461: /*           } */
                   7462: /*         } */
                   7463: /*         for(i=1; i<=nlstate;i++){ */
                   7464: /*           kk1=0.; */
                   7465: /*           for(j=1; j<=nlstate;j++){ */
                   7466: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7467: /*           } */
                   7468: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7469: /*         } */
1.218     brouard  7470:            
1.227     brouard  7471: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7472: /*           for(j=1; j<=nlstate;j++)  */
                   7473: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7474: /*       } */
                   7475: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7476: /*     } */
                   7477: /*       } */
1.218     brouard  7478:       
1.227     brouard  7479: /*       /\******\/ */
1.218     brouard  7480:       
1.227     brouard  7481: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7482: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7483: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7484: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7485: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7486:          
1.227     brouard  7487: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7488: /*       oldm=oldms;savm=savms; */
                   7489: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7490: /*       for (h=0; h<=nhstepm; h++){ */
                   7491: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7492: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7493: /*         }  */
                   7494: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7495: /*           kk1=0.;kk2=0; */
                   7496: /*           for(i=1; i<=nlstate;i++) {               */
                   7497: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7498: /*           } */
                   7499: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7500: /*         } */
                   7501: /*       } */
                   7502: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7503: /*     } */
                   7504: /*       } */
                   7505: /*     }  */
                   7506: /*   } */
1.218     brouard  7507:   
1.227     brouard  7508: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7509:   
1.227     brouard  7510: /*   if (popforecast==1) { */
                   7511: /*     free_ivector(popage,0,AGESUP); */
                   7512: /*     free_vector(popeffectif,0,AGESUP); */
                   7513: /*     free_vector(popcount,0,AGESUP); */
                   7514: /*   } */
                   7515: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7516: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7517: /*   fclose(ficrespop); */
                   7518: /* } /\* End of popforecast *\/ */
1.218     brouard  7519:  
1.126     brouard  7520: int fileappend(FILE *fichier, char *optionfich)
                   7521: {
                   7522:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7523:     printf("Problem with file: %s\n", optionfich);
                   7524:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7525:     return (0);
                   7526:   }
                   7527:   fflush(fichier);
                   7528:   return (1);
                   7529: }
                   7530: 
                   7531: 
                   7532: /**************** function prwizard **********************/
                   7533: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7534: {
                   7535: 
                   7536:   /* Wizard to print covariance matrix template */
                   7537: 
1.164     brouard  7538:   char ca[32], cb[32];
                   7539:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7540:   int numlinepar;
                   7541: 
                   7542:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7543:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7544:   for(i=1; i <=nlstate; i++){
                   7545:     jj=0;
                   7546:     for(j=1; j <=nlstate+ndeath; j++){
                   7547:       if(j==i) continue;
                   7548:       jj++;
                   7549:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7550:       printf("%1d%1d",i,j);
                   7551:       fprintf(ficparo,"%1d%1d",i,j);
                   7552:       for(k=1; k<=ncovmodel;k++){
                   7553:        /*        printf(" %lf",param[i][j][k]); */
                   7554:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7555:        printf(" 0.");
                   7556:        fprintf(ficparo," 0.");
                   7557:       }
                   7558:       printf("\n");
                   7559:       fprintf(ficparo,"\n");
                   7560:     }
                   7561:   }
                   7562:   printf("# Scales (for hessian or gradient estimation)\n");
                   7563:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7564:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7565:   for(i=1; i <=nlstate; i++){
                   7566:     jj=0;
                   7567:     for(j=1; j <=nlstate+ndeath; j++){
                   7568:       if(j==i) continue;
                   7569:       jj++;
                   7570:       fprintf(ficparo,"%1d%1d",i,j);
                   7571:       printf("%1d%1d",i,j);
                   7572:       fflush(stdout);
                   7573:       for(k=1; k<=ncovmodel;k++){
                   7574:        /*      printf(" %le",delti3[i][j][k]); */
                   7575:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7576:        printf(" 0.");
                   7577:        fprintf(ficparo," 0.");
                   7578:       }
                   7579:       numlinepar++;
                   7580:       printf("\n");
                   7581:       fprintf(ficparo,"\n");
                   7582:     }
                   7583:   }
                   7584:   printf("# Covariance matrix\n");
                   7585: /* # 121 Var(a12)\n\ */
                   7586: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7587: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7588: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7589: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7590: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7591: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7592: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7593:   fflush(stdout);
                   7594:   fprintf(ficparo,"# Covariance matrix\n");
                   7595:   /* # 121 Var(a12)\n\ */
                   7596:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7597:   /* #   ...\n\ */
                   7598:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7599:   
                   7600:   for(itimes=1;itimes<=2;itimes++){
                   7601:     jj=0;
                   7602:     for(i=1; i <=nlstate; i++){
                   7603:       for(j=1; j <=nlstate+ndeath; j++){
                   7604:        if(j==i) continue;
                   7605:        for(k=1; k<=ncovmodel;k++){
                   7606:          jj++;
                   7607:          ca[0]= k+'a'-1;ca[1]='\0';
                   7608:          if(itimes==1){
                   7609:            printf("#%1d%1d%d",i,j,k);
                   7610:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7611:          }else{
                   7612:            printf("%1d%1d%d",i,j,k);
                   7613:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7614:            /*  printf(" %.5le",matcov[i][j]); */
                   7615:          }
                   7616:          ll=0;
                   7617:          for(li=1;li <=nlstate; li++){
                   7618:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7619:              if(lj==li) continue;
                   7620:              for(lk=1;lk<=ncovmodel;lk++){
                   7621:                ll++;
                   7622:                if(ll<=jj){
                   7623:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7624:                  if(ll<jj){
                   7625:                    if(itimes==1){
                   7626:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7627:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7628:                    }else{
                   7629:                      printf(" 0.");
                   7630:                      fprintf(ficparo," 0.");
                   7631:                    }
                   7632:                  }else{
                   7633:                    if(itimes==1){
                   7634:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   7635:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   7636:                    }else{
                   7637:                      printf(" 0.");
                   7638:                      fprintf(ficparo," 0.");
                   7639:                    }
                   7640:                  }
                   7641:                }
                   7642:              } /* end lk */
                   7643:            } /* end lj */
                   7644:          } /* end li */
                   7645:          printf("\n");
                   7646:          fprintf(ficparo,"\n");
                   7647:          numlinepar++;
                   7648:        } /* end k*/
                   7649:       } /*end j */
                   7650:     } /* end i */
                   7651:   } /* end itimes */
                   7652: 
                   7653: } /* end of prwizard */
                   7654: /******************* Gompertz Likelihood ******************************/
                   7655: double gompertz(double x[])
                   7656: { 
                   7657:   double A,B,L=0.0,sump=0.,num=0.;
                   7658:   int i,n=0; /* n is the size of the sample */
                   7659: 
1.220     brouard  7660:   for (i=1;i<=imx ; i++) {
1.126     brouard  7661:     sump=sump+weight[i];
                   7662:     /*    sump=sump+1;*/
                   7663:     num=num+1;
                   7664:   }
                   7665:  
                   7666:  
                   7667:   /* for (i=0; i<=imx; i++) 
                   7668:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7669: 
                   7670:   for (i=1;i<=imx ; i++)
                   7671:     {
                   7672:       if (cens[i] == 1 && wav[i]>1)
                   7673:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   7674:       
                   7675:       if (cens[i] == 0 && wav[i]>1)
                   7676:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   7677:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   7678:       
                   7679:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7680:       if (wav[i] > 1 ) { /* ??? */
                   7681:        L=L+A*weight[i];
                   7682:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7683:       }
                   7684:     }
                   7685: 
                   7686:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7687:  
                   7688:   return -2*L*num/sump;
                   7689: }
                   7690: 
1.136     brouard  7691: #ifdef GSL
                   7692: /******************* Gompertz_f Likelihood ******************************/
                   7693: double gompertz_f(const gsl_vector *v, void *params)
                   7694: { 
                   7695:   double A,B,LL=0.0,sump=0.,num=0.;
                   7696:   double *x= (double *) v->data;
                   7697:   int i,n=0; /* n is the size of the sample */
                   7698: 
                   7699:   for (i=0;i<=imx-1 ; i++) {
                   7700:     sump=sump+weight[i];
                   7701:     /*    sump=sump+1;*/
                   7702:     num=num+1;
                   7703:   }
                   7704:  
                   7705:  
                   7706:   /* for (i=0; i<=imx; i++) 
                   7707:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   7708:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   7709:   for (i=1;i<=imx ; i++)
                   7710:     {
                   7711:       if (cens[i] == 1 && wav[i]>1)
                   7712:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   7713:       
                   7714:       if (cens[i] == 0 && wav[i]>1)
                   7715:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   7716:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   7717:       
                   7718:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   7719:       if (wav[i] > 1 ) { /* ??? */
                   7720:        LL=LL+A*weight[i];
                   7721:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   7722:       }
                   7723:     }
                   7724: 
                   7725:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   7726:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   7727:  
                   7728:   return -2*LL*num/sump;
                   7729: }
                   7730: #endif
                   7731: 
1.126     brouard  7732: /******************* Printing html file ***********/
1.201     brouard  7733: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  7734:                  int lastpass, int stepm, int weightopt, char model[],\
                   7735:                  int imx,  double p[],double **matcov,double agemortsup){
                   7736:   int i,k;
                   7737: 
                   7738:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   7739:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   7740:   for (i=1;i<=2;i++) 
                   7741:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  7742:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  7743:   fprintf(fichtm,"</ul>");
                   7744: 
                   7745: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   7746: 
                   7747:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   7748: 
                   7749:  for (k=agegomp;k<(agemortsup-2);k++) 
                   7750:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   7751: 
                   7752:  
                   7753:   fflush(fichtm);
                   7754: }
                   7755: 
                   7756: /******************* Gnuplot file **************/
1.201     brouard  7757: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  7758: 
                   7759:   char dirfileres[132],optfileres[132];
1.164     brouard  7760: 
1.126     brouard  7761:   int ng;
                   7762: 
                   7763: 
                   7764:   /*#ifdef windows */
                   7765:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   7766:     /*#endif */
                   7767: 
                   7768: 
                   7769:   strcpy(dirfileres,optionfilefiname);
                   7770:   strcpy(optfileres,"vpl");
1.199     brouard  7771:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  7772:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  7773:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  7774:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  7775:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   7776: 
                   7777: } 
                   7778: 
1.136     brouard  7779: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   7780: {
1.126     brouard  7781: 
1.136     brouard  7782:   /*-------- data file ----------*/
                   7783:   FILE *fic;
                   7784:   char dummy[]="                         ";
1.223     brouard  7785:   int i=0, j=0, n=0, iv=0;
                   7786:   int lstra;
1.136     brouard  7787:   int linei, month, year,iout;
                   7788:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  7789:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  7790:   char *stratrunc;
1.223     brouard  7791: 
1.126     brouard  7792: 
                   7793: 
1.136     brouard  7794:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  7795:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   7796:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  7797:   }
1.126     brouard  7798: 
1.136     brouard  7799:   i=1;
                   7800:   linei=0;
                   7801:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   7802:     linei=linei+1;
                   7803:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   7804:       if(line[j] == '\t')
                   7805:        line[j] = ' ';
                   7806:     }
                   7807:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   7808:       ;
                   7809:     };
                   7810:     line[j+1]=0;  /* Trims blanks at end of line */
                   7811:     if(line[0]=='#'){
                   7812:       fprintf(ficlog,"Comment line\n%s\n",line);
                   7813:       printf("Comment line\n%s\n",line);
                   7814:       continue;
                   7815:     }
                   7816:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  7817:     strcpy(line, linetmp);
1.223     brouard  7818:     
                   7819:     /* Loops on waves */
                   7820:     for (j=maxwav;j>=1;j--){
                   7821:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.232     brouard  7822:                                cutv(stra, strb, line, ' '); 
                   7823:                                if(strb[0]=='.') { /* Missing value */
                   7824:                                        lval=-1;
                   7825:                                        cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   7826:                                        cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   7827:                                        if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   7828:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   7829:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   7830:                                                return 1;
                   7831:                                        }
                   7832:                                }else{
                   7833:                                        errno=0;
                   7834:                                        /* what_kind_of_number(strb); */
                   7835:                                        dval=strtod(strb,&endptr); 
                   7836:                                        /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   7837:                                        /* if(strb != endptr && *endptr == '\0') */
                   7838:                                        /*    dval=dlval; */
                   7839:                                        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7840:                                        if( strb[0]=='\0' || (*endptr != '\0')){
                   7841:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   7842:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   7843:                                                return 1;
                   7844:                                        }
                   7845:                                        cotqvar[j][iv][i]=dval; 
                   7846:                                        cotvar[j][ntv+iv][i]=dval; 
                   7847:                                }
                   7848:                                strcpy(line,stra);
1.223     brouard  7849:       }/* end loop ntqv */
1.225     brouard  7850:       
1.223     brouard  7851:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.232     brouard  7852:                                cutv(stra, strb, line, ' '); 
                   7853:                                if(strb[0]=='.') { /* Missing value */
                   7854:                                        lval=-1;
                   7855:                                }else{
                   7856:                                        errno=0;
                   7857:                                        lval=strtol(strb,&endptr,10); 
                   7858:                                        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7859:                                        if( strb[0]=='\0' || (*endptr != '\0')){
                   7860:                                                printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   7861:                                                fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   7862:                                                return 1;
                   7863:                                        }
                   7864:                                }
                   7865:                                if(lval <-1 || lval >1){
                   7866:                                        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  7867:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7868:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.232     brouard  7869:  For example, for multinomial values like 1, 2 and 3,\n                                                                        \
                   7870:  build V1=0 V2=0 for the reference value (1),\n                                                                                                        \
                   7871:         V1=1 V2=0 for (2) \n                                                                                                                                                                           \
1.223     brouard  7872:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.232     brouard  7873:  output of IMaCh is often meaningless.\n                                                                                                                               \
1.223     brouard  7874:  Exiting.\n",lval,linei, i,line,j);
1.232     brouard  7875:                                        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  7876:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   7877:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.232     brouard  7878:  For example, for multinomial values like 1, 2 and 3,\n                                                                        \
                   7879:  build V1=0 V2=0 for the reference value (1),\n                                                                                                        \
                   7880:         V1=1 V2=0 for (2) \n                                                                                                                                                                           \
1.223     brouard  7881:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.232     brouard  7882:  output of IMaCh is often meaningless.\n                                                                                                                               \
1.223     brouard  7883:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.232     brouard  7884:                                        return 1;
                   7885:                                }
                   7886:                                cotvar[j][iv][i]=(double)(lval);
                   7887:                                strcpy(line,stra);
1.223     brouard  7888:       }/* end loop ntv */
1.225     brouard  7889:       
1.223     brouard  7890:       /* Statuses  at wave */
1.137     brouard  7891:       cutv(stra, strb, line, ' '); 
1.223     brouard  7892:       if(strb[0]=='.') { /* Missing value */
1.232     brouard  7893:                                lval=-1;
1.136     brouard  7894:       }else{
1.232     brouard  7895:                                errno=0;
                   7896:                                lval=strtol(strb,&endptr,10); 
                   7897:                                /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   7898:                                if( strb[0]=='\0' || (*endptr != '\0')){
                   7899:                                        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   7900:                                        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   7901:                                        return 1;
                   7902:                                }
1.136     brouard  7903:       }
1.225     brouard  7904:       
1.136     brouard  7905:       s[j][i]=lval;
1.225     brouard  7906:       
1.223     brouard  7907:       /* Date of Interview */
1.136     brouard  7908:       strcpy(line,stra);
                   7909:       cutv(stra, strb,line,' ');
1.169     brouard  7910:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7911:       }
1.169     brouard  7912:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  7913:        month=99;
                   7914:        year=9999;
1.136     brouard  7915:       }else{
1.225     brouard  7916:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   7917:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   7918:        return 1;
1.136     brouard  7919:       }
                   7920:       anint[j][i]= (double) year; 
                   7921:       mint[j][i]= (double)month; 
                   7922:       strcpy(line,stra);
1.223     brouard  7923:     } /* End loop on waves */
1.225     brouard  7924:     
1.223     brouard  7925:     /* Date of death */
1.136     brouard  7926:     cutv(stra, strb,line,' '); 
1.169     brouard  7927:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7928:     }
1.169     brouard  7929:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  7930:       month=99;
                   7931:       year=9999;
                   7932:     }else{
1.141     brouard  7933:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  7934:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   7935:       return 1;
1.136     brouard  7936:     }
                   7937:     andc[i]=(double) year; 
                   7938:     moisdc[i]=(double) month; 
                   7939:     strcpy(line,stra);
                   7940:     
1.223     brouard  7941:     /* Date of birth */
1.136     brouard  7942:     cutv(stra, strb,line,' '); 
1.169     brouard  7943:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  7944:     }
1.169     brouard  7945:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  7946:       month=99;
                   7947:       year=9999;
                   7948:     }else{
1.141     brouard  7949:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   7950:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  7951:       return 1;
1.136     brouard  7952:     }
                   7953:     if (year==9999) {
1.141     brouard  7954:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   7955:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  7956:       return 1;
                   7957:       
1.136     brouard  7958:     }
                   7959:     annais[i]=(double)(year);
                   7960:     moisnais[i]=(double)(month); 
                   7961:     strcpy(line,stra);
1.225     brouard  7962:     
1.223     brouard  7963:     /* Sample weight */
1.136     brouard  7964:     cutv(stra, strb,line,' '); 
                   7965:     errno=0;
                   7966:     dval=strtod(strb,&endptr); 
                   7967:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  7968:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   7969:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  7970:       fflush(ficlog);
                   7971:       return 1;
                   7972:     }
                   7973:     weight[i]=dval; 
                   7974:     strcpy(line,stra);
1.225     brouard  7975:     
1.223     brouard  7976:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   7977:       cutv(stra, strb, line, ' '); 
                   7978:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  7979:        lval=-1;
1.223     brouard  7980:       }else{
1.225     brouard  7981:        errno=0;
                   7982:        /* what_kind_of_number(strb); */
                   7983:        dval=strtod(strb,&endptr);
                   7984:        /* if(strb != endptr && *endptr == '\0') */
                   7985:        /*   dval=dlval; */
                   7986:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   7987:        if( strb[0]=='\0' || (*endptr != '\0')){
                   7988:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   7989:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   7990:          return 1;
                   7991:        }
                   7992:        coqvar[iv][i]=dval; 
1.226     brouard  7993:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  7994:       }
                   7995:       strcpy(line,stra);
                   7996:     }/* end loop nqv */
1.136     brouard  7997:     
1.223     brouard  7998:     /* Covariate values */
1.136     brouard  7999:     for (j=ncovcol;j>=1;j--){
                   8000:       cutv(stra, strb,line,' '); 
1.223     brouard  8001:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8002:        lval=-1;
1.136     brouard  8003:       }else{
1.225     brouard  8004:        errno=0;
                   8005:        lval=strtol(strb,&endptr,10); 
                   8006:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8007:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8008:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8009:          return 1;
                   8010:        }
1.136     brouard  8011:       }
                   8012:       if(lval <-1 || lval >1){
1.225     brouard  8013:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8014:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8015:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8016:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8017:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8018:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8019:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8020:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8021:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8022:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8023:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8024:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8025:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8026:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8027:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8028:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8029:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8030:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8031:        return 1;
1.136     brouard  8032:       }
                   8033:       covar[j][i]=(double)(lval);
                   8034:       strcpy(line,stra);
                   8035:     }  
                   8036:     lstra=strlen(stra);
1.225     brouard  8037:     
1.136     brouard  8038:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8039:       stratrunc = &(stra[lstra-9]);
                   8040:       num[i]=atol(stratrunc);
                   8041:     }
                   8042:     else
                   8043:       num[i]=atol(stra);
                   8044:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8045:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8046:     
                   8047:     i=i+1;
                   8048:   } /* End loop reading  data */
1.225     brouard  8049:   
1.136     brouard  8050:   *imax=i-1; /* Number of individuals */
                   8051:   fclose(fic);
1.225     brouard  8052:   
1.136     brouard  8053:   return (0);
1.164     brouard  8054:   /* endread: */
1.225     brouard  8055:   printf("Exiting readdata: ");
                   8056:   fclose(fic);
                   8057:   return (1);
1.223     brouard  8058: }
1.126     brouard  8059: 
1.234     brouard  8060: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8061:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8062:   while (*p2 == ' ')
1.234     brouard  8063:     p2++; 
                   8064:   /* while ((*p1++ = *p2++) !=0) */
                   8065:   /*   ; */
                   8066:   /* do */
                   8067:   /*   while (*p2 == ' ') */
                   8068:   /*     p2++; */
                   8069:   /* while (*p1++ == *p2++); */
                   8070:   *stri=p2; 
1.145     brouard  8071: }
                   8072: 
1.235     brouard  8073: int decoderesult ( char resultline[], int nres)
1.230     brouard  8074: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8075: {
1.235     brouard  8076:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8077:   char resultsav[MAXLINE];
1.234     brouard  8078:   int resultmodel[MAXLINE];
                   8079:   int modelresult[MAXLINE];
1.230     brouard  8080:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8081: 
1.234     brouard  8082:   removefirstspace(&resultline);
1.233     brouard  8083:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8084: 
                   8085:   if (strstr(resultline,"v") !=0){
                   8086:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8087:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8088:     return 1;
                   8089:   }
                   8090:   trimbb(resultsav, resultline);
                   8091:   if (strlen(resultsav) >1){
                   8092:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8093:   }
1.234     brouard  8094:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8095:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8096:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8097:   }
                   8098:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8099:     if(nbocc(resultsav,'=') >1){
                   8100:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8101:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8102:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8103:     }else
                   8104:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8105:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8106:     
1.230     brouard  8107:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8108:     Tvarsel[k]=atoi(strc);
                   8109:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8110:     /* cptcovsel++;     */
                   8111:     if (nbocc(stra,'=') >0)
                   8112:       strcpy(resultsav,stra); /* and analyzes it */
                   8113:   }
1.235     brouard  8114:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8115:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8116:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8117:       match=0;
1.236     brouard  8118:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237   ! brouard  8119:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8120:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8121:          match=1;
                   8122:          break;
                   8123:        }
                   8124:       }
                   8125:       if(match == 0){
                   8126:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8127:       }
                   8128:     }
                   8129:   }
1.235     brouard  8130:   /* Checking for missing or useless values in comparison of current model needs */
                   8131:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8132:     match=0;
1.235     brouard  8133:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8134:       if(Typevar[k1]==0){ /* Single */
1.237   ! brouard  8135:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8136:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8137:          ++match;
                   8138:        }
                   8139:       }
                   8140:     }
                   8141:     if(match == 0){
                   8142:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8143:     }else if(match > 1){
                   8144:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8145:     }
                   8146:   }
1.235     brouard  8147:       
1.234     brouard  8148:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8149:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8150:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8151:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8152:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8153:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8154:   /*    1 0 0 0 */
                   8155:   /*    2 1 0 0 */
                   8156:   /*    3 0 1 0 */ 
                   8157:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8158:   /*    5 0 0 1 */
                   8159:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8160:   /*    7 0 1 1 */
                   8161:   /*    8 1 1 1 */
1.237   ! brouard  8162:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
        !          8163:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
        !          8164:   /* V5*age V5 known which value for nres?  */
        !          8165:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8166:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8167:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237   ! brouard  8168:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8169:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8170:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237   ! brouard  8171:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
        !          8172:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
        !          8173:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8174:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8175:       k4++;;
                   8176:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8177:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8178:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237   ! brouard  8179:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
        !          8180:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
        !          8181:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8182:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8183:       k4q++;;
                   8184:     }
                   8185:   }
1.234     brouard  8186:   
1.235     brouard  8187:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8188:   return (0);
                   8189: }
1.235     brouard  8190: 
1.230     brouard  8191: int decodemodel( char model[], int lastobs)
                   8192:  /**< This routine decodes the model and returns:
1.224     brouard  8193:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8194:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8195:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8196:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8197:        * - cptcovage number of covariates with age*products =2
                   8198:        * - cptcovs number of simple covariates
                   8199:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8200:        *     which is a new column after the 9 (ncovcol) variables. 
                   8201:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8202:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8203:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8204:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8205:        */
1.136     brouard  8206: {
1.145     brouard  8207:   int i, j, k, ks;
1.227     brouard  8208:   int  j1, k1, k2, k3, k4;
1.136     brouard  8209:   char modelsav[80];
1.145     brouard  8210:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8211:   char *strpt;
1.136     brouard  8212: 
1.145     brouard  8213:   /*removespace(model);*/
1.136     brouard  8214:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8215:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8216:     if (strstr(model,"AGE") !=0){
1.192     brouard  8217:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8218:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8219:       return 1;
                   8220:     }
1.141     brouard  8221:     if (strstr(model,"v") !=0){
                   8222:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8223:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8224:       return 1;
                   8225:     }
1.187     brouard  8226:     strcpy(modelsav,model); 
                   8227:     if ((strpt=strstr(model,"age*age")) !=0){
                   8228:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8229:       if(strpt != model){
1.234     brouard  8230:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8231:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8232:  corresponding column of parameters.\n",model);
1.234     brouard  8233:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8234:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8235:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8236:        return 1;
1.225     brouard  8237:       }
1.187     brouard  8238:       nagesqr=1;
                   8239:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8240:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8241:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8242:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8243:       else 
1.234     brouard  8244:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8245:     }else
                   8246:       nagesqr=0;
                   8247:     if (strlen(modelsav) >1){
                   8248:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8249:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8250:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8251:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8252:                     * cst, age and age*age 
                   8253:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8254:       /* including age products which are counted in cptcovage.
                   8255:        * but the covariates which are products must be treated 
                   8256:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8257:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8258:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8259:       
                   8260:       
1.187     brouard  8261:       /*   Design
                   8262:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8263:        *  <          ncovcol=8                >
                   8264:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8265:        *   k=  1    2      3       4     5       6      7        8
                   8266:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8267:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8268:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8269:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8270:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8271:        *  Tage[++cptcovage]=k
                   8272:        *       if products, new covar are created after ncovcol with k1
                   8273:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8274:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8275:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8276:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8277:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8278:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8279:        *  <          ncovcol=8                >
                   8280:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8281:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8282:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8283:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8284:        * p Tprod[1]@2={                         6, 5}
                   8285:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8286:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8287:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8288:        *How to reorganize?
                   8289:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8290:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8291:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8292:        * Struct []
                   8293:        */
1.225     brouard  8294:       
1.187     brouard  8295:       /* This loop fills the array Tvar from the string 'model'.*/
                   8296:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8297:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8298:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8299:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8300:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8301:       /*       k=1 Tvar[1]=2 (from V2) */
                   8302:       /*       k=5 Tvar[5] */
                   8303:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8304:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8305:       /*       } */
1.198     brouard  8306:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8307:       /*
                   8308:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8309:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8310:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8311:       }
1.187     brouard  8312:       cptcovage=0;
                   8313:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8314:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8315:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8316:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8317:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8318:        /*scanf("%d",i);*/
                   8319:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8320:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8321:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8322:            /* covar is not filled and then is empty */
                   8323:            cptcovprod--;
                   8324:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8325:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8326:            Typevar[k]=1;  /* 1 for age product */
                   8327:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8328:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8329:            /*printf("stre=%s ", stre);*/
                   8330:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8331:            cptcovprod--;
                   8332:            cutl(stre,strb,strc,'V');
                   8333:            Tvar[k]=atoi(stre);
                   8334:            Typevar[k]=1;  /* 1 for age product */
                   8335:            cptcovage++;
                   8336:            Tage[cptcovage]=k;
                   8337:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8338:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8339:            cptcovn++;
                   8340:            cptcovprodnoage++;k1++;
                   8341:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8342:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8343:                                                because this model-covariate is a construction we invent a new column
                   8344:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8345:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8346:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8347:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8348:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8349:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8350:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8351:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8352:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8353:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8354:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8355:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8356:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8357:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8358:            for (i=1; i<=lastobs;i++){
                   8359:              /* Computes the new covariate which is a product of
                   8360:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8361:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8362:            }
                   8363:          } /* End age is not in the model */
                   8364:        } /* End if model includes a product */
                   8365:        else { /* no more sum */
                   8366:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8367:          /*  scanf("%d",i);*/
                   8368:          cutl(strd,strc,strb,'V');
                   8369:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8370:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8371:          Tvar[k]=atoi(strd);
                   8372:          Typevar[k]=0;  /* 0 for simple covariates */
                   8373:        }
                   8374:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8375:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8376:                                  scanf("%d",i);*/
1.187     brouard  8377:       } /* end of loop + on total covariates */
                   8378:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8379:   } /* end if strlen(model == 0) */
1.136     brouard  8380:   
                   8381:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8382:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8383:   
1.136     brouard  8384:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8385:      printf("cptcovprod=%d ", cptcovprod);
                   8386:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8387:      scanf("%d ",i);*/
                   8388: 
                   8389: 
1.230     brouard  8390: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8391:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8392: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8393:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8394:    k =           1    2   3     4       5       6      7      8        9
                   8395:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8396:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8397:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8398:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8399:          Tmodelind[combination of covar]=k;
1.225     brouard  8400: */  
                   8401: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8402:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8403:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8404:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8405:   printf("Model=%s\n\
                   8406: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8407: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8408: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8409:   fprintf(ficlog,"Model=%s\n\
                   8410: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8411: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8412: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8413: 
1.234     brouard  8414:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8415:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8416:       Fixed[k]= 0;
                   8417:       Dummy[k]= 0;
1.225     brouard  8418:       ncoveff++;
1.232     brouard  8419:       ncovf++;
1.234     brouard  8420:       nsd++;
                   8421:       modell[k].maintype= FTYPE;
                   8422:       TvarsD[nsd]=Tvar[k];
                   8423:       TvarsDind[nsd]=k;
                   8424:       TvarF[ncovf]=Tvar[k];
                   8425:       TvarFind[ncovf]=k;
                   8426:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8427:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8428:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8429:       Fixed[k]= 0;
                   8430:       Dummy[k]= 0;
                   8431:       ncoveff++;
                   8432:       ncovf++;
                   8433:       modell[k].maintype= FTYPE;
                   8434:       TvarF[ncovf]=Tvar[k];
                   8435:       TvarFind[ncovf]=k;
1.230     brouard  8436:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8437:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8438:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){ /* Remind that product Vn*Vm are added in k*/ /* Only simple fixed quantitative variable */
1.227     brouard  8439:       Fixed[k]= 0;
                   8440:       Dummy[k]= 1;
1.230     brouard  8441:       nqfveff++;
1.234     brouard  8442:       modell[k].maintype= FTYPE;
                   8443:       modell[k].subtype= FQ;
                   8444:       nsq++;
                   8445:       TvarsQ[nsq]=Tvar[k];
                   8446:       TvarsQind[nsq]=k;
1.232     brouard  8447:       ncovf++;
1.234     brouard  8448:       TvarF[ncovf]=Tvar[k];
                   8449:       TvarFind[ncovf]=k;
1.231     brouard  8450:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8451:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.234     brouard  8452:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying variables */
1.227     brouard  8453:       Fixed[k]= 1;
                   8454:       Dummy[k]= 0;
1.225     brouard  8455:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8456:       modell[k].maintype= VTYPE;
                   8457:       modell[k].subtype= VD;
                   8458:       nsd++;
                   8459:       TvarsD[nsd]=Tvar[k];
                   8460:       TvarsDind[nsd]=k;
                   8461:       ncovv++; /* Only simple time varying variables */
                   8462:       TvarV[ncovv]=Tvar[k];
                   8463:       TvarVind[ncovv]=k;
1.231     brouard  8464:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8465:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8466:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8467:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8468:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8469:       Fixed[k]= 1;
                   8470:       Dummy[k]= 1;
                   8471:       nqtveff++;
                   8472:       modell[k].maintype= VTYPE;
                   8473:       modell[k].subtype= VQ;
                   8474:       ncovv++; /* Only simple time varying variables */
                   8475:       nsq++;
                   8476:       TvarsQ[nsq]=Tvar[k];
                   8477:       TvarsQind[nsq]=k;
                   8478:       TvarV[ncovv]=Tvar[k];
                   8479:       TvarVind[ncovv]=k;
1.231     brouard  8480:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8481:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8482:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8483:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8484:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8485:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8486:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8487:       ncova++;
                   8488:       TvarA[ncova]=Tvar[k];
                   8489:       TvarAind[ncova]=k;
1.231     brouard  8490:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.234     brouard  8491:        Fixed[k]= 2;
                   8492:        Dummy[k]= 2;
                   8493:        modell[k].maintype= ATYPE;
                   8494:        modell[k].subtype= APFD;
                   8495:        /* ncoveff++; */
1.227     brouard  8496:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.234     brouard  8497:        Fixed[k]= 2;
                   8498:        Dummy[k]= 3;
                   8499:        modell[k].maintype= ATYPE;
                   8500:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8501:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8502:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.234     brouard  8503:        Fixed[k]= 3;
                   8504:        Dummy[k]= 2;
                   8505:        modell[k].maintype= ATYPE;
                   8506:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8507:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8508:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.234     brouard  8509:        Fixed[k]= 3;
                   8510:        Dummy[k]= 3;
                   8511:        modell[k].maintype= ATYPE;
                   8512:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8513:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8514:       }
                   8515:     }else if (Typevar[k] == 2) {  /* product without age */
                   8516:       k1=Tposprod[k];
                   8517:       if(Tvard[k1][1] <=ncovcol){
1.234     brouard  8518:        if(Tvard[k1][2] <=ncovcol){
                   8519:          Fixed[k]= 1;
                   8520:          Dummy[k]= 0;
                   8521:          modell[k].maintype= FTYPE;
                   8522:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8523:          ncovf++; /* Fixed variables without age */
                   8524:          TvarF[ncovf]=Tvar[k];
                   8525:          TvarFind[ncovf]=k;
                   8526:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8527:          Fixed[k]= 0;  /* or 2 ?*/
                   8528:          Dummy[k]= 1;
                   8529:          modell[k].maintype= FTYPE;
                   8530:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8531:          ncovf++; /* Varying variables without age */
                   8532:          TvarF[ncovf]=Tvar[k];
                   8533:          TvarFind[ncovf]=k;
                   8534:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8535:          Fixed[k]= 1;
                   8536:          Dummy[k]= 0;
                   8537:          modell[k].maintype= VTYPE;
                   8538:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8539:          ncovv++; /* Varying variables without age */
                   8540:          TvarV[ncovv]=Tvar[k];
                   8541:          TvarVind[ncovv]=k;
                   8542:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8543:          Fixed[k]= 1;
                   8544:          Dummy[k]= 1;
                   8545:          modell[k].maintype= VTYPE;
                   8546:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8547:          ncovv++; /* Varying variables without age */
                   8548:          TvarV[ncovv]=Tvar[k];
                   8549:          TvarVind[ncovv]=k;
                   8550:        } 
1.227     brouard  8551:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.234     brouard  8552:        if(Tvard[k1][2] <=ncovcol){
                   8553:          Fixed[k]= 0;  /* or 2 ?*/
                   8554:          Dummy[k]= 1;
                   8555:          modell[k].maintype= FTYPE;
                   8556:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8557:          ncovf++; /* Fixed variables without age */
                   8558:          TvarF[ncovf]=Tvar[k];
                   8559:          TvarFind[ncovf]=k;
                   8560:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8561:          Fixed[k]= 1;
                   8562:          Dummy[k]= 1;
                   8563:          modell[k].maintype= VTYPE;
                   8564:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8565:          ncovv++; /* Varying variables without age */
                   8566:          TvarV[ncovv]=Tvar[k];
                   8567:          TvarVind[ncovv]=k;
                   8568:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8569:          Fixed[k]= 1;
                   8570:          Dummy[k]= 1;
                   8571:          modell[k].maintype= VTYPE;
                   8572:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8573:          ncovv++; /* Varying variables without age */
                   8574:          TvarV[ncovv]=Tvar[k];
                   8575:          TvarVind[ncovv]=k;
                   8576:          ncovv++; /* Varying variables without age */
                   8577:          TvarV[ncovv]=Tvar[k];
                   8578:          TvarVind[ncovv]=k;
                   8579:        } 
1.227     brouard  8580:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.234     brouard  8581:        if(Tvard[k1][2] <=ncovcol){
                   8582:          Fixed[k]= 1;
                   8583:          Dummy[k]= 1;
                   8584:          modell[k].maintype= VTYPE;
                   8585:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8586:          ncovv++; /* Varying variables without age */
                   8587:          TvarV[ncovv]=Tvar[k];
                   8588:          TvarVind[ncovv]=k;
                   8589:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8590:          Fixed[k]= 1;
                   8591:          Dummy[k]= 1;
                   8592:          modell[k].maintype= VTYPE;
                   8593:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8594:          ncovv++; /* Varying variables without age */
                   8595:          TvarV[ncovv]=Tvar[k];
                   8596:          TvarVind[ncovv]=k;
                   8597:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8598:          Fixed[k]= 1;
                   8599:          Dummy[k]= 0;
                   8600:          modell[k].maintype= VTYPE;
                   8601:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   8602:          ncovv++; /* Varying variables without age */
                   8603:          TvarV[ncovv]=Tvar[k];
                   8604:          TvarVind[ncovv]=k;
                   8605:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8606:          Fixed[k]= 1;
                   8607:          Dummy[k]= 1;
                   8608:          modell[k].maintype= VTYPE;
                   8609:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   8610:          ncovv++; /* Varying variables without age */
                   8611:          TvarV[ncovv]=Tvar[k];
                   8612:          TvarVind[ncovv]=k;
                   8613:        } 
1.227     brouard  8614:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.234     brouard  8615:        if(Tvard[k1][2] <=ncovcol){
                   8616:          Fixed[k]= 1;
                   8617:          Dummy[k]= 1;
                   8618:          modell[k].maintype= VTYPE;
                   8619:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   8620:          ncovv++; /* Varying variables without age */
                   8621:          TvarV[ncovv]=Tvar[k];
                   8622:          TvarVind[ncovv]=k;
                   8623:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8624:          Fixed[k]= 1;
                   8625:          Dummy[k]= 1;
                   8626:          modell[k].maintype= VTYPE;
                   8627:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   8628:          ncovv++; /* Varying variables without age */
                   8629:          TvarV[ncovv]=Tvar[k];
                   8630:          TvarVind[ncovv]=k;
                   8631:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8632:          Fixed[k]= 1;
                   8633:          Dummy[k]= 1;
                   8634:          modell[k].maintype= VTYPE;
                   8635:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   8636:          ncovv++; /* Varying variables without age */
                   8637:          TvarV[ncovv]=Tvar[k];
                   8638:          TvarVind[ncovv]=k;
                   8639:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8640:          Fixed[k]= 1;
                   8641:          Dummy[k]= 1;
                   8642:          modell[k].maintype= VTYPE;
                   8643:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   8644:          ncovv++; /* Varying variables without age */
                   8645:          TvarV[ncovv]=Tvar[k];
                   8646:          TvarVind[ncovv]=k;
                   8647:        } 
1.227     brouard  8648:       }else{
1.234     brouard  8649:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   8650:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
1.226     brouard  8651:       } /* end k1 */
1.225     brouard  8652:     }else{
1.226     brouard  8653:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   8654:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  8655:     }
1.227     brouard  8656:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  8657:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  8658:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   8659:   }
                   8660:   /* Searching for doublons in the model */
                   8661:   for(k1=1; k1<= cptcovt;k1++){
                   8662:     for(k2=1; k2 <k1;k2++){
                   8663:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  8664:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   8665:          if(Tvar[k1]==Tvar[k2]){
                   8666:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8667:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8668:            return(1);
                   8669:          }
                   8670:        }else if (Typevar[k1] ==2){
                   8671:          k3=Tposprod[k1];
                   8672:          k4=Tposprod[k2];
                   8673:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   8674:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   8675:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   8676:            return(1);
                   8677:          }
                   8678:        }
1.227     brouard  8679:       }
                   8680:     }
1.225     brouard  8681:   }
                   8682:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   8683:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  8684:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   8685:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  8686:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  8687:   /*endread:*/
1.225     brouard  8688:   printf("Exiting decodemodel: ");
                   8689:   return (1);
1.136     brouard  8690: }
                   8691: 
1.169     brouard  8692: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.136     brouard  8693: {
                   8694:   int i, m;
1.218     brouard  8695:   int firstone=0;
                   8696:   
1.136     brouard  8697:   for (i=1; i<=imx; i++) {
                   8698:     for(m=2; (m<= maxwav); m++) {
                   8699:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   8700:        anint[m][i]=9999;
1.216     brouard  8701:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   8702:          s[m][i]=-1;
1.136     brouard  8703:       }
                   8704:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  8705:        *nberr = *nberr + 1;
1.218     brouard  8706:        if(firstone == 0){
                   8707:          firstone=1;
                   8708:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   8709:        }
                   8710:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  8711:        s[m][i]=-1;
                   8712:       }
                   8713:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  8714:        (*nberr)++;
1.136     brouard  8715:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   8716:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   8717:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   8718:       }
                   8719:     }
                   8720:   }
                   8721: 
                   8722:   for (i=1; i<=imx; i++)  {
                   8723:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   8724:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  8725:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  8726:        if (s[m][i] >= nlstate+1) {
1.169     brouard  8727:          if(agedc[i]>0){
                   8728:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  8729:              agev[m][i]=agedc[i];
1.214     brouard  8730:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  8731:            }else {
1.136     brouard  8732:              if ((int)andc[i]!=9999){
                   8733:                nbwarn++;
                   8734:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   8735:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   8736:                agev[m][i]=-1;
                   8737:              }
                   8738:            }
1.169     brouard  8739:          } /* agedc > 0 */
1.214     brouard  8740:        } /* end if */
1.136     brouard  8741:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   8742:                                 years but with the precision of a month */
                   8743:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   8744:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   8745:            agev[m][i]=1;
                   8746:          else if(agev[m][i] < *agemin){ 
                   8747:            *agemin=agev[m][i];
                   8748:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   8749:          }
                   8750:          else if(agev[m][i] >*agemax){
                   8751:            *agemax=agev[m][i];
1.156     brouard  8752:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  8753:          }
                   8754:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   8755:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  8756:        } /* en if 9*/
1.136     brouard  8757:        else { /* =9 */
1.214     brouard  8758:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  8759:          agev[m][i]=1;
                   8760:          s[m][i]=-1;
                   8761:        }
                   8762:       }
1.214     brouard  8763:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  8764:        agev[m][i]=1;
1.214     brouard  8765:       else{
                   8766:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8767:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   8768:        agev[m][i]=0;
                   8769:       }
                   8770:     } /* End for lastpass */
                   8771:   }
1.136     brouard  8772:     
                   8773:   for (i=1; i<=imx; i++)  {
                   8774:     for(m=firstpass; (m<=lastpass); m++){
                   8775:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  8776:        (*nberr)++;
1.136     brouard  8777:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8778:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   8779:        return 1;
                   8780:       }
                   8781:     }
                   8782:   }
                   8783: 
                   8784:   /*for (i=1; i<=imx; i++){
                   8785:   for (m=firstpass; (m<lastpass); m++){
                   8786:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   8787: }
                   8788: 
                   8789: }*/
                   8790: 
                   8791: 
1.139     brouard  8792:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   8793:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  8794: 
                   8795:   return (0);
1.164     brouard  8796:  /* endread:*/
1.136     brouard  8797:     printf("Exiting calandcheckages: ");
                   8798:     return (1);
                   8799: }
                   8800: 
1.172     brouard  8801: #if defined(_MSC_VER)
                   8802: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8803: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   8804: //#include "stdafx.h"
                   8805: //#include <stdio.h>
                   8806: //#include <tchar.h>
                   8807: //#include <windows.h>
                   8808: //#include <iostream>
                   8809: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   8810: 
                   8811: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8812: 
                   8813: BOOL IsWow64()
                   8814: {
                   8815:        BOOL bIsWow64 = FALSE;
                   8816: 
                   8817:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   8818:        //  (HANDLE, PBOOL);
                   8819: 
                   8820:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   8821: 
                   8822:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   8823:        const char funcName[] = "IsWow64Process";
                   8824:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   8825:                GetProcAddress(module, funcName);
                   8826: 
                   8827:        if (NULL != fnIsWow64Process)
                   8828:        {
                   8829:                if (!fnIsWow64Process(GetCurrentProcess(),
                   8830:                        &bIsWow64))
                   8831:                        //throw std::exception("Unknown error");
                   8832:                        printf("Unknown error\n");
                   8833:        }
                   8834:        return bIsWow64 != FALSE;
                   8835: }
                   8836: #endif
1.177     brouard  8837: 
1.191     brouard  8838: void syscompilerinfo(int logged)
1.167     brouard  8839:  {
                   8840:    /* #include "syscompilerinfo.h"*/
1.185     brouard  8841:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   8842:    /* /GS /W3 /Gy
                   8843:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   8844:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   8845:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  8846:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   8847:    */ 
                   8848:    /* 64 bits */
1.185     brouard  8849:    /*
                   8850:      /GS /W3 /Gy
                   8851:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   8852:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   8853:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   8854:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   8855:    /* Optimization are useless and O3 is slower than O2 */
                   8856:    /*
                   8857:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   8858:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   8859:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   8860:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   8861:    */
1.186     brouard  8862:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  8863:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   8864:       /PDB:"visual studio
                   8865:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   8866:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   8867:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   8868:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   8869:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   8870:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   8871:       uiAccess='false'"
                   8872:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   8873:       /NOLOGO /TLBID:1
                   8874:    */
1.177     brouard  8875: #if defined __INTEL_COMPILER
1.178     brouard  8876: #if defined(__GNUC__)
                   8877:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   8878: #endif
1.177     brouard  8879: #elif defined(__GNUC__) 
1.179     brouard  8880: #ifndef  __APPLE__
1.174     brouard  8881: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  8882: #endif
1.177     brouard  8883:    struct utsname sysInfo;
1.178     brouard  8884:    int cross = CROSS;
                   8885:    if (cross){
                   8886:           printf("Cross-");
1.191     brouard  8887:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  8888:    }
1.174     brouard  8889: #endif
                   8890: 
1.171     brouard  8891: #include <stdint.h>
1.178     brouard  8892: 
1.191     brouard  8893:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  8894: #if defined(__clang__)
1.191     brouard  8895:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  8896: #endif
                   8897: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  8898:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  8899: #endif
                   8900: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  8901:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  8902: #endif
                   8903: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  8904:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  8905: #endif
                   8906: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  8907:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  8908: #endif
                   8909: #if defined(_MSC_VER)
1.191     brouard  8910:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  8911: #endif
                   8912: #if defined(__PGI)
1.191     brouard  8913:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  8914: #endif
                   8915: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  8916:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  8917: #endif
1.191     brouard  8918:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  8919:    
1.167     brouard  8920: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   8921: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   8922:     // Windows (x64 and x86)
1.191     brouard  8923:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  8924: #elif __unix__ // all unices, not all compilers
                   8925:     // Unix
1.191     brouard  8926:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  8927: #elif __linux__
                   8928:     // linux
1.191     brouard  8929:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  8930: #elif __APPLE__
1.174     brouard  8931:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  8932:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  8933: #endif
                   8934: 
                   8935: /*  __MINGW32__          */
                   8936: /*  __CYGWIN__  */
                   8937: /* __MINGW64__  */
                   8938: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   8939: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   8940: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   8941: /* _WIN64  // Defined for applications for Win64. */
                   8942: /* _M_X64 // Defined for compilations that target x64 processors. */
                   8943: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  8944: 
1.167     brouard  8945: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  8946:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  8947: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  8948:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  8949: #else
1.191     brouard  8950:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  8951: #endif
                   8952: 
1.169     brouard  8953: #if defined(__GNUC__)
                   8954: # if defined(__GNUC_PATCHLEVEL__)
                   8955: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   8956:                             + __GNUC_MINOR__ * 100 \
                   8957:                             + __GNUC_PATCHLEVEL__)
                   8958: # else
                   8959: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   8960:                             + __GNUC_MINOR__ * 100)
                   8961: # endif
1.174     brouard  8962:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  8963:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  8964: 
                   8965:    if (uname(&sysInfo) != -1) {
                   8966:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  8967:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  8968:    }
                   8969:    else
                   8970:       perror("uname() error");
1.179     brouard  8971:    //#ifndef __INTEL_COMPILER 
                   8972: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  8973:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  8974:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  8975: #endif
1.169     brouard  8976: #endif
1.172     brouard  8977: 
                   8978:    //   void main()
                   8979:    //   {
1.169     brouard  8980: #if defined(_MSC_VER)
1.174     brouard  8981:    if (IsWow64()){
1.191     brouard  8982:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   8983:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  8984:    }
                   8985:    else{
1.191     brouard  8986:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   8987:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  8988:    }
1.172     brouard  8989:    //     printf("\nPress Enter to continue...");
                   8990:    //     getchar();
                   8991:    //   }
                   8992: 
1.169     brouard  8993: #endif
                   8994:    
1.167     brouard  8995: 
1.219     brouard  8996: }
1.136     brouard  8997: 
1.219     brouard  8998: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  8999:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9000:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9001:   /* double ftolpl = 1.e-10; */
1.180     brouard  9002:   double age, agebase, agelim;
1.203     brouard  9003:   double tot;
1.180     brouard  9004: 
1.202     brouard  9005:   strcpy(filerespl,"PL_");
                   9006:   strcat(filerespl,fileresu);
                   9007:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9008:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9009:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9010:   }
1.227     brouard  9011:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9012:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9013:   pstamp(ficrespl);
1.203     brouard  9014:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9015:   fprintf(ficrespl,"#Age ");
                   9016:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9017:   fprintf(ficrespl,"\n");
1.180     brouard  9018:   
1.219     brouard  9019:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9020: 
1.219     brouard  9021:   agebase=ageminpar;
                   9022:   agelim=agemaxpar;
1.180     brouard  9023: 
1.227     brouard  9024:   /* i1=pow(2,ncoveff); */
1.234     brouard  9025:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9026:   if (cptcovn < 1){i1=1;}
1.180     brouard  9027: 
1.235     brouard  9028:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.220     brouard  9029:   for(k=1; k<=i1;k++){
1.235     brouard  9030:     if(TKresult[nres]!= k)
                   9031:       continue;
                   9032: 
1.220     brouard  9033:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
1.180     brouard  9034:     /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
1.219     brouard  9035:     //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
1.220     brouard  9036:     /* k=k+1; */
1.219     brouard  9037:     /* to clean */
                   9038:     //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9039:     fprintf(ficrespl,"#******");
                   9040:     printf("#******");
                   9041:     fprintf(ficlog,"#******");
1.227     brouard  9042:     for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9043:       fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
1.219     brouard  9044:       printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9045:       fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9046:     }
1.235     brouard  9047:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9048:       printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9049:       fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9050:     }
1.219     brouard  9051:     fprintf(ficrespl,"******\n");
                   9052:     printf("******\n");
                   9053:     fprintf(ficlog,"******\n");
1.227     brouard  9054:     if(invalidvarcomb[k]){
                   9055:       printf("\nCombination (%d) ignored because no case \n",k); 
                   9056:       fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9057:       fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
1.220     brouard  9058:                                                continue;
1.227     brouard  9059:     }
1.219     brouard  9060: 
                   9061:     fprintf(ficrespl,"#Age ");
1.227     brouard  9062:     for(j=1;j<=cptcoveff;j++) {
1.219     brouard  9063:       fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9064:     }
                   9065:     for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9066:     fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9067:     
1.219     brouard  9068:     for (age=agebase; age<=agelim; age++){
                   9069:       /* for (age=agebase; age<=agebase; age++){ */
1.235     brouard  9070:       prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
1.219     brouard  9071:       fprintf(ficrespl,"%.0f ",age );
1.227     brouard  9072:       for(j=1;j<=cptcoveff;j++)
                   9073:        fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.219     brouard  9074:       tot=0.;
                   9075:       for(i=1; i<=nlstate;i++){
1.227     brouard  9076:        tot +=  prlim[i][i];
                   9077:        fprintf(ficrespl," %.5f", prlim[i][i]);
1.219     brouard  9078:       }
                   9079:       fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9080:     } /* Age */
                   9081:     /* was end of cptcod */
                   9082:   } /* cptcov */
                   9083:   return 0;
1.180     brouard  9084: }
                   9085: 
1.218     brouard  9086: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9087:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9088:        
                   9089:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9090:    * at any age between ageminpar and agemaxpar
                   9091:         */
1.235     brouard  9092:   int i, j, k, i1, nres=0 ;
1.217     brouard  9093:   /* double ftolpl = 1.e-10; */
                   9094:   double age, agebase, agelim;
                   9095:   double tot;
1.218     brouard  9096:   /* double ***mobaverage; */
                   9097:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9098: 
                   9099:   strcpy(fileresplb,"PLB_");
                   9100:   strcat(fileresplb,fileresu);
                   9101:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9102:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9103:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9104:   }
                   9105:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9106:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9107:   pstamp(ficresplb);
                   9108:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9109:   fprintf(ficresplb,"#Age ");
                   9110:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9111:   fprintf(ficresplb,"\n");
                   9112:   
1.218     brouard  9113:   
                   9114:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9115:   
                   9116:   agebase=ageminpar;
                   9117:   agelim=agemaxpar;
                   9118:   
                   9119:   
1.227     brouard  9120:   i1=pow(2,cptcoveff);
1.218     brouard  9121:   if (cptcovn < 1){i1=1;}
1.227     brouard  9122:   
1.235     brouard  9123:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9124:   for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   9125:     if(TKresult[nres]!= k)
                   9126:       continue;
1.218     brouard  9127:     //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9128:     fprintf(ficresplb,"#******");
                   9129:     printf("#******");
                   9130:     fprintf(ficlog,"#******");
1.227     brouard  9131:     for(j=1;j<=cptcoveff ;j++) {/* all covariates */
1.218     brouard  9132:       fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9133:       printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9134:       fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9135:     }
1.235     brouard  9136:     for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9137:       printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9138:       fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9139:       fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9140:     }
1.218     brouard  9141:     fprintf(ficresplb,"******\n");
                   9142:     printf("******\n");
                   9143:     fprintf(ficlog,"******\n");
1.227     brouard  9144:     if(invalidvarcomb[k]){
                   9145:       printf("\nCombination (%d) ignored because no cases \n",k); 
                   9146:       fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9147:       fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9148:       continue;
                   9149:     }
1.218     brouard  9150:     
                   9151:     fprintf(ficresplb,"#Age ");
1.227     brouard  9152:     for(j=1;j<=cptcoveff;j++) {
1.218     brouard  9153:       fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9154:     }
                   9155:     for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9156:     fprintf(ficresplb,"Total Years_to_converge\n");
                   9157:     
                   9158:     
                   9159:     for (age=agebase; age<=agelim; age++){
                   9160:       /* for (age=agebase; age<=agebase; age++){ */
                   9161:       if(mobilavproj > 0){
                   9162:        /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9163:        /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.227     brouard  9164:        bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k);
1.218     brouard  9165:       }else if (mobilavproj == 0){
1.227     brouard  9166:        printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9167:        fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9168:        exit(1);
1.218     brouard  9169:       }else{
1.227     brouard  9170:        /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9171:        bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k);
1.218     brouard  9172:       }
                   9173:       fprintf(ficresplb,"%.0f ",age );
1.227     brouard  9174:       for(j=1;j<=cptcoveff;j++)
                   9175:        fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.218     brouard  9176:       tot=0.;
                   9177:       for(i=1; i<=nlstate;i++){
1.227     brouard  9178:        tot +=  bprlim[i][i];
                   9179:        fprintf(ficresplb," %.5f", bprlim[i][i]);
1.218     brouard  9180:       }
                   9181:       fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9182:     } /* Age */
                   9183:     /* was end of cptcod */
                   9184:   } /* cptcov */
                   9185:   
                   9186:   /* hBijx(p, bage, fage); */
                   9187:   /* fclose(ficrespijb); */
                   9188:   
                   9189:   return 0;
1.217     brouard  9190: }
1.218     brouard  9191:  
1.180     brouard  9192: int hPijx(double *p, int bage, int fage){
                   9193:     /*------------- h Pij x at various ages ------------*/
                   9194: 
                   9195:   int stepsize;
                   9196:   int agelim;
                   9197:   int hstepm;
                   9198:   int nhstepm;
1.235     brouard  9199:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9200: 
                   9201:   double agedeb;
                   9202:   double ***p3mat;
                   9203: 
1.201     brouard  9204:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9205:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9206:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9207:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9208:     }
                   9209:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9210:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9211:   
                   9212:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9213:     /*if (stepm<=24) stepsize=2;*/
                   9214: 
                   9215:     agelim=AGESUP;
                   9216:     hstepm=stepsize*YEARM; /* Every year of age */
                   9217:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9218:                
1.180     brouard  9219:     /* hstepm=1;   aff par mois*/
                   9220:     pstamp(ficrespij);
                   9221:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9222:     i1= pow(2,cptcoveff);
1.218     brouard  9223:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9224:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9225:                /*      k=k+1;  */
1.235     brouard  9226:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9227:     for(k=1; k<=i1;k++){
                   9228:       if(TKresult[nres]!= k)
                   9229:        continue;
1.183     brouard  9230:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9231:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9232:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9233:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9234:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9235:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9236:       }
1.183     brouard  9237:       fprintf(ficrespij,"******\n");
                   9238:       
                   9239:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9240:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9241:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9242:        
                   9243:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9244:        
1.183     brouard  9245:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9246:        oldm=oldms;savm=savms;
1.235     brouard  9247:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9248:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9249:        for(i=1; i<=nlstate;i++)
                   9250:          for(j=1; j<=nlstate+ndeath;j++)
                   9251:            fprintf(ficrespij," %1d-%1d",i,j);
                   9252:        fprintf(ficrespij,"\n");
                   9253:        for (h=0; h<=nhstepm; h++){
                   9254:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9255:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9256:          for(i=1; i<=nlstate;i++)
                   9257:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9258:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9259:          fprintf(ficrespij,"\n");
                   9260:        }
1.183     brouard  9261:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9262:        fprintf(ficrespij,"\n");
                   9263:       }
1.180     brouard  9264:       /*}*/
                   9265:     }
1.218     brouard  9266:     return 0;
1.180     brouard  9267: }
1.218     brouard  9268:  
                   9269:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9270:     /*------------- h Bij x at various ages ------------*/
                   9271: 
                   9272:   int stepsize;
1.218     brouard  9273:   /* int agelim; */
                   9274:        int ageminl;
1.217     brouard  9275:   int hstepm;
                   9276:   int nhstepm;
                   9277:   int h, i, i1, j, k;
1.218     brouard  9278:        
1.217     brouard  9279:   double agedeb;
                   9280:   double ***p3mat;
1.218     brouard  9281:        
                   9282:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9283:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9284:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9285:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9286:   }
                   9287:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9288:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9289:   
                   9290:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9291:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9292:   
1.218     brouard  9293:   /* agelim=AGESUP; */
                   9294:   ageminl=30;
                   9295:   hstepm=stepsize*YEARM; /* Every year of age */
                   9296:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9297:   
                   9298:   /* hstepm=1;   aff par mois*/
                   9299:   pstamp(ficrespijb);
                   9300:   fprintf(ficrespijb,"#****** h Pij x Back Probability to be in state i at age x-h being in j at x ");
1.227     brouard  9301:   i1= pow(2,cptcoveff);
1.218     brouard  9302:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9303:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9304:   /*   k=k+1;  */
1.227     brouard  9305:   for (k=1; k <= (int) pow(2,cptcoveff); k++){
1.218     brouard  9306:     fprintf(ficrespijb,"\n#****** ");
1.227     brouard  9307:     for(j=1;j<=cptcoveff;j++)
1.218     brouard  9308:       fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9309:     fprintf(ficrespijb,"******\n");
1.222     brouard  9310:     if(invalidvarcomb[k]){
                   9311:       fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9312:       continue;
                   9313:     }
1.218     brouard  9314:     
                   9315:     /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9316:     for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9317:       /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9318:       nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9319:       nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9320:       
                   9321:       /*         nhstepm=nhstepm*YEARM; aff par mois*/
                   9322:       
                   9323:       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9324:       /* oldm=oldms;savm=savms; */
                   9325:       /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9326:       hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9327:       /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
                   9328:       fprintf(ficrespijb,"# Cov Agex agex-h hpijx with i,j=");
                   9329:       for(i=1; i<=nlstate;i++)
                   9330:        for(j=1; j<=nlstate+ndeath;j++)
                   9331:          fprintf(ficrespijb," %1d-%1d",i,j);
                   9332:       fprintf(ficrespijb,"\n");
                   9333:       for (h=0; h<=nhstepm; h++){
                   9334:        /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9335:        fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9336:        /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
1.217     brouard  9337:        for(i=1; i<=nlstate;i++)
                   9338:          for(j=1; j<=nlstate+ndeath;j++)
1.218     brouard  9339:            fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
1.217     brouard  9340:        fprintf(ficrespijb,"\n");
                   9341:       }
1.218     brouard  9342:       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9343:       fprintf(ficrespijb,"\n");
1.217     brouard  9344:     }
1.218     brouard  9345:     /*}*/
                   9346:   }
                   9347:   return 0;
                   9348:  } /*  hBijx */
1.217     brouard  9349: 
1.180     brouard  9350: 
1.136     brouard  9351: /***********************************************/
                   9352: /**************** Main Program *****************/
                   9353: /***********************************************/
                   9354: 
                   9355: int main(int argc, char *argv[])
                   9356: {
                   9357: #ifdef GSL
                   9358:   const gsl_multimin_fminimizer_type *T;
                   9359:   size_t iteri = 0, it;
                   9360:   int rval = GSL_CONTINUE;
                   9361:   int status = GSL_SUCCESS;
                   9362:   double ssval;
                   9363: #endif
                   9364:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9365:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9366:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9367:   int jj, ll, li, lj, lk;
1.136     brouard  9368:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9369:   int num_filled;
1.136     brouard  9370:   int itimes;
                   9371:   int NDIM=2;
                   9372:   int vpopbased=0;
1.235     brouard  9373:   int nres=0;
1.136     brouard  9374: 
1.164     brouard  9375:   char ca[32], cb[32];
1.136     brouard  9376:   /*  FILE *fichtm; *//* Html File */
                   9377:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9378:   struct stat info;
1.191     brouard  9379:   double agedeb=0.;
1.194     brouard  9380: 
                   9381:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9382:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9383: 
1.165     brouard  9384:   double fret;
1.191     brouard  9385:   double dum=0.; /* Dummy variable */
1.136     brouard  9386:   double ***p3mat;
1.218     brouard  9387:   /* double ***mobaverage; */
1.164     brouard  9388: 
                   9389:   char line[MAXLINE];
1.197     brouard  9390:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9391: 
1.234     brouard  9392:   char  modeltemp[MAXLINE];
1.230     brouard  9393:   char resultline[MAXLINE];
                   9394:   
1.136     brouard  9395:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9396:   char *tok, *val; /* pathtot */
1.136     brouard  9397:   int firstobs=1, lastobs=10;
1.195     brouard  9398:   int c,  h , cpt, c2;
1.191     brouard  9399:   int jl=0;
                   9400:   int i1, j1, jk, stepsize=0;
1.194     brouard  9401:   int count=0;
                   9402: 
1.164     brouard  9403:   int *tab; 
1.136     brouard  9404:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9405:   int backcast=0;
1.136     brouard  9406:   int mobilav=0,popforecast=0;
1.191     brouard  9407:   int hstepm=0, nhstepm=0;
1.136     brouard  9408:   int agemortsup;
                   9409:   float  sumlpop=0.;
                   9410:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9411:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9412: 
1.191     brouard  9413:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9414:   double ftolpl=FTOL;
                   9415:   double **prlim;
1.217     brouard  9416:   double **bprlim;
1.136     brouard  9417:   double ***param; /* Matrix of parameters */
                   9418:   double  *p;
                   9419:   double **matcov; /* Matrix of covariance */
1.203     brouard  9420:   double **hess; /* Hessian matrix */
1.136     brouard  9421:   double ***delti3; /* Scale */
                   9422:   double *delti; /* Scale */
                   9423:   double ***eij, ***vareij;
                   9424:   double **varpl; /* Variances of prevalence limits by age */
                   9425:   double *epj, vepp;
1.164     brouard  9426: 
1.136     brouard  9427:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9428:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9429: 
1.136     brouard  9430:   double **ximort;
1.145     brouard  9431:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9432:   int *dcwave;
                   9433: 
1.164     brouard  9434:   char z[1]="c";
1.136     brouard  9435: 
                   9436:   /*char  *strt;*/
                   9437:   char strtend[80];
1.126     brouard  9438: 
1.164     brouard  9439: 
1.126     brouard  9440: /*   setlocale (LC_ALL, ""); */
                   9441: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9442: /*   textdomain (PACKAGE); */
                   9443: /*   setlocale (LC_CTYPE, ""); */
                   9444: /*   setlocale (LC_MESSAGES, ""); */
                   9445: 
                   9446:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9447:   rstart_time = time(NULL);  
                   9448:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9449:   start_time = *localtime(&rstart_time);
1.126     brouard  9450:   curr_time=start_time;
1.157     brouard  9451:   /*tml = *localtime(&start_time.tm_sec);*/
                   9452:   /* strcpy(strstart,asctime(&tml)); */
                   9453:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9454: 
                   9455: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9456: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9457: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9458: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9459: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9460: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9461: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9462: /*   strt=asctime(&tmg); */
                   9463: /*   printf("Time(after) =%s",strstart);  */
                   9464: /*  (void) time (&time_value);
                   9465: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9466: *  tm = *localtime(&time_value);
                   9467: *  strstart=asctime(&tm);
                   9468: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9469: */
                   9470: 
                   9471:   nberr=0; /* Number of errors and warnings */
                   9472:   nbwarn=0;
1.184     brouard  9473: #ifdef WIN32
                   9474:   _getcwd(pathcd, size);
                   9475: #else
1.126     brouard  9476:   getcwd(pathcd, size);
1.184     brouard  9477: #endif
1.191     brouard  9478:   syscompilerinfo(0);
1.196     brouard  9479:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9480:   if(argc <=1){
                   9481:     printf("\nEnter the parameter file name: ");
1.205     brouard  9482:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9483:       printf("ERROR Empty parameter file name\n");
                   9484:       goto end;
                   9485:     }
1.126     brouard  9486:     i=strlen(pathr);
                   9487:     if(pathr[i-1]=='\n')
                   9488:       pathr[i-1]='\0';
1.156     brouard  9489:     i=strlen(pathr);
1.205     brouard  9490:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9491:       pathr[i-1]='\0';
1.205     brouard  9492:     }
                   9493:     i=strlen(pathr);
                   9494:     if( i==0 ){
                   9495:       printf("ERROR Empty parameter file name\n");
                   9496:       goto end;
                   9497:     }
                   9498:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9499:       printf("Pathr |%s|\n",pathr);
                   9500:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9501:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9502:       strcpy (pathtot, val);
                   9503:       if(pathr[0] == '\0') break; /* Dirty */
                   9504:     }
                   9505:   }
                   9506:   else{
                   9507:     strcpy(pathtot,argv[1]);
                   9508:   }
                   9509:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9510:   /*cygwin_split_path(pathtot,path,optionfile);
                   9511:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9512:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9513: 
                   9514:   /* Split argv[0], imach program to get pathimach */
                   9515:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9516:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9517:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9518:  /*   strcpy(pathimach,argv[0]); */
                   9519:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9520:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9521:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9522: #ifdef WIN32
                   9523:   _chdir(path); /* Can be a relative path */
                   9524:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9525: #else
1.126     brouard  9526:   chdir(path); /* Can be a relative path */
1.184     brouard  9527:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9528: #endif
                   9529:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9530:   strcpy(command,"mkdir ");
                   9531:   strcat(command,optionfilefiname);
                   9532:   if((outcmd=system(command)) != 0){
1.169     brouard  9533:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9534:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9535:     /* fclose(ficlog); */
                   9536: /*     exit(1); */
                   9537:   }
                   9538: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9539: /*     perror("mkdir"); */
                   9540: /*   } */
                   9541: 
                   9542:   /*-------- arguments in the command line --------*/
                   9543: 
1.186     brouard  9544:   /* Main Log file */
1.126     brouard  9545:   strcat(filelog, optionfilefiname);
                   9546:   strcat(filelog,".log");    /* */
                   9547:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9548:     printf("Problem with logfile %s\n",filelog);
                   9549:     goto end;
                   9550:   }
                   9551:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9552:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9553:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9554:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9555:  path=%s \n\
                   9556:  optionfile=%s\n\
                   9557:  optionfilext=%s\n\
1.156     brouard  9558:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9559: 
1.197     brouard  9560:   syscompilerinfo(1);
1.167     brouard  9561: 
1.126     brouard  9562:   printf("Local time (at start):%s",strstart);
                   9563:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9564:   fflush(ficlog);
                   9565: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9566: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9567: 
                   9568:   /* */
                   9569:   strcpy(fileres,"r");
                   9570:   strcat(fileres, optionfilefiname);
1.201     brouard  9571:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9572:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9573:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9574: 
1.186     brouard  9575:   /* Main ---------arguments file --------*/
1.126     brouard  9576: 
                   9577:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9578:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9579:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9580:     fflush(ficlog);
1.149     brouard  9581:     /* goto end; */
                   9582:     exit(70); 
1.126     brouard  9583:   }
                   9584: 
                   9585: 
                   9586: 
                   9587:   strcpy(filereso,"o");
1.201     brouard  9588:   strcat(filereso,fileresu);
1.126     brouard  9589:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9590:     printf("Problem with Output resultfile: %s\n", filereso);
                   9591:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   9592:     fflush(ficlog);
                   9593:     goto end;
                   9594:   }
                   9595: 
                   9596:   /* Reads comments: lines beginning with '#' */
                   9597:   numlinepar=0;
1.197     brouard  9598: 
                   9599:     /* First parameter line */
                   9600:   while(fgets(line, MAXLINE, ficpar)) {
                   9601:     /* If line starts with a # it is a comment */
                   9602:     if (line[0] == '#') {
                   9603:       numlinepar++;
                   9604:       fputs(line,stdout);
                   9605:       fputs(line,ficparo);
                   9606:       fputs(line,ficlog);
                   9607:       continue;
                   9608:     }else
                   9609:       break;
                   9610:   }
                   9611:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   9612:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   9613:     if (num_filled != 5) {
                   9614:       printf("Should be 5 parameters\n");
                   9615:     }
1.126     brouard  9616:     numlinepar++;
1.197     brouard  9617:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   9618:   }
                   9619:   /* Second parameter line */
                   9620:   while(fgets(line, MAXLINE, ficpar)) {
                   9621:     /* If line starts with a # it is a comment */
                   9622:     if (line[0] == '#') {
                   9623:       numlinepar++;
                   9624:       fputs(line,stdout);
                   9625:       fputs(line,ficparo);
                   9626:       fputs(line,ficlog);
                   9627:       continue;
                   9628:     }else
                   9629:       break;
                   9630:   }
1.223     brouard  9631:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   9632:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   9633:     if (num_filled != 11) {
                   9634:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  9635:       printf("but line=%s\n",line);
1.197     brouard  9636:     }
1.223     brouard  9637:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  9638:   }
1.203     brouard  9639:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  9640:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  9641:   /* Third parameter line */
                   9642:   while(fgets(line, MAXLINE, ficpar)) {
                   9643:     /* If line starts with a # it is a comment */
                   9644:     if (line[0] == '#') {
                   9645:       numlinepar++;
                   9646:       fputs(line,stdout);
                   9647:       fputs(line,ficparo);
                   9648:       fputs(line,ficlog);
                   9649:       continue;
                   9650:     }else
                   9651:       break;
                   9652:   }
1.201     brouard  9653:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   9654:     if (num_filled == 0)
                   9655:             model[0]='\0';
                   9656:     else if (num_filled != 1){
1.197     brouard  9657:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9658:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   9659:       model[0]='\0';
                   9660:       goto end;
                   9661:     }
                   9662:     else{
                   9663:       if (model[0]=='+'){
                   9664:        for(i=1; i<=strlen(model);i++)
                   9665:          modeltemp[i-1]=model[i];
1.201     brouard  9666:        strcpy(model,modeltemp); 
1.197     brouard  9667:       }
                   9668:     }
1.199     brouard  9669:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  9670:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  9671:   }
                   9672:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   9673:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   9674:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  9675:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   9676:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  9677:   fflush(ficlog);
1.190     brouard  9678:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   9679:   if(model[0]=='#'){
1.187     brouard  9680:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   9681:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   9682:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   9683:     if(mle != -1){
                   9684:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   9685:       exit(1);
                   9686:     }
                   9687:   }
1.126     brouard  9688:   while((c=getc(ficpar))=='#' && c!= EOF){
                   9689:     ungetc(c,ficpar);
                   9690:     fgets(line, MAXLINE, ficpar);
                   9691:     numlinepar++;
1.195     brouard  9692:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   9693:       z[0]=line[1];
                   9694:     }
                   9695:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  9696:     fputs(line, stdout);
                   9697:     //puts(line);
1.126     brouard  9698:     fputs(line,ficparo);
                   9699:     fputs(line,ficlog);
                   9700:   }
                   9701:   ungetc(c,ficpar);
                   9702: 
                   9703:    
1.145     brouard  9704:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  9705:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  9706:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  9707:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  9708:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   9709:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   9710:      v1+v2*age+v2*v3 makes cptcovn = 3
                   9711:   */
                   9712:   if (strlen(model)>1) 
1.187     brouard  9713:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  9714:   else
1.187     brouard  9715:     ncovmodel=2; /* Constant and age */
1.133     brouard  9716:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   9717:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  9718:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   9719:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9720:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   9721:     fflush(stdout);
                   9722:     fclose (ficlog);
                   9723:     goto end;
                   9724:   }
1.126     brouard  9725:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9726:   delti=delti3[1][1];
                   9727:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   9728:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
                   9729:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  9730:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   9731:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9732:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   9733:     fclose (ficparo);
                   9734:     fclose (ficlog);
                   9735:     goto end;
                   9736:     exit(0);
1.220     brouard  9737:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  9738:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  9739:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   9740:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  9741:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9742:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9743:     hess=matrix(1,npar,1,npar);
1.220     brouard  9744:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  9745:     /* Read guessed parameters */
1.126     brouard  9746:     /* Reads comments: lines beginning with '#' */
                   9747:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9748:       ungetc(c,ficpar);
                   9749:       fgets(line, MAXLINE, ficpar);
                   9750:       numlinepar++;
1.141     brouard  9751:       fputs(line,stdout);
1.126     brouard  9752:       fputs(line,ficparo);
                   9753:       fputs(line,ficlog);
                   9754:     }
                   9755:     ungetc(c,ficpar);
                   9756:     
                   9757:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   9758:     for(i=1; i <=nlstate; i++){
1.234     brouard  9759:       j=0;
1.126     brouard  9760:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  9761:        if(jj==i) continue;
                   9762:        j++;
                   9763:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9764:        if ((i1 != i) || (j1 != jj)){
                   9765:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  9766: It might be a problem of design; if ncovcol and the model are correct\n \
                   9767: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  9768:          exit(1);
                   9769:        }
                   9770:        fprintf(ficparo,"%1d%1d",i1,j1);
                   9771:        if(mle==1)
                   9772:          printf("%1d%1d",i,jj);
                   9773:        fprintf(ficlog,"%1d%1d",i,jj);
                   9774:        for(k=1; k<=ncovmodel;k++){
                   9775:          fscanf(ficpar," %lf",&param[i][j][k]);
                   9776:          if(mle==1){
                   9777:            printf(" %lf",param[i][j][k]);
                   9778:            fprintf(ficlog," %lf",param[i][j][k]);
                   9779:          }
                   9780:          else
                   9781:            fprintf(ficlog," %lf",param[i][j][k]);
                   9782:          fprintf(ficparo," %lf",param[i][j][k]);
                   9783:        }
                   9784:        fscanf(ficpar,"\n");
                   9785:        numlinepar++;
                   9786:        if(mle==1)
                   9787:          printf("\n");
                   9788:        fprintf(ficlog,"\n");
                   9789:        fprintf(ficparo,"\n");
1.126     brouard  9790:       }
                   9791:     }  
                   9792:     fflush(ficlog);
1.234     brouard  9793:     
1.145     brouard  9794:     /* Reads scales values */
1.126     brouard  9795:     p=param[1][1];
                   9796:     
                   9797:     /* Reads comments: lines beginning with '#' */
                   9798:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9799:       ungetc(c,ficpar);
                   9800:       fgets(line, MAXLINE, ficpar);
                   9801:       numlinepar++;
1.141     brouard  9802:       fputs(line,stdout);
1.126     brouard  9803:       fputs(line,ficparo);
                   9804:       fputs(line,ficlog);
                   9805:     }
                   9806:     ungetc(c,ficpar);
                   9807: 
                   9808:     for(i=1; i <=nlstate; i++){
                   9809:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  9810:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   9811:        if ( (i1-i) * (j1-j) != 0){
                   9812:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   9813:          exit(1);
                   9814:        }
                   9815:        printf("%1d%1d",i,j);
                   9816:        fprintf(ficparo,"%1d%1d",i1,j1);
                   9817:        fprintf(ficlog,"%1d%1d",i1,j1);
                   9818:        for(k=1; k<=ncovmodel;k++){
                   9819:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   9820:          printf(" %le",delti3[i][j][k]);
                   9821:          fprintf(ficparo," %le",delti3[i][j][k]);
                   9822:          fprintf(ficlog," %le",delti3[i][j][k]);
                   9823:        }
                   9824:        fscanf(ficpar,"\n");
                   9825:        numlinepar++;
                   9826:        printf("\n");
                   9827:        fprintf(ficparo,"\n");
                   9828:        fprintf(ficlog,"\n");
1.126     brouard  9829:       }
                   9830:     }
                   9831:     fflush(ficlog);
1.234     brouard  9832:     
1.145     brouard  9833:     /* Reads covariance matrix */
1.126     brouard  9834:     delti=delti3[1][1];
1.220     brouard  9835:                
                   9836:                
1.126     brouard  9837:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  9838:                
1.126     brouard  9839:     /* Reads comments: lines beginning with '#' */
                   9840:     while((c=getc(ficpar))=='#' && c!= EOF){
                   9841:       ungetc(c,ficpar);
                   9842:       fgets(line, MAXLINE, ficpar);
                   9843:       numlinepar++;
1.141     brouard  9844:       fputs(line,stdout);
1.126     brouard  9845:       fputs(line,ficparo);
                   9846:       fputs(line,ficlog);
                   9847:     }
                   9848:     ungetc(c,ficpar);
1.220     brouard  9849:                
1.126     brouard  9850:     matcov=matrix(1,npar,1,npar);
1.203     brouard  9851:     hess=matrix(1,npar,1,npar);
1.131     brouard  9852:     for(i=1; i <=npar; i++)
                   9853:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  9854:                
1.194     brouard  9855:     /* Scans npar lines */
1.126     brouard  9856:     for(i=1; i <=npar; i++){
1.226     brouard  9857:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  9858:       if(count != 3){
1.226     brouard  9859:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  9860: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   9861: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  9862:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  9863: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   9864: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  9865:        exit(1);
1.220     brouard  9866:       }else{
1.226     brouard  9867:        if(mle==1)
                   9868:          printf("%1d%1d%d",i1,j1,jk);
                   9869:       }
                   9870:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   9871:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  9872:       for(j=1; j <=i; j++){
1.226     brouard  9873:        fscanf(ficpar," %le",&matcov[i][j]);
                   9874:        if(mle==1){
                   9875:          printf(" %.5le",matcov[i][j]);
                   9876:        }
                   9877:        fprintf(ficlog," %.5le",matcov[i][j]);
                   9878:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  9879:       }
                   9880:       fscanf(ficpar,"\n");
                   9881:       numlinepar++;
                   9882:       if(mle==1)
1.220     brouard  9883:                                printf("\n");
1.126     brouard  9884:       fprintf(ficlog,"\n");
                   9885:       fprintf(ficparo,"\n");
                   9886:     }
1.194     brouard  9887:     /* End of read covariance matrix npar lines */
1.126     brouard  9888:     for(i=1; i <=npar; i++)
                   9889:       for(j=i+1;j<=npar;j++)
1.226     brouard  9890:        matcov[i][j]=matcov[j][i];
1.126     brouard  9891:     
                   9892:     if(mle==1)
                   9893:       printf("\n");
                   9894:     fprintf(ficlog,"\n");
                   9895:     
                   9896:     fflush(ficlog);
                   9897:     
                   9898:     /*-------- Rewriting parameter file ----------*/
                   9899:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   9900:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   9901:     strcat(rfileres,".");    /* */
                   9902:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   9903:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  9904:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   9905:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  9906:     }
                   9907:     fprintf(ficres,"#%s\n",version);
                   9908:   }    /* End of mle != -3 */
1.218     brouard  9909:   
1.186     brouard  9910:   /*  Main data
                   9911:    */
1.126     brouard  9912:   n= lastobs;
                   9913:   num=lvector(1,n);
                   9914:   moisnais=vector(1,n);
                   9915:   annais=vector(1,n);
                   9916:   moisdc=vector(1,n);
                   9917:   andc=vector(1,n);
1.220     brouard  9918:   weight=vector(1,n);
1.126     brouard  9919:   agedc=vector(1,n);
                   9920:   cod=ivector(1,n);
1.220     brouard  9921:   for(i=1;i<=n;i++){
1.234     brouard  9922:     num[i]=0;
                   9923:     moisnais[i]=0;
                   9924:     annais[i]=0;
                   9925:     moisdc[i]=0;
                   9926:     andc[i]=0;
                   9927:     agedc[i]=0;
                   9928:     cod[i]=0;
                   9929:     weight[i]=1.0; /* Equal weights, 1 by default */
                   9930:   }
1.126     brouard  9931:   mint=matrix(1,maxwav,1,n);
                   9932:   anint=matrix(1,maxwav,1,n);
1.131     brouard  9933:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  9934:   tab=ivector(1,NCOVMAX);
1.144     brouard  9935:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  9936:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  9937: 
1.136     brouard  9938:   /* Reads data from file datafile */
                   9939:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   9940:     goto end;
                   9941: 
                   9942:   /* Calculation of the number of parameters from char model */
1.234     brouard  9943:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  9944:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   9945:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   9946:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   9947:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  9948:   */
                   9949:   
                   9950:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   9951:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   9952:   TvarsD=ivector(1,NCOVMAX); /*  */
                   9953:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   9954:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  9955:   TvarF=ivector(1,NCOVMAX); /*  */
                   9956:   TvarFind=ivector(1,NCOVMAX); /*  */
                   9957:   TvarV=ivector(1,NCOVMAX); /*  */
                   9958:   TvarVind=ivector(1,NCOVMAX); /*  */
                   9959:   TvarA=ivector(1,NCOVMAX); /*  */
                   9960:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  9961:   TvarFD=ivector(1,NCOVMAX); /*  */
                   9962:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   9963:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   9964:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   9965:   TvarVD=ivector(1,NCOVMAX); /*  */
                   9966:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   9967:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   9968:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   9969: 
1.230     brouard  9970:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  9971:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  9972:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   9973:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   9974:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  9975:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   9976:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   9977:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   9978:   */
                   9979:   /* For model-covariate k tells which data-covariate to use but
                   9980:     because this model-covariate is a construction we invent a new column
                   9981:     ncovcol + k1
                   9982:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   9983:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  9984:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   9985:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  9986:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   9987:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  9988:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  9989:   */
1.145     brouard  9990:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   9991:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  9992:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   9993:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  9994:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  9995:                         4 covariates (3 plus signs)
                   9996:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   9997:                      */  
1.230     brouard  9998:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  9999:                                * individual dummy, fixed or varying:
                   10000:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10001:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10002:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10003:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10004:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10005:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10006:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10007:                                * individual quantitative, fixed or varying:
                   10008:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10009:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10010:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10011: /* Main decodemodel */
                   10012: 
1.187     brouard  10013: 
1.223     brouard  10014:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10015:     goto end;
                   10016: 
1.137     brouard  10017:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10018:     nbwarn++;
                   10019:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10020:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10021:   }
1.136     brouard  10022:     /*  if(mle==1){*/
1.137     brouard  10023:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10024:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10025:   }
                   10026: 
                   10027:     /*-calculation of age at interview from date of interview and age at death -*/
                   10028:   agev=matrix(1,maxwav,1,imx);
                   10029: 
                   10030:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10031:     goto end;
                   10032: 
1.126     brouard  10033: 
1.136     brouard  10034:   agegomp=(int)agemin;
                   10035:   free_vector(moisnais,1,n);
                   10036:   free_vector(annais,1,n);
1.126     brouard  10037:   /* free_matrix(mint,1,maxwav,1,n);
                   10038:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10039:   /* free_vector(moisdc,1,n); */
                   10040:   /* free_vector(andc,1,n); */
1.145     brouard  10041:   /* */
                   10042:   
1.126     brouard  10043:   wav=ivector(1,imx);
1.214     brouard  10044:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10045:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10046:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10047:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10048:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10049:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10050:    
                   10051:   /* Concatenates waves */
1.214     brouard  10052:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10053:      Death is a valid wave (if date is known).
                   10054:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10055:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10056:      and mw[mi+1][i]. dh depends on stepm.
                   10057:   */
                   10058: 
1.126     brouard  10059:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.145     brouard  10060:   /* */
                   10061:  
1.215     brouard  10062:   free_vector(moisdc,1,n);
                   10063:   free_vector(andc,1,n);
                   10064: 
1.126     brouard  10065:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10066:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10067:   ncodemax[1]=1;
1.145     brouard  10068:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10069:   cptcoveff=0;
1.220     brouard  10070:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10071:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10072:   }
                   10073:   
                   10074:   ncovcombmax=pow(2,cptcoveff);
                   10075:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10076:   for(i=1;i<ncovcombmax;i++)
                   10077:     invalidvarcomb[i]=0;
                   10078:   
1.211     brouard  10079:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10080:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10081:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10082:   
1.200     brouard  10083:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10084:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10085:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10086:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10087:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10088:    * (currently 0 or 1) in the data.
                   10089:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10090:    * corresponding modality (h,j).
                   10091:    */
                   10092: 
1.145     brouard  10093:   h=0;
                   10094:   /*if (cptcovn > 0) */
1.126     brouard  10095:   m=pow(2,cptcoveff);
                   10096:  
1.144     brouard  10097:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10098:           * For k=4 covariates, h goes from 1 to m=2**k
                   10099:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10100:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10101:           *     h\k   1     2     3     4
1.143     brouard  10102:           *______________________________  
                   10103:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10104:           *     2     2     1     1     1
                   10105:           *     3 i=2 1     2     1     1
                   10106:           *     4     2     2     1     1
                   10107:           *     5 i=3 1 i=2 1     2     1
                   10108:           *     6     2     1     2     1
                   10109:           *     7 i=4 1     2     2     1
                   10110:           *     8     2     2     2     1
1.197     brouard  10111:           *     9 i=5 1 i=3 1 i=2 1     2
                   10112:           *    10     2     1     1     2
                   10113:           *    11 i=6 1     2     1     2
                   10114:           *    12     2     2     1     2
                   10115:           *    13 i=7 1 i=4 1     2     2    
                   10116:           *    14     2     1     2     2
                   10117:           *    15 i=8 1     2     2     2
                   10118:           *    16     2     2     2     2
1.143     brouard  10119:           */
1.212     brouard  10120:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10121:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10122:      * and the value of each covariate?
                   10123:      * V1=1, V2=1, V3=2, V4=1 ?
                   10124:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10125:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10126:      * In order to get the real value in the data, we use nbcode
                   10127:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10128:      * We are keeping this crazy system in order to be able (in the future?) 
                   10129:      * to have more than 2 values (0 or 1) for a covariate.
                   10130:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10131:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10132:      *              bbbbbbbb
                   10133:      *              76543210     
                   10134:      *   h-1        00000101 (6-1=5)
1.219     brouard  10135:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10136:      *           &
                   10137:      *     1        00000001 (1)
1.219     brouard  10138:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10139:      *          +1= 00000001 =1 
1.211     brouard  10140:      *
                   10141:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10142:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10143:      *    >>k'            11
                   10144:      *          &   00000001
                   10145:      *            = 00000001
                   10146:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10147:      * Reverse h=6 and m=16?
                   10148:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10149:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10150:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10151:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10152:      * V3=decodtabm(14,3,2**4)=2
                   10153:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10154:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10155:      *          &1 000000001
                   10156:      *           = 000000001
                   10157:      *         +1= 000000010 =2
                   10158:      *                  2211
                   10159:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10160:      *                  V3=2
1.220     brouard  10161:                 * codtabm and decodtabm are identical
1.211     brouard  10162:      */
                   10163: 
1.145     brouard  10164: 
                   10165:  free_ivector(Ndum,-1,NCOVMAX);
                   10166: 
                   10167: 
1.126     brouard  10168:     
1.186     brouard  10169:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10170:   strcpy(optionfilegnuplot,optionfilefiname);
                   10171:   if(mle==-3)
1.201     brouard  10172:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10173:   strcat(optionfilegnuplot,".gp");
                   10174: 
                   10175:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10176:     printf("Problem with file %s",optionfilegnuplot);
                   10177:   }
                   10178:   else{
1.204     brouard  10179:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10180:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10181:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10182:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10183:   }
                   10184:   /*  fclose(ficgp);*/
1.186     brouard  10185: 
                   10186: 
                   10187:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10188: 
                   10189:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10190:   if(mle==-3)
1.201     brouard  10191:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10192:   strcat(optionfilehtm,".htm");
                   10193:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10194:     printf("Problem with %s \n",optionfilehtm);
                   10195:     exit(0);
1.126     brouard  10196:   }
                   10197: 
                   10198:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10199:   strcat(optionfilehtmcov,"-cov.htm");
                   10200:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10201:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10202:   }
                   10203:   else{
                   10204:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10205: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10206: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10207:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10208:   }
                   10209: 
1.213     brouard  10210:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10211: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10212: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10213: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10214: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10215: \n\
                   10216: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10217:  <ul><li><h4>Parameter files</h4>\n\
                   10218:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10219:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10220:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10221:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10222:  - Date and time at start: %s</ul>\n",\
                   10223:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10224:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10225:          fileres,fileres,\
                   10226:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10227:   fflush(fichtm);
                   10228: 
                   10229:   strcpy(pathr,path);
                   10230:   strcat(pathr,optionfilefiname);
1.184     brouard  10231: #ifdef WIN32
                   10232:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10233: #else
1.126     brouard  10234:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10235: #endif
                   10236:          
1.126     brouard  10237:   
1.220     brouard  10238:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10239:                 and for any valid combination of covariates
1.126     brouard  10240:      and prints on file fileres'p'. */
1.227     brouard  10241:   freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
                   10242:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10243: 
                   10244:   fprintf(fichtm,"\n");
                   10245:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10246: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10247: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10248:          imx,agemin,agemax,jmin,jmax,jmean);
                   10249:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10250:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10251:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10252:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10253:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10254: 
1.126     brouard  10255:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10256:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10257:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10258: 
                   10259:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10260:   /* For mortality only */
1.126     brouard  10261:   if (mle==-3){
1.136     brouard  10262:     ximort=matrix(1,NDIM,1,NDIM); 
1.220     brouard  10263:                for(i=1;i<=NDIM;i++)
                   10264:                        for(j=1;j<=NDIM;j++)
                   10265:                                ximort[i][j]=0.;
1.186     brouard  10266:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10267:     cens=ivector(1,n);
                   10268:     ageexmed=vector(1,n);
                   10269:     agecens=vector(1,n);
                   10270:     dcwave=ivector(1,n);
1.223     brouard  10271:                
1.126     brouard  10272:     for (i=1; i<=imx; i++){
                   10273:       dcwave[i]=-1;
                   10274:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10275:        if (s[m][i]>nlstate) {
                   10276:          dcwave[i]=m;
                   10277:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10278:          break;
                   10279:        }
1.126     brouard  10280:     }
1.226     brouard  10281:     
1.126     brouard  10282:     for (i=1; i<=imx; i++) {
                   10283:       if (wav[i]>0){
1.226     brouard  10284:        ageexmed[i]=agev[mw[1][i]][i];
                   10285:        j=wav[i];
                   10286:        agecens[i]=1.; 
                   10287:        
                   10288:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10289:          agecens[i]=agev[mw[j][i]][i];
                   10290:          cens[i]= 1;
                   10291:        }else if (ageexmed[i]< 1) 
                   10292:          cens[i]= -1;
                   10293:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10294:          cens[i]=0 ;
1.126     brouard  10295:       }
                   10296:       else cens[i]=-1;
                   10297:     }
                   10298:     
                   10299:     for (i=1;i<=NDIM;i++) {
                   10300:       for (j=1;j<=NDIM;j++)
1.226     brouard  10301:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10302:     }
                   10303:     
1.145     brouard  10304:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10305:     /*printf("%lf %lf", p[1], p[2]);*/
                   10306:     
                   10307:     
1.136     brouard  10308: #ifdef GSL
                   10309:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10310: #else
1.126     brouard  10311:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10312: #endif
1.201     brouard  10313:     strcpy(filerespow,"POW-MORT_"); 
                   10314:     strcat(filerespow,fileresu);
1.126     brouard  10315:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10316:       printf("Problem with resultfile: %s\n", filerespow);
                   10317:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10318:     }
1.136     brouard  10319: #ifdef GSL
                   10320:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10321: #else
1.126     brouard  10322:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10323: #endif
1.126     brouard  10324:     /*  for (i=1;i<=nlstate;i++)
                   10325:        for(j=1;j<=nlstate+ndeath;j++)
                   10326:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10327:     */
                   10328:     fprintf(ficrespow,"\n");
1.136     brouard  10329: #ifdef GSL
                   10330:     /* gsl starts here */ 
                   10331:     T = gsl_multimin_fminimizer_nmsimplex;
                   10332:     gsl_multimin_fminimizer *sfm = NULL;
                   10333:     gsl_vector *ss, *x;
                   10334:     gsl_multimin_function minex_func;
                   10335: 
                   10336:     /* Initial vertex size vector */
                   10337:     ss = gsl_vector_alloc (NDIM);
                   10338:     
                   10339:     if (ss == NULL){
                   10340:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10341:     }
                   10342:     /* Set all step sizes to 1 */
                   10343:     gsl_vector_set_all (ss, 0.001);
                   10344: 
                   10345:     /* Starting point */
1.126     brouard  10346:     
1.136     brouard  10347:     x = gsl_vector_alloc (NDIM);
                   10348:     
                   10349:     if (x == NULL){
                   10350:       gsl_vector_free(ss);
                   10351:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10352:     }
                   10353:   
                   10354:     /* Initialize method and iterate */
                   10355:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10356:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10357:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10358:     gsl_vector_set(x, 0, p[1]);
                   10359:     gsl_vector_set(x, 1, p[2]);
                   10360: 
                   10361:     minex_func.f = &gompertz_f;
                   10362:     minex_func.n = NDIM;
                   10363:     minex_func.params = (void *)&p; /* ??? */
                   10364:     
                   10365:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10366:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10367:     
                   10368:     printf("Iterations beginning .....\n\n");
                   10369:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10370: 
                   10371:     iteri=0;
                   10372:     while (rval == GSL_CONTINUE){
                   10373:       iteri++;
                   10374:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10375:       
                   10376:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10377:       fflush(0);
                   10378:       
                   10379:       if (status) 
                   10380:         break;
                   10381:       
                   10382:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10383:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10384:       
                   10385:       if (rval == GSL_SUCCESS)
                   10386:         printf ("converged to a local maximum at\n");
                   10387:       
                   10388:       printf("%5d ", iteri);
                   10389:       for (it = 0; it < NDIM; it++){
                   10390:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10391:       }
                   10392:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10393:     }
                   10394:     
                   10395:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10396:     
                   10397:     gsl_vector_free(x); /* initial values */
                   10398:     gsl_vector_free(ss); /* inital step size */
                   10399:     for (it=0; it<NDIM; it++){
                   10400:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10401:       fprintf(ficrespow," %.12lf", p[it]);
                   10402:     }
                   10403:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10404: #endif
                   10405: #ifdef POWELL
                   10406:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10407: #endif  
1.126     brouard  10408:     fclose(ficrespow);
                   10409:     
1.203     brouard  10410:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10411: 
                   10412:     for(i=1; i <=NDIM; i++)
                   10413:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10414:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10415:     
                   10416:     printf("\nCovariance matrix\n ");
1.203     brouard  10417:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10418:     for(i=1; i <=NDIM; i++) {
                   10419:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10420:                                printf("%f ",matcov[i][j]);
                   10421:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10422:       }
1.203     brouard  10423:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10424:     }
                   10425:     
                   10426:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10427:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10428:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10429:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10430:     }
1.126     brouard  10431:     lsurv=vector(1,AGESUP);
                   10432:     lpop=vector(1,AGESUP);
                   10433:     tpop=vector(1,AGESUP);
                   10434:     lsurv[agegomp]=100000;
                   10435:     
                   10436:     for (k=agegomp;k<=AGESUP;k++) {
                   10437:       agemortsup=k;
                   10438:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10439:     }
                   10440:     
                   10441:     for (k=agegomp;k<agemortsup;k++)
                   10442:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10443:     
                   10444:     for (k=agegomp;k<agemortsup;k++){
                   10445:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10446:       sumlpop=sumlpop+lpop[k];
                   10447:     }
                   10448:     
                   10449:     tpop[agegomp]=sumlpop;
                   10450:     for (k=agegomp;k<(agemortsup-3);k++){
                   10451:       /*  tpop[k+1]=2;*/
                   10452:       tpop[k+1]=tpop[k]-lpop[k];
                   10453:     }
                   10454:     
                   10455:     
                   10456:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10457:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10458:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10459:     
                   10460:     
                   10461:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10462:                ageminpar=50;
                   10463:                agemaxpar=100;
1.194     brouard  10464:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10465:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10466: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10467: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10468:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10469: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10470: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10471:     }else{
                   10472:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10473:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10474:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10475:                }
1.201     brouard  10476:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10477:                     stepm, weightopt,\
                   10478:                     model,imx,p,matcov,agemortsup);
                   10479:     
                   10480:     free_vector(lsurv,1,AGESUP);
                   10481:     free_vector(lpop,1,AGESUP);
                   10482:     free_vector(tpop,1,AGESUP);
1.220     brouard  10483:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10484:     free_ivector(cens,1,n);
                   10485:     free_vector(agecens,1,n);
                   10486:     free_ivector(dcwave,1,n);
1.220     brouard  10487: #ifdef GSL
1.136     brouard  10488: #endif
1.186     brouard  10489:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10490:   /* Standard  */
                   10491:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10492:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10493:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10494:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10495:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10496:     for (k=1; k<=npar;k++)
                   10497:       printf(" %d %8.5f",k,p[k]);
                   10498:     printf("\n");
1.205     brouard  10499:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10500:       /* mlikeli uses func not funcone */
                   10501:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10502:     }
                   10503:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10504:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10505:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10506:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10507:     }
                   10508:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10509:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10510:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10511:     for (k=1; k<=npar;k++)
                   10512:       printf(" %d %8.5f",k,p[k]);
                   10513:     printf("\n");
                   10514:     
                   10515:     /*--------- results files --------------*/
1.224     brouard  10516:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10517:     
                   10518:     
                   10519:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10520:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10521:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10522:     for(i=1,jk=1; i <=nlstate; i++){
                   10523:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10524:        if (k != i) {
                   10525:          printf("%d%d ",i,k);
                   10526:          fprintf(ficlog,"%d%d ",i,k);
                   10527:          fprintf(ficres,"%1d%1d ",i,k);
                   10528:          for(j=1; j <=ncovmodel; j++){
                   10529:            printf("%12.7f ",p[jk]);
                   10530:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10531:            fprintf(ficres,"%12.7f ",p[jk]);
                   10532:            jk++; 
                   10533:          }
                   10534:          printf("\n");
                   10535:          fprintf(ficlog,"\n");
                   10536:          fprintf(ficres,"\n");
                   10537:        }
1.126     brouard  10538:       }
                   10539:     }
1.203     brouard  10540:     if(mle != 0){
                   10541:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10542:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10543:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10544:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10545:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10546:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10547:        for(k=1; k <=(nlstate+ndeath); k++){
                   10548:          if (k != i) {
                   10549:            printf("%d%d ",i,k);
                   10550:            fprintf(ficlog,"%d%d ",i,k);
                   10551:            for(j=1; j <=ncovmodel; j++){
                   10552:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10553:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10554:              jk++; 
                   10555:            }
                   10556:            printf("\n");
                   10557:            fprintf(ficlog,"\n");
                   10558:          }
                   10559:        }
1.193     brouard  10560:       }
1.203     brouard  10561:     } /* end of hesscov and Wald tests */
1.225     brouard  10562:     
1.203     brouard  10563:     /*  */
1.126     brouard  10564:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10565:     printf("# Scales (for hessian or gradient estimation)\n");
                   10566:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10567:     for(i=1,jk=1; i <=nlstate; i++){
                   10568:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10569:        if (j!=i) {
                   10570:          fprintf(ficres,"%1d%1d",i,j);
                   10571:          printf("%1d%1d",i,j);
                   10572:          fprintf(ficlog,"%1d%1d",i,j);
                   10573:          for(k=1; k<=ncovmodel;k++){
                   10574:            printf(" %.5e",delti[jk]);
                   10575:            fprintf(ficlog," %.5e",delti[jk]);
                   10576:            fprintf(ficres," %.5e",delti[jk]);
                   10577:            jk++;
                   10578:          }
                   10579:          printf("\n");
                   10580:          fprintf(ficlog,"\n");
                   10581:          fprintf(ficres,"\n");
                   10582:        }
1.126     brouard  10583:       }
                   10584:     }
                   10585:     
                   10586:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  10587:     if(mle >= 1) /* To big for the screen */
1.126     brouard  10588:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10589:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   10590:     /* # 121 Var(a12)\n\ */
                   10591:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   10592:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   10593:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   10594:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   10595:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   10596:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   10597:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   10598:     
                   10599:     
                   10600:     /* Just to have a covariance matrix which will be more understandable
                   10601:        even is we still don't want to manage dictionary of variables
                   10602:     */
                   10603:     for(itimes=1;itimes<=2;itimes++){
                   10604:       jj=0;
                   10605:       for(i=1; i <=nlstate; i++){
1.225     brouard  10606:        for(j=1; j <=nlstate+ndeath; j++){
                   10607:          if(j==i) continue;
                   10608:          for(k=1; k<=ncovmodel;k++){
                   10609:            jj++;
                   10610:            ca[0]= k+'a'-1;ca[1]='\0';
                   10611:            if(itimes==1){
                   10612:              if(mle>=1)
                   10613:                printf("#%1d%1d%d",i,j,k);
                   10614:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   10615:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   10616:            }else{
                   10617:              if(mle>=1)
                   10618:                printf("%1d%1d%d",i,j,k);
                   10619:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   10620:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   10621:            }
                   10622:            ll=0;
                   10623:            for(li=1;li <=nlstate; li++){
                   10624:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   10625:                if(lj==li) continue;
                   10626:                for(lk=1;lk<=ncovmodel;lk++){
                   10627:                  ll++;
                   10628:                  if(ll<=jj){
                   10629:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   10630:                    if(ll<jj){
                   10631:                      if(itimes==1){
                   10632:                        if(mle>=1)
                   10633:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10634:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10635:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   10636:                      }else{
                   10637:                        if(mle>=1)
                   10638:                          printf(" %.5e",matcov[jj][ll]); 
                   10639:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   10640:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   10641:                      }
                   10642:                    }else{
                   10643:                      if(itimes==1){
                   10644:                        if(mle>=1)
                   10645:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   10646:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   10647:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   10648:                      }else{
                   10649:                        if(mle>=1)
                   10650:                          printf(" %.7e",matcov[jj][ll]); 
                   10651:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   10652:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   10653:                      }
                   10654:                    }
                   10655:                  }
                   10656:                } /* end lk */
                   10657:              } /* end lj */
                   10658:            } /* end li */
                   10659:            if(mle>=1)
                   10660:              printf("\n");
                   10661:            fprintf(ficlog,"\n");
                   10662:            fprintf(ficres,"\n");
                   10663:            numlinepar++;
                   10664:          } /* end k*/
                   10665:        } /*end j */
1.126     brouard  10666:       } /* end i */
                   10667:     } /* end itimes */
                   10668:     
                   10669:     fflush(ficlog);
                   10670:     fflush(ficres);
1.225     brouard  10671:     while(fgets(line, MAXLINE, ficpar)) {
                   10672:       /* If line starts with a # it is a comment */
                   10673:       if (line[0] == '#') {
                   10674:        numlinepar++;
                   10675:        fputs(line,stdout);
                   10676:        fputs(line,ficparo);
                   10677:        fputs(line,ficlog);
                   10678:        continue;
                   10679:       }else
                   10680:        break;
                   10681:     }
                   10682:     
1.209     brouard  10683:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   10684:     /*   ungetc(c,ficpar); */
                   10685:     /*   fgets(line, MAXLINE, ficpar); */
                   10686:     /*   fputs(line,stdout); */
                   10687:     /*   fputs(line,ficparo); */
                   10688:     /* } */
                   10689:     /* ungetc(c,ficpar); */
1.126     brouard  10690:     
                   10691:     estepm=0;
1.209     brouard  10692:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  10693:       
                   10694:       if (num_filled != 6) {
                   10695:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10696:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   10697:        goto end;
                   10698:       }
                   10699:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   10700:     }
                   10701:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   10702:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   10703:     
1.209     brouard  10704:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  10705:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   10706:     if (fage <= 2) {
                   10707:       bage = ageminpar;
                   10708:       fage = agemaxpar;
                   10709:     }
                   10710:     
                   10711:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  10712:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   10713:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  10714:                
1.186     brouard  10715:     /* Other stuffs, more or less useful */    
1.126     brouard  10716:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10717:       ungetc(c,ficpar);
                   10718:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10719:       fputs(line,stdout);
1.126     brouard  10720:       fputs(line,ficparo);
                   10721:     }
                   10722:     ungetc(c,ficpar);
                   10723:     
                   10724:     fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
                   10725:     fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10726:     fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10727:     printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10728:     fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   10729:     
                   10730:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10731:       ungetc(c,ficpar);
                   10732:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10733:       fputs(line,stdout);
1.126     brouard  10734:       fputs(line,ficparo);
                   10735:     }
                   10736:     ungetc(c,ficpar);
                   10737:     
                   10738:     
                   10739:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   10740:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   10741:     
                   10742:     fscanf(ficpar,"pop_based=%d\n",&popbased);
1.193     brouard  10743:     fprintf(ficlog,"pop_based=%d\n",popbased);
1.126     brouard  10744:     fprintf(ficparo,"pop_based=%d\n",popbased);   
                   10745:     fprintf(ficres,"pop_based=%d\n",popbased);   
                   10746:     
                   10747:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10748:       ungetc(c,ficpar);
                   10749:       fgets(line, MAXLINE, ficpar);
1.141     brouard  10750:       fputs(line,stdout);
1.126     brouard  10751:       fputs(line,ficparo);
                   10752:     }
                   10753:     ungetc(c,ficpar);
                   10754:     
                   10755:     fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
                   10756:     fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10757:     printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10758:     fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10759:     fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   10760:     /* day and month of proj2 are not used but only year anproj2.*/
                   10761:     
1.217     brouard  10762:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10763:       ungetc(c,ficpar);
                   10764:       fgets(line, MAXLINE, ficpar);
                   10765:       fputs(line,stdout);
                   10766:       fputs(line,ficparo);
                   10767:     }
                   10768:     ungetc(c,ficpar);
                   10769:     
                   10770:     fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);
1.223     brouard  10771:     fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10772:     fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   10773:     fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
1.217     brouard  10774:     /* day and month of proj2 are not used but only year anproj2.*/
1.126     brouard  10775:     
1.230     brouard  10776:     /* Results */
1.235     brouard  10777:     nresult=0;
1.230     brouard  10778:     while(fgets(line, MAXLINE, ficpar)) {
                   10779:       /* If line starts with a # it is a comment */
                   10780:       if (line[0] == '#') {
                   10781:        numlinepar++;
                   10782:        fputs(line,stdout);
                   10783:        fputs(line,ficparo);
                   10784:        fputs(line,ficlog);
                   10785:        continue;
                   10786:       }else
                   10787:        break;
                   10788:     }
                   10789:     while((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   10790:       if (num_filled == 0)
                   10791:        resultline[0]='\0';
                   10792:       else if (num_filled != 1){
                   10793:        printf("ERROR %d: result line should be at minimum 'result=' %s\n",num_filled, line);
                   10794:       }
1.235     brouard  10795:       nresult++; /* Sum of resultlines */
                   10796:       printf("Result %d: result=%s\n",nresult, resultline);
                   10797:       if(nresult > MAXRESULTLINES){
                   10798:        printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   10799:        fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   10800:        goto end;
                   10801:       }
                   10802:       decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.230     brouard  10803:       while(fgets(line, MAXLINE, ficpar)) {
                   10804:        /* If line starts with a # it is a comment */
                   10805:        if (line[0] == '#') {
                   10806:          numlinepar++;
                   10807:          fputs(line,stdout);
                   10808:          fputs(line,ficparo);
                   10809:          fputs(line,ficlog);
                   10810:          continue;
                   10811:        }else
                   10812:          break;
                   10813:       }
                   10814:       if (feof(ficpar))
                   10815:        break;
                   10816:       else{ /* Processess output results for this combination of covariate values */
                   10817:       }                                   
                   10818:     }
                   10819: 
                   10820: 
1.126     brouard  10821:     
1.230     brouard  10822:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  10823:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  10824:     
                   10825:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  10826:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  10827:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10828: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10829: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  10830:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  10831: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10832: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10833:     }else{
1.218     brouard  10834:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  10835:     }
                   10836:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.225     brouard  10837:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,prevfcast,backcast, estepm, \
                   10838:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  10839:                
1.225     brouard  10840:     /*------------ free_vector  -------------*/
                   10841:     /*  chdir(path); */
1.220     brouard  10842:                
1.215     brouard  10843:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   10844:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   10845:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   10846:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  10847:     free_lvector(num,1,n);
                   10848:     free_vector(agedc,1,n);
                   10849:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   10850:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   10851:     fclose(ficparo);
                   10852:     fclose(ficres);
1.220     brouard  10853:                
                   10854:                
1.186     brouard  10855:     /* Other results (useful)*/
1.220     brouard  10856:                
                   10857:                
1.126     brouard  10858:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  10859:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   10860:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  10861:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  10862:     fclose(ficrespl);
                   10863: 
                   10864:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  10865:     /*#include "hpijx.h"*/
                   10866:     hPijx(p, bage, fage);
1.145     brouard  10867:     fclose(ficrespij);
1.227     brouard  10868:     
1.220     brouard  10869:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  10870:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  10871:     k=1;
1.126     brouard  10872:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  10873:     
1.219     brouard  10874:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  10875:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  10876:     for(i=1;i<=AGESUP;i++)
1.219     brouard  10877:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  10878:        for(k=1;k<=ncovcombmax;k++)
                   10879:          probs[i][j][k]=0.;
1.219     brouard  10880:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   10881:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   10882:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  10883:       for(i=1;i<=AGESUP;i++)
                   10884:        for(j=1;j<=nlstate;j++)
                   10885:          for(k=1;k<=ncovcombmax;k++)
                   10886:            mobaverages[i][j][k]=0.;
1.219     brouard  10887:       mobaverage=mobaverages;
                   10888:       if (mobilav!=0) {
1.235     brouard  10889:        printf("Movingaveraging observed prevalence\n");
1.227     brouard  10890:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   10891:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   10892:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   10893:        }
1.219     brouard  10894:       }
                   10895:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   10896:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   10897:       else if (mobilavproj !=0) {
1.235     brouard  10898:        printf("Movingaveraging projected observed prevalence\n");
1.227     brouard  10899:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   10900:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   10901:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   10902:        }
1.219     brouard  10903:       }
                   10904:     }/* end if moving average */
1.227     brouard  10905:     
1.126     brouard  10906:     /*---------- Forecasting ------------------*/
                   10907:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   10908:     if(prevfcast==1){
                   10909:       /*    if(stepm ==1){*/
1.225     brouard  10910:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  10911:     }
1.217     brouard  10912:     if(backcast==1){
1.219     brouard  10913:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   10914:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   10915:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   10916: 
                   10917:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10918: 
                   10919:       bprlim=matrix(1,nlstate,1,nlstate);
                   10920:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   10921:       fclose(ficresplb);
                   10922: 
1.222     brouard  10923:       hBijx(p, bage, fage, mobaverage);
                   10924:       fclose(ficrespijb);
1.219     brouard  10925:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   10926: 
                   10927:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  10928:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  10929:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10930:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10931:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   10932:     }
1.217     brouard  10933:     
1.186     brouard  10934:  
                   10935:     /* ------ Other prevalence ratios------------ */
1.126     brouard  10936: 
1.215     brouard  10937:     free_ivector(wav,1,imx);
                   10938:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   10939:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   10940:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  10941:                
                   10942:                
1.127     brouard  10943:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  10944:                
1.201     brouard  10945:     strcpy(filerese,"E_");
                   10946:     strcat(filerese,fileresu);
1.126     brouard  10947:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   10948:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   10949:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   10950:     }
1.208     brouard  10951:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   10952:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.219     brouard  10953:                
1.235     brouard  10954:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   10955:     if (cptcovn < 1){i1=1;}
                   10956:     
                   10957:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10958:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   10959:       if(TKresult[nres]!= k)
                   10960:        continue;
1.219     brouard  10961:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  10962:       printf("\n#****** ");
1.225     brouard  10963:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  10964:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10965:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10966:       }
                   10967:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10968:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10969:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  10970:       }
                   10971:       fprintf(ficreseij,"******\n");
1.235     brouard  10972:       printf("******\n");
1.219     brouard  10973:       
                   10974:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   10975:       oldm=oldms;savm=savms;
1.235     brouard  10976:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  10977:       
1.219     brouard  10978:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  10979:     }
                   10980:     fclose(ficreseij);
1.208     brouard  10981:     printf("done evsij\n");fflush(stdout);
                   10982:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  10983:                
1.227     brouard  10984:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  10985:                
                   10986:                
1.201     brouard  10987:     strcpy(filerest,"T_");
                   10988:     strcat(filerest,fileresu);
1.127     brouard  10989:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   10990:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   10991:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   10992:     }
1.208     brouard  10993:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   10994:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  10995:                
1.126     brouard  10996: 
1.201     brouard  10997:     strcpy(fileresstde,"STDE_");
                   10998:     strcat(fileresstde,fileresu);
1.126     brouard  10999:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11000:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11001:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11002:     }
1.227     brouard  11003:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11004:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11005: 
1.201     brouard  11006:     strcpy(filerescve,"CVE_");
                   11007:     strcat(filerescve,fileresu);
1.126     brouard  11008:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11009:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11010:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11011:     }
1.227     brouard  11012:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11013:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11014: 
1.201     brouard  11015:     strcpy(fileresv,"V_");
                   11016:     strcat(fileresv,fileresu);
1.126     brouard  11017:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11018:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11019:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11020:     }
1.227     brouard  11021:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11022:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11023: 
1.145     brouard  11024:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11025:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11026:           
1.235     brouard  11027:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11028:     if (cptcovn < 1){i1=1;}
                   11029:     
                   11030:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11031:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
                   11032:       if(TKresult[nres]!= k)
                   11033:        continue;
                   11034:       printf("\n#****** Selected:");
                   11035:       fprintf(ficrest,"\n#****** Selected:");
                   11036:       fprintf(ficlog,"\n#****** Selected:");
1.227     brouard  11037:       for(j=1;j<=cptcoveff;j++){ 
                   11038:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11039:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11040:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11041:       }
1.235     brouard  11042:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11043:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11044:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11045:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11046:       }        
1.208     brouard  11047:       fprintf(ficrest,"******\n");
1.227     brouard  11048:       fprintf(ficlog,"******\n");
                   11049:       printf("******\n");
1.208     brouard  11050:       
                   11051:       fprintf(ficresstdeij,"\n#****** ");
                   11052:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11053:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11054:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11055:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11056:       }
1.235     brouard  11057:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11058:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11059:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11060:       }        
1.208     brouard  11061:       fprintf(ficresstdeij,"******\n");
                   11062:       fprintf(ficrescveij,"******\n");
                   11063:       
                   11064:       fprintf(ficresvij,"\n#****** ");
1.225     brouard  11065:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11066:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11067:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11068:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11069:       }        
1.208     brouard  11070:       fprintf(ficresvij,"******\n");
                   11071:       
                   11072:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11073:       oldm=oldms;savm=savms;
1.235     brouard  11074:       printf(" cvevsij ");
                   11075:       fprintf(ficlog, " cvevsij ");
                   11076:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11077:       printf(" end cvevsij \n ");
                   11078:       fprintf(ficlog, " end cvevsij \n ");
                   11079:       
                   11080:       /*
                   11081:        */
                   11082:       /* goto endfree; */
                   11083:       
                   11084:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11085:       pstamp(ficrest);
                   11086:       
                   11087:       
                   11088:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11089:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11090:        cptcod= 0; /* To be deleted */
                   11091:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11092:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11093:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11094:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11095:        if(vpopbased==1)
                   11096:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11097:        else
                   11098:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11099:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11100:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11101:        fprintf(ficrest,"\n");
                   11102:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11103:        epj=vector(1,nlstate+1);
                   11104:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11105:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11106:        for(age=bage; age <=fage ;age++){
1.235     brouard  11107:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11108:          if (vpopbased==1) {
                   11109:            if(mobilav ==0){
                   11110:              for(i=1; i<=nlstate;i++)
                   11111:                prlim[i][i]=probs[(int)age][i][k];
                   11112:            }else{ /* mobilav */ 
                   11113:              for(i=1; i<=nlstate;i++)
                   11114:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11115:            }
                   11116:          }
1.219     brouard  11117:          
1.227     brouard  11118:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11119:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11120:          /* printf(" age %4.0f ",age); */
                   11121:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11122:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11123:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11124:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11125:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11126:            }
                   11127:            epj[nlstate+1] +=epj[j];
                   11128:          }
                   11129:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11130:          
1.227     brouard  11131:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11132:            for(j=1;j <=nlstate;j++)
                   11133:              vepp += vareij[i][j][(int)age];
                   11134:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11135:          for(j=1;j <=nlstate;j++){
                   11136:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11137:          }
                   11138:          fprintf(ficrest,"\n");
                   11139:        }
1.208     brouard  11140:       } /* End vpopbased */
                   11141:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11142:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11143:       free_vector(epj,1,nlstate+1);
1.235     brouard  11144:       printf("done selection\n");fflush(stdout);
                   11145:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11146:       
1.145     brouard  11147:       /*}*/
1.235     brouard  11148:     } /* End k selection */
1.227     brouard  11149: 
                   11150:     printf("done State-specific expectancies\n");fflush(stdout);
                   11151:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11152: 
1.126     brouard  11153:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11154:     
1.201     brouard  11155:     strcpy(fileresvpl,"VPL_");
                   11156:     strcat(fileresvpl,fileresu);
1.126     brouard  11157:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11158:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11159:       exit(0);
                   11160:     }
1.208     brouard  11161:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11162:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11163:     
1.145     brouard  11164:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11165:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11166:     
1.235     brouard  11167:     i1=pow(2,cptcoveff);
                   11168:     if (cptcovn < 1){i1=1;}
                   11169: 
                   11170:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11171:     for(k=1; k<=i1;k++){
                   11172:       if(TKresult[nres]!= k)
                   11173:        continue;
1.227     brouard  11174:       fprintf(ficresvpl,"\n#****** ");
                   11175:       printf("\n#****** ");
                   11176:       fprintf(ficlog,"\n#****** ");
                   11177:       for(j=1;j<=cptcoveff;j++) {
                   11178:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11179:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11180:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11181:       }
1.235     brouard  11182:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11183:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11184:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11185:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11186:       }        
1.227     brouard  11187:       fprintf(ficresvpl,"******\n");
                   11188:       printf("******\n");
                   11189:       fprintf(ficlog,"******\n");
                   11190:       
                   11191:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11192:       oldm=oldms;savm=savms;
1.235     brouard  11193:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11194:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11195:       /*}*/
1.126     brouard  11196:     }
1.227     brouard  11197:     
1.126     brouard  11198:     fclose(ficresvpl);
1.208     brouard  11199:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11200:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11201:     
                   11202:     free_vector(weight,1,n);
                   11203:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11204:     free_imatrix(s,1,maxwav+1,1,n);
                   11205:     free_matrix(anint,1,maxwav,1,n); 
                   11206:     free_matrix(mint,1,maxwav,1,n);
                   11207:     free_ivector(cod,1,n);
                   11208:     free_ivector(tab,1,NCOVMAX);
                   11209:     fclose(ficresstdeij);
                   11210:     fclose(ficrescveij);
                   11211:     fclose(ficresvij);
                   11212:     fclose(ficrest);
                   11213:     fclose(ficpar);
                   11214:     
                   11215:     
1.126     brouard  11216:     /*---------- End : free ----------------*/
1.219     brouard  11217:     if (mobilav!=0 ||mobilavproj !=0)
                   11218:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11219:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11220:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11221:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11222:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11223:   /* endfree:*/
                   11224:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11225:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11226:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11227:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11228:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11229:   free_matrix(coqvar,1,maxwav,1,n);
                   11230:   free_matrix(covar,0,NCOVMAX,1,n);
                   11231:   free_matrix(matcov,1,npar,1,npar);
                   11232:   free_matrix(hess,1,npar,1,npar);
                   11233:   /*free_vector(delti,1,npar);*/
                   11234:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11235:   free_matrix(agev,1,maxwav,1,imx);
                   11236:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11237:   
                   11238:   free_ivector(ncodemax,1,NCOVMAX);
                   11239:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11240:   free_ivector(Dummy,-1,NCOVMAX);
                   11241:   free_ivector(Fixed,-1,NCOVMAX);
                   11242:   free_ivector(Typevar,-1,NCOVMAX);
                   11243:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11244:   free_ivector(TvarsQ,1,NCOVMAX);
                   11245:   free_ivector(TvarsQind,1,NCOVMAX);
                   11246:   free_ivector(TvarsD,1,NCOVMAX);
                   11247:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11248:   free_ivector(TvarFD,1,NCOVMAX);
                   11249:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11250:   free_ivector(TvarF,1,NCOVMAX);
                   11251:   free_ivector(TvarFind,1,NCOVMAX);
                   11252:   free_ivector(TvarV,1,NCOVMAX);
                   11253:   free_ivector(TvarVind,1,NCOVMAX);
                   11254:   free_ivector(TvarA,1,NCOVMAX);
                   11255:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11256:   free_ivector(TvarFQ,1,NCOVMAX);
                   11257:   free_ivector(TvarFQind,1,NCOVMAX);
                   11258:   free_ivector(TvarVD,1,NCOVMAX);
                   11259:   free_ivector(TvarVDind,1,NCOVMAX);
                   11260:   free_ivector(TvarVQ,1,NCOVMAX);
                   11261:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11262:   free_ivector(Tvarsel,1,NCOVMAX);
                   11263:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11264:   free_ivector(Tposprod,1,NCOVMAX);
                   11265:   free_ivector(Tprod,1,NCOVMAX);
                   11266:   free_ivector(Tvaraff,1,NCOVMAX);
                   11267:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11268:   free_ivector(Tage,1,NCOVMAX);
                   11269:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11270:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11271:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11272:   
                   11273:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11274:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11275:   fflush(fichtm);
                   11276:   fflush(ficgp);
                   11277:   
1.227     brouard  11278:   
1.126     brouard  11279:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11280:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11281:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11282:   }else{
                   11283:     printf("End of Imach\n");
                   11284:     fprintf(ficlog,"End of Imach\n");
                   11285:   }
                   11286:   printf("See log file on %s\n",filelog);
                   11287:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11288:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11289:   rend_time = time(NULL);  
                   11290:   end_time = *localtime(&rend_time);
                   11291:   /* tml = *localtime(&end_time.tm_sec); */
                   11292:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11293:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11294:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11295:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11296:   
1.157     brouard  11297:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11298:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11299:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11300:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11301: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11302:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11303:   fclose(fichtm);
                   11304:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11305:   fclose(fichtmcov);
                   11306:   fclose(ficgp);
                   11307:   fclose(ficlog);
                   11308:   /*------ End -----------*/
1.227     brouard  11309:   
                   11310:   
                   11311:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11312: #ifdef WIN32
1.227     brouard  11313:   if (_chdir(pathcd) != 0)
                   11314:     printf("Can't move to directory %s!\n",path);
                   11315:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11316: #else
1.227     brouard  11317:     if(chdir(pathcd) != 0)
                   11318:       printf("Can't move to directory %s!\n", path);
                   11319:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11320: #endif 
1.126     brouard  11321:     printf("Current directory %s!\n",pathcd);
                   11322:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11323:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11324: #ifdef _WIN32
1.126     brouard  11325:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11326: #endif
                   11327:   if(!stat(plotcmd,&info)){
1.158     brouard  11328:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11329:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11330:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11331:     }else
                   11332:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11333: #ifdef __unix
1.126     brouard  11334:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11335:     if(!stat(plotcmd,&info)){
1.158     brouard  11336:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11337:     }else
                   11338:       strcpy(pplotcmd,plotcmd);
                   11339: #endif
                   11340:   }else
                   11341:     strcpy(pplotcmd,plotcmd);
                   11342:   
                   11343:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11344:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11345:   
1.126     brouard  11346:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11347:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11348:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11349:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11350:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11351:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11352:   }
1.158     brouard  11353:   printf(" Successful, please wait...");
1.126     brouard  11354:   while (z[0] != 'q') {
                   11355:     /* chdir(path); */
1.154     brouard  11356:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11357:     scanf("%s",z);
                   11358: /*     if (z[0] == 'c') system("./imach"); */
                   11359:     if (z[0] == 'e') {
1.158     brouard  11360: #ifdef __APPLE__
1.152     brouard  11361:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11362: #elif __linux
                   11363:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11364: #else
1.152     brouard  11365:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11366: #endif
                   11367:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11368:       system(pplotcmd);
1.126     brouard  11369:     }
                   11370:     else if (z[0] == 'g') system(plotcmd);
                   11371:     else if (z[0] == 'q') exit(0);
                   11372:   }
1.227     brouard  11373: end:
1.126     brouard  11374:   while (z[0] != 'q') {
1.195     brouard  11375:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11376:     scanf("%s",z);
                   11377:   }
                   11378: }

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