Annotation of imach/src/imach.c, revision 1.258

1.258   ! brouard     1: /* $Id: imach.c,v 1.257 2017/03/29 16:53:30 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.258   ! brouard     4:   Revision 1.257  2017/03/29 16:53:30  brouard
        !             5:   Summary: Temp
        !             6: 
1.257     brouard     7:   Revision 1.256  2017/03/27 05:50:23  brouard
                      8:   Summary: Temporary
                      9: 
1.256     brouard    10:   Revision 1.255  2017/03/08 16:02:28  brouard
                     11:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     12: 
1.255     brouard    13:   Revision 1.254  2017/03/08 07:13:00  brouard
                     14:   Summary: Fixing data parameter line
                     15: 
1.254     brouard    16:   Revision 1.253  2016/12/15 11:59:41  brouard
                     17:   Summary: 0.99 in progress
                     18: 
1.253     brouard    19:   Revision 1.252  2016/09/15 21:15:37  brouard
                     20:   *** empty log message ***
                     21: 
1.252     brouard    22:   Revision 1.251  2016/09/15 15:01:13  brouard
                     23:   Summary: not working
                     24: 
1.251     brouard    25:   Revision 1.250  2016/09/08 16:07:27  brouard
                     26:   Summary: continue
                     27: 
1.250     brouard    28:   Revision 1.249  2016/09/07 17:14:18  brouard
                     29:   Summary: Starting values from frequencies
                     30: 
1.249     brouard    31:   Revision 1.248  2016/09/07 14:10:18  brouard
                     32:   *** empty log message ***
                     33: 
1.248     brouard    34:   Revision 1.247  2016/09/02 11:11:21  brouard
                     35:   *** empty log message ***
                     36: 
1.247     brouard    37:   Revision 1.246  2016/09/02 08:49:22  brouard
                     38:   *** empty log message ***
                     39: 
1.246     brouard    40:   Revision 1.245  2016/09/02 07:25:01  brouard
                     41:   *** empty log message ***
                     42: 
1.245     brouard    43:   Revision 1.244  2016/09/02 07:17:34  brouard
                     44:   *** empty log message ***
                     45: 
1.244     brouard    46:   Revision 1.243  2016/09/02 06:45:35  brouard
                     47:   *** empty log message ***
                     48: 
1.243     brouard    49:   Revision 1.242  2016/08/30 15:01:20  brouard
                     50:   Summary: Fixing a lots
                     51: 
1.242     brouard    52:   Revision 1.241  2016/08/29 17:17:25  brouard
                     53:   Summary: gnuplot problem in Back projection to fix
                     54: 
1.241     brouard    55:   Revision 1.240  2016/08/29 07:53:18  brouard
                     56:   Summary: Better
                     57: 
1.240     brouard    58:   Revision 1.239  2016/08/26 15:51:03  brouard
                     59:   Summary: Improvement in Powell output in order to copy and paste
                     60: 
                     61:   Author:
                     62: 
1.239     brouard    63:   Revision 1.238  2016/08/26 14:23:35  brouard
                     64:   Summary: Starting tests of 0.99
                     65: 
1.238     brouard    66:   Revision 1.237  2016/08/26 09:20:19  brouard
                     67:   Summary: to valgrind
                     68: 
1.237     brouard    69:   Revision 1.236  2016/08/25 10:50:18  brouard
                     70:   *** empty log message ***
                     71: 
1.236     brouard    72:   Revision 1.235  2016/08/25 06:59:23  brouard
                     73:   *** empty log message ***
                     74: 
1.235     brouard    75:   Revision 1.234  2016/08/23 16:51:20  brouard
                     76:   *** empty log message ***
                     77: 
1.234     brouard    78:   Revision 1.233  2016/08/23 07:40:50  brouard
                     79:   Summary: not working
                     80: 
1.233     brouard    81:   Revision 1.232  2016/08/22 14:20:21  brouard
                     82:   Summary: not working
                     83: 
1.232     brouard    84:   Revision 1.231  2016/08/22 07:17:15  brouard
                     85:   Summary: not working
                     86: 
1.231     brouard    87:   Revision 1.230  2016/08/22 06:55:53  brouard
                     88:   Summary: Not working
                     89: 
1.230     brouard    90:   Revision 1.229  2016/07/23 09:45:53  brouard
                     91:   Summary: Completing for func too
                     92: 
1.229     brouard    93:   Revision 1.228  2016/07/22 17:45:30  brouard
                     94:   Summary: Fixing some arrays, still debugging
                     95: 
1.227     brouard    96:   Revision 1.226  2016/07/12 18:42:34  brouard
                     97:   Summary: temp
                     98: 
1.226     brouard    99:   Revision 1.225  2016/07/12 08:40:03  brouard
                    100:   Summary: saving but not running
                    101: 
1.225     brouard   102:   Revision 1.224  2016/07/01 13:16:01  brouard
                    103:   Summary: Fixes
                    104: 
1.224     brouard   105:   Revision 1.223  2016/02/19 09:23:35  brouard
                    106:   Summary: temporary
                    107: 
1.223     brouard   108:   Revision 1.222  2016/02/17 08:14:50  brouard
                    109:   Summary: Probably last 0.98 stable version 0.98r6
                    110: 
1.222     brouard   111:   Revision 1.221  2016/02/15 23:35:36  brouard
                    112:   Summary: minor bug
                    113: 
1.220     brouard   114:   Revision 1.219  2016/02/15 00:48:12  brouard
                    115:   *** empty log message ***
                    116: 
1.219     brouard   117:   Revision 1.218  2016/02/12 11:29:23  brouard
                    118:   Summary: 0.99 Back projections
                    119: 
1.218     brouard   120:   Revision 1.217  2015/12/23 17:18:31  brouard
                    121:   Summary: Experimental backcast
                    122: 
1.217     brouard   123:   Revision 1.216  2015/12/18 17:32:11  brouard
                    124:   Summary: 0.98r4 Warning and status=-2
                    125: 
                    126:   Version 0.98r4 is now:
                    127:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    128:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    129:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    130: 
1.216     brouard   131:   Revision 1.215  2015/12/16 08:52:24  brouard
                    132:   Summary: 0.98r4 working
                    133: 
1.215     brouard   134:   Revision 1.214  2015/12/16 06:57:54  brouard
                    135:   Summary: temporary not working
                    136: 
1.214     brouard   137:   Revision 1.213  2015/12/11 18:22:17  brouard
                    138:   Summary: 0.98r4
                    139: 
1.213     brouard   140:   Revision 1.212  2015/11/21 12:47:24  brouard
                    141:   Summary: minor typo
                    142: 
1.212     brouard   143:   Revision 1.211  2015/11/21 12:41:11  brouard
                    144:   Summary: 0.98r3 with some graph of projected cross-sectional
                    145: 
                    146:   Author: Nicolas Brouard
                    147: 
1.211     brouard   148:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   149:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   150:   Summary: Adding ftolpl parameter
                    151:   Author: N Brouard
                    152: 
                    153:   We had difficulties to get smoothed confidence intervals. It was due
                    154:   to the period prevalence which wasn't computed accurately. The inner
                    155:   parameter ftolpl is now an outer parameter of the .imach parameter
                    156:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    157:   computation are long.
                    158: 
1.209     brouard   159:   Revision 1.208  2015/11/17 14:31:57  brouard
                    160:   Summary: temporary
                    161: 
1.208     brouard   162:   Revision 1.207  2015/10/27 17:36:57  brouard
                    163:   *** empty log message ***
                    164: 
1.207     brouard   165:   Revision 1.206  2015/10/24 07:14:11  brouard
                    166:   *** empty log message ***
                    167: 
1.206     brouard   168:   Revision 1.205  2015/10/23 15:50:53  brouard
                    169:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    170: 
1.205     brouard   171:   Revision 1.204  2015/10/01 16:20:26  brouard
                    172:   Summary: Some new graphs of contribution to likelihood
                    173: 
1.204     brouard   174:   Revision 1.203  2015/09/30 17:45:14  brouard
                    175:   Summary: looking at better estimation of the hessian
                    176: 
                    177:   Also a better criteria for convergence to the period prevalence And
                    178:   therefore adding the number of years needed to converge. (The
                    179:   prevalence in any alive state shold sum to one
                    180: 
1.203     brouard   181:   Revision 1.202  2015/09/22 19:45:16  brouard
                    182:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    183: 
1.202     brouard   184:   Revision 1.201  2015/09/15 17:34:58  brouard
                    185:   Summary: 0.98r0
                    186: 
                    187:   - Some new graphs like suvival functions
                    188:   - Some bugs fixed like model=1+age+V2.
                    189: 
1.201     brouard   190:   Revision 1.200  2015/09/09 16:53:55  brouard
                    191:   Summary: Big bug thanks to Flavia
                    192: 
                    193:   Even model=1+age+V2. did not work anymore
                    194: 
1.200     brouard   195:   Revision 1.199  2015/09/07 14:09:23  brouard
                    196:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    197: 
1.199     brouard   198:   Revision 1.198  2015/09/03 07:14:39  brouard
                    199:   Summary: 0.98q5 Flavia
                    200: 
1.198     brouard   201:   Revision 1.197  2015/09/01 18:24:39  brouard
                    202:   *** empty log message ***
                    203: 
1.197     brouard   204:   Revision 1.196  2015/08/18 23:17:52  brouard
                    205:   Summary: 0.98q5
                    206: 
1.196     brouard   207:   Revision 1.195  2015/08/18 16:28:39  brouard
                    208:   Summary: Adding a hack for testing purpose
                    209: 
                    210:   After reading the title, ftol and model lines, if the comment line has
                    211:   a q, starting with #q, the answer at the end of the run is quit. It
                    212:   permits to run test files in batch with ctest. The former workaround was
                    213:   $ echo q | imach foo.imach
                    214: 
1.195     brouard   215:   Revision 1.194  2015/08/18 13:32:00  brouard
                    216:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    217: 
1.194     brouard   218:   Revision 1.193  2015/08/04 07:17:42  brouard
                    219:   Summary: 0.98q4
                    220: 
1.193     brouard   221:   Revision 1.192  2015/07/16 16:49:02  brouard
                    222:   Summary: Fixing some outputs
                    223: 
1.192     brouard   224:   Revision 1.191  2015/07/14 10:00:33  brouard
                    225:   Summary: Some fixes
                    226: 
1.191     brouard   227:   Revision 1.190  2015/05/05 08:51:13  brouard
                    228:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    229: 
                    230:   Fix 1+age+.
                    231: 
1.190     brouard   232:   Revision 1.189  2015/04/30 14:45:16  brouard
                    233:   Summary: 0.98q2
                    234: 
1.189     brouard   235:   Revision 1.188  2015/04/30 08:27:53  brouard
                    236:   *** empty log message ***
                    237: 
1.188     brouard   238:   Revision 1.187  2015/04/29 09:11:15  brouard
                    239:   *** empty log message ***
                    240: 
1.187     brouard   241:   Revision 1.186  2015/04/23 12:01:52  brouard
                    242:   Summary: V1*age is working now, version 0.98q1
                    243: 
                    244:   Some codes had been disabled in order to simplify and Vn*age was
                    245:   working in the optimization phase, ie, giving correct MLE parameters,
                    246:   but, as usual, outputs were not correct and program core dumped.
                    247: 
1.186     brouard   248:   Revision 1.185  2015/03/11 13:26:42  brouard
                    249:   Summary: Inclusion of compile and links command line for Intel Compiler
                    250: 
1.185     brouard   251:   Revision 1.184  2015/03/11 11:52:39  brouard
                    252:   Summary: Back from Windows 8. Intel Compiler
                    253: 
1.184     brouard   254:   Revision 1.183  2015/03/10 20:34:32  brouard
                    255:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    256: 
                    257:   We use directest instead of original Powell test; probably no
                    258:   incidence on the results, but better justifications;
                    259:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    260:   wrong results.
                    261: 
1.183     brouard   262:   Revision 1.182  2015/02/12 08:19:57  brouard
                    263:   Summary: Trying to keep directest which seems simpler and more general
                    264:   Author: Nicolas Brouard
                    265: 
1.182     brouard   266:   Revision 1.181  2015/02/11 23:22:24  brouard
                    267:   Summary: Comments on Powell added
                    268: 
                    269:   Author:
                    270: 
1.181     brouard   271:   Revision 1.180  2015/02/11 17:33:45  brouard
                    272:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    273: 
1.180     brouard   274:   Revision 1.179  2015/01/04 09:57:06  brouard
                    275:   Summary: back to OS/X
                    276: 
1.179     brouard   277:   Revision 1.178  2015/01/04 09:35:48  brouard
                    278:   *** empty log message ***
                    279: 
1.178     brouard   280:   Revision 1.177  2015/01/03 18:40:56  brouard
                    281:   Summary: Still testing ilc32 on OSX
                    282: 
1.177     brouard   283:   Revision 1.176  2015/01/03 16:45:04  brouard
                    284:   *** empty log message ***
                    285: 
1.176     brouard   286:   Revision 1.175  2015/01/03 16:33:42  brouard
                    287:   *** empty log message ***
                    288: 
1.175     brouard   289:   Revision 1.174  2015/01/03 16:15:49  brouard
                    290:   Summary: Still in cross-compilation
                    291: 
1.174     brouard   292:   Revision 1.173  2015/01/03 12:06:26  brouard
                    293:   Summary: trying to detect cross-compilation
                    294: 
1.173     brouard   295:   Revision 1.172  2014/12/27 12:07:47  brouard
                    296:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    297: 
1.172     brouard   298:   Revision 1.171  2014/12/23 13:26:59  brouard
                    299:   Summary: Back from Visual C
                    300: 
                    301:   Still problem with utsname.h on Windows
                    302: 
1.171     brouard   303:   Revision 1.170  2014/12/23 11:17:12  brouard
                    304:   Summary: Cleaning some \%% back to %%
                    305: 
                    306:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    307: 
1.170     brouard   308:   Revision 1.169  2014/12/22 23:08:31  brouard
                    309:   Summary: 0.98p
                    310: 
                    311:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    312: 
1.169     brouard   313:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   314:   Summary: update
1.169     brouard   315: 
1.168     brouard   316:   Revision 1.167  2014/12/22 13:50:56  brouard
                    317:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    318: 
                    319:   Testing on Linux 64
                    320: 
1.167     brouard   321:   Revision 1.166  2014/12/22 11:40:47  brouard
                    322:   *** empty log message ***
                    323: 
1.166     brouard   324:   Revision 1.165  2014/12/16 11:20:36  brouard
                    325:   Summary: After compiling on Visual C
                    326: 
                    327:   * imach.c (Module): Merging 1.61 to 1.162
                    328: 
1.165     brouard   329:   Revision 1.164  2014/12/16 10:52:11  brouard
                    330:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    331: 
                    332:   * imach.c (Module): Merging 1.61 to 1.162
                    333: 
1.164     brouard   334:   Revision 1.163  2014/12/16 10:30:11  brouard
                    335:   * imach.c (Module): Merging 1.61 to 1.162
                    336: 
1.163     brouard   337:   Revision 1.162  2014/09/25 11:43:39  brouard
                    338:   Summary: temporary backup 0.99!
                    339: 
1.162     brouard   340:   Revision 1.1  2014/09/16 11:06:58  brouard
                    341:   Summary: With some code (wrong) for nlopt
                    342: 
                    343:   Author:
                    344: 
                    345:   Revision 1.161  2014/09/15 20:41:41  brouard
                    346:   Summary: Problem with macro SQR on Intel compiler
                    347: 
1.161     brouard   348:   Revision 1.160  2014/09/02 09:24:05  brouard
                    349:   *** empty log message ***
                    350: 
1.160     brouard   351:   Revision 1.159  2014/09/01 10:34:10  brouard
                    352:   Summary: WIN32
                    353:   Author: Brouard
                    354: 
1.159     brouard   355:   Revision 1.158  2014/08/27 17:11:51  brouard
                    356:   *** empty log message ***
                    357: 
1.158     brouard   358:   Revision 1.157  2014/08/27 16:26:55  brouard
                    359:   Summary: Preparing windows Visual studio version
                    360:   Author: Brouard
                    361: 
                    362:   In order to compile on Visual studio, time.h is now correct and time_t
                    363:   and tm struct should be used. difftime should be used but sometimes I
                    364:   just make the differences in raw time format (time(&now).
                    365:   Trying to suppress #ifdef LINUX
                    366:   Add xdg-open for __linux in order to open default browser.
                    367: 
1.157     brouard   368:   Revision 1.156  2014/08/25 20:10:10  brouard
                    369:   *** empty log message ***
                    370: 
1.156     brouard   371:   Revision 1.155  2014/08/25 18:32:34  brouard
                    372:   Summary: New compile, minor changes
                    373:   Author: Brouard
                    374: 
1.155     brouard   375:   Revision 1.154  2014/06/20 17:32:08  brouard
                    376:   Summary: Outputs now all graphs of convergence to period prevalence
                    377: 
1.154     brouard   378:   Revision 1.153  2014/06/20 16:45:46  brouard
                    379:   Summary: If 3 live state, convergence to period prevalence on same graph
                    380:   Author: Brouard
                    381: 
1.153     brouard   382:   Revision 1.152  2014/06/18 17:54:09  brouard
                    383:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    384: 
1.152     brouard   385:   Revision 1.151  2014/06/18 16:43:30  brouard
                    386:   *** empty log message ***
                    387: 
1.151     brouard   388:   Revision 1.150  2014/06/18 16:42:35  brouard
                    389:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    390:   Author: brouard
                    391: 
1.150     brouard   392:   Revision 1.149  2014/06/18 15:51:14  brouard
                    393:   Summary: Some fixes in parameter files errors
                    394:   Author: Nicolas Brouard
                    395: 
1.149     brouard   396:   Revision 1.148  2014/06/17 17:38:48  brouard
                    397:   Summary: Nothing new
                    398:   Author: Brouard
                    399: 
                    400:   Just a new packaging for OS/X version 0.98nS
                    401: 
1.148     brouard   402:   Revision 1.147  2014/06/16 10:33:11  brouard
                    403:   *** empty log message ***
                    404: 
1.147     brouard   405:   Revision 1.146  2014/06/16 10:20:28  brouard
                    406:   Summary: Merge
                    407:   Author: Brouard
                    408: 
                    409:   Merge, before building revised version.
                    410: 
1.146     brouard   411:   Revision 1.145  2014/06/10 21:23:15  brouard
                    412:   Summary: Debugging with valgrind
                    413:   Author: Nicolas Brouard
                    414: 
                    415:   Lot of changes in order to output the results with some covariates
                    416:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    417:   improve the code.
                    418:   No more memory valgrind error but a lot has to be done in order to
                    419:   continue the work of splitting the code into subroutines.
                    420:   Also, decodemodel has been improved. Tricode is still not
                    421:   optimal. nbcode should be improved. Documentation has been added in
                    422:   the source code.
                    423: 
1.144     brouard   424:   Revision 1.143  2014/01/26 09:45:38  brouard
                    425:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    426: 
                    427:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    428:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    429: 
1.143     brouard   430:   Revision 1.142  2014/01/26 03:57:36  brouard
                    431:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    432: 
                    433:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    434: 
1.142     brouard   435:   Revision 1.141  2014/01/26 02:42:01  brouard
                    436:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    437: 
1.141     brouard   438:   Revision 1.140  2011/09/02 10:37:54  brouard
                    439:   Summary: times.h is ok with mingw32 now.
                    440: 
1.140     brouard   441:   Revision 1.139  2010/06/14 07:50:17  brouard
                    442:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    443:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    444: 
1.139     brouard   445:   Revision 1.138  2010/04/30 18:19:40  brouard
                    446:   *** empty log message ***
                    447: 
1.138     brouard   448:   Revision 1.137  2010/04/29 18:11:38  brouard
                    449:   (Module): Checking covariates for more complex models
                    450:   than V1+V2. A lot of change to be done. Unstable.
                    451: 
1.137     brouard   452:   Revision 1.136  2010/04/26 20:30:53  brouard
                    453:   (Module): merging some libgsl code. Fixing computation
                    454:   of likelione (using inter/intrapolation if mle = 0) in order to
                    455:   get same likelihood as if mle=1.
                    456:   Some cleaning of code and comments added.
                    457: 
1.136     brouard   458:   Revision 1.135  2009/10/29 15:33:14  brouard
                    459:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    460: 
1.135     brouard   461:   Revision 1.134  2009/10/29 13:18:53  brouard
                    462:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    463: 
1.134     brouard   464:   Revision 1.133  2009/07/06 10:21:25  brouard
                    465:   just nforces
                    466: 
1.133     brouard   467:   Revision 1.132  2009/07/06 08:22:05  brouard
                    468:   Many tings
                    469: 
1.132     brouard   470:   Revision 1.131  2009/06/20 16:22:47  brouard
                    471:   Some dimensions resccaled
                    472: 
1.131     brouard   473:   Revision 1.130  2009/05/26 06:44:34  brouard
                    474:   (Module): Max Covariate is now set to 20 instead of 8. A
                    475:   lot of cleaning with variables initialized to 0. Trying to make
                    476:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    477: 
1.130     brouard   478:   Revision 1.129  2007/08/31 13:49:27  lievre
                    479:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    480: 
1.129     lievre    481:   Revision 1.128  2006/06/30 13:02:05  brouard
                    482:   (Module): Clarifications on computing e.j
                    483: 
1.128     brouard   484:   Revision 1.127  2006/04/28 18:11:50  brouard
                    485:   (Module): Yes the sum of survivors was wrong since
                    486:   imach-114 because nhstepm was no more computed in the age
                    487:   loop. Now we define nhstepma in the age loop.
                    488:   (Module): In order to speed up (in case of numerous covariates) we
                    489:   compute health expectancies (without variances) in a first step
                    490:   and then all the health expectancies with variances or standard
                    491:   deviation (needs data from the Hessian matrices) which slows the
                    492:   computation.
                    493:   In the future we should be able to stop the program is only health
                    494:   expectancies and graph are needed without standard deviations.
                    495: 
1.127     brouard   496:   Revision 1.126  2006/04/28 17:23:28  brouard
                    497:   (Module): Yes the sum of survivors was wrong since
                    498:   imach-114 because nhstepm was no more computed in the age
                    499:   loop. Now we define nhstepma in the age loop.
                    500:   Version 0.98h
                    501: 
1.126     brouard   502:   Revision 1.125  2006/04/04 15:20:31  lievre
                    503:   Errors in calculation of health expectancies. Age was not initialized.
                    504:   Forecasting file added.
                    505: 
                    506:   Revision 1.124  2006/03/22 17:13:53  lievre
                    507:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    508:   The log-likelihood is printed in the log file
                    509: 
                    510:   Revision 1.123  2006/03/20 10:52:43  brouard
                    511:   * imach.c (Module): <title> changed, corresponds to .htm file
                    512:   name. <head> headers where missing.
                    513: 
                    514:   * imach.c (Module): Weights can have a decimal point as for
                    515:   English (a comma might work with a correct LC_NUMERIC environment,
                    516:   otherwise the weight is truncated).
                    517:   Modification of warning when the covariates values are not 0 or
                    518:   1.
                    519:   Version 0.98g
                    520: 
                    521:   Revision 1.122  2006/03/20 09:45:41  brouard
                    522:   (Module): Weights can have a decimal point as for
                    523:   English (a comma might work with a correct LC_NUMERIC environment,
                    524:   otherwise the weight is truncated).
                    525:   Modification of warning when the covariates values are not 0 or
                    526:   1.
                    527:   Version 0.98g
                    528: 
                    529:   Revision 1.121  2006/03/16 17:45:01  lievre
                    530:   * imach.c (Module): Comments concerning covariates added
                    531: 
                    532:   * imach.c (Module): refinements in the computation of lli if
                    533:   status=-2 in order to have more reliable computation if stepm is
                    534:   not 1 month. Version 0.98f
                    535: 
                    536:   Revision 1.120  2006/03/16 15:10:38  lievre
                    537:   (Module): refinements in the computation of lli if
                    538:   status=-2 in order to have more reliable computation if stepm is
                    539:   not 1 month. Version 0.98f
                    540: 
                    541:   Revision 1.119  2006/03/15 17:42:26  brouard
                    542:   (Module): Bug if status = -2, the loglikelihood was
                    543:   computed as likelihood omitting the logarithm. Version O.98e
                    544: 
                    545:   Revision 1.118  2006/03/14 18:20:07  brouard
                    546:   (Module): varevsij Comments added explaining the second
                    547:   table of variances if popbased=1 .
                    548:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    549:   (Module): Function pstamp added
                    550:   (Module): Version 0.98d
                    551: 
                    552:   Revision 1.117  2006/03/14 17:16:22  brouard
                    553:   (Module): varevsij Comments added explaining the second
                    554:   table of variances if popbased=1 .
                    555:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    556:   (Module): Function pstamp added
                    557:   (Module): Version 0.98d
                    558: 
                    559:   Revision 1.116  2006/03/06 10:29:27  brouard
                    560:   (Module): Variance-covariance wrong links and
                    561:   varian-covariance of ej. is needed (Saito).
                    562: 
                    563:   Revision 1.115  2006/02/27 12:17:45  brouard
                    564:   (Module): One freematrix added in mlikeli! 0.98c
                    565: 
                    566:   Revision 1.114  2006/02/26 12:57:58  brouard
                    567:   (Module): Some improvements in processing parameter
                    568:   filename with strsep.
                    569: 
                    570:   Revision 1.113  2006/02/24 14:20:24  brouard
                    571:   (Module): Memory leaks checks with valgrind and:
                    572:   datafile was not closed, some imatrix were not freed and on matrix
                    573:   allocation too.
                    574: 
                    575:   Revision 1.112  2006/01/30 09:55:26  brouard
                    576:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    577: 
                    578:   Revision 1.111  2006/01/25 20:38:18  brouard
                    579:   (Module): Lots of cleaning and bugs added (Gompertz)
                    580:   (Module): Comments can be added in data file. Missing date values
                    581:   can be a simple dot '.'.
                    582: 
                    583:   Revision 1.110  2006/01/25 00:51:50  brouard
                    584:   (Module): Lots of cleaning and bugs added (Gompertz)
                    585: 
                    586:   Revision 1.109  2006/01/24 19:37:15  brouard
                    587:   (Module): Comments (lines starting with a #) are allowed in data.
                    588: 
                    589:   Revision 1.108  2006/01/19 18:05:42  lievre
                    590:   Gnuplot problem appeared...
                    591:   To be fixed
                    592: 
                    593:   Revision 1.107  2006/01/19 16:20:37  brouard
                    594:   Test existence of gnuplot in imach path
                    595: 
                    596:   Revision 1.106  2006/01/19 13:24:36  brouard
                    597:   Some cleaning and links added in html output
                    598: 
                    599:   Revision 1.105  2006/01/05 20:23:19  lievre
                    600:   *** empty log message ***
                    601: 
                    602:   Revision 1.104  2005/09/30 16:11:43  lievre
                    603:   (Module): sump fixed, loop imx fixed, and simplifications.
                    604:   (Module): If the status is missing at the last wave but we know
                    605:   that the person is alive, then we can code his/her status as -2
                    606:   (instead of missing=-1 in earlier versions) and his/her
                    607:   contributions to the likelihood is 1 - Prob of dying from last
                    608:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    609:   the healthy state at last known wave). Version is 0.98
                    610: 
                    611:   Revision 1.103  2005/09/30 15:54:49  lievre
                    612:   (Module): sump fixed, loop imx fixed, and simplifications.
                    613: 
                    614:   Revision 1.102  2004/09/15 17:31:30  brouard
                    615:   Add the possibility to read data file including tab characters.
                    616: 
                    617:   Revision 1.101  2004/09/15 10:38:38  brouard
                    618:   Fix on curr_time
                    619: 
                    620:   Revision 1.100  2004/07/12 18:29:06  brouard
                    621:   Add version for Mac OS X. Just define UNIX in Makefile
                    622: 
                    623:   Revision 1.99  2004/06/05 08:57:40  brouard
                    624:   *** empty log message ***
                    625: 
                    626:   Revision 1.98  2004/05/16 15:05:56  brouard
                    627:   New version 0.97 . First attempt to estimate force of mortality
                    628:   directly from the data i.e. without the need of knowing the health
                    629:   state at each age, but using a Gompertz model: log u =a + b*age .
                    630:   This is the basic analysis of mortality and should be done before any
                    631:   other analysis, in order to test if the mortality estimated from the
                    632:   cross-longitudinal survey is different from the mortality estimated
                    633:   from other sources like vital statistic data.
                    634: 
                    635:   The same imach parameter file can be used but the option for mle should be -3.
                    636: 
1.133     brouard   637:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   638:   former routines in order to include the new code within the former code.
                    639: 
                    640:   The output is very simple: only an estimate of the intercept and of
                    641:   the slope with 95% confident intervals.
                    642: 
                    643:   Current limitations:
                    644:   A) Even if you enter covariates, i.e. with the
                    645:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    646:   B) There is no computation of Life Expectancy nor Life Table.
                    647: 
                    648:   Revision 1.97  2004/02/20 13:25:42  lievre
                    649:   Version 0.96d. Population forecasting command line is (temporarily)
                    650:   suppressed.
                    651: 
                    652:   Revision 1.96  2003/07/15 15:38:55  brouard
                    653:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    654:   rewritten within the same printf. Workaround: many printfs.
                    655: 
                    656:   Revision 1.95  2003/07/08 07:54:34  brouard
                    657:   * imach.c (Repository):
                    658:   (Repository): Using imachwizard code to output a more meaningful covariance
                    659:   matrix (cov(a12,c31) instead of numbers.
                    660: 
                    661:   Revision 1.94  2003/06/27 13:00:02  brouard
                    662:   Just cleaning
                    663: 
                    664:   Revision 1.93  2003/06/25 16:33:55  brouard
                    665:   (Module): On windows (cygwin) function asctime_r doesn't
                    666:   exist so I changed back to asctime which exists.
                    667:   (Module): Version 0.96b
                    668: 
                    669:   Revision 1.92  2003/06/25 16:30:45  brouard
                    670:   (Module): On windows (cygwin) function asctime_r doesn't
                    671:   exist so I changed back to asctime which exists.
                    672: 
                    673:   Revision 1.91  2003/06/25 15:30:29  brouard
                    674:   * imach.c (Repository): Duplicated warning errors corrected.
                    675:   (Repository): Elapsed time after each iteration is now output. It
                    676:   helps to forecast when convergence will be reached. Elapsed time
                    677:   is stamped in powell.  We created a new html file for the graphs
                    678:   concerning matrix of covariance. It has extension -cov.htm.
                    679: 
                    680:   Revision 1.90  2003/06/24 12:34:15  brouard
                    681:   (Module): Some bugs corrected for windows. Also, when
                    682:   mle=-1 a template is output in file "or"mypar.txt with the design
                    683:   of the covariance matrix to be input.
                    684: 
                    685:   Revision 1.89  2003/06/24 12:30:52  brouard
                    686:   (Module): Some bugs corrected for windows. Also, when
                    687:   mle=-1 a template is output in file "or"mypar.txt with the design
                    688:   of the covariance matrix to be input.
                    689: 
                    690:   Revision 1.88  2003/06/23 17:54:56  brouard
                    691:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    692: 
                    693:   Revision 1.87  2003/06/18 12:26:01  brouard
                    694:   Version 0.96
                    695: 
                    696:   Revision 1.86  2003/06/17 20:04:08  brouard
                    697:   (Module): Change position of html and gnuplot routines and added
                    698:   routine fileappend.
                    699: 
                    700:   Revision 1.85  2003/06/17 13:12:43  brouard
                    701:   * imach.c (Repository): Check when date of death was earlier that
                    702:   current date of interview. It may happen when the death was just
                    703:   prior to the death. In this case, dh was negative and likelihood
                    704:   was wrong (infinity). We still send an "Error" but patch by
                    705:   assuming that the date of death was just one stepm after the
                    706:   interview.
                    707:   (Repository): Because some people have very long ID (first column)
                    708:   we changed int to long in num[] and we added a new lvector for
                    709:   memory allocation. But we also truncated to 8 characters (left
                    710:   truncation)
                    711:   (Repository): No more line truncation errors.
                    712: 
                    713:   Revision 1.84  2003/06/13 21:44:43  brouard
                    714:   * imach.c (Repository): Replace "freqsummary" at a correct
                    715:   place. It differs from routine "prevalence" which may be called
                    716:   many times. Probs is memory consuming and must be used with
                    717:   parcimony.
                    718:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    719: 
                    720:   Revision 1.83  2003/06/10 13:39:11  lievre
                    721:   *** empty log message ***
                    722: 
                    723:   Revision 1.82  2003/06/05 15:57:20  brouard
                    724:   Add log in  imach.c and  fullversion number is now printed.
                    725: 
                    726: */
                    727: /*
                    728:    Interpolated Markov Chain
                    729: 
                    730:   Short summary of the programme:
                    731:   
1.227     brouard   732:   This program computes Healthy Life Expectancies or State-specific
                    733:   (if states aren't health statuses) Expectancies from
                    734:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    735: 
                    736:   -1- a first survey ("cross") where individuals from different ages
                    737:   are interviewed on their health status or degree of disability (in
                    738:   the case of a health survey which is our main interest)
                    739: 
                    740:   -2- at least a second wave of interviews ("longitudinal") which
                    741:   measure each change (if any) in individual health status.  Health
                    742:   expectancies are computed from the time spent in each health state
                    743:   according to a model. More health states you consider, more time is
                    744:   necessary to reach the Maximum Likelihood of the parameters involved
                    745:   in the model.  The simplest model is the multinomial logistic model
                    746:   where pij is the probability to be observed in state j at the second
                    747:   wave conditional to be observed in state i at the first
                    748:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    749:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    750:   have a more complex model than "constant and age", you should modify
                    751:   the program where the markup *Covariates have to be included here
                    752:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   753:   convergence.
                    754: 
                    755:   The advantage of this computer programme, compared to a simple
                    756:   multinomial logistic model, is clear when the delay between waves is not
                    757:   identical for each individual. Also, if a individual missed an
                    758:   intermediate interview, the information is lost, but taken into
                    759:   account using an interpolation or extrapolation.  
                    760: 
                    761:   hPijx is the probability to be observed in state i at age x+h
                    762:   conditional to the observed state i at age x. The delay 'h' can be
                    763:   split into an exact number (nh*stepm) of unobserved intermediate
                    764:   states. This elementary transition (by month, quarter,
                    765:   semester or year) is modelled as a multinomial logistic.  The hPx
                    766:   matrix is simply the matrix product of nh*stepm elementary matrices
                    767:   and the contribution of each individual to the likelihood is simply
                    768:   hPijx.
                    769: 
                    770:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   771:   of the life expectancies. It also computes the period (stable) prevalence.
                    772: 
                    773: Back prevalence and projections:
1.227     brouard   774: 
                    775:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    776:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    777:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    778:    mobilavproj)
                    779: 
                    780:     Computes the back prevalence limit for any combination of
                    781:     covariate values k at any age between ageminpar and agemaxpar and
                    782:     returns it in **bprlim. In the loops,
                    783: 
                    784:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    785:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    786: 
                    787:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   788:    Computes for any combination of covariates k and any age between bage and fage 
                    789:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    790:                        oldm=oldms;savm=savms;
1.227     brouard   791: 
                    792:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   793:      Computes the transition matrix starting at age 'age' over
                    794:      'nhstepm*hstepm*stepm' months (i.e. until
                    795:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   796:      nhstepm*hstepm matrices. 
                    797: 
                    798:      Returns p3mat[i][j][h] after calling
                    799:      p3mat[i][j][h]=matprod2(newm,
                    800:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    801:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    802:      oldm);
1.226     brouard   803: 
                    804: Important routines
                    805: 
                    806: - func (or funcone), computes logit (pij) distinguishing
                    807:   o fixed variables (single or product dummies or quantitative);
                    808:   o varying variables by:
                    809:    (1) wave (single, product dummies, quantitative), 
                    810:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    811:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    812:        % varying dummy (not done) or quantitative (not done);
                    813: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    814:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    815: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    816:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    817:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   818: 
1.226     brouard   819: 
                    820:   
1.133     brouard   821:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    822:            Institut national d'études démographiques, Paris.
1.126     brouard   823:   This software have been partly granted by Euro-REVES, a concerted action
                    824:   from the European Union.
                    825:   It is copyrighted identically to a GNU software product, ie programme and
                    826:   software can be distributed freely for non commercial use. Latest version
                    827:   can be accessed at http://euroreves.ined.fr/imach .
                    828: 
                    829:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    830:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    831:   
                    832:   **********************************************************************/
                    833: /*
                    834:   main
                    835:   read parameterfile
                    836:   read datafile
                    837:   concatwav
                    838:   freqsummary
                    839:   if (mle >= 1)
                    840:     mlikeli
                    841:   print results files
                    842:   if mle==1 
                    843:      computes hessian
                    844:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    845:       begin-prev-date,...
                    846:   open gnuplot file
                    847:   open html file
1.145     brouard   848:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    849:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    850:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    851:     freexexit2 possible for memory heap.
                    852: 
                    853:   h Pij x                         | pij_nom  ficrestpij
                    854:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    855:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    856:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    857: 
                    858:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    859:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    860:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    861:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    862:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    863: 
1.126     brouard   864:   forecasting if prevfcast==1 prevforecast call prevalence()
                    865:   health expectancies
                    866:   Variance-covariance of DFLE
                    867:   prevalence()
                    868:    movingaverage()
                    869:   varevsij() 
                    870:   if popbased==1 varevsij(,popbased)
                    871:   total life expectancies
                    872:   Variance of period (stable) prevalence
                    873:  end
                    874: */
                    875: 
1.187     brouard   876: /* #define DEBUG */
                    877: /* #define DEBUGBRENT */
1.203     brouard   878: /* #define DEBUGLINMIN */
                    879: /* #define DEBUGHESS */
                    880: #define DEBUGHESSIJ
1.224     brouard   881: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   882: #define POWELL /* Instead of NLOPT */
1.224     brouard   883: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   884: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    885: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   886: 
                    887: #include <math.h>
                    888: #include <stdio.h>
                    889: #include <stdlib.h>
                    890: #include <string.h>
1.226     brouard   891: #include <ctype.h>
1.159     brouard   892: 
                    893: #ifdef _WIN32
                    894: #include <io.h>
1.172     brouard   895: #include <windows.h>
                    896: #include <tchar.h>
1.159     brouard   897: #else
1.126     brouard   898: #include <unistd.h>
1.159     brouard   899: #endif
1.126     brouard   900: 
                    901: #include <limits.h>
                    902: #include <sys/types.h>
1.171     brouard   903: 
                    904: #if defined(__GNUC__)
                    905: #include <sys/utsname.h> /* Doesn't work on Windows */
                    906: #endif
                    907: 
1.126     brouard   908: #include <sys/stat.h>
                    909: #include <errno.h>
1.159     brouard   910: /* extern int errno; */
1.126     brouard   911: 
1.157     brouard   912: /* #ifdef LINUX */
                    913: /* #include <time.h> */
                    914: /* #include "timeval.h" */
                    915: /* #else */
                    916: /* #include <sys/time.h> */
                    917: /* #endif */
                    918: 
1.126     brouard   919: #include <time.h>
                    920: 
1.136     brouard   921: #ifdef GSL
                    922: #include <gsl/gsl_errno.h>
                    923: #include <gsl/gsl_multimin.h>
                    924: #endif
                    925: 
1.167     brouard   926: 
1.162     brouard   927: #ifdef NLOPT
                    928: #include <nlopt.h>
                    929: typedef struct {
                    930:   double (* function)(double [] );
                    931: } myfunc_data ;
                    932: #endif
                    933: 
1.126     brouard   934: /* #include <libintl.h> */
                    935: /* #define _(String) gettext (String) */
                    936: 
1.251     brouard   937: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   938: 
                    939: #define GNUPLOTPROGRAM "gnuplot"
                    940: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    941: #define FILENAMELENGTH 132
                    942: 
                    943: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    944: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    945: 
1.144     brouard   946: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    947: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   948: 
                    949: #define NINTERVMAX 8
1.144     brouard   950: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    951: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    952: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   953: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   954: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    955: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   956: #define MAXN 20000
1.144     brouard   957: #define YEARM 12. /**< Number of months per year */
1.218     brouard   958: /* #define AGESUP 130 */
                    959: #define AGESUP 150
                    960: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   961: #define AGEBASE 40
1.194     brouard   962: #define AGEOVERFLOW 1.e20
1.164     brouard   963: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   964: #ifdef _WIN32
                    965: #define DIRSEPARATOR '\\'
                    966: #define CHARSEPARATOR "\\"
                    967: #define ODIRSEPARATOR '/'
                    968: #else
1.126     brouard   969: #define DIRSEPARATOR '/'
                    970: #define CHARSEPARATOR "/"
                    971: #define ODIRSEPARATOR '\\'
                    972: #endif
                    973: 
1.258   ! brouard   974: /* $Id: imach.c,v 1.257 2017/03/29 16:53:30 brouard Exp $ */
1.126     brouard   975: /* $State: Exp $ */
1.196     brouard   976: #include "version.h"
                    977: char version[]=__IMACH_VERSION__;
1.224     brouard   978: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.258   ! brouard   979: char fullversion[]="$Revision: 1.257 $ $Date: 2017/03/29 16:53:30 $"; 
1.126     brouard   980: char strstart[80];
                    981: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   982: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   983: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   984: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    985: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    986: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   987: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    988: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard   989: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                    990: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                    991: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard   992: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                    993: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard   994: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard   995: int nsd=0; /**< Total number of single dummy variables (output) */
                    996: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard   997: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard   998: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard   999: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1000: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1001: int cptcov=0; /* Working variable */
1.218     brouard  1002: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1003: int npar=NPARMAX;
                   1004: int nlstate=2; /* Number of live states */
                   1005: int ndeath=1; /* Number of dead states */
1.130     brouard  1006: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1007: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1008: int popbased=0;
                   1009: 
                   1010: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1011: int maxwav=0; /* Maxim number of waves */
                   1012: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1013: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1014: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1015:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1016: int mle=1, weightopt=0;
1.126     brouard  1017: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1018: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1019: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1020:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1021: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1022: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1023: 
1.130     brouard  1024: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1025: double **matprod2(); /* test */
1.126     brouard  1026: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1027: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1028: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1029: 
1.136     brouard  1030: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1031: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1032: FILE *ficlog, *ficrespow;
1.130     brouard  1033: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1034: double fretone; /* Only one call to likelihood */
1.130     brouard  1035: long ipmx=0; /* Number of contributions */
1.126     brouard  1036: double sw; /* Sum of weights */
                   1037: char filerespow[FILENAMELENGTH];
                   1038: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1039: FILE *ficresilk;
                   1040: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1041: FILE *ficresprobmorprev;
                   1042: FILE *fichtm, *fichtmcov; /* Html File */
                   1043: FILE *ficreseij;
                   1044: char filerese[FILENAMELENGTH];
                   1045: FILE *ficresstdeij;
                   1046: char fileresstde[FILENAMELENGTH];
                   1047: FILE *ficrescveij;
                   1048: char filerescve[FILENAMELENGTH];
                   1049: FILE  *ficresvij;
                   1050: char fileresv[FILENAMELENGTH];
                   1051: FILE  *ficresvpl;
                   1052: char fileresvpl[FILENAMELENGTH];
                   1053: char title[MAXLINE];
1.234     brouard  1054: char model[MAXLINE]; /**< The model line */
1.217     brouard  1055: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1056: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1057: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1058: char command[FILENAMELENGTH];
                   1059: int  outcmd=0;
                   1060: 
1.217     brouard  1061: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1062: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1063: char filelog[FILENAMELENGTH]; /* Log file */
                   1064: char filerest[FILENAMELENGTH];
                   1065: char fileregp[FILENAMELENGTH];
                   1066: char popfile[FILENAMELENGTH];
                   1067: 
                   1068: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1069: 
1.157     brouard  1070: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1071: /* struct timezone tzp; */
                   1072: /* extern int gettimeofday(); */
                   1073: struct tm tml, *gmtime(), *localtime();
                   1074: 
                   1075: extern time_t time();
                   1076: 
                   1077: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1078: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1079: struct tm tm;
                   1080: 
1.126     brouard  1081: char strcurr[80], strfor[80];
                   1082: 
                   1083: char *endptr;
                   1084: long lval;
                   1085: double dval;
                   1086: 
                   1087: #define NR_END 1
                   1088: #define FREE_ARG char*
                   1089: #define FTOL 1.0e-10
                   1090: 
                   1091: #define NRANSI 
1.240     brouard  1092: #define ITMAX 200
                   1093: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1094: 
                   1095: #define TOL 2.0e-4 
                   1096: 
                   1097: #define CGOLD 0.3819660 
                   1098: #define ZEPS 1.0e-10 
                   1099: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1100: 
                   1101: #define GOLD 1.618034 
                   1102: #define GLIMIT 100.0 
                   1103: #define TINY 1.0e-20 
                   1104: 
                   1105: static double maxarg1,maxarg2;
                   1106: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1107: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1108:   
                   1109: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1110: #define rint(a) floor(a+0.5)
1.166     brouard  1111: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1112: #define mytinydouble 1.0e-16
1.166     brouard  1113: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1114: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1115: /* static double dsqrarg; */
                   1116: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1117: static double sqrarg;
                   1118: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1119: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1120: int agegomp= AGEGOMP;
                   1121: 
                   1122: int imx; 
                   1123: int stepm=1;
                   1124: /* Stepm, step in month: minimum step interpolation*/
                   1125: 
                   1126: int estepm;
                   1127: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1128: 
                   1129: int m,nb;
                   1130: long *num;
1.197     brouard  1131: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1132: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1133:                   covariate for which somebody answered excluding 
                   1134:                   undefined. Usually 2: 0 and 1. */
                   1135: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1136:                             covariate for which somebody answered including 
                   1137:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1138: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1139: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1140: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1141: double *ageexmed,*agecens;
                   1142: double dateintmean=0;
                   1143: 
                   1144: double *weight;
                   1145: int **s; /* Status */
1.141     brouard  1146: double *agedc;
1.145     brouard  1147: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1148:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1149:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1150: double **coqvar; /* Fixed quantitative covariate iqv */
                   1151: double ***cotvar; /* Time varying covariate itv */
                   1152: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1153: double  idx; 
                   1154: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1155: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1156: /*k          1  2   3   4     5    6    7     8    9 */
                   1157: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1158: /* Tndvar[k]    1   2   3               4          5 */
                   1159: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1160: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1161: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1162: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1163: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1164: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1165: /* Tprod[i]=k           4               7            */
                   1166: /* Tage[i]=k                  5               8      */
                   1167: /* */
                   1168: /* Type                    */
                   1169: /* V         1  2  3  4  5 */
                   1170: /*           F  F  V  V  V */
                   1171: /*           D  Q  D  D  Q */
                   1172: /*                         */
                   1173: int *TvarsD;
                   1174: int *TvarsDind;
                   1175: int *TvarsQ;
                   1176: int *TvarsQind;
                   1177: 
1.235     brouard  1178: #define MAXRESULTLINES 10
                   1179: int nresult=0;
1.258   ! brouard  1180: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1181: int TKresult[MAXRESULTLINES];
1.237     brouard  1182: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1183: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1184: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1185: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1186: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1187: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1188: 
1.234     brouard  1189: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1190: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1191: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1192: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1193: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1194: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1195: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1196: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1197: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1198: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1199: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1200: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1201: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1202: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1203: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1204: 
1.230     brouard  1205: int *Tvarsel; /**< Selected covariates for output */
                   1206: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1207: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1208: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1209: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1210: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1211: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1212: int *Tage;
1.227     brouard  1213: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1214: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1215: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1216: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1217: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1218: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1219: int **Tvard;
                   1220: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1221: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1222: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1223:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1224:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1225: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1226: double *lsurv, *lpop, *tpop;
                   1227: 
1.231     brouard  1228: #define FD 1; /* Fixed dummy covariate */
                   1229: #define FQ 2; /* Fixed quantitative covariate */
                   1230: #define FP 3; /* Fixed product covariate */
                   1231: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1232: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1233: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1234: #define VD 10; /* Varying dummy covariate */
                   1235: #define VQ 11; /* Varying quantitative covariate */
                   1236: #define VP 12; /* Varying product covariate */
                   1237: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1238: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1239: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1240: #define APFD 16; /* Age product * fixed dummy covariate */
                   1241: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1242: #define APVD 18; /* Age product * varying dummy covariate */
                   1243: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1244: 
                   1245: #define FTYPE 1; /* Fixed covariate */
                   1246: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1247: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1248: 
                   1249: struct kmodel{
                   1250:        int maintype; /* main type */
                   1251:        int subtype; /* subtype */
                   1252: };
                   1253: struct kmodel modell[NCOVMAX];
                   1254: 
1.143     brouard  1255: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1256: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1257: 
                   1258: /**************** split *************************/
                   1259: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1260: {
                   1261:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1262:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1263:   */ 
                   1264:   char *ss;                            /* pointer */
1.186     brouard  1265:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1266: 
                   1267:   l1 = strlen(path );                  /* length of path */
                   1268:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1269:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1270:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1271:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1272:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1273:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1274:     /* get current working directory */
                   1275:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1276: #ifdef WIN32
                   1277:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1278: #else
                   1279:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1280: #endif
1.126     brouard  1281:       return( GLOCK_ERROR_GETCWD );
                   1282:     }
                   1283:     /* got dirc from getcwd*/
                   1284:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1285:   } else {                             /* strip directory from path */
1.126     brouard  1286:     ss++;                              /* after this, the filename */
                   1287:     l2 = strlen( ss );                 /* length of filename */
                   1288:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1289:     strcpy( name, ss );                /* save file name */
                   1290:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1291:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1292:     printf(" DIRC2 = %s \n",dirc);
                   1293:   }
                   1294:   /* We add a separator at the end of dirc if not exists */
                   1295:   l1 = strlen( dirc );                 /* length of directory */
                   1296:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1297:     dirc[l1] =  DIRSEPARATOR;
                   1298:     dirc[l1+1] = 0; 
                   1299:     printf(" DIRC3 = %s \n",dirc);
                   1300:   }
                   1301:   ss = strrchr( name, '.' );           /* find last / */
                   1302:   if (ss >0){
                   1303:     ss++;
                   1304:     strcpy(ext,ss);                    /* save extension */
                   1305:     l1= strlen( name);
                   1306:     l2= strlen(ss)+1;
                   1307:     strncpy( finame, name, l1-l2);
                   1308:     finame[l1-l2]= 0;
                   1309:   }
                   1310: 
                   1311:   return( 0 );                         /* we're done */
                   1312: }
                   1313: 
                   1314: 
                   1315: /******************************************/
                   1316: 
                   1317: void replace_back_to_slash(char *s, char*t)
                   1318: {
                   1319:   int i;
                   1320:   int lg=0;
                   1321:   i=0;
                   1322:   lg=strlen(t);
                   1323:   for(i=0; i<= lg; i++) {
                   1324:     (s[i] = t[i]);
                   1325:     if (t[i]== '\\') s[i]='/';
                   1326:   }
                   1327: }
                   1328: 
1.132     brouard  1329: char *trimbb(char *out, char *in)
1.137     brouard  1330: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1331:   char *s;
                   1332:   s=out;
                   1333:   while (*in != '\0'){
1.137     brouard  1334:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1335:       in++;
                   1336:     }
                   1337:     *out++ = *in++;
                   1338:   }
                   1339:   *out='\0';
                   1340:   return s;
                   1341: }
                   1342: 
1.187     brouard  1343: /* char *substrchaine(char *out, char *in, char *chain) */
                   1344: /* { */
                   1345: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1346: /*   char *s, *t; */
                   1347: /*   t=in;s=out; */
                   1348: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1349: /*     *out++ = *in++; */
                   1350: /*   } */
                   1351: 
                   1352: /*   /\* *in matches *chain *\/ */
                   1353: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1354: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1355: /*   } */
                   1356: /*   in--; chain--; */
                   1357: /*   while ( (*in != '\0')){ */
                   1358: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1359: /*     *out++ = *in++; */
                   1360: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1361: /*   } */
                   1362: /*   *out='\0'; */
                   1363: /*   out=s; */
                   1364: /*   return out; */
                   1365: /* } */
                   1366: char *substrchaine(char *out, char *in, char *chain)
                   1367: {
                   1368:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1369:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1370: 
                   1371:   char *strloc;
                   1372: 
                   1373:   strcpy (out, in); 
                   1374:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1375:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1376:   if(strloc != NULL){ 
                   1377:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1378:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1379:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1380:   }
                   1381:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1382:   return out;
                   1383: }
                   1384: 
                   1385: 
1.145     brouard  1386: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1387: {
1.187     brouard  1388:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1389:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1390:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1391:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1392:   */
1.160     brouard  1393:   char *s, *t;
1.145     brouard  1394:   t=in;s=in;
                   1395:   while ((*in != occ) && (*in != '\0')){
                   1396:     *alocc++ = *in++;
                   1397:   }
                   1398:   if( *in == occ){
                   1399:     *(alocc)='\0';
                   1400:     s=++in;
                   1401:   }
                   1402:  
                   1403:   if (s == t) {/* occ not found */
                   1404:     *(alocc-(in-s))='\0';
                   1405:     in=s;
                   1406:   }
                   1407:   while ( *in != '\0'){
                   1408:     *blocc++ = *in++;
                   1409:   }
                   1410: 
                   1411:   *blocc='\0';
                   1412:   return t;
                   1413: }
1.137     brouard  1414: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1415: {
1.187     brouard  1416:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1417:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1418:      gives blocc="abcdef2ghi" and alocc="j".
                   1419:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1420:   */
                   1421:   char *s, *t;
                   1422:   t=in;s=in;
                   1423:   while (*in != '\0'){
                   1424:     while( *in == occ){
                   1425:       *blocc++ = *in++;
                   1426:       s=in;
                   1427:     }
                   1428:     *blocc++ = *in++;
                   1429:   }
                   1430:   if (s == t) /* occ not found */
                   1431:     *(blocc-(in-s))='\0';
                   1432:   else
                   1433:     *(blocc-(in-s)-1)='\0';
                   1434:   in=s;
                   1435:   while ( *in != '\0'){
                   1436:     *alocc++ = *in++;
                   1437:   }
                   1438: 
                   1439:   *alocc='\0';
                   1440:   return s;
                   1441: }
                   1442: 
1.126     brouard  1443: int nbocc(char *s, char occ)
                   1444: {
                   1445:   int i,j=0;
                   1446:   int lg=20;
                   1447:   i=0;
                   1448:   lg=strlen(s);
                   1449:   for(i=0; i<= lg; i++) {
1.234     brouard  1450:     if  (s[i] == occ ) j++;
1.126     brouard  1451:   }
                   1452:   return j;
                   1453: }
                   1454: 
1.137     brouard  1455: /* void cutv(char *u,char *v, char*t, char occ) */
                   1456: /* { */
                   1457: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1458: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1459: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1460: /*   int i,lg,j,p=0; */
                   1461: /*   i=0; */
                   1462: /*   lg=strlen(t); */
                   1463: /*   for(j=0; j<=lg-1; j++) { */
                   1464: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1465: /*   } */
1.126     brouard  1466: 
1.137     brouard  1467: /*   for(j=0; j<p; j++) { */
                   1468: /*     (u[j] = t[j]); */
                   1469: /*   } */
                   1470: /*      u[p]='\0'; */
1.126     brouard  1471: 
1.137     brouard  1472: /*    for(j=0; j<= lg; j++) { */
                   1473: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1474: /*   } */
                   1475: /* } */
1.126     brouard  1476: 
1.160     brouard  1477: #ifdef _WIN32
                   1478: char * strsep(char **pp, const char *delim)
                   1479: {
                   1480:   char *p, *q;
                   1481:          
                   1482:   if ((p = *pp) == NULL)
                   1483:     return 0;
                   1484:   if ((q = strpbrk (p, delim)) != NULL)
                   1485:   {
                   1486:     *pp = q + 1;
                   1487:     *q = '\0';
                   1488:   }
                   1489:   else
                   1490:     *pp = 0;
                   1491:   return p;
                   1492: }
                   1493: #endif
                   1494: 
1.126     brouard  1495: /********************** nrerror ********************/
                   1496: 
                   1497: void nrerror(char error_text[])
                   1498: {
                   1499:   fprintf(stderr,"ERREUR ...\n");
                   1500:   fprintf(stderr,"%s\n",error_text);
                   1501:   exit(EXIT_FAILURE);
                   1502: }
                   1503: /*********************** vector *******************/
                   1504: double *vector(int nl, int nh)
                   1505: {
                   1506:   double *v;
                   1507:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1508:   if (!v) nrerror("allocation failure in vector");
                   1509:   return v-nl+NR_END;
                   1510: }
                   1511: 
                   1512: /************************ free vector ******************/
                   1513: void free_vector(double*v, int nl, int nh)
                   1514: {
                   1515:   free((FREE_ARG)(v+nl-NR_END));
                   1516: }
                   1517: 
                   1518: /************************ivector *******************************/
                   1519: int *ivector(long nl,long nh)
                   1520: {
                   1521:   int *v;
                   1522:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1523:   if (!v) nrerror("allocation failure in ivector");
                   1524:   return v-nl+NR_END;
                   1525: }
                   1526: 
                   1527: /******************free ivector **************************/
                   1528: void free_ivector(int *v, long nl, long nh)
                   1529: {
                   1530:   free((FREE_ARG)(v+nl-NR_END));
                   1531: }
                   1532: 
                   1533: /************************lvector *******************************/
                   1534: long *lvector(long nl,long nh)
                   1535: {
                   1536:   long *v;
                   1537:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1538:   if (!v) nrerror("allocation failure in ivector");
                   1539:   return v-nl+NR_END;
                   1540: }
                   1541: 
                   1542: /******************free lvector **************************/
                   1543: void free_lvector(long *v, long nl, long nh)
                   1544: {
                   1545:   free((FREE_ARG)(v+nl-NR_END));
                   1546: }
                   1547: 
                   1548: /******************* imatrix *******************************/
                   1549: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1550:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1551: { 
                   1552:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1553:   int **m; 
                   1554:   
                   1555:   /* allocate pointers to rows */ 
                   1556:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1557:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1558:   m += NR_END; 
                   1559:   m -= nrl; 
                   1560:   
                   1561:   
                   1562:   /* allocate rows and set pointers to them */ 
                   1563:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1564:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1565:   m[nrl] += NR_END; 
                   1566:   m[nrl] -= ncl; 
                   1567:   
                   1568:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1569:   
                   1570:   /* return pointer to array of pointers to rows */ 
                   1571:   return m; 
                   1572: } 
                   1573: 
                   1574: /****************** free_imatrix *************************/
                   1575: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1576:       int **m;
                   1577:       long nch,ncl,nrh,nrl; 
                   1578:      /* free an int matrix allocated by imatrix() */ 
                   1579: { 
                   1580:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1581:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1582: } 
                   1583: 
                   1584: /******************* matrix *******************************/
                   1585: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1586: {
                   1587:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1588:   double **m;
                   1589: 
                   1590:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1591:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1592:   m += NR_END;
                   1593:   m -= nrl;
                   1594: 
                   1595:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1596:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1597:   m[nrl] += NR_END;
                   1598:   m[nrl] -= ncl;
                   1599: 
                   1600:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1601:   return m;
1.145     brouard  1602:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1603: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1604: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1605:    */
                   1606: }
                   1607: 
                   1608: /*************************free matrix ************************/
                   1609: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1610: {
                   1611:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1612:   free((FREE_ARG)(m+nrl-NR_END));
                   1613: }
                   1614: 
                   1615: /******************* ma3x *******************************/
                   1616: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1617: {
                   1618:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1619:   double ***m;
                   1620: 
                   1621:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1622:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1623:   m += NR_END;
                   1624:   m -= nrl;
                   1625: 
                   1626:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1627:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1628:   m[nrl] += NR_END;
                   1629:   m[nrl] -= ncl;
                   1630: 
                   1631:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1632: 
                   1633:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1634:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1635:   m[nrl][ncl] += NR_END;
                   1636:   m[nrl][ncl] -= nll;
                   1637:   for (j=ncl+1; j<=nch; j++) 
                   1638:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1639:   
                   1640:   for (i=nrl+1; i<=nrh; i++) {
                   1641:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1642:     for (j=ncl+1; j<=nch; j++) 
                   1643:       m[i][j]=m[i][j-1]+nlay;
                   1644:   }
                   1645:   return m; 
                   1646:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1647:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1648:   */
                   1649: }
                   1650: 
                   1651: /*************************free ma3x ************************/
                   1652: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1653: {
                   1654:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1655:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1656:   free((FREE_ARG)(m+nrl-NR_END));
                   1657: }
                   1658: 
                   1659: /*************** function subdirf ***********/
                   1660: char *subdirf(char fileres[])
                   1661: {
                   1662:   /* Caution optionfilefiname is hidden */
                   1663:   strcpy(tmpout,optionfilefiname);
                   1664:   strcat(tmpout,"/"); /* Add to the right */
                   1665:   strcat(tmpout,fileres);
                   1666:   return tmpout;
                   1667: }
                   1668: 
                   1669: /*************** function subdirf2 ***********/
                   1670: char *subdirf2(char fileres[], char *preop)
                   1671: {
                   1672:   
                   1673:   /* Caution optionfilefiname is hidden */
                   1674:   strcpy(tmpout,optionfilefiname);
                   1675:   strcat(tmpout,"/");
                   1676:   strcat(tmpout,preop);
                   1677:   strcat(tmpout,fileres);
                   1678:   return tmpout;
                   1679: }
                   1680: 
                   1681: /*************** function subdirf3 ***********/
                   1682: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1683: {
                   1684:   
                   1685:   /* Caution optionfilefiname is hidden */
                   1686:   strcpy(tmpout,optionfilefiname);
                   1687:   strcat(tmpout,"/");
                   1688:   strcat(tmpout,preop);
                   1689:   strcat(tmpout,preop2);
                   1690:   strcat(tmpout,fileres);
                   1691:   return tmpout;
                   1692: }
1.213     brouard  1693:  
                   1694: /*************** function subdirfext ***********/
                   1695: char *subdirfext(char fileres[], char *preop, char *postop)
                   1696: {
                   1697:   
                   1698:   strcpy(tmpout,preop);
                   1699:   strcat(tmpout,fileres);
                   1700:   strcat(tmpout,postop);
                   1701:   return tmpout;
                   1702: }
1.126     brouard  1703: 
1.213     brouard  1704: /*************** function subdirfext3 ***********/
                   1705: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1706: {
                   1707:   
                   1708:   /* Caution optionfilefiname is hidden */
                   1709:   strcpy(tmpout,optionfilefiname);
                   1710:   strcat(tmpout,"/");
                   1711:   strcat(tmpout,preop);
                   1712:   strcat(tmpout,fileres);
                   1713:   strcat(tmpout,postop);
                   1714:   return tmpout;
                   1715: }
                   1716:  
1.162     brouard  1717: char *asc_diff_time(long time_sec, char ascdiff[])
                   1718: {
                   1719:   long sec_left, days, hours, minutes;
                   1720:   days = (time_sec) / (60*60*24);
                   1721:   sec_left = (time_sec) % (60*60*24);
                   1722:   hours = (sec_left) / (60*60) ;
                   1723:   sec_left = (sec_left) %(60*60);
                   1724:   minutes = (sec_left) /60;
                   1725:   sec_left = (sec_left) % (60);
                   1726:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1727:   return ascdiff;
                   1728: }
                   1729: 
1.126     brouard  1730: /***************** f1dim *************************/
                   1731: extern int ncom; 
                   1732: extern double *pcom,*xicom;
                   1733: extern double (*nrfunc)(double []); 
                   1734:  
                   1735: double f1dim(double x) 
                   1736: { 
                   1737:   int j; 
                   1738:   double f;
                   1739:   double *xt; 
                   1740:  
                   1741:   xt=vector(1,ncom); 
                   1742:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1743:   f=(*nrfunc)(xt); 
                   1744:   free_vector(xt,1,ncom); 
                   1745:   return f; 
                   1746: } 
                   1747: 
                   1748: /*****************brent *************************/
                   1749: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1750: {
                   1751:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1752:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1753:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1754:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1755:    * returned function value. 
                   1756:   */
1.126     brouard  1757:   int iter; 
                   1758:   double a,b,d,etemp;
1.159     brouard  1759:   double fu=0,fv,fw,fx;
1.164     brouard  1760:   double ftemp=0.;
1.126     brouard  1761:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1762:   double e=0.0; 
                   1763:  
                   1764:   a=(ax < cx ? ax : cx); 
                   1765:   b=(ax > cx ? ax : cx); 
                   1766:   x=w=v=bx; 
                   1767:   fw=fv=fx=(*f)(x); 
                   1768:   for (iter=1;iter<=ITMAX;iter++) { 
                   1769:     xm=0.5*(a+b); 
                   1770:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1771:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1772:     printf(".");fflush(stdout);
                   1773:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1774: #ifdef DEBUGBRENT
1.126     brouard  1775:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1776:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1777:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1778: #endif
                   1779:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1780:       *xmin=x; 
                   1781:       return fx; 
                   1782:     } 
                   1783:     ftemp=fu;
                   1784:     if (fabs(e) > tol1) { 
                   1785:       r=(x-w)*(fx-fv); 
                   1786:       q=(x-v)*(fx-fw); 
                   1787:       p=(x-v)*q-(x-w)*r; 
                   1788:       q=2.0*(q-r); 
                   1789:       if (q > 0.0) p = -p; 
                   1790:       q=fabs(q); 
                   1791:       etemp=e; 
                   1792:       e=d; 
                   1793:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1794:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1795:       else { 
1.224     brouard  1796:                                d=p/q; 
                   1797:                                u=x+d; 
                   1798:                                if (u-a < tol2 || b-u < tol2) 
                   1799:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1800:       } 
                   1801:     } else { 
                   1802:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1803:     } 
                   1804:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1805:     fu=(*f)(u); 
                   1806:     if (fu <= fx) { 
                   1807:       if (u >= x) a=x; else b=x; 
                   1808:       SHFT(v,w,x,u) 
1.183     brouard  1809:       SHFT(fv,fw,fx,fu) 
                   1810:     } else { 
                   1811:       if (u < x) a=u; else b=u; 
                   1812:       if (fu <= fw || w == x) { 
1.224     brouard  1813:                                v=w; 
                   1814:                                w=u; 
                   1815:                                fv=fw; 
                   1816:                                fw=fu; 
1.183     brouard  1817:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1818:                                v=u; 
                   1819:                                fv=fu; 
1.183     brouard  1820:       } 
                   1821:     } 
1.126     brouard  1822:   } 
                   1823:   nrerror("Too many iterations in brent"); 
                   1824:   *xmin=x; 
                   1825:   return fx; 
                   1826: } 
                   1827: 
                   1828: /****************** mnbrak ***********************/
                   1829: 
                   1830: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1831:            double (*func)(double)) 
1.183     brouard  1832: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1833: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1834: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1835: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1836:    */
1.126     brouard  1837:   double ulim,u,r,q, dum;
                   1838:   double fu; 
1.187     brouard  1839: 
                   1840:   double scale=10.;
                   1841:   int iterscale=0;
                   1842: 
                   1843:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1844:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1845: 
                   1846: 
                   1847:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1848:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1849:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1850:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1851:   /* } */
                   1852: 
1.126     brouard  1853:   if (*fb > *fa) { 
                   1854:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1855:     SHFT(dum,*fb,*fa,dum) 
                   1856:   } 
1.126     brouard  1857:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1858:   *fc=(*func)(*cx); 
1.183     brouard  1859: #ifdef DEBUG
1.224     brouard  1860:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1861:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1862: #endif
1.224     brouard  1863:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1864:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1865:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1866:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1867:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1868:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1869:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1870:       fu=(*func)(u); 
1.163     brouard  1871: #ifdef DEBUG
                   1872:       /* f(x)=A(x-u)**2+f(u) */
                   1873:       double A, fparabu; 
                   1874:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1875:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1876:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1877:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1878:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1879:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1880:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1881:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1882: #endif 
1.184     brouard  1883: #ifdef MNBRAKORIGINAL
1.183     brouard  1884: #else
1.191     brouard  1885: /*       if (fu > *fc) { */
                   1886: /* #ifdef DEBUG */
                   1887: /*       printf("mnbrak4  fu > fc \n"); */
                   1888: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1889: /* #endif */
                   1890: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1891: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1892: /*     dum=u; /\* Shifting c and u *\/ */
                   1893: /*     u = *cx; */
                   1894: /*     *cx = dum; */
                   1895: /*     dum = fu; */
                   1896: /*     fu = *fc; */
                   1897: /*     *fc =dum; */
                   1898: /*       } else { /\* end *\/ */
                   1899: /* #ifdef DEBUG */
                   1900: /*       printf("mnbrak3  fu < fc \n"); */
                   1901: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1902: /* #endif */
                   1903: /*     dum=u; /\* Shifting c and u *\/ */
                   1904: /*     u = *cx; */
                   1905: /*     *cx = dum; */
                   1906: /*     dum = fu; */
                   1907: /*     fu = *fc; */
                   1908: /*     *fc =dum; */
                   1909: /*       } */
1.224     brouard  1910: #ifdef DEBUGMNBRAK
                   1911:                 double A, fparabu; 
                   1912:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1913:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1914:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1915:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1916: #endif
1.191     brouard  1917:       dum=u; /* Shifting c and u */
                   1918:       u = *cx;
                   1919:       *cx = dum;
                   1920:       dum = fu;
                   1921:       fu = *fc;
                   1922:       *fc =dum;
1.183     brouard  1923: #endif
1.162     brouard  1924:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1925: #ifdef DEBUG
1.224     brouard  1926:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1927:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1928: #endif
1.126     brouard  1929:       fu=(*func)(u); 
                   1930:       if (fu < *fc) { 
1.183     brouard  1931: #ifdef DEBUG
1.224     brouard  1932:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1933:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1934: #endif
                   1935:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1936:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1937: #ifdef DEBUG
                   1938:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1939: #endif
                   1940:       } 
1.162     brouard  1941:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1942: #ifdef DEBUG
1.224     brouard  1943:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1944:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1945: #endif
1.126     brouard  1946:       u=ulim; 
                   1947:       fu=(*func)(u); 
1.183     brouard  1948:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1949: #ifdef DEBUG
1.224     brouard  1950:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1951:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1952: #endif
1.126     brouard  1953:       u=(*cx)+GOLD*(*cx-*bx); 
                   1954:       fu=(*func)(u); 
1.224     brouard  1955: #ifdef DEBUG
                   1956:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1957:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1958: #endif
1.183     brouard  1959:     } /* end tests */
1.126     brouard  1960:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1961:     SHFT(*fa,*fb,*fc,fu) 
                   1962: #ifdef DEBUG
1.224     brouard  1963:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1964:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1965: #endif
                   1966:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1967: } 
                   1968: 
                   1969: /*************** linmin ************************/
1.162     brouard  1970: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1971: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1972: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1973: the value of func at the returned location p . This is actually all accomplished by calling the
                   1974: routines mnbrak and brent .*/
1.126     brouard  1975: int ncom; 
                   1976: double *pcom,*xicom;
                   1977: double (*nrfunc)(double []); 
                   1978:  
1.224     brouard  1979: #ifdef LINMINORIGINAL
1.126     brouard  1980: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1981: #else
                   1982: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1983: #endif
1.126     brouard  1984: { 
                   1985:   double brent(double ax, double bx, double cx, 
                   1986:               double (*f)(double), double tol, double *xmin); 
                   1987:   double f1dim(double x); 
                   1988:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   1989:              double *fc, double (*func)(double)); 
                   1990:   int j; 
                   1991:   double xx,xmin,bx,ax; 
                   1992:   double fx,fb,fa;
1.187     brouard  1993: 
1.203     brouard  1994: #ifdef LINMINORIGINAL
                   1995: #else
                   1996:   double scale=10., axs, xxs; /* Scale added for infinity */
                   1997: #endif
                   1998:   
1.126     brouard  1999:   ncom=n; 
                   2000:   pcom=vector(1,n); 
                   2001:   xicom=vector(1,n); 
                   2002:   nrfunc=func; 
                   2003:   for (j=1;j<=n;j++) { 
                   2004:     pcom[j]=p[j]; 
1.202     brouard  2005:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2006:   } 
1.187     brouard  2007: 
1.203     brouard  2008: #ifdef LINMINORIGINAL
                   2009:   xx=1.;
                   2010: #else
                   2011:   axs=0.0;
                   2012:   xxs=1.;
                   2013:   do{
                   2014:     xx= xxs;
                   2015: #endif
1.187     brouard  2016:     ax=0.;
                   2017:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2018:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2019:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2020:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2021:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2022:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2023:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2024: #ifdef LINMINORIGINAL
                   2025: #else
                   2026:     if (fx != fx){
1.224     brouard  2027:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2028:                        printf("|");
                   2029:                        fprintf(ficlog,"|");
1.203     brouard  2030: #ifdef DEBUGLINMIN
1.224     brouard  2031:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2032: #endif
                   2033:     }
1.224     brouard  2034:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2035: #endif
                   2036:   
1.191     brouard  2037: #ifdef DEBUGLINMIN
                   2038:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2039:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2040: #endif
1.224     brouard  2041: #ifdef LINMINORIGINAL
                   2042: #else
                   2043:        if(fb == fx){ /* Flat function in the direction */
                   2044:                xmin=xx;
                   2045:     *flat=1;
                   2046:        }else{
                   2047:     *flat=0;
                   2048: #endif
                   2049:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2050:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2051:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2052:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2053:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2054:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2055: #ifdef DEBUG
1.224     brouard  2056:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2057:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2058: #endif
                   2059: #ifdef LINMINORIGINAL
                   2060: #else
                   2061:                        }
1.126     brouard  2062: #endif
1.191     brouard  2063: #ifdef DEBUGLINMIN
                   2064:   printf("linmin end ");
1.202     brouard  2065:   fprintf(ficlog,"linmin end ");
1.191     brouard  2066: #endif
1.126     brouard  2067:   for (j=1;j<=n;j++) { 
1.203     brouard  2068: #ifdef LINMINORIGINAL
                   2069:     xi[j] *= xmin; 
                   2070: #else
                   2071: #ifdef DEBUGLINMIN
                   2072:     if(xxs <1.0)
                   2073:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2074: #endif
                   2075:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2076: #ifdef DEBUGLINMIN
                   2077:     if(xxs <1.0)
                   2078:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2079: #endif
                   2080: #endif
1.187     brouard  2081:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2082:   } 
1.191     brouard  2083: #ifdef DEBUGLINMIN
1.203     brouard  2084:   printf("\n");
1.191     brouard  2085:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2086:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2087:   for (j=1;j<=n;j++) { 
1.202     brouard  2088:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2089:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2090:     if(j % ncovmodel == 0){
1.191     brouard  2091:       printf("\n");
1.202     brouard  2092:       fprintf(ficlog,"\n");
                   2093:     }
1.191     brouard  2094:   }
1.203     brouard  2095: #else
1.191     brouard  2096: #endif
1.126     brouard  2097:   free_vector(xicom,1,n); 
                   2098:   free_vector(pcom,1,n); 
                   2099: } 
                   2100: 
                   2101: 
                   2102: /*************** powell ************************/
1.162     brouard  2103: /*
                   2104: Minimization of a function func of n variables. Input consists of an initial starting point
                   2105: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2106: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2107: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2108: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2109: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2110:  */
1.224     brouard  2111: #ifdef LINMINORIGINAL
                   2112: #else
                   2113:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2114:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2115: #endif
1.126     brouard  2116: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2117:            double (*func)(double [])) 
                   2118: { 
1.224     brouard  2119: #ifdef LINMINORIGINAL
                   2120:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2121:              double (*func)(double [])); 
1.224     brouard  2122: #else 
1.241     brouard  2123:  void linmin(double p[], double xi[], int n, double *fret,
                   2124:             double (*func)(double []),int *flat); 
1.224     brouard  2125: #endif
1.239     brouard  2126:  int i,ibig,j,jk,k; 
1.126     brouard  2127:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2128:   double directest;
1.126     brouard  2129:   double fp,fptt;
                   2130:   double *xits;
                   2131:   int niterf, itmp;
1.224     brouard  2132: #ifdef LINMINORIGINAL
                   2133: #else
                   2134: 
                   2135:   flatdir=ivector(1,n); 
                   2136:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2137: #endif
1.126     brouard  2138: 
                   2139:   pt=vector(1,n); 
                   2140:   ptt=vector(1,n); 
                   2141:   xit=vector(1,n); 
                   2142:   xits=vector(1,n); 
                   2143:   *fret=(*func)(p); 
                   2144:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2145:   rcurr_time = time(NULL);  
1.126     brouard  2146:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2147:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2148:     ibig=0; 
                   2149:     del=0.0; 
1.157     brouard  2150:     rlast_time=rcurr_time;
                   2151:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2152:     rcurr_time = time(NULL);  
                   2153:     curr_time = *localtime(&rcurr_time);
                   2154:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2155:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2156: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2157:     for (i=1;i<=n;i++) {
1.126     brouard  2158:       fprintf(ficrespow," %.12lf", p[i]);
                   2159:     }
1.239     brouard  2160:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2161:     printf("\n#model=  1      +     age ");
                   2162:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2163:     if(nagesqr==1){
1.241     brouard  2164:        printf("  + age*age  ");
                   2165:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2166:     }
                   2167:     for(j=1;j <=ncovmodel-2;j++){
                   2168:       if(Typevar[j]==0) {
                   2169:        printf("  +      V%d  ",Tvar[j]);
                   2170:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2171:       }else if(Typevar[j]==1) {
                   2172:        printf("  +    V%d*age ",Tvar[j]);
                   2173:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2174:       }else if(Typevar[j]==2) {
                   2175:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2176:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2177:       }
                   2178:     }
1.126     brouard  2179:     printf("\n");
1.239     brouard  2180: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2181: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2182:     fprintf(ficlog,"\n");
1.239     brouard  2183:     for(i=1,jk=1; i <=nlstate; i++){
                   2184:       for(k=1; k <=(nlstate+ndeath); k++){
                   2185:        if (k != i) {
                   2186:          printf("%d%d ",i,k);
                   2187:          fprintf(ficlog,"%d%d ",i,k);
                   2188:          for(j=1; j <=ncovmodel; j++){
                   2189:            printf("%12.7f ",p[jk]);
                   2190:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2191:            jk++; 
                   2192:          }
                   2193:          printf("\n");
                   2194:          fprintf(ficlog,"\n");
                   2195:        }
                   2196:       }
                   2197:     }
1.241     brouard  2198:     if(*iter <=3 && *iter >1){
1.157     brouard  2199:       tml = *localtime(&rcurr_time);
                   2200:       strcpy(strcurr,asctime(&tml));
                   2201:       rforecast_time=rcurr_time; 
1.126     brouard  2202:       itmp = strlen(strcurr);
                   2203:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2204:        strcurr[itmp-1]='\0';
1.162     brouard  2205:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2206:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2207:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2208:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2209:        forecast_time = *localtime(&rforecast_time);
                   2210:        strcpy(strfor,asctime(&forecast_time));
                   2211:        itmp = strlen(strfor);
                   2212:        if(strfor[itmp-1]=='\n')
                   2213:          strfor[itmp-1]='\0';
                   2214:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2215:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2216:       }
                   2217:     }
1.187     brouard  2218:     for (i=1;i<=n;i++) { /* For each direction i */
                   2219:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2220:       fptt=(*fret); 
                   2221: #ifdef DEBUG
1.203     brouard  2222:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2223:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2224: #endif
1.203     brouard  2225:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2226:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2227: #ifdef LINMINORIGINAL
1.188     brouard  2228:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2229: #else
                   2230:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2231:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2232: #endif
                   2233:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2234:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2235:                                /* because that direction will be replaced unless the gain del is small */
                   2236:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2237:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2238:                                /* with the new direction. */
                   2239:                                del=fabs(fptt-(*fret)); 
                   2240:                                ibig=i; 
1.126     brouard  2241:       } 
                   2242: #ifdef DEBUG
                   2243:       printf("%d %.12e",i,(*fret));
                   2244:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2245:       for (j=1;j<=n;j++) {
1.224     brouard  2246:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2247:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2248:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2249:       }
                   2250:       for(j=1;j<=n;j++) {
1.225     brouard  2251:                                printf(" p(%d)=%.12e",j,p[j]);
                   2252:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2253:       }
                   2254:       printf("\n");
                   2255:       fprintf(ficlog,"\n");
                   2256: #endif
1.187     brouard  2257:     } /* end loop on each direction i */
                   2258:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2259:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2260:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2261:       for(j=1;j<=n;j++) {
1.225     brouard  2262:                                if(flatdir[j] >0){
                   2263:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2264:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2265:                                }
                   2266:                                /* printf("\n"); */
                   2267:                                /* fprintf(ficlog,"\n"); */
                   2268:                        }
1.243     brouard  2269:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2270:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2271:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2272:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2273:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2274:       /* decreased of more than 3.84  */
                   2275:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2276:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2277:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2278:                        
1.188     brouard  2279:       /* Starting the program with initial values given by a former maximization will simply change */
                   2280:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2281:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2282:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2283: #ifdef DEBUG
                   2284:       int k[2],l;
                   2285:       k[0]=1;
                   2286:       k[1]=-1;
                   2287:       printf("Max: %.12e",(*func)(p));
                   2288:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2289:       for (j=1;j<=n;j++) {
                   2290:        printf(" %.12e",p[j]);
                   2291:        fprintf(ficlog," %.12e",p[j]);
                   2292:       }
                   2293:       printf("\n");
                   2294:       fprintf(ficlog,"\n");
                   2295:       for(l=0;l<=1;l++) {
                   2296:        for (j=1;j<=n;j++) {
                   2297:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2298:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2299:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2300:        }
                   2301:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2302:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2303:       }
                   2304: #endif
                   2305: 
1.224     brouard  2306: #ifdef LINMINORIGINAL
                   2307: #else
                   2308:       free_ivector(flatdir,1,n); 
                   2309: #endif
1.126     brouard  2310:       free_vector(xit,1,n); 
                   2311:       free_vector(xits,1,n); 
                   2312:       free_vector(ptt,1,n); 
                   2313:       free_vector(pt,1,n); 
                   2314:       return; 
1.192     brouard  2315:     } /* enough precision */ 
1.240     brouard  2316:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2317:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2318:       ptt[j]=2.0*p[j]-pt[j]; 
                   2319:       xit[j]=p[j]-pt[j]; 
                   2320:       pt[j]=p[j]; 
                   2321:     } 
1.181     brouard  2322:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2323: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2324:                if (*iter <=4) {
1.225     brouard  2325: #else
                   2326: #endif
1.224     brouard  2327: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2328: #else
1.161     brouard  2329:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2330: #endif
1.162     brouard  2331:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2332:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2333:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2334:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2335:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2336:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2337:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2338:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2339:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2340:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2341:       /* mu² and del² are equal when f3=f1 */
                   2342:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2343:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2344:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2345:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2346: #ifdef NRCORIGINAL
                   2347:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2348: #else
                   2349:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2350:       t= t- del*SQR(fp-fptt);
1.183     brouard  2351: #endif
1.202     brouard  2352:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2353: #ifdef DEBUG
1.181     brouard  2354:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2355:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2356:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2357:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2358:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2359:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2360:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2361:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2362: #endif
1.183     brouard  2363: #ifdef POWELLORIGINAL
                   2364:       if (t < 0.0) { /* Then we use it for new direction */
                   2365: #else
1.182     brouard  2366:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2367:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2368:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2369:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2370:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2371:       } 
1.181     brouard  2372:       if (directest < 0.0) { /* Then we use it for new direction */
                   2373: #endif
1.191     brouard  2374: #ifdef DEBUGLINMIN
1.234     brouard  2375:        printf("Before linmin in direction P%d-P0\n",n);
                   2376:        for (j=1;j<=n;j++) {
                   2377:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2378:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2379:          if(j % ncovmodel == 0){
                   2380:            printf("\n");
                   2381:            fprintf(ficlog,"\n");
                   2382:          }
                   2383:        }
1.224     brouard  2384: #endif
                   2385: #ifdef LINMINORIGINAL
1.234     brouard  2386:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2387: #else
1.234     brouard  2388:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2389:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2390: #endif
1.234     brouard  2391:        
1.191     brouard  2392: #ifdef DEBUGLINMIN
1.234     brouard  2393:        for (j=1;j<=n;j++) { 
                   2394:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2395:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2396:          if(j % ncovmodel == 0){
                   2397:            printf("\n");
                   2398:            fprintf(ficlog,"\n");
                   2399:          }
                   2400:        }
1.224     brouard  2401: #endif
1.234     brouard  2402:        for (j=1;j<=n;j++) { 
                   2403:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2404:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2405:        }
1.224     brouard  2406: #ifdef LINMINORIGINAL
                   2407: #else
1.234     brouard  2408:        for (j=1, flatd=0;j<=n;j++) {
                   2409:          if(flatdir[j]>0)
                   2410:            flatd++;
                   2411:        }
                   2412:        if(flatd >0){
1.255     brouard  2413:          printf("%d flat directions: ",flatd);
                   2414:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2415:          for (j=1;j<=n;j++) { 
                   2416:            if(flatdir[j]>0){
                   2417:              printf("%d ",j);
                   2418:              fprintf(ficlog,"%d ",j);
                   2419:            }
                   2420:          }
                   2421:          printf("\n");
                   2422:          fprintf(ficlog,"\n");
                   2423:        }
1.191     brouard  2424: #endif
1.234     brouard  2425:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2426:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2427:        
1.126     brouard  2428: #ifdef DEBUG
1.234     brouard  2429:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2430:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2431:        for(j=1;j<=n;j++){
                   2432:          printf(" %lf",xit[j]);
                   2433:          fprintf(ficlog," %lf",xit[j]);
                   2434:        }
                   2435:        printf("\n");
                   2436:        fprintf(ficlog,"\n");
1.126     brouard  2437: #endif
1.192     brouard  2438:       } /* end of t or directest negative */
1.224     brouard  2439: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2440: #else
1.234     brouard  2441:       } /* end if (fptt < fp)  */
1.192     brouard  2442: #endif
1.225     brouard  2443: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2444:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2445: #else
1.224     brouard  2446: #endif
1.234     brouard  2447:                } /* loop iteration */ 
1.126     brouard  2448: } 
1.234     brouard  2449:   
1.126     brouard  2450: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2451:   
1.235     brouard  2452:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2453:   {
1.235     brouard  2454:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2455:        (and selected quantitative values in nres)
                   2456:        by left multiplying the unit
1.234     brouard  2457:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2458:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2459:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2460:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2461:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2462:   /* Initial matrix pimij */
                   2463:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2464:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2465:   /*  0,                   0                  , 1} */
                   2466:   /*
                   2467:    * and after some iteration: */
                   2468:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2469:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2470:   /*  0,                   0                  , 1} */
                   2471:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2472:   /* {0.51571254859325999, 0.4842874514067399, */
                   2473:   /*  0.51326036147820708, 0.48673963852179264} */
                   2474:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2475:     
1.126     brouard  2476:   int i, ii,j,k;
1.209     brouard  2477:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2478:   /* double **matprod2(); */ /* test */
1.218     brouard  2479:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2480:   double **newm;
1.209     brouard  2481:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2482:   int ncvloop=0;
1.169     brouard  2483:   
1.209     brouard  2484:   min=vector(1,nlstate);
                   2485:   max=vector(1,nlstate);
                   2486:   meandiff=vector(1,nlstate);
                   2487: 
1.218     brouard  2488:        /* Starting with matrix unity */
1.126     brouard  2489:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2490:     for (j=1;j<=nlstate+ndeath;j++){
                   2491:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2492:     }
1.169     brouard  2493:   
                   2494:   cov[1]=1.;
                   2495:   
                   2496:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2497:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2498:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2499:     ncvloop++;
1.126     brouard  2500:     newm=savm;
                   2501:     /* Covariates have to be included here again */
1.138     brouard  2502:     cov[2]=agefin;
1.187     brouard  2503:     if(nagesqr==1)
                   2504:       cov[3]= agefin*agefin;;
1.234     brouard  2505:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2506:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2507:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2508:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2509:     }
                   2510:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2511:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2512:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2513:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2514:     }
1.237     brouard  2515:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2516:       if(Dummy[Tvar[Tage[k]]]){
                   2517:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2518:       } else{
1.235     brouard  2519:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2520:       }
1.235     brouard  2521:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2522:     }
1.237     brouard  2523:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2524:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2525:       if(Dummy[Tvard[k][1]==0]){
                   2526:        if(Dummy[Tvard[k][2]==0]){
                   2527:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2528:        }else{
                   2529:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2530:        }
                   2531:       }else{
                   2532:        if(Dummy[Tvard[k][2]==0]){
                   2533:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2534:        }else{
                   2535:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2536:        }
                   2537:       }
1.234     brouard  2538:     }
1.138     brouard  2539:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2540:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2541:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2542:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2543:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2544:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2545:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2546:     
1.126     brouard  2547:     savm=oldm;
                   2548:     oldm=newm;
1.209     brouard  2549: 
                   2550:     for(j=1; j<=nlstate; j++){
                   2551:       max[j]=0.;
                   2552:       min[j]=1.;
                   2553:     }
                   2554:     for(i=1;i<=nlstate;i++){
                   2555:       sumnew=0;
                   2556:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2557:       for(j=1; j<=nlstate; j++){ 
                   2558:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2559:        max[j]=FMAX(max[j],prlim[i][j]);
                   2560:        min[j]=FMIN(min[j],prlim[i][j]);
                   2561:       }
                   2562:     }
                   2563: 
1.126     brouard  2564:     maxmax=0.;
1.209     brouard  2565:     for(j=1; j<=nlstate; j++){
                   2566:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2567:       maxmax=FMAX(maxmax,meandiff[j]);
                   2568:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2569:     } /* j loop */
1.203     brouard  2570:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2571:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2572:     if(maxmax < ftolpl){
1.209     brouard  2573:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2574:       free_vector(min,1,nlstate);
                   2575:       free_vector(max,1,nlstate);
                   2576:       free_vector(meandiff,1,nlstate);
1.126     brouard  2577:       return prlim;
                   2578:     }
1.169     brouard  2579:   } /* age loop */
1.208     brouard  2580:     /* After some age loop it doesn't converge */
1.209     brouard  2581:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2582: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2583:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2584:   free_vector(min,1,nlstate);
                   2585:   free_vector(max,1,nlstate);
                   2586:   free_vector(meandiff,1,nlstate);
1.208     brouard  2587:   
1.169     brouard  2588:   return prlim; /* should not reach here */
1.126     brouard  2589: }
                   2590: 
1.217     brouard  2591: 
                   2592:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2593: 
1.218     brouard  2594:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2595:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2596:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2597: {
1.218     brouard  2598:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2599:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2600:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2601:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2602:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2603:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2604:   /* Initial matrix pimij */
                   2605:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2606:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2607:   /*  0,                   0                  , 1} */
                   2608:   /*
                   2609:    * and after some iteration: */
                   2610:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2611:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2612:   /*  0,                   0                  , 1} */
                   2613:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2614:   /* {0.51571254859325999, 0.4842874514067399, */
                   2615:   /*  0.51326036147820708, 0.48673963852179264} */
                   2616:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2617: 
                   2618:   int i, ii,j,k;
1.247     brouard  2619:   int first=0;
1.217     brouard  2620:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2621:   /* double **matprod2(); */ /* test */
                   2622:   double **out, cov[NCOVMAX+1], **bmij();
                   2623:   double **newm;
1.218     brouard  2624:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2625:   double        **oldm, **savm;  /* for use */
                   2626: 
1.217     brouard  2627:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2628:   int ncvloop=0;
                   2629:   
                   2630:   min=vector(1,nlstate);
                   2631:   max=vector(1,nlstate);
                   2632:   meandiff=vector(1,nlstate);
                   2633: 
1.218     brouard  2634:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2635:        oldm=oldms; savm=savms;
                   2636: 
                   2637:        /* Starting with matrix unity */
                   2638:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2639:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2640:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2641:     }
                   2642:   
                   2643:   cov[1]=1.;
                   2644:   
                   2645:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2646:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2647:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2648:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2649:     ncvloop++;
1.218     brouard  2650:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2651:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2652:     /* Covariates have to be included here again */
                   2653:     cov[2]=agefin;
                   2654:     if(nagesqr==1)
                   2655:       cov[3]= agefin*agefin;;
1.242     brouard  2656:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2657:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2658:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2659:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2660:     }
                   2661:     /* for (k=1; k<=cptcovn;k++) { */
                   2662:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2663:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2664:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2665:     /* } */
                   2666:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2667:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2668:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2669:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2670:     }
                   2671:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2672:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2673:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2674:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2675:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2676:       if(Dummy[Tvar[Tage[k]]]){
                   2677:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2678:       } else{
                   2679:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2680:       }
                   2681:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2682:     }
                   2683:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2684:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2685:       if(Dummy[Tvard[k][1]==0]){
                   2686:        if(Dummy[Tvard[k][2]==0]){
                   2687:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2688:        }else{
                   2689:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2690:        }
                   2691:       }else{
                   2692:        if(Dummy[Tvard[k][2]==0]){
                   2693:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2694:        }else{
                   2695:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2696:        }
                   2697:       }
1.217     brouard  2698:     }
                   2699:     
                   2700:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2701:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2702:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2703:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2704:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2705:                /* ij should be linked to the correct index of cov */
                   2706:                /* age and covariate values ij are in 'cov', but we need to pass
                   2707:                 * ij for the observed prevalence at age and status and covariate
                   2708:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2709:                 */
                   2710:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2711:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2712:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2713:     savm=oldm;
                   2714:     oldm=newm;
                   2715:     for(j=1; j<=nlstate; j++){
                   2716:       max[j]=0.;
                   2717:       min[j]=1.;
                   2718:     }
                   2719:     for(j=1; j<=nlstate; j++){ 
                   2720:       for(i=1;i<=nlstate;i++){
1.234     brouard  2721:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2722:        bprlim[i][j]= newm[i][j];
                   2723:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2724:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2725:       }
                   2726:     }
1.218     brouard  2727:                
1.217     brouard  2728:     maxmax=0.;
                   2729:     for(i=1; i<=nlstate; i++){
                   2730:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2731:       maxmax=FMAX(maxmax,meandiff[i]);
                   2732:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2733:     } /* j loop */
                   2734:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2735:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2736:     if(maxmax < ftolpl){
1.220     brouard  2737:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2738:       free_vector(min,1,nlstate);
                   2739:       free_vector(max,1,nlstate);
                   2740:       free_vector(meandiff,1,nlstate);
                   2741:       return bprlim;
                   2742:     }
                   2743:   } /* age loop */
                   2744:     /* After some age loop it doesn't converge */
1.247     brouard  2745:   if(first){
                   2746:     first=1;
                   2747:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2748: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2749:   }
                   2750:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2751: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2752:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2753:   free_vector(min,1,nlstate);
                   2754:   free_vector(max,1,nlstate);
                   2755:   free_vector(meandiff,1,nlstate);
                   2756:   
                   2757:   return bprlim; /* should not reach here */
                   2758: }
                   2759: 
1.126     brouard  2760: /*************** transition probabilities ***************/ 
                   2761: 
                   2762: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2763: {
1.138     brouard  2764:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2765:      computes the probability to be observed in state j being in state i by appying the
                   2766:      model to the ncovmodel covariates (including constant and age).
                   2767:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2768:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2769:      ncth covariate in the global vector x is given by the formula:
                   2770:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2771:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2772:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2773:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2774:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2775:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2776:   */
                   2777:   double s1, lnpijopii;
1.126     brouard  2778:   /*double t34;*/
1.164     brouard  2779:   int i,j, nc, ii, jj;
1.126     brouard  2780: 
1.223     brouard  2781:   for(i=1; i<= nlstate; i++){
                   2782:     for(j=1; j<i;j++){
                   2783:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2784:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2785:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2786:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2787:       }
                   2788:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2789:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2790:     }
                   2791:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2792:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2793:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2794:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2795:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2796:       }
                   2797:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2798:     }
                   2799:   }
1.218     brouard  2800:   
1.223     brouard  2801:   for(i=1; i<= nlstate; i++){
                   2802:     s1=0;
                   2803:     for(j=1; j<i; j++){
                   2804:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2805:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2806:     }
                   2807:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2808:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2809:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2810:     }
                   2811:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2812:     ps[i][i]=1./(s1+1.);
                   2813:     /* Computing other pijs */
                   2814:     for(j=1; j<i; j++)
                   2815:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2816:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2817:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2818:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2819:   } /* end i */
1.218     brouard  2820:   
1.223     brouard  2821:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2822:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2823:       ps[ii][jj]=0;
                   2824:       ps[ii][ii]=1;
                   2825:     }
                   2826:   }
1.218     brouard  2827:   
                   2828:   
1.223     brouard  2829:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2830:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2831:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2832:   /*   } */
                   2833:   /*   printf("\n "); */
                   2834:   /* } */
                   2835:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2836:   /*
                   2837:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2838:                goto end;*/
1.223     brouard  2839:   return ps;
1.126     brouard  2840: }
                   2841: 
1.218     brouard  2842: /*************** backward transition probabilities ***************/ 
                   2843: 
                   2844:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2845: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2846:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2847: {
1.222     brouard  2848:   /* Computes the backward probability at age agefin and covariate ij
                   2849:    * and returns in **ps as well as **bmij.
                   2850:    */
1.218     brouard  2851:   int i, ii, j,k;
1.222     brouard  2852:   
                   2853:   double **out, **pmij();
                   2854:   double sumnew=0.;
1.218     brouard  2855:   double agefin;
1.222     brouard  2856:   
                   2857:   double **dnewm, **dsavm, **doldm;
                   2858:   double **bbmij;
                   2859:   
1.218     brouard  2860:   doldm=ddoldms; /* global pointers */
1.222     brouard  2861:   dnewm=ddnewms;
                   2862:   dsavm=ddsavms;
                   2863:   
                   2864:   agefin=cov[2];
                   2865:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2866:      the observed prevalence (with this covariate ij) */
                   2867:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2868:   /* We do have the matrix Px in savm  and we need pij */
                   2869:   for (j=1;j<=nlstate+ndeath;j++){
                   2870:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2871:     for (ii=1;ii<=nlstate;ii++){
                   2872:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2873:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2874:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2875:       if(sumnew >= 1.e-10){
                   2876:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2877:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2878:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2879:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2880:        /* }else */
                   2881:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2882:       }else{
1.242     brouard  2883:        ;
                   2884:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2885:       }
                   2886:     } /*End ii */
                   2887:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2888:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2889:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2890:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2891:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2892:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2893:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2894:   for (j=1;j<=nlstate+ndeath;j++){
                   2895:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2896:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2897:     }
                   2898:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2899:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2900:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2901:   /* end bmij */
                   2902:   return ps; 
1.218     brouard  2903: }
1.217     brouard  2904: /*************** transition probabilities ***************/ 
                   2905: 
1.218     brouard  2906: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2907: {
                   2908:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2909:      computes the probability to be observed in state j being in state i by appying the
                   2910:      model to the ncovmodel covariates (including constant and age).
                   2911:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2912:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2913:      ncth covariate in the global vector x is given by the formula:
                   2914:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2915:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2916:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2917:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2918:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2919:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2920:   */
                   2921:   double s1, lnpijopii;
                   2922:   /*double t34;*/
                   2923:   int i,j, nc, ii, jj;
                   2924: 
1.234     brouard  2925:   for(i=1; i<= nlstate; i++){
                   2926:     for(j=1; j<i;j++){
                   2927:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2928:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2929:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2930:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2931:       }
                   2932:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2933:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2934:     }
                   2935:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2936:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2937:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2938:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2939:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2940:       }
                   2941:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2942:     }
                   2943:   }
                   2944:   
                   2945:   for(i=1; i<= nlstate; i++){
                   2946:     s1=0;
                   2947:     for(j=1; j<i; j++){
                   2948:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2949:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2950:     }
                   2951:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2952:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2953:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2954:     }
                   2955:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2956:     ps[i][i]=1./(s1+1.);
                   2957:     /* Computing other pijs */
                   2958:     for(j=1; j<i; j++)
                   2959:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2960:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2961:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2962:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2963:   } /* end i */
                   2964:   
                   2965:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2966:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2967:       ps[ii][jj]=0;
                   2968:       ps[ii][ii]=1;
                   2969:     }
                   2970:   }
                   2971:   /* Added for backcast */ /* Transposed matrix too */
                   2972:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2973:     s1=0.;
                   2974:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2975:       s1+=ps[ii][jj];
                   2976:     }
                   2977:     for(ii=1; ii<= nlstate; ii++){
                   2978:       ps[ii][jj]=ps[ii][jj]/s1;
                   2979:     }
                   2980:   }
                   2981:   /* Transposition */
                   2982:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2983:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2984:       s1=ps[ii][jj];
                   2985:       ps[ii][jj]=ps[jj][ii];
                   2986:       ps[jj][ii]=s1;
                   2987:     }
                   2988:   }
                   2989:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2990:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2991:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2992:   /*   } */
                   2993:   /*   printf("\n "); */
                   2994:   /* } */
                   2995:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2996:   /*
                   2997:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   2998:     goto end;*/
                   2999:   return ps;
1.217     brouard  3000: }
                   3001: 
                   3002: 
1.126     brouard  3003: /**************** Product of 2 matrices ******************/
                   3004: 
1.145     brouard  3005: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3006: {
                   3007:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3008:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3009:   /* in, b, out are matrice of pointers which should have been initialized 
                   3010:      before: only the contents of out is modified. The function returns
                   3011:      a pointer to pointers identical to out */
1.145     brouard  3012:   int i, j, k;
1.126     brouard  3013:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3014:     for(k=ncolol; k<=ncoloh; k++){
                   3015:       out[i][k]=0.;
                   3016:       for(j=ncl; j<=nch; j++)
                   3017:        out[i][k] +=in[i][j]*b[j][k];
                   3018:     }
1.126     brouard  3019:   return out;
                   3020: }
                   3021: 
                   3022: 
                   3023: /************* Higher Matrix Product ***************/
                   3024: 
1.235     brouard  3025: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3026: {
1.218     brouard  3027:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3028:      'nhstepm*hstepm*stepm' months (i.e. until
                   3029:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3030:      nhstepm*hstepm matrices. 
                   3031:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3032:      (typically every 2 years instead of every month which is too big 
                   3033:      for the memory).
                   3034:      Model is determined by parameters x and covariates have to be 
                   3035:      included manually here. 
                   3036: 
                   3037:      */
                   3038: 
                   3039:   int i, j, d, h, k;
1.131     brouard  3040:   double **out, cov[NCOVMAX+1];
1.126     brouard  3041:   double **newm;
1.187     brouard  3042:   double agexact;
1.214     brouard  3043:   double agebegin, ageend;
1.126     brouard  3044: 
                   3045:   /* Hstepm could be zero and should return the unit matrix */
                   3046:   for (i=1;i<=nlstate+ndeath;i++)
                   3047:     for (j=1;j<=nlstate+ndeath;j++){
                   3048:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3049:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3050:     }
                   3051:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3052:   for(h=1; h <=nhstepm; h++){
                   3053:     for(d=1; d <=hstepm; d++){
                   3054:       newm=savm;
                   3055:       /* Covariates have to be included here again */
                   3056:       cov[1]=1.;
1.214     brouard  3057:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3058:       cov[2]=agexact;
                   3059:       if(nagesqr==1)
1.227     brouard  3060:        cov[3]= agexact*agexact;
1.235     brouard  3061:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3062:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3063:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3064:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3065:       }
                   3066:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3067:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3068:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3069:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3070:       }
                   3071:       for (k=1; k<=cptcovage;k++){
                   3072:        if(Dummy[Tvar[Tage[k]]]){
                   3073:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3074:        } else{
                   3075:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3076:        }
                   3077:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3078:       }
                   3079:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3080:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3081:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3082:       }
                   3083:       /* for (k=1; k<=cptcovn;k++)  */
                   3084:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3085:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3086:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3087:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3088:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3089:       
                   3090:       
1.126     brouard  3091:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3092:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3093:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3094:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3095:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3096:       /* if((int)age == 70){ */
                   3097:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3098:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3099:       /*         printf("%d pmmij ",i); */
                   3100:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3101:       /*           printf("%f ",pmmij[i][j]); */
                   3102:       /*         } */
                   3103:       /*         printf(" oldm "); */
                   3104:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3105:       /*           printf("%f ",oldm[i][j]); */
                   3106:       /*         } */
                   3107:       /*         printf("\n"); */
                   3108:       /*       } */
                   3109:       /* } */
1.126     brouard  3110:       savm=oldm;
                   3111:       oldm=newm;
                   3112:     }
                   3113:     for(i=1; i<=nlstate+ndeath; i++)
                   3114:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3115:                                po[i][j][h]=newm[i][j];
                   3116:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3117:       }
1.128     brouard  3118:     /*printf("h=%d ",h);*/
1.126     brouard  3119:   } /* end h */
1.218     brouard  3120:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3121:   return po;
                   3122: }
                   3123: 
1.217     brouard  3124: /************* Higher Back Matrix Product ***************/
1.218     brouard  3125: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3126: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3127: {
1.218     brouard  3128:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3129:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3130:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3131:      nhstepm*hstepm matrices.
                   3132:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3133:      (typically every 2 years instead of every month which is too big
1.217     brouard  3134:      for the memory).
1.218     brouard  3135:      Model is determined by parameters x and covariates have to be
                   3136:      included manually here.
1.217     brouard  3137: 
1.222     brouard  3138:   */
1.217     brouard  3139: 
                   3140:   int i, j, d, h, k;
                   3141:   double **out, cov[NCOVMAX+1];
                   3142:   double **newm;
                   3143:   double agexact;
                   3144:   double agebegin, ageend;
1.222     brouard  3145:   double **oldm, **savm;
1.217     brouard  3146: 
1.222     brouard  3147:   oldm=oldms;savm=savms;
1.217     brouard  3148:   /* Hstepm could be zero and should return the unit matrix */
                   3149:   for (i=1;i<=nlstate+ndeath;i++)
                   3150:     for (j=1;j<=nlstate+ndeath;j++){
                   3151:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3152:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3153:     }
                   3154:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3155:   for(h=1; h <=nhstepm; h++){
                   3156:     for(d=1; d <=hstepm; d++){
                   3157:       newm=savm;
                   3158:       /* Covariates have to be included here again */
                   3159:       cov[1]=1.;
                   3160:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3161:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3162:       cov[2]=agexact;
                   3163:       if(nagesqr==1)
1.222     brouard  3164:        cov[3]= agexact*agexact;
1.218     brouard  3165:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3166:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3167:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3168:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3169:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3170:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3171:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3172:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3173:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3174:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3175:                        
                   3176:                        
1.217     brouard  3177:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3178:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3179:       /* Careful transposed matrix */
1.222     brouard  3180:       /* age is in cov[2] */
1.218     brouard  3181:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3182:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3183:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3184:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3185:       /* if((int)age == 70){ */
                   3186:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3187:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3188:       /*         printf("%d pmmij ",i); */
                   3189:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3190:       /*           printf("%f ",pmmij[i][j]); */
                   3191:       /*         } */
                   3192:       /*         printf(" oldm "); */
                   3193:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3194:       /*           printf("%f ",oldm[i][j]); */
                   3195:       /*         } */
                   3196:       /*         printf("\n"); */
                   3197:       /*       } */
                   3198:       /* } */
                   3199:       savm=oldm;
                   3200:       oldm=newm;
                   3201:     }
                   3202:     for(i=1; i<=nlstate+ndeath; i++)
                   3203:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3204:        po[i][j][h]=newm[i][j];
                   3205:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3206:       }
                   3207:     /*printf("h=%d ",h);*/
                   3208:   } /* end h */
1.222     brouard  3209:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3210:   return po;
                   3211: }
                   3212: 
                   3213: 
1.162     brouard  3214: #ifdef NLOPT
                   3215:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3216:   double fret;
                   3217:   double *xt;
                   3218:   int j;
                   3219:   myfunc_data *d2 = (myfunc_data *) pd;
                   3220: /* xt = (p1-1); */
                   3221:   xt=vector(1,n); 
                   3222:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3223: 
                   3224:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3225:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3226:   printf("Function = %.12lf ",fret);
                   3227:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3228:   printf("\n");
                   3229:  free_vector(xt,1,n);
                   3230:   return fret;
                   3231: }
                   3232: #endif
1.126     brouard  3233: 
                   3234: /*************** log-likelihood *************/
                   3235: double func( double *x)
                   3236: {
1.226     brouard  3237:   int i, ii, j, k, mi, d, kk;
                   3238:   int ioffset=0;
                   3239:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3240:   double **out;
                   3241:   double lli; /* Individual log likelihood */
                   3242:   int s1, s2;
1.228     brouard  3243:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3244:   double bbh, survp;
                   3245:   long ipmx;
                   3246:   double agexact;
                   3247:   /*extern weight */
                   3248:   /* We are differentiating ll according to initial status */
                   3249:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3250:   /*for(i=1;i<imx;i++) 
                   3251:     printf(" %d\n",s[4][i]);
                   3252:   */
1.162     brouard  3253: 
1.226     brouard  3254:   ++countcallfunc;
1.162     brouard  3255: 
1.226     brouard  3256:   cov[1]=1.;
1.126     brouard  3257: 
1.226     brouard  3258:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3259:   ioffset=0;
1.226     brouard  3260:   if(mle==1){
                   3261:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3262:       /* Computes the values of the ncovmodel covariates of the model
                   3263:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3264:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3265:         to be observed in j being in i according to the model.
                   3266:       */
1.243     brouard  3267:       ioffset=2+nagesqr ;
1.233     brouard  3268:    /* Fixed */
1.234     brouard  3269:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3270:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3271:       }
1.226     brouard  3272:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3273:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3274:         has been calculated etc */
                   3275:       /* For an individual i, wav[i] gives the number of effective waves */
                   3276:       /* We compute the contribution to Likelihood of each effective transition
                   3277:         mw[mi][i] is real wave of the mi th effectve wave */
                   3278:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3279:         s2=s[mw[mi+1][i]][i];
                   3280:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3281:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3282:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3283:       */
                   3284:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3285:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3286:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3287:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3288:        }
                   3289:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3290:          for (j=1;j<=nlstate+ndeath;j++){
                   3291:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3292:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3293:          }
                   3294:        for(d=0; d<dh[mi][i]; d++){
                   3295:          newm=savm;
                   3296:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3297:          cov[2]=agexact;
                   3298:          if(nagesqr==1)
                   3299:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3300:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3301:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3302:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3303:          else
                   3304:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3305:          }
                   3306:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3307:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3308:          savm=oldm;
                   3309:          oldm=newm;
                   3310:        } /* end mult */
                   3311:        
                   3312:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3313:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3314:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3315:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3316:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3317:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3318:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3319:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3320:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3321:                                 * -stepm/2 to stepm/2 .
                   3322:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3323:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3324:                                 */
1.234     brouard  3325:        s1=s[mw[mi][i]][i];
                   3326:        s2=s[mw[mi+1][i]][i];
                   3327:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3328:        /* bias bh is positive if real duration
                   3329:         * is higher than the multiple of stepm and negative otherwise.
                   3330:         */
                   3331:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3332:        if( s2 > nlstate){ 
                   3333:          /* i.e. if s2 is a death state and if the date of death is known 
                   3334:             then the contribution to the likelihood is the probability to 
                   3335:             die between last step unit time and current  step unit time, 
                   3336:             which is also equal to probability to die before dh 
                   3337:             minus probability to die before dh-stepm . 
                   3338:             In version up to 0.92 likelihood was computed
                   3339:             as if date of death was unknown. Death was treated as any other
                   3340:             health state: the date of the interview describes the actual state
                   3341:             and not the date of a change in health state. The former idea was
                   3342:             to consider that at each interview the state was recorded
                   3343:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3344:             introduced the exact date of death then we should have modified
                   3345:             the contribution of an exact death to the likelihood. This new
                   3346:             contribution is smaller and very dependent of the step unit
                   3347:             stepm. It is no more the probability to die between last interview
                   3348:             and month of death but the probability to survive from last
                   3349:             interview up to one month before death multiplied by the
                   3350:             probability to die within a month. Thanks to Chris
                   3351:             Jackson for correcting this bug.  Former versions increased
                   3352:             mortality artificially. The bad side is that we add another loop
                   3353:             which slows down the processing. The difference can be up to 10%
                   3354:             lower mortality.
                   3355:          */
                   3356:          /* If, at the beginning of the maximization mostly, the
                   3357:             cumulative probability or probability to be dead is
                   3358:             constant (ie = 1) over time d, the difference is equal to
                   3359:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3360:             s1 at precedent wave, to be dead a month before current
                   3361:             wave is equal to probability, being at state s1 at
                   3362:             precedent wave, to be dead at mont of the current
                   3363:             wave. Then the observed probability (that this person died)
                   3364:             is null according to current estimated parameter. In fact,
                   3365:             it should be very low but not zero otherwise the log go to
                   3366:             infinity.
                   3367:          */
1.183     brouard  3368: /* #ifdef INFINITYORIGINAL */
                   3369: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3370: /* #else */
                   3371: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3372: /*         lli=log(mytinydouble); */
                   3373: /*       else */
                   3374: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3375: /* #endif */
1.226     brouard  3376:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3377:          
1.226     brouard  3378:        } else if  ( s2==-1 ) { /* alive */
                   3379:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3380:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3381:          /*survp += out[s1][j]; */
                   3382:          lli= log(survp);
                   3383:        }
                   3384:        else if  (s2==-4) { 
                   3385:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3386:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3387:          lli= log(survp); 
                   3388:        } 
                   3389:        else if  (s2==-5) { 
                   3390:          for (j=1,survp=0. ; j<=2; j++)  
                   3391:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3392:          lli= log(survp); 
                   3393:        } 
                   3394:        else{
                   3395:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3396:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3397:        } 
                   3398:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3399:        /*if(lli ==000.0)*/
                   3400:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3401:        ipmx +=1;
                   3402:        sw += weight[i];
                   3403:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3404:        /* if (lli < log(mytinydouble)){ */
                   3405:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3406:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3407:        /* } */
                   3408:       } /* end of wave */
                   3409:     } /* end of individual */
                   3410:   }  else if(mle==2){
                   3411:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3412:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3413:       for(mi=1; mi<= wav[i]-1; mi++){
                   3414:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3415:          for (j=1;j<=nlstate+ndeath;j++){
                   3416:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3417:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3418:          }
                   3419:        for(d=0; d<=dh[mi][i]; d++){
                   3420:          newm=savm;
                   3421:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3422:          cov[2]=agexact;
                   3423:          if(nagesqr==1)
                   3424:            cov[3]= agexact*agexact;
                   3425:          for (kk=1; kk<=cptcovage;kk++) {
                   3426:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3427:          }
                   3428:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3429:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3430:          savm=oldm;
                   3431:          oldm=newm;
                   3432:        } /* end mult */
                   3433:       
                   3434:        s1=s[mw[mi][i]][i];
                   3435:        s2=s[mw[mi+1][i]][i];
                   3436:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3437:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3438:        ipmx +=1;
                   3439:        sw += weight[i];
                   3440:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3441:       } /* end of wave */
                   3442:     } /* end of individual */
                   3443:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3444:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3445:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3446:       for(mi=1; mi<= wav[i]-1; mi++){
                   3447:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3448:          for (j=1;j<=nlstate+ndeath;j++){
                   3449:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3450:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3451:          }
                   3452:        for(d=0; d<dh[mi][i]; d++){
                   3453:          newm=savm;
                   3454:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3455:          cov[2]=agexact;
                   3456:          if(nagesqr==1)
                   3457:            cov[3]= agexact*agexact;
                   3458:          for (kk=1; kk<=cptcovage;kk++) {
                   3459:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3460:          }
                   3461:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3462:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3463:          savm=oldm;
                   3464:          oldm=newm;
                   3465:        } /* end mult */
                   3466:       
                   3467:        s1=s[mw[mi][i]][i];
                   3468:        s2=s[mw[mi+1][i]][i];
                   3469:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3470:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3471:        ipmx +=1;
                   3472:        sw += weight[i];
                   3473:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3474:       } /* end of wave */
                   3475:     } /* end of individual */
                   3476:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3477:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3478:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3479:       for(mi=1; mi<= wav[i]-1; mi++){
                   3480:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3481:          for (j=1;j<=nlstate+ndeath;j++){
                   3482:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3483:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3484:          }
                   3485:        for(d=0; d<dh[mi][i]; d++){
                   3486:          newm=savm;
                   3487:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3488:          cov[2]=agexact;
                   3489:          if(nagesqr==1)
                   3490:            cov[3]= agexact*agexact;
                   3491:          for (kk=1; kk<=cptcovage;kk++) {
                   3492:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3493:          }
1.126     brouard  3494:        
1.226     brouard  3495:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3496:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3497:          savm=oldm;
                   3498:          oldm=newm;
                   3499:        } /* end mult */
                   3500:       
                   3501:        s1=s[mw[mi][i]][i];
                   3502:        s2=s[mw[mi+1][i]][i];
                   3503:        if( s2 > nlstate){ 
                   3504:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3505:        } else if  ( s2==-1 ) { /* alive */
                   3506:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3507:            survp += out[s1][j];
                   3508:          lli= log(survp);
                   3509:        }else{
                   3510:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3511:        }
                   3512:        ipmx +=1;
                   3513:        sw += weight[i];
                   3514:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3515: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3516:       } /* end of wave */
                   3517:     } /* end of individual */
                   3518:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3519:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3520:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3521:       for(mi=1; mi<= wav[i]-1; mi++){
                   3522:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3523:          for (j=1;j<=nlstate+ndeath;j++){
                   3524:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3525:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3526:          }
                   3527:        for(d=0; d<dh[mi][i]; d++){
                   3528:          newm=savm;
                   3529:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3530:          cov[2]=agexact;
                   3531:          if(nagesqr==1)
                   3532:            cov[3]= agexact*agexact;
                   3533:          for (kk=1; kk<=cptcovage;kk++) {
                   3534:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3535:          }
1.126     brouard  3536:        
1.226     brouard  3537:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3538:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3539:          savm=oldm;
                   3540:          oldm=newm;
                   3541:        } /* end mult */
                   3542:       
                   3543:        s1=s[mw[mi][i]][i];
                   3544:        s2=s[mw[mi+1][i]][i];
                   3545:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3546:        ipmx +=1;
                   3547:        sw += weight[i];
                   3548:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3549:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3550:       } /* end of wave */
                   3551:     } /* end of individual */
                   3552:   } /* End of if */
                   3553:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3554:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3555:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3556:   return -l;
1.126     brouard  3557: }
                   3558: 
                   3559: /*************** log-likelihood *************/
                   3560: double funcone( double *x)
                   3561: {
1.228     brouard  3562:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3563:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3564:   int ioffset=0;
1.131     brouard  3565:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3566:   double **out;
                   3567:   double lli; /* Individual log likelihood */
                   3568:   double llt;
                   3569:   int s1, s2;
1.228     brouard  3570:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3571: 
1.126     brouard  3572:   double bbh, survp;
1.187     brouard  3573:   double agexact;
1.214     brouard  3574:   double agebegin, ageend;
1.126     brouard  3575:   /*extern weight */
                   3576:   /* We are differentiating ll according to initial status */
                   3577:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3578:   /*for(i=1;i<imx;i++) 
                   3579:     printf(" %d\n",s[4][i]);
                   3580:   */
                   3581:   cov[1]=1.;
                   3582: 
                   3583:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3584:   ioffset=0;
                   3585:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3586:     /* ioffset=2+nagesqr+cptcovage; */
                   3587:     ioffset=2+nagesqr;
1.232     brouard  3588:     /* Fixed */
1.224     brouard  3589:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3590:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3591:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3592:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3593: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3594: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3595: /*    cov[2+6]=covar[2][i]; V2  */
                   3596: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3597: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3598: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3599: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3600: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3601: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3602:     }
1.232     brouard  3603:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3604:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3605:     /* } */
1.231     brouard  3606:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3607:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3608:     /* } */
1.225     brouard  3609:     
1.233     brouard  3610: 
                   3611:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3612:     /* Wave varying (but not age varying) */
                   3613:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3614:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3615:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3616:       }
1.232     brouard  3617:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3618:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3619:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3620:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3621:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3622:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3623:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3624:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3625:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3626:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3627:       /* } */
1.126     brouard  3628:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3629:        for (j=1;j<=nlstate+ndeath;j++){
                   3630:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3631:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3632:        }
1.214     brouard  3633:       
                   3634:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3635:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3636:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3637:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3638:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3639:          and mw[mi+1][i]. dh depends on stepm.*/
                   3640:        newm=savm;
1.247     brouard  3641:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3642:        cov[2]=agexact;
                   3643:        if(nagesqr==1)
                   3644:          cov[3]= agexact*agexact;
                   3645:        for (kk=1; kk<=cptcovage;kk++) {
                   3646:          if(!FixedV[Tvar[Tage[kk]]])
                   3647:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3648:          else
                   3649:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3650:        }
                   3651:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3652:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3653:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3654:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3655:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3656:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3657:        savm=oldm;
                   3658:        oldm=newm;
1.126     brouard  3659:       } /* end mult */
                   3660:       
                   3661:       s1=s[mw[mi][i]][i];
                   3662:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3663:       /* if(s2==-1){ */
                   3664:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3665:       /*       /\* exit(1); *\/ */
                   3666:       /* } */
1.126     brouard  3667:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3668:       /* bias is positive if real duration
                   3669:        * is higher than the multiple of stepm and negative otherwise.
                   3670:        */
                   3671:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3672:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3673:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3674:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3675:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3676:        lli= log(survp);
1.126     brouard  3677:       }else if (mle==1){
1.242     brouard  3678:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3679:       } else if(mle==2){
1.242     brouard  3680:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3681:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3682:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3683:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3684:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3685:       } else{  /* mle=0 back to 1 */
1.242     brouard  3686:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3687:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3688:       } /* End of if */
                   3689:       ipmx +=1;
                   3690:       sw += weight[i];
                   3691:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3692:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3693:       if(globpr){
1.246     brouard  3694:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3695:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3696:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3697:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3698:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3699:          llt +=ll[k]*gipmx/gsw;
                   3700:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3701:        }
                   3702:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3703:       }
1.232     brouard  3704:        } /* end of wave */
                   3705: } /* end of individual */
                   3706: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3707: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3708: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3709: if(globpr==0){ /* First time we count the contributions and weights */
                   3710:        gipmx=ipmx;
                   3711:        gsw=sw;
                   3712: }
                   3713: return -l;
1.126     brouard  3714: }
                   3715: 
                   3716: 
                   3717: /*************** function likelione ***********/
                   3718: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3719: {
                   3720:   /* This routine should help understanding what is done with 
                   3721:      the selection of individuals/waves and
                   3722:      to check the exact contribution to the likelihood.
                   3723:      Plotting could be done.
                   3724:    */
                   3725:   int k;
                   3726: 
                   3727:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3728:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3729:     strcat(fileresilk,fileresu);
1.126     brouard  3730:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3731:       printf("Problem with resultfile: %s\n", fileresilk);
                   3732:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3733:     }
1.214     brouard  3734:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3735:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3736:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3737:     for(k=1; k<=nlstate; k++) 
                   3738:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3739:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3740:   }
                   3741: 
                   3742:   *fretone=(*funcone)(p);
                   3743:   if(*globpri !=0){
                   3744:     fclose(ficresilk);
1.205     brouard  3745:     if (mle ==0)
                   3746:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3747:     else if(mle >=1)
                   3748:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3749:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3750:     
1.208     brouard  3751:       
                   3752:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3753:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3754: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3755:     }
1.207     brouard  3756:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3757: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3758:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3759: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3760:     fflush(fichtm);
1.205     brouard  3761:   }
1.126     brouard  3762:   return;
                   3763: }
                   3764: 
                   3765: 
                   3766: /*********** Maximum Likelihood Estimation ***************/
                   3767: 
                   3768: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3769: {
1.165     brouard  3770:   int i,j, iter=0;
1.126     brouard  3771:   double **xi;
                   3772:   double fret;
                   3773:   double fretone; /* Only one call to likelihood */
                   3774:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3775: 
                   3776: #ifdef NLOPT
                   3777:   int creturn;
                   3778:   nlopt_opt opt;
                   3779:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3780:   double *lb;
                   3781:   double minf; /* the minimum objective value, upon return */
                   3782:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3783:   myfunc_data dinst, *d = &dinst;
                   3784: #endif
                   3785: 
                   3786: 
1.126     brouard  3787:   xi=matrix(1,npar,1,npar);
                   3788:   for (i=1;i<=npar;i++)
                   3789:     for (j=1;j<=npar;j++)
                   3790:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3791:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3792:   strcpy(filerespow,"POW_"); 
1.126     brouard  3793:   strcat(filerespow,fileres);
                   3794:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3795:     printf("Problem with resultfile: %s\n", filerespow);
                   3796:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3797:   }
                   3798:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3799:   for (i=1;i<=nlstate;i++)
                   3800:     for(j=1;j<=nlstate+ndeath;j++)
                   3801:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3802:   fprintf(ficrespow,"\n");
1.162     brouard  3803: #ifdef POWELL
1.126     brouard  3804:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3805: #endif
1.126     brouard  3806: 
1.162     brouard  3807: #ifdef NLOPT
                   3808: #ifdef NEWUOA
                   3809:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3810: #else
                   3811:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3812: #endif
                   3813:   lb=vector(0,npar-1);
                   3814:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3815:   nlopt_set_lower_bounds(opt, lb);
                   3816:   nlopt_set_initial_step1(opt, 0.1);
                   3817:   
                   3818:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3819:   d->function = func;
                   3820:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3821:   nlopt_set_min_objective(opt, myfunc, d);
                   3822:   nlopt_set_xtol_rel(opt, ftol);
                   3823:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3824:     printf("nlopt failed! %d\n",creturn); 
                   3825:   }
                   3826:   else {
                   3827:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3828:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3829:     iter=1; /* not equal */
                   3830:   }
                   3831:   nlopt_destroy(opt);
                   3832: #endif
1.126     brouard  3833:   free_matrix(xi,1,npar,1,npar);
                   3834:   fclose(ficrespow);
1.203     brouard  3835:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3836:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3837:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3838: 
                   3839: }
                   3840: 
                   3841: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3842: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3843: {
                   3844:   double  **a,**y,*x,pd;
1.203     brouard  3845:   /* double **hess; */
1.164     brouard  3846:   int i, j;
1.126     brouard  3847:   int *indx;
                   3848: 
                   3849:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3850:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3851:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3852:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3853:   double gompertz(double p[]);
1.203     brouard  3854:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3855: 
                   3856:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3857:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3858:   for (i=1;i<=npar;i++){
1.203     brouard  3859:     printf("%d-",i);fflush(stdout);
                   3860:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3861:    
                   3862:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3863:     
                   3864:     /*  printf(" %f ",p[i]);
                   3865:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3866:   }
                   3867:   
                   3868:   for (i=1;i<=npar;i++) {
                   3869:     for (j=1;j<=npar;j++)  {
                   3870:       if (j>i) { 
1.203     brouard  3871:        printf(".%d-%d",i,j);fflush(stdout);
                   3872:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3873:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3874:        
                   3875:        hess[j][i]=hess[i][j];    
                   3876:        /*printf(" %lf ",hess[i][j]);*/
                   3877:       }
                   3878:     }
                   3879:   }
                   3880:   printf("\n");
                   3881:   fprintf(ficlog,"\n");
                   3882: 
                   3883:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3884:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3885:   
                   3886:   a=matrix(1,npar,1,npar);
                   3887:   y=matrix(1,npar,1,npar);
                   3888:   x=vector(1,npar);
                   3889:   indx=ivector(1,npar);
                   3890:   for (i=1;i<=npar;i++)
                   3891:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3892:   ludcmp(a,npar,indx,&pd);
                   3893: 
                   3894:   for (j=1;j<=npar;j++) {
                   3895:     for (i=1;i<=npar;i++) x[i]=0;
                   3896:     x[j]=1;
                   3897:     lubksb(a,npar,indx,x);
                   3898:     for (i=1;i<=npar;i++){ 
                   3899:       matcov[i][j]=x[i];
                   3900:     }
                   3901:   }
                   3902: 
                   3903:   printf("\n#Hessian matrix#\n");
                   3904:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3905:   for (i=1;i<=npar;i++) { 
                   3906:     for (j=1;j<=npar;j++) { 
1.203     brouard  3907:       printf("%.6e ",hess[i][j]);
                   3908:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3909:     }
                   3910:     printf("\n");
                   3911:     fprintf(ficlog,"\n");
                   3912:   }
                   3913: 
1.203     brouard  3914:   /* printf("\n#Covariance matrix#\n"); */
                   3915:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3916:   /* for (i=1;i<=npar;i++) {  */
                   3917:   /*   for (j=1;j<=npar;j++) {  */
                   3918:   /*     printf("%.6e ",matcov[i][j]); */
                   3919:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3920:   /*   } */
                   3921:   /*   printf("\n"); */
                   3922:   /*   fprintf(ficlog,"\n"); */
                   3923:   /* } */
                   3924: 
1.126     brouard  3925:   /* Recompute Inverse */
1.203     brouard  3926:   /* for (i=1;i<=npar;i++) */
                   3927:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3928:   /* ludcmp(a,npar,indx,&pd); */
                   3929: 
                   3930:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3931: 
                   3932:   /* for (j=1;j<=npar;j++) { */
                   3933:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3934:   /*   x[j]=1; */
                   3935:   /*   lubksb(a,npar,indx,x); */
                   3936:   /*   for (i=1;i<=npar;i++){  */
                   3937:   /*     y[i][j]=x[i]; */
                   3938:   /*     printf("%.3e ",y[i][j]); */
                   3939:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3940:   /*   } */
                   3941:   /*   printf("\n"); */
                   3942:   /*   fprintf(ficlog,"\n"); */
                   3943:   /* } */
                   3944: 
                   3945:   /* Verifying the inverse matrix */
                   3946: #ifdef DEBUGHESS
                   3947:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3948: 
1.203     brouard  3949:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3950:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3951: 
                   3952:   for (j=1;j<=npar;j++) {
                   3953:     for (i=1;i<=npar;i++){ 
1.203     brouard  3954:       printf("%.2f ",y[i][j]);
                   3955:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3956:     }
                   3957:     printf("\n");
                   3958:     fprintf(ficlog,"\n");
                   3959:   }
1.203     brouard  3960: #endif
1.126     brouard  3961: 
                   3962:   free_matrix(a,1,npar,1,npar);
                   3963:   free_matrix(y,1,npar,1,npar);
                   3964:   free_vector(x,1,npar);
                   3965:   free_ivector(indx,1,npar);
1.203     brouard  3966:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3967: 
                   3968: 
                   3969: }
                   3970: 
                   3971: /*************** hessian matrix ****************/
                   3972: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3973: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3974:   int i;
                   3975:   int l=1, lmax=20;
1.203     brouard  3976:   double k1,k2, res, fx;
1.132     brouard  3977:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3978:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3979:   int k=0,kmax=10;
                   3980:   double l1;
                   3981: 
                   3982:   fx=func(x);
                   3983:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3984:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3985:     l1=pow(10,l);
                   3986:     delts=delt;
                   3987:     for(k=1 ; k <kmax; k=k+1){
                   3988:       delt = delta*(l1*k);
                   3989:       p2[theta]=x[theta] +delt;
1.145     brouard  3990:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  3991:       p2[theta]=x[theta]-delt;
                   3992:       k2=func(p2)-fx;
                   3993:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  3994:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  3995:       
1.203     brouard  3996: #ifdef DEBUGHESSII
1.126     brouard  3997:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3998:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   3999: #endif
                   4000:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4001:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4002:        k=kmax;
                   4003:       }
                   4004:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4005:        k=kmax; l=lmax*10;
1.126     brouard  4006:       }
                   4007:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4008:        delts=delt;
                   4009:       }
1.203     brouard  4010:     } /* End loop k */
1.126     brouard  4011:   }
                   4012:   delti[theta]=delts;
                   4013:   return res; 
                   4014:   
                   4015: }
                   4016: 
1.203     brouard  4017: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4018: {
                   4019:   int i;
1.164     brouard  4020:   int l=1, lmax=20;
1.126     brouard  4021:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4022:   double p2[MAXPARM+1];
1.203     brouard  4023:   int k, kmax=1;
                   4024:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4025: 
                   4026:   int firstime=0;
1.203     brouard  4027:   
1.126     brouard  4028:   fx=func(x);
1.203     brouard  4029:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4030:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4031:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4032:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4033:     k1=func(p2)-fx;
                   4034:   
1.203     brouard  4035:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4036:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4037:     k2=func(p2)-fx;
                   4038:   
1.203     brouard  4039:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4040:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4041:     k3=func(p2)-fx;
                   4042:   
1.203     brouard  4043:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4044:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4045:     k4=func(p2)-fx;
1.203     brouard  4046:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4047:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4048:       firstime=1;
1.203     brouard  4049:       kmax=kmax+10;
1.208     brouard  4050:     }
                   4051:     if(kmax >=10 || firstime ==1){
1.246     brouard  4052:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4053:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4054:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4055:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4056:     }
                   4057: #ifdef DEBUGHESSIJ
                   4058:     v1=hess[thetai][thetai];
                   4059:     v2=hess[thetaj][thetaj];
                   4060:     cv12=res;
                   4061:     /* Computing eigen value of Hessian matrix */
                   4062:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4063:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4064:     if ((lc2 <0) || (lc1 <0) ){
                   4065:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4066:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4067:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4068:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4069:     }
1.126     brouard  4070: #endif
                   4071:   }
                   4072:   return res;
                   4073: }
                   4074: 
1.203     brouard  4075:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4076: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4077: /* { */
                   4078: /*   int i; */
                   4079: /*   int l=1, lmax=20; */
                   4080: /*   double k1,k2,k3,k4,res,fx; */
                   4081: /*   double p2[MAXPARM+1]; */
                   4082: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4083: /*   int k=0,kmax=10; */
                   4084: /*   double l1; */
                   4085:   
                   4086: /*   fx=func(x); */
                   4087: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4088: /*     l1=pow(10,l); */
                   4089: /*     delts=delt; */
                   4090: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4091: /*       delt = delti*(l1*k); */
                   4092: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4093: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4094: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4095: /*       k1=func(p2)-fx; */
                   4096:       
                   4097: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4098: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4099: /*       k2=func(p2)-fx; */
                   4100:       
                   4101: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4102: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4103: /*       k3=func(p2)-fx; */
                   4104:       
                   4105: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4106: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4107: /*       k4=func(p2)-fx; */
                   4108: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4109: /* #ifdef DEBUGHESSIJ */
                   4110: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4111: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4112: /* #endif */
                   4113: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4114: /*     k=kmax; */
                   4115: /*       } */
                   4116: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4117: /*     k=kmax; l=lmax*10; */
                   4118: /*       } */
                   4119: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4120: /*     delts=delt; */
                   4121: /*       } */
                   4122: /*     } /\* End loop k *\/ */
                   4123: /*   } */
                   4124: /*   delti[theta]=delts; */
                   4125: /*   return res;  */
                   4126: /* } */
                   4127: 
                   4128: 
1.126     brouard  4129: /************** Inverse of matrix **************/
                   4130: void ludcmp(double **a, int n, int *indx, double *d) 
                   4131: { 
                   4132:   int i,imax,j,k; 
                   4133:   double big,dum,sum,temp; 
                   4134:   double *vv; 
                   4135:  
                   4136:   vv=vector(1,n); 
                   4137:   *d=1.0; 
                   4138:   for (i=1;i<=n;i++) { 
                   4139:     big=0.0; 
                   4140:     for (j=1;j<=n;j++) 
                   4141:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4142:     if (big == 0.0){
                   4143:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4144:       for (j=1;j<=n;j++) {
                   4145:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4146:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4147:       }
                   4148:       fflush(ficlog);
                   4149:       fclose(ficlog);
                   4150:       nrerror("Singular matrix in routine ludcmp"); 
                   4151:     }
1.126     brouard  4152:     vv[i]=1.0/big; 
                   4153:   } 
                   4154:   for (j=1;j<=n;j++) { 
                   4155:     for (i=1;i<j;i++) { 
                   4156:       sum=a[i][j]; 
                   4157:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4158:       a[i][j]=sum; 
                   4159:     } 
                   4160:     big=0.0; 
                   4161:     for (i=j;i<=n;i++) { 
                   4162:       sum=a[i][j]; 
                   4163:       for (k=1;k<j;k++) 
                   4164:        sum -= a[i][k]*a[k][j]; 
                   4165:       a[i][j]=sum; 
                   4166:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4167:        big=dum; 
                   4168:        imax=i; 
                   4169:       } 
                   4170:     } 
                   4171:     if (j != imax) { 
                   4172:       for (k=1;k<=n;k++) { 
                   4173:        dum=a[imax][k]; 
                   4174:        a[imax][k]=a[j][k]; 
                   4175:        a[j][k]=dum; 
                   4176:       } 
                   4177:       *d = -(*d); 
                   4178:       vv[imax]=vv[j]; 
                   4179:     } 
                   4180:     indx[j]=imax; 
                   4181:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4182:     if (j != n) { 
                   4183:       dum=1.0/(a[j][j]); 
                   4184:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4185:     } 
                   4186:   } 
                   4187:   free_vector(vv,1,n);  /* Doesn't work */
                   4188: ;
                   4189: } 
                   4190: 
                   4191: void lubksb(double **a, int n, int *indx, double b[]) 
                   4192: { 
                   4193:   int i,ii=0,ip,j; 
                   4194:   double sum; 
                   4195:  
                   4196:   for (i=1;i<=n;i++) { 
                   4197:     ip=indx[i]; 
                   4198:     sum=b[ip]; 
                   4199:     b[ip]=b[i]; 
                   4200:     if (ii) 
                   4201:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4202:     else if (sum) ii=i; 
                   4203:     b[i]=sum; 
                   4204:   } 
                   4205:   for (i=n;i>=1;i--) { 
                   4206:     sum=b[i]; 
                   4207:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4208:     b[i]=sum/a[i][i]; 
                   4209:   } 
                   4210: } 
                   4211: 
                   4212: void pstamp(FILE *fichier)
                   4213: {
1.196     brouard  4214:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4215: }
                   4216: 
1.253     brouard  4217: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4218: 
                   4219:   /* y=a+bx regression */
                   4220:   double   sumx = 0.0;                        /* sum of x                      */
                   4221:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4222:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4223:   double   sumy = 0.0;                        /* sum of y                      */
                   4224:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4225:   double   sume2; /* sum of square or residuals */
                   4226:   double yhat;
                   4227:   
                   4228:   double denom=0;
                   4229:   int i;
                   4230:   int ne=*no;
                   4231:   
                   4232:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4233:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4234:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4235:       continue;
                   4236:     }
                   4237:     ne=ne+1;
                   4238:     sumx  += x[i];       
                   4239:     sumx2 += x[i]*x[i];  
                   4240:     sumxy += x[i] * y[i];
                   4241:     sumy  += y[i];      
                   4242:     sumy2 += y[i]*y[i]; 
                   4243:     denom = (ne * sumx2 - sumx*sumx);
                   4244:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4245:   } 
                   4246:   
                   4247:   denom = (ne * sumx2 - sumx*sumx);
                   4248:   if (denom == 0) {
                   4249:     // vertical, slope m is infinity
                   4250:     *b = INFINITY;
                   4251:     *a = 0;
                   4252:     if (r) *r = 0;
                   4253:     return 1;
                   4254:   }
                   4255:   
                   4256:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4257:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4258:   if (r!=NULL) {
                   4259:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4260:       sqrt((sumx2 - sumx*sumx/ne) *
                   4261:           (sumy2 - sumy*sumy/ne));
                   4262:   }
                   4263:   *no=ne;
                   4264:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4265:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4266:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4267:       continue;
                   4268:     }
                   4269:     ne=ne+1;
                   4270:     yhat = y[i] - *a -*b* x[i];
                   4271:     sume2  += yhat * yhat ;       
                   4272:     
                   4273:     denom = (ne * sumx2 - sumx*sumx);
                   4274:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4275:   } 
                   4276:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4277:   *sa= *sb * sqrt(sumx2/ne);
                   4278:   
                   4279:   return 0; 
                   4280: }
                   4281: 
1.126     brouard  4282: /************ Frequencies ********************/
1.251     brouard  4283: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4284:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4285:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4286: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4287:   
1.253     brouard  4288:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4289:   int iind=0, iage=0;
                   4290:   int mi; /* Effective wave */
                   4291:   int first;
                   4292:   double ***freq; /* Frequencies */
1.253     brouard  4293:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4294:   int no;
1.226     brouard  4295:   double *meanq;
                   4296:   double **meanqt;
                   4297:   double *pp, **prop, *posprop, *pospropt;
                   4298:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4299:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4300:   double agebegin, ageend;
                   4301:     
                   4302:   pp=vector(1,nlstate);
1.251     brouard  4303:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4304:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4305:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4306:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4307:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4308:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4309:   strcpy(fileresp,"P_");
                   4310:   strcat(fileresp,fileresu);
                   4311:   /*strcat(fileresphtm,fileresu);*/
                   4312:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4313:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4314:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4315:     exit(0);
                   4316:   }
1.240     brouard  4317:   
1.226     brouard  4318:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4319:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4320:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4321:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4322:     fflush(ficlog);
                   4323:     exit(70); 
                   4324:   }
                   4325:   else{
                   4326:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4327: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4328: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4329:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4330:   }
1.237     brouard  4331:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4332:   
1.226     brouard  4333:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4334:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4335:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4336:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4337:     fflush(ficlog);
                   4338:     exit(70); 
1.240     brouard  4339:   } else{
1.226     brouard  4340:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4341: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4342: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4343:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4344:   }
1.240     brouard  4345:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4346:   
1.253     brouard  4347:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4348:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4349:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4350:   j1=0;
1.126     brouard  4351:   
1.227     brouard  4352:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4353:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4354:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4355:   
                   4356:   
1.226     brouard  4357:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4358:      reference=low_education V1=0,V2=0
                   4359:      med_educ                V1=1 V2=0, 
                   4360:      high_educ               V1=0 V2=1
                   4361:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4362:   */
1.249     brouard  4363:   dateintsum=0;
                   4364:   k2cpt=0;
                   4365: 
1.253     brouard  4366:   if(cptcoveff == 0 )
                   4367:     nl=1;  /* Constant model only */
                   4368:   else
                   4369:     nl=2;
                   4370:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4371:     if(nj==1)
                   4372:       j=0;  /* First pass for the constant */
                   4373:     else
                   4374:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4375:     first=1;
                   4376:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4377:       posproptt=0.;
                   4378:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4379:        scanf("%d", i);*/
                   4380:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4381:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4382:          for(m=iagemin; m <= iagemax+3; m++)
                   4383:            freq[i][jk][m]=0;
                   4384:       
                   4385:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4386:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4387:          prop[i][m]=0;
                   4388:        posprop[i]=0;
                   4389:        pospropt[i]=0;
                   4390:       }
                   4391:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4392:       /*   meanq[z1]+=0.; */
                   4393:       /*   for(m=1;m<=lastpass;m++){ */
                   4394:       /*       meanqt[m][z1]=0.; */
                   4395:       /*   } */
                   4396:       /* } */
                   4397:       
                   4398:       /* dateintsum=0; */
                   4399:       /* k2cpt=0; */
                   4400:       
                   4401:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4402:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4403:        bool=1;
                   4404:        if(j !=0){
                   4405:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4406:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4407:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4408:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4409:              /* } */
                   4410:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4411:                /* if(Tvaraff[z1] ==-20){ */
                   4412:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4413:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4414:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4415:                /* }else  */
                   4416:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4417:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4418:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4419:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4420:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4421:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4422:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4423:                } /* Onlyf fixed */
                   4424:              } /* end z1 */
                   4425:            } /* cptcovn > 0 */
                   4426:          } /* end any */
                   4427:        }/* end j==0 */
                   4428:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4429:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4430:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4431:            m=mw[mi][iind];
                   4432:            if(j!=0){
                   4433:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4434:                for (z1=1; z1<=cptcoveff; z1++) {
                   4435:                  if( Fixed[Tmodelind[z1]]==1){
                   4436:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4437:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4438:                                                                                      value is -1, we don't select. It differs from the 
                   4439:                                                                                      constant and age model which counts them. */
                   4440:                      bool=0; /* not selected */
                   4441:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4442:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4443:                      bool=0;
                   4444:                    }
                   4445:                  }
                   4446:                }
                   4447:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4448:            } /* end j==0 */
                   4449:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4450:            if(bool==1){
                   4451:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4452:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4453:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4454:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4455:              if(m >=firstpass && m <=lastpass){
                   4456:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4457:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4458:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4459:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4460:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4461:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4462:                if (m<lastpass) {
                   4463:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4464:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4465:                  if(s[m][iind]==-1)
                   4466:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4467:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4468:                  /* if((int)agev[m][iind] == 55) */
                   4469:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4470:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4471:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4472:                }
1.251     brouard  4473:              } /* end if between passes */  
                   4474:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4475:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4476:                k2cpt++;
                   4477:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4478:              }
1.251     brouard  4479:            }else{
                   4480:              bool=1;
                   4481:            }/* end bool 2 */
                   4482:          } /* end m */
                   4483:        } /* end bool */
                   4484:       } /* end iind = 1 to imx */
                   4485:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4486:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4487:       
                   4488:       
                   4489:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4490:       pstamp(ficresp);
                   4491:       if  (cptcoveff>0 && j!=0){
                   4492:        printf( "\n#********** Variable "); 
                   4493:        fprintf(ficresp, "\n#********** Variable "); 
                   4494:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4495:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4496:        fprintf(ficlog, "\n#********** Variable "); 
                   4497:        for (z1=1; z1<=cptcoveff; z1++){
                   4498:          if(!FixedV[Tvaraff[z1]]){
                   4499:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4500:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4501:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4502:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4503:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4504:          }else{
1.251     brouard  4505:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4506:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4507:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4508:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4509:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4510:          }
                   4511:        }
                   4512:        printf( "**********\n#");
                   4513:        fprintf(ficresp, "**********\n#");
                   4514:        fprintf(ficresphtm, "**********</h3>\n");
                   4515:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4516:        fprintf(ficlog, "**********\n");
                   4517:       }
                   4518:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4519:       for(i=1; i<=nlstate;i++) {
                   4520:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4521:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4522:       }
                   4523:       fprintf(ficresp, "\n");
                   4524:       fprintf(ficresphtm, "\n");
                   4525:       
                   4526:       /* Header of frequency table by age */
                   4527:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4528:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4529:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4530:        for(m=-1; m <=nlstate+ndeath; m++){
                   4531:          if(jk!=0 && m!=0)
                   4532:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4533:        }
1.226     brouard  4534:       }
1.251     brouard  4535:       fprintf(ficresphtmfr, "\n");
                   4536:     
                   4537:       /* For each age */
                   4538:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4539:        fprintf(ficresphtm,"<tr>");
                   4540:        if(iage==iagemax+1){
                   4541:          fprintf(ficlog,"1");
                   4542:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4543:        }else if(iage==iagemax+2){
                   4544:          fprintf(ficlog,"0");
                   4545:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4546:        }else if(iage==iagemax+3){
                   4547:          fprintf(ficlog,"Total");
                   4548:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4549:        }else{
1.240     brouard  4550:          if(first==1){
1.251     brouard  4551:            first=0;
                   4552:            printf("See log file for details...\n");
                   4553:          }
                   4554:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4555:          fprintf(ficlog,"Age %d", iage);
                   4556:        }
                   4557:        for(jk=1; jk <=nlstate ; jk++){
                   4558:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4559:            pp[jk] += freq[jk][m][iage]; 
                   4560:        }
                   4561:        for(jk=1; jk <=nlstate ; jk++){
                   4562:          for(m=-1, pos=0; m <=0 ; m++)
                   4563:            pos += freq[jk][m][iage];
                   4564:          if(pp[jk]>=1.e-10){
                   4565:            if(first==1){
                   4566:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4567:            }
                   4568:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4569:          }else{
                   4570:            if(first==1)
                   4571:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4572:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4573:          }
                   4574:        }
                   4575:       
1.251     brouard  4576:        for(jk=1; jk <=nlstate ; jk++){ 
                   4577:          /* posprop[jk]=0; */
                   4578:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4579:            pp[jk] += freq[jk][m][iage];
                   4580:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4581:       
                   4582:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4583:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4584:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4585:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4586:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4587:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4588:        }
1.251     brouard  4589:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4590:          if(pos>=1.e-5){
1.251     brouard  4591:            if(first==1)
                   4592:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4593:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4594:          }else{
                   4595:            if(first==1)
                   4596:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4597:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4598:          }
                   4599:          if( iage <= iagemax){
                   4600:            if(pos>=1.e-5){
                   4601:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4602:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4603:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4604:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4605:            }
                   4606:            else{
                   4607:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4608:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4609:            }
1.240     brouard  4610:          }
1.251     brouard  4611:          pospropt[jk] +=posprop[jk];
                   4612:        } /* end loop jk */
                   4613:        /* pospropt=0.; */
                   4614:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4615:          for(m=-1; m <=nlstate+ndeath; m++){
                   4616:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4617:              if(first==1){
                   4618:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4619:              }
1.253     brouard  4620:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4621:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4622:            }
                   4623:            if(jk!=0 && m!=0)
                   4624:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4625:          }
1.251     brouard  4626:        } /* end loop jk */
                   4627:        posproptt=0.; 
                   4628:        for(jk=1; jk <=nlstate; jk++){
                   4629:          posproptt += pospropt[jk];
                   4630:        }
                   4631:        fprintf(ficresphtmfr,"</tr>\n ");
                   4632:        if(iage <= iagemax){
                   4633:          fprintf(ficresp,"\n");
                   4634:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4635:        }
1.251     brouard  4636:        if(first==1)
                   4637:          printf("Others in log...\n");
                   4638:        fprintf(ficlog,"\n");
                   4639:       } /* end loop age iage */
                   4640:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4641:       for(jk=1; jk <=nlstate ; jk++){
                   4642:        if(posproptt < 1.e-5){
                   4643:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4644:        }else{
                   4645:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4646:        }
1.226     brouard  4647:       }
1.251     brouard  4648:       fprintf(ficresphtm,"</tr>\n");
                   4649:       fprintf(ficresphtm,"</table>\n");
                   4650:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4651:       if(posproptt < 1.e-5){
1.251     brouard  4652:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4653:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4654:        fprintf(ficres,"\n  This combination (%d) is not valid and no result will be produced\n\n",j1);
                   4655:        invalidvarcomb[j1]=1;
1.226     brouard  4656:       }else{
1.251     brouard  4657:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4658:        invalidvarcomb[j1]=0;
1.226     brouard  4659:       }
1.251     brouard  4660:       fprintf(ficresphtmfr,"</table>\n");
                   4661:       fprintf(ficlog,"\n");
                   4662:       if(j!=0){
                   4663:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4664:        for(i=1,jk=1; i <=nlstate; i++){
                   4665:          for(k=1; k <=(nlstate+ndeath); k++){
                   4666:            if (k != i) {
                   4667:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4668:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4669:                  if(j1==1){ /* All dummy covariates to zero */
                   4670:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4671:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4672:                    printf("%d%d ",i,k);
                   4673:                    fprintf(ficlog,"%d%d ",i,k);
                   4674:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4675:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4676:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4677:                  }
1.253     brouard  4678:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4679:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4680:                    x[iage]= (double)iage;
                   4681:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4682:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4683:                  }
                   4684:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4685:                  pstart[jk]=b;
                   4686:                  pstart[jk-1]=a;
1.252     brouard  4687:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4688:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4689:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4690:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4691:                  printf("%d%d ",i,k);
                   4692:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4693:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4694:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4695:                  ;
                   4696:                }
                   4697:                /* printf("%12.7f )", param[i][jj][k]); */
                   4698:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4699:                jk++; 
                   4700:              } /* end jj */
                   4701:            } /* end k!= i */
                   4702:          } /* end k */
                   4703:        } /* end i, jk */
                   4704:       } /* end j !=0 */
                   4705:     } /* end selected combination of covariate j1 */
                   4706:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4707:       printf("#Freqsummary: Starting values for the constants:\n");
                   4708:       fprintf(ficlog,"\n");
                   4709:       for(i=1,jk=1; i <=nlstate; i++){
                   4710:        for(k=1; k <=(nlstate+ndeath); k++){
                   4711:          if (k != i) {
                   4712:            printf("%d%d ",i,k);
                   4713:            fprintf(ficlog,"%d%d ",i,k);
                   4714:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4715:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4716:              if(jj==1){ /* Age has to be done */
                   4717:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4718:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4719:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4720:              }
                   4721:              /* printf("%12.7f )", param[i][jj][k]); */
                   4722:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4723:              jk++; 
1.250     brouard  4724:            }
1.251     brouard  4725:            printf("\n");
                   4726:            fprintf(ficlog,"\n");
1.250     brouard  4727:          }
                   4728:        }
                   4729:       }
1.251     brouard  4730:       printf("#Freqsummary\n");
                   4731:       fprintf(ficlog,"\n");
                   4732:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4733:        for(m=-1; m <=nlstate+ndeath; m++){
                   4734:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4735:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4736:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4737:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4738:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4739:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4740:          /* } */
                   4741:        }
                   4742:       } /* end loop jk */
                   4743:       
                   4744:       printf("\n");
                   4745:       fprintf(ficlog,"\n");
                   4746:     } /* end j=0 */
1.249     brouard  4747:   } /* end j */
1.252     brouard  4748: 
1.253     brouard  4749:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4750:     for(i=1, jk=1; i <=nlstate; i++){
                   4751:       for(j=1; j <=nlstate+ndeath; j++){
                   4752:        if(j!=i){
                   4753:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4754:          printf("%1d%1d",i,j);
                   4755:          fprintf(ficparo,"%1d%1d",i,j);
                   4756:          for(k=1; k<=ncovmodel;k++){
                   4757:            /*    printf(" %lf",param[i][j][k]); */
                   4758:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4759:            p[jk]=pstart[jk];
                   4760:            printf(" %f ",pstart[jk]);
                   4761:            fprintf(ficparo," %f ",pstart[jk]);
                   4762:            jk++;
                   4763:          }
                   4764:          printf("\n");
                   4765:          fprintf(ficparo,"\n");
                   4766:        }
                   4767:       }
                   4768:     }
                   4769:   } /* end mle=-2 */
1.226     brouard  4770:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4771:   
1.226     brouard  4772:   fclose(ficresp);
                   4773:   fclose(ficresphtm);
                   4774:   fclose(ficresphtmfr);
                   4775:   free_vector(meanq,1,nqfveff);
                   4776:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4777:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4778:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4779:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4780:   free_vector(pospropt,1,nlstate);
                   4781:   free_vector(posprop,1,nlstate);
1.251     brouard  4782:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4783:   free_vector(pp,1,nlstate);
                   4784:   /* End of freqsummary */
                   4785: }
1.126     brouard  4786: 
                   4787: /************ Prevalence ********************/
1.227     brouard  4788: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4789: {  
                   4790:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4791:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4792:      We still use firstpass and lastpass as another selection.
                   4793:   */
1.126     brouard  4794:  
1.227     brouard  4795:   int i, m, jk, j1, bool, z1,j, iv;
                   4796:   int mi; /* Effective wave */
                   4797:   int iage;
                   4798:   double agebegin, ageend;
                   4799: 
                   4800:   double **prop;
                   4801:   double posprop; 
                   4802:   double  y2; /* in fractional years */
                   4803:   int iagemin, iagemax;
                   4804:   int first; /** to stop verbosity which is redirected to log file */
                   4805: 
                   4806:   iagemin= (int) agemin;
                   4807:   iagemax= (int) agemax;
                   4808:   /*pp=vector(1,nlstate);*/
1.251     brouard  4809:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4810:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4811:   j1=0;
1.222     brouard  4812:   
1.227     brouard  4813:   /*j=cptcoveff;*/
                   4814:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4815:   
1.227     brouard  4816:   first=1;
                   4817:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4818:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4819:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4820:        prop[i][iage]=0.0;
                   4821:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4822:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4823:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4824:     
                   4825:     for (i=1; i<=imx; i++) { /* Each individual */
                   4826:       bool=1;
                   4827:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4828:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4829:        m=mw[mi][i];
                   4830:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4831:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4832:        for (z1=1; z1<=cptcoveff; z1++){
                   4833:          if( Fixed[Tmodelind[z1]]==1){
                   4834:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4835:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4836:              bool=0;
                   4837:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4838:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4839:              bool=0;
                   4840:            }
                   4841:        }
                   4842:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4843:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4844:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4845:          if(m >=firstpass && m <=lastpass){
                   4846:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4847:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4848:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4849:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4850:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4851:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4852:                exit(1);
                   4853:              }
                   4854:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4855:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4856:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4857:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4858:              } /* end valid statuses */ 
                   4859:            } /* end selection of dates */
                   4860:          } /* end selection of waves */
                   4861:        } /* end bool */
                   4862:       } /* end wave */
                   4863:     } /* end individual */
                   4864:     for(i=iagemin; i <= iagemax+3; i++){  
                   4865:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4866:        posprop += prop[jk][i]; 
                   4867:       } 
                   4868:       
                   4869:       for(jk=1; jk <=nlstate ; jk++){      
                   4870:        if( i <=  iagemax){ 
                   4871:          if(posprop>=1.e-5){ 
                   4872:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4873:          } else{
                   4874:            if(first==1){
                   4875:              first=0;
                   4876:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4877:            }
                   4878:          }
                   4879:        } 
                   4880:       }/* end jk */ 
                   4881:     }/* end i */ 
1.222     brouard  4882:      /*} *//* end i1 */
1.227     brouard  4883:   } /* end j1 */
1.222     brouard  4884:   
1.227     brouard  4885:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4886:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4887:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4888: }  /* End of prevalence */
1.126     brouard  4889: 
                   4890: /************* Waves Concatenation ***************/
                   4891: 
                   4892: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4893: {
                   4894:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4895:      Death is a valid wave (if date is known).
                   4896:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4897:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4898:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4899:   */
1.126     brouard  4900: 
1.224     brouard  4901:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4902:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4903:      double sum=0., jmean=0.;*/
1.224     brouard  4904:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4905:   int j, k=0,jk, ju, jl;
                   4906:   double sum=0.;
                   4907:   first=0;
1.214     brouard  4908:   firstwo=0;
1.217     brouard  4909:   firsthree=0;
1.218     brouard  4910:   firstfour=0;
1.164     brouard  4911:   jmin=100000;
1.126     brouard  4912:   jmax=-1;
                   4913:   jmean=0.;
1.224     brouard  4914: 
                   4915: /* Treating live states */
1.214     brouard  4916:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4917:     mi=0;  /* First valid wave */
1.227     brouard  4918:     mli=0; /* Last valid wave */
1.126     brouard  4919:     m=firstpass;
1.214     brouard  4920:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4921:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4922:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4923:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4924:        mw[++mi][i]=m;
                   4925:        mli=m;
1.224     brouard  4926:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4927:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4928:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4929:       }
1.227     brouard  4930:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4931: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4932:        break;
1.224     brouard  4933: #else
1.227     brouard  4934:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4935:          if(firsthree == 0){
                   4936:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4937:            firsthree=1;
                   4938:          }
                   4939:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4940:          mw[++mi][i]=m;
                   4941:          mli=m;
                   4942:        }
                   4943:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4944:          nbwarn++;
                   4945:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4946:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4947:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4948:          }
                   4949:          break;
                   4950:        }
                   4951:        break;
1.224     brouard  4952: #endif
1.227     brouard  4953:       }/* End m >= lastpass */
1.126     brouard  4954:     }/* end while */
1.224     brouard  4955: 
1.227     brouard  4956:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4957:     /* After last pass */
1.224     brouard  4958: /* Treating death states */
1.214     brouard  4959:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4960:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4961:       /* } */
1.126     brouard  4962:       mi++;    /* Death is another wave */
                   4963:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4964:       /* Only death is a correct wave */
1.126     brouard  4965:       mw[mi][i]=m;
1.257     brouard  4966:     } /* else not in a death state */
1.224     brouard  4967: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  4968:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  4969:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4970:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4971:          nbwarn++;
                   4972:          if(firstfiv==0){
                   4973:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4974:            firstfiv=1;
                   4975:          }else{
                   4976:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4977:          }
                   4978:        }else{ /* Death occured afer last wave potential bias */
                   4979:          nberr++;
                   4980:          if(firstwo==0){
1.257     brouard  4981:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  4982:            firstwo=1;
                   4983:          }
1.257     brouard  4984:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  4985:        }
1.257     brouard  4986:       }else{ /* if date of interview is unknown */
1.227     brouard  4987:        /* death is known but not confirmed by death status at any wave */
                   4988:        if(firstfour==0){
                   4989:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   4990:          firstfour=1;
                   4991:        }
                   4992:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  4993:       }
1.224     brouard  4994:     } /* end if date of death is known */
                   4995: #endif
                   4996:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   4997:     /* wav[i]=mw[mi][i]; */
1.126     brouard  4998:     if(mi==0){
                   4999:       nbwarn++;
                   5000:       if(first==0){
1.227     brouard  5001:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5002:        first=1;
1.126     brouard  5003:       }
                   5004:       if(first==1){
1.227     brouard  5005:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5006:       }
                   5007:     } /* end mi==0 */
                   5008:   } /* End individuals */
1.214     brouard  5009:   /* wav and mw are no more changed */
1.223     brouard  5010:        
1.214     brouard  5011:   
1.126     brouard  5012:   for(i=1; i<=imx; i++){
                   5013:     for(mi=1; mi<wav[i];mi++){
                   5014:       if (stepm <=0)
1.227     brouard  5015:        dh[mi][i]=1;
1.126     brouard  5016:       else{
1.227     brouard  5017:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
                   5018:          if (agedc[i] < 2*AGESUP) {
                   5019:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5020:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5021:            else if(j<0){
                   5022:              nberr++;
                   5023:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5024:              j=1; /* Temporary Dangerous patch */
                   5025:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5026:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5027:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5028:            }
                   5029:            k=k+1;
                   5030:            if (j >= jmax){
                   5031:              jmax=j;
                   5032:              ijmax=i;
                   5033:            }
                   5034:            if (j <= jmin){
                   5035:              jmin=j;
                   5036:              ijmin=i;
                   5037:            }
                   5038:            sum=sum+j;
                   5039:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5040:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5041:          }
                   5042:        }
                   5043:        else{
                   5044:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5045: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5046:                                        
1.227     brouard  5047:          k=k+1;
                   5048:          if (j >= jmax) {
                   5049:            jmax=j;
                   5050:            ijmax=i;
                   5051:          }
                   5052:          else if (j <= jmin){
                   5053:            jmin=j;
                   5054:            ijmin=i;
                   5055:          }
                   5056:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5057:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5058:          if(j<0){
                   5059:            nberr++;
                   5060:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5061:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5062:          }
                   5063:          sum=sum+j;
                   5064:        }
                   5065:        jk= j/stepm;
                   5066:        jl= j -jk*stepm;
                   5067:        ju= j -(jk+1)*stepm;
                   5068:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5069:          if(jl==0){
                   5070:            dh[mi][i]=jk;
                   5071:            bh[mi][i]=0;
                   5072:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5073:                  * to avoid the price of an extra matrix product in likelihood */
                   5074:            dh[mi][i]=jk+1;
                   5075:            bh[mi][i]=ju;
                   5076:          }
                   5077:        }else{
                   5078:          if(jl <= -ju){
                   5079:            dh[mi][i]=jk;
                   5080:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5081:                                 * is higher than the multiple of stepm and negative otherwise.
                   5082:                                 */
                   5083:          }
                   5084:          else{
                   5085:            dh[mi][i]=jk+1;
                   5086:            bh[mi][i]=ju;
                   5087:          }
                   5088:          if(dh[mi][i]==0){
                   5089:            dh[mi][i]=1; /* At least one step */
                   5090:            bh[mi][i]=ju; /* At least one step */
                   5091:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5092:          }
                   5093:        } /* end if mle */
1.126     brouard  5094:       }
                   5095:     } /* end wave */
                   5096:   }
                   5097:   jmean=sum/k;
                   5098:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5099:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5100: }
1.126     brouard  5101: 
                   5102: /*********** Tricode ****************************/
1.220     brouard  5103:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5104:  {
                   5105:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5106:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5107:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5108:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5109:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5110:     */
1.130     brouard  5111: 
1.242     brouard  5112:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5113:    int modmaxcovj=0; /* Modality max of covariates j */
                   5114:    int cptcode=0; /* Modality max of covariates j */
                   5115:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5116: 
                   5117: 
1.242     brouard  5118:    /* cptcoveff=0;  */
                   5119:    /* *cptcov=0; */
1.126     brouard  5120:  
1.242     brouard  5121:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5122: 
1.242     brouard  5123:    /* Loop on covariates without age and products and no quantitative variable */
                   5124:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5125:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5126:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5127:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5128:        switch(Fixed[k]) {
                   5129:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5130:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5131:           ij=(int)(covar[Tvar[k]][i]);
                   5132:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5133:            * If product of Vn*Vm, still boolean *:
                   5134:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5135:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5136:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5137:              modality of the nth covariate of individual i. */
                   5138:           if (ij > modmaxcovj)
                   5139:             modmaxcovj=ij; 
                   5140:           else if (ij < modmincovj) 
                   5141:             modmincovj=ij; 
                   5142:           if ((ij < -1) && (ij > NCOVMAX)){
                   5143:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5144:             exit(1);
                   5145:           }else
                   5146:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5147:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5148:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5149:           /* getting the maximum value of the modality of the covariate
                   5150:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5151:              female ies 1, then modmaxcovj=1.
                   5152:           */
                   5153:         } /* end for loop on individuals i */
                   5154:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5155:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5156:         cptcode=modmaxcovj;
                   5157:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5158:         /*for (i=0; i<=cptcode; i++) {*/
                   5159:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5160:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5161:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5162:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5163:             if( j != -1){
                   5164:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5165:                                  covariate for which somebody answered excluding 
                   5166:                                  undefined. Usually 2: 0 and 1. */
                   5167:             }
                   5168:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5169:                                     covariate for which somebody answered including 
                   5170:                                     undefined. Usually 3: -1, 0 and 1. */
                   5171:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5172:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5173:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5174:                        
1.242     brouard  5175:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5176:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5177:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5178:         /* modmincovj=3; modmaxcovj = 7; */
                   5179:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5180:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5181:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5182:         /* nbcode[Tvar[j]][ij]=k; */
                   5183:         /* nbcode[Tvar[j]][1]=0; */
                   5184:         /* nbcode[Tvar[j]][2]=1; */
                   5185:         /* nbcode[Tvar[j]][3]=2; */
                   5186:         /* To be continued (not working yet). */
                   5187:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5188:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5189:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5190:             break;
                   5191:           }
                   5192:           ij++;
                   5193:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5194:           cptcode = ij; /* New max modality for covar j */
                   5195:         } /* end of loop on modality i=-1 to 1 or more */
                   5196:         break;
                   5197:        case 1: /* Testing on varying covariate, could be simple and
                   5198:                * should look at waves or product of fixed *
                   5199:                * varying. No time to test -1, assuming 0 and 1 only */
                   5200:         ij=0;
                   5201:         for(i=0; i<=1;i++){
                   5202:           nbcode[Tvar[k]][++ij]=i;
                   5203:         }
                   5204:         break;
                   5205:        default:
                   5206:         break;
                   5207:        } /* end switch */
                   5208:      } /* end dummy test */
                   5209:     
                   5210:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5211:      /*        /\*recode from 0 *\/ */
                   5212:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5213:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5214:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5215:      /*        } */
                   5216:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5217:      /*        if (ij > ncodemax[j]) { */
                   5218:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5219:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5220:      /*          break; */
                   5221:      /*        } */
                   5222:      /*   }  /\* end of loop on modality k *\/ */
                   5223:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5224:   
                   5225:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5226:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5227:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5228:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5229:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5230:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5231:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5232:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5233:   
                   5234:    ij=0;
                   5235:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5236:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5237:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5238:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5239:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5240:        /* If product not in single variable we don't print results */
                   5241:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5242:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5243:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5244:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5245:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5246:        if(Fixed[k]!=0)
                   5247:         anyvaryingduminmodel=1;
                   5248:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5249:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5250:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5251:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5252:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5253:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5254:      } 
                   5255:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5256:    /* ij--; */
                   5257:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5258:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5259:                * because they can be excluded from the model and real
                   5260:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5261:    for(j=ij+1; j<= cptcovt; j++){
                   5262:      Tvaraff[j]=0;
                   5263:      Tmodelind[j]=0;
                   5264:    }
                   5265:    for(j=ntveff+1; j<= cptcovt; j++){
                   5266:      TmodelInvind[j]=0;
                   5267:    }
                   5268:    /* To be sorted */
                   5269:    ;
                   5270:  }
1.126     brouard  5271: 
1.145     brouard  5272: 
1.126     brouard  5273: /*********** Health Expectancies ****************/
                   5274: 
1.235     brouard  5275:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5276: 
                   5277: {
                   5278:   /* Health expectancies, no variances */
1.164     brouard  5279:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5280:   int nhstepma, nstepma; /* Decreasing with age */
                   5281:   double age, agelim, hf;
                   5282:   double ***p3mat;
                   5283:   double eip;
                   5284: 
1.238     brouard  5285:   /* pstamp(ficreseij); */
1.126     brouard  5286:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5287:   fprintf(ficreseij,"# Age");
                   5288:   for(i=1; i<=nlstate;i++){
                   5289:     for(j=1; j<=nlstate;j++){
                   5290:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5291:     }
                   5292:     fprintf(ficreseij," e%1d. ",i);
                   5293:   }
                   5294:   fprintf(ficreseij,"\n");
                   5295: 
                   5296:   
                   5297:   if(estepm < stepm){
                   5298:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5299:   }
                   5300:   else  hstepm=estepm;   
                   5301:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5302:    * This is mainly to measure the difference between two models: for example
                   5303:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5304:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5305:    * progression in between and thus overestimating or underestimating according
                   5306:    * to the curvature of the survival function. If, for the same date, we 
                   5307:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5308:    * to compare the new estimate of Life expectancy with the same linear 
                   5309:    * hypothesis. A more precise result, taking into account a more precise
                   5310:    * curvature will be obtained if estepm is as small as stepm. */
                   5311: 
                   5312:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5313:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5314:      nhstepm is the number of hstepm from age to agelim 
                   5315:      nstepm is the number of stepm from age to agelin. 
                   5316:      Look at hpijx to understand the reason of that which relies in memory size
                   5317:      and note for a fixed period like estepm months */
                   5318:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5319:      survival function given by stepm (the optimization length). Unfortunately it
                   5320:      means that if the survival funtion is printed only each two years of age and if
                   5321:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5322:      results. So we changed our mind and took the option of the best precision.
                   5323:   */
                   5324:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5325: 
                   5326:   agelim=AGESUP;
                   5327:   /* If stepm=6 months */
                   5328:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5329:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5330:     
                   5331: /* nhstepm age range expressed in number of stepm */
                   5332:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5333:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5334:   /* if (stepm >= YEARM) hstepm=1;*/
                   5335:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5336:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5337: 
                   5338:   for (age=bage; age<=fage; age ++){ 
                   5339:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5340:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5341:     /* if (stepm >= YEARM) hstepm=1;*/
                   5342:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5343: 
                   5344:     /* If stepm=6 months */
                   5345:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5346:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5347:     
1.235     brouard  5348:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5349:     
                   5350:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5351:     
                   5352:     printf("%d|",(int)age);fflush(stdout);
                   5353:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5354:     
                   5355:     /* Computing expectancies */
                   5356:     for(i=1; i<=nlstate;i++)
                   5357:       for(j=1; j<=nlstate;j++)
                   5358:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5359:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5360:          
                   5361:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5362: 
                   5363:        }
                   5364: 
                   5365:     fprintf(ficreseij,"%3.0f",age );
                   5366:     for(i=1; i<=nlstate;i++){
                   5367:       eip=0;
                   5368:       for(j=1; j<=nlstate;j++){
                   5369:        eip +=eij[i][j][(int)age];
                   5370:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5371:       }
                   5372:       fprintf(ficreseij,"%9.4f", eip );
                   5373:     }
                   5374:     fprintf(ficreseij,"\n");
                   5375:     
                   5376:   }
                   5377:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5378:   printf("\n");
                   5379:   fprintf(ficlog,"\n");
                   5380:   
                   5381: }
                   5382: 
1.235     brouard  5383:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5384: 
                   5385: {
                   5386:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5387:      to initial status i, ei. .
1.126     brouard  5388:   */
                   5389:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5390:   int nhstepma, nstepma; /* Decreasing with age */
                   5391:   double age, agelim, hf;
                   5392:   double ***p3matp, ***p3matm, ***varhe;
                   5393:   double **dnewm,**doldm;
                   5394:   double *xp, *xm;
                   5395:   double **gp, **gm;
                   5396:   double ***gradg, ***trgradg;
                   5397:   int theta;
                   5398: 
                   5399:   double eip, vip;
                   5400: 
                   5401:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5402:   xp=vector(1,npar);
                   5403:   xm=vector(1,npar);
                   5404:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5405:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5406:   
                   5407:   pstamp(ficresstdeij);
                   5408:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5409:   fprintf(ficresstdeij,"# Age");
                   5410:   for(i=1; i<=nlstate;i++){
                   5411:     for(j=1; j<=nlstate;j++)
                   5412:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5413:     fprintf(ficresstdeij," e%1d. ",i);
                   5414:   }
                   5415:   fprintf(ficresstdeij,"\n");
                   5416: 
                   5417:   pstamp(ficrescveij);
                   5418:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5419:   fprintf(ficrescveij,"# Age");
                   5420:   for(i=1; i<=nlstate;i++)
                   5421:     for(j=1; j<=nlstate;j++){
                   5422:       cptj= (j-1)*nlstate+i;
                   5423:       for(i2=1; i2<=nlstate;i2++)
                   5424:        for(j2=1; j2<=nlstate;j2++){
                   5425:          cptj2= (j2-1)*nlstate+i2;
                   5426:          if(cptj2 <= cptj)
                   5427:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5428:        }
                   5429:     }
                   5430:   fprintf(ficrescveij,"\n");
                   5431:   
                   5432:   if(estepm < stepm){
                   5433:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5434:   }
                   5435:   else  hstepm=estepm;   
                   5436:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5437:    * This is mainly to measure the difference between two models: for example
                   5438:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5439:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5440:    * progression in between and thus overestimating or underestimating according
                   5441:    * to the curvature of the survival function. If, for the same date, we 
                   5442:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5443:    * to compare the new estimate of Life expectancy with the same linear 
                   5444:    * hypothesis. A more precise result, taking into account a more precise
                   5445:    * curvature will be obtained if estepm is as small as stepm. */
                   5446: 
                   5447:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5448:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5449:      nhstepm is the number of hstepm from age to agelim 
                   5450:      nstepm is the number of stepm from age to agelin. 
                   5451:      Look at hpijx to understand the reason of that which relies in memory size
                   5452:      and note for a fixed period like estepm months */
                   5453:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5454:      survival function given by stepm (the optimization length). Unfortunately it
                   5455:      means that if the survival funtion is printed only each two years of age and if
                   5456:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5457:      results. So we changed our mind and took the option of the best precision.
                   5458:   */
                   5459:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5460: 
                   5461:   /* If stepm=6 months */
                   5462:   /* nhstepm age range expressed in number of stepm */
                   5463:   agelim=AGESUP;
                   5464:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5465:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5466:   /* if (stepm >= YEARM) hstepm=1;*/
                   5467:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5468:   
                   5469:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5470:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5471:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5472:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5473:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5474:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5475: 
                   5476:   for (age=bage; age<=fage; age ++){ 
                   5477:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5478:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5479:     /* if (stepm >= YEARM) hstepm=1;*/
                   5480:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5481:                
1.126     brouard  5482:     /* If stepm=6 months */
                   5483:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5484:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5485:     
                   5486:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5487:                
1.126     brouard  5488:     /* Computing  Variances of health expectancies */
                   5489:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5490:        decrease memory allocation */
                   5491:     for(theta=1; theta <=npar; theta++){
                   5492:       for(i=1; i<=npar; i++){ 
1.222     brouard  5493:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5494:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5495:       }
1.235     brouard  5496:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5497:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5498:                        
1.126     brouard  5499:       for(j=1; j<= nlstate; j++){
1.222     brouard  5500:        for(i=1; i<=nlstate; i++){
                   5501:          for(h=0; h<=nhstepm-1; h++){
                   5502:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5503:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5504:          }
                   5505:        }
1.126     brouard  5506:       }
1.218     brouard  5507:                        
1.126     brouard  5508:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5509:        for(h=0; h<=nhstepm-1; h++){
                   5510:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5511:        }
1.126     brouard  5512:     }/* End theta */
                   5513:     
                   5514:     
                   5515:     for(h=0; h<=nhstepm-1; h++)
                   5516:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5517:        for(theta=1; theta <=npar; theta++)
                   5518:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5519:     
1.218     brouard  5520:                
1.222     brouard  5521:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5522:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5523:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5524:                
1.222     brouard  5525:     printf("%d|",(int)age);fflush(stdout);
                   5526:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5527:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5528:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5529:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5530:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5531:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5532:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5533:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5534:       }
                   5535:     }
1.218     brouard  5536:                
1.126     brouard  5537:     /* Computing expectancies */
1.235     brouard  5538:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5539:     for(i=1; i<=nlstate;i++)
                   5540:       for(j=1; j<=nlstate;j++)
1.222     brouard  5541:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5542:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5543:                                        
1.222     brouard  5544:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5545:                                        
1.222     brouard  5546:        }
1.218     brouard  5547:                
1.126     brouard  5548:     fprintf(ficresstdeij,"%3.0f",age );
                   5549:     for(i=1; i<=nlstate;i++){
                   5550:       eip=0.;
                   5551:       vip=0.;
                   5552:       for(j=1; j<=nlstate;j++){
1.222     brouard  5553:        eip += eij[i][j][(int)age];
                   5554:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5555:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5556:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5557:       }
                   5558:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5559:     }
                   5560:     fprintf(ficresstdeij,"\n");
1.218     brouard  5561:                
1.126     brouard  5562:     fprintf(ficrescveij,"%3.0f",age );
                   5563:     for(i=1; i<=nlstate;i++)
                   5564:       for(j=1; j<=nlstate;j++){
1.222     brouard  5565:        cptj= (j-1)*nlstate+i;
                   5566:        for(i2=1; i2<=nlstate;i2++)
                   5567:          for(j2=1; j2<=nlstate;j2++){
                   5568:            cptj2= (j2-1)*nlstate+i2;
                   5569:            if(cptj2 <= cptj)
                   5570:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5571:          }
1.126     brouard  5572:       }
                   5573:     fprintf(ficrescveij,"\n");
1.218     brouard  5574:                
1.126     brouard  5575:   }
                   5576:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5577:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5578:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5579:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5580:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5581:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5582:   printf("\n");
                   5583:   fprintf(ficlog,"\n");
1.218     brouard  5584:        
1.126     brouard  5585:   free_vector(xm,1,npar);
                   5586:   free_vector(xp,1,npar);
                   5587:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5588:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5589:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5590: }
1.218     brouard  5591:  
1.126     brouard  5592: /************ Variance ******************/
1.235     brouard  5593:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5594:  {
                   5595:    /* Variance of health expectancies */
                   5596:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5597:    /* double **newm;*/
                   5598:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5599:   
                   5600:    /* int movingaverage(); */
                   5601:    double **dnewm,**doldm;
                   5602:    double **dnewmp,**doldmp;
                   5603:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5604:    int k;
                   5605:    double *xp;
                   5606:    double **gp, **gm;  /* for var eij */
                   5607:    double ***gradg, ***trgradg; /*for var eij */
                   5608:    double **gradgp, **trgradgp; /* for var p point j */
                   5609:    double *gpp, *gmp; /* for var p point j */
                   5610:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5611:    double ***p3mat;
                   5612:    double age,agelim, hf;
                   5613:    /* double ***mobaverage; */
                   5614:    int theta;
                   5615:    char digit[4];
                   5616:    char digitp[25];
                   5617: 
                   5618:    char fileresprobmorprev[FILENAMELENGTH];
                   5619: 
                   5620:    if(popbased==1){
                   5621:      if(mobilav!=0)
                   5622:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5623:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5624:    }
                   5625:    else 
                   5626:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5627: 
1.218     brouard  5628:    /* if (mobilav!=0) { */
                   5629:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5630:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5631:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5632:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5633:    /*   } */
                   5634:    /* } */
                   5635: 
                   5636:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5637:    sprintf(digit,"%-d",ij);
                   5638:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5639:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5640:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5641:    strcat(fileresprobmorprev,fileresu);
                   5642:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5643:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5644:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5645:    }
                   5646:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5647:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5648:    pstamp(ficresprobmorprev);
                   5649:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5650:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5651:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5652:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5653:    }
                   5654:    for(j=1;j<=cptcoveff;j++) 
                   5655:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5656:    fprintf(ficresprobmorprev,"\n");
                   5657: 
1.218     brouard  5658:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5659:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5660:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5661:      for(i=1; i<=nlstate;i++)
                   5662:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5663:    }  
                   5664:    fprintf(ficresprobmorprev,"\n");
                   5665:   
                   5666:    fprintf(ficgp,"\n# Routine varevsij");
                   5667:    fprintf(ficgp,"\nunset title \n");
                   5668:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5669:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5670:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5671:    /*   } */
                   5672:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5673:    pstamp(ficresvij);
                   5674:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5675:    if(popbased==1)
                   5676:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5677:    else
                   5678:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5679:    fprintf(ficresvij,"# Age");
                   5680:    for(i=1; i<=nlstate;i++)
                   5681:      for(j=1; j<=nlstate;j++)
                   5682:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5683:    fprintf(ficresvij,"\n");
                   5684: 
                   5685:    xp=vector(1,npar);
                   5686:    dnewm=matrix(1,nlstate,1,npar);
                   5687:    doldm=matrix(1,nlstate,1,nlstate);
                   5688:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5689:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5690: 
                   5691:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5692:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5693:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5694:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5695:   
1.218     brouard  5696:    if(estepm < stepm){
                   5697:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5698:    }
                   5699:    else  hstepm=estepm;   
                   5700:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5701:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5702:       nhstepm is the number of hstepm from age to agelim 
                   5703:       nstepm is the number of stepm from age to agelim. 
                   5704:       Look at function hpijx to understand why because of memory size limitations, 
                   5705:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5706:       survival function given by stepm (the optimization length). Unfortunately it
                   5707:       means that if the survival funtion is printed every two years of age and if
                   5708:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5709:       results. So we changed our mind and took the option of the best precision.
                   5710:    */
                   5711:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5712:    agelim = AGESUP;
                   5713:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5714:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5715:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5716:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5717:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5718:      gp=matrix(0,nhstepm,1,nlstate);
                   5719:      gm=matrix(0,nhstepm,1,nlstate);
                   5720:                
                   5721:                
                   5722:      for(theta=1; theta <=npar; theta++){
                   5723:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5724:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5725:        }
                   5726:                        
1.242     brouard  5727:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5728:                        
                   5729:        if (popbased==1) {
                   5730:         if(mobilav ==0){
                   5731:           for(i=1; i<=nlstate;i++)
                   5732:             prlim[i][i]=probs[(int)age][i][ij];
                   5733:         }else{ /* mobilav */ 
                   5734:           for(i=1; i<=nlstate;i++)
                   5735:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5736:         }
                   5737:        }
                   5738:                        
1.235     brouard  5739:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5740:        for(j=1; j<= nlstate; j++){
                   5741:         for(h=0; h<=nhstepm; h++){
                   5742:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5743:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5744:         }
                   5745:        }
                   5746:        /* Next for computing probability of death (h=1 means
                   5747:          computed over hstepm matrices product = hstepm*stepm months) 
                   5748:          as a weighted average of prlim.
                   5749:        */
                   5750:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5751:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5752:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5753:        }    
                   5754:        /* end probability of death */
                   5755:                        
                   5756:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5757:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5758:                        
1.242     brouard  5759:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5760:                        
                   5761:        if (popbased==1) {
                   5762:         if(mobilav ==0){
                   5763:           for(i=1; i<=nlstate;i++)
                   5764:             prlim[i][i]=probs[(int)age][i][ij];
                   5765:         }else{ /* mobilav */ 
                   5766:           for(i=1; i<=nlstate;i++)
                   5767:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5768:         }
                   5769:        }
                   5770:                        
1.235     brouard  5771:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5772:                        
                   5773:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5774:         for(h=0; h<=nhstepm; h++){
                   5775:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5776:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5777:         }
                   5778:        }
                   5779:        /* This for computing probability of death (h=1 means
                   5780:          computed over hstepm matrices product = hstepm*stepm months) 
                   5781:          as a weighted average of prlim.
                   5782:        */
                   5783:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5784:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5785:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5786:        }    
                   5787:        /* end probability of death */
                   5788:                        
                   5789:        for(j=1; j<= nlstate; j++) /* vareij */
                   5790:         for(h=0; h<=nhstepm; h++){
                   5791:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5792:         }
                   5793:                        
                   5794:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5795:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5796:        }
                   5797:                        
                   5798:      } /* End theta */
                   5799:                
                   5800:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5801:                
                   5802:      for(h=0; h<=nhstepm; h++) /* veij */
                   5803:        for(j=1; j<=nlstate;j++)
                   5804:         for(theta=1; theta <=npar; theta++)
                   5805:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5806:                
                   5807:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5808:        for(theta=1; theta <=npar; theta++)
                   5809:         trgradgp[j][theta]=gradgp[theta][j];
                   5810:                
                   5811:                
                   5812:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5813:      for(i=1;i<=nlstate;i++)
                   5814:        for(j=1;j<=nlstate;j++)
                   5815:         vareij[i][j][(int)age] =0.;
                   5816:                
                   5817:      for(h=0;h<=nhstepm;h++){
                   5818:        for(k=0;k<=nhstepm;k++){
                   5819:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5820:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5821:         for(i=1;i<=nlstate;i++)
                   5822:           for(j=1;j<=nlstate;j++)
                   5823:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5824:        }
                   5825:      }
                   5826:                
                   5827:      /* pptj */
                   5828:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5829:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5830:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5831:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5832:         varppt[j][i]=doldmp[j][i];
                   5833:      /* end ppptj */
                   5834:      /*  x centered again */
                   5835:                
1.242     brouard  5836:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5837:                
                   5838:      if (popbased==1) {
                   5839:        if(mobilav ==0){
                   5840:         for(i=1; i<=nlstate;i++)
                   5841:           prlim[i][i]=probs[(int)age][i][ij];
                   5842:        }else{ /* mobilav */ 
                   5843:         for(i=1; i<=nlstate;i++)
                   5844:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5845:        }
                   5846:      }
                   5847:                
                   5848:      /* This for computing probability of death (h=1 means
                   5849:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5850:        as a weighted average of prlim.
                   5851:      */
1.235     brouard  5852:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5853:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5854:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5855:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5856:      }    
                   5857:      /* end probability of death */
                   5858:                
                   5859:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5860:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5861:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5862:        for(i=1; i<=nlstate;i++){
                   5863:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5864:        }
                   5865:      } 
                   5866:      fprintf(ficresprobmorprev,"\n");
                   5867:                
                   5868:      fprintf(ficresvij,"%.0f ",age );
                   5869:      for(i=1; i<=nlstate;i++)
                   5870:        for(j=1; j<=nlstate;j++){
                   5871:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5872:        }
                   5873:      fprintf(ficresvij,"\n");
                   5874:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5875:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5876:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5877:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5878:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5879:    } /* End age */
                   5880:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5881:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5882:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5883:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5884:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5885:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5886:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5887:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5888:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5889:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5890:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5891:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5892:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5893:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5894:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5895:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5896:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5897:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5898:     */
1.218     brouard  5899:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5900:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5901: 
1.218     brouard  5902:    free_vector(xp,1,npar);
                   5903:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5904:    free_matrix(dnewm,1,nlstate,1,npar);
                   5905:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5906:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5907:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5908:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5909:    fclose(ficresprobmorprev);
                   5910:    fflush(ficgp);
                   5911:    fflush(fichtm); 
                   5912:  }  /* end varevsij */
1.126     brouard  5913: 
                   5914: /************ Variance of prevlim ******************/
1.235     brouard  5915:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5916: {
1.205     brouard  5917:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5918:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5919: 
1.126     brouard  5920:   double **dnewm,**doldm;
                   5921:   int i, j, nhstepm, hstepm;
                   5922:   double *xp;
                   5923:   double *gp, *gm;
                   5924:   double **gradg, **trgradg;
1.208     brouard  5925:   double **mgm, **mgp;
1.126     brouard  5926:   double age,agelim;
                   5927:   int theta;
                   5928:   
                   5929:   pstamp(ficresvpl);
                   5930:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5931:   fprintf(ficresvpl,"# Age ");
                   5932:   if(nresult >=1)
                   5933:     fprintf(ficresvpl," Result# ");
1.126     brouard  5934:   for(i=1; i<=nlstate;i++)
                   5935:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5936:   fprintf(ficresvpl,"\n");
                   5937: 
                   5938:   xp=vector(1,npar);
                   5939:   dnewm=matrix(1,nlstate,1,npar);
                   5940:   doldm=matrix(1,nlstate,1,nlstate);
                   5941:   
                   5942:   hstepm=1*YEARM; /* Every year of age */
                   5943:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5944:   agelim = AGESUP;
                   5945:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5946:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5947:     if (stepm >= YEARM) hstepm=1;
                   5948:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5949:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5950:     mgp=matrix(1,npar,1,nlstate);
                   5951:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5952:     gp=vector(1,nlstate);
                   5953:     gm=vector(1,nlstate);
                   5954: 
                   5955:     for(theta=1; theta <=npar; theta++){
                   5956:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5957:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5958:       }
1.209     brouard  5959:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5960:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5961:       else
1.235     brouard  5962:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5963:       for(i=1;i<=nlstate;i++){
1.126     brouard  5964:        gp[i] = prlim[i][i];
1.208     brouard  5965:        mgp[theta][i] = prlim[i][i];
                   5966:       }
1.126     brouard  5967:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5968:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5969:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5970:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5971:       else
1.235     brouard  5972:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5973:       for(i=1;i<=nlstate;i++){
1.126     brouard  5974:        gm[i] = prlim[i][i];
1.208     brouard  5975:        mgm[theta][i] = prlim[i][i];
                   5976:       }
1.126     brouard  5977:       for(i=1;i<=nlstate;i++)
                   5978:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5979:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5980:     } /* End theta */
                   5981: 
                   5982:     trgradg =matrix(1,nlstate,1,npar);
                   5983: 
                   5984:     for(j=1; j<=nlstate;j++)
                   5985:       for(theta=1; theta <=npar; theta++)
                   5986:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5987:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5988:     /*   printf("\nmgm mgp %d ",(int)age); */
                   5989:     /*   for(j=1; j<=nlstate;j++){ */
                   5990:     /*         printf(" %d ",j); */
                   5991:     /*         for(theta=1; theta <=npar; theta++) */
                   5992:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   5993:     /*         printf("\n "); */
                   5994:     /*   } */
                   5995:     /* } */
                   5996:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   5997:     /*   printf("\n gradg %d ",(int)age); */
                   5998:     /*   for(j=1; j<=nlstate;j++){ */
                   5999:     /*         printf("%d ",j); */
                   6000:     /*         for(theta=1; theta <=npar; theta++) */
                   6001:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6002:     /*         printf("\n "); */
                   6003:     /*   } */
                   6004:     /* } */
1.126     brouard  6005: 
                   6006:     for(i=1;i<=nlstate;i++)
                   6007:       varpl[i][(int)age] =0.;
1.209     brouard  6008:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  6009:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6010:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   6011:     }else{
1.126     brouard  6012:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6013:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6014:     }
1.126     brouard  6015:     for(i=1;i<=nlstate;i++)
                   6016:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6017: 
                   6018:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6019:     if(nresult >=1)
                   6020:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6021:     for(i=1; i<=nlstate;i++)
                   6022:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6023:     fprintf(ficresvpl,"\n");
                   6024:     free_vector(gp,1,nlstate);
                   6025:     free_vector(gm,1,nlstate);
1.208     brouard  6026:     free_matrix(mgm,1,npar,1,nlstate);
                   6027:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6028:     free_matrix(gradg,1,npar,1,nlstate);
                   6029:     free_matrix(trgradg,1,nlstate,1,npar);
                   6030:   } /* End age */
                   6031: 
                   6032:   free_vector(xp,1,npar);
                   6033:   free_matrix(doldm,1,nlstate,1,npar);
                   6034:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6035: 
                   6036: }
                   6037: 
                   6038: /************ Variance of one-step probabilities  ******************/
                   6039: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6040:  {
                   6041:    int i, j=0,  k1, l1, tj;
                   6042:    int k2, l2, j1,  z1;
                   6043:    int k=0, l;
                   6044:    int first=1, first1, first2;
                   6045:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6046:    double **dnewm,**doldm;
                   6047:    double *xp;
                   6048:    double *gp, *gm;
                   6049:    double **gradg, **trgradg;
                   6050:    double **mu;
                   6051:    double age, cov[NCOVMAX+1];
                   6052:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6053:    int theta;
                   6054:    char fileresprob[FILENAMELENGTH];
                   6055:    char fileresprobcov[FILENAMELENGTH];
                   6056:    char fileresprobcor[FILENAMELENGTH];
                   6057:    double ***varpij;
                   6058: 
                   6059:    strcpy(fileresprob,"PROB_"); 
                   6060:    strcat(fileresprob,fileres);
                   6061:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6062:      printf("Problem with resultfile: %s\n", fileresprob);
                   6063:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6064:    }
                   6065:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6066:    strcat(fileresprobcov,fileresu);
                   6067:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6068:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6069:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6070:    }
                   6071:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6072:    strcat(fileresprobcor,fileresu);
                   6073:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6074:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6075:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6076:    }
                   6077:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6078:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6079:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6080:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6081:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6082:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6083:    pstamp(ficresprob);
                   6084:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6085:    fprintf(ficresprob,"# Age");
                   6086:    pstamp(ficresprobcov);
                   6087:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6088:    fprintf(ficresprobcov,"# Age");
                   6089:    pstamp(ficresprobcor);
                   6090:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6091:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6092: 
                   6093: 
1.222     brouard  6094:    for(i=1; i<=nlstate;i++)
                   6095:      for(j=1; j<=(nlstate+ndeath);j++){
                   6096:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6097:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6098:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6099:      }  
                   6100:    /* fprintf(ficresprob,"\n");
                   6101:       fprintf(ficresprobcov,"\n");
                   6102:       fprintf(ficresprobcor,"\n");
                   6103:    */
                   6104:    xp=vector(1,npar);
                   6105:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6106:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6107:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6108:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6109:    first=1;
                   6110:    fprintf(ficgp,"\n# Routine varprob");
                   6111:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6112:    fprintf(fichtm,"\n");
                   6113: 
                   6114:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6115:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6116:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6117: and drawn. It helps understanding how is the covariance between two incidences.\
                   6118:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6119:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6120: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6121: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6122: standard deviations wide on each axis. <br>\
                   6123:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6124:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6125: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6126: 
1.222     brouard  6127:    cov[1]=1;
                   6128:    /* tj=cptcoveff; */
1.225     brouard  6129:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6130:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6131:    j1=0;
1.224     brouard  6132:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6133:      if  (cptcovn>0) {
                   6134:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6135:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6136:        fprintf(ficresprob, "**********\n#\n");
                   6137:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6138:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6139:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6140:                        
1.222     brouard  6141:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6142:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6143:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6144:                        
                   6145:                        
1.222     brouard  6146:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6147:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6148:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6149:                        
1.222     brouard  6150:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6151:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6152:        fprintf(ficresprobcor, "**********\n#");    
                   6153:        if(invalidvarcomb[j1]){
                   6154:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6155:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6156:         continue;
                   6157:        }
                   6158:      }
                   6159:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6160:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6161:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6162:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6163:      for (age=bage; age<=fage; age ++){ 
                   6164:        cov[2]=age;
                   6165:        if(nagesqr==1)
                   6166:         cov[3]= age*age;
                   6167:        for (k=1; k<=cptcovn;k++) {
                   6168:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6169:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6170:                                                                    * 1  1 1 1 1
                   6171:                                                                    * 2  2 1 1 1
                   6172:                                                                    * 3  1 2 1 1
                   6173:                                                                    */
                   6174:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6175:        }
                   6176:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6177:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6178:        for (k=1; k<=cptcovprod;k++)
                   6179:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6180:                        
                   6181:                        
1.222     brouard  6182:        for(theta=1; theta <=npar; theta++){
                   6183:         for(i=1; i<=npar; i++)
                   6184:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6185:                                
1.222     brouard  6186:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6187:                                
1.222     brouard  6188:         k=0;
                   6189:         for(i=1; i<= (nlstate); i++){
                   6190:           for(j=1; j<=(nlstate+ndeath);j++){
                   6191:             k=k+1;
                   6192:             gp[k]=pmmij[i][j];
                   6193:           }
                   6194:         }
1.220     brouard  6195:                                
1.222     brouard  6196:         for(i=1; i<=npar; i++)
                   6197:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6198:                                
1.222     brouard  6199:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6200:         k=0;
                   6201:         for(i=1; i<=(nlstate); i++){
                   6202:           for(j=1; j<=(nlstate+ndeath);j++){
                   6203:             k=k+1;
                   6204:             gm[k]=pmmij[i][j];
                   6205:           }
                   6206:         }
1.220     brouard  6207:                                
1.222     brouard  6208:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6209:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6210:        }
1.126     brouard  6211: 
1.222     brouard  6212:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6213:         for(theta=1; theta <=npar; theta++)
                   6214:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6215:                        
1.222     brouard  6216:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6217:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6218:                        
1.222     brouard  6219:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6220:                        
1.222     brouard  6221:        k=0;
                   6222:        for(i=1; i<=(nlstate); i++){
                   6223:         for(j=1; j<=(nlstate+ndeath);j++){
                   6224:           k=k+1;
                   6225:           mu[k][(int) age]=pmmij[i][j];
                   6226:         }
                   6227:        }
                   6228:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6229:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6230:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6231:                        
1.222     brouard  6232:        /*printf("\n%d ",(int)age);
                   6233:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6234:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6235:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6236:         }*/
1.220     brouard  6237:                        
1.222     brouard  6238:        fprintf(ficresprob,"\n%d ",(int)age);
                   6239:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6240:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6241:                        
1.222     brouard  6242:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6243:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6244:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6245:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6246:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6247:        }
                   6248:        i=0;
                   6249:        for (k=1; k<=(nlstate);k++){
                   6250:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6251:           i++;
                   6252:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6253:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6254:           for (j=1; j<=i;j++){
                   6255:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6256:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6257:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6258:           }
                   6259:         }
                   6260:        }/* end of loop for state */
                   6261:      } /* end of loop for age */
                   6262:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6263:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6264:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6265:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6266:     
                   6267:      /* Confidence intervalle of pij  */
                   6268:      /*
                   6269:        fprintf(ficgp,"\nunset parametric;unset label");
                   6270:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6271:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6272:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6273:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6274:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6275:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6276:      */
                   6277:                
                   6278:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6279:      first1=1;first2=2;
                   6280:      for (k2=1; k2<=(nlstate);k2++){
                   6281:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6282:         if(l2==k2) continue;
                   6283:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6284:         for (k1=1; k1<=(nlstate);k1++){
                   6285:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6286:             if(l1==k1) continue;
                   6287:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6288:             if(i<=j) continue;
                   6289:             for (age=bage; age<=fage; age ++){ 
                   6290:               if ((int)age %5==0){
                   6291:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6292:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6293:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6294:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6295:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6296:                 c12=cv12/sqrt(v1*v2);
                   6297:                 /* Computing eigen value of matrix of covariance */
                   6298:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6299:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6300:                 if ((lc2 <0) || (lc1 <0) ){
                   6301:                   if(first2==1){
                   6302:                     first1=0;
                   6303:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6304:                   }
                   6305:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6306:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6307:                   /* lc2=fabs(lc2); */
                   6308:                 }
1.220     brouard  6309:                                                                
1.222     brouard  6310:                 /* Eigen vectors */
                   6311:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6312:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6313:                 v21=(lc1-v1)/cv12*v11;
                   6314:                 v12=-v21;
                   6315:                 v22=v11;
                   6316:                 tnalp=v21/v11;
                   6317:                 if(first1==1){
                   6318:                   first1=0;
                   6319:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6320:                 }
                   6321:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6322:                 /*printf(fignu*/
                   6323:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6324:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6325:                 if(first==1){
                   6326:                   first=0;
                   6327:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6328:                   fprintf(ficgp,"\nset parametric;unset label");
                   6329:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6330:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6331:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6332:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6333: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6334:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6335:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6336:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6337:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6338:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6339:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6340:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6341:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6342:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6343:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6344:                 }else{
                   6345:                   first=0;
                   6346:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6347:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6348:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6349:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6350:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6351:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6352:                 }/* if first */
                   6353:               } /* age mod 5 */
                   6354:             } /* end loop age */
                   6355:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6356:             first=1;
                   6357:           } /*l12 */
                   6358:         } /* k12 */
                   6359:        } /*l1 */
                   6360:      }/* k1 */
                   6361:    }  /* loop on combination of covariates j1 */
                   6362:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6363:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6364:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6365:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6366:    free_vector(xp,1,npar);
                   6367:    fclose(ficresprob);
                   6368:    fclose(ficresprobcov);
                   6369:    fclose(ficresprobcor);
                   6370:    fflush(ficgp);
                   6371:    fflush(fichtmcov);
                   6372:  }
1.126     brouard  6373: 
                   6374: 
                   6375: /******************* Printing html file ***********/
1.201     brouard  6376: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6377:                  int lastpass, int stepm, int weightopt, char model[],\
                   6378:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258   ! brouard  6379:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6380:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6381:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6382:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6383: 
                   6384:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6385:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6386: </ul>");
1.237     brouard  6387:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6388: </ul>", model);
1.214     brouard  6389:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6390:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6391:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6392:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6393:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6394:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6395:    fprintf(fichtm,"\
                   6396:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6397:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6398:    fprintf(fichtm,"\
1.217     brouard  6399:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6400:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6401:    fprintf(fichtm,"\
1.126     brouard  6402:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6403:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6404:    fprintf(fichtm,"\
1.217     brouard  6405:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6406:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6407:    fprintf(fichtm,"\
1.211     brouard  6408:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6409:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6410:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6411:    if(prevfcast==1){
                   6412:      fprintf(fichtm,"\
                   6413:  - Prevalence projections by age and states:                           \
1.201     brouard  6414:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6415:    }
1.126     brouard  6416: 
1.222     brouard  6417:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6418: 
1.225     brouard  6419:    m=pow(2,cptcoveff);
1.222     brouard  6420:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6421: 
1.222     brouard  6422:    jj1=0;
1.237     brouard  6423: 
                   6424:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6425:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6426:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6427:        continue;
1.220     brouard  6428: 
1.222     brouard  6429:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6430:      jj1++;
                   6431:      if (cptcovn > 0) {
                   6432:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6433:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6434:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6435:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6436:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6437:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6438:        }
1.237     brouard  6439:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6440:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6441:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6442:       }
                   6443:        
1.230     brouard  6444:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6445:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6446:        if(invalidvarcomb[k1]){
                   6447:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6448:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6449:         continue;
                   6450:        }
                   6451:      }
                   6452:      /* aij, bij */
1.241     brouard  6453:      fprintf(fichtm,"<br>- Logit model (yours is: 1+age+%s), for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
                   6454: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6455:      /* Pij */
1.241     brouard  6456:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6457: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6458:      /* Quasi-incidences */
                   6459:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6460:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6461:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6462: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6463: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6464:      /* Survival functions (period) in state j */
                   6465:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6466:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6467: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6468:      }
                   6469:      /* State specific survival functions (period) */
                   6470:      for(cpt=1; cpt<=nlstate;cpt++){
                   6471:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6472:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6473:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6474:      }
                   6475:      /* Period (stable) prevalence in each health state */
                   6476:      for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6477:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d some years earlier, knowing that we will be in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6478: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6479:      }
                   6480:      if(backcast==1){
                   6481:        /* Period (stable) back prevalence in each health state */
                   6482:        for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6483:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability to be in state %d at a younger age, knowing that we will be in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6484: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6485:        }
1.217     brouard  6486:      }
1.222     brouard  6487:      if(prevfcast==1){
                   6488:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6489:        for(cpt=1; cpt<=nlstate;cpt++){
1.258   ! brouard  6490:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
        !          6491: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6492:        }
                   6493:      }
1.220     brouard  6494:         
1.222     brouard  6495:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6496:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6497: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6498:      }
                   6499:      /* } /\* end i1 *\/ */
                   6500:    }/* End k1 */
                   6501:    fprintf(fichtm,"</ul>");
1.126     brouard  6502: 
1.222     brouard  6503:    fprintf(fichtm,"\
1.126     brouard  6504: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6505:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6506:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6507: But because parameters are usually highly correlated (a higher incidence of disability \
                   6508: and a higher incidence of recovery can give very close observed transition) it might \
                   6509: be very useful to look not only at linear confidence intervals estimated from the \
                   6510: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6511: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6512: covariance matrix of the one-step probabilities. \
                   6513: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6514: 
1.222     brouard  6515:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6516:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6517:    fprintf(fichtm,"\
1.126     brouard  6518:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6519:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6520: 
1.222     brouard  6521:    fprintf(fichtm,"\
1.126     brouard  6522:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6523:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6524:    fprintf(fichtm,"\
1.126     brouard  6525:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6526:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6527:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6528:    fprintf(fichtm,"\
1.126     brouard  6529:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6530:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6531:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6532:    fprintf(fichtm,"\
1.128     brouard  6533:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6534:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6535:    fprintf(fichtm,"\
1.128     brouard  6536:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6537:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6538:    fprintf(fichtm,"\
1.126     brouard  6539:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6540:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6541: 
                   6542: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6543: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6544: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6545: /*     <br>",fileres,fileres,fileres,fileres); */
                   6546: /*  else  */
                   6547: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6548:    fflush(fichtm);
                   6549:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6550: 
1.225     brouard  6551:    m=pow(2,cptcoveff);
1.222     brouard  6552:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6553: 
1.222     brouard  6554:    jj1=0;
1.237     brouard  6555: 
1.241     brouard  6556:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6557:    for(k1=1; k1<=m;k1++){
1.253     brouard  6558:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6559:        continue;
1.222     brouard  6560:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6561:      jj1++;
1.126     brouard  6562:      if (cptcovn > 0) {
                   6563:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6564:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6565:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6566:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6567:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6568:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6569:       }
                   6570: 
1.126     brouard  6571:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6572: 
1.222     brouard  6573:        if(invalidvarcomb[k1]){
                   6574:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6575:         continue;
                   6576:        }
1.126     brouard  6577:      }
                   6578:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258   ! brouard  6579:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6580: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258   ! brouard  6581: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6582:      }
                   6583:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6584: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6585: true period expectancies (those weighted with period prevalences are also\
                   6586:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6587:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6588: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6589:      /* } /\* end i1 *\/ */
                   6590:    }/* End k1 */
1.241     brouard  6591:   }/* End nres */
1.222     brouard  6592:    fprintf(fichtm,"</ul>");
                   6593:    fflush(fichtm);
1.126     brouard  6594: }
                   6595: 
                   6596: /******************* Gnuplot file **************/
1.223     brouard  6597: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6598: 
                   6599:   char dirfileres[132],optfileres[132];
1.223     brouard  6600:   char gplotcondition[132];
1.237     brouard  6601:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6602:   int lv=0, vlv=0, kl=0;
1.130     brouard  6603:   int ng=0;
1.201     brouard  6604:   int vpopbased;
1.223     brouard  6605:   int ioffset; /* variable offset for columns */
1.235     brouard  6606:   int nres=0; /* Index of resultline */
1.219     brouard  6607: 
1.126     brouard  6608: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6609: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6610: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6611: /*   } */
                   6612: 
                   6613:   /*#ifdef windows */
                   6614:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6615:   /*#endif */
1.225     brouard  6616:   m=pow(2,cptcoveff);
1.126     brouard  6617: 
1.202     brouard  6618:   /* Contribution to likelihood */
                   6619:   /* Plot the probability implied in the likelihood */
1.223     brouard  6620:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6621:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6622:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6623:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6624: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6625:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6626: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6627:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6628:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6629:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6630:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6631:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6632:   for (i=1; i<= nlstate ; i ++) {
                   6633:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6634:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6635:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6636:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6637:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6638:     }
                   6639:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6640:   }
                   6641:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6642:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6643:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6644:   fprintf(ficgp,"\nset out;unset log\n");
                   6645:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6646: 
1.126     brouard  6647:   strcpy(dirfileres,optionfilefiname);
                   6648:   strcpy(optfileres,"vpl");
1.223     brouard  6649:   /* 1eme*/
1.238     brouard  6650:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6651:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6652:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6653:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6654:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6655:          continue;
                   6656:        /* We are interested in selected combination by the resultline */
1.246     brouard  6657:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6658:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6659:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6660:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6661:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6662:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6663:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6664:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6665:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6666:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6667:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6668:        }
                   6669:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6670:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6671:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6672:        }       
1.246     brouard  6673:        /* printf("\n#\n"); */
1.238     brouard  6674:        fprintf(ficgp,"\n#\n");
                   6675:        if(invalidvarcomb[k1]){
                   6676:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6677:          continue;
                   6678:        }
1.235     brouard  6679:       
1.241     brouard  6680:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6681:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
                   6682:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.235     brouard  6683:       
1.238     brouard  6684:        for (i=1; i<= nlstate ; i ++) {
                   6685:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6686:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6687:        }
1.242     brouard  6688:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres);
1.238     brouard  6689:        for (i=1; i<= nlstate ; i ++) {
                   6690:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6691:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6692:        } 
1.242     brouard  6693:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); 
1.238     brouard  6694:        for (i=1; i<= nlstate ; i ++) {
                   6695:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6696:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6697:        }  
                   6698:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6699:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6700:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6701:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6702:          if(cptcoveff ==0){
1.245     brouard  6703:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6704:          }else{
                   6705:            kl=0;
                   6706:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6707:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6708:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6709:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6710:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6711:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6712:              kl++;
1.238     brouard  6713:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6714:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6715:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6716:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6717:              if(k==cptcoveff){
1.245     brouard  6718:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6719:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6720:              }else{
                   6721:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6722:                kl++;
                   6723:              }
                   6724:            } /* end covariate */
                   6725:          } /* end if no covariate */
                   6726:        } /* end if backcast */
                   6727:        fprintf(ficgp,"\nset out \n");
                   6728:       } /* nres */
1.201     brouard  6729:     } /* k1 */
                   6730:   } /* cpt */
1.235     brouard  6731: 
                   6732:   
1.126     brouard  6733:   /*2 eme*/
1.238     brouard  6734:   for (k1=1; k1<= m ; k1 ++){  
                   6735:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6736:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6737:        continue;
                   6738:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6739:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6740:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6741:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6742:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6743:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6744:        vlv= nbcode[Tvaraff[k]][lv];
                   6745:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6746:       }
1.237     brouard  6747:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6748:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6749:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6750:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6751:       }
1.211     brouard  6752:       fprintf(ficgp,"\n#\n");
1.223     brouard  6753:       if(invalidvarcomb[k1]){
                   6754:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6755:        continue;
                   6756:       }
1.219     brouard  6757:                        
1.241     brouard  6758:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6759:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6760:        if(vpopbased==0)
                   6761:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6762:        else
                   6763:          fprintf(ficgp,"\nreplot ");
                   6764:        for (i=1; i<= nlstate+1 ; i ++) {
                   6765:          k=2*i;
                   6766:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
                   6767:          for (j=1; j<= nlstate+1 ; j ++) {
                   6768:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6769:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6770:          }   
                   6771:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6772:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
                   6773:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6774:          for (j=1; j<= nlstate+1 ; j ++) {
                   6775:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6776:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6777:          }   
                   6778:          fprintf(ficgp,"\" t\"\" w l lt 0,");
                   6779:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
                   6780:          for (j=1; j<= nlstate+1 ; j ++) {
                   6781:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6782:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6783:          }   
                   6784:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6785:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6786:        } /* state */
                   6787:       } /* vpopbased */
1.244     brouard  6788:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6789:     } /* end nres */
                   6790:   } /* k1 end 2 eme*/
                   6791:        
                   6792:        
                   6793:   /*3eme*/
                   6794:   for (k1=1; k1<= m ; k1 ++){
                   6795:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6796:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6797:        continue;
                   6798: 
                   6799:       for (cpt=1; cpt<= nlstate ; cpt ++) {
                   6800:        fprintf(ficgp,"\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
                   6801:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6802:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6803:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6804:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6805:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6806:          vlv= nbcode[Tvaraff[k]][lv];
                   6807:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6808:        }
                   6809:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6810:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6811:        }       
                   6812:        fprintf(ficgp,"\n#\n");
                   6813:        if(invalidvarcomb[k1]){
                   6814:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6815:          continue;
                   6816:        }
                   6817:                        
                   6818:        /*       k=2+nlstate*(2*cpt-2); */
                   6819:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6820:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6821:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.201     brouard  6822: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
1.238     brouard  6823:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6824:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6825:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6826:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6827:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6828:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6829:                                
1.238     brouard  6830:        */
                   6831:        for (i=1; i< nlstate ; i ++) {
                   6832:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
                   6833:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6834:                                
1.238     brouard  6835:        } 
                   6836:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
                   6837:       }
                   6838:     } /* end nres */
                   6839:   } /* end kl 3eme */
1.126     brouard  6840:   
1.223     brouard  6841:   /* 4eme */
1.201     brouard  6842:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6843:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6844:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6845:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6846:        continue;
1.238     brouard  6847:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6848:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6849:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6850:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6851:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6852:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6853:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6854:          vlv= nbcode[Tvaraff[k]][lv];
                   6855:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6856:        }
                   6857:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6858:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6859:        }       
                   6860:        fprintf(ficgp,"\n#\n");
                   6861:        if(invalidvarcomb[k1]){
                   6862:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6863:          continue;
1.223     brouard  6864:        }
1.238     brouard  6865:       
1.241     brouard  6866:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6867:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6868: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6869:        k=3;
                   6870:        for (i=1; i<= nlstate ; i ++){
                   6871:          if(i==1){
                   6872:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6873:          }else{
                   6874:            fprintf(ficgp,", '' ");
                   6875:          }
                   6876:          l=(nlstate+ndeath)*(i-1)+1;
                   6877:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6878:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6879:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6880:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6881:        } /* nlstate */
                   6882:        fprintf(ficgp,"\nset out\n");
                   6883:       } /* end cpt state*/ 
                   6884:     } /* end nres */
                   6885:   } /* end covariate k1 */  
                   6886: 
1.220     brouard  6887: /* 5eme */
1.201     brouard  6888:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6889:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6890:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6891:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6892:        continue;
1.238     brouard  6893:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6894:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6895:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6896:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6897:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6898:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6899:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6900:          vlv= nbcode[Tvaraff[k]][lv];
                   6901:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6902:        }
                   6903:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6904:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6905:        }       
                   6906:        fprintf(ficgp,"\n#\n");
                   6907:        if(invalidvarcomb[k1]){
                   6908:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6909:          continue;
                   6910:        }
1.227     brouard  6911:       
1.241     brouard  6912:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6913:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6914: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6915:        k=3;
                   6916:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6917:          if(j==1)
                   6918:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6919:          else
                   6920:            fprintf(ficgp,", '' ");
                   6921:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6922:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6923:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6924:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6925:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6926:        } /* nlstate */
                   6927:        fprintf(ficgp,", '' ");
                   6928:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6929:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6930:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6931:          if(j < nlstate)
                   6932:            fprintf(ficgp,"$%d +",k+l);
                   6933:          else
                   6934:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6935:        }
                   6936:        fprintf(ficgp,"\nset out\n");
                   6937:       } /* end cpt state*/ 
                   6938:     } /* end covariate */  
                   6939:   } /* end nres */
1.227     brouard  6940:   
1.220     brouard  6941: /* 6eme */
1.202     brouard  6942:   /* CV preval stable (period) for each covariate */
1.237     brouard  6943:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6944:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6945:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6946:       continue;
1.255     brouard  6947:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.227     brouard  6948:       
1.211     brouard  6949:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6950:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6951:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6952:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6953:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6954:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6955:        vlv= nbcode[Tvaraff[k]][lv];
                   6956:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6957:       }
1.237     brouard  6958:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6959:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6960:       }        
1.211     brouard  6961:       fprintf(ficgp,"\n#\n");
1.223     brouard  6962:       if(invalidvarcomb[k1]){
1.227     brouard  6963:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6964:        continue;
1.223     brouard  6965:       }
1.227     brouard  6966:       
1.241     brouard  6967:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6968:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6969: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6970:       k=3; /* Offset */
1.255     brouard  6971:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  6972:        if(i==1)
                   6973:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6974:        else
                   6975:          fprintf(ficgp,", '' ");
1.255     brouard  6976:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  6977:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6978:        for (j=2; j<= nlstate ; j ++)
                   6979:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6980:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6981:       } /* nlstate */
1.201     brouard  6982:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6983:     } /* end cpt state*/ 
                   6984:   } /* end covariate */  
1.227     brouard  6985:   
                   6986:   
1.220     brouard  6987: /* 7eme */
1.218     brouard  6988:   if(backcast == 1){
1.217     brouard  6989:     /* CV back preval stable (period) for each covariate */
1.237     brouard  6990:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6991:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6992:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6993:        continue;
1.255     brouard  6994:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
                   6995:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  6996:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6997:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6998:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6999:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7000:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7001:          vlv= nbcode[Tvaraff[k]][lv];
                   7002:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7003:        }
1.237     brouard  7004:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7005:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7006:        }       
1.227     brouard  7007:        fprintf(ficgp,"\n#\n");
                   7008:        if(invalidvarcomb[k1]){
                   7009:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7010:          continue;
                   7011:        }
                   7012:        
1.241     brouard  7013:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  7014:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7015: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7016:        k=3; /* Offset */
1.255     brouard  7017:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7018:          if(i==1)
                   7019:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7020:          else
                   7021:            fprintf(ficgp,", '' ");
                   7022:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7023:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7024:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7025:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7026:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7027:          /* for (j=2; j<= nlstate ; j ++) */
                   7028:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7029:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7030:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7031:        } /* nlstate */
                   7032:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7033:       } /* end cpt state*/ 
                   7034:     } /* end covariate */  
                   7035:   } /* End if backcast */
                   7036:   
1.223     brouard  7037:   /* 8eme */
1.218     brouard  7038:   if(prevfcast==1){
                   7039:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7040:     
1.237     brouard  7041:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7042:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7043:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7044:        continue;
1.211     brouard  7045:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7046:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7047:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7048:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7049:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7050:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7051:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7052:          vlv= nbcode[Tvaraff[k]][lv];
                   7053:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7054:        }
1.237     brouard  7055:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7056:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7057:        }       
1.227     brouard  7058:        fprintf(ficgp,"\n#\n");
                   7059:        if(invalidvarcomb[k1]){
                   7060:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7061:          continue;
                   7062:        }
                   7063:        
                   7064:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7065:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7066:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7067: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7068:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7069:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7070:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7071:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7072:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7073:          if(i==1){
                   7074:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7075:          }else{
                   7076:            fprintf(ficgp,",\\\n '' ");
                   7077:          }
                   7078:          if(cptcoveff ==0){ /* No covariate */
                   7079:            ioffset=2; /* Age is in 2 */
                   7080:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7081:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7082:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7083:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7084:            fprintf(ficgp," u %d:(", ioffset); 
                   7085:            if(i==nlstate+1)
                   7086:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7087:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7088:            else
                   7089:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7090:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7091:          }else{ /* more than 2 covariates */
                   7092:            if(cptcoveff ==1){
                   7093:              ioffset=4; /* Age is in 4 */
                   7094:            }else{
                   7095:              ioffset=6; /* Age is in 6 */
                   7096:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7097:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7098:            }   
                   7099:            fprintf(ficgp," u %d:(",ioffset); 
                   7100:            kl=0;
                   7101:            strcpy(gplotcondition,"(");
                   7102:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7103:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7104:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7105:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7106:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7107:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7108:              kl++;
                   7109:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7110:              kl++;
                   7111:              if(k <cptcoveff && cptcoveff>1)
                   7112:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7113:            }
                   7114:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7115:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7116:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7117:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7118:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7119:            if(i==nlstate+1){
                   7120:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7121:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7122:            }else{
                   7123:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7124:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7125:            }
                   7126:          } /* end if covariate */
                   7127:        } /* nlstate */
                   7128:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7129:       } /* end cpt state*/
                   7130:     } /* end covariate */
                   7131:   } /* End if prevfcast */
1.227     brouard  7132:   
                   7133:   
1.238     brouard  7134:   /* 9eme writing MLE parameters */
                   7135:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7136:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7137:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7138:     for(k=1; k <=(nlstate+ndeath); k++){
                   7139:       if (k != i) {
1.227     brouard  7140:        fprintf(ficgp,"#   current state %d\n",k);
                   7141:        for(j=1; j <=ncovmodel; j++){
                   7142:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7143:          jk++; 
                   7144:        }
                   7145:        fprintf(ficgp,"\n");
1.126     brouard  7146:       }
                   7147:     }
1.223     brouard  7148:   }
1.187     brouard  7149:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7150:   
1.145     brouard  7151:   /*goto avoid;*/
1.238     brouard  7152:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7153:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7154:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7155:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7156:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7157:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7158:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7159:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7160:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7161:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7162:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7163:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7164:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7165:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7166:   fprintf(ficgp,"#\n");
1.223     brouard  7167:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7168:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7169:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7170:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7171:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7172:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7173:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7174:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7175:        continue;
                   7176:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7177:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7178:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7179:       }        
                   7180:       fprintf(ficgp,"\n#\n");
1.241     brouard  7181:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7182:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7183:       if (ng==1){
                   7184:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7185:        fprintf(ficgp,"\nunset log y");
                   7186:       }else if (ng==2){
                   7187:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7188:        fprintf(ficgp,"\nset log y");
                   7189:       }else if (ng==3){
                   7190:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7191:        fprintf(ficgp,"\nset log y");
                   7192:       }else
                   7193:        fprintf(ficgp,"\nunset title ");
                   7194:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7195:       i=1;
                   7196:       for(k2=1; k2<=nlstate; k2++) {
                   7197:        k3=i;
                   7198:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7199:          if (k != k2){
                   7200:            switch( ng) {
                   7201:            case 1:
                   7202:              if(nagesqr==0)
                   7203:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7204:              else /* nagesqr =1 */
                   7205:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7206:              break;
                   7207:            case 2: /* ng=2 */
                   7208:              if(nagesqr==0)
                   7209:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7210:              else /* nagesqr =1 */
                   7211:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7212:              break;
                   7213:            case 3:
                   7214:              if(nagesqr==0)
                   7215:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7216:              else /* nagesqr =1 */
                   7217:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7218:              break;
                   7219:            }
                   7220:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7221:            ijp=1; /* product no age */
                   7222:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7223:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7224:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7225:              if(j==Tage[ij]) { /* Product by age */
                   7226:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7227:                  if(DummyV[j]==0){
1.237     brouard  7228:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7229:                  }else{ /* quantitative */
                   7230:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7231:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7232:                  }
                   7233:                  ij++;
                   7234:                }
                   7235:              }else if(j==Tprod[ijp]) { /* */ 
                   7236:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7237:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7238:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7239:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7240:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7241:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7242:                    }else{ /* Vn is dummy and Vm is quanti */
                   7243:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7244:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7245:                    }
                   7246:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7247:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7248:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7249:                    }else{ /* Both quanti */
                   7250:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7251:                    }
                   7252:                  }
1.238     brouard  7253:                  ijp++;
1.237     brouard  7254:                }
                   7255:              } else{  /* simple covariate */
                   7256:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7257:                if(Dummy[j]==0){
                   7258:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7259:                }else{ /* quantitative */
                   7260:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7261:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7262:                }
1.237     brouard  7263:              } /* end simple */
                   7264:            } /* end j */
1.223     brouard  7265:          }else{
                   7266:            i=i-ncovmodel;
                   7267:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7268:              fprintf(ficgp," (1.");
                   7269:          }
1.227     brouard  7270:          
1.223     brouard  7271:          if(ng != 1){
                   7272:            fprintf(ficgp,")/(1");
1.227     brouard  7273:            
1.223     brouard  7274:            for(k1=1; k1 <=nlstate; k1++){ 
                   7275:              if(nagesqr==0)
                   7276:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7277:              else /* nagesqr =1 */
                   7278:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7279:               
1.223     brouard  7280:              ij=1;
                   7281:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7282:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7283:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7284:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7285:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7286:                    ij++;
                   7287:                  }
                   7288:                }
                   7289:                else
1.225     brouard  7290:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7291:              }
                   7292:              fprintf(ficgp,")");
                   7293:            }
                   7294:            fprintf(ficgp,")");
                   7295:            if(ng ==2)
                   7296:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7297:            else /* ng= 3 */
                   7298:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7299:          }else{ /* end ng <> 1 */
                   7300:            if( k !=k2) /* logit p11 is hard to draw */
                   7301:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7302:          }
                   7303:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7304:            fprintf(ficgp,",");
                   7305:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7306:            fprintf(ficgp,",");
                   7307:          i=i+ncovmodel;
                   7308:        } /* end k */
                   7309:       } /* end k2 */
                   7310:       fprintf(ficgp,"\n set out\n");
                   7311:     } /* end jk */
                   7312:   } /* end ng */
                   7313:   /* avoid: */
                   7314:   fflush(ficgp); 
1.126     brouard  7315: }  /* end gnuplot */
                   7316: 
                   7317: 
                   7318: /*************** Moving average **************/
1.219     brouard  7319: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7320:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7321:    
1.222     brouard  7322:    int i, cpt, cptcod;
                   7323:    int modcovmax =1;
                   7324:    int mobilavrange, mob;
                   7325:    int iage=0;
                   7326: 
                   7327:    double sum=0.;
                   7328:    double age;
                   7329:    double *sumnewp, *sumnewm;
                   7330:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7331:   
                   7332:   
1.225     brouard  7333:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7334:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7335: 
                   7336:    sumnewp = vector(1,ncovcombmax);
                   7337:    sumnewm = vector(1,ncovcombmax);
                   7338:    agemingood = vector(1,ncovcombmax); 
                   7339:    agemaxgood = vector(1,ncovcombmax);
                   7340: 
                   7341:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7342:      sumnewm[cptcod]=0.;
                   7343:      sumnewp[cptcod]=0.;
                   7344:      agemingood[cptcod]=0;
                   7345:      agemaxgood[cptcod]=0;
                   7346:    }
                   7347:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7348:   
                   7349:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7350:      if(mobilav==1) mobilavrange=5; /* default */
                   7351:      else mobilavrange=mobilav;
                   7352:      for (age=bage; age<=fage; age++)
                   7353:        for (i=1; i<=nlstate;i++)
                   7354:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7355:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7356:      /* We keep the original values on the extreme ages bage, fage and for 
                   7357:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7358:        we use a 5 terms etc. until the borders are no more concerned. 
                   7359:      */ 
                   7360:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7361:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7362:         for (i=1; i<=nlstate;i++){
                   7363:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7364:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7365:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7366:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7367:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7368:             }
                   7369:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7370:           }
                   7371:         }
                   7372:        }/* end age */
                   7373:      }/* end mob */
                   7374:    }else
                   7375:      return -1;
                   7376:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7377:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7378:      if(invalidvarcomb[cptcod]){
                   7379:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7380:        continue;
                   7381:      }
1.219     brouard  7382: 
1.222     brouard  7383:      agemingood[cptcod]=fage-(mob-1)/2;
                   7384:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7385:        sumnewm[cptcod]=0.;
                   7386:        for (i=1; i<=nlstate;i++){
                   7387:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7388:        }
                   7389:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7390:         agemingood[cptcod]=age;
                   7391:        }else{ /* bad */
                   7392:         for (i=1; i<=nlstate;i++){
                   7393:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7394:         } /* i */
                   7395:        } /* end bad */
                   7396:      }/* age */
                   7397:      sum=0.;
                   7398:      for (i=1; i<=nlstate;i++){
                   7399:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7400:      }
                   7401:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7402:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7403:        /* for (i=1; i<=nlstate;i++){ */
                   7404:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7405:        /* } /\* i *\/ */
                   7406:      } /* end bad */
                   7407:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7408:      /* From youngest, finding the oldest wrong */
                   7409:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7410:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7411:        sumnewm[cptcod]=0.;
                   7412:        for (i=1; i<=nlstate;i++){
                   7413:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7414:        }
                   7415:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7416:         agemaxgood[cptcod]=age;
                   7417:        }else{ /* bad */
                   7418:         for (i=1; i<=nlstate;i++){
                   7419:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7420:         } /* i */
                   7421:        } /* end bad */
                   7422:      }/* age */
                   7423:      sum=0.;
                   7424:      for (i=1; i<=nlstate;i++){
                   7425:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7426:      }
                   7427:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7428:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7429:        /* for (i=1; i<=nlstate;i++){ */
                   7430:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7431:        /* } /\* i *\/ */
                   7432:      } /* end bad */
                   7433:                
                   7434:      for (age=bage; age<=fage; age++){
1.235     brouard  7435:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7436:        sumnewp[cptcod]=0.;
                   7437:        sumnewm[cptcod]=0.;
                   7438:        for (i=1; i<=nlstate;i++){
                   7439:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7440:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7441:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7442:        }
                   7443:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7444:      }
                   7445:      /* printf("\n"); */
                   7446:      /* } */
                   7447:      /* brutal averaging */
                   7448:      for (i=1; i<=nlstate;i++){
                   7449:        for (age=1; age<=bage; age++){
                   7450:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7451:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7452:        }       
                   7453:        for (age=fage; age<=AGESUP; age++){
                   7454:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7455:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7456:        }
                   7457:      } /* end i status */
                   7458:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7459:        for (age=1; age<=AGESUP; age++){
                   7460:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7461:         mobaverage[(int)age][i][cptcod]=0.;
                   7462:        }
                   7463:      }
                   7464:    }/* end cptcod */
                   7465:    free_vector(sumnewm,1, ncovcombmax);
                   7466:    free_vector(sumnewp,1, ncovcombmax);
                   7467:    free_vector(agemaxgood,1, ncovcombmax);
                   7468:    free_vector(agemingood,1, ncovcombmax);
                   7469:    return 0;
                   7470:  }/* End movingaverage */
1.218     brouard  7471:  
1.126     brouard  7472: 
                   7473: /************** Forecasting ******************/
1.235     brouard  7474:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7475:   /* proj1, year, month, day of starting projection 
                   7476:      agemin, agemax range of age
                   7477:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7478:      anproj2 year of en of projection (same day and month as proj1).
                   7479:   */
1.235     brouard  7480:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7481:   double agec; /* generic age */
                   7482:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7483:   double *popeffectif,*popcount;
                   7484:   double ***p3mat;
1.218     brouard  7485:   /* double ***mobaverage; */
1.126     brouard  7486:   char fileresf[FILENAMELENGTH];
                   7487: 
                   7488:   agelim=AGESUP;
1.211     brouard  7489:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7490:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7491:      We still use firstpass and lastpass as another selection.
                   7492:   */
1.214     brouard  7493:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7494:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7495:  
1.201     brouard  7496:   strcpy(fileresf,"F_"); 
                   7497:   strcat(fileresf,fileresu);
1.126     brouard  7498:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7499:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7500:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7501:   }
1.235     brouard  7502:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7503:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7504: 
1.225     brouard  7505:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7506: 
                   7507: 
                   7508:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7509:   if (stepm<=12) stepsize=1;
                   7510:   if(estepm < stepm){
                   7511:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7512:   }
                   7513:   else  hstepm=estepm;   
                   7514: 
                   7515:   hstepm=hstepm/stepm; 
                   7516:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7517:                                fractional in yp1 */
                   7518:   anprojmean=yp;
                   7519:   yp2=modf((yp1*12),&yp);
                   7520:   mprojmean=yp;
                   7521:   yp1=modf((yp2*30.5),&yp);
                   7522:   jprojmean=yp;
                   7523:   if(jprojmean==0) jprojmean=1;
                   7524:   if(mprojmean==0) jprojmean=1;
                   7525: 
1.227     brouard  7526:   i1=pow(2,cptcoveff);
1.126     brouard  7527:   if (cptcovn < 1){i1=1;}
                   7528:   
                   7529:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7530:   
                   7531:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7532:   
1.126     brouard  7533: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7534:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7535:   for(k=1; k<=i1;k++){
1.253     brouard  7536:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7537:       continue;
1.227     brouard  7538:     if(invalidvarcomb[k]){
                   7539:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7540:       continue;
                   7541:     }
                   7542:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7543:     for(j=1;j<=cptcoveff;j++) {
                   7544:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7545:     }
1.235     brouard  7546:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7547:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7548:     }
1.227     brouard  7549:     fprintf(ficresf," yearproj age");
                   7550:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7551:       for(i=1; i<=nlstate;i++)               
                   7552:        fprintf(ficresf," p%d%d",i,j);
                   7553:       fprintf(ficresf," wp.%d",j);
                   7554:     }
                   7555:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7556:       fprintf(ficresf,"\n");
                   7557:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7558:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7559:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7560:        nhstepm = nhstepm/hstepm; 
                   7561:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7562:        oldm=oldms;savm=savms;
1.235     brouard  7563:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7564:        
                   7565:        for (h=0; h<=nhstepm; h++){
                   7566:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7567:            fprintf(ficresf,"\n");
                   7568:            for(j=1;j<=cptcoveff;j++) 
                   7569:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7570:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7571:          } 
                   7572:          for(j=1; j<=nlstate+ndeath;j++) {
                   7573:            ppij=0.;
                   7574:            for(i=1; i<=nlstate;i++) {
                   7575:              if (mobilav==1) 
                   7576:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7577:              else {
                   7578:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7579:              }
                   7580:              if (h*hstepm/YEARM*stepm== yearp) {
                   7581:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7582:              }
                   7583:            } /* end i */
                   7584:            if (h*hstepm/YEARM*stepm==yearp) {
                   7585:              fprintf(ficresf," %.3f", ppij);
                   7586:            }
                   7587:          }/* end j */
                   7588:        } /* end h */
                   7589:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7590:       } /* end agec */
                   7591:     } /* end yearp */
                   7592:   } /* end  k */
1.219     brouard  7593:        
1.126     brouard  7594:   fclose(ficresf);
1.215     brouard  7595:   printf("End of Computing forecasting \n");
                   7596:   fprintf(ficlog,"End of Computing forecasting\n");
                   7597: 
1.126     brouard  7598: }
                   7599: 
1.218     brouard  7600: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7601: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7602: /*   /\* back1, year, month, day of starting backection  */
                   7603: /*      agemin, agemax range of age */
                   7604: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7605: /*      anback2 year of en of backection (same day and month as back1). */
                   7606: /*   *\/ */
                   7607: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7608: /*   double agec; /\* generic age *\/ */
                   7609: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7610: /*   double *popeffectif,*popcount; */
                   7611: /*   double ***p3mat; */
                   7612: /*   /\* double ***mobaverage; *\/ */
                   7613: /*   char fileresfb[FILENAMELENGTH]; */
                   7614:        
                   7615: /*   agelim=AGESUP; */
                   7616: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7617: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7618: /*      We still use firstpass and lastpass as another selection. */
                   7619: /*   *\/ */
                   7620: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7621: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7622: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7623:        
                   7624: /*   strcpy(fileresfb,"FB_");  */
                   7625: /*   strcat(fileresfb,fileresu); */
                   7626: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7627: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7628: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7629: /*   } */
                   7630: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7631: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7632:        
1.225     brouard  7633: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7634:        
                   7635: /*   /\* if (mobilav!=0) { *\/ */
                   7636: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7637: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7638: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7639: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7640: /*   /\*   } *\/ */
                   7641: /*   /\* } *\/ */
                   7642:        
                   7643: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7644: /*   if (stepm<=12) stepsize=1; */
                   7645: /*   if(estepm < stepm){ */
                   7646: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7647: /*   } */
                   7648: /*   else  hstepm=estepm;    */
                   7649:        
                   7650: /*   hstepm=hstepm/stepm;  */
                   7651: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7652: /*                                fractional in yp1 *\/ */
                   7653: /*   anprojmean=yp; */
                   7654: /*   yp2=modf((yp1*12),&yp); */
                   7655: /*   mprojmean=yp; */
                   7656: /*   yp1=modf((yp2*30.5),&yp); */
                   7657: /*   jprojmean=yp; */
                   7658: /*   if(jprojmean==0) jprojmean=1; */
                   7659: /*   if(mprojmean==0) jprojmean=1; */
                   7660:        
1.225     brouard  7661: /*   i1=cptcoveff; */
1.218     brouard  7662: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7663:   
1.218     brouard  7664: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7665:   
1.218     brouard  7666: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7667:        
                   7668: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7669: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7670: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7671: /*       k=k+1; */
                   7672: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7673: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7674: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7675: /*       } */
                   7676: /*       fprintf(ficresfb," yearbproj age"); */
                   7677: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7678: /*                             for(i=1; i<=nlstate;i++)               */
                   7679: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7680: /*                             fprintf(ficresfb," p.%d",j); */
                   7681: /*       } */
                   7682: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7683: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7684: /*                             fprintf(ficresfb,"\n"); */
                   7685: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7686: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7687: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7688: /*                                     nhstepm = nhstepm/hstepm;  */
                   7689: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7690: /*                                     oldm=oldms;savm=savms; */
                   7691: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7692: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7693: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7694: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7695: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7696: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7697: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7698: /*                                             }  */
                   7699: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7700: /*                                                     ppij=0.; */
                   7701: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7702: /*                                                             if (mobilav==1)  */
                   7703: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7704: /*                                                             else { */
                   7705: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7706: /*                                                             } */
                   7707: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7708: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7709: /*                                                             } */
                   7710: /*                                                     } /\* end i *\/ */
                   7711: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7712: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7713: /*                                                     } */
                   7714: /*                                             }/\* end j *\/ */
                   7715: /*                                     } /\* end h *\/ */
                   7716: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7717: /*                             } /\* end agec *\/ */
                   7718: /*       } /\* end yearp *\/ */
                   7719: /*     } /\* end cptcod *\/ */
                   7720: /*   } /\* end  cptcov *\/ */
                   7721:        
                   7722: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7723:        
                   7724: /*   fclose(ficresfb); */
                   7725: /*   printf("End of Computing Back forecasting \n"); */
                   7726: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7727:        
1.218     brouard  7728: /* } */
1.217     brouard  7729: 
1.126     brouard  7730: /************** Forecasting *****not tested NB*************/
1.227     brouard  7731: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7732:   
1.227     brouard  7733: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7734: /*   int *popage; */
                   7735: /*   double calagedatem, agelim, kk1, kk2; */
                   7736: /*   double *popeffectif,*popcount; */
                   7737: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7738: /*   /\* double ***mobaverage; *\/ */
                   7739: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7740: 
1.227     brouard  7741: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7742: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7743: /*   agelim=AGESUP; */
                   7744: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7745:   
1.227     brouard  7746: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7747:   
                   7748:   
1.227     brouard  7749: /*   strcpy(filerespop,"POP_");  */
                   7750: /*   strcat(filerespop,fileresu); */
                   7751: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7752: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7753: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7754: /*   } */
                   7755: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7756: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7757: 
1.227     brouard  7758: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7759: 
1.227     brouard  7760: /*   /\* if (mobilav!=0) { *\/ */
                   7761: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7762: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7763: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7764: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7765: /*   /\*   } *\/ */
                   7766: /*   /\* } *\/ */
1.126     brouard  7767: 
1.227     brouard  7768: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7769: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7770:   
1.227     brouard  7771: /*   agelim=AGESUP; */
1.126     brouard  7772:   
1.227     brouard  7773: /*   hstepm=1; */
                   7774: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7775:        
1.227     brouard  7776: /*   if (popforecast==1) { */
                   7777: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7778: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7779: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7780: /*     }  */
                   7781: /*     popage=ivector(0,AGESUP); */
                   7782: /*     popeffectif=vector(0,AGESUP); */
                   7783: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7784:     
1.227     brouard  7785: /*     i=1;    */
                   7786: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7787:     
1.227     brouard  7788: /*     imx=i; */
                   7789: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7790: /*   } */
1.218     brouard  7791:   
1.227     brouard  7792: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7793: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7794: /*       k=k+1; */
                   7795: /*       fprintf(ficrespop,"\n#******"); */
                   7796: /*       for(j=1;j<=cptcoveff;j++) { */
                   7797: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7798: /*       } */
                   7799: /*       fprintf(ficrespop,"******\n"); */
                   7800: /*       fprintf(ficrespop,"# Age"); */
                   7801: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7802: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7803:       
1.227     brouard  7804: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7805: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7806:        
1.227     brouard  7807: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7808: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7809: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7810:          
1.227     brouard  7811: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7812: /*       oldm=oldms;savm=savms; */
                   7813: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7814:          
1.227     brouard  7815: /*       for (h=0; h<=nhstepm; h++){ */
                   7816: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7817: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7818: /*         }  */
                   7819: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7820: /*           kk1=0.;kk2=0; */
                   7821: /*           for(i=1; i<=nlstate;i++) {               */
                   7822: /*             if (mobilav==1)  */
                   7823: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7824: /*             else { */
                   7825: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7826: /*             } */
                   7827: /*           } */
                   7828: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7829: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7830: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7831: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7832: /*           } */
                   7833: /*         } */
                   7834: /*         for(i=1; i<=nlstate;i++){ */
                   7835: /*           kk1=0.; */
                   7836: /*           for(j=1; j<=nlstate;j++){ */
                   7837: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7838: /*           } */
                   7839: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7840: /*         } */
1.218     brouard  7841:            
1.227     brouard  7842: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7843: /*           for(j=1; j<=nlstate;j++)  */
                   7844: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7845: /*       } */
                   7846: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7847: /*     } */
                   7848: /*       } */
1.218     brouard  7849:       
1.227     brouard  7850: /*       /\******\/ */
1.218     brouard  7851:       
1.227     brouard  7852: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7853: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7854: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7855: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7856: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7857:          
1.227     brouard  7858: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7859: /*       oldm=oldms;savm=savms; */
                   7860: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7861: /*       for (h=0; h<=nhstepm; h++){ */
                   7862: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7863: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7864: /*         }  */
                   7865: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7866: /*           kk1=0.;kk2=0; */
                   7867: /*           for(i=1; i<=nlstate;i++) {               */
                   7868: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7869: /*           } */
                   7870: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7871: /*         } */
                   7872: /*       } */
                   7873: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7874: /*     } */
                   7875: /*       } */
                   7876: /*     }  */
                   7877: /*   } */
1.218     brouard  7878:   
1.227     brouard  7879: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7880:   
1.227     brouard  7881: /*   if (popforecast==1) { */
                   7882: /*     free_ivector(popage,0,AGESUP); */
                   7883: /*     free_vector(popeffectif,0,AGESUP); */
                   7884: /*     free_vector(popcount,0,AGESUP); */
                   7885: /*   } */
                   7886: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7887: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7888: /*   fclose(ficrespop); */
                   7889: /* } /\* End of popforecast *\/ */
1.218     brouard  7890:  
1.126     brouard  7891: int fileappend(FILE *fichier, char *optionfich)
                   7892: {
                   7893:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7894:     printf("Problem with file: %s\n", optionfich);
                   7895:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7896:     return (0);
                   7897:   }
                   7898:   fflush(fichier);
                   7899:   return (1);
                   7900: }
                   7901: 
                   7902: 
                   7903: /**************** function prwizard **********************/
                   7904: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7905: {
                   7906: 
                   7907:   /* Wizard to print covariance matrix template */
                   7908: 
1.164     brouard  7909:   char ca[32], cb[32];
                   7910:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7911:   int numlinepar;
                   7912: 
                   7913:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7914:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7915:   for(i=1; i <=nlstate; i++){
                   7916:     jj=0;
                   7917:     for(j=1; j <=nlstate+ndeath; j++){
                   7918:       if(j==i) continue;
                   7919:       jj++;
                   7920:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7921:       printf("%1d%1d",i,j);
                   7922:       fprintf(ficparo,"%1d%1d",i,j);
                   7923:       for(k=1; k<=ncovmodel;k++){
                   7924:        /*        printf(" %lf",param[i][j][k]); */
                   7925:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7926:        printf(" 0.");
                   7927:        fprintf(ficparo," 0.");
                   7928:       }
                   7929:       printf("\n");
                   7930:       fprintf(ficparo,"\n");
                   7931:     }
                   7932:   }
                   7933:   printf("# Scales (for hessian or gradient estimation)\n");
                   7934:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7935:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7936:   for(i=1; i <=nlstate; i++){
                   7937:     jj=0;
                   7938:     for(j=1; j <=nlstate+ndeath; j++){
                   7939:       if(j==i) continue;
                   7940:       jj++;
                   7941:       fprintf(ficparo,"%1d%1d",i,j);
                   7942:       printf("%1d%1d",i,j);
                   7943:       fflush(stdout);
                   7944:       for(k=1; k<=ncovmodel;k++){
                   7945:        /*      printf(" %le",delti3[i][j][k]); */
                   7946:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7947:        printf(" 0.");
                   7948:        fprintf(ficparo," 0.");
                   7949:       }
                   7950:       numlinepar++;
                   7951:       printf("\n");
                   7952:       fprintf(ficparo,"\n");
                   7953:     }
                   7954:   }
                   7955:   printf("# Covariance matrix\n");
                   7956: /* # 121 Var(a12)\n\ */
                   7957: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7958: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7959: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7960: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7961: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7962: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7963: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7964:   fflush(stdout);
                   7965:   fprintf(ficparo,"# Covariance matrix\n");
                   7966:   /* # 121 Var(a12)\n\ */
                   7967:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7968:   /* #   ...\n\ */
                   7969:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7970:   
                   7971:   for(itimes=1;itimes<=2;itimes++){
                   7972:     jj=0;
                   7973:     for(i=1; i <=nlstate; i++){
                   7974:       for(j=1; j <=nlstate+ndeath; j++){
                   7975:        if(j==i) continue;
                   7976:        for(k=1; k<=ncovmodel;k++){
                   7977:          jj++;
                   7978:          ca[0]= k+'a'-1;ca[1]='\0';
                   7979:          if(itimes==1){
                   7980:            printf("#%1d%1d%d",i,j,k);
                   7981:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7982:          }else{
                   7983:            printf("%1d%1d%d",i,j,k);
                   7984:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7985:            /*  printf(" %.5le",matcov[i][j]); */
                   7986:          }
                   7987:          ll=0;
                   7988:          for(li=1;li <=nlstate; li++){
                   7989:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   7990:              if(lj==li) continue;
                   7991:              for(lk=1;lk<=ncovmodel;lk++){
                   7992:                ll++;
                   7993:                if(ll<=jj){
                   7994:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   7995:                  if(ll<jj){
                   7996:                    if(itimes==1){
                   7997:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7998:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   7999:                    }else{
                   8000:                      printf(" 0.");
                   8001:                      fprintf(ficparo," 0.");
                   8002:                    }
                   8003:                  }else{
                   8004:                    if(itimes==1){
                   8005:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8006:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8007:                    }else{
                   8008:                      printf(" 0.");
                   8009:                      fprintf(ficparo," 0.");
                   8010:                    }
                   8011:                  }
                   8012:                }
                   8013:              } /* end lk */
                   8014:            } /* end lj */
                   8015:          } /* end li */
                   8016:          printf("\n");
                   8017:          fprintf(ficparo,"\n");
                   8018:          numlinepar++;
                   8019:        } /* end k*/
                   8020:       } /*end j */
                   8021:     } /* end i */
                   8022:   } /* end itimes */
                   8023: 
                   8024: } /* end of prwizard */
                   8025: /******************* Gompertz Likelihood ******************************/
                   8026: double gompertz(double x[])
                   8027: { 
                   8028:   double A,B,L=0.0,sump=0.,num=0.;
                   8029:   int i,n=0; /* n is the size of the sample */
                   8030: 
1.220     brouard  8031:   for (i=1;i<=imx ; i++) {
1.126     brouard  8032:     sump=sump+weight[i];
                   8033:     /*    sump=sump+1;*/
                   8034:     num=num+1;
                   8035:   }
                   8036:  
                   8037:  
                   8038:   /* for (i=0; i<=imx; i++) 
                   8039:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8040: 
                   8041:   for (i=1;i<=imx ; i++)
                   8042:     {
                   8043:       if (cens[i] == 1 && wav[i]>1)
                   8044:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8045:       
                   8046:       if (cens[i] == 0 && wav[i]>1)
                   8047:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8048:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8049:       
                   8050:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8051:       if (wav[i] > 1 ) { /* ??? */
                   8052:        L=L+A*weight[i];
                   8053:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8054:       }
                   8055:     }
                   8056: 
                   8057:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8058:  
                   8059:   return -2*L*num/sump;
                   8060: }
                   8061: 
1.136     brouard  8062: #ifdef GSL
                   8063: /******************* Gompertz_f Likelihood ******************************/
                   8064: double gompertz_f(const gsl_vector *v, void *params)
                   8065: { 
                   8066:   double A,B,LL=0.0,sump=0.,num=0.;
                   8067:   double *x= (double *) v->data;
                   8068:   int i,n=0; /* n is the size of the sample */
                   8069: 
                   8070:   for (i=0;i<=imx-1 ; i++) {
                   8071:     sump=sump+weight[i];
                   8072:     /*    sump=sump+1;*/
                   8073:     num=num+1;
                   8074:   }
                   8075:  
                   8076:  
                   8077:   /* for (i=0; i<=imx; i++) 
                   8078:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8079:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8080:   for (i=1;i<=imx ; i++)
                   8081:     {
                   8082:       if (cens[i] == 1 && wav[i]>1)
                   8083:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8084:       
                   8085:       if (cens[i] == 0 && wav[i]>1)
                   8086:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8087:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8088:       
                   8089:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8090:       if (wav[i] > 1 ) { /* ??? */
                   8091:        LL=LL+A*weight[i];
                   8092:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8093:       }
                   8094:     }
                   8095: 
                   8096:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8097:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8098:  
                   8099:   return -2*LL*num/sump;
                   8100: }
                   8101: #endif
                   8102: 
1.126     brouard  8103: /******************* Printing html file ***********/
1.201     brouard  8104: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8105:                  int lastpass, int stepm, int weightopt, char model[],\
                   8106:                  int imx,  double p[],double **matcov,double agemortsup){
                   8107:   int i,k;
                   8108: 
                   8109:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8110:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8111:   for (i=1;i<=2;i++) 
                   8112:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8113:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8114:   fprintf(fichtm,"</ul>");
                   8115: 
                   8116: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8117: 
                   8118:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8119: 
                   8120:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8121:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8122: 
                   8123:  
                   8124:   fflush(fichtm);
                   8125: }
                   8126: 
                   8127: /******************* Gnuplot file **************/
1.201     brouard  8128: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8129: 
                   8130:   char dirfileres[132],optfileres[132];
1.164     brouard  8131: 
1.126     brouard  8132:   int ng;
                   8133: 
                   8134: 
                   8135:   /*#ifdef windows */
                   8136:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8137:     /*#endif */
                   8138: 
                   8139: 
                   8140:   strcpy(dirfileres,optionfilefiname);
                   8141:   strcpy(optfileres,"vpl");
1.199     brouard  8142:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8143:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8144:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8145:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8146:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8147: 
                   8148: } 
                   8149: 
1.136     brouard  8150: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8151: {
1.126     brouard  8152: 
1.136     brouard  8153:   /*-------- data file ----------*/
                   8154:   FILE *fic;
                   8155:   char dummy[]="                         ";
1.240     brouard  8156:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8157:   int lstra;
1.136     brouard  8158:   int linei, month, year,iout;
                   8159:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8160:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8161:   char *stratrunc;
1.223     brouard  8162: 
1.240     brouard  8163:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8164:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8165: 
1.240     brouard  8166:   for(v=1; v <=ncovcol;v++){
                   8167:     DummyV[v]=0;
                   8168:     FixedV[v]=0;
                   8169:   }
                   8170:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8171:     DummyV[v]=1;
                   8172:     FixedV[v]=0;
                   8173:   }
                   8174:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8175:     DummyV[v]=0;
                   8176:     FixedV[v]=1;
                   8177:   }
                   8178:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8179:     DummyV[v]=1;
                   8180:     FixedV[v]=1;
                   8181:   }
                   8182:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8183:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8184:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8185:   }
1.126     brouard  8186: 
1.136     brouard  8187:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8188:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8189:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8190:   }
1.126     brouard  8191: 
1.136     brouard  8192:   i=1;
                   8193:   linei=0;
                   8194:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8195:     linei=linei+1;
                   8196:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8197:       if(line[j] == '\t')
                   8198:        line[j] = ' ';
                   8199:     }
                   8200:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8201:       ;
                   8202:     };
                   8203:     line[j+1]=0;  /* Trims blanks at end of line */
                   8204:     if(line[0]=='#'){
                   8205:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8206:       printf("Comment line\n%s\n",line);
                   8207:       continue;
                   8208:     }
                   8209:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8210:     strcpy(line, linetmp);
1.223     brouard  8211:     
                   8212:     /* Loops on waves */
                   8213:     for (j=maxwav;j>=1;j--){
                   8214:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8215:        cutv(stra, strb, line, ' '); 
                   8216:        if(strb[0]=='.') { /* Missing value */
                   8217:          lval=-1;
                   8218:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8219:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8220:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8221:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8222:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8223:            return 1;
                   8224:          }
                   8225:        }else{
                   8226:          errno=0;
                   8227:          /* what_kind_of_number(strb); */
                   8228:          dval=strtod(strb,&endptr); 
                   8229:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8230:          /* if(strb != endptr && *endptr == '\0') */
                   8231:          /*    dval=dlval; */
                   8232:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8233:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8234:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8235:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8236:            return 1;
                   8237:          }
                   8238:          cotqvar[j][iv][i]=dval; 
                   8239:          cotvar[j][ntv+iv][i]=dval; 
                   8240:        }
                   8241:        strcpy(line,stra);
1.223     brouard  8242:       }/* end loop ntqv */
1.225     brouard  8243:       
1.223     brouard  8244:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8245:        cutv(stra, strb, line, ' '); 
                   8246:        if(strb[0]=='.') { /* Missing value */
                   8247:          lval=-1;
                   8248:        }else{
                   8249:          errno=0;
                   8250:          lval=strtol(strb,&endptr,10); 
                   8251:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8252:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8253:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8254:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8255:            return 1;
                   8256:          }
                   8257:        }
                   8258:        if(lval <-1 || lval >1){
                   8259:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8260:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8261:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8262:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8263:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8264:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8265:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8266:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8267:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8268:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8269:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8270:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8271:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8272:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8273:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8274:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8275:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8276:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8277:          return 1;
                   8278:        }
                   8279:        cotvar[j][iv][i]=(double)(lval);
                   8280:        strcpy(line,stra);
1.223     brouard  8281:       }/* end loop ntv */
1.225     brouard  8282:       
1.223     brouard  8283:       /* Statuses  at wave */
1.137     brouard  8284:       cutv(stra, strb, line, ' '); 
1.223     brouard  8285:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8286:        lval=-1;
1.136     brouard  8287:       }else{
1.238     brouard  8288:        errno=0;
                   8289:        lval=strtol(strb,&endptr,10); 
                   8290:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8291:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8292:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8293:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8294:          return 1;
                   8295:        }
1.136     brouard  8296:       }
1.225     brouard  8297:       
1.136     brouard  8298:       s[j][i]=lval;
1.225     brouard  8299:       
1.223     brouard  8300:       /* Date of Interview */
1.136     brouard  8301:       strcpy(line,stra);
                   8302:       cutv(stra, strb,line,' ');
1.169     brouard  8303:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8304:       }
1.169     brouard  8305:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8306:        month=99;
                   8307:        year=9999;
1.136     brouard  8308:       }else{
1.225     brouard  8309:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8310:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8311:        return 1;
1.136     brouard  8312:       }
                   8313:       anint[j][i]= (double) year; 
                   8314:       mint[j][i]= (double)month; 
                   8315:       strcpy(line,stra);
1.223     brouard  8316:     } /* End loop on waves */
1.225     brouard  8317:     
1.223     brouard  8318:     /* Date of death */
1.136     brouard  8319:     cutv(stra, strb,line,' '); 
1.169     brouard  8320:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8321:     }
1.169     brouard  8322:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8323:       month=99;
                   8324:       year=9999;
                   8325:     }else{
1.141     brouard  8326:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8327:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8328:       return 1;
1.136     brouard  8329:     }
                   8330:     andc[i]=(double) year; 
                   8331:     moisdc[i]=(double) month; 
                   8332:     strcpy(line,stra);
                   8333:     
1.223     brouard  8334:     /* Date of birth */
1.136     brouard  8335:     cutv(stra, strb,line,' '); 
1.169     brouard  8336:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8337:     }
1.169     brouard  8338:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8339:       month=99;
                   8340:       year=9999;
                   8341:     }else{
1.141     brouard  8342:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8343:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8344:       return 1;
1.136     brouard  8345:     }
                   8346:     if (year==9999) {
1.141     brouard  8347:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8348:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8349:       return 1;
                   8350:       
1.136     brouard  8351:     }
                   8352:     annais[i]=(double)(year);
                   8353:     moisnais[i]=(double)(month); 
                   8354:     strcpy(line,stra);
1.225     brouard  8355:     
1.223     brouard  8356:     /* Sample weight */
1.136     brouard  8357:     cutv(stra, strb,line,' '); 
                   8358:     errno=0;
                   8359:     dval=strtod(strb,&endptr); 
                   8360:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8361:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8362:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8363:       fflush(ficlog);
                   8364:       return 1;
                   8365:     }
                   8366:     weight[i]=dval; 
                   8367:     strcpy(line,stra);
1.225     brouard  8368:     
1.223     brouard  8369:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8370:       cutv(stra, strb, line, ' '); 
                   8371:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8372:        lval=-1;
1.223     brouard  8373:       }else{
1.225     brouard  8374:        errno=0;
                   8375:        /* what_kind_of_number(strb); */
                   8376:        dval=strtod(strb,&endptr);
                   8377:        /* if(strb != endptr && *endptr == '\0') */
                   8378:        /*   dval=dlval; */
                   8379:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8380:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8381:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8382:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8383:          return 1;
                   8384:        }
                   8385:        coqvar[iv][i]=dval; 
1.226     brouard  8386:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8387:       }
                   8388:       strcpy(line,stra);
                   8389:     }/* end loop nqv */
1.136     brouard  8390:     
1.223     brouard  8391:     /* Covariate values */
1.136     brouard  8392:     for (j=ncovcol;j>=1;j--){
                   8393:       cutv(stra, strb,line,' '); 
1.223     brouard  8394:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8395:        lval=-1;
1.136     brouard  8396:       }else{
1.225     brouard  8397:        errno=0;
                   8398:        lval=strtol(strb,&endptr,10); 
                   8399:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8400:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8401:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8402:          return 1;
                   8403:        }
1.136     brouard  8404:       }
                   8405:       if(lval <-1 || lval >1){
1.225     brouard  8406:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8407:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8408:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8409:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8410:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8411:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8412:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8413:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8414:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8415:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8416:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8417:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8418:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8419:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8420:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8421:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8422:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8423:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8424:        return 1;
1.136     brouard  8425:       }
                   8426:       covar[j][i]=(double)(lval);
                   8427:       strcpy(line,stra);
                   8428:     }  
                   8429:     lstra=strlen(stra);
1.225     brouard  8430:     
1.136     brouard  8431:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8432:       stratrunc = &(stra[lstra-9]);
                   8433:       num[i]=atol(stratrunc);
                   8434:     }
                   8435:     else
                   8436:       num[i]=atol(stra);
                   8437:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8438:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8439:     
                   8440:     i=i+1;
                   8441:   } /* End loop reading  data */
1.225     brouard  8442:   
1.136     brouard  8443:   *imax=i-1; /* Number of individuals */
                   8444:   fclose(fic);
1.225     brouard  8445:   
1.136     brouard  8446:   return (0);
1.164     brouard  8447:   /* endread: */
1.225     brouard  8448:   printf("Exiting readdata: ");
                   8449:   fclose(fic);
                   8450:   return (1);
1.223     brouard  8451: }
1.126     brouard  8452: 
1.234     brouard  8453: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8454:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8455:   while (*p2 == ' ')
1.234     brouard  8456:     p2++; 
                   8457:   /* while ((*p1++ = *p2++) !=0) */
                   8458:   /*   ; */
                   8459:   /* do */
                   8460:   /*   while (*p2 == ' ') */
                   8461:   /*     p2++; */
                   8462:   /* while (*p1++ == *p2++); */
                   8463:   *stri=p2; 
1.145     brouard  8464: }
                   8465: 
1.235     brouard  8466: int decoderesult ( char resultline[], int nres)
1.230     brouard  8467: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8468: {
1.235     brouard  8469:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8470:   char resultsav[MAXLINE];
1.234     brouard  8471:   int resultmodel[MAXLINE];
                   8472:   int modelresult[MAXLINE];
1.230     brouard  8473:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8474: 
1.234     brouard  8475:   removefirstspace(&resultline);
1.233     brouard  8476:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8477: 
                   8478:   if (strstr(resultline,"v") !=0){
                   8479:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8480:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8481:     return 1;
                   8482:   }
                   8483:   trimbb(resultsav, resultline);
                   8484:   if (strlen(resultsav) >1){
                   8485:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8486:   }
1.253     brouard  8487:   if(j == 0){ /* Resultline but no = */
                   8488:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8489:     return (0);
                   8490:   }
                   8491:     
1.234     brouard  8492:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8493:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8494:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8495:   }
                   8496:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8497:     if(nbocc(resultsav,'=') >1){
                   8498:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8499:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8500:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8501:     }else
                   8502:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8503:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8504:     
1.230     brouard  8505:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8506:     Tvarsel[k]=atoi(strc);
                   8507:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8508:     /* cptcovsel++;     */
                   8509:     if (nbocc(stra,'=') >0)
                   8510:       strcpy(resultsav,stra); /* and analyzes it */
                   8511:   }
1.235     brouard  8512:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8513:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8514:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8515:       match=0;
1.236     brouard  8516:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8517:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8518:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8519:          match=1;
                   8520:          break;
                   8521:        }
                   8522:       }
                   8523:       if(match == 0){
                   8524:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8525:       }
                   8526:     }
                   8527:   }
1.235     brouard  8528:   /* Checking for missing or useless values in comparison of current model needs */
                   8529:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8530:     match=0;
1.235     brouard  8531:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8532:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8533:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8534:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8535:          ++match;
                   8536:        }
                   8537:       }
                   8538:     }
                   8539:     if(match == 0){
                   8540:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8541:     }else if(match > 1){
                   8542:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8543:     }
                   8544:   }
1.235     brouard  8545:       
1.234     brouard  8546:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8547:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8548:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8549:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8550:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8551:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8552:   /*    1 0 0 0 */
                   8553:   /*    2 1 0 0 */
                   8554:   /*    3 0 1 0 */ 
                   8555:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8556:   /*    5 0 0 1 */
                   8557:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8558:   /*    7 0 1 1 */
                   8559:   /*    8 1 1 1 */
1.237     brouard  8560:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8561:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8562:   /* V5*age V5 known which value for nres?  */
                   8563:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8564:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8565:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8566:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8567:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8568:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8569:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8570:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8571:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8572:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8573:       k4++;;
                   8574:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8575:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8576:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8577:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8578:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8579:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8580:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8581:       k4q++;;
                   8582:     }
                   8583:   }
1.234     brouard  8584:   
1.235     brouard  8585:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8586:   return (0);
                   8587: }
1.235     brouard  8588: 
1.230     brouard  8589: int decodemodel( char model[], int lastobs)
                   8590:  /**< This routine decodes the model and returns:
1.224     brouard  8591:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8592:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8593:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8594:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8595:        * - cptcovage number of covariates with age*products =2
                   8596:        * - cptcovs number of simple covariates
                   8597:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8598:        *     which is a new column after the 9 (ncovcol) variables. 
                   8599:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8600:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8601:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8602:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8603:        */
1.136     brouard  8604: {
1.238     brouard  8605:   int i, j, k, ks, v;
1.227     brouard  8606:   int  j1, k1, k2, k3, k4;
1.136     brouard  8607:   char modelsav[80];
1.145     brouard  8608:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8609:   char *strpt;
1.136     brouard  8610: 
1.145     brouard  8611:   /*removespace(model);*/
1.136     brouard  8612:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8613:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8614:     if (strstr(model,"AGE") !=0){
1.192     brouard  8615:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8616:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8617:       return 1;
                   8618:     }
1.141     brouard  8619:     if (strstr(model,"v") !=0){
                   8620:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8621:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8622:       return 1;
                   8623:     }
1.187     brouard  8624:     strcpy(modelsav,model); 
                   8625:     if ((strpt=strstr(model,"age*age")) !=0){
                   8626:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8627:       if(strpt != model){
1.234     brouard  8628:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8629:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8630:  corresponding column of parameters.\n",model);
1.234     brouard  8631:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8632:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8633:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8634:        return 1;
1.225     brouard  8635:       }
1.187     brouard  8636:       nagesqr=1;
                   8637:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8638:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8639:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8640:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8641:       else 
1.234     brouard  8642:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8643:     }else
                   8644:       nagesqr=0;
                   8645:     if (strlen(modelsav) >1){
                   8646:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8647:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8648:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8649:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8650:                     * cst, age and age*age 
                   8651:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8652:       /* including age products which are counted in cptcovage.
                   8653:        * but the covariates which are products must be treated 
                   8654:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8655:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8656:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8657:       
                   8658:       
1.187     brouard  8659:       /*   Design
                   8660:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8661:        *  <          ncovcol=8                >
                   8662:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8663:        *   k=  1    2      3       4     5       6      7        8
                   8664:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8665:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8666:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8667:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8668:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8669:        *  Tage[++cptcovage]=k
                   8670:        *       if products, new covar are created after ncovcol with k1
                   8671:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8672:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8673:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8674:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8675:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8676:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8677:        *  <          ncovcol=8                >
                   8678:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8679:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8680:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8681:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8682:        * p Tprod[1]@2={                         6, 5}
                   8683:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8684:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8685:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8686:        *How to reorganize?
                   8687:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8688:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8689:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8690:        * Struct []
                   8691:        */
1.225     brouard  8692:       
1.187     brouard  8693:       /* This loop fills the array Tvar from the string 'model'.*/
                   8694:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8695:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8696:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8697:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8698:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8699:       /*       k=1 Tvar[1]=2 (from V2) */
                   8700:       /*       k=5 Tvar[5] */
                   8701:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8702:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8703:       /*       } */
1.198     brouard  8704:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8705:       /*
                   8706:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8707:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8708:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8709:       }
1.187     brouard  8710:       cptcovage=0;
                   8711:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8712:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8713:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8714:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8715:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8716:        /*scanf("%d",i);*/
                   8717:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8718:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8719:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8720:            /* covar is not filled and then is empty */
                   8721:            cptcovprod--;
                   8722:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8723:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8724:            Typevar[k]=1;  /* 1 for age product */
                   8725:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8726:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8727:            /*printf("stre=%s ", stre);*/
                   8728:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8729:            cptcovprod--;
                   8730:            cutl(stre,strb,strc,'V');
                   8731:            Tvar[k]=atoi(stre);
                   8732:            Typevar[k]=1;  /* 1 for age product */
                   8733:            cptcovage++;
                   8734:            Tage[cptcovage]=k;
                   8735:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8736:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8737:            cptcovn++;
                   8738:            cptcovprodnoage++;k1++;
                   8739:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8740:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8741:                                                because this model-covariate is a construction we invent a new column
                   8742:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8743:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8744:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8745:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8746:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8747:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8748:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8749:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8750:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8751:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8752:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8753:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8754:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8755:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8756:            for (i=1; i<=lastobs;i++){
                   8757:              /* Computes the new covariate which is a product of
                   8758:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8759:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8760:            }
                   8761:          } /* End age is not in the model */
                   8762:        } /* End if model includes a product */
                   8763:        else { /* no more sum */
                   8764:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8765:          /*  scanf("%d",i);*/
                   8766:          cutl(strd,strc,strb,'V');
                   8767:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8768:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8769:          Tvar[k]=atoi(strd);
                   8770:          Typevar[k]=0;  /* 0 for simple covariates */
                   8771:        }
                   8772:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8773:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8774:                                  scanf("%d",i);*/
1.187     brouard  8775:       } /* end of loop + on total covariates */
                   8776:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8777:   } /* end if strlen(model == 0) */
1.136     brouard  8778:   
                   8779:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8780:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8781:   
1.136     brouard  8782:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8783:      printf("cptcovprod=%d ", cptcovprod);
                   8784:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8785:      scanf("%d ",i);*/
                   8786: 
                   8787: 
1.230     brouard  8788: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8789:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8790: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8791:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8792:    k =           1    2   3     4       5       6      7      8        9
                   8793:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8794:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8795:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8796:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8797:          Tmodelind[combination of covar]=k;
1.225     brouard  8798: */  
                   8799: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8800:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8801:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8802:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8803:   printf("Model=%s\n\
                   8804: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8805: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8806: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8807:   fprintf(ficlog,"Model=%s\n\
                   8808: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8809: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8810: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8811:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8812:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8813:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8814:       Fixed[k]= 0;
                   8815:       Dummy[k]= 0;
1.225     brouard  8816:       ncoveff++;
1.232     brouard  8817:       ncovf++;
1.234     brouard  8818:       nsd++;
                   8819:       modell[k].maintype= FTYPE;
                   8820:       TvarsD[nsd]=Tvar[k];
                   8821:       TvarsDind[nsd]=k;
                   8822:       TvarF[ncovf]=Tvar[k];
                   8823:       TvarFind[ncovf]=k;
                   8824:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8825:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8826:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8827:       Fixed[k]= 0;
                   8828:       Dummy[k]= 0;
                   8829:       ncoveff++;
                   8830:       ncovf++;
                   8831:       modell[k].maintype= FTYPE;
                   8832:       TvarF[ncovf]=Tvar[k];
                   8833:       TvarFind[ncovf]=k;
1.230     brouard  8834:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8835:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8836:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8837:       Fixed[k]= 0;
                   8838:       Dummy[k]= 1;
1.230     brouard  8839:       nqfveff++;
1.234     brouard  8840:       modell[k].maintype= FTYPE;
                   8841:       modell[k].subtype= FQ;
                   8842:       nsq++;
                   8843:       TvarsQ[nsq]=Tvar[k];
                   8844:       TvarsQind[nsq]=k;
1.232     brouard  8845:       ncovf++;
1.234     brouard  8846:       TvarF[ncovf]=Tvar[k];
                   8847:       TvarFind[ncovf]=k;
1.231     brouard  8848:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8849:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8850:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8851:       Fixed[k]= 1;
                   8852:       Dummy[k]= 0;
1.225     brouard  8853:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8854:       modell[k].maintype= VTYPE;
                   8855:       modell[k].subtype= VD;
                   8856:       nsd++;
                   8857:       TvarsD[nsd]=Tvar[k];
                   8858:       TvarsDind[nsd]=k;
                   8859:       ncovv++; /* Only simple time varying variables */
                   8860:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8861:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8862:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8863:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8864:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8865:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8866:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8867:       Fixed[k]= 1;
                   8868:       Dummy[k]= 1;
                   8869:       nqtveff++;
                   8870:       modell[k].maintype= VTYPE;
                   8871:       modell[k].subtype= VQ;
                   8872:       ncovv++; /* Only simple time varying variables */
                   8873:       nsq++;
                   8874:       TvarsQ[nsq]=Tvar[k];
                   8875:       TvarsQind[nsq]=k;
                   8876:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8877:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8878:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8879:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8880:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8881:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8882:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8883:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8884:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8885:       ncova++;
                   8886:       TvarA[ncova]=Tvar[k];
                   8887:       TvarAind[ncova]=k;
1.231     brouard  8888:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8889:        Fixed[k]= 2;
                   8890:        Dummy[k]= 2;
                   8891:        modell[k].maintype= ATYPE;
                   8892:        modell[k].subtype= APFD;
                   8893:        /* ncoveff++; */
1.227     brouard  8894:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8895:        Fixed[k]= 2;
                   8896:        Dummy[k]= 3;
                   8897:        modell[k].maintype= ATYPE;
                   8898:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8899:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8900:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8901:        Fixed[k]= 3;
                   8902:        Dummy[k]= 2;
                   8903:        modell[k].maintype= ATYPE;
                   8904:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8905:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8906:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8907:        Fixed[k]= 3;
                   8908:        Dummy[k]= 3;
                   8909:        modell[k].maintype= ATYPE;
                   8910:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8911:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8912:       }
                   8913:     }else if (Typevar[k] == 2) {  /* product without age */
                   8914:       k1=Tposprod[k];
                   8915:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8916:        if(Tvard[k1][2] <=ncovcol){
                   8917:          Fixed[k]= 1;
                   8918:          Dummy[k]= 0;
                   8919:          modell[k].maintype= FTYPE;
                   8920:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8921:          ncovf++; /* Fixed variables without age */
                   8922:          TvarF[ncovf]=Tvar[k];
                   8923:          TvarFind[ncovf]=k;
                   8924:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8925:          Fixed[k]= 0;  /* or 2 ?*/
                   8926:          Dummy[k]= 1;
                   8927:          modell[k].maintype= FTYPE;
                   8928:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8929:          ncovf++; /* Varying variables without age */
                   8930:          TvarF[ncovf]=Tvar[k];
                   8931:          TvarFind[ncovf]=k;
                   8932:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8933:          Fixed[k]= 1;
                   8934:          Dummy[k]= 0;
                   8935:          modell[k].maintype= VTYPE;
                   8936:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8937:          ncovv++; /* Varying variables without age */
                   8938:          TvarV[ncovv]=Tvar[k];
                   8939:          TvarVind[ncovv]=k;
                   8940:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8941:          Fixed[k]= 1;
                   8942:          Dummy[k]= 1;
                   8943:          modell[k].maintype= VTYPE;
                   8944:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8945:          ncovv++; /* Varying variables without age */
                   8946:          TvarV[ncovv]=Tvar[k];
                   8947:          TvarVind[ncovv]=k;
                   8948:        }
1.227     brouard  8949:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8950:        if(Tvard[k1][2] <=ncovcol){
                   8951:          Fixed[k]= 0;  /* or 2 ?*/
                   8952:          Dummy[k]= 1;
                   8953:          modell[k].maintype= FTYPE;
                   8954:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8955:          ncovf++; /* Fixed variables without age */
                   8956:          TvarF[ncovf]=Tvar[k];
                   8957:          TvarFind[ncovf]=k;
                   8958:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8959:          Fixed[k]= 1;
                   8960:          Dummy[k]= 1;
                   8961:          modell[k].maintype= VTYPE;
                   8962:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8963:          ncovv++; /* Varying variables without age */
                   8964:          TvarV[ncovv]=Tvar[k];
                   8965:          TvarVind[ncovv]=k;
                   8966:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8967:          Fixed[k]= 1;
                   8968:          Dummy[k]= 1;
                   8969:          modell[k].maintype= VTYPE;
                   8970:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8971:          ncovv++; /* Varying variables without age */
                   8972:          TvarV[ncovv]=Tvar[k];
                   8973:          TvarVind[ncovv]=k;
                   8974:          ncovv++; /* Varying variables without age */
                   8975:          TvarV[ncovv]=Tvar[k];
                   8976:          TvarVind[ncovv]=k;
                   8977:        }
1.227     brouard  8978:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8979:        if(Tvard[k1][2] <=ncovcol){
                   8980:          Fixed[k]= 1;
                   8981:          Dummy[k]= 1;
                   8982:          modell[k].maintype= VTYPE;
                   8983:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8984:          ncovv++; /* Varying variables without age */
                   8985:          TvarV[ncovv]=Tvar[k];
                   8986:          TvarVind[ncovv]=k;
                   8987:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8988:          Fixed[k]= 1;
                   8989:          Dummy[k]= 1;
                   8990:          modell[k].maintype= VTYPE;
                   8991:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   8992:          ncovv++; /* Varying variables without age */
                   8993:          TvarV[ncovv]=Tvar[k];
                   8994:          TvarVind[ncovv]=k;
                   8995:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8996:          Fixed[k]= 1;
                   8997:          Dummy[k]= 0;
                   8998:          modell[k].maintype= VTYPE;
                   8999:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9000:          ncovv++; /* Varying variables without age */
                   9001:          TvarV[ncovv]=Tvar[k];
                   9002:          TvarVind[ncovv]=k;
                   9003:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9004:          Fixed[k]= 1;
                   9005:          Dummy[k]= 1;
                   9006:          modell[k].maintype= VTYPE;
                   9007:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9008:          ncovv++; /* Varying variables without age */
                   9009:          TvarV[ncovv]=Tvar[k];
                   9010:          TvarVind[ncovv]=k;
                   9011:        }
1.227     brouard  9012:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9013:        if(Tvard[k1][2] <=ncovcol){
                   9014:          Fixed[k]= 1;
                   9015:          Dummy[k]= 1;
                   9016:          modell[k].maintype= VTYPE;
                   9017:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9018:          ncovv++; /* Varying variables without age */
                   9019:          TvarV[ncovv]=Tvar[k];
                   9020:          TvarVind[ncovv]=k;
                   9021:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9022:          Fixed[k]= 1;
                   9023:          Dummy[k]= 1;
                   9024:          modell[k].maintype= VTYPE;
                   9025:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9026:          ncovv++; /* Varying variables without age */
                   9027:          TvarV[ncovv]=Tvar[k];
                   9028:          TvarVind[ncovv]=k;
                   9029:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9030:          Fixed[k]= 1;
                   9031:          Dummy[k]= 1;
                   9032:          modell[k].maintype= VTYPE;
                   9033:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9034:          ncovv++; /* Varying variables without age */
                   9035:          TvarV[ncovv]=Tvar[k];
                   9036:          TvarVind[ncovv]=k;
                   9037:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9038:          Fixed[k]= 1;
                   9039:          Dummy[k]= 1;
                   9040:          modell[k].maintype= VTYPE;
                   9041:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9042:          ncovv++; /* Varying variables without age */
                   9043:          TvarV[ncovv]=Tvar[k];
                   9044:          TvarVind[ncovv]=k;
                   9045:        }
1.227     brouard  9046:       }else{
1.240     brouard  9047:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9048:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9049:       } /*end k1*/
1.225     brouard  9050:     }else{
1.226     brouard  9051:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9052:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9053:     }
1.227     brouard  9054:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9055:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9056:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9057:   }
                   9058:   /* Searching for doublons in the model */
                   9059:   for(k1=1; k1<= cptcovt;k1++){
                   9060:     for(k2=1; k2 <k1;k2++){
                   9061:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9062:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9063:          if(Tvar[k1]==Tvar[k2]){
                   9064:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9065:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9066:            return(1);
                   9067:          }
                   9068:        }else if (Typevar[k1] ==2){
                   9069:          k3=Tposprod[k1];
                   9070:          k4=Tposprod[k2];
                   9071:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9072:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9073:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9074:            return(1);
                   9075:          }
                   9076:        }
1.227     brouard  9077:       }
                   9078:     }
1.225     brouard  9079:   }
                   9080:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9081:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9082:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9083:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9084:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9085:   /*endread:*/
1.225     brouard  9086:   printf("Exiting decodemodel: ");
                   9087:   return (1);
1.136     brouard  9088: }
                   9089: 
1.169     brouard  9090: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9091: {/* Check ages at death */
1.136     brouard  9092:   int i, m;
1.218     brouard  9093:   int firstone=0;
                   9094:   
1.136     brouard  9095:   for (i=1; i<=imx; i++) {
                   9096:     for(m=2; (m<= maxwav); m++) {
                   9097:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9098:        anint[m][i]=9999;
1.216     brouard  9099:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9100:          s[m][i]=-1;
1.136     brouard  9101:       }
                   9102:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.169     brouard  9103:        *nberr = *nberr + 1;
1.218     brouard  9104:        if(firstone == 0){
                   9105:          firstone=1;
                   9106:        printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\nOther similar cases in log file\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
                   9107:        }
                   9108:        fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results can be biased (%d) because status is a death state %d at wave %d. Wave dropped.\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr,s[m][i],m);
1.136     brouard  9109:        s[m][i]=-1;
                   9110:       }
                   9111:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9112:        (*nberr)++;
1.136     brouard  9113:        printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
                   9114:        fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
                   9115:        s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
                   9116:       }
                   9117:     }
                   9118:   }
                   9119: 
                   9120:   for (i=1; i<=imx; i++)  {
                   9121:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9122:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9123:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9124:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9125:          if(agedc[i]>0){
                   9126:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9127:              agev[m][i]=agedc[i];
1.214     brouard  9128:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9129:            }else {
1.136     brouard  9130:              if ((int)andc[i]!=9999){
                   9131:                nbwarn++;
                   9132:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9133:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9134:                agev[m][i]=-1;
                   9135:              }
                   9136:            }
1.169     brouard  9137:          } /* agedc > 0 */
1.214     brouard  9138:        } /* end if */
1.136     brouard  9139:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9140:                                 years but with the precision of a month */
                   9141:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9142:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9143:            agev[m][i]=1;
                   9144:          else if(agev[m][i] < *agemin){ 
                   9145:            *agemin=agev[m][i];
                   9146:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9147:          }
                   9148:          else if(agev[m][i] >*agemax){
                   9149:            *agemax=agev[m][i];
1.156     brouard  9150:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9151:          }
                   9152:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9153:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9154:        } /* en if 9*/
1.136     brouard  9155:        else { /* =9 */
1.214     brouard  9156:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9157:          agev[m][i]=1;
                   9158:          s[m][i]=-1;
                   9159:        }
                   9160:       }
1.214     brouard  9161:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9162:        agev[m][i]=1;
1.214     brouard  9163:       else{
                   9164:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9165:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9166:        agev[m][i]=0;
                   9167:       }
                   9168:     } /* End for lastpass */
                   9169:   }
1.136     brouard  9170:     
                   9171:   for (i=1; i<=imx; i++)  {
                   9172:     for(m=firstpass; (m<=lastpass); m++){
                   9173:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9174:        (*nberr)++;
1.136     brouard  9175:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9176:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9177:        return 1;
                   9178:       }
                   9179:     }
                   9180:   }
                   9181: 
                   9182:   /*for (i=1; i<=imx; i++){
                   9183:   for (m=firstpass; (m<lastpass); m++){
                   9184:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9185: }
                   9186: 
                   9187: }*/
                   9188: 
                   9189: 
1.139     brouard  9190:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9191:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9192: 
                   9193:   return (0);
1.164     brouard  9194:  /* endread:*/
1.136     brouard  9195:     printf("Exiting calandcheckages: ");
                   9196:     return (1);
                   9197: }
                   9198: 
1.172     brouard  9199: #if defined(_MSC_VER)
                   9200: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9201: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9202: //#include "stdafx.h"
                   9203: //#include <stdio.h>
                   9204: //#include <tchar.h>
                   9205: //#include <windows.h>
                   9206: //#include <iostream>
                   9207: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9208: 
                   9209: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9210: 
                   9211: BOOL IsWow64()
                   9212: {
                   9213:        BOOL bIsWow64 = FALSE;
                   9214: 
                   9215:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9216:        //  (HANDLE, PBOOL);
                   9217: 
                   9218:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9219: 
                   9220:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9221:        const char funcName[] = "IsWow64Process";
                   9222:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9223:                GetProcAddress(module, funcName);
                   9224: 
                   9225:        if (NULL != fnIsWow64Process)
                   9226:        {
                   9227:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9228:                        &bIsWow64))
                   9229:                        //throw std::exception("Unknown error");
                   9230:                        printf("Unknown error\n");
                   9231:        }
                   9232:        return bIsWow64 != FALSE;
                   9233: }
                   9234: #endif
1.177     brouard  9235: 
1.191     brouard  9236: void syscompilerinfo(int logged)
1.167     brouard  9237:  {
                   9238:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9239:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9240:    /* /GS /W3 /Gy
                   9241:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9242:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9243:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9244:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9245:    */ 
                   9246:    /* 64 bits */
1.185     brouard  9247:    /*
                   9248:      /GS /W3 /Gy
                   9249:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9250:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9251:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9252:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9253:    /* Optimization are useless and O3 is slower than O2 */
                   9254:    /*
                   9255:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9256:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9257:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9258:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9259:    */
1.186     brouard  9260:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9261:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9262:       /PDB:"visual studio
                   9263:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9264:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9265:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9266:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9267:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9268:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9269:       uiAccess='false'"
                   9270:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9271:       /NOLOGO /TLBID:1
                   9272:    */
1.177     brouard  9273: #if defined __INTEL_COMPILER
1.178     brouard  9274: #if defined(__GNUC__)
                   9275:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9276: #endif
1.177     brouard  9277: #elif defined(__GNUC__) 
1.179     brouard  9278: #ifndef  __APPLE__
1.174     brouard  9279: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9280: #endif
1.177     brouard  9281:    struct utsname sysInfo;
1.178     brouard  9282:    int cross = CROSS;
                   9283:    if (cross){
                   9284:           printf("Cross-");
1.191     brouard  9285:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9286:    }
1.174     brouard  9287: #endif
                   9288: 
1.171     brouard  9289: #include <stdint.h>
1.178     brouard  9290: 
1.191     brouard  9291:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9292: #if defined(__clang__)
1.191     brouard  9293:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9294: #endif
                   9295: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9296:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9297: #endif
                   9298: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9299:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9300: #endif
                   9301: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9302:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9303: #endif
                   9304: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9305:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9306: #endif
                   9307: #if defined(_MSC_VER)
1.191     brouard  9308:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9309: #endif
                   9310: #if defined(__PGI)
1.191     brouard  9311:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9312: #endif
                   9313: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9314:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9315: #endif
1.191     brouard  9316:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9317:    
1.167     brouard  9318: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9319: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9320:     // Windows (x64 and x86)
1.191     brouard  9321:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9322: #elif __unix__ // all unices, not all compilers
                   9323:     // Unix
1.191     brouard  9324:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9325: #elif __linux__
                   9326:     // linux
1.191     brouard  9327:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9328: #elif __APPLE__
1.174     brouard  9329:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9330:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9331: #endif
                   9332: 
                   9333: /*  __MINGW32__          */
                   9334: /*  __CYGWIN__  */
                   9335: /* __MINGW64__  */
                   9336: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9337: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9338: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9339: /* _WIN64  // Defined for applications for Win64. */
                   9340: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9341: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9342: 
1.167     brouard  9343: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9344:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9345: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9346:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9347: #else
1.191     brouard  9348:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9349: #endif
                   9350: 
1.169     brouard  9351: #if defined(__GNUC__)
                   9352: # if defined(__GNUC_PATCHLEVEL__)
                   9353: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9354:                             + __GNUC_MINOR__ * 100 \
                   9355:                             + __GNUC_PATCHLEVEL__)
                   9356: # else
                   9357: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9358:                             + __GNUC_MINOR__ * 100)
                   9359: # endif
1.174     brouard  9360:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9361:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9362: 
                   9363:    if (uname(&sysInfo) != -1) {
                   9364:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9365:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9366:    }
                   9367:    else
                   9368:       perror("uname() error");
1.179     brouard  9369:    //#ifndef __INTEL_COMPILER 
                   9370: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9371:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9372:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9373: #endif
1.169     brouard  9374: #endif
1.172     brouard  9375: 
                   9376:    //   void main()
                   9377:    //   {
1.169     brouard  9378: #if defined(_MSC_VER)
1.174     brouard  9379:    if (IsWow64()){
1.191     brouard  9380:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9381:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9382:    }
                   9383:    else{
1.191     brouard  9384:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9385:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9386:    }
1.172     brouard  9387:    //     printf("\nPress Enter to continue...");
                   9388:    //     getchar();
                   9389:    //   }
                   9390: 
1.169     brouard  9391: #endif
                   9392:    
1.167     brouard  9393: 
1.219     brouard  9394: }
1.136     brouard  9395: 
1.219     brouard  9396: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9397:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9398:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9399:   /* double ftolpl = 1.e-10; */
1.180     brouard  9400:   double age, agebase, agelim;
1.203     brouard  9401:   double tot;
1.180     brouard  9402: 
1.202     brouard  9403:   strcpy(filerespl,"PL_");
                   9404:   strcat(filerespl,fileresu);
                   9405:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9406:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9407:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9408:   }
1.227     brouard  9409:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9410:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9411:   pstamp(ficrespl);
1.203     brouard  9412:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9413:   fprintf(ficrespl,"#Age ");
                   9414:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9415:   fprintf(ficrespl,"\n");
1.180     brouard  9416:   
1.219     brouard  9417:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9418: 
1.219     brouard  9419:   agebase=ageminpar;
                   9420:   agelim=agemaxpar;
1.180     brouard  9421: 
1.227     brouard  9422:   /* i1=pow(2,ncoveff); */
1.234     brouard  9423:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9424:   if (cptcovn < 1){i1=1;}
1.180     brouard  9425: 
1.238     brouard  9426:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9427:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9428:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9429:        continue;
1.235     brouard  9430: 
1.238     brouard  9431:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9432:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9433:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9434:       /* k=k+1; */
                   9435:       /* to clean */
                   9436:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9437:       fprintf(ficrespl,"#******");
                   9438:       printf("#******");
                   9439:       fprintf(ficlog,"#******");
                   9440:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9441:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9442:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9443:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9444:       }
                   9445:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9446:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9447:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9448:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9449:       }
                   9450:       fprintf(ficrespl,"******\n");
                   9451:       printf("******\n");
                   9452:       fprintf(ficlog,"******\n");
                   9453:       if(invalidvarcomb[k]){
                   9454:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9455:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9456:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9457:        continue;
                   9458:       }
1.219     brouard  9459: 
1.238     brouard  9460:       fprintf(ficrespl,"#Age ");
                   9461:       for(j=1;j<=cptcoveff;j++) {
                   9462:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9463:       }
                   9464:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9465:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9466:     
1.238     brouard  9467:       for (age=agebase; age<=agelim; age++){
                   9468:        /* for (age=agebase; age<=agebase; age++){ */
                   9469:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9470:        fprintf(ficrespl,"%.0f ",age );
                   9471:        for(j=1;j<=cptcoveff;j++)
                   9472:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9473:        tot=0.;
                   9474:        for(i=1; i<=nlstate;i++){
                   9475:          tot +=  prlim[i][i];
                   9476:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9477:        }
                   9478:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9479:       } /* Age */
                   9480:       /* was end of cptcod */
                   9481:     } /* cptcov */
                   9482:   } /* nres */
1.219     brouard  9483:   return 0;
1.180     brouard  9484: }
                   9485: 
1.218     brouard  9486: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9487:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9488:        
                   9489:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9490:    * at any age between ageminpar and agemaxpar
                   9491:         */
1.235     brouard  9492:   int i, j, k, i1, nres=0 ;
1.217     brouard  9493:   /* double ftolpl = 1.e-10; */
                   9494:   double age, agebase, agelim;
                   9495:   double tot;
1.218     brouard  9496:   /* double ***mobaverage; */
                   9497:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9498: 
                   9499:   strcpy(fileresplb,"PLB_");
                   9500:   strcat(fileresplb,fileresu);
                   9501:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9502:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9503:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9504:   }
                   9505:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9506:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9507:   pstamp(ficresplb);
                   9508:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9509:   fprintf(ficresplb,"#Age ");
                   9510:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9511:   fprintf(ficresplb,"\n");
                   9512:   
1.218     brouard  9513:   
                   9514:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9515:   
                   9516:   agebase=ageminpar;
                   9517:   agelim=agemaxpar;
                   9518:   
                   9519:   
1.227     brouard  9520:   i1=pow(2,cptcoveff);
1.218     brouard  9521:   if (cptcovn < 1){i1=1;}
1.227     brouard  9522:   
1.238     brouard  9523:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9524:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9525:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9526:        continue;
                   9527:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9528:       fprintf(ficresplb,"#******");
                   9529:       printf("#******");
                   9530:       fprintf(ficlog,"#******");
                   9531:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9532:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9533:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9534:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9535:       }
                   9536:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9537:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9538:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9539:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9540:       }
                   9541:       fprintf(ficresplb,"******\n");
                   9542:       printf("******\n");
                   9543:       fprintf(ficlog,"******\n");
                   9544:       if(invalidvarcomb[k]){
                   9545:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9546:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9547:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9548:        continue;
                   9549:       }
1.218     brouard  9550:     
1.238     brouard  9551:       fprintf(ficresplb,"#Age ");
                   9552:       for(j=1;j<=cptcoveff;j++) {
                   9553:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9554:       }
                   9555:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9556:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9557:     
                   9558:     
1.238     brouard  9559:       for (age=agebase; age<=agelim; age++){
                   9560:        /* for (age=agebase; age<=agebase; age++){ */
                   9561:        if(mobilavproj > 0){
                   9562:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9563:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9564:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9565:        }else if (mobilavproj == 0){
                   9566:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9567:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9568:          exit(1);
                   9569:        }else{
                   9570:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9571:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9572:        }
                   9573:        fprintf(ficresplb,"%.0f ",age );
                   9574:        for(j=1;j<=cptcoveff;j++)
                   9575:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9576:        tot=0.;
                   9577:        for(i=1; i<=nlstate;i++){
                   9578:          tot +=  bprlim[i][i];
                   9579:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9580:        }
                   9581:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9582:       } /* Age */
                   9583:       /* was end of cptcod */
1.255     brouard  9584:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9585:     } /* end of any combination */
                   9586:   } /* end of nres */  
1.218     brouard  9587:   /* hBijx(p, bage, fage); */
                   9588:   /* fclose(ficrespijb); */
                   9589:   
                   9590:   return 0;
1.217     brouard  9591: }
1.218     brouard  9592:  
1.180     brouard  9593: int hPijx(double *p, int bage, int fage){
                   9594:     /*------------- h Pij x at various ages ------------*/
                   9595: 
                   9596:   int stepsize;
                   9597:   int agelim;
                   9598:   int hstepm;
                   9599:   int nhstepm;
1.235     brouard  9600:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9601: 
                   9602:   double agedeb;
                   9603:   double ***p3mat;
                   9604: 
1.201     brouard  9605:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9606:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9607:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9608:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9609:     }
                   9610:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9611:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9612:   
                   9613:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9614:     /*if (stepm<=24) stepsize=2;*/
                   9615: 
                   9616:     agelim=AGESUP;
                   9617:     hstepm=stepsize*YEARM; /* Every year of age */
                   9618:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9619:                
1.180     brouard  9620:     /* hstepm=1;   aff par mois*/
                   9621:     pstamp(ficrespij);
                   9622:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9623:     i1= pow(2,cptcoveff);
1.218     brouard  9624:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9625:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9626:                /*      k=k+1;  */
1.235     brouard  9627:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9628:     for(k=1; k<=i1;k++){
1.253     brouard  9629:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9630:        continue;
1.183     brouard  9631:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9632:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9633:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9634:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9635:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9636:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9637:       }
1.183     brouard  9638:       fprintf(ficrespij,"******\n");
                   9639:       
                   9640:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9641:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9642:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9643:        
                   9644:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9645:        
1.183     brouard  9646:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9647:        oldm=oldms;savm=savms;
1.235     brouard  9648:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9649:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9650:        for(i=1; i<=nlstate;i++)
                   9651:          for(j=1; j<=nlstate+ndeath;j++)
                   9652:            fprintf(ficrespij," %1d-%1d",i,j);
                   9653:        fprintf(ficrespij,"\n");
                   9654:        for (h=0; h<=nhstepm; h++){
                   9655:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9656:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9657:          for(i=1; i<=nlstate;i++)
                   9658:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9659:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9660:          fprintf(ficrespij,"\n");
                   9661:        }
1.183     brouard  9662:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9663:        fprintf(ficrespij,"\n");
                   9664:       }
1.180     brouard  9665:       /*}*/
                   9666:     }
1.218     brouard  9667:     return 0;
1.180     brouard  9668: }
1.218     brouard  9669:  
                   9670:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9671:     /*------------- h Bij x at various ages ------------*/
                   9672: 
                   9673:   int stepsize;
1.218     brouard  9674:   /* int agelim; */
                   9675:        int ageminl;
1.217     brouard  9676:   int hstepm;
                   9677:   int nhstepm;
1.238     brouard  9678:   int h, i, i1, j, k, nres;
1.218     brouard  9679:        
1.217     brouard  9680:   double agedeb;
                   9681:   double ***p3mat;
1.218     brouard  9682:        
                   9683:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9684:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9685:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9686:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9687:   }
                   9688:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9689:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9690:   
                   9691:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9692:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9693:   
1.218     brouard  9694:   /* agelim=AGESUP; */
                   9695:   ageminl=30;
                   9696:   hstepm=stepsize*YEARM; /* Every year of age */
                   9697:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9698:   
                   9699:   /* hstepm=1;   aff par mois*/
                   9700:   pstamp(ficrespijb);
1.255     brouard  9701:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9702:   i1= pow(2,cptcoveff);
1.218     brouard  9703:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9704:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9705:   /*   k=k+1;  */
1.238     brouard  9706:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9707:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9708:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9709:        continue;
                   9710:       fprintf(ficrespijb,"\n#****** ");
                   9711:       for(j=1;j<=cptcoveff;j++)
                   9712:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9713:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9714:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9715:       }
                   9716:       fprintf(ficrespijb,"******\n");
                   9717:       if(invalidvarcomb[k]){
                   9718:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9719:        continue;
                   9720:       }
                   9721:       
                   9722:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9723:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9724:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9725:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9726:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9727:        
                   9728:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9729:        
                   9730:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9731:        /* oldm=oldms;savm=savms; */
                   9732:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9733:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9734:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  9735:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9736:        for(i=1; i<=nlstate;i++)
                   9737:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9738:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9739:        fprintf(ficrespijb,"\n");
1.238     brouard  9740:        for (h=0; h<=nhstepm; h++){
                   9741:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9742:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9743:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9744:          for(i=1; i<=nlstate;i++)
                   9745:            for(j=1; j<=nlstate+ndeath;j++)
                   9746:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9747:          fprintf(ficrespijb,"\n");
                   9748:        }
                   9749:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9750:        fprintf(ficrespijb,"\n");
                   9751:       } /* end age deb */
                   9752:     } /* end combination */
                   9753:   } /* end nres */
1.218     brouard  9754:   return 0;
                   9755:  } /*  hBijx */
1.217     brouard  9756: 
1.180     brouard  9757: 
1.136     brouard  9758: /***********************************************/
                   9759: /**************** Main Program *****************/
                   9760: /***********************************************/
                   9761: 
                   9762: int main(int argc, char *argv[])
                   9763: {
                   9764: #ifdef GSL
                   9765:   const gsl_multimin_fminimizer_type *T;
                   9766:   size_t iteri = 0, it;
                   9767:   int rval = GSL_CONTINUE;
                   9768:   int status = GSL_SUCCESS;
                   9769:   double ssval;
                   9770: #endif
                   9771:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9772:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9773:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9774:   int jj, ll, li, lj, lk;
1.136     brouard  9775:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9776:   int num_filled;
1.136     brouard  9777:   int itimes;
                   9778:   int NDIM=2;
                   9779:   int vpopbased=0;
1.235     brouard  9780:   int nres=0;
1.258   ! brouard  9781:   int endishere=0;
1.136     brouard  9782: 
1.164     brouard  9783:   char ca[32], cb[32];
1.136     brouard  9784:   /*  FILE *fichtm; *//* Html File */
                   9785:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9786:   struct stat info;
1.191     brouard  9787:   double agedeb=0.;
1.194     brouard  9788: 
                   9789:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9790:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9791: 
1.165     brouard  9792:   double fret;
1.191     brouard  9793:   double dum=0.; /* Dummy variable */
1.136     brouard  9794:   double ***p3mat;
1.218     brouard  9795:   /* double ***mobaverage; */
1.164     brouard  9796: 
                   9797:   char line[MAXLINE];
1.197     brouard  9798:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9799: 
1.234     brouard  9800:   char  modeltemp[MAXLINE];
1.230     brouard  9801:   char resultline[MAXLINE];
                   9802:   
1.136     brouard  9803:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9804:   char *tok, *val; /* pathtot */
1.136     brouard  9805:   int firstobs=1, lastobs=10;
1.195     brouard  9806:   int c,  h , cpt, c2;
1.191     brouard  9807:   int jl=0;
                   9808:   int i1, j1, jk, stepsize=0;
1.194     brouard  9809:   int count=0;
                   9810: 
1.164     brouard  9811:   int *tab; 
1.136     brouard  9812:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9813:   int backcast=0;
1.136     brouard  9814:   int mobilav=0,popforecast=0;
1.191     brouard  9815:   int hstepm=0, nhstepm=0;
1.136     brouard  9816:   int agemortsup;
                   9817:   float  sumlpop=0.;
                   9818:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9819:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9820: 
1.191     brouard  9821:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9822:   double ftolpl=FTOL;
                   9823:   double **prlim;
1.217     brouard  9824:   double **bprlim;
1.136     brouard  9825:   double ***param; /* Matrix of parameters */
1.251     brouard  9826:   double ***paramstart; /* Matrix of starting parameter values */
                   9827:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9828:   double **matcov; /* Matrix of covariance */
1.203     brouard  9829:   double **hess; /* Hessian matrix */
1.136     brouard  9830:   double ***delti3; /* Scale */
                   9831:   double *delti; /* Scale */
                   9832:   double ***eij, ***vareij;
                   9833:   double **varpl; /* Variances of prevalence limits by age */
                   9834:   double *epj, vepp;
1.164     brouard  9835: 
1.136     brouard  9836:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9837:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9838: 
1.136     brouard  9839:   double **ximort;
1.145     brouard  9840:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9841:   int *dcwave;
                   9842: 
1.164     brouard  9843:   char z[1]="c";
1.136     brouard  9844: 
                   9845:   /*char  *strt;*/
                   9846:   char strtend[80];
1.126     brouard  9847: 
1.164     brouard  9848: 
1.126     brouard  9849: /*   setlocale (LC_ALL, ""); */
                   9850: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9851: /*   textdomain (PACKAGE); */
                   9852: /*   setlocale (LC_CTYPE, ""); */
                   9853: /*   setlocale (LC_MESSAGES, ""); */
                   9854: 
                   9855:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9856:   rstart_time = time(NULL);  
                   9857:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9858:   start_time = *localtime(&rstart_time);
1.126     brouard  9859:   curr_time=start_time;
1.157     brouard  9860:   /*tml = *localtime(&start_time.tm_sec);*/
                   9861:   /* strcpy(strstart,asctime(&tml)); */
                   9862:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9863: 
                   9864: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9865: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9866: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9867: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9868: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9869: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9870: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9871: /*   strt=asctime(&tmg); */
                   9872: /*   printf("Time(after) =%s",strstart);  */
                   9873: /*  (void) time (&time_value);
                   9874: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9875: *  tm = *localtime(&time_value);
                   9876: *  strstart=asctime(&tm);
                   9877: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9878: */
                   9879: 
                   9880:   nberr=0; /* Number of errors and warnings */
                   9881:   nbwarn=0;
1.184     brouard  9882: #ifdef WIN32
                   9883:   _getcwd(pathcd, size);
                   9884: #else
1.126     brouard  9885:   getcwd(pathcd, size);
1.184     brouard  9886: #endif
1.191     brouard  9887:   syscompilerinfo(0);
1.196     brouard  9888:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9889:   if(argc <=1){
                   9890:     printf("\nEnter the parameter file name: ");
1.205     brouard  9891:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9892:       printf("ERROR Empty parameter file name\n");
                   9893:       goto end;
                   9894:     }
1.126     brouard  9895:     i=strlen(pathr);
                   9896:     if(pathr[i-1]=='\n')
                   9897:       pathr[i-1]='\0';
1.156     brouard  9898:     i=strlen(pathr);
1.205     brouard  9899:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9900:       pathr[i-1]='\0';
1.205     brouard  9901:     }
                   9902:     i=strlen(pathr);
                   9903:     if( i==0 ){
                   9904:       printf("ERROR Empty parameter file name\n");
                   9905:       goto end;
                   9906:     }
                   9907:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9908:       printf("Pathr |%s|\n",pathr);
                   9909:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9910:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9911:       strcpy (pathtot, val);
                   9912:       if(pathr[0] == '\0') break; /* Dirty */
                   9913:     }
                   9914:   }
                   9915:   else{
                   9916:     strcpy(pathtot,argv[1]);
                   9917:   }
                   9918:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9919:   /*cygwin_split_path(pathtot,path,optionfile);
                   9920:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9921:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9922: 
                   9923:   /* Split argv[0], imach program to get pathimach */
                   9924:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9925:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9926:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9927:  /*   strcpy(pathimach,argv[0]); */
                   9928:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9929:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9930:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9931: #ifdef WIN32
                   9932:   _chdir(path); /* Can be a relative path */
                   9933:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9934: #else
1.126     brouard  9935:   chdir(path); /* Can be a relative path */
1.184     brouard  9936:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9937: #endif
                   9938:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9939:   strcpy(command,"mkdir ");
                   9940:   strcat(command,optionfilefiname);
                   9941:   if((outcmd=system(command)) != 0){
1.169     brouard  9942:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9943:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9944:     /* fclose(ficlog); */
                   9945: /*     exit(1); */
                   9946:   }
                   9947: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9948: /*     perror("mkdir"); */
                   9949: /*   } */
                   9950: 
                   9951:   /*-------- arguments in the command line --------*/
                   9952: 
1.186     brouard  9953:   /* Main Log file */
1.126     brouard  9954:   strcat(filelog, optionfilefiname);
                   9955:   strcat(filelog,".log");    /* */
                   9956:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9957:     printf("Problem with logfile %s\n",filelog);
                   9958:     goto end;
                   9959:   }
                   9960:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9961:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9962:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9963:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9964:  path=%s \n\
                   9965:  optionfile=%s\n\
                   9966:  optionfilext=%s\n\
1.156     brouard  9967:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9968: 
1.197     brouard  9969:   syscompilerinfo(1);
1.167     brouard  9970: 
1.126     brouard  9971:   printf("Local time (at start):%s",strstart);
                   9972:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9973:   fflush(ficlog);
                   9974: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9975: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9976: 
                   9977:   /* */
                   9978:   strcpy(fileres,"r");
                   9979:   strcat(fileres, optionfilefiname);
1.201     brouard  9980:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9981:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9982:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9983: 
1.186     brouard  9984:   /* Main ---------arguments file --------*/
1.126     brouard  9985: 
                   9986:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  9987:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   9988:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  9989:     fflush(ficlog);
1.149     brouard  9990:     /* goto end; */
                   9991:     exit(70); 
1.126     brouard  9992:   }
                   9993: 
                   9994: 
                   9995: 
                   9996:   strcpy(filereso,"o");
1.201     brouard  9997:   strcat(filereso,fileresu);
1.126     brouard  9998:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   9999:     printf("Problem with Output resultfile: %s\n", filereso);
                   10000:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10001:     fflush(ficlog);
                   10002:     goto end;
                   10003:   }
                   10004: 
                   10005:   /* Reads comments: lines beginning with '#' */
                   10006:   numlinepar=0;
1.197     brouard  10007: 
                   10008:     /* First parameter line */
                   10009:   while(fgets(line, MAXLINE, ficpar)) {
                   10010:     /* If line starts with a # it is a comment */
                   10011:     if (line[0] == '#') {
                   10012:       numlinepar++;
                   10013:       fputs(line,stdout);
                   10014:       fputs(line,ficparo);
                   10015:       fputs(line,ficlog);
                   10016:       continue;
                   10017:     }else
                   10018:       break;
                   10019:   }
                   10020:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10021:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10022:     if (num_filled != 5) {
                   10023:       printf("Should be 5 parameters\n");
                   10024:     }
1.126     brouard  10025:     numlinepar++;
1.197     brouard  10026:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10027:   }
                   10028:   /* Second parameter line */
                   10029:   while(fgets(line, MAXLINE, ficpar)) {
                   10030:     /* If line starts with a # it is a comment */
                   10031:     if (line[0] == '#') {
                   10032:       numlinepar++;
                   10033:       fputs(line,stdout);
                   10034:       fputs(line,ficparo);
                   10035:       fputs(line,ficlog);
                   10036:       continue;
                   10037:     }else
                   10038:       break;
                   10039:   }
1.223     brouard  10040:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10041:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10042:     if (num_filled != 11) {
                   10043:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10044:       printf("but line=%s\n",line);
1.197     brouard  10045:     }
1.223     brouard  10046:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10047:   }
1.203     brouard  10048:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10049:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10050:   /* Third parameter line */
                   10051:   while(fgets(line, MAXLINE, ficpar)) {
                   10052:     /* If line starts with a # it is a comment */
                   10053:     if (line[0] == '#') {
                   10054:       numlinepar++;
                   10055:       fputs(line,stdout);
                   10056:       fputs(line,ficparo);
                   10057:       fputs(line,ficlog);
                   10058:       continue;
                   10059:     }else
                   10060:       break;
                   10061:   }
1.201     brouard  10062:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   10063:     if (num_filled == 0)
                   10064:             model[0]='\0';
                   10065:     else if (num_filled != 1){
1.197     brouard  10066:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10067:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10068:       model[0]='\0';
                   10069:       goto end;
                   10070:     }
                   10071:     else{
                   10072:       if (model[0]=='+'){
                   10073:        for(i=1; i<=strlen(model);i++)
                   10074:          modeltemp[i-1]=model[i];
1.201     brouard  10075:        strcpy(model,modeltemp); 
1.197     brouard  10076:       }
                   10077:     }
1.199     brouard  10078:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10079:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10080:   }
                   10081:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10082:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10083:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10084:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10085:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10086:   fflush(ficlog);
1.190     brouard  10087:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10088:   if(model[0]=='#'){
1.187     brouard  10089:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10090:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10091:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10092:     if(mle != -1){
                   10093:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10094:       exit(1);
                   10095:     }
                   10096:   }
1.126     brouard  10097:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10098:     ungetc(c,ficpar);
                   10099:     fgets(line, MAXLINE, ficpar);
                   10100:     numlinepar++;
1.195     brouard  10101:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10102:       z[0]=line[1];
                   10103:     }
                   10104:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10105:     fputs(line, stdout);
                   10106:     //puts(line);
1.126     brouard  10107:     fputs(line,ficparo);
                   10108:     fputs(line,ficlog);
                   10109:   }
                   10110:   ungetc(c,ficpar);
                   10111: 
                   10112:    
1.145     brouard  10113:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10114:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10115:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10116:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10117:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10118:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10119:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10120:   */
                   10121:   if (strlen(model)>1) 
1.187     brouard  10122:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10123:   else
1.187     brouard  10124:     ncovmodel=2; /* Constant and age */
1.133     brouard  10125:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10126:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10127:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10128:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10129:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10130:     fflush(stdout);
                   10131:     fclose (ficlog);
                   10132:     goto end;
                   10133:   }
1.126     brouard  10134:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10135:   delti=delti3[1][1];
                   10136:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10137:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10138: /* We could also provide initial parameters values giving by simple logistic regression 
                   10139:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10140:       /* for(i=1;i<nlstate;i++){ */
                   10141:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10142:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10143:       /* } */
1.126     brouard  10144:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10145:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10146:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10147:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10148:     fclose (ficparo);
                   10149:     fclose (ficlog);
                   10150:     goto end;
                   10151:     exit(0);
1.220     brouard  10152:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10153:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10154:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10155:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10156:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10157:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10158:     hess=matrix(1,npar,1,npar);
1.220     brouard  10159:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10160:     /* Read guessed parameters */
1.126     brouard  10161:     /* Reads comments: lines beginning with '#' */
                   10162:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10163:       ungetc(c,ficpar);
                   10164:       fgets(line, MAXLINE, ficpar);
                   10165:       numlinepar++;
1.141     brouard  10166:       fputs(line,stdout);
1.126     brouard  10167:       fputs(line,ficparo);
                   10168:       fputs(line,ficlog);
                   10169:     }
                   10170:     ungetc(c,ficpar);
                   10171:     
                   10172:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10173:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10174:     for(i=1; i <=nlstate; i++){
1.234     brouard  10175:       j=0;
1.126     brouard  10176:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10177:        if(jj==i) continue;
                   10178:        j++;
                   10179:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10180:        if ((i1 != i) || (j1 != jj)){
                   10181:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10182: It might be a problem of design; if ncovcol and the model are correct\n \
                   10183: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10184:          exit(1);
                   10185:        }
                   10186:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10187:        if(mle==1)
                   10188:          printf("%1d%1d",i,jj);
                   10189:        fprintf(ficlog,"%1d%1d",i,jj);
                   10190:        for(k=1; k<=ncovmodel;k++){
                   10191:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10192:          if(mle==1){
                   10193:            printf(" %lf",param[i][j][k]);
                   10194:            fprintf(ficlog," %lf",param[i][j][k]);
                   10195:          }
                   10196:          else
                   10197:            fprintf(ficlog," %lf",param[i][j][k]);
                   10198:          fprintf(ficparo," %lf",param[i][j][k]);
                   10199:        }
                   10200:        fscanf(ficpar,"\n");
                   10201:        numlinepar++;
                   10202:        if(mle==1)
                   10203:          printf("\n");
                   10204:        fprintf(ficlog,"\n");
                   10205:        fprintf(ficparo,"\n");
1.126     brouard  10206:       }
                   10207:     }  
                   10208:     fflush(ficlog);
1.234     brouard  10209:     
1.251     brouard  10210:     /* Reads parameters values */
1.126     brouard  10211:     p=param[1][1];
1.251     brouard  10212:     pstart=paramstart[1][1];
1.126     brouard  10213:     
                   10214:     /* Reads comments: lines beginning with '#' */
                   10215:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10216:       ungetc(c,ficpar);
                   10217:       fgets(line, MAXLINE, ficpar);
                   10218:       numlinepar++;
1.141     brouard  10219:       fputs(line,stdout);
1.126     brouard  10220:       fputs(line,ficparo);
                   10221:       fputs(line,ficlog);
                   10222:     }
                   10223:     ungetc(c,ficpar);
                   10224: 
                   10225:     for(i=1; i <=nlstate; i++){
                   10226:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10227:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10228:        if ( (i1-i) * (j1-j) != 0){
                   10229:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10230:          exit(1);
                   10231:        }
                   10232:        printf("%1d%1d",i,j);
                   10233:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10234:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10235:        for(k=1; k<=ncovmodel;k++){
                   10236:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10237:          printf(" %le",delti3[i][j][k]);
                   10238:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10239:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10240:        }
                   10241:        fscanf(ficpar,"\n");
                   10242:        numlinepar++;
                   10243:        printf("\n");
                   10244:        fprintf(ficparo,"\n");
                   10245:        fprintf(ficlog,"\n");
1.126     brouard  10246:       }
                   10247:     }
                   10248:     fflush(ficlog);
1.234     brouard  10249:     
1.145     brouard  10250:     /* Reads covariance matrix */
1.126     brouard  10251:     delti=delti3[1][1];
1.220     brouard  10252:                
                   10253:                
1.126     brouard  10254:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10255:                
1.126     brouard  10256:     /* Reads comments: lines beginning with '#' */
                   10257:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10258:       ungetc(c,ficpar);
                   10259:       fgets(line, MAXLINE, ficpar);
                   10260:       numlinepar++;
1.141     brouard  10261:       fputs(line,stdout);
1.126     brouard  10262:       fputs(line,ficparo);
                   10263:       fputs(line,ficlog);
                   10264:     }
                   10265:     ungetc(c,ficpar);
1.220     brouard  10266:                
1.126     brouard  10267:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10268:     hess=matrix(1,npar,1,npar);
1.131     brouard  10269:     for(i=1; i <=npar; i++)
                   10270:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10271:                
1.194     brouard  10272:     /* Scans npar lines */
1.126     brouard  10273:     for(i=1; i <=npar; i++){
1.226     brouard  10274:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10275:       if(count != 3){
1.226     brouard  10276:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10277: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10278: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10279:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10280: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10281: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10282:        exit(1);
1.220     brouard  10283:       }else{
1.226     brouard  10284:        if(mle==1)
                   10285:          printf("%1d%1d%d",i1,j1,jk);
                   10286:       }
                   10287:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10288:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10289:       for(j=1; j <=i; j++){
1.226     brouard  10290:        fscanf(ficpar," %le",&matcov[i][j]);
                   10291:        if(mle==1){
                   10292:          printf(" %.5le",matcov[i][j]);
                   10293:        }
                   10294:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10295:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10296:       }
                   10297:       fscanf(ficpar,"\n");
                   10298:       numlinepar++;
                   10299:       if(mle==1)
1.220     brouard  10300:                                printf("\n");
1.126     brouard  10301:       fprintf(ficlog,"\n");
                   10302:       fprintf(ficparo,"\n");
                   10303:     }
1.194     brouard  10304:     /* End of read covariance matrix npar lines */
1.126     brouard  10305:     for(i=1; i <=npar; i++)
                   10306:       for(j=i+1;j<=npar;j++)
1.226     brouard  10307:        matcov[i][j]=matcov[j][i];
1.126     brouard  10308:     
                   10309:     if(mle==1)
                   10310:       printf("\n");
                   10311:     fprintf(ficlog,"\n");
                   10312:     
                   10313:     fflush(ficlog);
                   10314:     
                   10315:     /*-------- Rewriting parameter file ----------*/
                   10316:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10317:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10318:     strcat(rfileres,".");    /* */
                   10319:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10320:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10321:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10322:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10323:     }
                   10324:     fprintf(ficres,"#%s\n",version);
                   10325:   }    /* End of mle != -3 */
1.218     brouard  10326:   
1.186     brouard  10327:   /*  Main data
                   10328:    */
1.126     brouard  10329:   n= lastobs;
                   10330:   num=lvector(1,n);
                   10331:   moisnais=vector(1,n);
                   10332:   annais=vector(1,n);
                   10333:   moisdc=vector(1,n);
                   10334:   andc=vector(1,n);
1.220     brouard  10335:   weight=vector(1,n);
1.126     brouard  10336:   agedc=vector(1,n);
                   10337:   cod=ivector(1,n);
1.220     brouard  10338:   for(i=1;i<=n;i++){
1.234     brouard  10339:     num[i]=0;
                   10340:     moisnais[i]=0;
                   10341:     annais[i]=0;
                   10342:     moisdc[i]=0;
                   10343:     andc[i]=0;
                   10344:     agedc[i]=0;
                   10345:     cod[i]=0;
                   10346:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10347:   }
1.126     brouard  10348:   mint=matrix(1,maxwav,1,n);
                   10349:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10350:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10351:   tab=ivector(1,NCOVMAX);
1.144     brouard  10352:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10353:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10354: 
1.136     brouard  10355:   /* Reads data from file datafile */
                   10356:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10357:     goto end;
                   10358: 
                   10359:   /* Calculation of the number of parameters from char model */
1.234     brouard  10360:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10361:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10362:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10363:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10364:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10365:   */
                   10366:   
                   10367:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10368:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10369:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10370:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10371:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10372:   TvarF=ivector(1,NCOVMAX); /*  */
                   10373:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10374:   TvarV=ivector(1,NCOVMAX); /*  */
                   10375:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10376:   TvarA=ivector(1,NCOVMAX); /*  */
                   10377:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10378:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10379:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10380:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10381:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10382:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10383:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10384:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10385:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10386: 
1.230     brouard  10387:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10388:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10389:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10390:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10391:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10392:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10393:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10394:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10395:   */
                   10396:   /* For model-covariate k tells which data-covariate to use but
                   10397:     because this model-covariate is a construction we invent a new column
                   10398:     ncovcol + k1
                   10399:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10400:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10401:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10402:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10403:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10404:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10405:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10406:   */
1.145     brouard  10407:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10408:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10409:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10410:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10411:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10412:                         4 covariates (3 plus signs)
                   10413:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10414:                      */  
1.230     brouard  10415:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10416:                                * individual dummy, fixed or varying:
                   10417:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10418:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10419:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10420:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10421:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10422:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10423:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10424:                                * individual quantitative, fixed or varying:
                   10425:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10426:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10427:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10428: /* Main decodemodel */
                   10429: 
1.187     brouard  10430: 
1.223     brouard  10431:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10432:     goto end;
                   10433: 
1.137     brouard  10434:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10435:     nbwarn++;
                   10436:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10437:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10438:   }
1.136     brouard  10439:     /*  if(mle==1){*/
1.137     brouard  10440:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10441:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10442:   }
                   10443: 
                   10444:     /*-calculation of age at interview from date of interview and age at death -*/
                   10445:   agev=matrix(1,maxwav,1,imx);
                   10446: 
                   10447:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10448:     goto end;
                   10449: 
1.126     brouard  10450: 
1.136     brouard  10451:   agegomp=(int)agemin;
                   10452:   free_vector(moisnais,1,n);
                   10453:   free_vector(annais,1,n);
1.126     brouard  10454:   /* free_matrix(mint,1,maxwav,1,n);
                   10455:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10456:   /* free_vector(moisdc,1,n); */
                   10457:   /* free_vector(andc,1,n); */
1.145     brouard  10458:   /* */
                   10459:   
1.126     brouard  10460:   wav=ivector(1,imx);
1.214     brouard  10461:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10462:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10463:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10464:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10465:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10466:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10467:    
                   10468:   /* Concatenates waves */
1.214     brouard  10469:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10470:      Death is a valid wave (if date is known).
                   10471:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10472:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10473:      and mw[mi+1][i]. dh depends on stepm.
                   10474:   */
                   10475: 
1.126     brouard  10476:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10477:   /* Concatenates waves */
1.145     brouard  10478:  
1.215     brouard  10479:   free_vector(moisdc,1,n);
                   10480:   free_vector(andc,1,n);
                   10481: 
1.126     brouard  10482:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10483:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10484:   ncodemax[1]=1;
1.145     brouard  10485:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10486:   cptcoveff=0;
1.220     brouard  10487:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10488:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10489:   }
                   10490:   
                   10491:   ncovcombmax=pow(2,cptcoveff);
                   10492:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10493:   for(i=1;i<ncovcombmax;i++)
                   10494:     invalidvarcomb[i]=0;
                   10495:   
1.211     brouard  10496:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10497:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10498:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10499:   
1.200     brouard  10500:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10501:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10502:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10503:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10504:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10505:    * (currently 0 or 1) in the data.
                   10506:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10507:    * corresponding modality (h,j).
                   10508:    */
                   10509: 
1.145     brouard  10510:   h=0;
                   10511:   /*if (cptcovn > 0) */
1.126     brouard  10512:   m=pow(2,cptcoveff);
                   10513:  
1.144     brouard  10514:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10515:           * For k=4 covariates, h goes from 1 to m=2**k
                   10516:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10517:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10518:           *     h\k   1     2     3     4
1.143     brouard  10519:           *______________________________  
                   10520:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10521:           *     2     2     1     1     1
                   10522:           *     3 i=2 1     2     1     1
                   10523:           *     4     2     2     1     1
                   10524:           *     5 i=3 1 i=2 1     2     1
                   10525:           *     6     2     1     2     1
                   10526:           *     7 i=4 1     2     2     1
                   10527:           *     8     2     2     2     1
1.197     brouard  10528:           *     9 i=5 1 i=3 1 i=2 1     2
                   10529:           *    10     2     1     1     2
                   10530:           *    11 i=6 1     2     1     2
                   10531:           *    12     2     2     1     2
                   10532:           *    13 i=7 1 i=4 1     2     2    
                   10533:           *    14     2     1     2     2
                   10534:           *    15 i=8 1     2     2     2
                   10535:           *    16     2     2     2     2
1.143     brouard  10536:           */
1.212     brouard  10537:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10538:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10539:      * and the value of each covariate?
                   10540:      * V1=1, V2=1, V3=2, V4=1 ?
                   10541:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10542:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10543:      * In order to get the real value in the data, we use nbcode
                   10544:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10545:      * We are keeping this crazy system in order to be able (in the future?) 
                   10546:      * to have more than 2 values (0 or 1) for a covariate.
                   10547:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10548:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10549:      *              bbbbbbbb
                   10550:      *              76543210     
                   10551:      *   h-1        00000101 (6-1=5)
1.219     brouard  10552:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10553:      *           &
                   10554:      *     1        00000001 (1)
1.219     brouard  10555:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10556:      *          +1= 00000001 =1 
1.211     brouard  10557:      *
                   10558:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10559:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10560:      *    >>k'            11
                   10561:      *          &   00000001
                   10562:      *            = 00000001
                   10563:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10564:      * Reverse h=6 and m=16?
                   10565:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10566:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10567:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10568:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10569:      * V3=decodtabm(14,3,2**4)=2
                   10570:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10571:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10572:      *          &1 000000001
                   10573:      *           = 000000001
                   10574:      *         +1= 000000010 =2
                   10575:      *                  2211
                   10576:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10577:      *                  V3=2
1.220     brouard  10578:                 * codtabm and decodtabm are identical
1.211     brouard  10579:      */
                   10580: 
1.145     brouard  10581: 
                   10582:  free_ivector(Ndum,-1,NCOVMAX);
                   10583: 
                   10584: 
1.126     brouard  10585:     
1.186     brouard  10586:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10587:   strcpy(optionfilegnuplot,optionfilefiname);
                   10588:   if(mle==-3)
1.201     brouard  10589:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10590:   strcat(optionfilegnuplot,".gp");
                   10591: 
                   10592:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10593:     printf("Problem with file %s",optionfilegnuplot);
                   10594:   }
                   10595:   else{
1.204     brouard  10596:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10597:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10598:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10599:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10600:   }
                   10601:   /*  fclose(ficgp);*/
1.186     brouard  10602: 
                   10603: 
                   10604:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10605: 
                   10606:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10607:   if(mle==-3)
1.201     brouard  10608:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10609:   strcat(optionfilehtm,".htm");
                   10610:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10611:     printf("Problem with %s \n",optionfilehtm);
                   10612:     exit(0);
1.126     brouard  10613:   }
                   10614: 
                   10615:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10616:   strcat(optionfilehtmcov,"-cov.htm");
                   10617:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10618:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10619:   }
                   10620:   else{
                   10621:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10622: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10623: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10624:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10625:   }
                   10626: 
1.213     brouard  10627:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10628: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10629: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10630: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10631: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10632: \n\
                   10633: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10634:  <ul><li><h4>Parameter files</h4>\n\
                   10635:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10636:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10637:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10638:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10639:  - Date and time at start: %s</ul>\n",\
                   10640:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10641:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10642:          fileres,fileres,\
                   10643:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10644:   fflush(fichtm);
                   10645: 
                   10646:   strcpy(pathr,path);
                   10647:   strcat(pathr,optionfilefiname);
1.184     brouard  10648: #ifdef WIN32
                   10649:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10650: #else
1.126     brouard  10651:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10652: #endif
                   10653:          
1.126     brouard  10654:   
1.220     brouard  10655:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10656:                 and for any valid combination of covariates
1.126     brouard  10657:      and prints on file fileres'p'. */
1.251     brouard  10658:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10659:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10660: 
                   10661:   fprintf(fichtm,"\n");
                   10662:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10663: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10664: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10665:          imx,agemin,agemax,jmin,jmax,jmean);
                   10666:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10667:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10668:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10669:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10670:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10671: 
1.126     brouard  10672:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10673:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10674:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10675: 
                   10676:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10677:   /* For mortality only */
1.126     brouard  10678:   if (mle==-3){
1.136     brouard  10679:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10680:     for(i=1;i<=NDIM;i++)
                   10681:       for(j=1;j<=NDIM;j++)
                   10682:        ximort[i][j]=0.;
1.186     brouard  10683:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10684:     cens=ivector(1,n);
                   10685:     ageexmed=vector(1,n);
                   10686:     agecens=vector(1,n);
                   10687:     dcwave=ivector(1,n);
1.223     brouard  10688:                
1.126     brouard  10689:     for (i=1; i<=imx; i++){
                   10690:       dcwave[i]=-1;
                   10691:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10692:        if (s[m][i]>nlstate) {
                   10693:          dcwave[i]=m;
                   10694:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10695:          break;
                   10696:        }
1.126     brouard  10697:     }
1.226     brouard  10698:     
1.126     brouard  10699:     for (i=1; i<=imx; i++) {
                   10700:       if (wav[i]>0){
1.226     brouard  10701:        ageexmed[i]=agev[mw[1][i]][i];
                   10702:        j=wav[i];
                   10703:        agecens[i]=1.; 
                   10704:        
                   10705:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10706:          agecens[i]=agev[mw[j][i]][i];
                   10707:          cens[i]= 1;
                   10708:        }else if (ageexmed[i]< 1) 
                   10709:          cens[i]= -1;
                   10710:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10711:          cens[i]=0 ;
1.126     brouard  10712:       }
                   10713:       else cens[i]=-1;
                   10714:     }
                   10715:     
                   10716:     for (i=1;i<=NDIM;i++) {
                   10717:       for (j=1;j<=NDIM;j++)
1.226     brouard  10718:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10719:     }
                   10720:     
1.145     brouard  10721:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10722:     /*printf("%lf %lf", p[1], p[2]);*/
                   10723:     
                   10724:     
1.136     brouard  10725: #ifdef GSL
                   10726:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10727: #else
1.126     brouard  10728:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10729: #endif
1.201     brouard  10730:     strcpy(filerespow,"POW-MORT_"); 
                   10731:     strcat(filerespow,fileresu);
1.126     brouard  10732:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10733:       printf("Problem with resultfile: %s\n", filerespow);
                   10734:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10735:     }
1.136     brouard  10736: #ifdef GSL
                   10737:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10738: #else
1.126     brouard  10739:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10740: #endif
1.126     brouard  10741:     /*  for (i=1;i<=nlstate;i++)
                   10742:        for(j=1;j<=nlstate+ndeath;j++)
                   10743:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10744:     */
                   10745:     fprintf(ficrespow,"\n");
1.136     brouard  10746: #ifdef GSL
                   10747:     /* gsl starts here */ 
                   10748:     T = gsl_multimin_fminimizer_nmsimplex;
                   10749:     gsl_multimin_fminimizer *sfm = NULL;
                   10750:     gsl_vector *ss, *x;
                   10751:     gsl_multimin_function minex_func;
                   10752: 
                   10753:     /* Initial vertex size vector */
                   10754:     ss = gsl_vector_alloc (NDIM);
                   10755:     
                   10756:     if (ss == NULL){
                   10757:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10758:     }
                   10759:     /* Set all step sizes to 1 */
                   10760:     gsl_vector_set_all (ss, 0.001);
                   10761: 
                   10762:     /* Starting point */
1.126     brouard  10763:     
1.136     brouard  10764:     x = gsl_vector_alloc (NDIM);
                   10765:     
                   10766:     if (x == NULL){
                   10767:       gsl_vector_free(ss);
                   10768:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10769:     }
                   10770:   
                   10771:     /* Initialize method and iterate */
                   10772:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10773:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10774:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10775:     gsl_vector_set(x, 0, p[1]);
                   10776:     gsl_vector_set(x, 1, p[2]);
                   10777: 
                   10778:     minex_func.f = &gompertz_f;
                   10779:     minex_func.n = NDIM;
                   10780:     minex_func.params = (void *)&p; /* ??? */
                   10781:     
                   10782:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10783:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10784:     
                   10785:     printf("Iterations beginning .....\n\n");
                   10786:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10787: 
                   10788:     iteri=0;
                   10789:     while (rval == GSL_CONTINUE){
                   10790:       iteri++;
                   10791:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10792:       
                   10793:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10794:       fflush(0);
                   10795:       
                   10796:       if (status) 
                   10797:         break;
                   10798:       
                   10799:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10800:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10801:       
                   10802:       if (rval == GSL_SUCCESS)
                   10803:         printf ("converged to a local maximum at\n");
                   10804:       
                   10805:       printf("%5d ", iteri);
                   10806:       for (it = 0; it < NDIM; it++){
                   10807:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10808:       }
                   10809:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10810:     }
                   10811:     
                   10812:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10813:     
                   10814:     gsl_vector_free(x); /* initial values */
                   10815:     gsl_vector_free(ss); /* inital step size */
                   10816:     for (it=0; it<NDIM; it++){
                   10817:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10818:       fprintf(ficrespow," %.12lf", p[it]);
                   10819:     }
                   10820:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10821: #endif
                   10822: #ifdef POWELL
                   10823:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10824: #endif  
1.126     brouard  10825:     fclose(ficrespow);
                   10826:     
1.203     brouard  10827:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10828: 
                   10829:     for(i=1; i <=NDIM; i++)
                   10830:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10831:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10832:     
                   10833:     printf("\nCovariance matrix\n ");
1.203     brouard  10834:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10835:     for(i=1; i <=NDIM; i++) {
                   10836:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10837:                                printf("%f ",matcov[i][j]);
                   10838:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10839:       }
1.203     brouard  10840:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10841:     }
                   10842:     
                   10843:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10844:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10845:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10846:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10847:     }
1.126     brouard  10848:     lsurv=vector(1,AGESUP);
                   10849:     lpop=vector(1,AGESUP);
                   10850:     tpop=vector(1,AGESUP);
                   10851:     lsurv[agegomp]=100000;
                   10852:     
                   10853:     for (k=agegomp;k<=AGESUP;k++) {
                   10854:       agemortsup=k;
                   10855:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10856:     }
                   10857:     
                   10858:     for (k=agegomp;k<agemortsup;k++)
                   10859:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10860:     
                   10861:     for (k=agegomp;k<agemortsup;k++){
                   10862:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10863:       sumlpop=sumlpop+lpop[k];
                   10864:     }
                   10865:     
                   10866:     tpop[agegomp]=sumlpop;
                   10867:     for (k=agegomp;k<(agemortsup-3);k++){
                   10868:       /*  tpop[k+1]=2;*/
                   10869:       tpop[k+1]=tpop[k]-lpop[k];
                   10870:     }
                   10871:     
                   10872:     
                   10873:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10874:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10875:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10876:     
                   10877:     
                   10878:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10879:                ageminpar=50;
                   10880:                agemaxpar=100;
1.194     brouard  10881:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10882:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10883: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10884: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10885:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10886: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10887: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10888:     }else{
                   10889:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10890:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10891:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10892:                }
1.201     brouard  10893:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10894:                     stepm, weightopt,\
                   10895:                     model,imx,p,matcov,agemortsup);
                   10896:     
                   10897:     free_vector(lsurv,1,AGESUP);
                   10898:     free_vector(lpop,1,AGESUP);
                   10899:     free_vector(tpop,1,AGESUP);
1.220     brouard  10900:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10901:     free_ivector(cens,1,n);
                   10902:     free_vector(agecens,1,n);
                   10903:     free_ivector(dcwave,1,n);
1.220     brouard  10904: #ifdef GSL
1.136     brouard  10905: #endif
1.186     brouard  10906:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10907:   /* Standard  */
                   10908:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10909:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10910:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10911:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10912:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10913:     for (k=1; k<=npar;k++)
                   10914:       printf(" %d %8.5f",k,p[k]);
                   10915:     printf("\n");
1.205     brouard  10916:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10917:       /* mlikeli uses func not funcone */
1.247     brouard  10918:       /* for(i=1;i<nlstate;i++){ */
                   10919:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10920:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10921:       /* } */
1.205     brouard  10922:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10923:     }
                   10924:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10925:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10926:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10927:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10928:     }
                   10929:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10930:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10931:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10932:     for (k=1; k<=npar;k++)
                   10933:       printf(" %d %8.5f",k,p[k]);
                   10934:     printf("\n");
                   10935:     
                   10936:     /*--------- results files --------------*/
1.224     brouard  10937:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10938:     
                   10939:     
                   10940:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10941:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10942:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10943:     for(i=1,jk=1; i <=nlstate; i++){
                   10944:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10945:        if (k != i) {
                   10946:          printf("%d%d ",i,k);
                   10947:          fprintf(ficlog,"%d%d ",i,k);
                   10948:          fprintf(ficres,"%1d%1d ",i,k);
                   10949:          for(j=1; j <=ncovmodel; j++){
                   10950:            printf("%12.7f ",p[jk]);
                   10951:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10952:            fprintf(ficres,"%12.7f ",p[jk]);
                   10953:            jk++; 
                   10954:          }
                   10955:          printf("\n");
                   10956:          fprintf(ficlog,"\n");
                   10957:          fprintf(ficres,"\n");
                   10958:        }
1.126     brouard  10959:       }
                   10960:     }
1.203     brouard  10961:     if(mle != 0){
                   10962:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10963:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10964:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10965:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10966:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10967:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10968:        for(k=1; k <=(nlstate+ndeath); k++){
                   10969:          if (k != i) {
                   10970:            printf("%d%d ",i,k);
                   10971:            fprintf(ficlog,"%d%d ",i,k);
                   10972:            for(j=1; j <=ncovmodel; j++){
                   10973:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10974:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10975:              jk++; 
                   10976:            }
                   10977:            printf("\n");
                   10978:            fprintf(ficlog,"\n");
                   10979:          }
                   10980:        }
1.193     brouard  10981:       }
1.203     brouard  10982:     } /* end of hesscov and Wald tests */
1.225     brouard  10983:     
1.203     brouard  10984:     /*  */
1.126     brouard  10985:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   10986:     printf("# Scales (for hessian or gradient estimation)\n");
                   10987:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   10988:     for(i=1,jk=1; i <=nlstate; i++){
                   10989:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  10990:        if (j!=i) {
                   10991:          fprintf(ficres,"%1d%1d",i,j);
                   10992:          printf("%1d%1d",i,j);
                   10993:          fprintf(ficlog,"%1d%1d",i,j);
                   10994:          for(k=1; k<=ncovmodel;k++){
                   10995:            printf(" %.5e",delti[jk]);
                   10996:            fprintf(ficlog," %.5e",delti[jk]);
                   10997:            fprintf(ficres," %.5e",delti[jk]);
                   10998:            jk++;
                   10999:          }
                   11000:          printf("\n");
                   11001:          fprintf(ficlog,"\n");
                   11002:          fprintf(ficres,"\n");
                   11003:        }
1.126     brouard  11004:       }
                   11005:     }
                   11006:     
                   11007:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11008:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11009:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11010:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11011:     /* # 121 Var(a12)\n\ */
                   11012:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11013:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11014:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11015:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11016:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11017:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11018:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11019:     
                   11020:     
                   11021:     /* Just to have a covariance matrix which will be more understandable
                   11022:        even is we still don't want to manage dictionary of variables
                   11023:     */
                   11024:     for(itimes=1;itimes<=2;itimes++){
                   11025:       jj=0;
                   11026:       for(i=1; i <=nlstate; i++){
1.225     brouard  11027:        for(j=1; j <=nlstate+ndeath; j++){
                   11028:          if(j==i) continue;
                   11029:          for(k=1; k<=ncovmodel;k++){
                   11030:            jj++;
                   11031:            ca[0]= k+'a'-1;ca[1]='\0';
                   11032:            if(itimes==1){
                   11033:              if(mle>=1)
                   11034:                printf("#%1d%1d%d",i,j,k);
                   11035:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11036:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11037:            }else{
                   11038:              if(mle>=1)
                   11039:                printf("%1d%1d%d",i,j,k);
                   11040:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11041:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11042:            }
                   11043:            ll=0;
                   11044:            for(li=1;li <=nlstate; li++){
                   11045:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11046:                if(lj==li) continue;
                   11047:                for(lk=1;lk<=ncovmodel;lk++){
                   11048:                  ll++;
                   11049:                  if(ll<=jj){
                   11050:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11051:                    if(ll<jj){
                   11052:                      if(itimes==1){
                   11053:                        if(mle>=1)
                   11054:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11055:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11056:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11057:                      }else{
                   11058:                        if(mle>=1)
                   11059:                          printf(" %.5e",matcov[jj][ll]); 
                   11060:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11061:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11062:                      }
                   11063:                    }else{
                   11064:                      if(itimes==1){
                   11065:                        if(mle>=1)
                   11066:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11067:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11068:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11069:                      }else{
                   11070:                        if(mle>=1)
                   11071:                          printf(" %.7e",matcov[jj][ll]); 
                   11072:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11073:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11074:                      }
                   11075:                    }
                   11076:                  }
                   11077:                } /* end lk */
                   11078:              } /* end lj */
                   11079:            } /* end li */
                   11080:            if(mle>=1)
                   11081:              printf("\n");
                   11082:            fprintf(ficlog,"\n");
                   11083:            fprintf(ficres,"\n");
                   11084:            numlinepar++;
                   11085:          } /* end k*/
                   11086:        } /*end j */
1.126     brouard  11087:       } /* end i */
                   11088:     } /* end itimes */
                   11089:     
                   11090:     fflush(ficlog);
                   11091:     fflush(ficres);
1.225     brouard  11092:     while(fgets(line, MAXLINE, ficpar)) {
                   11093:       /* If line starts with a # it is a comment */
                   11094:       if (line[0] == '#') {
                   11095:        numlinepar++;
                   11096:        fputs(line,stdout);
                   11097:        fputs(line,ficparo);
                   11098:        fputs(line,ficlog);
                   11099:        continue;
                   11100:       }else
                   11101:        break;
                   11102:     }
                   11103:     
1.209     brouard  11104:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11105:     /*   ungetc(c,ficpar); */
                   11106:     /*   fgets(line, MAXLINE, ficpar); */
                   11107:     /*   fputs(line,stdout); */
                   11108:     /*   fputs(line,ficparo); */
                   11109:     /* } */
                   11110:     /* ungetc(c,ficpar); */
1.126     brouard  11111:     
                   11112:     estepm=0;
1.209     brouard  11113:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11114:       
                   11115:       if (num_filled != 6) {
                   11116:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11117:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11118:        goto end;
                   11119:       }
                   11120:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11121:     }
                   11122:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11123:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11124:     
1.209     brouard  11125:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11126:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11127:     if (fage <= 2) {
                   11128:       bage = ageminpar;
                   11129:       fage = agemaxpar;
                   11130:     }
                   11131:     
                   11132:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11133:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11134:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11135:                
1.186     brouard  11136:     /* Other stuffs, more or less useful */    
1.254     brouard  11137:     while(fgets(line, MAXLINE, ficpar)) {
                   11138:       /* If line starts with a # it is a comment */
                   11139:       if (line[0] == '#') {
                   11140:        numlinepar++;
                   11141:        fputs(line,stdout);
                   11142:        fputs(line,ficparo);
                   11143:        fputs(line,ficlog);
                   11144:        continue;
                   11145:       }else
                   11146:        break;
                   11147:     }
                   11148: 
                   11149:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11150:       
                   11151:       if (num_filled != 7) {
                   11152:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11153:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11154:        goto end;
                   11155:       }
                   11156:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11157:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11158:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11159:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11160:     }
1.254     brouard  11161: 
                   11162:     while(fgets(line, MAXLINE, ficpar)) {
                   11163:       /* If line starts with a # it is a comment */
                   11164:       if (line[0] == '#') {
                   11165:        numlinepar++;
                   11166:        fputs(line,stdout);
                   11167:        fputs(line,ficparo);
                   11168:        fputs(line,ficlog);
                   11169:        continue;
                   11170:       }else
                   11171:        break;
1.126     brouard  11172:     }
                   11173:     
                   11174:     
                   11175:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11176:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11177:     
1.254     brouard  11178:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11179:       if (num_filled != 1) {
                   11180:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11181:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11182:        goto end;
                   11183:       }
                   11184:       printf("pop_based=%d\n",popbased);
                   11185:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11186:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11187:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11188:     }
                   11189:      
1.258   ! brouard  11190:     /* Results */
        !          11191:     nresult=0;
        !          11192:     do{
        !          11193:       if(!fgets(line, MAXLINE, ficpar)){
        !          11194:        endishere=1;
        !          11195:        parameterline=14;
        !          11196:       }else if (line[0] == '#') {
        !          11197:        /* If line starts with a # it is a comment */
1.254     brouard  11198:        numlinepar++;
                   11199:        fputs(line,stdout);
                   11200:        fputs(line,ficparo);
                   11201:        fputs(line,ficlog);
                   11202:        continue;
1.258   ! brouard  11203:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
        !          11204:        parameterline=11;
        !          11205:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
        !          11206:        parameterline=12;
        !          11207:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
        !          11208:        parameterline=13;
        !          11209:       else{
        !          11210:        parameterline=14;
1.254     brouard  11211:       }
1.258   ! brouard  11212:       switch (parameterline){ 
        !          11213:       case 11:
        !          11214:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
        !          11215:          if (num_filled != 8) {
        !          11216:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11217:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11218:            goto end;
        !          11219:          }
        !          11220:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
        !          11221:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
        !          11222:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
        !          11223:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
        !          11224:          /* day and month of proj2 are not used but only year anproj2.*/
        !          11225:        }
1.254     brouard  11226:        break;
1.258   ! brouard  11227:       case 12:
        !          11228:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
        !          11229:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
        !          11230:          if (num_filled != 8) {
        !          11231:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11232:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
        !          11233:            goto end;
        !          11234:          }
        !          11235:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
        !          11236:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
        !          11237:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
        !          11238:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
        !          11239:          /* day and month of proj2 are not used but only year anproj2.*/
        !          11240:        }
1.230     brouard  11241:        break;
1.258   ! brouard  11242:       case 13:
        !          11243:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
        !          11244:          if (num_filled == 0){
        !          11245:            resultline[0]='\0';
        !          11246:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
        !          11247:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
        !          11248:            break;
        !          11249:          } else if (num_filled != 1){
        !          11250:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
        !          11251:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
        !          11252:          }
        !          11253:          nresult++; /* Sum of resultlines */
        !          11254:          printf("Result %d: result=%s\n",nresult, resultline);
        !          11255:          if(nresult > MAXRESULTLINES){
        !          11256:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
        !          11257:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
        !          11258:            goto end;
        !          11259:          }
        !          11260:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
        !          11261:          fprintf(ficparo,"result: %s\n",resultline);
        !          11262:          fprintf(ficres,"result: %s\n",resultline);
        !          11263:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11264:          break;
1.258   ! brouard  11265:        case 14: 
        !          11266:          if(ncovmodel >2){
        !          11267:            printf("ERROR: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
        !          11268:            goto end;
        !          11269:          }
        !          11270:        default:
        !          11271:          nresult=1;
        !          11272:          decoderesult(".",nresult ); /* No covariate */
        !          11273:        }
        !          11274:       } /* End switch parameterline */
        !          11275:     }while(endishere==0); /* End do */
1.126     brouard  11276:     
1.230     brouard  11277:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11278:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11279:     
                   11280:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11281:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11282:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11283: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11284: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11285:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11286: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11287: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11288:     }else{
1.218     brouard  11289:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11290:     }
                   11291:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258   ! brouard  11292:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  11293:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11294:                
1.225     brouard  11295:     /*------------ free_vector  -------------*/
                   11296:     /*  chdir(path); */
1.220     brouard  11297:                
1.215     brouard  11298:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11299:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11300:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11301:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11302:     free_lvector(num,1,n);
                   11303:     free_vector(agedc,1,n);
                   11304:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11305:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11306:     fclose(ficparo);
                   11307:     fclose(ficres);
1.220     brouard  11308:                
                   11309:                
1.186     brouard  11310:     /* Other results (useful)*/
1.220     brouard  11311:                
                   11312:                
1.126     brouard  11313:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11314:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11315:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11316:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11317:     fclose(ficrespl);
                   11318: 
                   11319:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11320:     /*#include "hpijx.h"*/
                   11321:     hPijx(p, bage, fage);
1.145     brouard  11322:     fclose(ficrespij);
1.227     brouard  11323:     
1.220     brouard  11324:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11325:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11326:     k=1;
1.126     brouard  11327:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11328:     
1.219     brouard  11329:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11330:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11331:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11332:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11333:        for(k=1;k<=ncovcombmax;k++)
                   11334:          probs[i][j][k]=0.;
1.219     brouard  11335:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11336:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11337:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11338:       for(i=1;i<=AGESUP;i++)
                   11339:        for(j=1;j<=nlstate;j++)
                   11340:          for(k=1;k<=ncovcombmax;k++)
                   11341:            mobaverages[i][j][k]=0.;
1.219     brouard  11342:       mobaverage=mobaverages;
                   11343:       if (mobilav!=0) {
1.235     brouard  11344:        printf("Movingaveraging observed prevalence\n");
1.258   ! brouard  11345:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  11346:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11347:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11348:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11349:        }
1.219     brouard  11350:       }
                   11351:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11352:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11353:       else if (mobilavproj !=0) {
1.235     brouard  11354:        printf("Movingaveraging projected observed prevalence\n");
1.258   ! brouard  11355:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  11356:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11357:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11358:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11359:        }
1.219     brouard  11360:       }
                   11361:     }/* end if moving average */
1.227     brouard  11362:     
1.126     brouard  11363:     /*---------- Forecasting ------------------*/
                   11364:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11365:     if(prevfcast==1){
                   11366:       /*    if(stepm ==1){*/
1.225     brouard  11367:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11368:     }
1.217     brouard  11369:     if(backcast==1){
1.219     brouard  11370:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11371:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11372:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11373: 
                   11374:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11375: 
                   11376:       bprlim=matrix(1,nlstate,1,nlstate);
                   11377:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11378:       fclose(ficresplb);
                   11379: 
1.222     brouard  11380:       hBijx(p, bage, fage, mobaverage);
                   11381:       fclose(ficrespijb);
1.219     brouard  11382:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11383: 
                   11384:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11385:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11386:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11387:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11388:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11389:     }
1.217     brouard  11390:     
1.186     brouard  11391:  
                   11392:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11393: 
1.215     brouard  11394:     free_ivector(wav,1,imx);
                   11395:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11396:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11397:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11398:                
                   11399:                
1.127     brouard  11400:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11401:                
1.201     brouard  11402:     strcpy(filerese,"E_");
                   11403:     strcat(filerese,fileresu);
1.126     brouard  11404:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11405:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11406:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11407:     }
1.208     brouard  11408:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11409:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11410: 
                   11411:     pstamp(ficreseij);
1.219     brouard  11412:                
1.235     brouard  11413:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11414:     if (cptcovn < 1){i1=1;}
                   11415:     
                   11416:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11417:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11418:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11419:        continue;
1.219     brouard  11420:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11421:       printf("\n#****** ");
1.225     brouard  11422:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11423:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11424:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11425:       }
                   11426:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11427:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11428:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11429:       }
                   11430:       fprintf(ficreseij,"******\n");
1.235     brouard  11431:       printf("******\n");
1.219     brouard  11432:       
                   11433:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11434:       oldm=oldms;savm=savms;
1.235     brouard  11435:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11436:       
1.219     brouard  11437:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11438:     }
                   11439:     fclose(ficreseij);
1.208     brouard  11440:     printf("done evsij\n");fflush(stdout);
                   11441:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11442:                
1.227     brouard  11443:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11444:                
                   11445:                
1.201     brouard  11446:     strcpy(filerest,"T_");
                   11447:     strcat(filerest,fileresu);
1.127     brouard  11448:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11449:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11450:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11451:     }
1.208     brouard  11452:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11453:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11454:                
1.126     brouard  11455: 
1.201     brouard  11456:     strcpy(fileresstde,"STDE_");
                   11457:     strcat(fileresstde,fileresu);
1.126     brouard  11458:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11459:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11460:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11461:     }
1.227     brouard  11462:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11463:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11464: 
1.201     brouard  11465:     strcpy(filerescve,"CVE_");
                   11466:     strcat(filerescve,fileresu);
1.126     brouard  11467:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11468:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11469:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11470:     }
1.227     brouard  11471:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11472:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11473: 
1.201     brouard  11474:     strcpy(fileresv,"V_");
                   11475:     strcat(fileresv,fileresu);
1.126     brouard  11476:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11477:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11478:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11479:     }
1.227     brouard  11480:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11481:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11482: 
1.145     brouard  11483:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11484:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11485:           
1.235     brouard  11486:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11487:     if (cptcovn < 1){i1=1;}
                   11488:     
                   11489:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11490:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11491:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11492:        continue;
1.242     brouard  11493:       printf("\n#****** Result for:");
                   11494:       fprintf(ficrest,"\n#****** Result for:");
                   11495:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11496:       for(j=1;j<=cptcoveff;j++){ 
                   11497:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11498:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11499:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11500:       }
1.235     brouard  11501:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11502:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11503:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11504:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11505:       }        
1.208     brouard  11506:       fprintf(ficrest,"******\n");
1.227     brouard  11507:       fprintf(ficlog,"******\n");
                   11508:       printf("******\n");
1.208     brouard  11509:       
                   11510:       fprintf(ficresstdeij,"\n#****** ");
                   11511:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11512:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11513:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11514:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11515:       }
1.235     brouard  11516:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11517:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11518:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11519:       }        
1.208     brouard  11520:       fprintf(ficresstdeij,"******\n");
                   11521:       fprintf(ficrescveij,"******\n");
                   11522:       
                   11523:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11524:       /* pstamp(ficresvij); */
1.225     brouard  11525:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11526:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11527:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11528:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11529:       }        
1.208     brouard  11530:       fprintf(ficresvij,"******\n");
                   11531:       
                   11532:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11533:       oldm=oldms;savm=savms;
1.235     brouard  11534:       printf(" cvevsij ");
                   11535:       fprintf(ficlog, " cvevsij ");
                   11536:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11537:       printf(" end cvevsij \n ");
                   11538:       fprintf(ficlog, " end cvevsij \n ");
                   11539:       
                   11540:       /*
                   11541:        */
                   11542:       /* goto endfree; */
                   11543:       
                   11544:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11545:       pstamp(ficrest);
                   11546:       
                   11547:       
                   11548:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11549:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11550:        cptcod= 0; /* To be deleted */
                   11551:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11552:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11553:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11554:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11555:        if(vpopbased==1)
                   11556:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11557:        else
                   11558:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11559:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11560:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11561:        fprintf(ficrest,"\n");
                   11562:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11563:        epj=vector(1,nlstate+1);
                   11564:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11565:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11566:        for(age=bage; age <=fage ;age++){
1.235     brouard  11567:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11568:          if (vpopbased==1) {
                   11569:            if(mobilav ==0){
                   11570:              for(i=1; i<=nlstate;i++)
                   11571:                prlim[i][i]=probs[(int)age][i][k];
                   11572:            }else{ /* mobilav */ 
                   11573:              for(i=1; i<=nlstate;i++)
                   11574:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11575:            }
                   11576:          }
1.219     brouard  11577:          
1.227     brouard  11578:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11579:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11580:          /* printf(" age %4.0f ",age); */
                   11581:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11582:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11583:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11584:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11585:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11586:            }
                   11587:            epj[nlstate+1] +=epj[j];
                   11588:          }
                   11589:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11590:          
1.227     brouard  11591:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11592:            for(j=1;j <=nlstate;j++)
                   11593:              vepp += vareij[i][j][(int)age];
                   11594:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11595:          for(j=1;j <=nlstate;j++){
                   11596:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11597:          }
                   11598:          fprintf(ficrest,"\n");
                   11599:        }
1.208     brouard  11600:       } /* End vpopbased */
                   11601:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11602:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11603:       free_vector(epj,1,nlstate+1);
1.235     brouard  11604:       printf("done selection\n");fflush(stdout);
                   11605:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11606:       
1.145     brouard  11607:       /*}*/
1.235     brouard  11608:     } /* End k selection */
1.227     brouard  11609: 
                   11610:     printf("done State-specific expectancies\n");fflush(stdout);
                   11611:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11612: 
1.126     brouard  11613:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11614:     
1.201     brouard  11615:     strcpy(fileresvpl,"VPL_");
                   11616:     strcat(fileresvpl,fileresu);
1.126     brouard  11617:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11618:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11619:       exit(0);
                   11620:     }
1.208     brouard  11621:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11622:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11623:     
1.145     brouard  11624:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11625:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11626:     
1.235     brouard  11627:     i1=pow(2,cptcoveff);
                   11628:     if (cptcovn < 1){i1=1;}
                   11629: 
                   11630:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11631:     for(k=1; k<=i1;k++){
1.253     brouard  11632:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11633:        continue;
1.227     brouard  11634:       fprintf(ficresvpl,"\n#****** ");
                   11635:       printf("\n#****** ");
                   11636:       fprintf(ficlog,"\n#****** ");
                   11637:       for(j=1;j<=cptcoveff;j++) {
                   11638:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11639:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11640:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11641:       }
1.235     brouard  11642:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11643:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11644:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11645:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11646:       }        
1.227     brouard  11647:       fprintf(ficresvpl,"******\n");
                   11648:       printf("******\n");
                   11649:       fprintf(ficlog,"******\n");
                   11650:       
                   11651:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11652:       oldm=oldms;savm=savms;
1.235     brouard  11653:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11654:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11655:       /*}*/
1.126     brouard  11656:     }
1.227     brouard  11657:     
1.126     brouard  11658:     fclose(ficresvpl);
1.208     brouard  11659:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11660:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11661:     
                   11662:     free_vector(weight,1,n);
                   11663:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11664:     free_imatrix(s,1,maxwav+1,1,n);
                   11665:     free_matrix(anint,1,maxwav,1,n); 
                   11666:     free_matrix(mint,1,maxwav,1,n);
                   11667:     free_ivector(cod,1,n);
                   11668:     free_ivector(tab,1,NCOVMAX);
                   11669:     fclose(ficresstdeij);
                   11670:     fclose(ficrescveij);
                   11671:     fclose(ficresvij);
                   11672:     fclose(ficrest);
                   11673:     fclose(ficpar);
                   11674:     
                   11675:     
1.126     brouard  11676:     /*---------- End : free ----------------*/
1.219     brouard  11677:     if (mobilav!=0 ||mobilavproj !=0)
                   11678:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11679:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11680:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11681:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11682:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11683:   /* endfree:*/
                   11684:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11685:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11686:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11687:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11688:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11689:   free_matrix(coqvar,1,maxwav,1,n);
                   11690:   free_matrix(covar,0,NCOVMAX,1,n);
                   11691:   free_matrix(matcov,1,npar,1,npar);
                   11692:   free_matrix(hess,1,npar,1,npar);
                   11693:   /*free_vector(delti,1,npar);*/
                   11694:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11695:   free_matrix(agev,1,maxwav,1,imx);
                   11696:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11697:   
                   11698:   free_ivector(ncodemax,1,NCOVMAX);
                   11699:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11700:   free_ivector(Dummy,-1,NCOVMAX);
                   11701:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11702:   free_ivector(DummyV,1,NCOVMAX);
                   11703:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11704:   free_ivector(Typevar,-1,NCOVMAX);
                   11705:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11706:   free_ivector(TvarsQ,1,NCOVMAX);
                   11707:   free_ivector(TvarsQind,1,NCOVMAX);
                   11708:   free_ivector(TvarsD,1,NCOVMAX);
                   11709:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11710:   free_ivector(TvarFD,1,NCOVMAX);
                   11711:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11712:   free_ivector(TvarF,1,NCOVMAX);
                   11713:   free_ivector(TvarFind,1,NCOVMAX);
                   11714:   free_ivector(TvarV,1,NCOVMAX);
                   11715:   free_ivector(TvarVind,1,NCOVMAX);
                   11716:   free_ivector(TvarA,1,NCOVMAX);
                   11717:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11718:   free_ivector(TvarFQ,1,NCOVMAX);
                   11719:   free_ivector(TvarFQind,1,NCOVMAX);
                   11720:   free_ivector(TvarVD,1,NCOVMAX);
                   11721:   free_ivector(TvarVDind,1,NCOVMAX);
                   11722:   free_ivector(TvarVQ,1,NCOVMAX);
                   11723:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11724:   free_ivector(Tvarsel,1,NCOVMAX);
                   11725:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11726:   free_ivector(Tposprod,1,NCOVMAX);
                   11727:   free_ivector(Tprod,1,NCOVMAX);
                   11728:   free_ivector(Tvaraff,1,NCOVMAX);
                   11729:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11730:   free_ivector(Tage,1,NCOVMAX);
                   11731:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11732:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11733:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11734:   
                   11735:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11736:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11737:   fflush(fichtm);
                   11738:   fflush(ficgp);
                   11739:   
1.227     brouard  11740:   
1.126     brouard  11741:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11742:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11743:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11744:   }else{
                   11745:     printf("End of Imach\n");
                   11746:     fprintf(ficlog,"End of Imach\n");
                   11747:   }
                   11748:   printf("See log file on %s\n",filelog);
                   11749:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11750:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11751:   rend_time = time(NULL);  
                   11752:   end_time = *localtime(&rend_time);
                   11753:   /* tml = *localtime(&end_time.tm_sec); */
                   11754:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11755:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11756:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11757:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11758:   
1.157     brouard  11759:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11760:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11761:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11762:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11763: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11764:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11765:   fclose(fichtm);
                   11766:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11767:   fclose(fichtmcov);
                   11768:   fclose(ficgp);
                   11769:   fclose(ficlog);
                   11770:   /*------ End -----------*/
1.227     brouard  11771:   
                   11772:   
                   11773:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11774: #ifdef WIN32
1.227     brouard  11775:   if (_chdir(pathcd) != 0)
                   11776:     printf("Can't move to directory %s!\n",path);
                   11777:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11778: #else
1.227     brouard  11779:     if(chdir(pathcd) != 0)
                   11780:       printf("Can't move to directory %s!\n", path);
                   11781:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11782: #endif 
1.126     brouard  11783:     printf("Current directory %s!\n",pathcd);
                   11784:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11785:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11786: #ifdef _WIN32
1.126     brouard  11787:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11788: #endif
                   11789:   if(!stat(plotcmd,&info)){
1.158     brouard  11790:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11791:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11792:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11793:     }else
                   11794:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11795: #ifdef __unix
1.126     brouard  11796:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11797:     if(!stat(plotcmd,&info)){
1.158     brouard  11798:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11799:     }else
                   11800:       strcpy(pplotcmd,plotcmd);
                   11801: #endif
                   11802:   }else
                   11803:     strcpy(pplotcmd,plotcmd);
                   11804:   
                   11805:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11806:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11807:   
1.126     brouard  11808:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11809:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11810:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11811:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11812:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11813:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11814:   }
1.158     brouard  11815:   printf(" Successful, please wait...");
1.126     brouard  11816:   while (z[0] != 'q') {
                   11817:     /* chdir(path); */
1.154     brouard  11818:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11819:     scanf("%s",z);
                   11820: /*     if (z[0] == 'c') system("./imach"); */
                   11821:     if (z[0] == 'e') {
1.158     brouard  11822: #ifdef __APPLE__
1.152     brouard  11823:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11824: #elif __linux
                   11825:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11826: #else
1.152     brouard  11827:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11828: #endif
                   11829:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11830:       system(pplotcmd);
1.126     brouard  11831:     }
                   11832:     else if (z[0] == 'g') system(plotcmd);
                   11833:     else if (z[0] == 'q') exit(0);
                   11834:   }
1.227     brouard  11835: end:
1.126     brouard  11836:   while (z[0] != 'q') {
1.195     brouard  11837:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11838:     scanf("%s",z);
                   11839:   }
                   11840: }

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