Annotation of imach/src/imach.c, revision 1.261

1.261   ! brouard     1: /* $Id: imach.c,v 1.260 2017/04/04 17:46:59 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.261   ! brouard     4:   Revision 1.260  2017/04/04 17:46:59  brouard
        !             5:   Summary: Gnuplot indexations fixed (humm)
        !             6: 
1.260     brouard     7:   Revision 1.259  2017/04/04 13:01:16  brouard
                      8:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                      9: 
1.259     brouard    10:   Revision 1.258  2017/04/03 10:17:47  brouard
                     11:   Summary: Version 0.99r12
                     12: 
                     13:   Some cleanings, conformed with updated documentation.
                     14: 
1.258     brouard    15:   Revision 1.257  2017/03/29 16:53:30  brouard
                     16:   Summary: Temp
                     17: 
1.257     brouard    18:   Revision 1.256  2017/03/27 05:50:23  brouard
                     19:   Summary: Temporary
                     20: 
1.256     brouard    21:   Revision 1.255  2017/03/08 16:02:28  brouard
                     22:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     23: 
1.255     brouard    24:   Revision 1.254  2017/03/08 07:13:00  brouard
                     25:   Summary: Fixing data parameter line
                     26: 
1.254     brouard    27:   Revision 1.253  2016/12/15 11:59:41  brouard
                     28:   Summary: 0.99 in progress
                     29: 
1.253     brouard    30:   Revision 1.252  2016/09/15 21:15:37  brouard
                     31:   *** empty log message ***
                     32: 
1.252     brouard    33:   Revision 1.251  2016/09/15 15:01:13  brouard
                     34:   Summary: not working
                     35: 
1.251     brouard    36:   Revision 1.250  2016/09/08 16:07:27  brouard
                     37:   Summary: continue
                     38: 
1.250     brouard    39:   Revision 1.249  2016/09/07 17:14:18  brouard
                     40:   Summary: Starting values from frequencies
                     41: 
1.249     brouard    42:   Revision 1.248  2016/09/07 14:10:18  brouard
                     43:   *** empty log message ***
                     44: 
1.248     brouard    45:   Revision 1.247  2016/09/02 11:11:21  brouard
                     46:   *** empty log message ***
                     47: 
1.247     brouard    48:   Revision 1.246  2016/09/02 08:49:22  brouard
                     49:   *** empty log message ***
                     50: 
1.246     brouard    51:   Revision 1.245  2016/09/02 07:25:01  brouard
                     52:   *** empty log message ***
                     53: 
1.245     brouard    54:   Revision 1.244  2016/09/02 07:17:34  brouard
                     55:   *** empty log message ***
                     56: 
1.244     brouard    57:   Revision 1.243  2016/09/02 06:45:35  brouard
                     58:   *** empty log message ***
                     59: 
1.243     brouard    60:   Revision 1.242  2016/08/30 15:01:20  brouard
                     61:   Summary: Fixing a lots
                     62: 
1.242     brouard    63:   Revision 1.241  2016/08/29 17:17:25  brouard
                     64:   Summary: gnuplot problem in Back projection to fix
                     65: 
1.241     brouard    66:   Revision 1.240  2016/08/29 07:53:18  brouard
                     67:   Summary: Better
                     68: 
1.240     brouard    69:   Revision 1.239  2016/08/26 15:51:03  brouard
                     70:   Summary: Improvement in Powell output in order to copy and paste
                     71: 
                     72:   Author:
                     73: 
1.239     brouard    74:   Revision 1.238  2016/08/26 14:23:35  brouard
                     75:   Summary: Starting tests of 0.99
                     76: 
1.238     brouard    77:   Revision 1.237  2016/08/26 09:20:19  brouard
                     78:   Summary: to valgrind
                     79: 
1.237     brouard    80:   Revision 1.236  2016/08/25 10:50:18  brouard
                     81:   *** empty log message ***
                     82: 
1.236     brouard    83:   Revision 1.235  2016/08/25 06:59:23  brouard
                     84:   *** empty log message ***
                     85: 
1.235     brouard    86:   Revision 1.234  2016/08/23 16:51:20  brouard
                     87:   *** empty log message ***
                     88: 
1.234     brouard    89:   Revision 1.233  2016/08/23 07:40:50  brouard
                     90:   Summary: not working
                     91: 
1.233     brouard    92:   Revision 1.232  2016/08/22 14:20:21  brouard
                     93:   Summary: not working
                     94: 
1.232     brouard    95:   Revision 1.231  2016/08/22 07:17:15  brouard
                     96:   Summary: not working
                     97: 
1.231     brouard    98:   Revision 1.230  2016/08/22 06:55:53  brouard
                     99:   Summary: Not working
                    100: 
1.230     brouard   101:   Revision 1.229  2016/07/23 09:45:53  brouard
                    102:   Summary: Completing for func too
                    103: 
1.229     brouard   104:   Revision 1.228  2016/07/22 17:45:30  brouard
                    105:   Summary: Fixing some arrays, still debugging
                    106: 
1.227     brouard   107:   Revision 1.226  2016/07/12 18:42:34  brouard
                    108:   Summary: temp
                    109: 
1.226     brouard   110:   Revision 1.225  2016/07/12 08:40:03  brouard
                    111:   Summary: saving but not running
                    112: 
1.225     brouard   113:   Revision 1.224  2016/07/01 13:16:01  brouard
                    114:   Summary: Fixes
                    115: 
1.224     brouard   116:   Revision 1.223  2016/02/19 09:23:35  brouard
                    117:   Summary: temporary
                    118: 
1.223     brouard   119:   Revision 1.222  2016/02/17 08:14:50  brouard
                    120:   Summary: Probably last 0.98 stable version 0.98r6
                    121: 
1.222     brouard   122:   Revision 1.221  2016/02/15 23:35:36  brouard
                    123:   Summary: minor bug
                    124: 
1.220     brouard   125:   Revision 1.219  2016/02/15 00:48:12  brouard
                    126:   *** empty log message ***
                    127: 
1.219     brouard   128:   Revision 1.218  2016/02/12 11:29:23  brouard
                    129:   Summary: 0.99 Back projections
                    130: 
1.218     brouard   131:   Revision 1.217  2015/12/23 17:18:31  brouard
                    132:   Summary: Experimental backcast
                    133: 
1.217     brouard   134:   Revision 1.216  2015/12/18 17:32:11  brouard
                    135:   Summary: 0.98r4 Warning and status=-2
                    136: 
                    137:   Version 0.98r4 is now:
                    138:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    139:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    140:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    141: 
1.216     brouard   142:   Revision 1.215  2015/12/16 08:52:24  brouard
                    143:   Summary: 0.98r4 working
                    144: 
1.215     brouard   145:   Revision 1.214  2015/12/16 06:57:54  brouard
                    146:   Summary: temporary not working
                    147: 
1.214     brouard   148:   Revision 1.213  2015/12/11 18:22:17  brouard
                    149:   Summary: 0.98r4
                    150: 
1.213     brouard   151:   Revision 1.212  2015/11/21 12:47:24  brouard
                    152:   Summary: minor typo
                    153: 
1.212     brouard   154:   Revision 1.211  2015/11/21 12:41:11  brouard
                    155:   Summary: 0.98r3 with some graph of projected cross-sectional
                    156: 
                    157:   Author: Nicolas Brouard
                    158: 
1.211     brouard   159:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   160:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   161:   Summary: Adding ftolpl parameter
                    162:   Author: N Brouard
                    163: 
                    164:   We had difficulties to get smoothed confidence intervals. It was due
                    165:   to the period prevalence which wasn't computed accurately. The inner
                    166:   parameter ftolpl is now an outer parameter of the .imach parameter
                    167:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    168:   computation are long.
                    169: 
1.209     brouard   170:   Revision 1.208  2015/11/17 14:31:57  brouard
                    171:   Summary: temporary
                    172: 
1.208     brouard   173:   Revision 1.207  2015/10/27 17:36:57  brouard
                    174:   *** empty log message ***
                    175: 
1.207     brouard   176:   Revision 1.206  2015/10/24 07:14:11  brouard
                    177:   *** empty log message ***
                    178: 
1.206     brouard   179:   Revision 1.205  2015/10/23 15:50:53  brouard
                    180:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    181: 
1.205     brouard   182:   Revision 1.204  2015/10/01 16:20:26  brouard
                    183:   Summary: Some new graphs of contribution to likelihood
                    184: 
1.204     brouard   185:   Revision 1.203  2015/09/30 17:45:14  brouard
                    186:   Summary: looking at better estimation of the hessian
                    187: 
                    188:   Also a better criteria for convergence to the period prevalence And
                    189:   therefore adding the number of years needed to converge. (The
                    190:   prevalence in any alive state shold sum to one
                    191: 
1.203     brouard   192:   Revision 1.202  2015/09/22 19:45:16  brouard
                    193:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    194: 
1.202     brouard   195:   Revision 1.201  2015/09/15 17:34:58  brouard
                    196:   Summary: 0.98r0
                    197: 
                    198:   - Some new graphs like suvival functions
                    199:   - Some bugs fixed like model=1+age+V2.
                    200: 
1.201     brouard   201:   Revision 1.200  2015/09/09 16:53:55  brouard
                    202:   Summary: Big bug thanks to Flavia
                    203: 
                    204:   Even model=1+age+V2. did not work anymore
                    205: 
1.200     brouard   206:   Revision 1.199  2015/09/07 14:09:23  brouard
                    207:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    208: 
1.199     brouard   209:   Revision 1.198  2015/09/03 07:14:39  brouard
                    210:   Summary: 0.98q5 Flavia
                    211: 
1.198     brouard   212:   Revision 1.197  2015/09/01 18:24:39  brouard
                    213:   *** empty log message ***
                    214: 
1.197     brouard   215:   Revision 1.196  2015/08/18 23:17:52  brouard
                    216:   Summary: 0.98q5
                    217: 
1.196     brouard   218:   Revision 1.195  2015/08/18 16:28:39  brouard
                    219:   Summary: Adding a hack for testing purpose
                    220: 
                    221:   After reading the title, ftol and model lines, if the comment line has
                    222:   a q, starting with #q, the answer at the end of the run is quit. It
                    223:   permits to run test files in batch with ctest. The former workaround was
                    224:   $ echo q | imach foo.imach
                    225: 
1.195     brouard   226:   Revision 1.194  2015/08/18 13:32:00  brouard
                    227:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    228: 
1.194     brouard   229:   Revision 1.193  2015/08/04 07:17:42  brouard
                    230:   Summary: 0.98q4
                    231: 
1.193     brouard   232:   Revision 1.192  2015/07/16 16:49:02  brouard
                    233:   Summary: Fixing some outputs
                    234: 
1.192     brouard   235:   Revision 1.191  2015/07/14 10:00:33  brouard
                    236:   Summary: Some fixes
                    237: 
1.191     brouard   238:   Revision 1.190  2015/05/05 08:51:13  brouard
                    239:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    240: 
                    241:   Fix 1+age+.
                    242: 
1.190     brouard   243:   Revision 1.189  2015/04/30 14:45:16  brouard
                    244:   Summary: 0.98q2
                    245: 
1.189     brouard   246:   Revision 1.188  2015/04/30 08:27:53  brouard
                    247:   *** empty log message ***
                    248: 
1.188     brouard   249:   Revision 1.187  2015/04/29 09:11:15  brouard
                    250:   *** empty log message ***
                    251: 
1.187     brouard   252:   Revision 1.186  2015/04/23 12:01:52  brouard
                    253:   Summary: V1*age is working now, version 0.98q1
                    254: 
                    255:   Some codes had been disabled in order to simplify and Vn*age was
                    256:   working in the optimization phase, ie, giving correct MLE parameters,
                    257:   but, as usual, outputs were not correct and program core dumped.
                    258: 
1.186     brouard   259:   Revision 1.185  2015/03/11 13:26:42  brouard
                    260:   Summary: Inclusion of compile and links command line for Intel Compiler
                    261: 
1.185     brouard   262:   Revision 1.184  2015/03/11 11:52:39  brouard
                    263:   Summary: Back from Windows 8. Intel Compiler
                    264: 
1.184     brouard   265:   Revision 1.183  2015/03/10 20:34:32  brouard
                    266:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    267: 
                    268:   We use directest instead of original Powell test; probably no
                    269:   incidence on the results, but better justifications;
                    270:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    271:   wrong results.
                    272: 
1.183     brouard   273:   Revision 1.182  2015/02/12 08:19:57  brouard
                    274:   Summary: Trying to keep directest which seems simpler and more general
                    275:   Author: Nicolas Brouard
                    276: 
1.182     brouard   277:   Revision 1.181  2015/02/11 23:22:24  brouard
                    278:   Summary: Comments on Powell added
                    279: 
                    280:   Author:
                    281: 
1.181     brouard   282:   Revision 1.180  2015/02/11 17:33:45  brouard
                    283:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    284: 
1.180     brouard   285:   Revision 1.179  2015/01/04 09:57:06  brouard
                    286:   Summary: back to OS/X
                    287: 
1.179     brouard   288:   Revision 1.178  2015/01/04 09:35:48  brouard
                    289:   *** empty log message ***
                    290: 
1.178     brouard   291:   Revision 1.177  2015/01/03 18:40:56  brouard
                    292:   Summary: Still testing ilc32 on OSX
                    293: 
1.177     brouard   294:   Revision 1.176  2015/01/03 16:45:04  brouard
                    295:   *** empty log message ***
                    296: 
1.176     brouard   297:   Revision 1.175  2015/01/03 16:33:42  brouard
                    298:   *** empty log message ***
                    299: 
1.175     brouard   300:   Revision 1.174  2015/01/03 16:15:49  brouard
                    301:   Summary: Still in cross-compilation
                    302: 
1.174     brouard   303:   Revision 1.173  2015/01/03 12:06:26  brouard
                    304:   Summary: trying to detect cross-compilation
                    305: 
1.173     brouard   306:   Revision 1.172  2014/12/27 12:07:47  brouard
                    307:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    308: 
1.172     brouard   309:   Revision 1.171  2014/12/23 13:26:59  brouard
                    310:   Summary: Back from Visual C
                    311: 
                    312:   Still problem with utsname.h on Windows
                    313: 
1.171     brouard   314:   Revision 1.170  2014/12/23 11:17:12  brouard
                    315:   Summary: Cleaning some \%% back to %%
                    316: 
                    317:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    318: 
1.170     brouard   319:   Revision 1.169  2014/12/22 23:08:31  brouard
                    320:   Summary: 0.98p
                    321: 
                    322:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    323: 
1.169     brouard   324:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   325:   Summary: update
1.169     brouard   326: 
1.168     brouard   327:   Revision 1.167  2014/12/22 13:50:56  brouard
                    328:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    329: 
                    330:   Testing on Linux 64
                    331: 
1.167     brouard   332:   Revision 1.166  2014/12/22 11:40:47  brouard
                    333:   *** empty log message ***
                    334: 
1.166     brouard   335:   Revision 1.165  2014/12/16 11:20:36  brouard
                    336:   Summary: After compiling on Visual C
                    337: 
                    338:   * imach.c (Module): Merging 1.61 to 1.162
                    339: 
1.165     brouard   340:   Revision 1.164  2014/12/16 10:52:11  brouard
                    341:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    342: 
                    343:   * imach.c (Module): Merging 1.61 to 1.162
                    344: 
1.164     brouard   345:   Revision 1.163  2014/12/16 10:30:11  brouard
                    346:   * imach.c (Module): Merging 1.61 to 1.162
                    347: 
1.163     brouard   348:   Revision 1.162  2014/09/25 11:43:39  brouard
                    349:   Summary: temporary backup 0.99!
                    350: 
1.162     brouard   351:   Revision 1.1  2014/09/16 11:06:58  brouard
                    352:   Summary: With some code (wrong) for nlopt
                    353: 
                    354:   Author:
                    355: 
                    356:   Revision 1.161  2014/09/15 20:41:41  brouard
                    357:   Summary: Problem with macro SQR on Intel compiler
                    358: 
1.161     brouard   359:   Revision 1.160  2014/09/02 09:24:05  brouard
                    360:   *** empty log message ***
                    361: 
1.160     brouard   362:   Revision 1.159  2014/09/01 10:34:10  brouard
                    363:   Summary: WIN32
                    364:   Author: Brouard
                    365: 
1.159     brouard   366:   Revision 1.158  2014/08/27 17:11:51  brouard
                    367:   *** empty log message ***
                    368: 
1.158     brouard   369:   Revision 1.157  2014/08/27 16:26:55  brouard
                    370:   Summary: Preparing windows Visual studio version
                    371:   Author: Brouard
                    372: 
                    373:   In order to compile on Visual studio, time.h is now correct and time_t
                    374:   and tm struct should be used. difftime should be used but sometimes I
                    375:   just make the differences in raw time format (time(&now).
                    376:   Trying to suppress #ifdef LINUX
                    377:   Add xdg-open for __linux in order to open default browser.
                    378: 
1.157     brouard   379:   Revision 1.156  2014/08/25 20:10:10  brouard
                    380:   *** empty log message ***
                    381: 
1.156     brouard   382:   Revision 1.155  2014/08/25 18:32:34  brouard
                    383:   Summary: New compile, minor changes
                    384:   Author: Brouard
                    385: 
1.155     brouard   386:   Revision 1.154  2014/06/20 17:32:08  brouard
                    387:   Summary: Outputs now all graphs of convergence to period prevalence
                    388: 
1.154     brouard   389:   Revision 1.153  2014/06/20 16:45:46  brouard
                    390:   Summary: If 3 live state, convergence to period prevalence on same graph
                    391:   Author: Brouard
                    392: 
1.153     brouard   393:   Revision 1.152  2014/06/18 17:54:09  brouard
                    394:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    395: 
1.152     brouard   396:   Revision 1.151  2014/06/18 16:43:30  brouard
                    397:   *** empty log message ***
                    398: 
1.151     brouard   399:   Revision 1.150  2014/06/18 16:42:35  brouard
                    400:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    401:   Author: brouard
                    402: 
1.150     brouard   403:   Revision 1.149  2014/06/18 15:51:14  brouard
                    404:   Summary: Some fixes in parameter files errors
                    405:   Author: Nicolas Brouard
                    406: 
1.149     brouard   407:   Revision 1.148  2014/06/17 17:38:48  brouard
                    408:   Summary: Nothing new
                    409:   Author: Brouard
                    410: 
                    411:   Just a new packaging for OS/X version 0.98nS
                    412: 
1.148     brouard   413:   Revision 1.147  2014/06/16 10:33:11  brouard
                    414:   *** empty log message ***
                    415: 
1.147     brouard   416:   Revision 1.146  2014/06/16 10:20:28  brouard
                    417:   Summary: Merge
                    418:   Author: Brouard
                    419: 
                    420:   Merge, before building revised version.
                    421: 
1.146     brouard   422:   Revision 1.145  2014/06/10 21:23:15  brouard
                    423:   Summary: Debugging with valgrind
                    424:   Author: Nicolas Brouard
                    425: 
                    426:   Lot of changes in order to output the results with some covariates
                    427:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    428:   improve the code.
                    429:   No more memory valgrind error but a lot has to be done in order to
                    430:   continue the work of splitting the code into subroutines.
                    431:   Also, decodemodel has been improved. Tricode is still not
                    432:   optimal. nbcode should be improved. Documentation has been added in
                    433:   the source code.
                    434: 
1.144     brouard   435:   Revision 1.143  2014/01/26 09:45:38  brouard
                    436:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    437: 
                    438:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    439:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    440: 
1.143     brouard   441:   Revision 1.142  2014/01/26 03:57:36  brouard
                    442:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    443: 
                    444:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    445: 
1.142     brouard   446:   Revision 1.141  2014/01/26 02:42:01  brouard
                    447:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    448: 
1.141     brouard   449:   Revision 1.140  2011/09/02 10:37:54  brouard
                    450:   Summary: times.h is ok with mingw32 now.
                    451: 
1.140     brouard   452:   Revision 1.139  2010/06/14 07:50:17  brouard
                    453:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    454:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    455: 
1.139     brouard   456:   Revision 1.138  2010/04/30 18:19:40  brouard
                    457:   *** empty log message ***
                    458: 
1.138     brouard   459:   Revision 1.137  2010/04/29 18:11:38  brouard
                    460:   (Module): Checking covariates for more complex models
                    461:   than V1+V2. A lot of change to be done. Unstable.
                    462: 
1.137     brouard   463:   Revision 1.136  2010/04/26 20:30:53  brouard
                    464:   (Module): merging some libgsl code. Fixing computation
                    465:   of likelione (using inter/intrapolation if mle = 0) in order to
                    466:   get same likelihood as if mle=1.
                    467:   Some cleaning of code and comments added.
                    468: 
1.136     brouard   469:   Revision 1.135  2009/10/29 15:33:14  brouard
                    470:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    471: 
1.135     brouard   472:   Revision 1.134  2009/10/29 13:18:53  brouard
                    473:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    474: 
1.134     brouard   475:   Revision 1.133  2009/07/06 10:21:25  brouard
                    476:   just nforces
                    477: 
1.133     brouard   478:   Revision 1.132  2009/07/06 08:22:05  brouard
                    479:   Many tings
                    480: 
1.132     brouard   481:   Revision 1.131  2009/06/20 16:22:47  brouard
                    482:   Some dimensions resccaled
                    483: 
1.131     brouard   484:   Revision 1.130  2009/05/26 06:44:34  brouard
                    485:   (Module): Max Covariate is now set to 20 instead of 8. A
                    486:   lot of cleaning with variables initialized to 0. Trying to make
                    487:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    488: 
1.130     brouard   489:   Revision 1.129  2007/08/31 13:49:27  lievre
                    490:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    491: 
1.129     lievre    492:   Revision 1.128  2006/06/30 13:02:05  brouard
                    493:   (Module): Clarifications on computing e.j
                    494: 
1.128     brouard   495:   Revision 1.127  2006/04/28 18:11:50  brouard
                    496:   (Module): Yes the sum of survivors was wrong since
                    497:   imach-114 because nhstepm was no more computed in the age
                    498:   loop. Now we define nhstepma in the age loop.
                    499:   (Module): In order to speed up (in case of numerous covariates) we
                    500:   compute health expectancies (without variances) in a first step
                    501:   and then all the health expectancies with variances or standard
                    502:   deviation (needs data from the Hessian matrices) which slows the
                    503:   computation.
                    504:   In the future we should be able to stop the program is only health
                    505:   expectancies and graph are needed without standard deviations.
                    506: 
1.127     brouard   507:   Revision 1.126  2006/04/28 17:23:28  brouard
                    508:   (Module): Yes the sum of survivors was wrong since
                    509:   imach-114 because nhstepm was no more computed in the age
                    510:   loop. Now we define nhstepma in the age loop.
                    511:   Version 0.98h
                    512: 
1.126     brouard   513:   Revision 1.125  2006/04/04 15:20:31  lievre
                    514:   Errors in calculation of health expectancies. Age was not initialized.
                    515:   Forecasting file added.
                    516: 
                    517:   Revision 1.124  2006/03/22 17:13:53  lievre
                    518:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    519:   The log-likelihood is printed in the log file
                    520: 
                    521:   Revision 1.123  2006/03/20 10:52:43  brouard
                    522:   * imach.c (Module): <title> changed, corresponds to .htm file
                    523:   name. <head> headers where missing.
                    524: 
                    525:   * imach.c (Module): Weights can have a decimal point as for
                    526:   English (a comma might work with a correct LC_NUMERIC environment,
                    527:   otherwise the weight is truncated).
                    528:   Modification of warning when the covariates values are not 0 or
                    529:   1.
                    530:   Version 0.98g
                    531: 
                    532:   Revision 1.122  2006/03/20 09:45:41  brouard
                    533:   (Module): Weights can have a decimal point as for
                    534:   English (a comma might work with a correct LC_NUMERIC environment,
                    535:   otherwise the weight is truncated).
                    536:   Modification of warning when the covariates values are not 0 or
                    537:   1.
                    538:   Version 0.98g
                    539: 
                    540:   Revision 1.121  2006/03/16 17:45:01  lievre
                    541:   * imach.c (Module): Comments concerning covariates added
                    542: 
                    543:   * imach.c (Module): refinements in the computation of lli if
                    544:   status=-2 in order to have more reliable computation if stepm is
                    545:   not 1 month. Version 0.98f
                    546: 
                    547:   Revision 1.120  2006/03/16 15:10:38  lievre
                    548:   (Module): refinements in the computation of lli if
                    549:   status=-2 in order to have more reliable computation if stepm is
                    550:   not 1 month. Version 0.98f
                    551: 
                    552:   Revision 1.119  2006/03/15 17:42:26  brouard
                    553:   (Module): Bug if status = -2, the loglikelihood was
                    554:   computed as likelihood omitting the logarithm. Version O.98e
                    555: 
                    556:   Revision 1.118  2006/03/14 18:20:07  brouard
                    557:   (Module): varevsij Comments added explaining the second
                    558:   table of variances if popbased=1 .
                    559:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    560:   (Module): Function pstamp added
                    561:   (Module): Version 0.98d
                    562: 
                    563:   Revision 1.117  2006/03/14 17:16:22  brouard
                    564:   (Module): varevsij Comments added explaining the second
                    565:   table of variances if popbased=1 .
                    566:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    567:   (Module): Function pstamp added
                    568:   (Module): Version 0.98d
                    569: 
                    570:   Revision 1.116  2006/03/06 10:29:27  brouard
                    571:   (Module): Variance-covariance wrong links and
                    572:   varian-covariance of ej. is needed (Saito).
                    573: 
                    574:   Revision 1.115  2006/02/27 12:17:45  brouard
                    575:   (Module): One freematrix added in mlikeli! 0.98c
                    576: 
                    577:   Revision 1.114  2006/02/26 12:57:58  brouard
                    578:   (Module): Some improvements in processing parameter
                    579:   filename with strsep.
                    580: 
                    581:   Revision 1.113  2006/02/24 14:20:24  brouard
                    582:   (Module): Memory leaks checks with valgrind and:
                    583:   datafile was not closed, some imatrix were not freed and on matrix
                    584:   allocation too.
                    585: 
                    586:   Revision 1.112  2006/01/30 09:55:26  brouard
                    587:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    588: 
                    589:   Revision 1.111  2006/01/25 20:38:18  brouard
                    590:   (Module): Lots of cleaning and bugs added (Gompertz)
                    591:   (Module): Comments can be added in data file. Missing date values
                    592:   can be a simple dot '.'.
                    593: 
                    594:   Revision 1.110  2006/01/25 00:51:50  brouard
                    595:   (Module): Lots of cleaning and bugs added (Gompertz)
                    596: 
                    597:   Revision 1.109  2006/01/24 19:37:15  brouard
                    598:   (Module): Comments (lines starting with a #) are allowed in data.
                    599: 
                    600:   Revision 1.108  2006/01/19 18:05:42  lievre
                    601:   Gnuplot problem appeared...
                    602:   To be fixed
                    603: 
                    604:   Revision 1.107  2006/01/19 16:20:37  brouard
                    605:   Test existence of gnuplot in imach path
                    606: 
                    607:   Revision 1.106  2006/01/19 13:24:36  brouard
                    608:   Some cleaning and links added in html output
                    609: 
                    610:   Revision 1.105  2006/01/05 20:23:19  lievre
                    611:   *** empty log message ***
                    612: 
                    613:   Revision 1.104  2005/09/30 16:11:43  lievre
                    614:   (Module): sump fixed, loop imx fixed, and simplifications.
                    615:   (Module): If the status is missing at the last wave but we know
                    616:   that the person is alive, then we can code his/her status as -2
                    617:   (instead of missing=-1 in earlier versions) and his/her
                    618:   contributions to the likelihood is 1 - Prob of dying from last
                    619:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    620:   the healthy state at last known wave). Version is 0.98
                    621: 
                    622:   Revision 1.103  2005/09/30 15:54:49  lievre
                    623:   (Module): sump fixed, loop imx fixed, and simplifications.
                    624: 
                    625:   Revision 1.102  2004/09/15 17:31:30  brouard
                    626:   Add the possibility to read data file including tab characters.
                    627: 
                    628:   Revision 1.101  2004/09/15 10:38:38  brouard
                    629:   Fix on curr_time
                    630: 
                    631:   Revision 1.100  2004/07/12 18:29:06  brouard
                    632:   Add version for Mac OS X. Just define UNIX in Makefile
                    633: 
                    634:   Revision 1.99  2004/06/05 08:57:40  brouard
                    635:   *** empty log message ***
                    636: 
                    637:   Revision 1.98  2004/05/16 15:05:56  brouard
                    638:   New version 0.97 . First attempt to estimate force of mortality
                    639:   directly from the data i.e. without the need of knowing the health
                    640:   state at each age, but using a Gompertz model: log u =a + b*age .
                    641:   This is the basic analysis of mortality and should be done before any
                    642:   other analysis, in order to test if the mortality estimated from the
                    643:   cross-longitudinal survey is different from the mortality estimated
                    644:   from other sources like vital statistic data.
                    645: 
                    646:   The same imach parameter file can be used but the option for mle should be -3.
                    647: 
1.133     brouard   648:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   649:   former routines in order to include the new code within the former code.
                    650: 
                    651:   The output is very simple: only an estimate of the intercept and of
                    652:   the slope with 95% confident intervals.
                    653: 
                    654:   Current limitations:
                    655:   A) Even if you enter covariates, i.e. with the
                    656:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    657:   B) There is no computation of Life Expectancy nor Life Table.
                    658: 
                    659:   Revision 1.97  2004/02/20 13:25:42  lievre
                    660:   Version 0.96d. Population forecasting command line is (temporarily)
                    661:   suppressed.
                    662: 
                    663:   Revision 1.96  2003/07/15 15:38:55  brouard
                    664:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    665:   rewritten within the same printf. Workaround: many printfs.
                    666: 
                    667:   Revision 1.95  2003/07/08 07:54:34  brouard
                    668:   * imach.c (Repository):
                    669:   (Repository): Using imachwizard code to output a more meaningful covariance
                    670:   matrix (cov(a12,c31) instead of numbers.
                    671: 
                    672:   Revision 1.94  2003/06/27 13:00:02  brouard
                    673:   Just cleaning
                    674: 
                    675:   Revision 1.93  2003/06/25 16:33:55  brouard
                    676:   (Module): On windows (cygwin) function asctime_r doesn't
                    677:   exist so I changed back to asctime which exists.
                    678:   (Module): Version 0.96b
                    679: 
                    680:   Revision 1.92  2003/06/25 16:30:45  brouard
                    681:   (Module): On windows (cygwin) function asctime_r doesn't
                    682:   exist so I changed back to asctime which exists.
                    683: 
                    684:   Revision 1.91  2003/06/25 15:30:29  brouard
                    685:   * imach.c (Repository): Duplicated warning errors corrected.
                    686:   (Repository): Elapsed time after each iteration is now output. It
                    687:   helps to forecast when convergence will be reached. Elapsed time
                    688:   is stamped in powell.  We created a new html file for the graphs
                    689:   concerning matrix of covariance. It has extension -cov.htm.
                    690: 
                    691:   Revision 1.90  2003/06/24 12:34:15  brouard
                    692:   (Module): Some bugs corrected for windows. Also, when
                    693:   mle=-1 a template is output in file "or"mypar.txt with the design
                    694:   of the covariance matrix to be input.
                    695: 
                    696:   Revision 1.89  2003/06/24 12:30:52  brouard
                    697:   (Module): Some bugs corrected for windows. Also, when
                    698:   mle=-1 a template is output in file "or"mypar.txt with the design
                    699:   of the covariance matrix to be input.
                    700: 
                    701:   Revision 1.88  2003/06/23 17:54:56  brouard
                    702:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    703: 
                    704:   Revision 1.87  2003/06/18 12:26:01  brouard
                    705:   Version 0.96
                    706: 
                    707:   Revision 1.86  2003/06/17 20:04:08  brouard
                    708:   (Module): Change position of html and gnuplot routines and added
                    709:   routine fileappend.
                    710: 
                    711:   Revision 1.85  2003/06/17 13:12:43  brouard
                    712:   * imach.c (Repository): Check when date of death was earlier that
                    713:   current date of interview. It may happen when the death was just
                    714:   prior to the death. In this case, dh was negative and likelihood
                    715:   was wrong (infinity). We still send an "Error" but patch by
                    716:   assuming that the date of death was just one stepm after the
                    717:   interview.
                    718:   (Repository): Because some people have very long ID (first column)
                    719:   we changed int to long in num[] and we added a new lvector for
                    720:   memory allocation. But we also truncated to 8 characters (left
                    721:   truncation)
                    722:   (Repository): No more line truncation errors.
                    723: 
                    724:   Revision 1.84  2003/06/13 21:44:43  brouard
                    725:   * imach.c (Repository): Replace "freqsummary" at a correct
                    726:   place. It differs from routine "prevalence" which may be called
                    727:   many times. Probs is memory consuming and must be used with
                    728:   parcimony.
                    729:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    730: 
                    731:   Revision 1.83  2003/06/10 13:39:11  lievre
                    732:   *** empty log message ***
                    733: 
                    734:   Revision 1.82  2003/06/05 15:57:20  brouard
                    735:   Add log in  imach.c and  fullversion number is now printed.
                    736: 
                    737: */
                    738: /*
                    739:    Interpolated Markov Chain
                    740: 
                    741:   Short summary of the programme:
                    742:   
1.227     brouard   743:   This program computes Healthy Life Expectancies or State-specific
                    744:   (if states aren't health statuses) Expectancies from
                    745:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    746: 
                    747:   -1- a first survey ("cross") where individuals from different ages
                    748:   are interviewed on their health status or degree of disability (in
                    749:   the case of a health survey which is our main interest)
                    750: 
                    751:   -2- at least a second wave of interviews ("longitudinal") which
                    752:   measure each change (if any) in individual health status.  Health
                    753:   expectancies are computed from the time spent in each health state
                    754:   according to a model. More health states you consider, more time is
                    755:   necessary to reach the Maximum Likelihood of the parameters involved
                    756:   in the model.  The simplest model is the multinomial logistic model
                    757:   where pij is the probability to be observed in state j at the second
                    758:   wave conditional to be observed in state i at the first
                    759:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    760:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    761:   have a more complex model than "constant and age", you should modify
                    762:   the program where the markup *Covariates have to be included here
                    763:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   764:   convergence.
                    765: 
                    766:   The advantage of this computer programme, compared to a simple
                    767:   multinomial logistic model, is clear when the delay between waves is not
                    768:   identical for each individual. Also, if a individual missed an
                    769:   intermediate interview, the information is lost, but taken into
                    770:   account using an interpolation or extrapolation.  
                    771: 
                    772:   hPijx is the probability to be observed in state i at age x+h
                    773:   conditional to the observed state i at age x. The delay 'h' can be
                    774:   split into an exact number (nh*stepm) of unobserved intermediate
                    775:   states. This elementary transition (by month, quarter,
                    776:   semester or year) is modelled as a multinomial logistic.  The hPx
                    777:   matrix is simply the matrix product of nh*stepm elementary matrices
                    778:   and the contribution of each individual to the likelihood is simply
                    779:   hPijx.
                    780: 
                    781:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   782:   of the life expectancies. It also computes the period (stable) prevalence.
                    783: 
                    784: Back prevalence and projections:
1.227     brouard   785: 
                    786:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    787:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    788:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    789:    mobilavproj)
                    790: 
                    791:     Computes the back prevalence limit for any combination of
                    792:     covariate values k at any age between ageminpar and agemaxpar and
                    793:     returns it in **bprlim. In the loops,
                    794: 
                    795:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    796:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    797: 
                    798:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   799:    Computes for any combination of covariates k and any age between bage and fage 
                    800:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    801:                        oldm=oldms;savm=savms;
1.227     brouard   802: 
                    803:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   804:      Computes the transition matrix starting at age 'age' over
                    805:      'nhstepm*hstepm*stepm' months (i.e. until
                    806:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   807:      nhstepm*hstepm matrices. 
                    808: 
                    809:      Returns p3mat[i][j][h] after calling
                    810:      p3mat[i][j][h]=matprod2(newm,
                    811:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    812:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    813:      oldm);
1.226     brouard   814: 
                    815: Important routines
                    816: 
                    817: - func (or funcone), computes logit (pij) distinguishing
                    818:   o fixed variables (single or product dummies or quantitative);
                    819:   o varying variables by:
                    820:    (1) wave (single, product dummies, quantitative), 
                    821:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    822:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    823:        % varying dummy (not done) or quantitative (not done);
                    824: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    825:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    826: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    827:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    828:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   829: 
1.226     brouard   830: 
                    831:   
1.133     brouard   832:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    833:            Institut national d'études démographiques, Paris.
1.126     brouard   834:   This software have been partly granted by Euro-REVES, a concerted action
                    835:   from the European Union.
                    836:   It is copyrighted identically to a GNU software product, ie programme and
                    837:   software can be distributed freely for non commercial use. Latest version
                    838:   can be accessed at http://euroreves.ined.fr/imach .
                    839: 
                    840:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    841:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    842:   
                    843:   **********************************************************************/
                    844: /*
                    845:   main
                    846:   read parameterfile
                    847:   read datafile
                    848:   concatwav
                    849:   freqsummary
                    850:   if (mle >= 1)
                    851:     mlikeli
                    852:   print results files
                    853:   if mle==1 
                    854:      computes hessian
                    855:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    856:       begin-prev-date,...
                    857:   open gnuplot file
                    858:   open html file
1.145     brouard   859:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    860:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    861:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    862:     freexexit2 possible for memory heap.
                    863: 
                    864:   h Pij x                         | pij_nom  ficrestpij
                    865:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    866:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    867:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    868: 
                    869:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    870:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    871:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    872:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    873:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    874: 
1.126     brouard   875:   forecasting if prevfcast==1 prevforecast call prevalence()
                    876:   health expectancies
                    877:   Variance-covariance of DFLE
                    878:   prevalence()
                    879:    movingaverage()
                    880:   varevsij() 
                    881:   if popbased==1 varevsij(,popbased)
                    882:   total life expectancies
                    883:   Variance of period (stable) prevalence
                    884:  end
                    885: */
                    886: 
1.187     brouard   887: /* #define DEBUG */
                    888: /* #define DEBUGBRENT */
1.203     brouard   889: /* #define DEBUGLINMIN */
                    890: /* #define DEBUGHESS */
                    891: #define DEBUGHESSIJ
1.224     brouard   892: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   893: #define POWELL /* Instead of NLOPT */
1.224     brouard   894: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   895: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    896: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   897: 
                    898: #include <math.h>
                    899: #include <stdio.h>
                    900: #include <stdlib.h>
                    901: #include <string.h>
1.226     brouard   902: #include <ctype.h>
1.159     brouard   903: 
                    904: #ifdef _WIN32
                    905: #include <io.h>
1.172     brouard   906: #include <windows.h>
                    907: #include <tchar.h>
1.159     brouard   908: #else
1.126     brouard   909: #include <unistd.h>
1.159     brouard   910: #endif
1.126     brouard   911: 
                    912: #include <limits.h>
                    913: #include <sys/types.h>
1.171     brouard   914: 
                    915: #if defined(__GNUC__)
                    916: #include <sys/utsname.h> /* Doesn't work on Windows */
                    917: #endif
                    918: 
1.126     brouard   919: #include <sys/stat.h>
                    920: #include <errno.h>
1.159     brouard   921: /* extern int errno; */
1.126     brouard   922: 
1.157     brouard   923: /* #ifdef LINUX */
                    924: /* #include <time.h> */
                    925: /* #include "timeval.h" */
                    926: /* #else */
                    927: /* #include <sys/time.h> */
                    928: /* #endif */
                    929: 
1.126     brouard   930: #include <time.h>
                    931: 
1.136     brouard   932: #ifdef GSL
                    933: #include <gsl/gsl_errno.h>
                    934: #include <gsl/gsl_multimin.h>
                    935: #endif
                    936: 
1.167     brouard   937: 
1.162     brouard   938: #ifdef NLOPT
                    939: #include <nlopt.h>
                    940: typedef struct {
                    941:   double (* function)(double [] );
                    942: } myfunc_data ;
                    943: #endif
                    944: 
1.126     brouard   945: /* #include <libintl.h> */
                    946: /* #define _(String) gettext (String) */
                    947: 
1.251     brouard   948: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   949: 
                    950: #define GNUPLOTPROGRAM "gnuplot"
                    951: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    952: #define FILENAMELENGTH 132
                    953: 
                    954: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    955: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    956: 
1.144     brouard   957: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    958: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   959: 
                    960: #define NINTERVMAX 8
1.144     brouard   961: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    962: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    963: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   964: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   965: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    966: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   967: #define MAXN 20000
1.144     brouard   968: #define YEARM 12. /**< Number of months per year */
1.218     brouard   969: /* #define AGESUP 130 */
                    970: #define AGESUP 150
                    971: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   972: #define AGEBASE 40
1.194     brouard   973: #define AGEOVERFLOW 1.e20
1.164     brouard   974: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   975: #ifdef _WIN32
                    976: #define DIRSEPARATOR '\\'
                    977: #define CHARSEPARATOR "\\"
                    978: #define ODIRSEPARATOR '/'
                    979: #else
1.126     brouard   980: #define DIRSEPARATOR '/'
                    981: #define CHARSEPARATOR "/"
                    982: #define ODIRSEPARATOR '\\'
                    983: #endif
                    984: 
1.261   ! brouard   985: /* $Id: imach.c,v 1.260 2017/04/04 17:46:59 brouard Exp $ */
1.126     brouard   986: /* $State: Exp $ */
1.196     brouard   987: #include "version.h"
                    988: char version[]=__IMACH_VERSION__;
1.224     brouard   989: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.261   ! brouard   990: char fullversion[]="$Revision: 1.260 $ $Date: 2017/04/04 17:46:59 $"; 
1.126     brouard   991: char strstart[80];
                    992: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   993: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard   994: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard   995: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                    996: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                    997: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard   998: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                    999: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1000: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1001: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1002: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1003: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1004: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1005: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1006: int nsd=0; /**< Total number of single dummy variables (output) */
                   1007: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1008: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1009: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1010: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1011: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1012: int cptcov=0; /* Working variable */
1.218     brouard  1013: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1014: int npar=NPARMAX;
                   1015: int nlstate=2; /* Number of live states */
                   1016: int ndeath=1; /* Number of dead states */
1.130     brouard  1017: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1018: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1019: int popbased=0;
                   1020: 
                   1021: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1022: int maxwav=0; /* Maxim number of waves */
                   1023: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1024: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1025: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1026:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1027: int mle=1, weightopt=0;
1.126     brouard  1028: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1029: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1030: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1031:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1032: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1033: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1034: 
1.130     brouard  1035: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1036: double **matprod2(); /* test */
1.126     brouard  1037: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1038: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1039: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1040: 
1.136     brouard  1041: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1042: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1043: FILE *ficlog, *ficrespow;
1.130     brouard  1044: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1045: double fretone; /* Only one call to likelihood */
1.130     brouard  1046: long ipmx=0; /* Number of contributions */
1.126     brouard  1047: double sw; /* Sum of weights */
                   1048: char filerespow[FILENAMELENGTH];
                   1049: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1050: FILE *ficresilk;
                   1051: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1052: FILE *ficresprobmorprev;
                   1053: FILE *fichtm, *fichtmcov; /* Html File */
                   1054: FILE *ficreseij;
                   1055: char filerese[FILENAMELENGTH];
                   1056: FILE *ficresstdeij;
                   1057: char fileresstde[FILENAMELENGTH];
                   1058: FILE *ficrescveij;
                   1059: char filerescve[FILENAMELENGTH];
                   1060: FILE  *ficresvij;
                   1061: char fileresv[FILENAMELENGTH];
                   1062: FILE  *ficresvpl;
                   1063: char fileresvpl[FILENAMELENGTH];
                   1064: char title[MAXLINE];
1.234     brouard  1065: char model[MAXLINE]; /**< The model line */
1.217     brouard  1066: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1067: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1068: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1069: char command[FILENAMELENGTH];
                   1070: int  outcmd=0;
                   1071: 
1.217     brouard  1072: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1073: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1074: char filelog[FILENAMELENGTH]; /* Log file */
                   1075: char filerest[FILENAMELENGTH];
                   1076: char fileregp[FILENAMELENGTH];
                   1077: char popfile[FILENAMELENGTH];
                   1078: 
                   1079: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1080: 
1.157     brouard  1081: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1082: /* struct timezone tzp; */
                   1083: /* extern int gettimeofday(); */
                   1084: struct tm tml, *gmtime(), *localtime();
                   1085: 
                   1086: extern time_t time();
                   1087: 
                   1088: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1089: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1090: struct tm tm;
                   1091: 
1.126     brouard  1092: char strcurr[80], strfor[80];
                   1093: 
                   1094: char *endptr;
                   1095: long lval;
                   1096: double dval;
                   1097: 
                   1098: #define NR_END 1
                   1099: #define FREE_ARG char*
                   1100: #define FTOL 1.0e-10
                   1101: 
                   1102: #define NRANSI 
1.240     brouard  1103: #define ITMAX 200
                   1104: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1105: 
                   1106: #define TOL 2.0e-4 
                   1107: 
                   1108: #define CGOLD 0.3819660 
                   1109: #define ZEPS 1.0e-10 
                   1110: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1111: 
                   1112: #define GOLD 1.618034 
                   1113: #define GLIMIT 100.0 
                   1114: #define TINY 1.0e-20 
                   1115: 
                   1116: static double maxarg1,maxarg2;
                   1117: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1118: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1119:   
                   1120: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1121: #define rint(a) floor(a+0.5)
1.166     brouard  1122: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1123: #define mytinydouble 1.0e-16
1.166     brouard  1124: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1125: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1126: /* static double dsqrarg; */
                   1127: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1128: static double sqrarg;
                   1129: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1130: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1131: int agegomp= AGEGOMP;
                   1132: 
                   1133: int imx; 
                   1134: int stepm=1;
                   1135: /* Stepm, step in month: minimum step interpolation*/
                   1136: 
                   1137: int estepm;
                   1138: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1139: 
                   1140: int m,nb;
                   1141: long *num;
1.197     brouard  1142: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1143: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1144:                   covariate for which somebody answered excluding 
                   1145:                   undefined. Usually 2: 0 and 1. */
                   1146: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1147:                             covariate for which somebody answered including 
                   1148:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1149: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1150: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1151: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1152: double *ageexmed,*agecens;
                   1153: double dateintmean=0;
                   1154: 
                   1155: double *weight;
                   1156: int **s; /* Status */
1.141     brouard  1157: double *agedc;
1.145     brouard  1158: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1159:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1160:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1161: double **coqvar; /* Fixed quantitative covariate iqv */
                   1162: double ***cotvar; /* Time varying covariate itv */
                   1163: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1164: double  idx; 
                   1165: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1166: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1167: /*k          1  2   3   4     5    6    7     8    9 */
                   1168: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1169: /* Tndvar[k]    1   2   3               4          5 */
                   1170: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1171: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1172: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1173: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1174: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1175: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1176: /* Tprod[i]=k           4               7            */
                   1177: /* Tage[i]=k                  5               8      */
                   1178: /* */
                   1179: /* Type                    */
                   1180: /* V         1  2  3  4  5 */
                   1181: /*           F  F  V  V  V */
                   1182: /*           D  Q  D  D  Q */
                   1183: /*                         */
                   1184: int *TvarsD;
                   1185: int *TvarsDind;
                   1186: int *TvarsQ;
                   1187: int *TvarsQind;
                   1188: 
1.235     brouard  1189: #define MAXRESULTLINES 10
                   1190: int nresult=0;
1.258     brouard  1191: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1192: int TKresult[MAXRESULTLINES];
1.237     brouard  1193: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1194: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1195: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1196: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1197: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1198: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1199: 
1.234     brouard  1200: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1201: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1202: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1203: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1204: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1205: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1206: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1207: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1208: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1209: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1210: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1211: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1212: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1213: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1214: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1215: 
1.230     brouard  1216: int *Tvarsel; /**< Selected covariates for output */
                   1217: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1218: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1219: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1220: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1221: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1222: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1223: int *Tage;
1.227     brouard  1224: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1225: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1226: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1227: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1228: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1229: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1230: int **Tvard;
                   1231: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1232: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1233: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1234:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1235:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1236: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1237: double *lsurv, *lpop, *tpop;
                   1238: 
1.231     brouard  1239: #define FD 1; /* Fixed dummy covariate */
                   1240: #define FQ 2; /* Fixed quantitative covariate */
                   1241: #define FP 3; /* Fixed product covariate */
                   1242: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1243: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1244: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1245: #define VD 10; /* Varying dummy covariate */
                   1246: #define VQ 11; /* Varying quantitative covariate */
                   1247: #define VP 12; /* Varying product covariate */
                   1248: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1249: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1250: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1251: #define APFD 16; /* Age product * fixed dummy covariate */
                   1252: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1253: #define APVD 18; /* Age product * varying dummy covariate */
                   1254: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1255: 
                   1256: #define FTYPE 1; /* Fixed covariate */
                   1257: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1258: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1259: 
                   1260: struct kmodel{
                   1261:        int maintype; /* main type */
                   1262:        int subtype; /* subtype */
                   1263: };
                   1264: struct kmodel modell[NCOVMAX];
                   1265: 
1.143     brouard  1266: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1267: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1268: 
                   1269: /**************** split *************************/
                   1270: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1271: {
                   1272:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1273:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1274:   */ 
                   1275:   char *ss;                            /* pointer */
1.186     brouard  1276:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1277: 
                   1278:   l1 = strlen(path );                  /* length of path */
                   1279:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1280:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1281:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1282:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1283:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1284:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1285:     /* get current working directory */
                   1286:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1287: #ifdef WIN32
                   1288:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1289: #else
                   1290:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1291: #endif
1.126     brouard  1292:       return( GLOCK_ERROR_GETCWD );
                   1293:     }
                   1294:     /* got dirc from getcwd*/
                   1295:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1296:   } else {                             /* strip directory from path */
1.126     brouard  1297:     ss++;                              /* after this, the filename */
                   1298:     l2 = strlen( ss );                 /* length of filename */
                   1299:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1300:     strcpy( name, ss );                /* save file name */
                   1301:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1302:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1303:     printf(" DIRC2 = %s \n",dirc);
                   1304:   }
                   1305:   /* We add a separator at the end of dirc if not exists */
                   1306:   l1 = strlen( dirc );                 /* length of directory */
                   1307:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1308:     dirc[l1] =  DIRSEPARATOR;
                   1309:     dirc[l1+1] = 0; 
                   1310:     printf(" DIRC3 = %s \n",dirc);
                   1311:   }
                   1312:   ss = strrchr( name, '.' );           /* find last / */
                   1313:   if (ss >0){
                   1314:     ss++;
                   1315:     strcpy(ext,ss);                    /* save extension */
                   1316:     l1= strlen( name);
                   1317:     l2= strlen(ss)+1;
                   1318:     strncpy( finame, name, l1-l2);
                   1319:     finame[l1-l2]= 0;
                   1320:   }
                   1321: 
                   1322:   return( 0 );                         /* we're done */
                   1323: }
                   1324: 
                   1325: 
                   1326: /******************************************/
                   1327: 
                   1328: void replace_back_to_slash(char *s, char*t)
                   1329: {
                   1330:   int i;
                   1331:   int lg=0;
                   1332:   i=0;
                   1333:   lg=strlen(t);
                   1334:   for(i=0; i<= lg; i++) {
                   1335:     (s[i] = t[i]);
                   1336:     if (t[i]== '\\') s[i]='/';
                   1337:   }
                   1338: }
                   1339: 
1.132     brouard  1340: char *trimbb(char *out, char *in)
1.137     brouard  1341: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1342:   char *s;
                   1343:   s=out;
                   1344:   while (*in != '\0'){
1.137     brouard  1345:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1346:       in++;
                   1347:     }
                   1348:     *out++ = *in++;
                   1349:   }
                   1350:   *out='\0';
                   1351:   return s;
                   1352: }
                   1353: 
1.187     brouard  1354: /* char *substrchaine(char *out, char *in, char *chain) */
                   1355: /* { */
                   1356: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1357: /*   char *s, *t; */
                   1358: /*   t=in;s=out; */
                   1359: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1360: /*     *out++ = *in++; */
                   1361: /*   } */
                   1362: 
                   1363: /*   /\* *in matches *chain *\/ */
                   1364: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1365: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1366: /*   } */
                   1367: /*   in--; chain--; */
                   1368: /*   while ( (*in != '\0')){ */
                   1369: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1370: /*     *out++ = *in++; */
                   1371: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1372: /*   } */
                   1373: /*   *out='\0'; */
                   1374: /*   out=s; */
                   1375: /*   return out; */
                   1376: /* } */
                   1377: char *substrchaine(char *out, char *in, char *chain)
                   1378: {
                   1379:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1380:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1381: 
                   1382:   char *strloc;
                   1383: 
                   1384:   strcpy (out, in); 
                   1385:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1386:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1387:   if(strloc != NULL){ 
                   1388:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1389:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1390:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1391:   }
                   1392:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1393:   return out;
                   1394: }
                   1395: 
                   1396: 
1.145     brouard  1397: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1398: {
1.187     brouard  1399:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1400:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1401:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1402:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1403:   */
1.160     brouard  1404:   char *s, *t;
1.145     brouard  1405:   t=in;s=in;
                   1406:   while ((*in != occ) && (*in != '\0')){
                   1407:     *alocc++ = *in++;
                   1408:   }
                   1409:   if( *in == occ){
                   1410:     *(alocc)='\0';
                   1411:     s=++in;
                   1412:   }
                   1413:  
                   1414:   if (s == t) {/* occ not found */
                   1415:     *(alocc-(in-s))='\0';
                   1416:     in=s;
                   1417:   }
                   1418:   while ( *in != '\0'){
                   1419:     *blocc++ = *in++;
                   1420:   }
                   1421: 
                   1422:   *blocc='\0';
                   1423:   return t;
                   1424: }
1.137     brouard  1425: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1426: {
1.187     brouard  1427:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1428:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1429:      gives blocc="abcdef2ghi" and alocc="j".
                   1430:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1431:   */
                   1432:   char *s, *t;
                   1433:   t=in;s=in;
                   1434:   while (*in != '\0'){
                   1435:     while( *in == occ){
                   1436:       *blocc++ = *in++;
                   1437:       s=in;
                   1438:     }
                   1439:     *blocc++ = *in++;
                   1440:   }
                   1441:   if (s == t) /* occ not found */
                   1442:     *(blocc-(in-s))='\0';
                   1443:   else
                   1444:     *(blocc-(in-s)-1)='\0';
                   1445:   in=s;
                   1446:   while ( *in != '\0'){
                   1447:     *alocc++ = *in++;
                   1448:   }
                   1449: 
                   1450:   *alocc='\0';
                   1451:   return s;
                   1452: }
                   1453: 
1.126     brouard  1454: int nbocc(char *s, char occ)
                   1455: {
                   1456:   int i,j=0;
                   1457:   int lg=20;
                   1458:   i=0;
                   1459:   lg=strlen(s);
                   1460:   for(i=0; i<= lg; i++) {
1.234     brouard  1461:     if  (s[i] == occ ) j++;
1.126     brouard  1462:   }
                   1463:   return j;
                   1464: }
                   1465: 
1.137     brouard  1466: /* void cutv(char *u,char *v, char*t, char occ) */
                   1467: /* { */
                   1468: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1469: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1470: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1471: /*   int i,lg,j,p=0; */
                   1472: /*   i=0; */
                   1473: /*   lg=strlen(t); */
                   1474: /*   for(j=0; j<=lg-1; j++) { */
                   1475: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1476: /*   } */
1.126     brouard  1477: 
1.137     brouard  1478: /*   for(j=0; j<p; j++) { */
                   1479: /*     (u[j] = t[j]); */
                   1480: /*   } */
                   1481: /*      u[p]='\0'; */
1.126     brouard  1482: 
1.137     brouard  1483: /*    for(j=0; j<= lg; j++) { */
                   1484: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1485: /*   } */
                   1486: /* } */
1.126     brouard  1487: 
1.160     brouard  1488: #ifdef _WIN32
                   1489: char * strsep(char **pp, const char *delim)
                   1490: {
                   1491:   char *p, *q;
                   1492:          
                   1493:   if ((p = *pp) == NULL)
                   1494:     return 0;
                   1495:   if ((q = strpbrk (p, delim)) != NULL)
                   1496:   {
                   1497:     *pp = q + 1;
                   1498:     *q = '\0';
                   1499:   }
                   1500:   else
                   1501:     *pp = 0;
                   1502:   return p;
                   1503: }
                   1504: #endif
                   1505: 
1.126     brouard  1506: /********************** nrerror ********************/
                   1507: 
                   1508: void nrerror(char error_text[])
                   1509: {
                   1510:   fprintf(stderr,"ERREUR ...\n");
                   1511:   fprintf(stderr,"%s\n",error_text);
                   1512:   exit(EXIT_FAILURE);
                   1513: }
                   1514: /*********************** vector *******************/
                   1515: double *vector(int nl, int nh)
                   1516: {
                   1517:   double *v;
                   1518:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1519:   if (!v) nrerror("allocation failure in vector");
                   1520:   return v-nl+NR_END;
                   1521: }
                   1522: 
                   1523: /************************ free vector ******************/
                   1524: void free_vector(double*v, int nl, int nh)
                   1525: {
                   1526:   free((FREE_ARG)(v+nl-NR_END));
                   1527: }
                   1528: 
                   1529: /************************ivector *******************************/
                   1530: int *ivector(long nl,long nh)
                   1531: {
                   1532:   int *v;
                   1533:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1534:   if (!v) nrerror("allocation failure in ivector");
                   1535:   return v-nl+NR_END;
                   1536: }
                   1537: 
                   1538: /******************free ivector **************************/
                   1539: void free_ivector(int *v, long nl, long nh)
                   1540: {
                   1541:   free((FREE_ARG)(v+nl-NR_END));
                   1542: }
                   1543: 
                   1544: /************************lvector *******************************/
                   1545: long *lvector(long nl,long nh)
                   1546: {
                   1547:   long *v;
                   1548:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1549:   if (!v) nrerror("allocation failure in ivector");
                   1550:   return v-nl+NR_END;
                   1551: }
                   1552: 
                   1553: /******************free lvector **************************/
                   1554: void free_lvector(long *v, long nl, long nh)
                   1555: {
                   1556:   free((FREE_ARG)(v+nl-NR_END));
                   1557: }
                   1558: 
                   1559: /******************* imatrix *******************************/
                   1560: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1561:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1562: { 
                   1563:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1564:   int **m; 
                   1565:   
                   1566:   /* allocate pointers to rows */ 
                   1567:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1568:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1569:   m += NR_END; 
                   1570:   m -= nrl; 
                   1571:   
                   1572:   
                   1573:   /* allocate rows and set pointers to them */ 
                   1574:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1575:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1576:   m[nrl] += NR_END; 
                   1577:   m[nrl] -= ncl; 
                   1578:   
                   1579:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1580:   
                   1581:   /* return pointer to array of pointers to rows */ 
                   1582:   return m; 
                   1583: } 
                   1584: 
                   1585: /****************** free_imatrix *************************/
                   1586: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1587:       int **m;
                   1588:       long nch,ncl,nrh,nrl; 
                   1589:      /* free an int matrix allocated by imatrix() */ 
                   1590: { 
                   1591:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1592:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1593: } 
                   1594: 
                   1595: /******************* matrix *******************************/
                   1596: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1597: {
                   1598:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1599:   double **m;
                   1600: 
                   1601:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1602:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1603:   m += NR_END;
                   1604:   m -= nrl;
                   1605: 
                   1606:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1607:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1608:   m[nrl] += NR_END;
                   1609:   m[nrl] -= ncl;
                   1610: 
                   1611:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1612:   return m;
1.145     brouard  1613:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1614: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1615: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1616:    */
                   1617: }
                   1618: 
                   1619: /*************************free matrix ************************/
                   1620: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1621: {
                   1622:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1623:   free((FREE_ARG)(m+nrl-NR_END));
                   1624: }
                   1625: 
                   1626: /******************* ma3x *******************************/
                   1627: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1628: {
                   1629:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1630:   double ***m;
                   1631: 
                   1632:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1633:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1634:   m += NR_END;
                   1635:   m -= nrl;
                   1636: 
                   1637:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1638:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1639:   m[nrl] += NR_END;
                   1640:   m[nrl] -= ncl;
                   1641: 
                   1642:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1643: 
                   1644:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1645:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1646:   m[nrl][ncl] += NR_END;
                   1647:   m[nrl][ncl] -= nll;
                   1648:   for (j=ncl+1; j<=nch; j++) 
                   1649:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1650:   
                   1651:   for (i=nrl+1; i<=nrh; i++) {
                   1652:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1653:     for (j=ncl+1; j<=nch; j++) 
                   1654:       m[i][j]=m[i][j-1]+nlay;
                   1655:   }
                   1656:   return m; 
                   1657:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1658:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1659:   */
                   1660: }
                   1661: 
                   1662: /*************************free ma3x ************************/
                   1663: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1664: {
                   1665:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1666:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1667:   free((FREE_ARG)(m+nrl-NR_END));
                   1668: }
                   1669: 
                   1670: /*************** function subdirf ***********/
                   1671: char *subdirf(char fileres[])
                   1672: {
                   1673:   /* Caution optionfilefiname is hidden */
                   1674:   strcpy(tmpout,optionfilefiname);
                   1675:   strcat(tmpout,"/"); /* Add to the right */
                   1676:   strcat(tmpout,fileres);
                   1677:   return tmpout;
                   1678: }
                   1679: 
                   1680: /*************** function subdirf2 ***********/
                   1681: char *subdirf2(char fileres[], char *preop)
                   1682: {
                   1683:   
                   1684:   /* Caution optionfilefiname is hidden */
                   1685:   strcpy(tmpout,optionfilefiname);
                   1686:   strcat(tmpout,"/");
                   1687:   strcat(tmpout,preop);
                   1688:   strcat(tmpout,fileres);
                   1689:   return tmpout;
                   1690: }
                   1691: 
                   1692: /*************** function subdirf3 ***********/
                   1693: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1694: {
                   1695:   
                   1696:   /* Caution optionfilefiname is hidden */
                   1697:   strcpy(tmpout,optionfilefiname);
                   1698:   strcat(tmpout,"/");
                   1699:   strcat(tmpout,preop);
                   1700:   strcat(tmpout,preop2);
                   1701:   strcat(tmpout,fileres);
                   1702:   return tmpout;
                   1703: }
1.213     brouard  1704:  
                   1705: /*************** function subdirfext ***********/
                   1706: char *subdirfext(char fileres[], char *preop, char *postop)
                   1707: {
                   1708:   
                   1709:   strcpy(tmpout,preop);
                   1710:   strcat(tmpout,fileres);
                   1711:   strcat(tmpout,postop);
                   1712:   return tmpout;
                   1713: }
1.126     brouard  1714: 
1.213     brouard  1715: /*************** function subdirfext3 ***********/
                   1716: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1717: {
                   1718:   
                   1719:   /* Caution optionfilefiname is hidden */
                   1720:   strcpy(tmpout,optionfilefiname);
                   1721:   strcat(tmpout,"/");
                   1722:   strcat(tmpout,preop);
                   1723:   strcat(tmpout,fileres);
                   1724:   strcat(tmpout,postop);
                   1725:   return tmpout;
                   1726: }
                   1727:  
1.162     brouard  1728: char *asc_diff_time(long time_sec, char ascdiff[])
                   1729: {
                   1730:   long sec_left, days, hours, minutes;
                   1731:   days = (time_sec) / (60*60*24);
                   1732:   sec_left = (time_sec) % (60*60*24);
                   1733:   hours = (sec_left) / (60*60) ;
                   1734:   sec_left = (sec_left) %(60*60);
                   1735:   minutes = (sec_left) /60;
                   1736:   sec_left = (sec_left) % (60);
                   1737:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1738:   return ascdiff;
                   1739: }
                   1740: 
1.126     brouard  1741: /***************** f1dim *************************/
                   1742: extern int ncom; 
                   1743: extern double *pcom,*xicom;
                   1744: extern double (*nrfunc)(double []); 
                   1745:  
                   1746: double f1dim(double x) 
                   1747: { 
                   1748:   int j; 
                   1749:   double f;
                   1750:   double *xt; 
                   1751:  
                   1752:   xt=vector(1,ncom); 
                   1753:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1754:   f=(*nrfunc)(xt); 
                   1755:   free_vector(xt,1,ncom); 
                   1756:   return f; 
                   1757: } 
                   1758: 
                   1759: /*****************brent *************************/
                   1760: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1761: {
                   1762:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1763:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1764:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1765:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1766:    * returned function value. 
                   1767:   */
1.126     brouard  1768:   int iter; 
                   1769:   double a,b,d,etemp;
1.159     brouard  1770:   double fu=0,fv,fw,fx;
1.164     brouard  1771:   double ftemp=0.;
1.126     brouard  1772:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1773:   double e=0.0; 
                   1774:  
                   1775:   a=(ax < cx ? ax : cx); 
                   1776:   b=(ax > cx ? ax : cx); 
                   1777:   x=w=v=bx; 
                   1778:   fw=fv=fx=(*f)(x); 
                   1779:   for (iter=1;iter<=ITMAX;iter++) { 
                   1780:     xm=0.5*(a+b); 
                   1781:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1782:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1783:     printf(".");fflush(stdout);
                   1784:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1785: #ifdef DEBUGBRENT
1.126     brouard  1786:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1787:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1788:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1789: #endif
                   1790:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1791:       *xmin=x; 
                   1792:       return fx; 
                   1793:     } 
                   1794:     ftemp=fu;
                   1795:     if (fabs(e) > tol1) { 
                   1796:       r=(x-w)*(fx-fv); 
                   1797:       q=(x-v)*(fx-fw); 
                   1798:       p=(x-v)*q-(x-w)*r; 
                   1799:       q=2.0*(q-r); 
                   1800:       if (q > 0.0) p = -p; 
                   1801:       q=fabs(q); 
                   1802:       etemp=e; 
                   1803:       e=d; 
                   1804:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1805:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1806:       else { 
1.224     brouard  1807:                                d=p/q; 
                   1808:                                u=x+d; 
                   1809:                                if (u-a < tol2 || b-u < tol2) 
                   1810:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1811:       } 
                   1812:     } else { 
                   1813:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1814:     } 
                   1815:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1816:     fu=(*f)(u); 
                   1817:     if (fu <= fx) { 
                   1818:       if (u >= x) a=x; else b=x; 
                   1819:       SHFT(v,w,x,u) 
1.183     brouard  1820:       SHFT(fv,fw,fx,fu) 
                   1821:     } else { 
                   1822:       if (u < x) a=u; else b=u; 
                   1823:       if (fu <= fw || w == x) { 
1.224     brouard  1824:                                v=w; 
                   1825:                                w=u; 
                   1826:                                fv=fw; 
                   1827:                                fw=fu; 
1.183     brouard  1828:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1829:                                v=u; 
                   1830:                                fv=fu; 
1.183     brouard  1831:       } 
                   1832:     } 
1.126     brouard  1833:   } 
                   1834:   nrerror("Too many iterations in brent"); 
                   1835:   *xmin=x; 
                   1836:   return fx; 
                   1837: } 
                   1838: 
                   1839: /****************** mnbrak ***********************/
                   1840: 
                   1841: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1842:            double (*func)(double)) 
1.183     brouard  1843: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1844: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1845: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1846: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1847:    */
1.126     brouard  1848:   double ulim,u,r,q, dum;
                   1849:   double fu; 
1.187     brouard  1850: 
                   1851:   double scale=10.;
                   1852:   int iterscale=0;
                   1853: 
                   1854:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1855:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1856: 
                   1857: 
                   1858:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1859:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1860:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1861:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1862:   /* } */
                   1863: 
1.126     brouard  1864:   if (*fb > *fa) { 
                   1865:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1866:     SHFT(dum,*fb,*fa,dum) 
                   1867:   } 
1.126     brouard  1868:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1869:   *fc=(*func)(*cx); 
1.183     brouard  1870: #ifdef DEBUG
1.224     brouard  1871:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1872:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1873: #endif
1.224     brouard  1874:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1875:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1876:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1877:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1878:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1879:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1880:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1881:       fu=(*func)(u); 
1.163     brouard  1882: #ifdef DEBUG
                   1883:       /* f(x)=A(x-u)**2+f(u) */
                   1884:       double A, fparabu; 
                   1885:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1886:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1887:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1888:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1889:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1890:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1891:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1892:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1893: #endif 
1.184     brouard  1894: #ifdef MNBRAKORIGINAL
1.183     brouard  1895: #else
1.191     brouard  1896: /*       if (fu > *fc) { */
                   1897: /* #ifdef DEBUG */
                   1898: /*       printf("mnbrak4  fu > fc \n"); */
                   1899: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1900: /* #endif */
                   1901: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1902: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1903: /*     dum=u; /\* Shifting c and u *\/ */
                   1904: /*     u = *cx; */
                   1905: /*     *cx = dum; */
                   1906: /*     dum = fu; */
                   1907: /*     fu = *fc; */
                   1908: /*     *fc =dum; */
                   1909: /*       } else { /\* end *\/ */
                   1910: /* #ifdef DEBUG */
                   1911: /*       printf("mnbrak3  fu < fc \n"); */
                   1912: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1913: /* #endif */
                   1914: /*     dum=u; /\* Shifting c and u *\/ */
                   1915: /*     u = *cx; */
                   1916: /*     *cx = dum; */
                   1917: /*     dum = fu; */
                   1918: /*     fu = *fc; */
                   1919: /*     *fc =dum; */
                   1920: /*       } */
1.224     brouard  1921: #ifdef DEBUGMNBRAK
                   1922:                 double A, fparabu; 
                   1923:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1924:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1925:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1926:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1927: #endif
1.191     brouard  1928:       dum=u; /* Shifting c and u */
                   1929:       u = *cx;
                   1930:       *cx = dum;
                   1931:       dum = fu;
                   1932:       fu = *fc;
                   1933:       *fc =dum;
1.183     brouard  1934: #endif
1.162     brouard  1935:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1936: #ifdef DEBUG
1.224     brouard  1937:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1938:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1939: #endif
1.126     brouard  1940:       fu=(*func)(u); 
                   1941:       if (fu < *fc) { 
1.183     brouard  1942: #ifdef DEBUG
1.224     brouard  1943:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1944:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1945: #endif
                   1946:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1947:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1948: #ifdef DEBUG
                   1949:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1950: #endif
                   1951:       } 
1.162     brouard  1952:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1953: #ifdef DEBUG
1.224     brouard  1954:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1955:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1956: #endif
1.126     brouard  1957:       u=ulim; 
                   1958:       fu=(*func)(u); 
1.183     brouard  1959:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1960: #ifdef DEBUG
1.224     brouard  1961:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1962:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1963: #endif
1.126     brouard  1964:       u=(*cx)+GOLD*(*cx-*bx); 
                   1965:       fu=(*func)(u); 
1.224     brouard  1966: #ifdef DEBUG
                   1967:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1968:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1969: #endif
1.183     brouard  1970:     } /* end tests */
1.126     brouard  1971:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1972:     SHFT(*fa,*fb,*fc,fu) 
                   1973: #ifdef DEBUG
1.224     brouard  1974:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1975:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1976: #endif
                   1977:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1978: } 
                   1979: 
                   1980: /*************** linmin ************************/
1.162     brouard  1981: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1982: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1983: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1984: the value of func at the returned location p . This is actually all accomplished by calling the
                   1985: routines mnbrak and brent .*/
1.126     brouard  1986: int ncom; 
                   1987: double *pcom,*xicom;
                   1988: double (*nrfunc)(double []); 
                   1989:  
1.224     brouard  1990: #ifdef LINMINORIGINAL
1.126     brouard  1991: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1992: #else
                   1993: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   1994: #endif
1.126     brouard  1995: { 
                   1996:   double brent(double ax, double bx, double cx, 
                   1997:               double (*f)(double), double tol, double *xmin); 
                   1998:   double f1dim(double x); 
                   1999:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2000:              double *fc, double (*func)(double)); 
                   2001:   int j; 
                   2002:   double xx,xmin,bx,ax; 
                   2003:   double fx,fb,fa;
1.187     brouard  2004: 
1.203     brouard  2005: #ifdef LINMINORIGINAL
                   2006: #else
                   2007:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2008: #endif
                   2009:   
1.126     brouard  2010:   ncom=n; 
                   2011:   pcom=vector(1,n); 
                   2012:   xicom=vector(1,n); 
                   2013:   nrfunc=func; 
                   2014:   for (j=1;j<=n;j++) { 
                   2015:     pcom[j]=p[j]; 
1.202     brouard  2016:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2017:   } 
1.187     brouard  2018: 
1.203     brouard  2019: #ifdef LINMINORIGINAL
                   2020:   xx=1.;
                   2021: #else
                   2022:   axs=0.0;
                   2023:   xxs=1.;
                   2024:   do{
                   2025:     xx= xxs;
                   2026: #endif
1.187     brouard  2027:     ax=0.;
                   2028:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2029:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2030:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2031:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2032:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2033:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2034:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2035: #ifdef LINMINORIGINAL
                   2036: #else
                   2037:     if (fx != fx){
1.224     brouard  2038:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2039:                        printf("|");
                   2040:                        fprintf(ficlog,"|");
1.203     brouard  2041: #ifdef DEBUGLINMIN
1.224     brouard  2042:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2043: #endif
                   2044:     }
1.224     brouard  2045:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2046: #endif
                   2047:   
1.191     brouard  2048: #ifdef DEBUGLINMIN
                   2049:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2050:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2051: #endif
1.224     brouard  2052: #ifdef LINMINORIGINAL
                   2053: #else
                   2054:        if(fb == fx){ /* Flat function in the direction */
                   2055:                xmin=xx;
                   2056:     *flat=1;
                   2057:        }else{
                   2058:     *flat=0;
                   2059: #endif
                   2060:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2061:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2062:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2063:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2064:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2065:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2066: #ifdef DEBUG
1.224     brouard  2067:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2068:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2069: #endif
                   2070: #ifdef LINMINORIGINAL
                   2071: #else
                   2072:                        }
1.126     brouard  2073: #endif
1.191     brouard  2074: #ifdef DEBUGLINMIN
                   2075:   printf("linmin end ");
1.202     brouard  2076:   fprintf(ficlog,"linmin end ");
1.191     brouard  2077: #endif
1.126     brouard  2078:   for (j=1;j<=n;j++) { 
1.203     brouard  2079: #ifdef LINMINORIGINAL
                   2080:     xi[j] *= xmin; 
                   2081: #else
                   2082: #ifdef DEBUGLINMIN
                   2083:     if(xxs <1.0)
                   2084:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2085: #endif
                   2086:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2087: #ifdef DEBUGLINMIN
                   2088:     if(xxs <1.0)
                   2089:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2090: #endif
                   2091: #endif
1.187     brouard  2092:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2093:   } 
1.191     brouard  2094: #ifdef DEBUGLINMIN
1.203     brouard  2095:   printf("\n");
1.191     brouard  2096:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2097:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2098:   for (j=1;j<=n;j++) { 
1.202     brouard  2099:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2100:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2101:     if(j % ncovmodel == 0){
1.191     brouard  2102:       printf("\n");
1.202     brouard  2103:       fprintf(ficlog,"\n");
                   2104:     }
1.191     brouard  2105:   }
1.203     brouard  2106: #else
1.191     brouard  2107: #endif
1.126     brouard  2108:   free_vector(xicom,1,n); 
                   2109:   free_vector(pcom,1,n); 
                   2110: } 
                   2111: 
                   2112: 
                   2113: /*************** powell ************************/
1.162     brouard  2114: /*
                   2115: Minimization of a function func of n variables. Input consists of an initial starting point
                   2116: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2117: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2118: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2119: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2120: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2121:  */
1.224     brouard  2122: #ifdef LINMINORIGINAL
                   2123: #else
                   2124:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2125:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2126: #endif
1.126     brouard  2127: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2128:            double (*func)(double [])) 
                   2129: { 
1.224     brouard  2130: #ifdef LINMINORIGINAL
                   2131:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2132:              double (*func)(double [])); 
1.224     brouard  2133: #else 
1.241     brouard  2134:  void linmin(double p[], double xi[], int n, double *fret,
                   2135:             double (*func)(double []),int *flat); 
1.224     brouard  2136: #endif
1.239     brouard  2137:  int i,ibig,j,jk,k; 
1.126     brouard  2138:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2139:   double directest;
1.126     brouard  2140:   double fp,fptt;
                   2141:   double *xits;
                   2142:   int niterf, itmp;
1.224     brouard  2143: #ifdef LINMINORIGINAL
                   2144: #else
                   2145: 
                   2146:   flatdir=ivector(1,n); 
                   2147:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2148: #endif
1.126     brouard  2149: 
                   2150:   pt=vector(1,n); 
                   2151:   ptt=vector(1,n); 
                   2152:   xit=vector(1,n); 
                   2153:   xits=vector(1,n); 
                   2154:   *fret=(*func)(p); 
                   2155:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2156:   rcurr_time = time(NULL);  
1.126     brouard  2157:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2158:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2159:     ibig=0; 
                   2160:     del=0.0; 
1.157     brouard  2161:     rlast_time=rcurr_time;
                   2162:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2163:     rcurr_time = time(NULL);  
                   2164:     curr_time = *localtime(&rcurr_time);
                   2165:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2166:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2167: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2168:     for (i=1;i<=n;i++) {
1.126     brouard  2169:       fprintf(ficrespow," %.12lf", p[i]);
                   2170:     }
1.239     brouard  2171:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2172:     printf("\n#model=  1      +     age ");
                   2173:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2174:     if(nagesqr==1){
1.241     brouard  2175:        printf("  + age*age  ");
                   2176:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2177:     }
                   2178:     for(j=1;j <=ncovmodel-2;j++){
                   2179:       if(Typevar[j]==0) {
                   2180:        printf("  +      V%d  ",Tvar[j]);
                   2181:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2182:       }else if(Typevar[j]==1) {
                   2183:        printf("  +    V%d*age ",Tvar[j]);
                   2184:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2185:       }else if(Typevar[j]==2) {
                   2186:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2187:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2188:       }
                   2189:     }
1.126     brouard  2190:     printf("\n");
1.239     brouard  2191: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2192: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2193:     fprintf(ficlog,"\n");
1.239     brouard  2194:     for(i=1,jk=1; i <=nlstate; i++){
                   2195:       for(k=1; k <=(nlstate+ndeath); k++){
                   2196:        if (k != i) {
                   2197:          printf("%d%d ",i,k);
                   2198:          fprintf(ficlog,"%d%d ",i,k);
                   2199:          for(j=1; j <=ncovmodel; j++){
                   2200:            printf("%12.7f ",p[jk]);
                   2201:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2202:            jk++; 
                   2203:          }
                   2204:          printf("\n");
                   2205:          fprintf(ficlog,"\n");
                   2206:        }
                   2207:       }
                   2208:     }
1.241     brouard  2209:     if(*iter <=3 && *iter >1){
1.157     brouard  2210:       tml = *localtime(&rcurr_time);
                   2211:       strcpy(strcurr,asctime(&tml));
                   2212:       rforecast_time=rcurr_time; 
1.126     brouard  2213:       itmp = strlen(strcurr);
                   2214:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2215:        strcurr[itmp-1]='\0';
1.162     brouard  2216:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2217:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2218:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2219:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2220:        forecast_time = *localtime(&rforecast_time);
                   2221:        strcpy(strfor,asctime(&forecast_time));
                   2222:        itmp = strlen(strfor);
                   2223:        if(strfor[itmp-1]=='\n')
                   2224:          strfor[itmp-1]='\0';
                   2225:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2226:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2227:       }
                   2228:     }
1.187     brouard  2229:     for (i=1;i<=n;i++) { /* For each direction i */
                   2230:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2231:       fptt=(*fret); 
                   2232: #ifdef DEBUG
1.203     brouard  2233:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2234:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2235: #endif
1.203     brouard  2236:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2237:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2238: #ifdef LINMINORIGINAL
1.188     brouard  2239:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2240: #else
                   2241:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2242:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2243: #endif
                   2244:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2245:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2246:                                /* because that direction will be replaced unless the gain del is small */
                   2247:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2248:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2249:                                /* with the new direction. */
                   2250:                                del=fabs(fptt-(*fret)); 
                   2251:                                ibig=i; 
1.126     brouard  2252:       } 
                   2253: #ifdef DEBUG
                   2254:       printf("%d %.12e",i,(*fret));
                   2255:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2256:       for (j=1;j<=n;j++) {
1.224     brouard  2257:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2258:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2259:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2260:       }
                   2261:       for(j=1;j<=n;j++) {
1.225     brouard  2262:                                printf(" p(%d)=%.12e",j,p[j]);
                   2263:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2264:       }
                   2265:       printf("\n");
                   2266:       fprintf(ficlog,"\n");
                   2267: #endif
1.187     brouard  2268:     } /* end loop on each direction i */
                   2269:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2270:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2271:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2272:       for(j=1;j<=n;j++) {
1.225     brouard  2273:                                if(flatdir[j] >0){
                   2274:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2275:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2276:                                }
                   2277:                                /* printf("\n"); */
                   2278:                                /* fprintf(ficlog,"\n"); */
                   2279:                        }
1.243     brouard  2280:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2281:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2282:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2283:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2284:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2285:       /* decreased of more than 3.84  */
                   2286:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2287:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2288:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2289:                        
1.188     brouard  2290:       /* Starting the program with initial values given by a former maximization will simply change */
                   2291:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2292:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2293:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2294: #ifdef DEBUG
                   2295:       int k[2],l;
                   2296:       k[0]=1;
                   2297:       k[1]=-1;
                   2298:       printf("Max: %.12e",(*func)(p));
                   2299:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2300:       for (j=1;j<=n;j++) {
                   2301:        printf(" %.12e",p[j]);
                   2302:        fprintf(ficlog," %.12e",p[j]);
                   2303:       }
                   2304:       printf("\n");
                   2305:       fprintf(ficlog,"\n");
                   2306:       for(l=0;l<=1;l++) {
                   2307:        for (j=1;j<=n;j++) {
                   2308:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2309:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2310:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2311:        }
                   2312:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2313:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2314:       }
                   2315: #endif
                   2316: 
1.224     brouard  2317: #ifdef LINMINORIGINAL
                   2318: #else
                   2319:       free_ivector(flatdir,1,n); 
                   2320: #endif
1.126     brouard  2321:       free_vector(xit,1,n); 
                   2322:       free_vector(xits,1,n); 
                   2323:       free_vector(ptt,1,n); 
                   2324:       free_vector(pt,1,n); 
                   2325:       return; 
1.192     brouard  2326:     } /* enough precision */ 
1.240     brouard  2327:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2328:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2329:       ptt[j]=2.0*p[j]-pt[j]; 
                   2330:       xit[j]=p[j]-pt[j]; 
                   2331:       pt[j]=p[j]; 
                   2332:     } 
1.181     brouard  2333:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2334: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2335:                if (*iter <=4) {
1.225     brouard  2336: #else
                   2337: #endif
1.224     brouard  2338: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2339: #else
1.161     brouard  2340:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2341: #endif
1.162     brouard  2342:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2343:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2344:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2345:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2346:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2347:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2348:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2349:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2350:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2351:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2352:       /* mu² and del² are equal when f3=f1 */
                   2353:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2354:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2355:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2356:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2357: #ifdef NRCORIGINAL
                   2358:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2359: #else
                   2360:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2361:       t= t- del*SQR(fp-fptt);
1.183     brouard  2362: #endif
1.202     brouard  2363:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2364: #ifdef DEBUG
1.181     brouard  2365:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2366:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2367:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2368:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2369:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2370:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2371:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2372:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2373: #endif
1.183     brouard  2374: #ifdef POWELLORIGINAL
                   2375:       if (t < 0.0) { /* Then we use it for new direction */
                   2376: #else
1.182     brouard  2377:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2378:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2379:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2380:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2381:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2382:       } 
1.181     brouard  2383:       if (directest < 0.0) { /* Then we use it for new direction */
                   2384: #endif
1.191     brouard  2385: #ifdef DEBUGLINMIN
1.234     brouard  2386:        printf("Before linmin in direction P%d-P0\n",n);
                   2387:        for (j=1;j<=n;j++) {
                   2388:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2389:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2390:          if(j % ncovmodel == 0){
                   2391:            printf("\n");
                   2392:            fprintf(ficlog,"\n");
                   2393:          }
                   2394:        }
1.224     brouard  2395: #endif
                   2396: #ifdef LINMINORIGINAL
1.234     brouard  2397:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2398: #else
1.234     brouard  2399:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2400:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2401: #endif
1.234     brouard  2402:        
1.191     brouard  2403: #ifdef DEBUGLINMIN
1.234     brouard  2404:        for (j=1;j<=n;j++) { 
                   2405:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2406:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2407:          if(j % ncovmodel == 0){
                   2408:            printf("\n");
                   2409:            fprintf(ficlog,"\n");
                   2410:          }
                   2411:        }
1.224     brouard  2412: #endif
1.234     brouard  2413:        for (j=1;j<=n;j++) { 
                   2414:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2415:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2416:        }
1.224     brouard  2417: #ifdef LINMINORIGINAL
                   2418: #else
1.234     brouard  2419:        for (j=1, flatd=0;j<=n;j++) {
                   2420:          if(flatdir[j]>0)
                   2421:            flatd++;
                   2422:        }
                   2423:        if(flatd >0){
1.255     brouard  2424:          printf("%d flat directions: ",flatd);
                   2425:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2426:          for (j=1;j<=n;j++) { 
                   2427:            if(flatdir[j]>0){
                   2428:              printf("%d ",j);
                   2429:              fprintf(ficlog,"%d ",j);
                   2430:            }
                   2431:          }
                   2432:          printf("\n");
                   2433:          fprintf(ficlog,"\n");
                   2434:        }
1.191     brouard  2435: #endif
1.234     brouard  2436:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2437:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2438:        
1.126     brouard  2439: #ifdef DEBUG
1.234     brouard  2440:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2441:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2442:        for(j=1;j<=n;j++){
                   2443:          printf(" %lf",xit[j]);
                   2444:          fprintf(ficlog," %lf",xit[j]);
                   2445:        }
                   2446:        printf("\n");
                   2447:        fprintf(ficlog,"\n");
1.126     brouard  2448: #endif
1.192     brouard  2449:       } /* end of t or directest negative */
1.224     brouard  2450: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2451: #else
1.234     brouard  2452:       } /* end if (fptt < fp)  */
1.192     brouard  2453: #endif
1.225     brouard  2454: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2455:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2456: #else
1.224     brouard  2457: #endif
1.234     brouard  2458:                } /* loop iteration */ 
1.126     brouard  2459: } 
1.234     brouard  2460:   
1.126     brouard  2461: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2462:   
1.235     brouard  2463:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2464:   {
1.235     brouard  2465:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2466:        (and selected quantitative values in nres)
                   2467:        by left multiplying the unit
1.234     brouard  2468:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2469:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2470:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2471:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2472:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2473:   /* Initial matrix pimij */
                   2474:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2475:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2476:   /*  0,                   0                  , 1} */
                   2477:   /*
                   2478:    * and after some iteration: */
                   2479:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2480:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2481:   /*  0,                   0                  , 1} */
                   2482:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2483:   /* {0.51571254859325999, 0.4842874514067399, */
                   2484:   /*  0.51326036147820708, 0.48673963852179264} */
                   2485:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2486:     
1.126     brouard  2487:   int i, ii,j,k;
1.209     brouard  2488:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2489:   /* double **matprod2(); */ /* test */
1.218     brouard  2490:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2491:   double **newm;
1.209     brouard  2492:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2493:   int ncvloop=0;
1.169     brouard  2494:   
1.209     brouard  2495:   min=vector(1,nlstate);
                   2496:   max=vector(1,nlstate);
                   2497:   meandiff=vector(1,nlstate);
                   2498: 
1.218     brouard  2499:        /* Starting with matrix unity */
1.126     brouard  2500:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2501:     for (j=1;j<=nlstate+ndeath;j++){
                   2502:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2503:     }
1.169     brouard  2504:   
                   2505:   cov[1]=1.;
                   2506:   
                   2507:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2508:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2509:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2510:     ncvloop++;
1.126     brouard  2511:     newm=savm;
                   2512:     /* Covariates have to be included here again */
1.138     brouard  2513:     cov[2]=agefin;
1.187     brouard  2514:     if(nagesqr==1)
                   2515:       cov[3]= agefin*agefin;;
1.234     brouard  2516:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2517:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2518:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2519:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2520:     }
                   2521:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2522:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2523:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2524:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2525:     }
1.237     brouard  2526:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2527:       if(Dummy[Tvar[Tage[k]]]){
                   2528:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2529:       } else{
1.235     brouard  2530:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2531:       }
1.235     brouard  2532:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2533:     }
1.237     brouard  2534:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2535:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2536:       if(Dummy[Tvard[k][1]==0]){
                   2537:        if(Dummy[Tvard[k][2]==0]){
                   2538:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2539:        }else{
                   2540:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2541:        }
                   2542:       }else{
                   2543:        if(Dummy[Tvard[k][2]==0]){
                   2544:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2545:        }else{
                   2546:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2547:        }
                   2548:       }
1.234     brouard  2549:     }
1.138     brouard  2550:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2551:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2552:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2553:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2554:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2555:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2556:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2557:     
1.126     brouard  2558:     savm=oldm;
                   2559:     oldm=newm;
1.209     brouard  2560: 
                   2561:     for(j=1; j<=nlstate; j++){
                   2562:       max[j]=0.;
                   2563:       min[j]=1.;
                   2564:     }
                   2565:     for(i=1;i<=nlstate;i++){
                   2566:       sumnew=0;
                   2567:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2568:       for(j=1; j<=nlstate; j++){ 
                   2569:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2570:        max[j]=FMAX(max[j],prlim[i][j]);
                   2571:        min[j]=FMIN(min[j],prlim[i][j]);
                   2572:       }
                   2573:     }
                   2574: 
1.126     brouard  2575:     maxmax=0.;
1.209     brouard  2576:     for(j=1; j<=nlstate; j++){
                   2577:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2578:       maxmax=FMAX(maxmax,meandiff[j]);
                   2579:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2580:     } /* j loop */
1.203     brouard  2581:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2582:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2583:     if(maxmax < ftolpl){
1.209     brouard  2584:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2585:       free_vector(min,1,nlstate);
                   2586:       free_vector(max,1,nlstate);
                   2587:       free_vector(meandiff,1,nlstate);
1.126     brouard  2588:       return prlim;
                   2589:     }
1.169     brouard  2590:   } /* age loop */
1.208     brouard  2591:     /* After some age loop it doesn't converge */
1.209     brouard  2592:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2593: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2594:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2595:   free_vector(min,1,nlstate);
                   2596:   free_vector(max,1,nlstate);
                   2597:   free_vector(meandiff,1,nlstate);
1.208     brouard  2598:   
1.169     brouard  2599:   return prlim; /* should not reach here */
1.126     brouard  2600: }
                   2601: 
1.217     brouard  2602: 
                   2603:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2604: 
1.218     brouard  2605:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2606:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2607:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2608: {
1.218     brouard  2609:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2610:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2611:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2612:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2613:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2614:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2615:   /* Initial matrix pimij */
                   2616:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2617:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2618:   /*  0,                   0                  , 1} */
                   2619:   /*
                   2620:    * and after some iteration: */
                   2621:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2622:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2623:   /*  0,                   0                  , 1} */
                   2624:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2625:   /* {0.51571254859325999, 0.4842874514067399, */
                   2626:   /*  0.51326036147820708, 0.48673963852179264} */
                   2627:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2628: 
                   2629:   int i, ii,j,k;
1.247     brouard  2630:   int first=0;
1.217     brouard  2631:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2632:   /* double **matprod2(); */ /* test */
                   2633:   double **out, cov[NCOVMAX+1], **bmij();
                   2634:   double **newm;
1.218     brouard  2635:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2636:   double        **oldm, **savm;  /* for use */
                   2637: 
1.217     brouard  2638:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2639:   int ncvloop=0;
                   2640:   
                   2641:   min=vector(1,nlstate);
                   2642:   max=vector(1,nlstate);
                   2643:   meandiff=vector(1,nlstate);
                   2644: 
1.218     brouard  2645:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2646:        oldm=oldms; savm=savms;
                   2647: 
                   2648:        /* Starting with matrix unity */
                   2649:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2650:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2651:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2652:     }
                   2653:   
                   2654:   cov[1]=1.;
                   2655:   
                   2656:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2657:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2658:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2659:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2660:     ncvloop++;
1.218     brouard  2661:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2662:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2663:     /* Covariates have to be included here again */
                   2664:     cov[2]=agefin;
                   2665:     if(nagesqr==1)
                   2666:       cov[3]= agefin*agefin;;
1.242     brouard  2667:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2668:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2669:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2670:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2671:     }
                   2672:     /* for (k=1; k<=cptcovn;k++) { */
                   2673:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2674:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2675:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2676:     /* } */
                   2677:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2678:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2679:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2680:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2681:     }
                   2682:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2683:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2684:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2685:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2686:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2687:       if(Dummy[Tvar[Tage[k]]]){
                   2688:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2689:       } else{
                   2690:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2691:       }
                   2692:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2693:     }
                   2694:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2695:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2696:       if(Dummy[Tvard[k][1]==0]){
                   2697:        if(Dummy[Tvard[k][2]==0]){
                   2698:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2699:        }else{
                   2700:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2701:        }
                   2702:       }else{
                   2703:        if(Dummy[Tvard[k][2]==0]){
                   2704:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2705:        }else{
                   2706:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2707:        }
                   2708:       }
1.217     brouard  2709:     }
                   2710:     
                   2711:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2712:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2713:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2714:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2715:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2716:                /* ij should be linked to the correct index of cov */
                   2717:                /* age and covariate values ij are in 'cov', but we need to pass
                   2718:                 * ij for the observed prevalence at age and status and covariate
                   2719:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2720:                 */
                   2721:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2722:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2723:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2724:     savm=oldm;
                   2725:     oldm=newm;
                   2726:     for(j=1; j<=nlstate; j++){
                   2727:       max[j]=0.;
                   2728:       min[j]=1.;
                   2729:     }
                   2730:     for(j=1; j<=nlstate; j++){ 
                   2731:       for(i=1;i<=nlstate;i++){
1.234     brouard  2732:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2733:        bprlim[i][j]= newm[i][j];
                   2734:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2735:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2736:       }
                   2737:     }
1.218     brouard  2738:                
1.217     brouard  2739:     maxmax=0.;
                   2740:     for(i=1; i<=nlstate; i++){
                   2741:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2742:       maxmax=FMAX(maxmax,meandiff[i]);
                   2743:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2744:     } /* j loop */
                   2745:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2746:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2747:     if(maxmax < ftolpl){
1.220     brouard  2748:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2749:       free_vector(min,1,nlstate);
                   2750:       free_vector(max,1,nlstate);
                   2751:       free_vector(meandiff,1,nlstate);
                   2752:       return bprlim;
                   2753:     }
                   2754:   } /* age loop */
                   2755:     /* After some age loop it doesn't converge */
1.247     brouard  2756:   if(first){
                   2757:     first=1;
                   2758:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2759: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2760:   }
                   2761:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2762: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2763:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2764:   free_vector(min,1,nlstate);
                   2765:   free_vector(max,1,nlstate);
                   2766:   free_vector(meandiff,1,nlstate);
                   2767:   
                   2768:   return bprlim; /* should not reach here */
                   2769: }
                   2770: 
1.126     brouard  2771: /*************** transition probabilities ***************/ 
                   2772: 
                   2773: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2774: {
1.138     brouard  2775:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2776:      computes the probability to be observed in state j being in state i by appying the
                   2777:      model to the ncovmodel covariates (including constant and age).
                   2778:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2779:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2780:      ncth covariate in the global vector x is given by the formula:
                   2781:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2782:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2783:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2784:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2785:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2786:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2787:   */
                   2788:   double s1, lnpijopii;
1.126     brouard  2789:   /*double t34;*/
1.164     brouard  2790:   int i,j, nc, ii, jj;
1.126     brouard  2791: 
1.223     brouard  2792:   for(i=1; i<= nlstate; i++){
                   2793:     for(j=1; j<i;j++){
                   2794:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2795:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2796:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2797:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2798:       }
                   2799:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2800:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2801:     }
                   2802:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2803:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2804:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2805:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2806:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2807:       }
                   2808:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2809:     }
                   2810:   }
1.218     brouard  2811:   
1.223     brouard  2812:   for(i=1; i<= nlstate; i++){
                   2813:     s1=0;
                   2814:     for(j=1; j<i; j++){
                   2815:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2816:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2817:     }
                   2818:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2819:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2820:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2821:     }
                   2822:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2823:     ps[i][i]=1./(s1+1.);
                   2824:     /* Computing other pijs */
                   2825:     for(j=1; j<i; j++)
                   2826:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2827:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2828:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2829:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2830:   } /* end i */
1.218     brouard  2831:   
1.223     brouard  2832:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2833:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2834:       ps[ii][jj]=0;
                   2835:       ps[ii][ii]=1;
                   2836:     }
                   2837:   }
1.218     brouard  2838:   
                   2839:   
1.223     brouard  2840:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2841:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2842:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2843:   /*   } */
                   2844:   /*   printf("\n "); */
                   2845:   /* } */
                   2846:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2847:   /*
                   2848:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2849:                goto end;*/
1.223     brouard  2850:   return ps;
1.126     brouard  2851: }
                   2852: 
1.218     brouard  2853: /*************** backward transition probabilities ***************/ 
                   2854: 
                   2855:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2856: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2857:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2858: {
1.222     brouard  2859:   /* Computes the backward probability at age agefin and covariate ij
                   2860:    * and returns in **ps as well as **bmij.
                   2861:    */
1.218     brouard  2862:   int i, ii, j,k;
1.222     brouard  2863:   
                   2864:   double **out, **pmij();
                   2865:   double sumnew=0.;
1.218     brouard  2866:   double agefin;
1.222     brouard  2867:   
                   2868:   double **dnewm, **dsavm, **doldm;
                   2869:   double **bbmij;
                   2870:   
1.218     brouard  2871:   doldm=ddoldms; /* global pointers */
1.222     brouard  2872:   dnewm=ddnewms;
                   2873:   dsavm=ddsavms;
                   2874:   
                   2875:   agefin=cov[2];
                   2876:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2877:      the observed prevalence (with this covariate ij) */
                   2878:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2879:   /* We do have the matrix Px in savm  and we need pij */
                   2880:   for (j=1;j<=nlstate+ndeath;j++){
                   2881:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2882:     for (ii=1;ii<=nlstate;ii++){
                   2883:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2884:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2885:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2886:       if(sumnew >= 1.e-10){
                   2887:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2888:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2889:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2890:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2891:        /* }else */
                   2892:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2893:       }else{
1.242     brouard  2894:        ;
                   2895:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2896:       }
                   2897:     } /*End ii */
                   2898:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2899:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2900:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2901:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2902:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2903:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2904:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2905:   for (j=1;j<=nlstate+ndeath;j++){
                   2906:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2907:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2908:     }
                   2909:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2910:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2911:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2912:   /* end bmij */
                   2913:   return ps; 
1.218     brouard  2914: }
1.217     brouard  2915: /*************** transition probabilities ***************/ 
                   2916: 
1.218     brouard  2917: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2918: {
                   2919:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2920:      computes the probability to be observed in state j being in state i by appying the
                   2921:      model to the ncovmodel covariates (including constant and age).
                   2922:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2923:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2924:      ncth covariate in the global vector x is given by the formula:
                   2925:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2926:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2927:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2928:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2929:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2930:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2931:   */
                   2932:   double s1, lnpijopii;
                   2933:   /*double t34;*/
                   2934:   int i,j, nc, ii, jj;
                   2935: 
1.234     brouard  2936:   for(i=1; i<= nlstate; i++){
                   2937:     for(j=1; j<i;j++){
                   2938:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2939:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2940:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2941:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2942:       }
                   2943:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2944:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2945:     }
                   2946:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2947:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2948:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2949:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2950:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2951:       }
                   2952:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2953:     }
                   2954:   }
                   2955:   
                   2956:   for(i=1; i<= nlstate; i++){
                   2957:     s1=0;
                   2958:     for(j=1; j<i; j++){
                   2959:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2960:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2961:     }
                   2962:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2963:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2964:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2965:     }
                   2966:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2967:     ps[i][i]=1./(s1+1.);
                   2968:     /* Computing other pijs */
                   2969:     for(j=1; j<i; j++)
                   2970:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2971:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2972:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2973:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2974:   } /* end i */
                   2975:   
                   2976:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2977:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2978:       ps[ii][jj]=0;
                   2979:       ps[ii][ii]=1;
                   2980:     }
                   2981:   }
                   2982:   /* Added for backcast */ /* Transposed matrix too */
                   2983:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2984:     s1=0.;
                   2985:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2986:       s1+=ps[ii][jj];
                   2987:     }
                   2988:     for(ii=1; ii<= nlstate; ii++){
                   2989:       ps[ii][jj]=ps[ii][jj]/s1;
                   2990:     }
                   2991:   }
                   2992:   /* Transposition */
                   2993:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2994:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   2995:       s1=ps[ii][jj];
                   2996:       ps[ii][jj]=ps[jj][ii];
                   2997:       ps[jj][ii]=s1;
                   2998:     }
                   2999:   }
                   3000:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3001:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3002:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3003:   /*   } */
                   3004:   /*   printf("\n "); */
                   3005:   /* } */
                   3006:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3007:   /*
                   3008:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3009:     goto end;*/
                   3010:   return ps;
1.217     brouard  3011: }
                   3012: 
                   3013: 
1.126     brouard  3014: /**************** Product of 2 matrices ******************/
                   3015: 
1.145     brouard  3016: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3017: {
                   3018:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3019:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3020:   /* in, b, out are matrice of pointers which should have been initialized 
                   3021:      before: only the contents of out is modified. The function returns
                   3022:      a pointer to pointers identical to out */
1.145     brouard  3023:   int i, j, k;
1.126     brouard  3024:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3025:     for(k=ncolol; k<=ncoloh; k++){
                   3026:       out[i][k]=0.;
                   3027:       for(j=ncl; j<=nch; j++)
                   3028:        out[i][k] +=in[i][j]*b[j][k];
                   3029:     }
1.126     brouard  3030:   return out;
                   3031: }
                   3032: 
                   3033: 
                   3034: /************* Higher Matrix Product ***************/
                   3035: 
1.235     brouard  3036: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3037: {
1.218     brouard  3038:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3039:      'nhstepm*hstepm*stepm' months (i.e. until
                   3040:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3041:      nhstepm*hstepm matrices. 
                   3042:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3043:      (typically every 2 years instead of every month which is too big 
                   3044:      for the memory).
                   3045:      Model is determined by parameters x and covariates have to be 
                   3046:      included manually here. 
                   3047: 
                   3048:      */
                   3049: 
                   3050:   int i, j, d, h, k;
1.131     brouard  3051:   double **out, cov[NCOVMAX+1];
1.126     brouard  3052:   double **newm;
1.187     brouard  3053:   double agexact;
1.214     brouard  3054:   double agebegin, ageend;
1.126     brouard  3055: 
                   3056:   /* Hstepm could be zero and should return the unit matrix */
                   3057:   for (i=1;i<=nlstate+ndeath;i++)
                   3058:     for (j=1;j<=nlstate+ndeath;j++){
                   3059:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3060:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3061:     }
                   3062:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3063:   for(h=1; h <=nhstepm; h++){
                   3064:     for(d=1; d <=hstepm; d++){
                   3065:       newm=savm;
                   3066:       /* Covariates have to be included here again */
                   3067:       cov[1]=1.;
1.214     brouard  3068:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3069:       cov[2]=agexact;
                   3070:       if(nagesqr==1)
1.227     brouard  3071:        cov[3]= agexact*agexact;
1.235     brouard  3072:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3073:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3074:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3075:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3076:       }
                   3077:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3078:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3079:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3080:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3081:       }
                   3082:       for (k=1; k<=cptcovage;k++){
                   3083:        if(Dummy[Tvar[Tage[k]]]){
                   3084:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3085:        } else{
                   3086:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3087:        }
                   3088:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3089:       }
                   3090:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3091:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3092:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3093:       }
                   3094:       /* for (k=1; k<=cptcovn;k++)  */
                   3095:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3096:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3097:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3098:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3099:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3100:       
                   3101:       
1.126     brouard  3102:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3103:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3104:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3105:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3106:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3107:       /* if((int)age == 70){ */
                   3108:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3109:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3110:       /*         printf("%d pmmij ",i); */
                   3111:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3112:       /*           printf("%f ",pmmij[i][j]); */
                   3113:       /*         } */
                   3114:       /*         printf(" oldm "); */
                   3115:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3116:       /*           printf("%f ",oldm[i][j]); */
                   3117:       /*         } */
                   3118:       /*         printf("\n"); */
                   3119:       /*       } */
                   3120:       /* } */
1.126     brouard  3121:       savm=oldm;
                   3122:       oldm=newm;
                   3123:     }
                   3124:     for(i=1; i<=nlstate+ndeath; i++)
                   3125:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3126:                                po[i][j][h]=newm[i][j];
                   3127:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3128:       }
1.128     brouard  3129:     /*printf("h=%d ",h);*/
1.126     brouard  3130:   } /* end h */
1.218     brouard  3131:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3132:   return po;
                   3133: }
                   3134: 
1.217     brouard  3135: /************* Higher Back Matrix Product ***************/
1.218     brouard  3136: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3137: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3138: {
1.218     brouard  3139:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3140:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3141:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3142:      nhstepm*hstepm matrices.
                   3143:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3144:      (typically every 2 years instead of every month which is too big
1.217     brouard  3145:      for the memory).
1.218     brouard  3146:      Model is determined by parameters x and covariates have to be
                   3147:      included manually here.
1.217     brouard  3148: 
1.222     brouard  3149:   */
1.217     brouard  3150: 
                   3151:   int i, j, d, h, k;
                   3152:   double **out, cov[NCOVMAX+1];
                   3153:   double **newm;
                   3154:   double agexact;
                   3155:   double agebegin, ageend;
1.222     brouard  3156:   double **oldm, **savm;
1.217     brouard  3157: 
1.222     brouard  3158:   oldm=oldms;savm=savms;
1.217     brouard  3159:   /* Hstepm could be zero and should return the unit matrix */
                   3160:   for (i=1;i<=nlstate+ndeath;i++)
                   3161:     for (j=1;j<=nlstate+ndeath;j++){
                   3162:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3163:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3164:     }
                   3165:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3166:   for(h=1; h <=nhstepm; h++){
                   3167:     for(d=1; d <=hstepm; d++){
                   3168:       newm=savm;
                   3169:       /* Covariates have to be included here again */
                   3170:       cov[1]=1.;
                   3171:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3172:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3173:       cov[2]=agexact;
                   3174:       if(nagesqr==1)
1.222     brouard  3175:        cov[3]= agexact*agexact;
1.218     brouard  3176:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3177:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3178:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3179:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3180:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3181:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3182:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3183:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3184:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3185:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3186:                        
                   3187:                        
1.217     brouard  3188:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3189:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3190:       /* Careful transposed matrix */
1.222     brouard  3191:       /* age is in cov[2] */
1.218     brouard  3192:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3193:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3194:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3195:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3196:       /* if((int)age == 70){ */
                   3197:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3198:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3199:       /*         printf("%d pmmij ",i); */
                   3200:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3201:       /*           printf("%f ",pmmij[i][j]); */
                   3202:       /*         } */
                   3203:       /*         printf(" oldm "); */
                   3204:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3205:       /*           printf("%f ",oldm[i][j]); */
                   3206:       /*         } */
                   3207:       /*         printf("\n"); */
                   3208:       /*       } */
                   3209:       /* } */
                   3210:       savm=oldm;
                   3211:       oldm=newm;
                   3212:     }
                   3213:     for(i=1; i<=nlstate+ndeath; i++)
                   3214:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3215:        po[i][j][h]=newm[i][j];
                   3216:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3217:       }
                   3218:     /*printf("h=%d ",h);*/
                   3219:   } /* end h */
1.222     brouard  3220:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3221:   return po;
                   3222: }
                   3223: 
                   3224: 
1.162     brouard  3225: #ifdef NLOPT
                   3226:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3227:   double fret;
                   3228:   double *xt;
                   3229:   int j;
                   3230:   myfunc_data *d2 = (myfunc_data *) pd;
                   3231: /* xt = (p1-1); */
                   3232:   xt=vector(1,n); 
                   3233:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3234: 
                   3235:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3236:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3237:   printf("Function = %.12lf ",fret);
                   3238:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3239:   printf("\n");
                   3240:  free_vector(xt,1,n);
                   3241:   return fret;
                   3242: }
                   3243: #endif
1.126     brouard  3244: 
                   3245: /*************** log-likelihood *************/
                   3246: double func( double *x)
                   3247: {
1.226     brouard  3248:   int i, ii, j, k, mi, d, kk;
                   3249:   int ioffset=0;
                   3250:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3251:   double **out;
                   3252:   double lli; /* Individual log likelihood */
                   3253:   int s1, s2;
1.228     brouard  3254:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3255:   double bbh, survp;
                   3256:   long ipmx;
                   3257:   double agexact;
                   3258:   /*extern weight */
                   3259:   /* We are differentiating ll according to initial status */
                   3260:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3261:   /*for(i=1;i<imx;i++) 
                   3262:     printf(" %d\n",s[4][i]);
                   3263:   */
1.162     brouard  3264: 
1.226     brouard  3265:   ++countcallfunc;
1.162     brouard  3266: 
1.226     brouard  3267:   cov[1]=1.;
1.126     brouard  3268: 
1.226     brouard  3269:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3270:   ioffset=0;
1.226     brouard  3271:   if(mle==1){
                   3272:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3273:       /* Computes the values of the ncovmodel covariates of the model
                   3274:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3275:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3276:         to be observed in j being in i according to the model.
                   3277:       */
1.243     brouard  3278:       ioffset=2+nagesqr ;
1.233     brouard  3279:    /* Fixed */
1.234     brouard  3280:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3281:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3282:       }
1.226     brouard  3283:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3284:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3285:         has been calculated etc */
                   3286:       /* For an individual i, wav[i] gives the number of effective waves */
                   3287:       /* We compute the contribution to Likelihood of each effective transition
                   3288:         mw[mi][i] is real wave of the mi th effectve wave */
                   3289:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3290:         s2=s[mw[mi+1][i]][i];
                   3291:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3292:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3293:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3294:       */
                   3295:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3296:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3297:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3298:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3299:        }
                   3300:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3301:          for (j=1;j<=nlstate+ndeath;j++){
                   3302:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3303:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3304:          }
                   3305:        for(d=0; d<dh[mi][i]; d++){
                   3306:          newm=savm;
                   3307:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3308:          cov[2]=agexact;
                   3309:          if(nagesqr==1)
                   3310:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3311:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3312:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3313:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3314:          else
                   3315:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3316:          }
                   3317:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3318:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3319:          savm=oldm;
                   3320:          oldm=newm;
                   3321:        } /* end mult */
                   3322:        
                   3323:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3324:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3325:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3326:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3327:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3328:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3329:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3330:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3331:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3332:                                 * -stepm/2 to stepm/2 .
                   3333:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3334:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3335:                                 */
1.234     brouard  3336:        s1=s[mw[mi][i]][i];
                   3337:        s2=s[mw[mi+1][i]][i];
                   3338:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3339:        /* bias bh is positive if real duration
                   3340:         * is higher than the multiple of stepm and negative otherwise.
                   3341:         */
                   3342:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3343:        if( s2 > nlstate){ 
                   3344:          /* i.e. if s2 is a death state and if the date of death is known 
                   3345:             then the contribution to the likelihood is the probability to 
                   3346:             die between last step unit time and current  step unit time, 
                   3347:             which is also equal to probability to die before dh 
                   3348:             minus probability to die before dh-stepm . 
                   3349:             In version up to 0.92 likelihood was computed
                   3350:             as if date of death was unknown. Death was treated as any other
                   3351:             health state: the date of the interview describes the actual state
                   3352:             and not the date of a change in health state. The former idea was
                   3353:             to consider that at each interview the state was recorded
                   3354:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3355:             introduced the exact date of death then we should have modified
                   3356:             the contribution of an exact death to the likelihood. This new
                   3357:             contribution is smaller and very dependent of the step unit
                   3358:             stepm. It is no more the probability to die between last interview
                   3359:             and month of death but the probability to survive from last
                   3360:             interview up to one month before death multiplied by the
                   3361:             probability to die within a month. Thanks to Chris
                   3362:             Jackson for correcting this bug.  Former versions increased
                   3363:             mortality artificially. The bad side is that we add another loop
                   3364:             which slows down the processing. The difference can be up to 10%
                   3365:             lower mortality.
                   3366:          */
                   3367:          /* If, at the beginning of the maximization mostly, the
                   3368:             cumulative probability or probability to be dead is
                   3369:             constant (ie = 1) over time d, the difference is equal to
                   3370:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3371:             s1 at precedent wave, to be dead a month before current
                   3372:             wave is equal to probability, being at state s1 at
                   3373:             precedent wave, to be dead at mont of the current
                   3374:             wave. Then the observed probability (that this person died)
                   3375:             is null according to current estimated parameter. In fact,
                   3376:             it should be very low but not zero otherwise the log go to
                   3377:             infinity.
                   3378:          */
1.183     brouard  3379: /* #ifdef INFINITYORIGINAL */
                   3380: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3381: /* #else */
                   3382: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3383: /*         lli=log(mytinydouble); */
                   3384: /*       else */
                   3385: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3386: /* #endif */
1.226     brouard  3387:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3388:          
1.226     brouard  3389:        } else if  ( s2==-1 ) { /* alive */
                   3390:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3391:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3392:          /*survp += out[s1][j]; */
                   3393:          lli= log(survp);
                   3394:        }
                   3395:        else if  (s2==-4) { 
                   3396:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3397:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3398:          lli= log(survp); 
                   3399:        } 
                   3400:        else if  (s2==-5) { 
                   3401:          for (j=1,survp=0. ; j<=2; j++)  
                   3402:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3403:          lli= log(survp); 
                   3404:        } 
                   3405:        else{
                   3406:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3407:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3408:        } 
                   3409:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3410:        /*if(lli ==000.0)*/
                   3411:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3412:        ipmx +=1;
                   3413:        sw += weight[i];
                   3414:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3415:        /* if (lli < log(mytinydouble)){ */
                   3416:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3417:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3418:        /* } */
                   3419:       } /* end of wave */
                   3420:     } /* end of individual */
                   3421:   }  else if(mle==2){
                   3422:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3423:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3424:       for(mi=1; mi<= wav[i]-1; mi++){
                   3425:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3426:          for (j=1;j<=nlstate+ndeath;j++){
                   3427:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3428:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3429:          }
                   3430:        for(d=0; d<=dh[mi][i]; d++){
                   3431:          newm=savm;
                   3432:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3433:          cov[2]=agexact;
                   3434:          if(nagesqr==1)
                   3435:            cov[3]= agexact*agexact;
                   3436:          for (kk=1; kk<=cptcovage;kk++) {
                   3437:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3438:          }
                   3439:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3440:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3441:          savm=oldm;
                   3442:          oldm=newm;
                   3443:        } /* end mult */
                   3444:       
                   3445:        s1=s[mw[mi][i]][i];
                   3446:        s2=s[mw[mi+1][i]][i];
                   3447:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3448:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3449:        ipmx +=1;
                   3450:        sw += weight[i];
                   3451:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3452:       } /* end of wave */
                   3453:     } /* end of individual */
                   3454:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3455:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3456:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3457:       for(mi=1; mi<= wav[i]-1; mi++){
                   3458:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3459:          for (j=1;j<=nlstate+ndeath;j++){
                   3460:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3461:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3462:          }
                   3463:        for(d=0; d<dh[mi][i]; d++){
                   3464:          newm=savm;
                   3465:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3466:          cov[2]=agexact;
                   3467:          if(nagesqr==1)
                   3468:            cov[3]= agexact*agexact;
                   3469:          for (kk=1; kk<=cptcovage;kk++) {
                   3470:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3471:          }
                   3472:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3473:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3474:          savm=oldm;
                   3475:          oldm=newm;
                   3476:        } /* end mult */
                   3477:       
                   3478:        s1=s[mw[mi][i]][i];
                   3479:        s2=s[mw[mi+1][i]][i];
                   3480:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3481:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3482:        ipmx +=1;
                   3483:        sw += weight[i];
                   3484:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3485:       } /* end of wave */
                   3486:     } /* end of individual */
                   3487:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3488:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3489:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3490:       for(mi=1; mi<= wav[i]-1; mi++){
                   3491:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3492:          for (j=1;j<=nlstate+ndeath;j++){
                   3493:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3494:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3495:          }
                   3496:        for(d=0; d<dh[mi][i]; d++){
                   3497:          newm=savm;
                   3498:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3499:          cov[2]=agexact;
                   3500:          if(nagesqr==1)
                   3501:            cov[3]= agexact*agexact;
                   3502:          for (kk=1; kk<=cptcovage;kk++) {
                   3503:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3504:          }
1.126     brouard  3505:        
1.226     brouard  3506:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3507:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3508:          savm=oldm;
                   3509:          oldm=newm;
                   3510:        } /* end mult */
                   3511:       
                   3512:        s1=s[mw[mi][i]][i];
                   3513:        s2=s[mw[mi+1][i]][i];
                   3514:        if( s2 > nlstate){ 
                   3515:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3516:        } else if  ( s2==-1 ) { /* alive */
                   3517:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3518:            survp += out[s1][j];
                   3519:          lli= log(survp);
                   3520:        }else{
                   3521:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3522:        }
                   3523:        ipmx +=1;
                   3524:        sw += weight[i];
                   3525:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3526: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3527:       } /* end of wave */
                   3528:     } /* end of individual */
                   3529:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3530:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3531:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3532:       for(mi=1; mi<= wav[i]-1; mi++){
                   3533:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3534:          for (j=1;j<=nlstate+ndeath;j++){
                   3535:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3536:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3537:          }
                   3538:        for(d=0; d<dh[mi][i]; d++){
                   3539:          newm=savm;
                   3540:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3541:          cov[2]=agexact;
                   3542:          if(nagesqr==1)
                   3543:            cov[3]= agexact*agexact;
                   3544:          for (kk=1; kk<=cptcovage;kk++) {
                   3545:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3546:          }
1.126     brouard  3547:        
1.226     brouard  3548:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3549:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3550:          savm=oldm;
                   3551:          oldm=newm;
                   3552:        } /* end mult */
                   3553:       
                   3554:        s1=s[mw[mi][i]][i];
                   3555:        s2=s[mw[mi+1][i]][i];
                   3556:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3557:        ipmx +=1;
                   3558:        sw += weight[i];
                   3559:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3560:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3561:       } /* end of wave */
                   3562:     } /* end of individual */
                   3563:   } /* End of if */
                   3564:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3565:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3566:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3567:   return -l;
1.126     brouard  3568: }
                   3569: 
                   3570: /*************** log-likelihood *************/
                   3571: double funcone( double *x)
                   3572: {
1.228     brouard  3573:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3574:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3575:   int ioffset=0;
1.131     brouard  3576:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3577:   double **out;
                   3578:   double lli; /* Individual log likelihood */
                   3579:   double llt;
                   3580:   int s1, s2;
1.228     brouard  3581:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3582: 
1.126     brouard  3583:   double bbh, survp;
1.187     brouard  3584:   double agexact;
1.214     brouard  3585:   double agebegin, ageend;
1.126     brouard  3586:   /*extern weight */
                   3587:   /* We are differentiating ll according to initial status */
                   3588:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3589:   /*for(i=1;i<imx;i++) 
                   3590:     printf(" %d\n",s[4][i]);
                   3591:   */
                   3592:   cov[1]=1.;
                   3593: 
                   3594:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3595:   ioffset=0;
                   3596:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3597:     /* ioffset=2+nagesqr+cptcovage; */
                   3598:     ioffset=2+nagesqr;
1.232     brouard  3599:     /* Fixed */
1.224     brouard  3600:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3601:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3602:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3603:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3604: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3605: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3606: /*    cov[2+6]=covar[2][i]; V2  */
                   3607: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3608: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3609: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3610: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3611: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3612: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3613:     }
1.232     brouard  3614:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3615:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3616:     /* } */
1.231     brouard  3617:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3618:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3619:     /* } */
1.225     brouard  3620:     
1.233     brouard  3621: 
                   3622:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3623:     /* Wave varying (but not age varying) */
                   3624:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3625:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3626:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3627:       }
1.232     brouard  3628:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3629:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3630:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3631:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3632:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3633:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3634:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3635:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3636:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3637:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3638:       /* } */
1.126     brouard  3639:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3640:        for (j=1;j<=nlstate+ndeath;j++){
                   3641:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3642:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3643:        }
1.214     brouard  3644:       
                   3645:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3646:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3647:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3648:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3649:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3650:          and mw[mi+1][i]. dh depends on stepm.*/
                   3651:        newm=savm;
1.247     brouard  3652:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3653:        cov[2]=agexact;
                   3654:        if(nagesqr==1)
                   3655:          cov[3]= agexact*agexact;
                   3656:        for (kk=1; kk<=cptcovage;kk++) {
                   3657:          if(!FixedV[Tvar[Tage[kk]]])
                   3658:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3659:          else
                   3660:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3661:        }
                   3662:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3663:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3664:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3665:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3666:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3667:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3668:        savm=oldm;
                   3669:        oldm=newm;
1.126     brouard  3670:       } /* end mult */
                   3671:       
                   3672:       s1=s[mw[mi][i]][i];
                   3673:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3674:       /* if(s2==-1){ */
                   3675:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3676:       /*       /\* exit(1); *\/ */
                   3677:       /* } */
1.126     brouard  3678:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3679:       /* bias is positive if real duration
                   3680:        * is higher than the multiple of stepm and negative otherwise.
                   3681:        */
                   3682:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3683:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3684:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3685:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3686:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3687:        lli= log(survp);
1.126     brouard  3688:       }else if (mle==1){
1.242     brouard  3689:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3690:       } else if(mle==2){
1.242     brouard  3691:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3692:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3693:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3694:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3695:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3696:       } else{  /* mle=0 back to 1 */
1.242     brouard  3697:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3698:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3699:       } /* End of if */
                   3700:       ipmx +=1;
                   3701:       sw += weight[i];
                   3702:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3703:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3704:       if(globpr){
1.246     brouard  3705:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3706:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3707:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3708:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3709:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3710:          llt +=ll[k]*gipmx/gsw;
                   3711:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3712:        }
                   3713:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3714:       }
1.232     brouard  3715:        } /* end of wave */
                   3716: } /* end of individual */
                   3717: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3718: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3719: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3720: if(globpr==0){ /* First time we count the contributions and weights */
                   3721:        gipmx=ipmx;
                   3722:        gsw=sw;
                   3723: }
                   3724: return -l;
1.126     brouard  3725: }
                   3726: 
                   3727: 
                   3728: /*************** function likelione ***********/
                   3729: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3730: {
                   3731:   /* This routine should help understanding what is done with 
                   3732:      the selection of individuals/waves and
                   3733:      to check the exact contribution to the likelihood.
                   3734:      Plotting could be done.
                   3735:    */
                   3736:   int k;
                   3737: 
                   3738:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3739:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3740:     strcat(fileresilk,fileresu);
1.126     brouard  3741:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3742:       printf("Problem with resultfile: %s\n", fileresilk);
                   3743:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3744:     }
1.214     brouard  3745:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3746:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3747:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3748:     for(k=1; k<=nlstate; k++) 
                   3749:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3750:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3751:   }
                   3752: 
                   3753:   *fretone=(*funcone)(p);
                   3754:   if(*globpri !=0){
                   3755:     fclose(ficresilk);
1.205     brouard  3756:     if (mle ==0)
                   3757:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3758:     else if(mle >=1)
                   3759:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3760:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3761:     
1.208     brouard  3762:       
                   3763:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3764:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3765: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3766:     }
1.207     brouard  3767:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3768: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3769:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3770: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3771:     fflush(fichtm);
1.205     brouard  3772:   }
1.126     brouard  3773:   return;
                   3774: }
                   3775: 
                   3776: 
                   3777: /*********** Maximum Likelihood Estimation ***************/
                   3778: 
                   3779: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3780: {
1.165     brouard  3781:   int i,j, iter=0;
1.126     brouard  3782:   double **xi;
                   3783:   double fret;
                   3784:   double fretone; /* Only one call to likelihood */
                   3785:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3786: 
                   3787: #ifdef NLOPT
                   3788:   int creturn;
                   3789:   nlopt_opt opt;
                   3790:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3791:   double *lb;
                   3792:   double minf; /* the minimum objective value, upon return */
                   3793:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3794:   myfunc_data dinst, *d = &dinst;
                   3795: #endif
                   3796: 
                   3797: 
1.126     brouard  3798:   xi=matrix(1,npar,1,npar);
                   3799:   for (i=1;i<=npar;i++)
                   3800:     for (j=1;j<=npar;j++)
                   3801:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3802:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3803:   strcpy(filerespow,"POW_"); 
1.126     brouard  3804:   strcat(filerespow,fileres);
                   3805:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3806:     printf("Problem with resultfile: %s\n", filerespow);
                   3807:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3808:   }
                   3809:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3810:   for (i=1;i<=nlstate;i++)
                   3811:     for(j=1;j<=nlstate+ndeath;j++)
                   3812:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3813:   fprintf(ficrespow,"\n");
1.162     brouard  3814: #ifdef POWELL
1.126     brouard  3815:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3816: #endif
1.126     brouard  3817: 
1.162     brouard  3818: #ifdef NLOPT
                   3819: #ifdef NEWUOA
                   3820:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3821: #else
                   3822:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3823: #endif
                   3824:   lb=vector(0,npar-1);
                   3825:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3826:   nlopt_set_lower_bounds(opt, lb);
                   3827:   nlopt_set_initial_step1(opt, 0.1);
                   3828:   
                   3829:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3830:   d->function = func;
                   3831:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3832:   nlopt_set_min_objective(opt, myfunc, d);
                   3833:   nlopt_set_xtol_rel(opt, ftol);
                   3834:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3835:     printf("nlopt failed! %d\n",creturn); 
                   3836:   }
                   3837:   else {
                   3838:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3839:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3840:     iter=1; /* not equal */
                   3841:   }
                   3842:   nlopt_destroy(opt);
                   3843: #endif
1.126     brouard  3844:   free_matrix(xi,1,npar,1,npar);
                   3845:   fclose(ficrespow);
1.203     brouard  3846:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3847:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3848:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3849: 
                   3850: }
                   3851: 
                   3852: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3853: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3854: {
                   3855:   double  **a,**y,*x,pd;
1.203     brouard  3856:   /* double **hess; */
1.164     brouard  3857:   int i, j;
1.126     brouard  3858:   int *indx;
                   3859: 
                   3860:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3861:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3862:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3863:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3864:   double gompertz(double p[]);
1.203     brouard  3865:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3866: 
                   3867:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3868:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3869:   for (i=1;i<=npar;i++){
1.203     brouard  3870:     printf("%d-",i);fflush(stdout);
                   3871:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3872:    
                   3873:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3874:     
                   3875:     /*  printf(" %f ",p[i]);
                   3876:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3877:   }
                   3878:   
                   3879:   for (i=1;i<=npar;i++) {
                   3880:     for (j=1;j<=npar;j++)  {
                   3881:       if (j>i) { 
1.203     brouard  3882:        printf(".%d-%d",i,j);fflush(stdout);
                   3883:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3884:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3885:        
                   3886:        hess[j][i]=hess[i][j];    
                   3887:        /*printf(" %lf ",hess[i][j]);*/
                   3888:       }
                   3889:     }
                   3890:   }
                   3891:   printf("\n");
                   3892:   fprintf(ficlog,"\n");
                   3893: 
                   3894:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3895:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3896:   
                   3897:   a=matrix(1,npar,1,npar);
                   3898:   y=matrix(1,npar,1,npar);
                   3899:   x=vector(1,npar);
                   3900:   indx=ivector(1,npar);
                   3901:   for (i=1;i<=npar;i++)
                   3902:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3903:   ludcmp(a,npar,indx,&pd);
                   3904: 
                   3905:   for (j=1;j<=npar;j++) {
                   3906:     for (i=1;i<=npar;i++) x[i]=0;
                   3907:     x[j]=1;
                   3908:     lubksb(a,npar,indx,x);
                   3909:     for (i=1;i<=npar;i++){ 
                   3910:       matcov[i][j]=x[i];
                   3911:     }
                   3912:   }
                   3913: 
                   3914:   printf("\n#Hessian matrix#\n");
                   3915:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3916:   for (i=1;i<=npar;i++) { 
                   3917:     for (j=1;j<=npar;j++) { 
1.203     brouard  3918:       printf("%.6e ",hess[i][j]);
                   3919:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3920:     }
                   3921:     printf("\n");
                   3922:     fprintf(ficlog,"\n");
                   3923:   }
                   3924: 
1.203     brouard  3925:   /* printf("\n#Covariance matrix#\n"); */
                   3926:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3927:   /* for (i=1;i<=npar;i++) {  */
                   3928:   /*   for (j=1;j<=npar;j++) {  */
                   3929:   /*     printf("%.6e ",matcov[i][j]); */
                   3930:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3931:   /*   } */
                   3932:   /*   printf("\n"); */
                   3933:   /*   fprintf(ficlog,"\n"); */
                   3934:   /* } */
                   3935: 
1.126     brouard  3936:   /* Recompute Inverse */
1.203     brouard  3937:   /* for (i=1;i<=npar;i++) */
                   3938:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3939:   /* ludcmp(a,npar,indx,&pd); */
                   3940: 
                   3941:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3942: 
                   3943:   /* for (j=1;j<=npar;j++) { */
                   3944:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3945:   /*   x[j]=1; */
                   3946:   /*   lubksb(a,npar,indx,x); */
                   3947:   /*   for (i=1;i<=npar;i++){  */
                   3948:   /*     y[i][j]=x[i]; */
                   3949:   /*     printf("%.3e ",y[i][j]); */
                   3950:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3951:   /*   } */
                   3952:   /*   printf("\n"); */
                   3953:   /*   fprintf(ficlog,"\n"); */
                   3954:   /* } */
                   3955: 
                   3956:   /* Verifying the inverse matrix */
                   3957: #ifdef DEBUGHESS
                   3958:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3959: 
1.203     brouard  3960:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3961:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3962: 
                   3963:   for (j=1;j<=npar;j++) {
                   3964:     for (i=1;i<=npar;i++){ 
1.203     brouard  3965:       printf("%.2f ",y[i][j]);
                   3966:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3967:     }
                   3968:     printf("\n");
                   3969:     fprintf(ficlog,"\n");
                   3970:   }
1.203     brouard  3971: #endif
1.126     brouard  3972: 
                   3973:   free_matrix(a,1,npar,1,npar);
                   3974:   free_matrix(y,1,npar,1,npar);
                   3975:   free_vector(x,1,npar);
                   3976:   free_ivector(indx,1,npar);
1.203     brouard  3977:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3978: 
                   3979: 
                   3980: }
                   3981: 
                   3982: /*************** hessian matrix ****************/
                   3983: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3984: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3985:   int i;
                   3986:   int l=1, lmax=20;
1.203     brouard  3987:   double k1,k2, res, fx;
1.132     brouard  3988:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3989:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3990:   int k=0,kmax=10;
                   3991:   double l1;
                   3992: 
                   3993:   fx=func(x);
                   3994:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  3995:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  3996:     l1=pow(10,l);
                   3997:     delts=delt;
                   3998:     for(k=1 ; k <kmax; k=k+1){
                   3999:       delt = delta*(l1*k);
                   4000:       p2[theta]=x[theta] +delt;
1.145     brouard  4001:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4002:       p2[theta]=x[theta]-delt;
                   4003:       k2=func(p2)-fx;
                   4004:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4005:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4006:       
1.203     brouard  4007: #ifdef DEBUGHESSII
1.126     brouard  4008:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4009:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4010: #endif
                   4011:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4012:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4013:        k=kmax;
                   4014:       }
                   4015:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4016:        k=kmax; l=lmax*10;
1.126     brouard  4017:       }
                   4018:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4019:        delts=delt;
                   4020:       }
1.203     brouard  4021:     } /* End loop k */
1.126     brouard  4022:   }
                   4023:   delti[theta]=delts;
                   4024:   return res; 
                   4025:   
                   4026: }
                   4027: 
1.203     brouard  4028: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4029: {
                   4030:   int i;
1.164     brouard  4031:   int l=1, lmax=20;
1.126     brouard  4032:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4033:   double p2[MAXPARM+1];
1.203     brouard  4034:   int k, kmax=1;
                   4035:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4036: 
                   4037:   int firstime=0;
1.203     brouard  4038:   
1.126     brouard  4039:   fx=func(x);
1.203     brouard  4040:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4041:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4042:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4043:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4044:     k1=func(p2)-fx;
                   4045:   
1.203     brouard  4046:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4047:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4048:     k2=func(p2)-fx;
                   4049:   
1.203     brouard  4050:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4051:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4052:     k3=func(p2)-fx;
                   4053:   
1.203     brouard  4054:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4055:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4056:     k4=func(p2)-fx;
1.203     brouard  4057:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4058:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4059:       firstime=1;
1.203     brouard  4060:       kmax=kmax+10;
1.208     brouard  4061:     }
                   4062:     if(kmax >=10 || firstime ==1){
1.246     brouard  4063:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4064:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4065:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4066:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4067:     }
                   4068: #ifdef DEBUGHESSIJ
                   4069:     v1=hess[thetai][thetai];
                   4070:     v2=hess[thetaj][thetaj];
                   4071:     cv12=res;
                   4072:     /* Computing eigen value of Hessian matrix */
                   4073:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4074:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4075:     if ((lc2 <0) || (lc1 <0) ){
                   4076:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4077:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4078:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4079:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4080:     }
1.126     brouard  4081: #endif
                   4082:   }
                   4083:   return res;
                   4084: }
                   4085: 
1.203     brouard  4086:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4087: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4088: /* { */
                   4089: /*   int i; */
                   4090: /*   int l=1, lmax=20; */
                   4091: /*   double k1,k2,k3,k4,res,fx; */
                   4092: /*   double p2[MAXPARM+1]; */
                   4093: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4094: /*   int k=0,kmax=10; */
                   4095: /*   double l1; */
                   4096:   
                   4097: /*   fx=func(x); */
                   4098: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4099: /*     l1=pow(10,l); */
                   4100: /*     delts=delt; */
                   4101: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4102: /*       delt = delti*(l1*k); */
                   4103: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4104: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4105: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4106: /*       k1=func(p2)-fx; */
                   4107:       
                   4108: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4109: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4110: /*       k2=func(p2)-fx; */
                   4111:       
                   4112: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4113: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4114: /*       k3=func(p2)-fx; */
                   4115:       
                   4116: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4117: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4118: /*       k4=func(p2)-fx; */
                   4119: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4120: /* #ifdef DEBUGHESSIJ */
                   4121: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4122: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4123: /* #endif */
                   4124: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4125: /*     k=kmax; */
                   4126: /*       } */
                   4127: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4128: /*     k=kmax; l=lmax*10; */
                   4129: /*       } */
                   4130: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4131: /*     delts=delt; */
                   4132: /*       } */
                   4133: /*     } /\* End loop k *\/ */
                   4134: /*   } */
                   4135: /*   delti[theta]=delts; */
                   4136: /*   return res;  */
                   4137: /* } */
                   4138: 
                   4139: 
1.126     brouard  4140: /************** Inverse of matrix **************/
                   4141: void ludcmp(double **a, int n, int *indx, double *d) 
                   4142: { 
                   4143:   int i,imax,j,k; 
                   4144:   double big,dum,sum,temp; 
                   4145:   double *vv; 
                   4146:  
                   4147:   vv=vector(1,n); 
                   4148:   *d=1.0; 
                   4149:   for (i=1;i<=n;i++) { 
                   4150:     big=0.0; 
                   4151:     for (j=1;j<=n;j++) 
                   4152:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4153:     if (big == 0.0){
                   4154:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4155:       for (j=1;j<=n;j++) {
                   4156:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4157:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4158:       }
                   4159:       fflush(ficlog);
                   4160:       fclose(ficlog);
                   4161:       nrerror("Singular matrix in routine ludcmp"); 
                   4162:     }
1.126     brouard  4163:     vv[i]=1.0/big; 
                   4164:   } 
                   4165:   for (j=1;j<=n;j++) { 
                   4166:     for (i=1;i<j;i++) { 
                   4167:       sum=a[i][j]; 
                   4168:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4169:       a[i][j]=sum; 
                   4170:     } 
                   4171:     big=0.0; 
                   4172:     for (i=j;i<=n;i++) { 
                   4173:       sum=a[i][j]; 
                   4174:       for (k=1;k<j;k++) 
                   4175:        sum -= a[i][k]*a[k][j]; 
                   4176:       a[i][j]=sum; 
                   4177:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4178:        big=dum; 
                   4179:        imax=i; 
                   4180:       } 
                   4181:     } 
                   4182:     if (j != imax) { 
                   4183:       for (k=1;k<=n;k++) { 
                   4184:        dum=a[imax][k]; 
                   4185:        a[imax][k]=a[j][k]; 
                   4186:        a[j][k]=dum; 
                   4187:       } 
                   4188:       *d = -(*d); 
                   4189:       vv[imax]=vv[j]; 
                   4190:     } 
                   4191:     indx[j]=imax; 
                   4192:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4193:     if (j != n) { 
                   4194:       dum=1.0/(a[j][j]); 
                   4195:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4196:     } 
                   4197:   } 
                   4198:   free_vector(vv,1,n);  /* Doesn't work */
                   4199: ;
                   4200: } 
                   4201: 
                   4202: void lubksb(double **a, int n, int *indx, double b[]) 
                   4203: { 
                   4204:   int i,ii=0,ip,j; 
                   4205:   double sum; 
                   4206:  
                   4207:   for (i=1;i<=n;i++) { 
                   4208:     ip=indx[i]; 
                   4209:     sum=b[ip]; 
                   4210:     b[ip]=b[i]; 
                   4211:     if (ii) 
                   4212:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4213:     else if (sum) ii=i; 
                   4214:     b[i]=sum; 
                   4215:   } 
                   4216:   for (i=n;i>=1;i--) { 
                   4217:     sum=b[i]; 
                   4218:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4219:     b[i]=sum/a[i][i]; 
                   4220:   } 
                   4221: } 
                   4222: 
                   4223: void pstamp(FILE *fichier)
                   4224: {
1.196     brouard  4225:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4226: }
                   4227: 
1.253     brouard  4228: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4229: 
                   4230:   /* y=a+bx regression */
                   4231:   double   sumx = 0.0;                        /* sum of x                      */
                   4232:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4233:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4234:   double   sumy = 0.0;                        /* sum of y                      */
                   4235:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4236:   double   sume2; /* sum of square or residuals */
                   4237:   double yhat;
                   4238:   
                   4239:   double denom=0;
                   4240:   int i;
                   4241:   int ne=*no;
                   4242:   
                   4243:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4244:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4245:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4246:       continue;
                   4247:     }
                   4248:     ne=ne+1;
                   4249:     sumx  += x[i];       
                   4250:     sumx2 += x[i]*x[i];  
                   4251:     sumxy += x[i] * y[i];
                   4252:     sumy  += y[i];      
                   4253:     sumy2 += y[i]*y[i]; 
                   4254:     denom = (ne * sumx2 - sumx*sumx);
                   4255:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4256:   } 
                   4257:   
                   4258:   denom = (ne * sumx2 - sumx*sumx);
                   4259:   if (denom == 0) {
                   4260:     // vertical, slope m is infinity
                   4261:     *b = INFINITY;
                   4262:     *a = 0;
                   4263:     if (r) *r = 0;
                   4264:     return 1;
                   4265:   }
                   4266:   
                   4267:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4268:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4269:   if (r!=NULL) {
                   4270:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4271:       sqrt((sumx2 - sumx*sumx/ne) *
                   4272:           (sumy2 - sumy*sumy/ne));
                   4273:   }
                   4274:   *no=ne;
                   4275:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4276:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4277:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4278:       continue;
                   4279:     }
                   4280:     ne=ne+1;
                   4281:     yhat = y[i] - *a -*b* x[i];
                   4282:     sume2  += yhat * yhat ;       
                   4283:     
                   4284:     denom = (ne * sumx2 - sumx*sumx);
                   4285:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4286:   } 
                   4287:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4288:   *sa= *sb * sqrt(sumx2/ne);
                   4289:   
                   4290:   return 0; 
                   4291: }
                   4292: 
1.126     brouard  4293: /************ Frequencies ********************/
1.251     brouard  4294: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4295:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4296:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4297: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4298:   
1.253     brouard  4299:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4300:   int iind=0, iage=0;
                   4301:   int mi; /* Effective wave */
                   4302:   int first;
                   4303:   double ***freq; /* Frequencies */
1.253     brouard  4304:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4305:   int no;
1.226     brouard  4306:   double *meanq;
                   4307:   double **meanqt;
                   4308:   double *pp, **prop, *posprop, *pospropt;
                   4309:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4310:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4311:   double agebegin, ageend;
                   4312:     
                   4313:   pp=vector(1,nlstate);
1.251     brouard  4314:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4315:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4316:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4317:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4318:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4319:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4320:   strcpy(fileresp,"P_");
                   4321:   strcat(fileresp,fileresu);
                   4322:   /*strcat(fileresphtm,fileresu);*/
                   4323:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4324:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4325:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4326:     exit(0);
                   4327:   }
1.240     brouard  4328:   
1.226     brouard  4329:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4330:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4331:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4332:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4333:     fflush(ficlog);
                   4334:     exit(70); 
                   4335:   }
                   4336:   else{
                   4337:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4338: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4339: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4340:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4341:   }
1.237     brouard  4342:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4343:   
1.226     brouard  4344:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4345:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4346:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4347:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4348:     fflush(ficlog);
                   4349:     exit(70); 
1.240     brouard  4350:   } else{
1.226     brouard  4351:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4352: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4353: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4354:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4355:   }
1.240     brouard  4356:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4357:   
1.253     brouard  4358:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4359:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4360:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4361:   j1=0;
1.126     brouard  4362:   
1.227     brouard  4363:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4364:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4365:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4366:   
                   4367:   
1.226     brouard  4368:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4369:      reference=low_education V1=0,V2=0
                   4370:      med_educ                V1=1 V2=0, 
                   4371:      high_educ               V1=0 V2=1
                   4372:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4373:   */
1.249     brouard  4374:   dateintsum=0;
                   4375:   k2cpt=0;
                   4376: 
1.253     brouard  4377:   if(cptcoveff == 0 )
                   4378:     nl=1;  /* Constant model only */
                   4379:   else
                   4380:     nl=2;
                   4381:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4382:     if(nj==1)
                   4383:       j=0;  /* First pass for the constant */
                   4384:     else
                   4385:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4386:     first=1;
                   4387:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4388:       posproptt=0.;
                   4389:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4390:        scanf("%d", i);*/
                   4391:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4392:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4393:          for(m=iagemin; m <= iagemax+3; m++)
                   4394:            freq[i][jk][m]=0;
                   4395:       
                   4396:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4397:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4398:          prop[i][m]=0;
                   4399:        posprop[i]=0;
                   4400:        pospropt[i]=0;
                   4401:       }
                   4402:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4403:       /*   meanq[z1]+=0.; */
                   4404:       /*   for(m=1;m<=lastpass;m++){ */
                   4405:       /*       meanqt[m][z1]=0.; */
                   4406:       /*   } */
                   4407:       /* } */
                   4408:       
                   4409:       /* dateintsum=0; */
                   4410:       /* k2cpt=0; */
                   4411:       
                   4412:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4413:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4414:        bool=1;
                   4415:        if(j !=0){
                   4416:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4417:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4418:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4419:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4420:              /* } */
                   4421:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4422:                /* if(Tvaraff[z1] ==-20){ */
                   4423:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4424:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4425:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4426:                /* }else  */
                   4427:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4428:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4429:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4430:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4431:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4432:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4433:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4434:                } /* Onlyf fixed */
                   4435:              } /* end z1 */
                   4436:            } /* cptcovn > 0 */
                   4437:          } /* end any */
                   4438:        }/* end j==0 */
                   4439:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4440:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4441:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4442:            m=mw[mi][iind];
                   4443:            if(j!=0){
                   4444:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4445:                for (z1=1; z1<=cptcoveff; z1++) {
                   4446:                  if( Fixed[Tmodelind[z1]]==1){
                   4447:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4448:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4449:                                                                                      value is -1, we don't select. It differs from the 
                   4450:                                                                                      constant and age model which counts them. */
                   4451:                      bool=0; /* not selected */
                   4452:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4453:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4454:                      bool=0;
                   4455:                    }
                   4456:                  }
                   4457:                }
                   4458:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4459:            } /* end j==0 */
                   4460:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4461:            if(bool==1){
                   4462:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4463:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4464:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4465:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4466:              if(m >=firstpass && m <=lastpass){
                   4467:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4468:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4469:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4470:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4471:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4472:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4473:                if (m<lastpass) {
                   4474:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4475:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4476:                  if(s[m][iind]==-1)
                   4477:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4478:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4479:                  /* if((int)agev[m][iind] == 55) */
                   4480:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4481:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4482:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4483:                }
1.251     brouard  4484:              } /* end if between passes */  
                   4485:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4486:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4487:                k2cpt++;
                   4488:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4489:              }
1.251     brouard  4490:            }else{
                   4491:              bool=1;
                   4492:            }/* end bool 2 */
                   4493:          } /* end m */
                   4494:        } /* end bool */
                   4495:       } /* end iind = 1 to imx */
                   4496:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4497:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4498:       
                   4499:       
                   4500:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4501:       pstamp(ficresp);
                   4502:       if  (cptcoveff>0 && j!=0){
                   4503:        printf( "\n#********** Variable "); 
                   4504:        fprintf(ficresp, "\n#********** Variable "); 
                   4505:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4506:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4507:        fprintf(ficlog, "\n#********** Variable "); 
                   4508:        for (z1=1; z1<=cptcoveff; z1++){
                   4509:          if(!FixedV[Tvaraff[z1]]){
                   4510:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4511:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4512:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4513:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4514:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4515:          }else{
1.251     brouard  4516:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4517:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4518:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4519:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4520:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4521:          }
                   4522:        }
                   4523:        printf( "**********\n#");
                   4524:        fprintf(ficresp, "**********\n#");
                   4525:        fprintf(ficresphtm, "**********</h3>\n");
                   4526:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4527:        fprintf(ficlog, "**********\n");
                   4528:       }
                   4529:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4530:       for(i=1; i<=nlstate;i++) {
                   4531:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4532:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4533:       }
                   4534:       fprintf(ficresp, "\n");
                   4535:       fprintf(ficresphtm, "\n");
                   4536:       
                   4537:       /* Header of frequency table by age */
                   4538:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4539:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4540:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4541:        for(m=-1; m <=nlstate+ndeath; m++){
                   4542:          if(jk!=0 && m!=0)
                   4543:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4544:        }
1.226     brouard  4545:       }
1.251     brouard  4546:       fprintf(ficresphtmfr, "\n");
                   4547:     
                   4548:       /* For each age */
                   4549:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4550:        fprintf(ficresphtm,"<tr>");
                   4551:        if(iage==iagemax+1){
                   4552:          fprintf(ficlog,"1");
                   4553:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4554:        }else if(iage==iagemax+2){
                   4555:          fprintf(ficlog,"0");
                   4556:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4557:        }else if(iage==iagemax+3){
                   4558:          fprintf(ficlog,"Total");
                   4559:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4560:        }else{
1.240     brouard  4561:          if(first==1){
1.251     brouard  4562:            first=0;
                   4563:            printf("See log file for details...\n");
                   4564:          }
                   4565:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4566:          fprintf(ficlog,"Age %d", iage);
                   4567:        }
                   4568:        for(jk=1; jk <=nlstate ; jk++){
                   4569:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4570:            pp[jk] += freq[jk][m][iage]; 
                   4571:        }
                   4572:        for(jk=1; jk <=nlstate ; jk++){
                   4573:          for(m=-1, pos=0; m <=0 ; m++)
                   4574:            pos += freq[jk][m][iage];
                   4575:          if(pp[jk]>=1.e-10){
                   4576:            if(first==1){
                   4577:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4578:            }
                   4579:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4580:          }else{
                   4581:            if(first==1)
                   4582:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4583:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4584:          }
                   4585:        }
                   4586:       
1.251     brouard  4587:        for(jk=1; jk <=nlstate ; jk++){ 
                   4588:          /* posprop[jk]=0; */
                   4589:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4590:            pp[jk] += freq[jk][m][iage];
                   4591:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4592:       
                   4593:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4594:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4595:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4596:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4597:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4598:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4599:        }
1.251     brouard  4600:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4601:          if(pos>=1.e-5){
1.251     brouard  4602:            if(first==1)
                   4603:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4604:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4605:          }else{
                   4606:            if(first==1)
                   4607:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4608:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4609:          }
                   4610:          if( iage <= iagemax){
                   4611:            if(pos>=1.e-5){
                   4612:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4613:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4614:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4615:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4616:            }
                   4617:            else{
                   4618:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4619:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4620:            }
1.240     brouard  4621:          }
1.251     brouard  4622:          pospropt[jk] +=posprop[jk];
                   4623:        } /* end loop jk */
                   4624:        /* pospropt=0.; */
                   4625:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4626:          for(m=-1; m <=nlstate+ndeath; m++){
                   4627:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4628:              if(first==1){
                   4629:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4630:              }
1.253     brouard  4631:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4632:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4633:            }
                   4634:            if(jk!=0 && m!=0)
                   4635:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4636:          }
1.251     brouard  4637:        } /* end loop jk */
                   4638:        posproptt=0.; 
                   4639:        for(jk=1; jk <=nlstate; jk++){
                   4640:          posproptt += pospropt[jk];
                   4641:        }
                   4642:        fprintf(ficresphtmfr,"</tr>\n ");
                   4643:        if(iage <= iagemax){
                   4644:          fprintf(ficresp,"\n");
                   4645:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4646:        }
1.251     brouard  4647:        if(first==1)
                   4648:          printf("Others in log...\n");
                   4649:        fprintf(ficlog,"\n");
                   4650:       } /* end loop age iage */
                   4651:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4652:       for(jk=1; jk <=nlstate ; jk++){
                   4653:        if(posproptt < 1.e-5){
                   4654:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4655:        }else{
                   4656:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4657:        }
1.226     brouard  4658:       }
1.251     brouard  4659:       fprintf(ficresphtm,"</tr>\n");
                   4660:       fprintf(ficresphtm,"</table>\n");
                   4661:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4662:       if(posproptt < 1.e-5){
1.251     brouard  4663:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4664:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4665:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4666:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4667:        invalidvarcomb[j1]=1;
1.226     brouard  4668:       }else{
1.251     brouard  4669:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4670:        invalidvarcomb[j1]=0;
1.226     brouard  4671:       }
1.251     brouard  4672:       fprintf(ficresphtmfr,"</table>\n");
                   4673:       fprintf(ficlog,"\n");
                   4674:       if(j!=0){
                   4675:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4676:        for(i=1,jk=1; i <=nlstate; i++){
                   4677:          for(k=1; k <=(nlstate+ndeath); k++){
                   4678:            if (k != i) {
                   4679:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4680:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4681:                  if(j1==1){ /* All dummy covariates to zero */
                   4682:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4683:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4684:                    printf("%d%d ",i,k);
                   4685:                    fprintf(ficlog,"%d%d ",i,k);
                   4686:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4687:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4688:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4689:                  }
1.253     brouard  4690:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4691:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4692:                    x[iage]= (double)iage;
                   4693:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4694:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4695:                  }
                   4696:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4697:                  pstart[jk]=b;
                   4698:                  pstart[jk-1]=a;
1.252     brouard  4699:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4700:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4701:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4702:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4703:                  printf("%d%d ",i,k);
                   4704:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4705:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4706:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4707:                  ;
                   4708:                }
                   4709:                /* printf("%12.7f )", param[i][jj][k]); */
                   4710:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4711:                jk++; 
                   4712:              } /* end jj */
                   4713:            } /* end k!= i */
                   4714:          } /* end k */
                   4715:        } /* end i, jk */
                   4716:       } /* end j !=0 */
                   4717:     } /* end selected combination of covariate j1 */
                   4718:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4719:       printf("#Freqsummary: Starting values for the constants:\n");
                   4720:       fprintf(ficlog,"\n");
                   4721:       for(i=1,jk=1; i <=nlstate; i++){
                   4722:        for(k=1; k <=(nlstate+ndeath); k++){
                   4723:          if (k != i) {
                   4724:            printf("%d%d ",i,k);
                   4725:            fprintf(ficlog,"%d%d ",i,k);
                   4726:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4727:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4728:              if(jj==1){ /* Age has to be done */
                   4729:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4730:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4731:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4732:              }
                   4733:              /* printf("%12.7f )", param[i][jj][k]); */
                   4734:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4735:              jk++; 
1.250     brouard  4736:            }
1.251     brouard  4737:            printf("\n");
                   4738:            fprintf(ficlog,"\n");
1.250     brouard  4739:          }
                   4740:        }
                   4741:       }
1.251     brouard  4742:       printf("#Freqsummary\n");
                   4743:       fprintf(ficlog,"\n");
                   4744:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4745:        for(m=-1; m <=nlstate+ndeath; m++){
                   4746:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4747:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4748:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4749:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4750:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4751:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4752:          /* } */
                   4753:        }
                   4754:       } /* end loop jk */
                   4755:       
                   4756:       printf("\n");
                   4757:       fprintf(ficlog,"\n");
                   4758:     } /* end j=0 */
1.249     brouard  4759:   } /* end j */
1.252     brouard  4760: 
1.253     brouard  4761:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4762:     for(i=1, jk=1; i <=nlstate; i++){
                   4763:       for(j=1; j <=nlstate+ndeath; j++){
                   4764:        if(j!=i){
                   4765:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4766:          printf("%1d%1d",i,j);
                   4767:          fprintf(ficparo,"%1d%1d",i,j);
                   4768:          for(k=1; k<=ncovmodel;k++){
                   4769:            /*    printf(" %lf",param[i][j][k]); */
                   4770:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4771:            p[jk]=pstart[jk];
                   4772:            printf(" %f ",pstart[jk]);
                   4773:            fprintf(ficparo," %f ",pstart[jk]);
                   4774:            jk++;
                   4775:          }
                   4776:          printf("\n");
                   4777:          fprintf(ficparo,"\n");
                   4778:        }
                   4779:       }
                   4780:     }
                   4781:   } /* end mle=-2 */
1.226     brouard  4782:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4783:   
1.226     brouard  4784:   fclose(ficresp);
                   4785:   fclose(ficresphtm);
                   4786:   fclose(ficresphtmfr);
                   4787:   free_vector(meanq,1,nqfveff);
                   4788:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4789:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4790:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4791:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4792:   free_vector(pospropt,1,nlstate);
                   4793:   free_vector(posprop,1,nlstate);
1.251     brouard  4794:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4795:   free_vector(pp,1,nlstate);
                   4796:   /* End of freqsummary */
                   4797: }
1.126     brouard  4798: 
                   4799: /************ Prevalence ********************/
1.227     brouard  4800: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4801: {  
                   4802:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4803:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4804:      We still use firstpass and lastpass as another selection.
                   4805:   */
1.126     brouard  4806:  
1.227     brouard  4807:   int i, m, jk, j1, bool, z1,j, iv;
                   4808:   int mi; /* Effective wave */
                   4809:   int iage;
                   4810:   double agebegin, ageend;
                   4811: 
                   4812:   double **prop;
                   4813:   double posprop; 
                   4814:   double  y2; /* in fractional years */
                   4815:   int iagemin, iagemax;
                   4816:   int first; /** to stop verbosity which is redirected to log file */
                   4817: 
                   4818:   iagemin= (int) agemin;
                   4819:   iagemax= (int) agemax;
                   4820:   /*pp=vector(1,nlstate);*/
1.251     brouard  4821:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4822:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4823:   j1=0;
1.222     brouard  4824:   
1.227     brouard  4825:   /*j=cptcoveff;*/
                   4826:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4827:   
1.227     brouard  4828:   first=1;
                   4829:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4830:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4831:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4832:        prop[i][iage]=0.0;
                   4833:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4834:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4835:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4836:     
                   4837:     for (i=1; i<=imx; i++) { /* Each individual */
                   4838:       bool=1;
                   4839:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4840:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4841:        m=mw[mi][i];
                   4842:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4843:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4844:        for (z1=1; z1<=cptcoveff; z1++){
                   4845:          if( Fixed[Tmodelind[z1]]==1){
                   4846:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4847:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4848:              bool=0;
                   4849:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4850:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4851:              bool=0;
                   4852:            }
                   4853:        }
                   4854:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4855:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4856:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4857:          if(m >=firstpass && m <=lastpass){
                   4858:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4859:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4860:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4861:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4862:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4863:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4864:                exit(1);
                   4865:              }
                   4866:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4867:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4868:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4869:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4870:              } /* end valid statuses */ 
                   4871:            } /* end selection of dates */
                   4872:          } /* end selection of waves */
                   4873:        } /* end bool */
                   4874:       } /* end wave */
                   4875:     } /* end individual */
                   4876:     for(i=iagemin; i <= iagemax+3; i++){  
                   4877:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4878:        posprop += prop[jk][i]; 
                   4879:       } 
                   4880:       
                   4881:       for(jk=1; jk <=nlstate ; jk++){      
                   4882:        if( i <=  iagemax){ 
                   4883:          if(posprop>=1.e-5){ 
                   4884:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4885:          } else{
                   4886:            if(first==1){
                   4887:              first=0;
                   4888:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4889:            }
                   4890:          }
                   4891:        } 
                   4892:       }/* end jk */ 
                   4893:     }/* end i */ 
1.222     brouard  4894:      /*} *//* end i1 */
1.227     brouard  4895:   } /* end j1 */
1.222     brouard  4896:   
1.227     brouard  4897:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4898:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4899:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4900: }  /* End of prevalence */
1.126     brouard  4901: 
                   4902: /************* Waves Concatenation ***************/
                   4903: 
                   4904: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4905: {
                   4906:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4907:      Death is a valid wave (if date is known).
                   4908:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4909:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4910:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4911:   */
1.126     brouard  4912: 
1.224     brouard  4913:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4914:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4915:      double sum=0., jmean=0.;*/
1.224     brouard  4916:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4917:   int j, k=0,jk, ju, jl;
                   4918:   double sum=0.;
                   4919:   first=0;
1.214     brouard  4920:   firstwo=0;
1.217     brouard  4921:   firsthree=0;
1.218     brouard  4922:   firstfour=0;
1.164     brouard  4923:   jmin=100000;
1.126     brouard  4924:   jmax=-1;
                   4925:   jmean=0.;
1.224     brouard  4926: 
                   4927: /* Treating live states */
1.214     brouard  4928:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4929:     mi=0;  /* First valid wave */
1.227     brouard  4930:     mli=0; /* Last valid wave */
1.126     brouard  4931:     m=firstpass;
1.214     brouard  4932:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4933:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4934:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4935:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4936:        mw[++mi][i]=m;
                   4937:        mli=m;
1.224     brouard  4938:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4939:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4940:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4941:       }
1.227     brouard  4942:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4943: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4944:        break;
1.224     brouard  4945: #else
1.227     brouard  4946:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4947:          if(firsthree == 0){
                   4948:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4949:            firsthree=1;
                   4950:          }
                   4951:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as pi. .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m);
                   4952:          mw[++mi][i]=m;
                   4953:          mli=m;
                   4954:        }
                   4955:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4956:          nbwarn++;
                   4957:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4958:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4959:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4960:          }
                   4961:          break;
                   4962:        }
                   4963:        break;
1.224     brouard  4964: #endif
1.227     brouard  4965:       }/* End m >= lastpass */
1.126     brouard  4966:     }/* end while */
1.224     brouard  4967: 
1.227     brouard  4968:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4969:     /* After last pass */
1.224     brouard  4970: /* Treating death states */
1.214     brouard  4971:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4972:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4973:       /* } */
1.126     brouard  4974:       mi++;    /* Death is another wave */
                   4975:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4976:       /* Only death is a correct wave */
1.126     brouard  4977:       mw[mi][i]=m;
1.257     brouard  4978:     } /* else not in a death state */
1.224     brouard  4979: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  4980:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  4981:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4982:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4983:          nbwarn++;
                   4984:          if(firstfiv==0){
                   4985:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4986:            firstfiv=1;
                   4987:          }else{
                   4988:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4989:          }
                   4990:        }else{ /* Death occured afer last wave potential bias */
                   4991:          nberr++;
                   4992:          if(firstwo==0){
1.257     brouard  4993:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  4994:            firstwo=1;
                   4995:          }
1.257     brouard  4996:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  4997:        }
1.257     brouard  4998:       }else{ /* if date of interview is unknown */
1.227     brouard  4999:        /* death is known but not confirmed by death status at any wave */
                   5000:        if(firstfour==0){
                   5001:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5002:          firstfour=1;
                   5003:        }
                   5004:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5005:       }
1.224     brouard  5006:     } /* end if date of death is known */
                   5007: #endif
                   5008:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5009:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5010:     if(mi==0){
                   5011:       nbwarn++;
                   5012:       if(first==0){
1.227     brouard  5013:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5014:        first=1;
1.126     brouard  5015:       }
                   5016:       if(first==1){
1.227     brouard  5017:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5018:       }
                   5019:     } /* end mi==0 */
                   5020:   } /* End individuals */
1.214     brouard  5021:   /* wav and mw are no more changed */
1.223     brouard  5022:        
1.214     brouard  5023:   
1.126     brouard  5024:   for(i=1; i<=imx; i++){
                   5025:     for(mi=1; mi<wav[i];mi++){
                   5026:       if (stepm <=0)
1.227     brouard  5027:        dh[mi][i]=1;
1.126     brouard  5028:       else{
1.260     brouard  5029:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5030:          if (agedc[i] < 2*AGESUP) {
                   5031:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5032:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5033:            else if(j<0){
                   5034:              nberr++;
                   5035:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5036:              j=1; /* Temporary Dangerous patch */
                   5037:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5038:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5039:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5040:            }
                   5041:            k=k+1;
                   5042:            if (j >= jmax){
                   5043:              jmax=j;
                   5044:              ijmax=i;
                   5045:            }
                   5046:            if (j <= jmin){
                   5047:              jmin=j;
                   5048:              ijmin=i;
                   5049:            }
                   5050:            sum=sum+j;
                   5051:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5052:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5053:          }
                   5054:        }
                   5055:        else{
                   5056:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5057: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5058:                                        
1.227     brouard  5059:          k=k+1;
                   5060:          if (j >= jmax) {
                   5061:            jmax=j;
                   5062:            ijmax=i;
                   5063:          }
                   5064:          else if (j <= jmin){
                   5065:            jmin=j;
                   5066:            ijmin=i;
                   5067:          }
                   5068:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5069:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5070:          if(j<0){
                   5071:            nberr++;
                   5072:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5073:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5074:          }
                   5075:          sum=sum+j;
                   5076:        }
                   5077:        jk= j/stepm;
                   5078:        jl= j -jk*stepm;
                   5079:        ju= j -(jk+1)*stepm;
                   5080:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5081:          if(jl==0){
                   5082:            dh[mi][i]=jk;
                   5083:            bh[mi][i]=0;
                   5084:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5085:                  * to avoid the price of an extra matrix product in likelihood */
                   5086:            dh[mi][i]=jk+1;
                   5087:            bh[mi][i]=ju;
                   5088:          }
                   5089:        }else{
                   5090:          if(jl <= -ju){
                   5091:            dh[mi][i]=jk;
                   5092:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5093:                                 * is higher than the multiple of stepm and negative otherwise.
                   5094:                                 */
                   5095:          }
                   5096:          else{
                   5097:            dh[mi][i]=jk+1;
                   5098:            bh[mi][i]=ju;
                   5099:          }
                   5100:          if(dh[mi][i]==0){
                   5101:            dh[mi][i]=1; /* At least one step */
                   5102:            bh[mi][i]=ju; /* At least one step */
                   5103:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5104:          }
                   5105:        } /* end if mle */
1.126     brouard  5106:       }
                   5107:     } /* end wave */
                   5108:   }
                   5109:   jmean=sum/k;
                   5110:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5111:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5112: }
1.126     brouard  5113: 
                   5114: /*********** Tricode ****************************/
1.220     brouard  5115:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5116:  {
                   5117:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5118:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5119:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5120:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5121:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5122:     */
1.130     brouard  5123: 
1.242     brouard  5124:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5125:    int modmaxcovj=0; /* Modality max of covariates j */
                   5126:    int cptcode=0; /* Modality max of covariates j */
                   5127:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5128: 
                   5129: 
1.242     brouard  5130:    /* cptcoveff=0;  */
                   5131:    /* *cptcov=0; */
1.126     brouard  5132:  
1.242     brouard  5133:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5134: 
1.242     brouard  5135:    /* Loop on covariates without age and products and no quantitative variable */
                   5136:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5137:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5138:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5139:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5140:        switch(Fixed[k]) {
                   5141:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5142:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5143:           ij=(int)(covar[Tvar[k]][i]);
                   5144:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5145:            * If product of Vn*Vm, still boolean *:
                   5146:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5147:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5148:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5149:              modality of the nth covariate of individual i. */
                   5150:           if (ij > modmaxcovj)
                   5151:             modmaxcovj=ij; 
                   5152:           else if (ij < modmincovj) 
                   5153:             modmincovj=ij; 
                   5154:           if ((ij < -1) && (ij > NCOVMAX)){
                   5155:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5156:             exit(1);
                   5157:           }else
                   5158:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5159:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5160:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5161:           /* getting the maximum value of the modality of the covariate
                   5162:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5163:              female ies 1, then modmaxcovj=1.
                   5164:           */
                   5165:         } /* end for loop on individuals i */
                   5166:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5167:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5168:         cptcode=modmaxcovj;
                   5169:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5170:         /*for (i=0; i<=cptcode; i++) {*/
                   5171:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5172:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5173:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5174:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5175:             if( j != -1){
                   5176:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5177:                                  covariate for which somebody answered excluding 
                   5178:                                  undefined. Usually 2: 0 and 1. */
                   5179:             }
                   5180:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5181:                                     covariate for which somebody answered including 
                   5182:                                     undefined. Usually 3: -1, 0 and 1. */
                   5183:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5184:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5185:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5186:                        
1.242     brouard  5187:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5188:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5189:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5190:         /* modmincovj=3; modmaxcovj = 7; */
                   5191:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5192:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5193:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5194:         /* nbcode[Tvar[j]][ij]=k; */
                   5195:         /* nbcode[Tvar[j]][1]=0; */
                   5196:         /* nbcode[Tvar[j]][2]=1; */
                   5197:         /* nbcode[Tvar[j]][3]=2; */
                   5198:         /* To be continued (not working yet). */
                   5199:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5200:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5201:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5202:             break;
                   5203:           }
                   5204:           ij++;
                   5205:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5206:           cptcode = ij; /* New max modality for covar j */
                   5207:         } /* end of loop on modality i=-1 to 1 or more */
                   5208:         break;
                   5209:        case 1: /* Testing on varying covariate, could be simple and
                   5210:                * should look at waves or product of fixed *
                   5211:                * varying. No time to test -1, assuming 0 and 1 only */
                   5212:         ij=0;
                   5213:         for(i=0; i<=1;i++){
                   5214:           nbcode[Tvar[k]][++ij]=i;
                   5215:         }
                   5216:         break;
                   5217:        default:
                   5218:         break;
                   5219:        } /* end switch */
                   5220:      } /* end dummy test */
                   5221:     
                   5222:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5223:      /*        /\*recode from 0 *\/ */
                   5224:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5225:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5226:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5227:      /*        } */
                   5228:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5229:      /*        if (ij > ncodemax[j]) { */
                   5230:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5231:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5232:      /*          break; */
                   5233:      /*        } */
                   5234:      /*   }  /\* end of loop on modality k *\/ */
                   5235:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5236:   
                   5237:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5238:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5239:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5240:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5241:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5242:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5243:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5244:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5245:   
                   5246:    ij=0;
                   5247:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5248:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5249:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5250:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5251:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5252:        /* If product not in single variable we don't print results */
                   5253:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5254:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5255:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5256:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5257:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5258:        if(Fixed[k]!=0)
                   5259:         anyvaryingduminmodel=1;
                   5260:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5261:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5262:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5263:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5264:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5265:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5266:      } 
                   5267:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5268:    /* ij--; */
                   5269:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5270:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5271:                * because they can be excluded from the model and real
                   5272:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5273:    for(j=ij+1; j<= cptcovt; j++){
                   5274:      Tvaraff[j]=0;
                   5275:      Tmodelind[j]=0;
                   5276:    }
                   5277:    for(j=ntveff+1; j<= cptcovt; j++){
                   5278:      TmodelInvind[j]=0;
                   5279:    }
                   5280:    /* To be sorted */
                   5281:    ;
                   5282:  }
1.126     brouard  5283: 
1.145     brouard  5284: 
1.126     brouard  5285: /*********** Health Expectancies ****************/
                   5286: 
1.235     brouard  5287:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5288: 
                   5289: {
                   5290:   /* Health expectancies, no variances */
1.164     brouard  5291:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5292:   int nhstepma, nstepma; /* Decreasing with age */
                   5293:   double age, agelim, hf;
                   5294:   double ***p3mat;
                   5295:   double eip;
                   5296: 
1.238     brouard  5297:   /* pstamp(ficreseij); */
1.126     brouard  5298:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5299:   fprintf(ficreseij,"# Age");
                   5300:   for(i=1; i<=nlstate;i++){
                   5301:     for(j=1; j<=nlstate;j++){
                   5302:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5303:     }
                   5304:     fprintf(ficreseij," e%1d. ",i);
                   5305:   }
                   5306:   fprintf(ficreseij,"\n");
                   5307: 
                   5308:   
                   5309:   if(estepm < stepm){
                   5310:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5311:   }
                   5312:   else  hstepm=estepm;   
                   5313:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5314:    * This is mainly to measure the difference between two models: for example
                   5315:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5316:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5317:    * progression in between and thus overestimating or underestimating according
                   5318:    * to the curvature of the survival function. If, for the same date, we 
                   5319:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5320:    * to compare the new estimate of Life expectancy with the same linear 
                   5321:    * hypothesis. A more precise result, taking into account a more precise
                   5322:    * curvature will be obtained if estepm is as small as stepm. */
                   5323: 
                   5324:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5325:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5326:      nhstepm is the number of hstepm from age to agelim 
                   5327:      nstepm is the number of stepm from age to agelin. 
                   5328:      Look at hpijx to understand the reason of that which relies in memory size
                   5329:      and note for a fixed period like estepm months */
                   5330:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5331:      survival function given by stepm (the optimization length). Unfortunately it
                   5332:      means that if the survival funtion is printed only each two years of age and if
                   5333:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5334:      results. So we changed our mind and took the option of the best precision.
                   5335:   */
                   5336:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5337: 
                   5338:   agelim=AGESUP;
                   5339:   /* If stepm=6 months */
                   5340:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5341:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5342:     
                   5343: /* nhstepm age range expressed in number of stepm */
                   5344:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5345:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5346:   /* if (stepm >= YEARM) hstepm=1;*/
                   5347:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5348:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5349: 
                   5350:   for (age=bage; age<=fage; age ++){ 
                   5351:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5352:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5353:     /* if (stepm >= YEARM) hstepm=1;*/
                   5354:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5355: 
                   5356:     /* If stepm=6 months */
                   5357:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5358:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5359:     
1.235     brouard  5360:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5361:     
                   5362:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5363:     
                   5364:     printf("%d|",(int)age);fflush(stdout);
                   5365:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5366:     
                   5367:     /* Computing expectancies */
                   5368:     for(i=1; i<=nlstate;i++)
                   5369:       for(j=1; j<=nlstate;j++)
                   5370:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5371:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5372:          
                   5373:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5374: 
                   5375:        }
                   5376: 
                   5377:     fprintf(ficreseij,"%3.0f",age );
                   5378:     for(i=1; i<=nlstate;i++){
                   5379:       eip=0;
                   5380:       for(j=1; j<=nlstate;j++){
                   5381:        eip +=eij[i][j][(int)age];
                   5382:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5383:       }
                   5384:       fprintf(ficreseij,"%9.4f", eip );
                   5385:     }
                   5386:     fprintf(ficreseij,"\n");
                   5387:     
                   5388:   }
                   5389:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5390:   printf("\n");
                   5391:   fprintf(ficlog,"\n");
                   5392:   
                   5393: }
                   5394: 
1.235     brouard  5395:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5396: 
                   5397: {
                   5398:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5399:      to initial status i, ei. .
1.126     brouard  5400:   */
                   5401:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5402:   int nhstepma, nstepma; /* Decreasing with age */
                   5403:   double age, agelim, hf;
                   5404:   double ***p3matp, ***p3matm, ***varhe;
                   5405:   double **dnewm,**doldm;
                   5406:   double *xp, *xm;
                   5407:   double **gp, **gm;
                   5408:   double ***gradg, ***trgradg;
                   5409:   int theta;
                   5410: 
                   5411:   double eip, vip;
                   5412: 
                   5413:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5414:   xp=vector(1,npar);
                   5415:   xm=vector(1,npar);
                   5416:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5417:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5418:   
                   5419:   pstamp(ficresstdeij);
                   5420:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5421:   fprintf(ficresstdeij,"# Age");
                   5422:   for(i=1; i<=nlstate;i++){
                   5423:     for(j=1; j<=nlstate;j++)
                   5424:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5425:     fprintf(ficresstdeij," e%1d. ",i);
                   5426:   }
                   5427:   fprintf(ficresstdeij,"\n");
                   5428: 
                   5429:   pstamp(ficrescveij);
                   5430:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5431:   fprintf(ficrescveij,"# Age");
                   5432:   for(i=1; i<=nlstate;i++)
                   5433:     for(j=1; j<=nlstate;j++){
                   5434:       cptj= (j-1)*nlstate+i;
                   5435:       for(i2=1; i2<=nlstate;i2++)
                   5436:        for(j2=1; j2<=nlstate;j2++){
                   5437:          cptj2= (j2-1)*nlstate+i2;
                   5438:          if(cptj2 <= cptj)
                   5439:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5440:        }
                   5441:     }
                   5442:   fprintf(ficrescveij,"\n");
                   5443:   
                   5444:   if(estepm < stepm){
                   5445:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5446:   }
                   5447:   else  hstepm=estepm;   
                   5448:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5449:    * This is mainly to measure the difference between two models: for example
                   5450:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5451:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5452:    * progression in between and thus overestimating or underestimating according
                   5453:    * to the curvature of the survival function. If, for the same date, we 
                   5454:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5455:    * to compare the new estimate of Life expectancy with the same linear 
                   5456:    * hypothesis. A more precise result, taking into account a more precise
                   5457:    * curvature will be obtained if estepm is as small as stepm. */
                   5458: 
                   5459:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5460:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5461:      nhstepm is the number of hstepm from age to agelim 
                   5462:      nstepm is the number of stepm from age to agelin. 
                   5463:      Look at hpijx to understand the reason of that which relies in memory size
                   5464:      and note for a fixed period like estepm months */
                   5465:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5466:      survival function given by stepm (the optimization length). Unfortunately it
                   5467:      means that if the survival funtion is printed only each two years of age and if
                   5468:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5469:      results. So we changed our mind and took the option of the best precision.
                   5470:   */
                   5471:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5472: 
                   5473:   /* If stepm=6 months */
                   5474:   /* nhstepm age range expressed in number of stepm */
                   5475:   agelim=AGESUP;
                   5476:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5477:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5478:   /* if (stepm >= YEARM) hstepm=1;*/
                   5479:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5480:   
                   5481:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5482:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5483:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5484:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5485:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5486:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5487: 
                   5488:   for (age=bage; age<=fage; age ++){ 
                   5489:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5490:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5491:     /* if (stepm >= YEARM) hstepm=1;*/
                   5492:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5493:                
1.126     brouard  5494:     /* If stepm=6 months */
                   5495:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5496:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5497:     
                   5498:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5499:                
1.126     brouard  5500:     /* Computing  Variances of health expectancies */
                   5501:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5502:        decrease memory allocation */
                   5503:     for(theta=1; theta <=npar; theta++){
                   5504:       for(i=1; i<=npar; i++){ 
1.222     brouard  5505:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5506:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5507:       }
1.235     brouard  5508:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5509:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5510:                        
1.126     brouard  5511:       for(j=1; j<= nlstate; j++){
1.222     brouard  5512:        for(i=1; i<=nlstate; i++){
                   5513:          for(h=0; h<=nhstepm-1; h++){
                   5514:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5515:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5516:          }
                   5517:        }
1.126     brouard  5518:       }
1.218     brouard  5519:                        
1.126     brouard  5520:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5521:        for(h=0; h<=nhstepm-1; h++){
                   5522:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5523:        }
1.126     brouard  5524:     }/* End theta */
                   5525:     
                   5526:     
                   5527:     for(h=0; h<=nhstepm-1; h++)
                   5528:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5529:        for(theta=1; theta <=npar; theta++)
                   5530:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5531:     
1.218     brouard  5532:                
1.222     brouard  5533:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5534:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5535:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5536:                
1.222     brouard  5537:     printf("%d|",(int)age);fflush(stdout);
                   5538:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5539:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5540:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5541:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5542:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5543:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5544:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5545:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5546:       }
                   5547:     }
1.218     brouard  5548:                
1.126     brouard  5549:     /* Computing expectancies */
1.235     brouard  5550:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5551:     for(i=1; i<=nlstate;i++)
                   5552:       for(j=1; j<=nlstate;j++)
1.222     brouard  5553:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5554:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5555:                                        
1.222     brouard  5556:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5557:                                        
1.222     brouard  5558:        }
1.218     brouard  5559:                
1.126     brouard  5560:     fprintf(ficresstdeij,"%3.0f",age );
                   5561:     for(i=1; i<=nlstate;i++){
                   5562:       eip=0.;
                   5563:       vip=0.;
                   5564:       for(j=1; j<=nlstate;j++){
1.222     brouard  5565:        eip += eij[i][j][(int)age];
                   5566:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5567:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5568:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5569:       }
                   5570:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5571:     }
                   5572:     fprintf(ficresstdeij,"\n");
1.218     brouard  5573:                
1.126     brouard  5574:     fprintf(ficrescveij,"%3.0f",age );
                   5575:     for(i=1; i<=nlstate;i++)
                   5576:       for(j=1; j<=nlstate;j++){
1.222     brouard  5577:        cptj= (j-1)*nlstate+i;
                   5578:        for(i2=1; i2<=nlstate;i2++)
                   5579:          for(j2=1; j2<=nlstate;j2++){
                   5580:            cptj2= (j2-1)*nlstate+i2;
                   5581:            if(cptj2 <= cptj)
                   5582:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5583:          }
1.126     brouard  5584:       }
                   5585:     fprintf(ficrescveij,"\n");
1.218     brouard  5586:                
1.126     brouard  5587:   }
                   5588:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5589:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5590:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5591:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5592:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5593:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5594:   printf("\n");
                   5595:   fprintf(ficlog,"\n");
1.218     brouard  5596:        
1.126     brouard  5597:   free_vector(xm,1,npar);
                   5598:   free_vector(xp,1,npar);
                   5599:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5600:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5601:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5602: }
1.218     brouard  5603:  
1.126     brouard  5604: /************ Variance ******************/
1.235     brouard  5605:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5606:  {
                   5607:    /* Variance of health expectancies */
                   5608:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5609:    /* double **newm;*/
                   5610:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5611:   
                   5612:    /* int movingaverage(); */
                   5613:    double **dnewm,**doldm;
                   5614:    double **dnewmp,**doldmp;
                   5615:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5616:    int k;
                   5617:    double *xp;
                   5618:    double **gp, **gm;  /* for var eij */
                   5619:    double ***gradg, ***trgradg; /*for var eij */
                   5620:    double **gradgp, **trgradgp; /* for var p point j */
                   5621:    double *gpp, *gmp; /* for var p point j */
                   5622:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5623:    double ***p3mat;
                   5624:    double age,agelim, hf;
                   5625:    /* double ***mobaverage; */
                   5626:    int theta;
                   5627:    char digit[4];
                   5628:    char digitp[25];
                   5629: 
                   5630:    char fileresprobmorprev[FILENAMELENGTH];
                   5631: 
                   5632:    if(popbased==1){
                   5633:      if(mobilav!=0)
                   5634:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5635:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5636:    }
                   5637:    else 
                   5638:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5639: 
1.218     brouard  5640:    /* if (mobilav!=0) { */
                   5641:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5642:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5643:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5644:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5645:    /*   } */
                   5646:    /* } */
                   5647: 
                   5648:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5649:    sprintf(digit,"%-d",ij);
                   5650:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5651:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5652:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5653:    strcat(fileresprobmorprev,fileresu);
                   5654:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5655:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5656:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5657:    }
                   5658:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5659:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5660:    pstamp(ficresprobmorprev);
                   5661:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5662:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5663:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5664:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5665:    }
                   5666:    for(j=1;j<=cptcoveff;j++) 
                   5667:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5668:    fprintf(ficresprobmorprev,"\n");
                   5669: 
1.218     brouard  5670:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5671:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5672:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5673:      for(i=1; i<=nlstate;i++)
                   5674:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5675:    }  
                   5676:    fprintf(ficresprobmorprev,"\n");
                   5677:   
                   5678:    fprintf(ficgp,"\n# Routine varevsij");
                   5679:    fprintf(ficgp,"\nunset title \n");
                   5680:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5681:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5682:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5683:    /*   } */
                   5684:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5685:    pstamp(ficresvij);
                   5686:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5687:    if(popbased==1)
                   5688:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5689:    else
                   5690:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5691:    fprintf(ficresvij,"# Age");
                   5692:    for(i=1; i<=nlstate;i++)
                   5693:      for(j=1; j<=nlstate;j++)
                   5694:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5695:    fprintf(ficresvij,"\n");
                   5696: 
                   5697:    xp=vector(1,npar);
                   5698:    dnewm=matrix(1,nlstate,1,npar);
                   5699:    doldm=matrix(1,nlstate,1,nlstate);
                   5700:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5701:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5702: 
                   5703:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5704:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5705:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5706:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5707:   
1.218     brouard  5708:    if(estepm < stepm){
                   5709:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5710:    }
                   5711:    else  hstepm=estepm;   
                   5712:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5713:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5714:       nhstepm is the number of hstepm from age to agelim 
                   5715:       nstepm is the number of stepm from age to agelim. 
                   5716:       Look at function hpijx to understand why because of memory size limitations, 
                   5717:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5718:       survival function given by stepm (the optimization length). Unfortunately it
                   5719:       means that if the survival funtion is printed every two years of age and if
                   5720:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5721:       results. So we changed our mind and took the option of the best precision.
                   5722:    */
                   5723:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5724:    agelim = AGESUP;
                   5725:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5726:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5727:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5728:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5729:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5730:      gp=matrix(0,nhstepm,1,nlstate);
                   5731:      gm=matrix(0,nhstepm,1,nlstate);
                   5732:                
                   5733:                
                   5734:      for(theta=1; theta <=npar; theta++){
                   5735:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5736:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5737:        }
                   5738:                        
1.242     brouard  5739:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5740:                        
                   5741:        if (popbased==1) {
                   5742:         if(mobilav ==0){
                   5743:           for(i=1; i<=nlstate;i++)
                   5744:             prlim[i][i]=probs[(int)age][i][ij];
                   5745:         }else{ /* mobilav */ 
                   5746:           for(i=1; i<=nlstate;i++)
                   5747:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5748:         }
                   5749:        }
                   5750:                        
1.235     brouard  5751:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5752:        for(j=1; j<= nlstate; j++){
                   5753:         for(h=0; h<=nhstepm; h++){
                   5754:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5755:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5756:         }
                   5757:        }
                   5758:        /* Next for computing probability of death (h=1 means
                   5759:          computed over hstepm matrices product = hstepm*stepm months) 
                   5760:          as a weighted average of prlim.
                   5761:        */
                   5762:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5763:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5764:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5765:        }    
                   5766:        /* end probability of death */
                   5767:                        
                   5768:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5769:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5770:                        
1.242     brouard  5771:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5772:                        
                   5773:        if (popbased==1) {
                   5774:         if(mobilav ==0){
                   5775:           for(i=1; i<=nlstate;i++)
                   5776:             prlim[i][i]=probs[(int)age][i][ij];
                   5777:         }else{ /* mobilav */ 
                   5778:           for(i=1; i<=nlstate;i++)
                   5779:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5780:         }
                   5781:        }
                   5782:                        
1.235     brouard  5783:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5784:                        
                   5785:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5786:         for(h=0; h<=nhstepm; h++){
                   5787:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5788:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5789:         }
                   5790:        }
                   5791:        /* This for computing probability of death (h=1 means
                   5792:          computed over hstepm matrices product = hstepm*stepm months) 
                   5793:          as a weighted average of prlim.
                   5794:        */
                   5795:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5796:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5797:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5798:        }    
                   5799:        /* end probability of death */
                   5800:                        
                   5801:        for(j=1; j<= nlstate; j++) /* vareij */
                   5802:         for(h=0; h<=nhstepm; h++){
                   5803:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5804:         }
                   5805:                        
                   5806:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5807:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5808:        }
                   5809:                        
                   5810:      } /* End theta */
                   5811:                
                   5812:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5813:                
                   5814:      for(h=0; h<=nhstepm; h++) /* veij */
                   5815:        for(j=1; j<=nlstate;j++)
                   5816:         for(theta=1; theta <=npar; theta++)
                   5817:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5818:                
                   5819:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5820:        for(theta=1; theta <=npar; theta++)
                   5821:         trgradgp[j][theta]=gradgp[theta][j];
                   5822:                
                   5823:                
                   5824:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5825:      for(i=1;i<=nlstate;i++)
                   5826:        for(j=1;j<=nlstate;j++)
                   5827:         vareij[i][j][(int)age] =0.;
                   5828:                
                   5829:      for(h=0;h<=nhstepm;h++){
                   5830:        for(k=0;k<=nhstepm;k++){
                   5831:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5832:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5833:         for(i=1;i<=nlstate;i++)
                   5834:           for(j=1;j<=nlstate;j++)
                   5835:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5836:        }
                   5837:      }
                   5838:                
                   5839:      /* pptj */
                   5840:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5841:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5842:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5843:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5844:         varppt[j][i]=doldmp[j][i];
                   5845:      /* end ppptj */
                   5846:      /*  x centered again */
                   5847:                
1.242     brouard  5848:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5849:                
                   5850:      if (popbased==1) {
                   5851:        if(mobilav ==0){
                   5852:         for(i=1; i<=nlstate;i++)
                   5853:           prlim[i][i]=probs[(int)age][i][ij];
                   5854:        }else{ /* mobilav */ 
                   5855:         for(i=1; i<=nlstate;i++)
                   5856:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5857:        }
                   5858:      }
                   5859:                
                   5860:      /* This for computing probability of death (h=1 means
                   5861:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5862:        as a weighted average of prlim.
                   5863:      */
1.235     brouard  5864:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5865:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5866:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5867:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5868:      }    
                   5869:      /* end probability of death */
                   5870:                
                   5871:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5872:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5873:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5874:        for(i=1; i<=nlstate;i++){
                   5875:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5876:        }
                   5877:      } 
                   5878:      fprintf(ficresprobmorprev,"\n");
                   5879:                
                   5880:      fprintf(ficresvij,"%.0f ",age );
                   5881:      for(i=1; i<=nlstate;i++)
                   5882:        for(j=1; j<=nlstate;j++){
                   5883:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5884:        }
                   5885:      fprintf(ficresvij,"\n");
                   5886:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5887:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5888:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5889:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5890:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5891:    } /* End age */
                   5892:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5893:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5894:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5895:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5896:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5897:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5898:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5899:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5900:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5901:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5902:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5903:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5904:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5905:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5906:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5907:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5908:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5909:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5910:     */
1.218     brouard  5911:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5912:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5913: 
1.218     brouard  5914:    free_vector(xp,1,npar);
                   5915:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5916:    free_matrix(dnewm,1,nlstate,1,npar);
                   5917:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5918:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5919:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5920:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5921:    fclose(ficresprobmorprev);
                   5922:    fflush(ficgp);
                   5923:    fflush(fichtm); 
                   5924:  }  /* end varevsij */
1.126     brouard  5925: 
                   5926: /************ Variance of prevlim ******************/
1.235     brouard  5927:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5928: {
1.205     brouard  5929:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5930:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5931: 
1.126     brouard  5932:   double **dnewm,**doldm;
                   5933:   int i, j, nhstepm, hstepm;
                   5934:   double *xp;
                   5935:   double *gp, *gm;
                   5936:   double **gradg, **trgradg;
1.208     brouard  5937:   double **mgm, **mgp;
1.126     brouard  5938:   double age,agelim;
                   5939:   int theta;
                   5940:   
                   5941:   pstamp(ficresvpl);
                   5942:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5943:   fprintf(ficresvpl,"# Age ");
                   5944:   if(nresult >=1)
                   5945:     fprintf(ficresvpl," Result# ");
1.126     brouard  5946:   for(i=1; i<=nlstate;i++)
                   5947:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5948:   fprintf(ficresvpl,"\n");
                   5949: 
                   5950:   xp=vector(1,npar);
                   5951:   dnewm=matrix(1,nlstate,1,npar);
                   5952:   doldm=matrix(1,nlstate,1,nlstate);
                   5953:   
                   5954:   hstepm=1*YEARM; /* Every year of age */
                   5955:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5956:   agelim = AGESUP;
                   5957:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5958:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5959:     if (stepm >= YEARM) hstepm=1;
                   5960:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5961:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5962:     mgp=matrix(1,npar,1,nlstate);
                   5963:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5964:     gp=vector(1,nlstate);
                   5965:     gm=vector(1,nlstate);
                   5966: 
                   5967:     for(theta=1; theta <=npar; theta++){
                   5968:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5969:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5970:       }
1.209     brouard  5971:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5972:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5973:       else
1.235     brouard  5974:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5975:       for(i=1;i<=nlstate;i++){
1.126     brouard  5976:        gp[i] = prlim[i][i];
1.208     brouard  5977:        mgp[theta][i] = prlim[i][i];
                   5978:       }
1.126     brouard  5979:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5980:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5981:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5982:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5983:       else
1.235     brouard  5984:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5985:       for(i=1;i<=nlstate;i++){
1.126     brouard  5986:        gm[i] = prlim[i][i];
1.208     brouard  5987:        mgm[theta][i] = prlim[i][i];
                   5988:       }
1.126     brouard  5989:       for(i=1;i<=nlstate;i++)
                   5990:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5991:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5992:     } /* End theta */
                   5993: 
                   5994:     trgradg =matrix(1,nlstate,1,npar);
                   5995: 
                   5996:     for(j=1; j<=nlstate;j++)
                   5997:       for(theta=1; theta <=npar; theta++)
                   5998:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  5999:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6000:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6001:     /*   for(j=1; j<=nlstate;j++){ */
                   6002:     /*         printf(" %d ",j); */
                   6003:     /*         for(theta=1; theta <=npar; theta++) */
                   6004:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6005:     /*         printf("\n "); */
                   6006:     /*   } */
                   6007:     /* } */
                   6008:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6009:     /*   printf("\n gradg %d ",(int)age); */
                   6010:     /*   for(j=1; j<=nlstate;j++){ */
                   6011:     /*         printf("%d ",j); */
                   6012:     /*         for(theta=1; theta <=npar; theta++) */
                   6013:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6014:     /*         printf("\n "); */
                   6015:     /*   } */
                   6016:     /* } */
1.126     brouard  6017: 
                   6018:     for(i=1;i<=nlstate;i++)
                   6019:       varpl[i][(int)age] =0.;
1.209     brouard  6020:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  6021:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6022:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   6023:     }else{
1.126     brouard  6024:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6025:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6026:     }
1.126     brouard  6027:     for(i=1;i<=nlstate;i++)
                   6028:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6029: 
                   6030:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6031:     if(nresult >=1)
                   6032:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6033:     for(i=1; i<=nlstate;i++)
                   6034:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6035:     fprintf(ficresvpl,"\n");
                   6036:     free_vector(gp,1,nlstate);
                   6037:     free_vector(gm,1,nlstate);
1.208     brouard  6038:     free_matrix(mgm,1,npar,1,nlstate);
                   6039:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6040:     free_matrix(gradg,1,npar,1,nlstate);
                   6041:     free_matrix(trgradg,1,nlstate,1,npar);
                   6042:   } /* End age */
                   6043: 
                   6044:   free_vector(xp,1,npar);
                   6045:   free_matrix(doldm,1,nlstate,1,npar);
                   6046:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6047: 
                   6048: }
                   6049: 
                   6050: /************ Variance of one-step probabilities  ******************/
                   6051: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6052:  {
                   6053:    int i, j=0,  k1, l1, tj;
                   6054:    int k2, l2, j1,  z1;
                   6055:    int k=0, l;
                   6056:    int first=1, first1, first2;
                   6057:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6058:    double **dnewm,**doldm;
                   6059:    double *xp;
                   6060:    double *gp, *gm;
                   6061:    double **gradg, **trgradg;
                   6062:    double **mu;
                   6063:    double age, cov[NCOVMAX+1];
                   6064:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6065:    int theta;
                   6066:    char fileresprob[FILENAMELENGTH];
                   6067:    char fileresprobcov[FILENAMELENGTH];
                   6068:    char fileresprobcor[FILENAMELENGTH];
                   6069:    double ***varpij;
                   6070: 
                   6071:    strcpy(fileresprob,"PROB_"); 
                   6072:    strcat(fileresprob,fileres);
                   6073:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6074:      printf("Problem with resultfile: %s\n", fileresprob);
                   6075:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6076:    }
                   6077:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6078:    strcat(fileresprobcov,fileresu);
                   6079:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6080:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6081:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6082:    }
                   6083:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6084:    strcat(fileresprobcor,fileresu);
                   6085:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6086:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6087:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6088:    }
                   6089:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6090:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6091:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6092:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6093:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6094:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6095:    pstamp(ficresprob);
                   6096:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6097:    fprintf(ficresprob,"# Age");
                   6098:    pstamp(ficresprobcov);
                   6099:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6100:    fprintf(ficresprobcov,"# Age");
                   6101:    pstamp(ficresprobcor);
                   6102:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6103:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6104: 
                   6105: 
1.222     brouard  6106:    for(i=1; i<=nlstate;i++)
                   6107:      for(j=1; j<=(nlstate+ndeath);j++){
                   6108:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6109:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6110:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6111:      }  
                   6112:    /* fprintf(ficresprob,"\n");
                   6113:       fprintf(ficresprobcov,"\n");
                   6114:       fprintf(ficresprobcor,"\n");
                   6115:    */
                   6116:    xp=vector(1,npar);
                   6117:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6118:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6119:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6120:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6121:    first=1;
                   6122:    fprintf(ficgp,"\n# Routine varprob");
                   6123:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6124:    fprintf(fichtm,"\n");
                   6125: 
                   6126:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6127:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6128:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6129: and drawn. It helps understanding how is the covariance between two incidences.\
                   6130:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6131:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6132: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6133: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6134: standard deviations wide on each axis. <br>\
                   6135:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6136:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6137: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6138: 
1.222     brouard  6139:    cov[1]=1;
                   6140:    /* tj=cptcoveff; */
1.225     brouard  6141:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6142:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6143:    j1=0;
1.224     brouard  6144:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6145:      if  (cptcovn>0) {
                   6146:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6147:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6148:        fprintf(ficresprob, "**********\n#\n");
                   6149:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6150:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6151:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6152:                        
1.222     brouard  6153:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6154:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6155:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6156:                        
                   6157:                        
1.222     brouard  6158:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6159:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6160:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6161:                        
1.222     brouard  6162:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6163:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6164:        fprintf(ficresprobcor, "**********\n#");    
                   6165:        if(invalidvarcomb[j1]){
                   6166:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6167:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6168:         continue;
                   6169:        }
                   6170:      }
                   6171:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6172:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6173:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6174:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6175:      for (age=bage; age<=fage; age ++){ 
                   6176:        cov[2]=age;
                   6177:        if(nagesqr==1)
                   6178:         cov[3]= age*age;
                   6179:        for (k=1; k<=cptcovn;k++) {
                   6180:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6181:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6182:                                                                    * 1  1 1 1 1
                   6183:                                                                    * 2  2 1 1 1
                   6184:                                                                    * 3  1 2 1 1
                   6185:                                                                    */
                   6186:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6187:        }
                   6188:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6189:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6190:        for (k=1; k<=cptcovprod;k++)
                   6191:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6192:                        
                   6193:                        
1.222     brouard  6194:        for(theta=1; theta <=npar; theta++){
                   6195:         for(i=1; i<=npar; i++)
                   6196:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6197:                                
1.222     brouard  6198:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6199:                                
1.222     brouard  6200:         k=0;
                   6201:         for(i=1; i<= (nlstate); i++){
                   6202:           for(j=1; j<=(nlstate+ndeath);j++){
                   6203:             k=k+1;
                   6204:             gp[k]=pmmij[i][j];
                   6205:           }
                   6206:         }
1.220     brouard  6207:                                
1.222     brouard  6208:         for(i=1; i<=npar; i++)
                   6209:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6210:                                
1.222     brouard  6211:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6212:         k=0;
                   6213:         for(i=1; i<=(nlstate); i++){
                   6214:           for(j=1; j<=(nlstate+ndeath);j++){
                   6215:             k=k+1;
                   6216:             gm[k]=pmmij[i][j];
                   6217:           }
                   6218:         }
1.220     brouard  6219:                                
1.222     brouard  6220:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6221:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6222:        }
1.126     brouard  6223: 
1.222     brouard  6224:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6225:         for(theta=1; theta <=npar; theta++)
                   6226:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6227:                        
1.222     brouard  6228:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6229:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6230:                        
1.222     brouard  6231:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6232:                        
1.222     brouard  6233:        k=0;
                   6234:        for(i=1; i<=(nlstate); i++){
                   6235:         for(j=1; j<=(nlstate+ndeath);j++){
                   6236:           k=k+1;
                   6237:           mu[k][(int) age]=pmmij[i][j];
                   6238:         }
                   6239:        }
                   6240:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6241:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6242:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6243:                        
1.222     brouard  6244:        /*printf("\n%d ",(int)age);
                   6245:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6246:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6247:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6248:         }*/
1.220     brouard  6249:                        
1.222     brouard  6250:        fprintf(ficresprob,"\n%d ",(int)age);
                   6251:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6252:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6253:                        
1.222     brouard  6254:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6255:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6256:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6257:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6258:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6259:        }
                   6260:        i=0;
                   6261:        for (k=1; k<=(nlstate);k++){
                   6262:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6263:           i++;
                   6264:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6265:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6266:           for (j=1; j<=i;j++){
                   6267:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6268:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6269:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6270:           }
                   6271:         }
                   6272:        }/* end of loop for state */
                   6273:      } /* end of loop for age */
                   6274:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6275:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6276:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6277:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6278:     
                   6279:      /* Confidence intervalle of pij  */
                   6280:      /*
                   6281:        fprintf(ficgp,"\nunset parametric;unset label");
                   6282:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6283:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6284:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6285:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6286:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6287:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6288:      */
                   6289:                
                   6290:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6291:      first1=1;first2=2;
                   6292:      for (k2=1; k2<=(nlstate);k2++){
                   6293:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6294:         if(l2==k2) continue;
                   6295:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6296:         for (k1=1; k1<=(nlstate);k1++){
                   6297:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6298:             if(l1==k1) continue;
                   6299:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6300:             if(i<=j) continue;
                   6301:             for (age=bage; age<=fage; age ++){ 
                   6302:               if ((int)age %5==0){
                   6303:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6304:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6305:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6306:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6307:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6308:                 c12=cv12/sqrt(v1*v2);
                   6309:                 /* Computing eigen value of matrix of covariance */
                   6310:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6311:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6312:                 if ((lc2 <0) || (lc1 <0) ){
                   6313:                   if(first2==1){
                   6314:                     first1=0;
                   6315:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6316:                   }
                   6317:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6318:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6319:                   /* lc2=fabs(lc2); */
                   6320:                 }
1.220     brouard  6321:                                                                
1.222     brouard  6322:                 /* Eigen vectors */
                   6323:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6324:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6325:                 v21=(lc1-v1)/cv12*v11;
                   6326:                 v12=-v21;
                   6327:                 v22=v11;
                   6328:                 tnalp=v21/v11;
                   6329:                 if(first1==1){
                   6330:                   first1=0;
                   6331:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6332:                 }
                   6333:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6334:                 /*printf(fignu*/
                   6335:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6336:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6337:                 if(first==1){
                   6338:                   first=0;
                   6339:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6340:                   fprintf(ficgp,"\nset parametric;unset label");
                   6341:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6342:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6343:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6344:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6345: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6346:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6347:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6348:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6349:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6350:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6351:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6352:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6353:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6354:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6355:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6356:                 }else{
                   6357:                   first=0;
                   6358:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6359:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6360:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6361:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6362:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6363:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6364:                 }/* if first */
                   6365:               } /* age mod 5 */
                   6366:             } /* end loop age */
                   6367:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6368:             first=1;
                   6369:           } /*l12 */
                   6370:         } /* k12 */
                   6371:        } /*l1 */
                   6372:      }/* k1 */
                   6373:    }  /* loop on combination of covariates j1 */
                   6374:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6375:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6376:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6377:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6378:    free_vector(xp,1,npar);
                   6379:    fclose(ficresprob);
                   6380:    fclose(ficresprobcov);
                   6381:    fclose(ficresprobcor);
                   6382:    fflush(ficgp);
                   6383:    fflush(fichtmcov);
                   6384:  }
1.126     brouard  6385: 
                   6386: 
                   6387: /******************* Printing html file ***********/
1.201     brouard  6388: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6389:                  int lastpass, int stepm, int weightopt, char model[],\
                   6390:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6391:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6392:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6393:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6394:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6395: 
                   6396:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6397:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6398: </ul>");
1.237     brouard  6399:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6400: </ul>", model);
1.214     brouard  6401:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6402:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6403:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6404:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6405:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6406:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6407:    fprintf(fichtm,"\
                   6408:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6409:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6410:    fprintf(fichtm,"\
1.217     brouard  6411:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6412:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6413:    fprintf(fichtm,"\
1.126     brouard  6414:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6415:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6416:    fprintf(fichtm,"\
1.217     brouard  6417:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6418:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6419:    fprintf(fichtm,"\
1.211     brouard  6420:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6421:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6422:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6423:    if(prevfcast==1){
                   6424:      fprintf(fichtm,"\
                   6425:  - Prevalence projections by age and states:                           \
1.201     brouard  6426:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6427:    }
1.126     brouard  6428: 
1.222     brouard  6429:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6430: 
1.225     brouard  6431:    m=pow(2,cptcoveff);
1.222     brouard  6432:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6433: 
1.222     brouard  6434:    jj1=0;
1.237     brouard  6435: 
                   6436:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6437:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6438:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6439:        continue;
1.220     brouard  6440: 
1.222     brouard  6441:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6442:      jj1++;
                   6443:      if (cptcovn > 0) {
                   6444:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6445:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6446:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6447:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6448:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6449:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6450:        }
1.237     brouard  6451:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6452:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6453:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6454:       }
                   6455:        
1.230     brouard  6456:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6457:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6458:        if(invalidvarcomb[k1]){
                   6459:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6460:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6461:         continue;
                   6462:        }
                   6463:      }
                   6464:      /* aij, bij */
1.259     brouard  6465:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6466: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6467:      /* Pij */
1.241     brouard  6468:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6469: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6470:      /* Quasi-incidences */
                   6471:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6472:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6473:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6474: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6475: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6476:      /* Survival functions (period) in state j */
                   6477:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6478:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6479: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6480:      }
                   6481:      /* State specific survival functions (period) */
                   6482:      for(cpt=1; cpt<=nlstate;cpt++){
                   6483:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6484:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6485:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6486:      }
                   6487:      /* Period (stable) prevalence in each health state */
                   6488:      for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6489:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d some years earlier, knowing that we will be in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6490: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6491:      }
                   6492:      if(backcast==1){
                   6493:        /* Period (stable) back prevalence in each health state */
                   6494:        for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6495:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability to be in state %d at a younger age, knowing that we will be in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6496: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6497:        }
1.217     brouard  6498:      }
1.222     brouard  6499:      if(prevfcast==1){
                   6500:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6501:        for(cpt=1; cpt<=nlstate;cpt++){
1.258     brouard  6502:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6503: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6504:        }
                   6505:      }
1.220     brouard  6506:         
1.222     brouard  6507:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6508:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6509: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6510:      }
                   6511:      /* } /\* end i1 *\/ */
                   6512:    }/* End k1 */
                   6513:    fprintf(fichtm,"</ul>");
1.126     brouard  6514: 
1.222     brouard  6515:    fprintf(fichtm,"\
1.126     brouard  6516: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6517:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6518:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6519: But because parameters are usually highly correlated (a higher incidence of disability \
                   6520: and a higher incidence of recovery can give very close observed transition) it might \
                   6521: be very useful to look not only at linear confidence intervals estimated from the \
                   6522: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6523: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6524: covariance matrix of the one-step probabilities. \
                   6525: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6526: 
1.222     brouard  6527:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6528:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6529:    fprintf(fichtm,"\
1.126     brouard  6530:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6531:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6532: 
1.222     brouard  6533:    fprintf(fichtm,"\
1.126     brouard  6534:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6535:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6536:    fprintf(fichtm,"\
1.126     brouard  6537:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6538:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6539:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6540:    fprintf(fichtm,"\
1.126     brouard  6541:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6542:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6543:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6544:    fprintf(fichtm,"\
1.128     brouard  6545:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6546:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6547:    fprintf(fichtm,"\
1.128     brouard  6548:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6549:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6550:    fprintf(fichtm,"\
1.126     brouard  6551:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6552:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6553: 
                   6554: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6555: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6556: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6557: /*     <br>",fileres,fileres,fileres,fileres); */
                   6558: /*  else  */
                   6559: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6560:    fflush(fichtm);
                   6561:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6562: 
1.225     brouard  6563:    m=pow(2,cptcoveff);
1.222     brouard  6564:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6565: 
1.222     brouard  6566:    jj1=0;
1.237     brouard  6567: 
1.241     brouard  6568:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6569:    for(k1=1; k1<=m;k1++){
1.253     brouard  6570:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6571:        continue;
1.222     brouard  6572:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6573:      jj1++;
1.126     brouard  6574:      if (cptcovn > 0) {
                   6575:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6576:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6577:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6578:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6579:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6580:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6581:       }
                   6582: 
1.126     brouard  6583:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6584: 
1.222     brouard  6585:        if(invalidvarcomb[k1]){
                   6586:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6587:         continue;
                   6588:        }
1.126     brouard  6589:      }
                   6590:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6591:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6592: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6593: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6594:      }
                   6595:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6596: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6597: true period expectancies (those weighted with period prevalences are also\
                   6598:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6599:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6600: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6601:      /* } /\* end i1 *\/ */
                   6602:    }/* End k1 */
1.241     brouard  6603:   }/* End nres */
1.222     brouard  6604:    fprintf(fichtm,"</ul>");
                   6605:    fflush(fichtm);
1.126     brouard  6606: }
                   6607: 
                   6608: /******************* Gnuplot file **************/
1.223     brouard  6609: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6610: 
                   6611:   char dirfileres[132],optfileres[132];
1.223     brouard  6612:   char gplotcondition[132];
1.237     brouard  6613:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6614:   int lv=0, vlv=0, kl=0;
1.130     brouard  6615:   int ng=0;
1.201     brouard  6616:   int vpopbased;
1.223     brouard  6617:   int ioffset; /* variable offset for columns */
1.235     brouard  6618:   int nres=0; /* Index of resultline */
1.219     brouard  6619: 
1.126     brouard  6620: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6621: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6622: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6623: /*   } */
                   6624: 
                   6625:   /*#ifdef windows */
                   6626:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6627:   /*#endif */
1.225     brouard  6628:   m=pow(2,cptcoveff);
1.126     brouard  6629: 
1.202     brouard  6630:   /* Contribution to likelihood */
                   6631:   /* Plot the probability implied in the likelihood */
1.223     brouard  6632:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6633:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6634:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6635:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6636: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6637:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6638: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6639:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6640:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6641:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6642:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6643:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6644:   for (i=1; i<= nlstate ; i ++) {
                   6645:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6646:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6647:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6648:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6649:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6650:     }
                   6651:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6652:   }
                   6653:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6654:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6655:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6656:   fprintf(ficgp,"\nset out;unset log\n");
                   6657:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6658: 
1.126     brouard  6659:   strcpy(dirfileres,optionfilefiname);
                   6660:   strcpy(optfileres,"vpl");
1.223     brouard  6661:   /* 1eme*/
1.238     brouard  6662:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6663:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6664:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6665:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6666:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6667:          continue;
                   6668:        /* We are interested in selected combination by the resultline */
1.246     brouard  6669:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6670:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6671:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6672:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6673:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6674:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6675:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6676:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6677:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6678:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6679:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6680:        }
                   6681:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6682:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6683:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6684:        }       
1.246     brouard  6685:        /* printf("\n#\n"); */
1.238     brouard  6686:        fprintf(ficgp,"\n#\n");
                   6687:        if(invalidvarcomb[k1]){
1.260     brouard  6688:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  6689:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6690:          continue;
                   6691:        }
1.235     brouard  6692:       
1.241     brouard  6693:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6694:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.260     brouard  6695:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   6696:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   6697:       /* k1-1 error should be nres-1*/
1.238     brouard  6698:        for (i=1; i<= nlstate ; i ++) {
                   6699:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6700:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6701:        }
1.260     brouard  6702:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  6703:        for (i=1; i<= nlstate ; i ++) {
                   6704:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6705:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6706:        } 
1.260     brouard  6707:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  6708:        for (i=1; i<= nlstate ; i ++) {
                   6709:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6710:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6711:        }  
                   6712:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6713:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6714:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6715:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6716:          if(cptcoveff ==0){
1.245     brouard  6717:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6718:          }else{
                   6719:            kl=0;
                   6720:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6721:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6722:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6723:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6724:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6725:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6726:              kl++;
1.238     brouard  6727:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6728:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6729:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6730:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6731:              if(k==cptcoveff){
1.245     brouard  6732:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6733:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6734:              }else{
                   6735:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6736:                kl++;
                   6737:              }
                   6738:            } /* end covariate */
                   6739:          } /* end if no covariate */
                   6740:        } /* end if backcast */
                   6741:        fprintf(ficgp,"\nset out \n");
                   6742:       } /* nres */
1.201     brouard  6743:     } /* k1 */
                   6744:   } /* cpt */
1.235     brouard  6745: 
                   6746:   
1.126     brouard  6747:   /*2 eme*/
1.238     brouard  6748:   for (k1=1; k1<= m ; k1 ++){  
                   6749:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6750:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6751:        continue;
                   6752:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6753:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6754:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6755:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6756:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6757:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6758:        vlv= nbcode[Tvaraff[k]][lv];
                   6759:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6760:       }
1.237     brouard  6761:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6762:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6763:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6764:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6765:       }
1.211     brouard  6766:       fprintf(ficgp,"\n#\n");
1.223     brouard  6767:       if(invalidvarcomb[k1]){
                   6768:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6769:        continue;
                   6770:       }
1.219     brouard  6771:                        
1.241     brouard  6772:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6773:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6774:        if(vpopbased==0)
                   6775:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6776:        else
                   6777:          fprintf(ficgp,"\nreplot ");
                   6778:        for (i=1; i<= nlstate+1 ; i ++) {
                   6779:          k=2*i;
1.261   ! brouard  6780:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  6781:          for (j=1; j<= nlstate+1 ; j ++) {
                   6782:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6783:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6784:          }   
                   6785:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6786:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261   ! brouard  6787:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6788:          for (j=1; j<= nlstate+1 ; j ++) {
                   6789:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6790:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6791:          }   
                   6792:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261   ! brouard  6793:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6794:          for (j=1; j<= nlstate+1 ; j ++) {
                   6795:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6796:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6797:          }   
                   6798:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6799:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6800:        } /* state */
                   6801:       } /* vpopbased */
1.244     brouard  6802:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6803:     } /* end nres */
                   6804:   } /* k1 end 2 eme*/
                   6805:        
                   6806:        
                   6807:   /*3eme*/
                   6808:   for (k1=1; k1<= m ; k1 ++){
                   6809:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6810:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6811:        continue;
                   6812: 
                   6813:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261   ! brouard  6814:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.238     brouard  6815:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6816:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6817:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6818:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6819:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6820:          vlv= nbcode[Tvaraff[k]][lv];
                   6821:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6822:        }
                   6823:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6824:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6825:        }       
                   6826:        fprintf(ficgp,"\n#\n");
                   6827:        if(invalidvarcomb[k1]){
                   6828:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6829:          continue;
                   6830:        }
                   6831:                        
                   6832:        /*       k=2+nlstate*(2*cpt-2); */
                   6833:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6834:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6835:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261   ! brouard  6836: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  6837:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6838:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6839:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6840:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6841:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6842:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6843:                                
1.238     brouard  6844:        */
                   6845:        for (i=1; i< nlstate ; i ++) {
1.261   ! brouard  6846:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  6847:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6848:                                
1.238     brouard  6849:        } 
1.261   ! brouard  6850:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  6851:       }
                   6852:     } /* end nres */
                   6853:   } /* end kl 3eme */
1.126     brouard  6854:   
1.223     brouard  6855:   /* 4eme */
1.201     brouard  6856:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6857:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6858:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6859:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6860:        continue;
1.238     brouard  6861:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6862:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6863:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6864:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6865:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6866:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6867:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6868:          vlv= nbcode[Tvaraff[k]][lv];
                   6869:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6870:        }
                   6871:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6872:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6873:        }       
                   6874:        fprintf(ficgp,"\n#\n");
                   6875:        if(invalidvarcomb[k1]){
                   6876:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6877:          continue;
1.223     brouard  6878:        }
1.238     brouard  6879:       
1.241     brouard  6880:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6881:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6882: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6883:        k=3;
                   6884:        for (i=1; i<= nlstate ; i ++){
                   6885:          if(i==1){
                   6886:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6887:          }else{
                   6888:            fprintf(ficgp,", '' ");
                   6889:          }
                   6890:          l=(nlstate+ndeath)*(i-1)+1;
                   6891:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6892:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6893:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6894:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6895:        } /* nlstate */
                   6896:        fprintf(ficgp,"\nset out\n");
                   6897:       } /* end cpt state*/ 
                   6898:     } /* end nres */
                   6899:   } /* end covariate k1 */  
                   6900: 
1.220     brouard  6901: /* 5eme */
1.201     brouard  6902:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6903:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6904:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6905:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6906:        continue;
1.238     brouard  6907:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6908:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6909:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6910:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6911:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6912:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6913:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6914:          vlv= nbcode[Tvaraff[k]][lv];
                   6915:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6916:        }
                   6917:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6918:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6919:        }       
                   6920:        fprintf(ficgp,"\n#\n");
                   6921:        if(invalidvarcomb[k1]){
                   6922:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6923:          continue;
                   6924:        }
1.227     brouard  6925:       
1.241     brouard  6926:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6927:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6928: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6929:        k=3;
                   6930:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6931:          if(j==1)
                   6932:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6933:          else
                   6934:            fprintf(ficgp,", '' ");
                   6935:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6936:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6937:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6938:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6939:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6940:        } /* nlstate */
                   6941:        fprintf(ficgp,", '' ");
                   6942:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6943:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6944:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6945:          if(j < nlstate)
                   6946:            fprintf(ficgp,"$%d +",k+l);
                   6947:          else
                   6948:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6949:        }
                   6950:        fprintf(ficgp,"\nset out\n");
                   6951:       } /* end cpt state*/ 
                   6952:     } /* end covariate */  
                   6953:   } /* end nres */
1.227     brouard  6954:   
1.220     brouard  6955: /* 6eme */
1.202     brouard  6956:   /* CV preval stable (period) for each covariate */
1.237     brouard  6957:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6958:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6959:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6960:       continue;
1.255     brouard  6961:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.227     brouard  6962:       
1.211     brouard  6963:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6964:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6965:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6966:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6967:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6968:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6969:        vlv= nbcode[Tvaraff[k]][lv];
                   6970:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6971:       }
1.237     brouard  6972:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6973:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6974:       }        
1.211     brouard  6975:       fprintf(ficgp,"\n#\n");
1.223     brouard  6976:       if(invalidvarcomb[k1]){
1.227     brouard  6977:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6978:        continue;
1.223     brouard  6979:       }
1.227     brouard  6980:       
1.241     brouard  6981:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6982:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6983: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6984:       k=3; /* Offset */
1.255     brouard  6985:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  6986:        if(i==1)
                   6987:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6988:        else
                   6989:          fprintf(ficgp,", '' ");
1.255     brouard  6990:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  6991:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6992:        for (j=2; j<= nlstate ; j ++)
                   6993:          fprintf(ficgp,"+$%d",k+l+j-1);
                   6994:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  6995:       } /* nlstate */
1.201     brouard  6996:       fprintf(ficgp,"\nset out\n");
1.153     brouard  6997:     } /* end cpt state*/ 
                   6998:   } /* end covariate */  
1.227     brouard  6999:   
                   7000:   
1.220     brouard  7001: /* 7eme */
1.218     brouard  7002:   if(backcast == 1){
1.217     brouard  7003:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7004:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7005:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7006:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7007:        continue;
1.255     brouard  7008:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
                   7009:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7010:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7011:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7012:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7013:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7014:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7015:          vlv= nbcode[Tvaraff[k]][lv];
                   7016:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7017:        }
1.237     brouard  7018:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7019:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7020:        }       
1.227     brouard  7021:        fprintf(ficgp,"\n#\n");
                   7022:        if(invalidvarcomb[k1]){
                   7023:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7024:          continue;
                   7025:        }
                   7026:        
1.241     brouard  7027:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  7028:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7029: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7030:        k=3; /* Offset */
1.255     brouard  7031:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7032:          if(i==1)
                   7033:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7034:          else
                   7035:            fprintf(ficgp,", '' ");
                   7036:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7037:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7038:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7039:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7040:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7041:          /* for (j=2; j<= nlstate ; j ++) */
                   7042:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7043:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7044:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7045:        } /* nlstate */
                   7046:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7047:       } /* end cpt state*/ 
                   7048:     } /* end covariate */  
                   7049:   } /* End if backcast */
                   7050:   
1.223     brouard  7051:   /* 8eme */
1.218     brouard  7052:   if(prevfcast==1){
                   7053:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7054:     
1.237     brouard  7055:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7056:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7057:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7058:        continue;
1.211     brouard  7059:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7060:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7061:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7062:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7063:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7064:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7065:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7066:          vlv= nbcode[Tvaraff[k]][lv];
                   7067:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7068:        }
1.237     brouard  7069:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7070:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7071:        }       
1.227     brouard  7072:        fprintf(ficgp,"\n#\n");
                   7073:        if(invalidvarcomb[k1]){
                   7074:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7075:          continue;
                   7076:        }
                   7077:        
                   7078:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7079:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7080:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7081: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7082:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7083:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7084:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7085:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7086:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7087:          if(i==1){
                   7088:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7089:          }else{
                   7090:            fprintf(ficgp,",\\\n '' ");
                   7091:          }
                   7092:          if(cptcoveff ==0){ /* No covariate */
                   7093:            ioffset=2; /* Age is in 2 */
                   7094:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7095:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7096:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7097:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7098:            fprintf(ficgp," u %d:(", ioffset); 
                   7099:            if(i==nlstate+1)
                   7100:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7101:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7102:            else
                   7103:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7104:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7105:          }else{ /* more than 2 covariates */
                   7106:            if(cptcoveff ==1){
                   7107:              ioffset=4; /* Age is in 4 */
                   7108:            }else{
                   7109:              ioffset=6; /* Age is in 6 */
                   7110:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7111:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7112:            }   
                   7113:            fprintf(ficgp," u %d:(",ioffset); 
                   7114:            kl=0;
                   7115:            strcpy(gplotcondition,"(");
                   7116:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7117:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7118:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7119:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7120:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7121:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7122:              kl++;
                   7123:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7124:              kl++;
                   7125:              if(k <cptcoveff && cptcoveff>1)
                   7126:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7127:            }
                   7128:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7129:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7130:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7131:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7132:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7133:            if(i==nlstate+1){
                   7134:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7135:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7136:            }else{
                   7137:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7138:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7139:            }
                   7140:          } /* end if covariate */
                   7141:        } /* nlstate */
                   7142:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7143:       } /* end cpt state*/
                   7144:     } /* end covariate */
                   7145:   } /* End if prevfcast */
1.227     brouard  7146:   
                   7147:   
1.238     brouard  7148:   /* 9eme writing MLE parameters */
                   7149:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7150:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7151:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7152:     for(k=1; k <=(nlstate+ndeath); k++){
                   7153:       if (k != i) {
1.227     brouard  7154:        fprintf(ficgp,"#   current state %d\n",k);
                   7155:        for(j=1; j <=ncovmodel; j++){
                   7156:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7157:          jk++; 
                   7158:        }
                   7159:        fprintf(ficgp,"\n");
1.126     brouard  7160:       }
                   7161:     }
1.223     brouard  7162:   }
1.187     brouard  7163:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7164:   
1.145     brouard  7165:   /*goto avoid;*/
1.238     brouard  7166:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7167:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7168:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7169:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7170:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7171:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7172:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7173:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7174:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7175:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7176:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7177:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7178:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7179:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7180:   fprintf(ficgp,"#\n");
1.223     brouard  7181:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7182:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7183:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7184:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7185:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7186:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7187:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7188:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7189:        continue;
                   7190:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7191:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7192:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7193:       }        
                   7194:       fprintf(ficgp,"\n#\n");
1.241     brouard  7195:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7196:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7197:       if (ng==1){
                   7198:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7199:        fprintf(ficgp,"\nunset log y");
                   7200:       }else if (ng==2){
                   7201:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7202:        fprintf(ficgp,"\nset log y");
                   7203:       }else if (ng==3){
                   7204:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7205:        fprintf(ficgp,"\nset log y");
                   7206:       }else
                   7207:        fprintf(ficgp,"\nunset title ");
                   7208:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7209:       i=1;
                   7210:       for(k2=1; k2<=nlstate; k2++) {
                   7211:        k3=i;
                   7212:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7213:          if (k != k2){
                   7214:            switch( ng) {
                   7215:            case 1:
                   7216:              if(nagesqr==0)
                   7217:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7218:              else /* nagesqr =1 */
                   7219:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7220:              break;
                   7221:            case 2: /* ng=2 */
                   7222:              if(nagesqr==0)
                   7223:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7224:              else /* nagesqr =1 */
                   7225:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7226:              break;
                   7227:            case 3:
                   7228:              if(nagesqr==0)
                   7229:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7230:              else /* nagesqr =1 */
                   7231:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7232:              break;
                   7233:            }
                   7234:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7235:            ijp=1; /* product no age */
                   7236:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7237:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7238:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7239:              if(j==Tage[ij]) { /* Product by age */
                   7240:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7241:                  if(DummyV[j]==0){
1.237     brouard  7242:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7243:                  }else{ /* quantitative */
                   7244:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7245:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7246:                  }
                   7247:                  ij++;
                   7248:                }
                   7249:              }else if(j==Tprod[ijp]) { /* */ 
                   7250:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7251:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7252:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7253:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7254:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7255:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7256:                    }else{ /* Vn is dummy and Vm is quanti */
                   7257:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7258:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7259:                    }
                   7260:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7261:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7262:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7263:                    }else{ /* Both quanti */
                   7264:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7265:                    }
                   7266:                  }
1.238     brouard  7267:                  ijp++;
1.237     brouard  7268:                }
                   7269:              } else{  /* simple covariate */
                   7270:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7271:                if(Dummy[j]==0){
                   7272:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7273:                }else{ /* quantitative */
                   7274:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7275:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7276:                }
1.237     brouard  7277:              } /* end simple */
                   7278:            } /* end j */
1.223     brouard  7279:          }else{
                   7280:            i=i-ncovmodel;
                   7281:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7282:              fprintf(ficgp," (1.");
                   7283:          }
1.227     brouard  7284:          
1.223     brouard  7285:          if(ng != 1){
                   7286:            fprintf(ficgp,")/(1");
1.227     brouard  7287:            
1.223     brouard  7288:            for(k1=1; k1 <=nlstate; k1++){ 
                   7289:              if(nagesqr==0)
                   7290:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7291:              else /* nagesqr =1 */
                   7292:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7293:               
1.223     brouard  7294:              ij=1;
                   7295:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7296:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7297:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7298:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7299:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7300:                    ij++;
                   7301:                  }
                   7302:                }
                   7303:                else
1.225     brouard  7304:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7305:              }
                   7306:              fprintf(ficgp,")");
                   7307:            }
                   7308:            fprintf(ficgp,")");
                   7309:            if(ng ==2)
                   7310:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7311:            else /* ng= 3 */
                   7312:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7313:          }else{ /* end ng <> 1 */
                   7314:            if( k !=k2) /* logit p11 is hard to draw */
                   7315:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7316:          }
                   7317:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7318:            fprintf(ficgp,",");
                   7319:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7320:            fprintf(ficgp,",");
                   7321:          i=i+ncovmodel;
                   7322:        } /* end k */
                   7323:       } /* end k2 */
                   7324:       fprintf(ficgp,"\n set out\n");
                   7325:     } /* end jk */
                   7326:   } /* end ng */
                   7327:   /* avoid: */
                   7328:   fflush(ficgp); 
1.126     brouard  7329: }  /* end gnuplot */
                   7330: 
                   7331: 
                   7332: /*************** Moving average **************/
1.219     brouard  7333: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7334:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7335:    
1.222     brouard  7336:    int i, cpt, cptcod;
                   7337:    int modcovmax =1;
                   7338:    int mobilavrange, mob;
                   7339:    int iage=0;
                   7340: 
                   7341:    double sum=0.;
                   7342:    double age;
                   7343:    double *sumnewp, *sumnewm;
                   7344:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7345:   
                   7346:   
1.225     brouard  7347:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7348:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7349: 
                   7350:    sumnewp = vector(1,ncovcombmax);
                   7351:    sumnewm = vector(1,ncovcombmax);
                   7352:    agemingood = vector(1,ncovcombmax); 
                   7353:    agemaxgood = vector(1,ncovcombmax);
                   7354: 
                   7355:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7356:      sumnewm[cptcod]=0.;
                   7357:      sumnewp[cptcod]=0.;
                   7358:      agemingood[cptcod]=0;
                   7359:      agemaxgood[cptcod]=0;
                   7360:    }
                   7361:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7362:   
                   7363:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7364:      if(mobilav==1) mobilavrange=5; /* default */
                   7365:      else mobilavrange=mobilav;
                   7366:      for (age=bage; age<=fage; age++)
                   7367:        for (i=1; i<=nlstate;i++)
                   7368:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7369:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7370:      /* We keep the original values on the extreme ages bage, fage and for 
                   7371:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7372:        we use a 5 terms etc. until the borders are no more concerned. 
                   7373:      */ 
                   7374:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7375:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7376:         for (i=1; i<=nlstate;i++){
                   7377:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7378:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7379:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7380:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7381:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7382:             }
                   7383:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7384:           }
                   7385:         }
                   7386:        }/* end age */
                   7387:      }/* end mob */
                   7388:    }else
                   7389:      return -1;
                   7390:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7391:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7392:      if(invalidvarcomb[cptcod]){
                   7393:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7394:        continue;
                   7395:      }
1.219     brouard  7396: 
1.222     brouard  7397:      agemingood[cptcod]=fage-(mob-1)/2;
                   7398:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7399:        sumnewm[cptcod]=0.;
                   7400:        for (i=1; i<=nlstate;i++){
                   7401:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7402:        }
                   7403:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7404:         agemingood[cptcod]=age;
                   7405:        }else{ /* bad */
                   7406:         for (i=1; i<=nlstate;i++){
                   7407:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7408:         } /* i */
                   7409:        } /* end bad */
                   7410:      }/* age */
                   7411:      sum=0.;
                   7412:      for (i=1; i<=nlstate;i++){
                   7413:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7414:      }
                   7415:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7416:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7417:        /* for (i=1; i<=nlstate;i++){ */
                   7418:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7419:        /* } /\* i *\/ */
                   7420:      } /* end bad */
                   7421:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7422:      /* From youngest, finding the oldest wrong */
                   7423:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7424:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7425:        sumnewm[cptcod]=0.;
                   7426:        for (i=1; i<=nlstate;i++){
                   7427:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7428:        }
                   7429:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7430:         agemaxgood[cptcod]=age;
                   7431:        }else{ /* bad */
                   7432:         for (i=1; i<=nlstate;i++){
                   7433:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7434:         } /* i */
                   7435:        } /* end bad */
                   7436:      }/* age */
                   7437:      sum=0.;
                   7438:      for (i=1; i<=nlstate;i++){
                   7439:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7440:      }
                   7441:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7442:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7443:        /* for (i=1; i<=nlstate;i++){ */
                   7444:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7445:        /* } /\* i *\/ */
                   7446:      } /* end bad */
                   7447:                
                   7448:      for (age=bage; age<=fage; age++){
1.235     brouard  7449:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7450:        sumnewp[cptcod]=0.;
                   7451:        sumnewm[cptcod]=0.;
                   7452:        for (i=1; i<=nlstate;i++){
                   7453:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7454:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7455:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7456:        }
                   7457:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7458:      }
                   7459:      /* printf("\n"); */
                   7460:      /* } */
                   7461:      /* brutal averaging */
                   7462:      for (i=1; i<=nlstate;i++){
                   7463:        for (age=1; age<=bage; age++){
                   7464:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7465:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7466:        }       
                   7467:        for (age=fage; age<=AGESUP; age++){
                   7468:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7469:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7470:        }
                   7471:      } /* end i status */
                   7472:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7473:        for (age=1; age<=AGESUP; age++){
                   7474:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7475:         mobaverage[(int)age][i][cptcod]=0.;
                   7476:        }
                   7477:      }
                   7478:    }/* end cptcod */
                   7479:    free_vector(sumnewm,1, ncovcombmax);
                   7480:    free_vector(sumnewp,1, ncovcombmax);
                   7481:    free_vector(agemaxgood,1, ncovcombmax);
                   7482:    free_vector(agemingood,1, ncovcombmax);
                   7483:    return 0;
                   7484:  }/* End movingaverage */
1.218     brouard  7485:  
1.126     brouard  7486: 
                   7487: /************** Forecasting ******************/
1.235     brouard  7488:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7489:   /* proj1, year, month, day of starting projection 
                   7490:      agemin, agemax range of age
                   7491:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7492:      anproj2 year of en of projection (same day and month as proj1).
                   7493:   */
1.235     brouard  7494:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7495:   double agec; /* generic age */
                   7496:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7497:   double *popeffectif,*popcount;
                   7498:   double ***p3mat;
1.218     brouard  7499:   /* double ***mobaverage; */
1.126     brouard  7500:   char fileresf[FILENAMELENGTH];
                   7501: 
                   7502:   agelim=AGESUP;
1.211     brouard  7503:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7504:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7505:      We still use firstpass and lastpass as another selection.
                   7506:   */
1.214     brouard  7507:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7508:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7509:  
1.201     brouard  7510:   strcpy(fileresf,"F_"); 
                   7511:   strcat(fileresf,fileresu);
1.126     brouard  7512:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7513:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7514:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7515:   }
1.235     brouard  7516:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7517:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7518: 
1.225     brouard  7519:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7520: 
                   7521: 
                   7522:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7523:   if (stepm<=12) stepsize=1;
                   7524:   if(estepm < stepm){
                   7525:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7526:   }
                   7527:   else  hstepm=estepm;   
                   7528: 
                   7529:   hstepm=hstepm/stepm; 
                   7530:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7531:                                fractional in yp1 */
                   7532:   anprojmean=yp;
                   7533:   yp2=modf((yp1*12),&yp);
                   7534:   mprojmean=yp;
                   7535:   yp1=modf((yp2*30.5),&yp);
                   7536:   jprojmean=yp;
                   7537:   if(jprojmean==0) jprojmean=1;
                   7538:   if(mprojmean==0) jprojmean=1;
                   7539: 
1.227     brouard  7540:   i1=pow(2,cptcoveff);
1.126     brouard  7541:   if (cptcovn < 1){i1=1;}
                   7542:   
                   7543:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7544:   
                   7545:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7546:   
1.126     brouard  7547: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7548:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7549:   for(k=1; k<=i1;k++){
1.253     brouard  7550:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7551:       continue;
1.227     brouard  7552:     if(invalidvarcomb[k]){
                   7553:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7554:       continue;
                   7555:     }
                   7556:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7557:     for(j=1;j<=cptcoveff;j++) {
                   7558:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7559:     }
1.235     brouard  7560:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7561:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7562:     }
1.227     brouard  7563:     fprintf(ficresf," yearproj age");
                   7564:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7565:       for(i=1; i<=nlstate;i++)               
                   7566:        fprintf(ficresf," p%d%d",i,j);
                   7567:       fprintf(ficresf," wp.%d",j);
                   7568:     }
                   7569:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7570:       fprintf(ficresf,"\n");
                   7571:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7572:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7573:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7574:        nhstepm = nhstepm/hstepm; 
                   7575:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7576:        oldm=oldms;savm=savms;
1.235     brouard  7577:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7578:        
                   7579:        for (h=0; h<=nhstepm; h++){
                   7580:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7581:            fprintf(ficresf,"\n");
                   7582:            for(j=1;j<=cptcoveff;j++) 
                   7583:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7584:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7585:          } 
                   7586:          for(j=1; j<=nlstate+ndeath;j++) {
                   7587:            ppij=0.;
                   7588:            for(i=1; i<=nlstate;i++) {
                   7589:              if (mobilav==1) 
                   7590:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7591:              else {
                   7592:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7593:              }
                   7594:              if (h*hstepm/YEARM*stepm== yearp) {
                   7595:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7596:              }
                   7597:            } /* end i */
                   7598:            if (h*hstepm/YEARM*stepm==yearp) {
                   7599:              fprintf(ficresf," %.3f", ppij);
                   7600:            }
                   7601:          }/* end j */
                   7602:        } /* end h */
                   7603:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7604:       } /* end agec */
                   7605:     } /* end yearp */
                   7606:   } /* end  k */
1.219     brouard  7607:        
1.126     brouard  7608:   fclose(ficresf);
1.215     brouard  7609:   printf("End of Computing forecasting \n");
                   7610:   fprintf(ficlog,"End of Computing forecasting\n");
                   7611: 
1.126     brouard  7612: }
                   7613: 
1.218     brouard  7614: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7615: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7616: /*   /\* back1, year, month, day of starting backection  */
                   7617: /*      agemin, agemax range of age */
                   7618: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7619: /*      anback2 year of en of backection (same day and month as back1). */
                   7620: /*   *\/ */
                   7621: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7622: /*   double agec; /\* generic age *\/ */
                   7623: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7624: /*   double *popeffectif,*popcount; */
                   7625: /*   double ***p3mat; */
                   7626: /*   /\* double ***mobaverage; *\/ */
                   7627: /*   char fileresfb[FILENAMELENGTH]; */
                   7628:        
                   7629: /*   agelim=AGESUP; */
                   7630: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7631: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7632: /*      We still use firstpass and lastpass as another selection. */
                   7633: /*   *\/ */
                   7634: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7635: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7636: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7637:        
                   7638: /*   strcpy(fileresfb,"FB_");  */
                   7639: /*   strcat(fileresfb,fileresu); */
                   7640: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7641: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7642: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7643: /*   } */
                   7644: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7645: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7646:        
1.225     brouard  7647: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7648:        
                   7649: /*   /\* if (mobilav!=0) { *\/ */
                   7650: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7651: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7652: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7653: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7654: /*   /\*   } *\/ */
                   7655: /*   /\* } *\/ */
                   7656:        
                   7657: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7658: /*   if (stepm<=12) stepsize=1; */
                   7659: /*   if(estepm < stepm){ */
                   7660: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7661: /*   } */
                   7662: /*   else  hstepm=estepm;    */
                   7663:        
                   7664: /*   hstepm=hstepm/stepm;  */
                   7665: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7666: /*                                fractional in yp1 *\/ */
                   7667: /*   anprojmean=yp; */
                   7668: /*   yp2=modf((yp1*12),&yp); */
                   7669: /*   mprojmean=yp; */
                   7670: /*   yp1=modf((yp2*30.5),&yp); */
                   7671: /*   jprojmean=yp; */
                   7672: /*   if(jprojmean==0) jprojmean=1; */
                   7673: /*   if(mprojmean==0) jprojmean=1; */
                   7674:        
1.225     brouard  7675: /*   i1=cptcoveff; */
1.218     brouard  7676: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7677:   
1.218     brouard  7678: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7679:   
1.218     brouard  7680: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7681:        
                   7682: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7683: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7684: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7685: /*       k=k+1; */
                   7686: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7687: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7688: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7689: /*       } */
                   7690: /*       fprintf(ficresfb," yearbproj age"); */
                   7691: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7692: /*                             for(i=1; i<=nlstate;i++)               */
                   7693: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7694: /*                             fprintf(ficresfb," p.%d",j); */
                   7695: /*       } */
                   7696: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7697: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7698: /*                             fprintf(ficresfb,"\n"); */
                   7699: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7700: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7701: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7702: /*                                     nhstepm = nhstepm/hstepm;  */
                   7703: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7704: /*                                     oldm=oldms;savm=savms; */
                   7705: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7706: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7707: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7708: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7709: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7710: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7711: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7712: /*                                             }  */
                   7713: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7714: /*                                                     ppij=0.; */
                   7715: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7716: /*                                                             if (mobilav==1)  */
                   7717: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7718: /*                                                             else { */
                   7719: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7720: /*                                                             } */
                   7721: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7722: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7723: /*                                                             } */
                   7724: /*                                                     } /\* end i *\/ */
                   7725: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7726: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7727: /*                                                     } */
                   7728: /*                                             }/\* end j *\/ */
                   7729: /*                                     } /\* end h *\/ */
                   7730: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7731: /*                             } /\* end agec *\/ */
                   7732: /*       } /\* end yearp *\/ */
                   7733: /*     } /\* end cptcod *\/ */
                   7734: /*   } /\* end  cptcov *\/ */
                   7735:        
                   7736: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7737:        
                   7738: /*   fclose(ficresfb); */
                   7739: /*   printf("End of Computing Back forecasting \n"); */
                   7740: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7741:        
1.218     brouard  7742: /* } */
1.217     brouard  7743: 
1.126     brouard  7744: /************** Forecasting *****not tested NB*************/
1.227     brouard  7745: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7746:   
1.227     brouard  7747: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7748: /*   int *popage; */
                   7749: /*   double calagedatem, agelim, kk1, kk2; */
                   7750: /*   double *popeffectif,*popcount; */
                   7751: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7752: /*   /\* double ***mobaverage; *\/ */
                   7753: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7754: 
1.227     brouard  7755: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7756: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7757: /*   agelim=AGESUP; */
                   7758: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7759:   
1.227     brouard  7760: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7761:   
                   7762:   
1.227     brouard  7763: /*   strcpy(filerespop,"POP_");  */
                   7764: /*   strcat(filerespop,fileresu); */
                   7765: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7766: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7767: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7768: /*   } */
                   7769: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7770: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7771: 
1.227     brouard  7772: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7773: 
1.227     brouard  7774: /*   /\* if (mobilav!=0) { *\/ */
                   7775: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7776: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7777: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7778: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7779: /*   /\*   } *\/ */
                   7780: /*   /\* } *\/ */
1.126     brouard  7781: 
1.227     brouard  7782: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7783: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7784:   
1.227     brouard  7785: /*   agelim=AGESUP; */
1.126     brouard  7786:   
1.227     brouard  7787: /*   hstepm=1; */
                   7788: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7789:        
1.227     brouard  7790: /*   if (popforecast==1) { */
                   7791: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7792: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7793: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7794: /*     }  */
                   7795: /*     popage=ivector(0,AGESUP); */
                   7796: /*     popeffectif=vector(0,AGESUP); */
                   7797: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7798:     
1.227     brouard  7799: /*     i=1;    */
                   7800: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7801:     
1.227     brouard  7802: /*     imx=i; */
                   7803: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7804: /*   } */
1.218     brouard  7805:   
1.227     brouard  7806: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7807: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7808: /*       k=k+1; */
                   7809: /*       fprintf(ficrespop,"\n#******"); */
                   7810: /*       for(j=1;j<=cptcoveff;j++) { */
                   7811: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7812: /*       } */
                   7813: /*       fprintf(ficrespop,"******\n"); */
                   7814: /*       fprintf(ficrespop,"# Age"); */
                   7815: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7816: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7817:       
1.227     brouard  7818: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7819: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7820:        
1.227     brouard  7821: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7822: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7823: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7824:          
1.227     brouard  7825: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7826: /*       oldm=oldms;savm=savms; */
                   7827: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7828:          
1.227     brouard  7829: /*       for (h=0; h<=nhstepm; h++){ */
                   7830: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7831: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7832: /*         }  */
                   7833: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7834: /*           kk1=0.;kk2=0; */
                   7835: /*           for(i=1; i<=nlstate;i++) {               */
                   7836: /*             if (mobilav==1)  */
                   7837: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7838: /*             else { */
                   7839: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7840: /*             } */
                   7841: /*           } */
                   7842: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7843: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7844: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7845: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7846: /*           } */
                   7847: /*         } */
                   7848: /*         for(i=1; i<=nlstate;i++){ */
                   7849: /*           kk1=0.; */
                   7850: /*           for(j=1; j<=nlstate;j++){ */
                   7851: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7852: /*           } */
                   7853: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7854: /*         } */
1.218     brouard  7855:            
1.227     brouard  7856: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7857: /*           for(j=1; j<=nlstate;j++)  */
                   7858: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7859: /*       } */
                   7860: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7861: /*     } */
                   7862: /*       } */
1.218     brouard  7863:       
1.227     brouard  7864: /*       /\******\/ */
1.218     brouard  7865:       
1.227     brouard  7866: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7867: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7868: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7869: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7870: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7871:          
1.227     brouard  7872: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7873: /*       oldm=oldms;savm=savms; */
                   7874: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7875: /*       for (h=0; h<=nhstepm; h++){ */
                   7876: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7877: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7878: /*         }  */
                   7879: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7880: /*           kk1=0.;kk2=0; */
                   7881: /*           for(i=1; i<=nlstate;i++) {               */
                   7882: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7883: /*           } */
                   7884: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7885: /*         } */
                   7886: /*       } */
                   7887: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7888: /*     } */
                   7889: /*       } */
                   7890: /*     }  */
                   7891: /*   } */
1.218     brouard  7892:   
1.227     brouard  7893: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7894:   
1.227     brouard  7895: /*   if (popforecast==1) { */
                   7896: /*     free_ivector(popage,0,AGESUP); */
                   7897: /*     free_vector(popeffectif,0,AGESUP); */
                   7898: /*     free_vector(popcount,0,AGESUP); */
                   7899: /*   } */
                   7900: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7901: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7902: /*   fclose(ficrespop); */
                   7903: /* } /\* End of popforecast *\/ */
1.218     brouard  7904:  
1.126     brouard  7905: int fileappend(FILE *fichier, char *optionfich)
                   7906: {
                   7907:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7908:     printf("Problem with file: %s\n", optionfich);
                   7909:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7910:     return (0);
                   7911:   }
                   7912:   fflush(fichier);
                   7913:   return (1);
                   7914: }
                   7915: 
                   7916: 
                   7917: /**************** function prwizard **********************/
                   7918: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7919: {
                   7920: 
                   7921:   /* Wizard to print covariance matrix template */
                   7922: 
1.164     brouard  7923:   char ca[32], cb[32];
                   7924:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7925:   int numlinepar;
                   7926: 
                   7927:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7928:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7929:   for(i=1; i <=nlstate; i++){
                   7930:     jj=0;
                   7931:     for(j=1; j <=nlstate+ndeath; j++){
                   7932:       if(j==i) continue;
                   7933:       jj++;
                   7934:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7935:       printf("%1d%1d",i,j);
                   7936:       fprintf(ficparo,"%1d%1d",i,j);
                   7937:       for(k=1; k<=ncovmodel;k++){
                   7938:        /*        printf(" %lf",param[i][j][k]); */
                   7939:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7940:        printf(" 0.");
                   7941:        fprintf(ficparo," 0.");
                   7942:       }
                   7943:       printf("\n");
                   7944:       fprintf(ficparo,"\n");
                   7945:     }
                   7946:   }
                   7947:   printf("# Scales (for hessian or gradient estimation)\n");
                   7948:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7949:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7950:   for(i=1; i <=nlstate; i++){
                   7951:     jj=0;
                   7952:     for(j=1; j <=nlstate+ndeath; j++){
                   7953:       if(j==i) continue;
                   7954:       jj++;
                   7955:       fprintf(ficparo,"%1d%1d",i,j);
                   7956:       printf("%1d%1d",i,j);
                   7957:       fflush(stdout);
                   7958:       for(k=1; k<=ncovmodel;k++){
                   7959:        /*      printf(" %le",delti3[i][j][k]); */
                   7960:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7961:        printf(" 0.");
                   7962:        fprintf(ficparo," 0.");
                   7963:       }
                   7964:       numlinepar++;
                   7965:       printf("\n");
                   7966:       fprintf(ficparo,"\n");
                   7967:     }
                   7968:   }
                   7969:   printf("# Covariance matrix\n");
                   7970: /* # 121 Var(a12)\n\ */
                   7971: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7972: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7973: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7974: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7975: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7976: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7977: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7978:   fflush(stdout);
                   7979:   fprintf(ficparo,"# Covariance matrix\n");
                   7980:   /* # 121 Var(a12)\n\ */
                   7981:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7982:   /* #   ...\n\ */
                   7983:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7984:   
                   7985:   for(itimes=1;itimes<=2;itimes++){
                   7986:     jj=0;
                   7987:     for(i=1; i <=nlstate; i++){
                   7988:       for(j=1; j <=nlstate+ndeath; j++){
                   7989:        if(j==i) continue;
                   7990:        for(k=1; k<=ncovmodel;k++){
                   7991:          jj++;
                   7992:          ca[0]= k+'a'-1;ca[1]='\0';
                   7993:          if(itimes==1){
                   7994:            printf("#%1d%1d%d",i,j,k);
                   7995:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   7996:          }else{
                   7997:            printf("%1d%1d%d",i,j,k);
                   7998:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   7999:            /*  printf(" %.5le",matcov[i][j]); */
                   8000:          }
                   8001:          ll=0;
                   8002:          for(li=1;li <=nlstate; li++){
                   8003:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8004:              if(lj==li) continue;
                   8005:              for(lk=1;lk<=ncovmodel;lk++){
                   8006:                ll++;
                   8007:                if(ll<=jj){
                   8008:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8009:                  if(ll<jj){
                   8010:                    if(itimes==1){
                   8011:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8012:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8013:                    }else{
                   8014:                      printf(" 0.");
                   8015:                      fprintf(ficparo," 0.");
                   8016:                    }
                   8017:                  }else{
                   8018:                    if(itimes==1){
                   8019:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8020:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8021:                    }else{
                   8022:                      printf(" 0.");
                   8023:                      fprintf(ficparo," 0.");
                   8024:                    }
                   8025:                  }
                   8026:                }
                   8027:              } /* end lk */
                   8028:            } /* end lj */
                   8029:          } /* end li */
                   8030:          printf("\n");
                   8031:          fprintf(ficparo,"\n");
                   8032:          numlinepar++;
                   8033:        } /* end k*/
                   8034:       } /*end j */
                   8035:     } /* end i */
                   8036:   } /* end itimes */
                   8037: 
                   8038: } /* end of prwizard */
                   8039: /******************* Gompertz Likelihood ******************************/
                   8040: double gompertz(double x[])
                   8041: { 
                   8042:   double A,B,L=0.0,sump=0.,num=0.;
                   8043:   int i,n=0; /* n is the size of the sample */
                   8044: 
1.220     brouard  8045:   for (i=1;i<=imx ; i++) {
1.126     brouard  8046:     sump=sump+weight[i];
                   8047:     /*    sump=sump+1;*/
                   8048:     num=num+1;
                   8049:   }
                   8050:  
                   8051:  
                   8052:   /* for (i=0; i<=imx; i++) 
                   8053:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8054: 
                   8055:   for (i=1;i<=imx ; i++)
                   8056:     {
                   8057:       if (cens[i] == 1 && wav[i]>1)
                   8058:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8059:       
                   8060:       if (cens[i] == 0 && wav[i]>1)
                   8061:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8062:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8063:       
                   8064:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8065:       if (wav[i] > 1 ) { /* ??? */
                   8066:        L=L+A*weight[i];
                   8067:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8068:       }
                   8069:     }
                   8070: 
                   8071:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8072:  
                   8073:   return -2*L*num/sump;
                   8074: }
                   8075: 
1.136     brouard  8076: #ifdef GSL
                   8077: /******************* Gompertz_f Likelihood ******************************/
                   8078: double gompertz_f(const gsl_vector *v, void *params)
                   8079: { 
                   8080:   double A,B,LL=0.0,sump=0.,num=0.;
                   8081:   double *x= (double *) v->data;
                   8082:   int i,n=0; /* n is the size of the sample */
                   8083: 
                   8084:   for (i=0;i<=imx-1 ; i++) {
                   8085:     sump=sump+weight[i];
                   8086:     /*    sump=sump+1;*/
                   8087:     num=num+1;
                   8088:   }
                   8089:  
                   8090:  
                   8091:   /* for (i=0; i<=imx; i++) 
                   8092:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8093:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8094:   for (i=1;i<=imx ; i++)
                   8095:     {
                   8096:       if (cens[i] == 1 && wav[i]>1)
                   8097:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8098:       
                   8099:       if (cens[i] == 0 && wav[i]>1)
                   8100:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8101:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8102:       
                   8103:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8104:       if (wav[i] > 1 ) { /* ??? */
                   8105:        LL=LL+A*weight[i];
                   8106:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8107:       }
                   8108:     }
                   8109: 
                   8110:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8111:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8112:  
                   8113:   return -2*LL*num/sump;
                   8114: }
                   8115: #endif
                   8116: 
1.126     brouard  8117: /******************* Printing html file ***********/
1.201     brouard  8118: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8119:                  int lastpass, int stepm, int weightopt, char model[],\
                   8120:                  int imx,  double p[],double **matcov,double agemortsup){
                   8121:   int i,k;
                   8122: 
                   8123:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8124:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8125:   for (i=1;i<=2;i++) 
                   8126:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8127:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8128:   fprintf(fichtm,"</ul>");
                   8129: 
                   8130: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8131: 
                   8132:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8133: 
                   8134:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8135:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8136: 
                   8137:  
                   8138:   fflush(fichtm);
                   8139: }
                   8140: 
                   8141: /******************* Gnuplot file **************/
1.201     brouard  8142: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8143: 
                   8144:   char dirfileres[132],optfileres[132];
1.164     brouard  8145: 
1.126     brouard  8146:   int ng;
                   8147: 
                   8148: 
                   8149:   /*#ifdef windows */
                   8150:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8151:     /*#endif */
                   8152: 
                   8153: 
                   8154:   strcpy(dirfileres,optionfilefiname);
                   8155:   strcpy(optfileres,"vpl");
1.199     brouard  8156:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8157:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8158:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8159:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8160:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8161: 
                   8162: } 
                   8163: 
1.136     brouard  8164: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8165: {
1.126     brouard  8166: 
1.136     brouard  8167:   /*-------- data file ----------*/
                   8168:   FILE *fic;
                   8169:   char dummy[]="                         ";
1.240     brouard  8170:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8171:   int lstra;
1.136     brouard  8172:   int linei, month, year,iout;
                   8173:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8174:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8175:   char *stratrunc;
1.223     brouard  8176: 
1.240     brouard  8177:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8178:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8179: 
1.240     brouard  8180:   for(v=1; v <=ncovcol;v++){
                   8181:     DummyV[v]=0;
                   8182:     FixedV[v]=0;
                   8183:   }
                   8184:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8185:     DummyV[v]=1;
                   8186:     FixedV[v]=0;
                   8187:   }
                   8188:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8189:     DummyV[v]=0;
                   8190:     FixedV[v]=1;
                   8191:   }
                   8192:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8193:     DummyV[v]=1;
                   8194:     FixedV[v]=1;
                   8195:   }
                   8196:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8197:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8198:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8199:   }
1.126     brouard  8200: 
1.136     brouard  8201:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8202:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8203:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8204:   }
1.126     brouard  8205: 
1.136     brouard  8206:   i=1;
                   8207:   linei=0;
                   8208:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8209:     linei=linei+1;
                   8210:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8211:       if(line[j] == '\t')
                   8212:        line[j] = ' ';
                   8213:     }
                   8214:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8215:       ;
                   8216:     };
                   8217:     line[j+1]=0;  /* Trims blanks at end of line */
                   8218:     if(line[0]=='#'){
                   8219:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8220:       printf("Comment line\n%s\n",line);
                   8221:       continue;
                   8222:     }
                   8223:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8224:     strcpy(line, linetmp);
1.223     brouard  8225:     
                   8226:     /* Loops on waves */
                   8227:     for (j=maxwav;j>=1;j--){
                   8228:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8229:        cutv(stra, strb, line, ' '); 
                   8230:        if(strb[0]=='.') { /* Missing value */
                   8231:          lval=-1;
                   8232:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8233:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8234:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8235:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8236:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8237:            return 1;
                   8238:          }
                   8239:        }else{
                   8240:          errno=0;
                   8241:          /* what_kind_of_number(strb); */
                   8242:          dval=strtod(strb,&endptr); 
                   8243:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8244:          /* if(strb != endptr && *endptr == '\0') */
                   8245:          /*    dval=dlval; */
                   8246:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8247:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8248:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8249:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8250:            return 1;
                   8251:          }
                   8252:          cotqvar[j][iv][i]=dval; 
                   8253:          cotvar[j][ntv+iv][i]=dval; 
                   8254:        }
                   8255:        strcpy(line,stra);
1.223     brouard  8256:       }/* end loop ntqv */
1.225     brouard  8257:       
1.223     brouard  8258:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8259:        cutv(stra, strb, line, ' '); 
                   8260:        if(strb[0]=='.') { /* Missing value */
                   8261:          lval=-1;
                   8262:        }else{
                   8263:          errno=0;
                   8264:          lval=strtol(strb,&endptr,10); 
                   8265:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8266:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8267:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8268:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8269:            return 1;
                   8270:          }
                   8271:        }
                   8272:        if(lval <-1 || lval >1){
                   8273:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8274:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8275:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8276:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8277:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8278:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8279:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8280:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8281:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8282:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8283:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8284:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8285:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8286:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8287:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8288:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8289:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8290:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8291:          return 1;
                   8292:        }
                   8293:        cotvar[j][iv][i]=(double)(lval);
                   8294:        strcpy(line,stra);
1.223     brouard  8295:       }/* end loop ntv */
1.225     brouard  8296:       
1.223     brouard  8297:       /* Statuses  at wave */
1.137     brouard  8298:       cutv(stra, strb, line, ' '); 
1.223     brouard  8299:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8300:        lval=-1;
1.136     brouard  8301:       }else{
1.238     brouard  8302:        errno=0;
                   8303:        lval=strtol(strb,&endptr,10); 
                   8304:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8305:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8306:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8307:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8308:          return 1;
                   8309:        }
1.136     brouard  8310:       }
1.225     brouard  8311:       
1.136     brouard  8312:       s[j][i]=lval;
1.225     brouard  8313:       
1.223     brouard  8314:       /* Date of Interview */
1.136     brouard  8315:       strcpy(line,stra);
                   8316:       cutv(stra, strb,line,' ');
1.169     brouard  8317:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8318:       }
1.169     brouard  8319:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8320:        month=99;
                   8321:        year=9999;
1.136     brouard  8322:       }else{
1.225     brouard  8323:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8324:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8325:        return 1;
1.136     brouard  8326:       }
                   8327:       anint[j][i]= (double) year; 
                   8328:       mint[j][i]= (double)month; 
                   8329:       strcpy(line,stra);
1.223     brouard  8330:     } /* End loop on waves */
1.225     brouard  8331:     
1.223     brouard  8332:     /* Date of death */
1.136     brouard  8333:     cutv(stra, strb,line,' '); 
1.169     brouard  8334:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8335:     }
1.169     brouard  8336:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8337:       month=99;
                   8338:       year=9999;
                   8339:     }else{
1.141     brouard  8340:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8341:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8342:       return 1;
1.136     brouard  8343:     }
                   8344:     andc[i]=(double) year; 
                   8345:     moisdc[i]=(double) month; 
                   8346:     strcpy(line,stra);
                   8347:     
1.223     brouard  8348:     /* Date of birth */
1.136     brouard  8349:     cutv(stra, strb,line,' '); 
1.169     brouard  8350:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8351:     }
1.169     brouard  8352:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8353:       month=99;
                   8354:       year=9999;
                   8355:     }else{
1.141     brouard  8356:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8357:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8358:       return 1;
1.136     brouard  8359:     }
                   8360:     if (year==9999) {
1.141     brouard  8361:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8362:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8363:       return 1;
                   8364:       
1.136     brouard  8365:     }
                   8366:     annais[i]=(double)(year);
                   8367:     moisnais[i]=(double)(month); 
                   8368:     strcpy(line,stra);
1.225     brouard  8369:     
1.223     brouard  8370:     /* Sample weight */
1.136     brouard  8371:     cutv(stra, strb,line,' '); 
                   8372:     errno=0;
                   8373:     dval=strtod(strb,&endptr); 
                   8374:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8375:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8376:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8377:       fflush(ficlog);
                   8378:       return 1;
                   8379:     }
                   8380:     weight[i]=dval; 
                   8381:     strcpy(line,stra);
1.225     brouard  8382:     
1.223     brouard  8383:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8384:       cutv(stra, strb, line, ' '); 
                   8385:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8386:        lval=-1;
1.223     brouard  8387:       }else{
1.225     brouard  8388:        errno=0;
                   8389:        /* what_kind_of_number(strb); */
                   8390:        dval=strtod(strb,&endptr);
                   8391:        /* if(strb != endptr && *endptr == '\0') */
                   8392:        /*   dval=dlval; */
                   8393:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8394:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8395:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8396:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8397:          return 1;
                   8398:        }
                   8399:        coqvar[iv][i]=dval; 
1.226     brouard  8400:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8401:       }
                   8402:       strcpy(line,stra);
                   8403:     }/* end loop nqv */
1.136     brouard  8404:     
1.223     brouard  8405:     /* Covariate values */
1.136     brouard  8406:     for (j=ncovcol;j>=1;j--){
                   8407:       cutv(stra, strb,line,' '); 
1.223     brouard  8408:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8409:        lval=-1;
1.136     brouard  8410:       }else{
1.225     brouard  8411:        errno=0;
                   8412:        lval=strtol(strb,&endptr,10); 
                   8413:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8414:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8415:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8416:          return 1;
                   8417:        }
1.136     brouard  8418:       }
                   8419:       if(lval <-1 || lval >1){
1.225     brouard  8420:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8421:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8422:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8423:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8424:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8425:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8426:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8427:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8428:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8429:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8430:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8431:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8432:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8433:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8434:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8435:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8436:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8437:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8438:        return 1;
1.136     brouard  8439:       }
                   8440:       covar[j][i]=(double)(lval);
                   8441:       strcpy(line,stra);
                   8442:     }  
                   8443:     lstra=strlen(stra);
1.225     brouard  8444:     
1.136     brouard  8445:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8446:       stratrunc = &(stra[lstra-9]);
                   8447:       num[i]=atol(stratrunc);
                   8448:     }
                   8449:     else
                   8450:       num[i]=atol(stra);
                   8451:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8452:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8453:     
                   8454:     i=i+1;
                   8455:   } /* End loop reading  data */
1.225     brouard  8456:   
1.136     brouard  8457:   *imax=i-1; /* Number of individuals */
                   8458:   fclose(fic);
1.225     brouard  8459:   
1.136     brouard  8460:   return (0);
1.164     brouard  8461:   /* endread: */
1.225     brouard  8462:   printf("Exiting readdata: ");
                   8463:   fclose(fic);
                   8464:   return (1);
1.223     brouard  8465: }
1.126     brouard  8466: 
1.234     brouard  8467: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8468:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8469:   while (*p2 == ' ')
1.234     brouard  8470:     p2++; 
                   8471:   /* while ((*p1++ = *p2++) !=0) */
                   8472:   /*   ; */
                   8473:   /* do */
                   8474:   /*   while (*p2 == ' ') */
                   8475:   /*     p2++; */
                   8476:   /* while (*p1++ == *p2++); */
                   8477:   *stri=p2; 
1.145     brouard  8478: }
                   8479: 
1.235     brouard  8480: int decoderesult ( char resultline[], int nres)
1.230     brouard  8481: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8482: {
1.235     brouard  8483:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8484:   char resultsav[MAXLINE];
1.234     brouard  8485:   int resultmodel[MAXLINE];
                   8486:   int modelresult[MAXLINE];
1.230     brouard  8487:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8488: 
1.234     brouard  8489:   removefirstspace(&resultline);
1.233     brouard  8490:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8491: 
                   8492:   if (strstr(resultline,"v") !=0){
                   8493:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8494:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8495:     return 1;
                   8496:   }
                   8497:   trimbb(resultsav, resultline);
                   8498:   if (strlen(resultsav) >1){
                   8499:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8500:   }
1.253     brouard  8501:   if(j == 0){ /* Resultline but no = */
                   8502:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8503:     return (0);
                   8504:   }
                   8505:     
1.234     brouard  8506:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8507:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8508:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8509:   }
                   8510:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8511:     if(nbocc(resultsav,'=') >1){
                   8512:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8513:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8514:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8515:     }else
                   8516:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8517:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8518:     
1.230     brouard  8519:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8520:     Tvarsel[k]=atoi(strc);
                   8521:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8522:     /* cptcovsel++;     */
                   8523:     if (nbocc(stra,'=') >0)
                   8524:       strcpy(resultsav,stra); /* and analyzes it */
                   8525:   }
1.235     brouard  8526:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8527:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8528:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8529:       match=0;
1.236     brouard  8530:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8531:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8532:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8533:          match=1;
                   8534:          break;
                   8535:        }
                   8536:       }
                   8537:       if(match == 0){
                   8538:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8539:       }
                   8540:     }
                   8541:   }
1.235     brouard  8542:   /* Checking for missing or useless values in comparison of current model needs */
                   8543:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8544:     match=0;
1.235     brouard  8545:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8546:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8547:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8548:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8549:          ++match;
                   8550:        }
                   8551:       }
                   8552:     }
                   8553:     if(match == 0){
                   8554:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8555:     }else if(match > 1){
                   8556:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8557:     }
                   8558:   }
1.235     brouard  8559:       
1.234     brouard  8560:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8561:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8562:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8563:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8564:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8565:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8566:   /*    1 0 0 0 */
                   8567:   /*    2 1 0 0 */
                   8568:   /*    3 0 1 0 */ 
                   8569:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8570:   /*    5 0 0 1 */
                   8571:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8572:   /*    7 0 1 1 */
                   8573:   /*    8 1 1 1 */
1.237     brouard  8574:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8575:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8576:   /* V5*age V5 known which value for nres?  */
                   8577:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8578:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8579:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8580:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8581:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8582:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8583:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8584:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8585:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8586:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8587:       k4++;;
                   8588:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8589:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8590:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8591:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8592:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8593:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8594:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8595:       k4q++;;
                   8596:     }
                   8597:   }
1.234     brouard  8598:   
1.235     brouard  8599:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8600:   return (0);
                   8601: }
1.235     brouard  8602: 
1.230     brouard  8603: int decodemodel( char model[], int lastobs)
                   8604:  /**< This routine decodes the model and returns:
1.224     brouard  8605:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8606:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8607:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8608:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8609:        * - cptcovage number of covariates with age*products =2
                   8610:        * - cptcovs number of simple covariates
                   8611:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8612:        *     which is a new column after the 9 (ncovcol) variables. 
                   8613:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8614:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8615:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8616:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8617:        */
1.136     brouard  8618: {
1.238     brouard  8619:   int i, j, k, ks, v;
1.227     brouard  8620:   int  j1, k1, k2, k3, k4;
1.136     brouard  8621:   char modelsav[80];
1.145     brouard  8622:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8623:   char *strpt;
1.136     brouard  8624: 
1.145     brouard  8625:   /*removespace(model);*/
1.136     brouard  8626:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8627:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8628:     if (strstr(model,"AGE") !=0){
1.192     brouard  8629:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8630:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8631:       return 1;
                   8632:     }
1.141     brouard  8633:     if (strstr(model,"v") !=0){
                   8634:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8635:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8636:       return 1;
                   8637:     }
1.187     brouard  8638:     strcpy(modelsav,model); 
                   8639:     if ((strpt=strstr(model,"age*age")) !=0){
                   8640:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8641:       if(strpt != model){
1.234     brouard  8642:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8643:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8644:  corresponding column of parameters.\n",model);
1.234     brouard  8645:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8646:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8647:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8648:        return 1;
1.225     brouard  8649:       }
1.187     brouard  8650:       nagesqr=1;
                   8651:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8652:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8653:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8654:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8655:       else 
1.234     brouard  8656:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8657:     }else
                   8658:       nagesqr=0;
                   8659:     if (strlen(modelsav) >1){
                   8660:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8661:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8662:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8663:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8664:                     * cst, age and age*age 
                   8665:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8666:       /* including age products which are counted in cptcovage.
                   8667:        * but the covariates which are products must be treated 
                   8668:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8669:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8670:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8671:       
                   8672:       
1.187     brouard  8673:       /*   Design
                   8674:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8675:        *  <          ncovcol=8                >
                   8676:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8677:        *   k=  1    2      3       4     5       6      7        8
                   8678:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8679:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8680:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8681:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8682:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8683:        *  Tage[++cptcovage]=k
                   8684:        *       if products, new covar are created after ncovcol with k1
                   8685:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8686:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8687:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8688:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8689:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8690:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8691:        *  <          ncovcol=8                >
                   8692:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8693:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8694:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8695:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8696:        * p Tprod[1]@2={                         6, 5}
                   8697:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8698:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8699:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8700:        *How to reorganize?
                   8701:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8702:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8703:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8704:        * Struct []
                   8705:        */
1.225     brouard  8706:       
1.187     brouard  8707:       /* This loop fills the array Tvar from the string 'model'.*/
                   8708:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8709:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8710:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8711:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8712:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8713:       /*       k=1 Tvar[1]=2 (from V2) */
                   8714:       /*       k=5 Tvar[5] */
                   8715:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8716:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8717:       /*       } */
1.198     brouard  8718:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8719:       /*
                   8720:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8721:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8722:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8723:       }
1.187     brouard  8724:       cptcovage=0;
                   8725:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8726:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8727:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8728:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8729:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8730:        /*scanf("%d",i);*/
                   8731:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8732:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8733:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8734:            /* covar is not filled and then is empty */
                   8735:            cptcovprod--;
                   8736:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8737:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8738:            Typevar[k]=1;  /* 1 for age product */
                   8739:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8740:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8741:            /*printf("stre=%s ", stre);*/
                   8742:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8743:            cptcovprod--;
                   8744:            cutl(stre,strb,strc,'V');
                   8745:            Tvar[k]=atoi(stre);
                   8746:            Typevar[k]=1;  /* 1 for age product */
                   8747:            cptcovage++;
                   8748:            Tage[cptcovage]=k;
                   8749:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8750:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8751:            cptcovn++;
                   8752:            cptcovprodnoage++;k1++;
                   8753:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8754:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8755:                                                because this model-covariate is a construction we invent a new column
                   8756:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8757:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8758:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8759:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8760:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8761:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8762:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8763:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8764:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8765:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8766:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8767:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8768:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8769:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8770:            for (i=1; i<=lastobs;i++){
                   8771:              /* Computes the new covariate which is a product of
                   8772:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8773:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8774:            }
                   8775:          } /* End age is not in the model */
                   8776:        } /* End if model includes a product */
                   8777:        else { /* no more sum */
                   8778:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8779:          /*  scanf("%d",i);*/
                   8780:          cutl(strd,strc,strb,'V');
                   8781:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8782:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8783:          Tvar[k]=atoi(strd);
                   8784:          Typevar[k]=0;  /* 0 for simple covariates */
                   8785:        }
                   8786:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8787:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8788:                                  scanf("%d",i);*/
1.187     brouard  8789:       } /* end of loop + on total covariates */
                   8790:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8791:   } /* end if strlen(model == 0) */
1.136     brouard  8792:   
                   8793:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8794:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8795:   
1.136     brouard  8796:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8797:      printf("cptcovprod=%d ", cptcovprod);
                   8798:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8799:      scanf("%d ",i);*/
                   8800: 
                   8801: 
1.230     brouard  8802: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8803:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8804: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8805:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8806:    k =           1    2   3     4       5       6      7      8        9
                   8807:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8808:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8809:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8810:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8811:          Tmodelind[combination of covar]=k;
1.225     brouard  8812: */  
                   8813: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8814:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8815:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8816:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8817:   printf("Model=%s\n\
                   8818: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8819: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8820: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8821:   fprintf(ficlog,"Model=%s\n\
                   8822: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8823: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8824: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8825:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8826:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8827:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8828:       Fixed[k]= 0;
                   8829:       Dummy[k]= 0;
1.225     brouard  8830:       ncoveff++;
1.232     brouard  8831:       ncovf++;
1.234     brouard  8832:       nsd++;
                   8833:       modell[k].maintype= FTYPE;
                   8834:       TvarsD[nsd]=Tvar[k];
                   8835:       TvarsDind[nsd]=k;
                   8836:       TvarF[ncovf]=Tvar[k];
                   8837:       TvarFind[ncovf]=k;
                   8838:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8839:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8840:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8841:       Fixed[k]= 0;
                   8842:       Dummy[k]= 0;
                   8843:       ncoveff++;
                   8844:       ncovf++;
                   8845:       modell[k].maintype= FTYPE;
                   8846:       TvarF[ncovf]=Tvar[k];
                   8847:       TvarFind[ncovf]=k;
1.230     brouard  8848:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8849:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8850:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8851:       Fixed[k]= 0;
                   8852:       Dummy[k]= 1;
1.230     brouard  8853:       nqfveff++;
1.234     brouard  8854:       modell[k].maintype= FTYPE;
                   8855:       modell[k].subtype= FQ;
                   8856:       nsq++;
                   8857:       TvarsQ[nsq]=Tvar[k];
                   8858:       TvarsQind[nsq]=k;
1.232     brouard  8859:       ncovf++;
1.234     brouard  8860:       TvarF[ncovf]=Tvar[k];
                   8861:       TvarFind[ncovf]=k;
1.231     brouard  8862:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8863:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8864:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8865:       Fixed[k]= 1;
                   8866:       Dummy[k]= 0;
1.225     brouard  8867:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8868:       modell[k].maintype= VTYPE;
                   8869:       modell[k].subtype= VD;
                   8870:       nsd++;
                   8871:       TvarsD[nsd]=Tvar[k];
                   8872:       TvarsDind[nsd]=k;
                   8873:       ncovv++; /* Only simple time varying variables */
                   8874:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8875:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8876:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8877:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8878:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8879:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8880:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8881:       Fixed[k]= 1;
                   8882:       Dummy[k]= 1;
                   8883:       nqtveff++;
                   8884:       modell[k].maintype= VTYPE;
                   8885:       modell[k].subtype= VQ;
                   8886:       ncovv++; /* Only simple time varying variables */
                   8887:       nsq++;
                   8888:       TvarsQ[nsq]=Tvar[k];
                   8889:       TvarsQind[nsq]=k;
                   8890:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8891:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8892:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8893:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8894:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8895:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8896:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8897:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8898:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8899:       ncova++;
                   8900:       TvarA[ncova]=Tvar[k];
                   8901:       TvarAind[ncova]=k;
1.231     brouard  8902:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8903:        Fixed[k]= 2;
                   8904:        Dummy[k]= 2;
                   8905:        modell[k].maintype= ATYPE;
                   8906:        modell[k].subtype= APFD;
                   8907:        /* ncoveff++; */
1.227     brouard  8908:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8909:        Fixed[k]= 2;
                   8910:        Dummy[k]= 3;
                   8911:        modell[k].maintype= ATYPE;
                   8912:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8913:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8914:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8915:        Fixed[k]= 3;
                   8916:        Dummy[k]= 2;
                   8917:        modell[k].maintype= ATYPE;
                   8918:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8919:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8920:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8921:        Fixed[k]= 3;
                   8922:        Dummy[k]= 3;
                   8923:        modell[k].maintype= ATYPE;
                   8924:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8925:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8926:       }
                   8927:     }else if (Typevar[k] == 2) {  /* product without age */
                   8928:       k1=Tposprod[k];
                   8929:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8930:        if(Tvard[k1][2] <=ncovcol){
                   8931:          Fixed[k]= 1;
                   8932:          Dummy[k]= 0;
                   8933:          modell[k].maintype= FTYPE;
                   8934:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8935:          ncovf++; /* Fixed variables without age */
                   8936:          TvarF[ncovf]=Tvar[k];
                   8937:          TvarFind[ncovf]=k;
                   8938:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8939:          Fixed[k]= 0;  /* or 2 ?*/
                   8940:          Dummy[k]= 1;
                   8941:          modell[k].maintype= FTYPE;
                   8942:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8943:          ncovf++; /* Varying variables without age */
                   8944:          TvarF[ncovf]=Tvar[k];
                   8945:          TvarFind[ncovf]=k;
                   8946:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8947:          Fixed[k]= 1;
                   8948:          Dummy[k]= 0;
                   8949:          modell[k].maintype= VTYPE;
                   8950:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8951:          ncovv++; /* Varying variables without age */
                   8952:          TvarV[ncovv]=Tvar[k];
                   8953:          TvarVind[ncovv]=k;
                   8954:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8955:          Fixed[k]= 1;
                   8956:          Dummy[k]= 1;
                   8957:          modell[k].maintype= VTYPE;
                   8958:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8959:          ncovv++; /* Varying variables without age */
                   8960:          TvarV[ncovv]=Tvar[k];
                   8961:          TvarVind[ncovv]=k;
                   8962:        }
1.227     brouard  8963:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8964:        if(Tvard[k1][2] <=ncovcol){
                   8965:          Fixed[k]= 0;  /* or 2 ?*/
                   8966:          Dummy[k]= 1;
                   8967:          modell[k].maintype= FTYPE;
                   8968:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8969:          ncovf++; /* Fixed variables without age */
                   8970:          TvarF[ncovf]=Tvar[k];
                   8971:          TvarFind[ncovf]=k;
                   8972:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8973:          Fixed[k]= 1;
                   8974:          Dummy[k]= 1;
                   8975:          modell[k].maintype= VTYPE;
                   8976:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8977:          ncovv++; /* Varying variables without age */
                   8978:          TvarV[ncovv]=Tvar[k];
                   8979:          TvarVind[ncovv]=k;
                   8980:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8981:          Fixed[k]= 1;
                   8982:          Dummy[k]= 1;
                   8983:          modell[k].maintype= VTYPE;
                   8984:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8985:          ncovv++; /* Varying variables without age */
                   8986:          TvarV[ncovv]=Tvar[k];
                   8987:          TvarVind[ncovv]=k;
                   8988:          ncovv++; /* Varying variables without age */
                   8989:          TvarV[ncovv]=Tvar[k];
                   8990:          TvarVind[ncovv]=k;
                   8991:        }
1.227     brouard  8992:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8993:        if(Tvard[k1][2] <=ncovcol){
                   8994:          Fixed[k]= 1;
                   8995:          Dummy[k]= 1;
                   8996:          modell[k].maintype= VTYPE;
                   8997:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   8998:          ncovv++; /* Varying variables without age */
                   8999:          TvarV[ncovv]=Tvar[k];
                   9000:          TvarVind[ncovv]=k;
                   9001:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9002:          Fixed[k]= 1;
                   9003:          Dummy[k]= 1;
                   9004:          modell[k].maintype= VTYPE;
                   9005:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9006:          ncovv++; /* Varying variables without age */
                   9007:          TvarV[ncovv]=Tvar[k];
                   9008:          TvarVind[ncovv]=k;
                   9009:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9010:          Fixed[k]= 1;
                   9011:          Dummy[k]= 0;
                   9012:          modell[k].maintype= VTYPE;
                   9013:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9014:          ncovv++; /* Varying variables without age */
                   9015:          TvarV[ncovv]=Tvar[k];
                   9016:          TvarVind[ncovv]=k;
                   9017:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9018:          Fixed[k]= 1;
                   9019:          Dummy[k]= 1;
                   9020:          modell[k].maintype= VTYPE;
                   9021:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9022:          ncovv++; /* Varying variables without age */
                   9023:          TvarV[ncovv]=Tvar[k];
                   9024:          TvarVind[ncovv]=k;
                   9025:        }
1.227     brouard  9026:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9027:        if(Tvard[k1][2] <=ncovcol){
                   9028:          Fixed[k]= 1;
                   9029:          Dummy[k]= 1;
                   9030:          modell[k].maintype= VTYPE;
                   9031:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9032:          ncovv++; /* Varying variables without age */
                   9033:          TvarV[ncovv]=Tvar[k];
                   9034:          TvarVind[ncovv]=k;
                   9035:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9036:          Fixed[k]= 1;
                   9037:          Dummy[k]= 1;
                   9038:          modell[k].maintype= VTYPE;
                   9039:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9040:          ncovv++; /* Varying variables without age */
                   9041:          TvarV[ncovv]=Tvar[k];
                   9042:          TvarVind[ncovv]=k;
                   9043:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9044:          Fixed[k]= 1;
                   9045:          Dummy[k]= 1;
                   9046:          modell[k].maintype= VTYPE;
                   9047:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9048:          ncovv++; /* Varying variables without age */
                   9049:          TvarV[ncovv]=Tvar[k];
                   9050:          TvarVind[ncovv]=k;
                   9051:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9052:          Fixed[k]= 1;
                   9053:          Dummy[k]= 1;
                   9054:          modell[k].maintype= VTYPE;
                   9055:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9056:          ncovv++; /* Varying variables without age */
                   9057:          TvarV[ncovv]=Tvar[k];
                   9058:          TvarVind[ncovv]=k;
                   9059:        }
1.227     brouard  9060:       }else{
1.240     brouard  9061:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9062:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9063:       } /*end k1*/
1.225     brouard  9064:     }else{
1.226     brouard  9065:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9066:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9067:     }
1.227     brouard  9068:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9069:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9070:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9071:   }
                   9072:   /* Searching for doublons in the model */
                   9073:   for(k1=1; k1<= cptcovt;k1++){
                   9074:     for(k2=1; k2 <k1;k2++){
                   9075:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9076:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9077:          if(Tvar[k1]==Tvar[k2]){
                   9078:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9079:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9080:            return(1);
                   9081:          }
                   9082:        }else if (Typevar[k1] ==2){
                   9083:          k3=Tposprod[k1];
                   9084:          k4=Tposprod[k2];
                   9085:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9086:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9087:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9088:            return(1);
                   9089:          }
                   9090:        }
1.227     brouard  9091:       }
                   9092:     }
1.225     brouard  9093:   }
                   9094:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9095:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9096:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9097:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9098:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9099:   /*endread:*/
1.225     brouard  9100:   printf("Exiting decodemodel: ");
                   9101:   return (1);
1.136     brouard  9102: }
                   9103: 
1.169     brouard  9104: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9105: {/* Check ages at death */
1.136     brouard  9106:   int i, m;
1.218     brouard  9107:   int firstone=0;
                   9108:   
1.136     brouard  9109:   for (i=1; i<=imx; i++) {
                   9110:     for(m=2; (m<= maxwav); m++) {
                   9111:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9112:        anint[m][i]=9999;
1.216     brouard  9113:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9114:          s[m][i]=-1;
1.136     brouard  9115:       }
                   9116:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9117:        *nberr = *nberr + 1;
1.218     brouard  9118:        if(firstone == 0){
                   9119:          firstone=1;
1.260     brouard  9120:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9121:        }
1.260     brouard  9122:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
                   9123:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9124:       }
                   9125:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9126:        (*nberr)++;
1.259     brouard  9127:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
                   9128:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
                   9129:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9130:       }
                   9131:     }
                   9132:   }
                   9133: 
                   9134:   for (i=1; i<=imx; i++)  {
                   9135:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9136:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9137:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9138:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9139:          if(agedc[i]>0){
                   9140:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9141:              agev[m][i]=agedc[i];
1.214     brouard  9142:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9143:            }else {
1.136     brouard  9144:              if ((int)andc[i]!=9999){
                   9145:                nbwarn++;
                   9146:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9147:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9148:                agev[m][i]=-1;
                   9149:              }
                   9150:            }
1.169     brouard  9151:          } /* agedc > 0 */
1.214     brouard  9152:        } /* end if */
1.136     brouard  9153:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9154:                                 years but with the precision of a month */
                   9155:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9156:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9157:            agev[m][i]=1;
                   9158:          else if(agev[m][i] < *agemin){ 
                   9159:            *agemin=agev[m][i];
                   9160:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9161:          }
                   9162:          else if(agev[m][i] >*agemax){
                   9163:            *agemax=agev[m][i];
1.156     brouard  9164:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9165:          }
                   9166:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9167:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9168:        } /* en if 9*/
1.136     brouard  9169:        else { /* =9 */
1.214     brouard  9170:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9171:          agev[m][i]=1;
                   9172:          s[m][i]=-1;
                   9173:        }
                   9174:       }
1.214     brouard  9175:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9176:        agev[m][i]=1;
1.214     brouard  9177:       else{
                   9178:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9179:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9180:        agev[m][i]=0;
                   9181:       }
                   9182:     } /* End for lastpass */
                   9183:   }
1.136     brouard  9184:     
                   9185:   for (i=1; i<=imx; i++)  {
                   9186:     for(m=firstpass; (m<=lastpass); m++){
                   9187:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9188:        (*nberr)++;
1.136     brouard  9189:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9190:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9191:        return 1;
                   9192:       }
                   9193:     }
                   9194:   }
                   9195: 
                   9196:   /*for (i=1; i<=imx; i++){
                   9197:   for (m=firstpass; (m<lastpass); m++){
                   9198:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9199: }
                   9200: 
                   9201: }*/
                   9202: 
                   9203: 
1.139     brouard  9204:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9205:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9206: 
                   9207:   return (0);
1.164     brouard  9208:  /* endread:*/
1.136     brouard  9209:     printf("Exiting calandcheckages: ");
                   9210:     return (1);
                   9211: }
                   9212: 
1.172     brouard  9213: #if defined(_MSC_VER)
                   9214: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9215: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9216: //#include "stdafx.h"
                   9217: //#include <stdio.h>
                   9218: //#include <tchar.h>
                   9219: //#include <windows.h>
                   9220: //#include <iostream>
                   9221: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9222: 
                   9223: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9224: 
                   9225: BOOL IsWow64()
                   9226: {
                   9227:        BOOL bIsWow64 = FALSE;
                   9228: 
                   9229:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9230:        //  (HANDLE, PBOOL);
                   9231: 
                   9232:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9233: 
                   9234:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9235:        const char funcName[] = "IsWow64Process";
                   9236:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9237:                GetProcAddress(module, funcName);
                   9238: 
                   9239:        if (NULL != fnIsWow64Process)
                   9240:        {
                   9241:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9242:                        &bIsWow64))
                   9243:                        //throw std::exception("Unknown error");
                   9244:                        printf("Unknown error\n");
                   9245:        }
                   9246:        return bIsWow64 != FALSE;
                   9247: }
                   9248: #endif
1.177     brouard  9249: 
1.191     brouard  9250: void syscompilerinfo(int logged)
1.167     brouard  9251:  {
                   9252:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9253:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9254:    /* /GS /W3 /Gy
                   9255:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9256:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9257:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9258:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9259:    */ 
                   9260:    /* 64 bits */
1.185     brouard  9261:    /*
                   9262:      /GS /W3 /Gy
                   9263:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9264:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9265:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9266:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9267:    /* Optimization are useless and O3 is slower than O2 */
                   9268:    /*
                   9269:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9270:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9271:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9272:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9273:    */
1.186     brouard  9274:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9275:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9276:       /PDB:"visual studio
                   9277:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9278:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9279:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9280:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9281:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9282:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9283:       uiAccess='false'"
                   9284:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9285:       /NOLOGO /TLBID:1
                   9286:    */
1.177     brouard  9287: #if defined __INTEL_COMPILER
1.178     brouard  9288: #if defined(__GNUC__)
                   9289:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9290: #endif
1.177     brouard  9291: #elif defined(__GNUC__) 
1.179     brouard  9292: #ifndef  __APPLE__
1.174     brouard  9293: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9294: #endif
1.177     brouard  9295:    struct utsname sysInfo;
1.178     brouard  9296:    int cross = CROSS;
                   9297:    if (cross){
                   9298:           printf("Cross-");
1.191     brouard  9299:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9300:    }
1.174     brouard  9301: #endif
                   9302: 
1.171     brouard  9303: #include <stdint.h>
1.178     brouard  9304: 
1.191     brouard  9305:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9306: #if defined(__clang__)
1.191     brouard  9307:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9308: #endif
                   9309: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9310:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9311: #endif
                   9312: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9313:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9314: #endif
                   9315: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9316:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9317: #endif
                   9318: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9319:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9320: #endif
                   9321: #if defined(_MSC_VER)
1.191     brouard  9322:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9323: #endif
                   9324: #if defined(__PGI)
1.191     brouard  9325:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9326: #endif
                   9327: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9328:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9329: #endif
1.191     brouard  9330:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9331:    
1.167     brouard  9332: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9333: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9334:     // Windows (x64 and x86)
1.191     brouard  9335:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9336: #elif __unix__ // all unices, not all compilers
                   9337:     // Unix
1.191     brouard  9338:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9339: #elif __linux__
                   9340:     // linux
1.191     brouard  9341:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9342: #elif __APPLE__
1.174     brouard  9343:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9344:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9345: #endif
                   9346: 
                   9347: /*  __MINGW32__          */
                   9348: /*  __CYGWIN__  */
                   9349: /* __MINGW64__  */
                   9350: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9351: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9352: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9353: /* _WIN64  // Defined for applications for Win64. */
                   9354: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9355: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9356: 
1.167     brouard  9357: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9358:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9359: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9360:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9361: #else
1.191     brouard  9362:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9363: #endif
                   9364: 
1.169     brouard  9365: #if defined(__GNUC__)
                   9366: # if defined(__GNUC_PATCHLEVEL__)
                   9367: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9368:                             + __GNUC_MINOR__ * 100 \
                   9369:                             + __GNUC_PATCHLEVEL__)
                   9370: # else
                   9371: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9372:                             + __GNUC_MINOR__ * 100)
                   9373: # endif
1.174     brouard  9374:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9375:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9376: 
                   9377:    if (uname(&sysInfo) != -1) {
                   9378:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9379:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9380:    }
                   9381:    else
                   9382:       perror("uname() error");
1.179     brouard  9383:    //#ifndef __INTEL_COMPILER 
                   9384: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9385:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9386:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9387: #endif
1.169     brouard  9388: #endif
1.172     brouard  9389: 
                   9390:    //   void main()
                   9391:    //   {
1.169     brouard  9392: #if defined(_MSC_VER)
1.174     brouard  9393:    if (IsWow64()){
1.191     brouard  9394:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9395:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9396:    }
                   9397:    else{
1.191     brouard  9398:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9399:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9400:    }
1.172     brouard  9401:    //     printf("\nPress Enter to continue...");
                   9402:    //     getchar();
                   9403:    //   }
                   9404: 
1.169     brouard  9405: #endif
                   9406:    
1.167     brouard  9407: 
1.219     brouard  9408: }
1.136     brouard  9409: 
1.219     brouard  9410: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9411:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9412:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9413:   /* double ftolpl = 1.e-10; */
1.180     brouard  9414:   double age, agebase, agelim;
1.203     brouard  9415:   double tot;
1.180     brouard  9416: 
1.202     brouard  9417:   strcpy(filerespl,"PL_");
                   9418:   strcat(filerespl,fileresu);
                   9419:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9420:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9421:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9422:   }
1.227     brouard  9423:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9424:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9425:   pstamp(ficrespl);
1.203     brouard  9426:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9427:   fprintf(ficrespl,"#Age ");
                   9428:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9429:   fprintf(ficrespl,"\n");
1.180     brouard  9430:   
1.219     brouard  9431:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9432: 
1.219     brouard  9433:   agebase=ageminpar;
                   9434:   agelim=agemaxpar;
1.180     brouard  9435: 
1.227     brouard  9436:   /* i1=pow(2,ncoveff); */
1.234     brouard  9437:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9438:   if (cptcovn < 1){i1=1;}
1.180     brouard  9439: 
1.238     brouard  9440:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9441:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9442:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9443:        continue;
1.235     brouard  9444: 
1.238     brouard  9445:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9446:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9447:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9448:       /* k=k+1; */
                   9449:       /* to clean */
                   9450:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9451:       fprintf(ficrespl,"#******");
                   9452:       printf("#******");
                   9453:       fprintf(ficlog,"#******");
                   9454:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9455:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9456:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9457:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9458:       }
                   9459:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9460:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9461:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9462:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9463:       }
                   9464:       fprintf(ficrespl,"******\n");
                   9465:       printf("******\n");
                   9466:       fprintf(ficlog,"******\n");
                   9467:       if(invalidvarcomb[k]){
                   9468:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9469:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9470:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9471:        continue;
                   9472:       }
1.219     brouard  9473: 
1.238     brouard  9474:       fprintf(ficrespl,"#Age ");
                   9475:       for(j=1;j<=cptcoveff;j++) {
                   9476:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9477:       }
                   9478:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9479:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9480:     
1.238     brouard  9481:       for (age=agebase; age<=agelim; age++){
                   9482:        /* for (age=agebase; age<=agebase; age++){ */
                   9483:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9484:        fprintf(ficrespl,"%.0f ",age );
                   9485:        for(j=1;j<=cptcoveff;j++)
                   9486:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9487:        tot=0.;
                   9488:        for(i=1; i<=nlstate;i++){
                   9489:          tot +=  prlim[i][i];
                   9490:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9491:        }
                   9492:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9493:       } /* Age */
                   9494:       /* was end of cptcod */
                   9495:     } /* cptcov */
                   9496:   } /* nres */
1.219     brouard  9497:   return 0;
1.180     brouard  9498: }
                   9499: 
1.218     brouard  9500: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9501:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9502:        
                   9503:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9504:    * at any age between ageminpar and agemaxpar
                   9505:         */
1.235     brouard  9506:   int i, j, k, i1, nres=0 ;
1.217     brouard  9507:   /* double ftolpl = 1.e-10; */
                   9508:   double age, agebase, agelim;
                   9509:   double tot;
1.218     brouard  9510:   /* double ***mobaverage; */
                   9511:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9512: 
                   9513:   strcpy(fileresplb,"PLB_");
                   9514:   strcat(fileresplb,fileresu);
                   9515:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9516:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9517:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9518:   }
                   9519:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9520:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9521:   pstamp(ficresplb);
                   9522:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9523:   fprintf(ficresplb,"#Age ");
                   9524:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9525:   fprintf(ficresplb,"\n");
                   9526:   
1.218     brouard  9527:   
                   9528:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9529:   
                   9530:   agebase=ageminpar;
                   9531:   agelim=agemaxpar;
                   9532:   
                   9533:   
1.227     brouard  9534:   i1=pow(2,cptcoveff);
1.218     brouard  9535:   if (cptcovn < 1){i1=1;}
1.227     brouard  9536:   
1.238     brouard  9537:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9538:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9539:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9540:        continue;
                   9541:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9542:       fprintf(ficresplb,"#******");
                   9543:       printf("#******");
                   9544:       fprintf(ficlog,"#******");
                   9545:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9546:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9547:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9548:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9549:       }
                   9550:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9551:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9552:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9553:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9554:       }
                   9555:       fprintf(ficresplb,"******\n");
                   9556:       printf("******\n");
                   9557:       fprintf(ficlog,"******\n");
                   9558:       if(invalidvarcomb[k]){
                   9559:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9560:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9561:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9562:        continue;
                   9563:       }
1.218     brouard  9564:     
1.238     brouard  9565:       fprintf(ficresplb,"#Age ");
                   9566:       for(j=1;j<=cptcoveff;j++) {
                   9567:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9568:       }
                   9569:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9570:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9571:     
                   9572:     
1.238     brouard  9573:       for (age=agebase; age<=agelim; age++){
                   9574:        /* for (age=agebase; age<=agebase; age++){ */
                   9575:        if(mobilavproj > 0){
                   9576:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9577:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9578:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9579:        }else if (mobilavproj == 0){
                   9580:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9581:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9582:          exit(1);
                   9583:        }else{
                   9584:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9585:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9586:        }
                   9587:        fprintf(ficresplb,"%.0f ",age );
                   9588:        for(j=1;j<=cptcoveff;j++)
                   9589:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9590:        tot=0.;
                   9591:        for(i=1; i<=nlstate;i++){
                   9592:          tot +=  bprlim[i][i];
                   9593:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9594:        }
                   9595:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9596:       } /* Age */
                   9597:       /* was end of cptcod */
1.255     brouard  9598:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9599:     } /* end of any combination */
                   9600:   } /* end of nres */  
1.218     brouard  9601:   /* hBijx(p, bage, fage); */
                   9602:   /* fclose(ficrespijb); */
                   9603:   
                   9604:   return 0;
1.217     brouard  9605: }
1.218     brouard  9606:  
1.180     brouard  9607: int hPijx(double *p, int bage, int fage){
                   9608:     /*------------- h Pij x at various ages ------------*/
                   9609: 
                   9610:   int stepsize;
                   9611:   int agelim;
                   9612:   int hstepm;
                   9613:   int nhstepm;
1.235     brouard  9614:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9615: 
                   9616:   double agedeb;
                   9617:   double ***p3mat;
                   9618: 
1.201     brouard  9619:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9620:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9621:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9622:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9623:     }
                   9624:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9625:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9626:   
                   9627:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9628:     /*if (stepm<=24) stepsize=2;*/
                   9629: 
                   9630:     agelim=AGESUP;
                   9631:     hstepm=stepsize*YEARM; /* Every year of age */
                   9632:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9633:                
1.180     brouard  9634:     /* hstepm=1;   aff par mois*/
                   9635:     pstamp(ficrespij);
                   9636:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9637:     i1= pow(2,cptcoveff);
1.218     brouard  9638:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9639:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9640:                /*      k=k+1;  */
1.235     brouard  9641:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9642:     for(k=1; k<=i1;k++){
1.253     brouard  9643:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9644:        continue;
1.183     brouard  9645:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9646:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9647:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9648:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9649:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9650:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9651:       }
1.183     brouard  9652:       fprintf(ficrespij,"******\n");
                   9653:       
                   9654:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9655:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9656:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9657:        
                   9658:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9659:        
1.183     brouard  9660:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9661:        oldm=oldms;savm=savms;
1.235     brouard  9662:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9663:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9664:        for(i=1; i<=nlstate;i++)
                   9665:          for(j=1; j<=nlstate+ndeath;j++)
                   9666:            fprintf(ficrespij," %1d-%1d",i,j);
                   9667:        fprintf(ficrespij,"\n");
                   9668:        for (h=0; h<=nhstepm; h++){
                   9669:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9670:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9671:          for(i=1; i<=nlstate;i++)
                   9672:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9673:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9674:          fprintf(ficrespij,"\n");
                   9675:        }
1.183     brouard  9676:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9677:        fprintf(ficrespij,"\n");
                   9678:       }
1.180     brouard  9679:       /*}*/
                   9680:     }
1.218     brouard  9681:     return 0;
1.180     brouard  9682: }
1.218     brouard  9683:  
                   9684:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9685:     /*------------- h Bij x at various ages ------------*/
                   9686: 
                   9687:   int stepsize;
1.218     brouard  9688:   /* int agelim; */
                   9689:        int ageminl;
1.217     brouard  9690:   int hstepm;
                   9691:   int nhstepm;
1.238     brouard  9692:   int h, i, i1, j, k, nres;
1.218     brouard  9693:        
1.217     brouard  9694:   double agedeb;
                   9695:   double ***p3mat;
1.218     brouard  9696:        
                   9697:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9698:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9699:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9700:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9701:   }
                   9702:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9703:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9704:   
                   9705:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9706:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9707:   
1.218     brouard  9708:   /* agelim=AGESUP; */
                   9709:   ageminl=30;
                   9710:   hstepm=stepsize*YEARM; /* Every year of age */
                   9711:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9712:   
                   9713:   /* hstepm=1;   aff par mois*/
                   9714:   pstamp(ficrespijb);
1.255     brouard  9715:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9716:   i1= pow(2,cptcoveff);
1.218     brouard  9717:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9718:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9719:   /*   k=k+1;  */
1.238     brouard  9720:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9721:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9722:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9723:        continue;
                   9724:       fprintf(ficrespijb,"\n#****** ");
                   9725:       for(j=1;j<=cptcoveff;j++)
                   9726:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9727:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9728:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9729:       }
                   9730:       fprintf(ficrespijb,"******\n");
                   9731:       if(invalidvarcomb[k]){
                   9732:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9733:        continue;
                   9734:       }
                   9735:       
                   9736:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9737:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9738:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9739:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9740:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9741:        
                   9742:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9743:        
                   9744:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9745:        /* oldm=oldms;savm=savms; */
                   9746:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9747:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9748:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  9749:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9750:        for(i=1; i<=nlstate;i++)
                   9751:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9752:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9753:        fprintf(ficrespijb,"\n");
1.238     brouard  9754:        for (h=0; h<=nhstepm; h++){
                   9755:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9756:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9757:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9758:          for(i=1; i<=nlstate;i++)
                   9759:            for(j=1; j<=nlstate+ndeath;j++)
                   9760:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9761:          fprintf(ficrespijb,"\n");
                   9762:        }
                   9763:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9764:        fprintf(ficrespijb,"\n");
                   9765:       } /* end age deb */
                   9766:     } /* end combination */
                   9767:   } /* end nres */
1.218     brouard  9768:   return 0;
                   9769:  } /*  hBijx */
1.217     brouard  9770: 
1.180     brouard  9771: 
1.136     brouard  9772: /***********************************************/
                   9773: /**************** Main Program *****************/
                   9774: /***********************************************/
                   9775: 
                   9776: int main(int argc, char *argv[])
                   9777: {
                   9778: #ifdef GSL
                   9779:   const gsl_multimin_fminimizer_type *T;
                   9780:   size_t iteri = 0, it;
                   9781:   int rval = GSL_CONTINUE;
                   9782:   int status = GSL_SUCCESS;
                   9783:   double ssval;
                   9784: #endif
                   9785:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9786:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9787:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9788:   int jj, ll, li, lj, lk;
1.136     brouard  9789:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9790:   int num_filled;
1.136     brouard  9791:   int itimes;
                   9792:   int NDIM=2;
                   9793:   int vpopbased=0;
1.235     brouard  9794:   int nres=0;
1.258     brouard  9795:   int endishere=0;
1.136     brouard  9796: 
1.164     brouard  9797:   char ca[32], cb[32];
1.136     brouard  9798:   /*  FILE *fichtm; *//* Html File */
                   9799:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9800:   struct stat info;
1.191     brouard  9801:   double agedeb=0.;
1.194     brouard  9802: 
                   9803:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9804:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9805: 
1.165     brouard  9806:   double fret;
1.191     brouard  9807:   double dum=0.; /* Dummy variable */
1.136     brouard  9808:   double ***p3mat;
1.218     brouard  9809:   /* double ***mobaverage; */
1.164     brouard  9810: 
                   9811:   char line[MAXLINE];
1.197     brouard  9812:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9813: 
1.234     brouard  9814:   char  modeltemp[MAXLINE];
1.230     brouard  9815:   char resultline[MAXLINE];
                   9816:   
1.136     brouard  9817:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9818:   char *tok, *val; /* pathtot */
1.136     brouard  9819:   int firstobs=1, lastobs=10;
1.195     brouard  9820:   int c,  h , cpt, c2;
1.191     brouard  9821:   int jl=0;
                   9822:   int i1, j1, jk, stepsize=0;
1.194     brouard  9823:   int count=0;
                   9824: 
1.164     brouard  9825:   int *tab; 
1.136     brouard  9826:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9827:   int backcast=0;
1.136     brouard  9828:   int mobilav=0,popforecast=0;
1.191     brouard  9829:   int hstepm=0, nhstepm=0;
1.136     brouard  9830:   int agemortsup;
                   9831:   float  sumlpop=0.;
                   9832:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9833:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9834: 
1.191     brouard  9835:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9836:   double ftolpl=FTOL;
                   9837:   double **prlim;
1.217     brouard  9838:   double **bprlim;
1.136     brouard  9839:   double ***param; /* Matrix of parameters */
1.251     brouard  9840:   double ***paramstart; /* Matrix of starting parameter values */
                   9841:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9842:   double **matcov; /* Matrix of covariance */
1.203     brouard  9843:   double **hess; /* Hessian matrix */
1.136     brouard  9844:   double ***delti3; /* Scale */
                   9845:   double *delti; /* Scale */
                   9846:   double ***eij, ***vareij;
                   9847:   double **varpl; /* Variances of prevalence limits by age */
                   9848:   double *epj, vepp;
1.164     brouard  9849: 
1.136     brouard  9850:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9851:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9852: 
1.136     brouard  9853:   double **ximort;
1.145     brouard  9854:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9855:   int *dcwave;
                   9856: 
1.164     brouard  9857:   char z[1]="c";
1.136     brouard  9858: 
                   9859:   /*char  *strt;*/
                   9860:   char strtend[80];
1.126     brouard  9861: 
1.164     brouard  9862: 
1.126     brouard  9863: /*   setlocale (LC_ALL, ""); */
                   9864: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9865: /*   textdomain (PACKAGE); */
                   9866: /*   setlocale (LC_CTYPE, ""); */
                   9867: /*   setlocale (LC_MESSAGES, ""); */
                   9868: 
                   9869:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9870:   rstart_time = time(NULL);  
                   9871:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9872:   start_time = *localtime(&rstart_time);
1.126     brouard  9873:   curr_time=start_time;
1.157     brouard  9874:   /*tml = *localtime(&start_time.tm_sec);*/
                   9875:   /* strcpy(strstart,asctime(&tml)); */
                   9876:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9877: 
                   9878: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9879: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9880: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9881: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9882: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9883: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9884: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9885: /*   strt=asctime(&tmg); */
                   9886: /*   printf("Time(after) =%s",strstart);  */
                   9887: /*  (void) time (&time_value);
                   9888: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9889: *  tm = *localtime(&time_value);
                   9890: *  strstart=asctime(&tm);
                   9891: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9892: */
                   9893: 
                   9894:   nberr=0; /* Number of errors and warnings */
                   9895:   nbwarn=0;
1.184     brouard  9896: #ifdef WIN32
                   9897:   _getcwd(pathcd, size);
                   9898: #else
1.126     brouard  9899:   getcwd(pathcd, size);
1.184     brouard  9900: #endif
1.191     brouard  9901:   syscompilerinfo(0);
1.196     brouard  9902:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9903:   if(argc <=1){
                   9904:     printf("\nEnter the parameter file name: ");
1.205     brouard  9905:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9906:       printf("ERROR Empty parameter file name\n");
                   9907:       goto end;
                   9908:     }
1.126     brouard  9909:     i=strlen(pathr);
                   9910:     if(pathr[i-1]=='\n')
                   9911:       pathr[i-1]='\0';
1.156     brouard  9912:     i=strlen(pathr);
1.205     brouard  9913:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9914:       pathr[i-1]='\0';
1.205     brouard  9915:     }
                   9916:     i=strlen(pathr);
                   9917:     if( i==0 ){
                   9918:       printf("ERROR Empty parameter file name\n");
                   9919:       goto end;
                   9920:     }
                   9921:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9922:       printf("Pathr |%s|\n",pathr);
                   9923:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9924:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9925:       strcpy (pathtot, val);
                   9926:       if(pathr[0] == '\0') break; /* Dirty */
                   9927:     }
                   9928:   }
                   9929:   else{
                   9930:     strcpy(pathtot,argv[1]);
                   9931:   }
                   9932:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9933:   /*cygwin_split_path(pathtot,path,optionfile);
                   9934:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9935:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9936: 
                   9937:   /* Split argv[0], imach program to get pathimach */
                   9938:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9939:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9940:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9941:  /*   strcpy(pathimach,argv[0]); */
                   9942:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9943:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9944:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9945: #ifdef WIN32
                   9946:   _chdir(path); /* Can be a relative path */
                   9947:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9948: #else
1.126     brouard  9949:   chdir(path); /* Can be a relative path */
1.184     brouard  9950:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9951: #endif
                   9952:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9953:   strcpy(command,"mkdir ");
                   9954:   strcat(command,optionfilefiname);
                   9955:   if((outcmd=system(command)) != 0){
1.169     brouard  9956:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9957:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9958:     /* fclose(ficlog); */
                   9959: /*     exit(1); */
                   9960:   }
                   9961: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9962: /*     perror("mkdir"); */
                   9963: /*   } */
                   9964: 
                   9965:   /*-------- arguments in the command line --------*/
                   9966: 
1.186     brouard  9967:   /* Main Log file */
1.126     brouard  9968:   strcat(filelog, optionfilefiname);
                   9969:   strcat(filelog,".log");    /* */
                   9970:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9971:     printf("Problem with logfile %s\n",filelog);
                   9972:     goto end;
                   9973:   }
                   9974:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9975:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9976:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9977:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9978:  path=%s \n\
                   9979:  optionfile=%s\n\
                   9980:  optionfilext=%s\n\
1.156     brouard  9981:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9982: 
1.197     brouard  9983:   syscompilerinfo(1);
1.167     brouard  9984: 
1.126     brouard  9985:   printf("Local time (at start):%s",strstart);
                   9986:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9987:   fflush(ficlog);
                   9988: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9989: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9990: 
                   9991:   /* */
                   9992:   strcpy(fileres,"r");
                   9993:   strcat(fileres, optionfilefiname);
1.201     brouard  9994:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  9995:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  9996:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  9997: 
1.186     brouard  9998:   /* Main ---------arguments file --------*/
1.126     brouard  9999: 
                   10000:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10001:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10002:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10003:     fflush(ficlog);
1.149     brouard  10004:     /* goto end; */
                   10005:     exit(70); 
1.126     brouard  10006:   }
                   10007: 
                   10008: 
                   10009: 
                   10010:   strcpy(filereso,"o");
1.201     brouard  10011:   strcat(filereso,fileresu);
1.126     brouard  10012:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10013:     printf("Problem with Output resultfile: %s\n", filereso);
                   10014:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10015:     fflush(ficlog);
                   10016:     goto end;
                   10017:   }
                   10018: 
                   10019:   /* Reads comments: lines beginning with '#' */
                   10020:   numlinepar=0;
1.197     brouard  10021: 
                   10022:     /* First parameter line */
                   10023:   while(fgets(line, MAXLINE, ficpar)) {
                   10024:     /* If line starts with a # it is a comment */
                   10025:     if (line[0] == '#') {
                   10026:       numlinepar++;
                   10027:       fputs(line,stdout);
                   10028:       fputs(line,ficparo);
                   10029:       fputs(line,ficlog);
                   10030:       continue;
                   10031:     }else
                   10032:       break;
                   10033:   }
                   10034:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10035:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10036:     if (num_filled != 5) {
                   10037:       printf("Should be 5 parameters\n");
                   10038:     }
1.126     brouard  10039:     numlinepar++;
1.197     brouard  10040:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10041:   }
                   10042:   /* Second parameter line */
                   10043:   while(fgets(line, MAXLINE, ficpar)) {
                   10044:     /* If line starts with a # it is a comment */
                   10045:     if (line[0] == '#') {
                   10046:       numlinepar++;
                   10047:       fputs(line,stdout);
                   10048:       fputs(line,ficparo);
                   10049:       fputs(line,ficlog);
                   10050:       continue;
                   10051:     }else
                   10052:       break;
                   10053:   }
1.223     brouard  10054:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10055:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10056:     if (num_filled != 11) {
                   10057:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10058:       printf("but line=%s\n",line);
1.197     brouard  10059:     }
1.223     brouard  10060:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10061:   }
1.203     brouard  10062:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10063:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10064:   /* Third parameter line */
                   10065:   while(fgets(line, MAXLINE, ficpar)) {
                   10066:     /* If line starts with a # it is a comment */
                   10067:     if (line[0] == '#') {
                   10068:       numlinepar++;
                   10069:       fputs(line,stdout);
                   10070:       fputs(line,ficparo);
                   10071:       fputs(line,ficlog);
                   10072:       continue;
                   10073:     }else
                   10074:       break;
                   10075:   }
1.201     brouard  10076:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
                   10077:     if (num_filled == 0)
                   10078:             model[0]='\0';
                   10079:     else if (num_filled != 1){
1.197     brouard  10080:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10081:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10082:       model[0]='\0';
                   10083:       goto end;
                   10084:     }
                   10085:     else{
                   10086:       if (model[0]=='+'){
                   10087:        for(i=1; i<=strlen(model);i++)
                   10088:          modeltemp[i-1]=model[i];
1.201     brouard  10089:        strcpy(model,modeltemp); 
1.197     brouard  10090:       }
                   10091:     }
1.199     brouard  10092:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10093:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10094:   }
                   10095:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10096:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10097:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10098:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10099:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10100:   fflush(ficlog);
1.190     brouard  10101:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10102:   if(model[0]=='#'){
1.187     brouard  10103:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10104:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10105:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10106:     if(mle != -1){
                   10107:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10108:       exit(1);
                   10109:     }
                   10110:   }
1.126     brouard  10111:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10112:     ungetc(c,ficpar);
                   10113:     fgets(line, MAXLINE, ficpar);
                   10114:     numlinepar++;
1.195     brouard  10115:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10116:       z[0]=line[1];
                   10117:     }
                   10118:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10119:     fputs(line, stdout);
                   10120:     //puts(line);
1.126     brouard  10121:     fputs(line,ficparo);
                   10122:     fputs(line,ficlog);
                   10123:   }
                   10124:   ungetc(c,ficpar);
                   10125: 
                   10126:    
1.145     brouard  10127:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10128:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10129:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10130:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10131:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10132:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10133:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10134:   */
                   10135:   if (strlen(model)>1) 
1.187     brouard  10136:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10137:   else
1.187     brouard  10138:     ncovmodel=2; /* Constant and age */
1.133     brouard  10139:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10140:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10141:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10142:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10143:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10144:     fflush(stdout);
                   10145:     fclose (ficlog);
                   10146:     goto end;
                   10147:   }
1.126     brouard  10148:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10149:   delti=delti3[1][1];
                   10150:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10151:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10152: /* We could also provide initial parameters values giving by simple logistic regression 
                   10153:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10154:       /* for(i=1;i<nlstate;i++){ */
                   10155:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10156:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10157:       /* } */
1.126     brouard  10158:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10159:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10160:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10161:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10162:     fclose (ficparo);
                   10163:     fclose (ficlog);
                   10164:     goto end;
                   10165:     exit(0);
1.220     brouard  10166:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10167:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10168:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10169:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10170:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10171:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10172:     hess=matrix(1,npar,1,npar);
1.220     brouard  10173:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10174:     /* Read guessed parameters */
1.126     brouard  10175:     /* Reads comments: lines beginning with '#' */
                   10176:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10177:       ungetc(c,ficpar);
                   10178:       fgets(line, MAXLINE, ficpar);
                   10179:       numlinepar++;
1.141     brouard  10180:       fputs(line,stdout);
1.126     brouard  10181:       fputs(line,ficparo);
                   10182:       fputs(line,ficlog);
                   10183:     }
                   10184:     ungetc(c,ficpar);
                   10185:     
                   10186:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10187:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10188:     for(i=1; i <=nlstate; i++){
1.234     brouard  10189:       j=0;
1.126     brouard  10190:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10191:        if(jj==i) continue;
                   10192:        j++;
                   10193:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10194:        if ((i1 != i) || (j1 != jj)){
                   10195:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10196: It might be a problem of design; if ncovcol and the model are correct\n \
                   10197: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10198:          exit(1);
                   10199:        }
                   10200:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10201:        if(mle==1)
                   10202:          printf("%1d%1d",i,jj);
                   10203:        fprintf(ficlog,"%1d%1d",i,jj);
                   10204:        for(k=1; k<=ncovmodel;k++){
                   10205:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10206:          if(mle==1){
                   10207:            printf(" %lf",param[i][j][k]);
                   10208:            fprintf(ficlog," %lf",param[i][j][k]);
                   10209:          }
                   10210:          else
                   10211:            fprintf(ficlog," %lf",param[i][j][k]);
                   10212:          fprintf(ficparo," %lf",param[i][j][k]);
                   10213:        }
                   10214:        fscanf(ficpar,"\n");
                   10215:        numlinepar++;
                   10216:        if(mle==1)
                   10217:          printf("\n");
                   10218:        fprintf(ficlog,"\n");
                   10219:        fprintf(ficparo,"\n");
1.126     brouard  10220:       }
                   10221:     }  
                   10222:     fflush(ficlog);
1.234     brouard  10223:     
1.251     brouard  10224:     /* Reads parameters values */
1.126     brouard  10225:     p=param[1][1];
1.251     brouard  10226:     pstart=paramstart[1][1];
1.126     brouard  10227:     
                   10228:     /* Reads comments: lines beginning with '#' */
                   10229:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10230:       ungetc(c,ficpar);
                   10231:       fgets(line, MAXLINE, ficpar);
                   10232:       numlinepar++;
1.141     brouard  10233:       fputs(line,stdout);
1.126     brouard  10234:       fputs(line,ficparo);
                   10235:       fputs(line,ficlog);
                   10236:     }
                   10237:     ungetc(c,ficpar);
                   10238: 
                   10239:     for(i=1; i <=nlstate; i++){
                   10240:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10241:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10242:        if ( (i1-i) * (j1-j) != 0){
                   10243:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10244:          exit(1);
                   10245:        }
                   10246:        printf("%1d%1d",i,j);
                   10247:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10248:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10249:        for(k=1; k<=ncovmodel;k++){
                   10250:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10251:          printf(" %le",delti3[i][j][k]);
                   10252:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10253:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10254:        }
                   10255:        fscanf(ficpar,"\n");
                   10256:        numlinepar++;
                   10257:        printf("\n");
                   10258:        fprintf(ficparo,"\n");
                   10259:        fprintf(ficlog,"\n");
1.126     brouard  10260:       }
                   10261:     }
                   10262:     fflush(ficlog);
1.234     brouard  10263:     
1.145     brouard  10264:     /* Reads covariance matrix */
1.126     brouard  10265:     delti=delti3[1][1];
1.220     brouard  10266:                
                   10267:                
1.126     brouard  10268:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10269:                
1.126     brouard  10270:     /* Reads comments: lines beginning with '#' */
                   10271:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10272:       ungetc(c,ficpar);
                   10273:       fgets(line, MAXLINE, ficpar);
                   10274:       numlinepar++;
1.141     brouard  10275:       fputs(line,stdout);
1.126     brouard  10276:       fputs(line,ficparo);
                   10277:       fputs(line,ficlog);
                   10278:     }
                   10279:     ungetc(c,ficpar);
1.220     brouard  10280:                
1.126     brouard  10281:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10282:     hess=matrix(1,npar,1,npar);
1.131     brouard  10283:     for(i=1; i <=npar; i++)
                   10284:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10285:                
1.194     brouard  10286:     /* Scans npar lines */
1.126     brouard  10287:     for(i=1; i <=npar; i++){
1.226     brouard  10288:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10289:       if(count != 3){
1.226     brouard  10290:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10291: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10292: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10293:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10294: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10295: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10296:        exit(1);
1.220     brouard  10297:       }else{
1.226     brouard  10298:        if(mle==1)
                   10299:          printf("%1d%1d%d",i1,j1,jk);
                   10300:       }
                   10301:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10302:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10303:       for(j=1; j <=i; j++){
1.226     brouard  10304:        fscanf(ficpar," %le",&matcov[i][j]);
                   10305:        if(mle==1){
                   10306:          printf(" %.5le",matcov[i][j]);
                   10307:        }
                   10308:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10309:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10310:       }
                   10311:       fscanf(ficpar,"\n");
                   10312:       numlinepar++;
                   10313:       if(mle==1)
1.220     brouard  10314:                                printf("\n");
1.126     brouard  10315:       fprintf(ficlog,"\n");
                   10316:       fprintf(ficparo,"\n");
                   10317:     }
1.194     brouard  10318:     /* End of read covariance matrix npar lines */
1.126     brouard  10319:     for(i=1; i <=npar; i++)
                   10320:       for(j=i+1;j<=npar;j++)
1.226     brouard  10321:        matcov[i][j]=matcov[j][i];
1.126     brouard  10322:     
                   10323:     if(mle==1)
                   10324:       printf("\n");
                   10325:     fprintf(ficlog,"\n");
                   10326:     
                   10327:     fflush(ficlog);
                   10328:     
                   10329:     /*-------- Rewriting parameter file ----------*/
                   10330:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10331:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10332:     strcat(rfileres,".");    /* */
                   10333:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10334:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10335:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10336:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10337:     }
                   10338:     fprintf(ficres,"#%s\n",version);
                   10339:   }    /* End of mle != -3 */
1.218     brouard  10340:   
1.186     brouard  10341:   /*  Main data
                   10342:    */
1.126     brouard  10343:   n= lastobs;
                   10344:   num=lvector(1,n);
                   10345:   moisnais=vector(1,n);
                   10346:   annais=vector(1,n);
                   10347:   moisdc=vector(1,n);
                   10348:   andc=vector(1,n);
1.220     brouard  10349:   weight=vector(1,n);
1.126     brouard  10350:   agedc=vector(1,n);
                   10351:   cod=ivector(1,n);
1.220     brouard  10352:   for(i=1;i<=n;i++){
1.234     brouard  10353:     num[i]=0;
                   10354:     moisnais[i]=0;
                   10355:     annais[i]=0;
                   10356:     moisdc[i]=0;
                   10357:     andc[i]=0;
                   10358:     agedc[i]=0;
                   10359:     cod[i]=0;
                   10360:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10361:   }
1.126     brouard  10362:   mint=matrix(1,maxwav,1,n);
                   10363:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10364:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10365:   tab=ivector(1,NCOVMAX);
1.144     brouard  10366:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10367:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10368: 
1.136     brouard  10369:   /* Reads data from file datafile */
                   10370:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10371:     goto end;
                   10372: 
                   10373:   /* Calculation of the number of parameters from char model */
1.234     brouard  10374:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10375:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10376:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10377:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10378:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10379:   */
                   10380:   
                   10381:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10382:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10383:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10384:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10385:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10386:   TvarF=ivector(1,NCOVMAX); /*  */
                   10387:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10388:   TvarV=ivector(1,NCOVMAX); /*  */
                   10389:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10390:   TvarA=ivector(1,NCOVMAX); /*  */
                   10391:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10392:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10393:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10394:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10395:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10396:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10397:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10398:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10399:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10400: 
1.230     brouard  10401:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10402:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10403:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10404:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10405:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10406:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10407:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10408:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10409:   */
                   10410:   /* For model-covariate k tells which data-covariate to use but
                   10411:     because this model-covariate is a construction we invent a new column
                   10412:     ncovcol + k1
                   10413:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10414:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10415:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10416:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10417:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10418:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10419:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10420:   */
1.145     brouard  10421:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10422:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10423:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10424:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10425:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10426:                         4 covariates (3 plus signs)
                   10427:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10428:                      */  
1.230     brouard  10429:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10430:                                * individual dummy, fixed or varying:
                   10431:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10432:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10433:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10434:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10435:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10436:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10437:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10438:                                * individual quantitative, fixed or varying:
                   10439:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10440:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10441:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10442: /* Main decodemodel */
                   10443: 
1.187     brouard  10444: 
1.223     brouard  10445:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10446:     goto end;
                   10447: 
1.137     brouard  10448:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10449:     nbwarn++;
                   10450:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10451:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10452:   }
1.136     brouard  10453:     /*  if(mle==1){*/
1.137     brouard  10454:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10455:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10456:   }
                   10457: 
                   10458:     /*-calculation of age at interview from date of interview and age at death -*/
                   10459:   agev=matrix(1,maxwav,1,imx);
                   10460: 
                   10461:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10462:     goto end;
                   10463: 
1.126     brouard  10464: 
1.136     brouard  10465:   agegomp=(int)agemin;
                   10466:   free_vector(moisnais,1,n);
                   10467:   free_vector(annais,1,n);
1.126     brouard  10468:   /* free_matrix(mint,1,maxwav,1,n);
                   10469:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10470:   /* free_vector(moisdc,1,n); */
                   10471:   /* free_vector(andc,1,n); */
1.145     brouard  10472:   /* */
                   10473:   
1.126     brouard  10474:   wav=ivector(1,imx);
1.214     brouard  10475:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10476:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10477:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10478:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10479:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10480:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10481:    
                   10482:   /* Concatenates waves */
1.214     brouard  10483:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10484:      Death is a valid wave (if date is known).
                   10485:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10486:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10487:      and mw[mi+1][i]. dh depends on stepm.
                   10488:   */
                   10489: 
1.126     brouard  10490:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10491:   /* Concatenates waves */
1.145     brouard  10492:  
1.215     brouard  10493:   free_vector(moisdc,1,n);
                   10494:   free_vector(andc,1,n);
                   10495: 
1.126     brouard  10496:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10497:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10498:   ncodemax[1]=1;
1.145     brouard  10499:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10500:   cptcoveff=0;
1.220     brouard  10501:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10502:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10503:   }
                   10504:   
                   10505:   ncovcombmax=pow(2,cptcoveff);
                   10506:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10507:   for(i=1;i<ncovcombmax;i++)
                   10508:     invalidvarcomb[i]=0;
                   10509:   
1.211     brouard  10510:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10511:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10512:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10513:   
1.200     brouard  10514:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10515:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10516:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10517:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10518:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10519:    * (currently 0 or 1) in the data.
                   10520:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10521:    * corresponding modality (h,j).
                   10522:    */
                   10523: 
1.145     brouard  10524:   h=0;
                   10525:   /*if (cptcovn > 0) */
1.126     brouard  10526:   m=pow(2,cptcoveff);
                   10527:  
1.144     brouard  10528:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10529:           * For k=4 covariates, h goes from 1 to m=2**k
                   10530:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10531:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10532:           *     h\k   1     2     3     4
1.143     brouard  10533:           *______________________________  
                   10534:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10535:           *     2     2     1     1     1
                   10536:           *     3 i=2 1     2     1     1
                   10537:           *     4     2     2     1     1
                   10538:           *     5 i=3 1 i=2 1     2     1
                   10539:           *     6     2     1     2     1
                   10540:           *     7 i=4 1     2     2     1
                   10541:           *     8     2     2     2     1
1.197     brouard  10542:           *     9 i=5 1 i=3 1 i=2 1     2
                   10543:           *    10     2     1     1     2
                   10544:           *    11 i=6 1     2     1     2
                   10545:           *    12     2     2     1     2
                   10546:           *    13 i=7 1 i=4 1     2     2    
                   10547:           *    14     2     1     2     2
                   10548:           *    15 i=8 1     2     2     2
                   10549:           *    16     2     2     2     2
1.143     brouard  10550:           */
1.212     brouard  10551:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10552:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10553:      * and the value of each covariate?
                   10554:      * V1=1, V2=1, V3=2, V4=1 ?
                   10555:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10556:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10557:      * In order to get the real value in the data, we use nbcode
                   10558:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10559:      * We are keeping this crazy system in order to be able (in the future?) 
                   10560:      * to have more than 2 values (0 or 1) for a covariate.
                   10561:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10562:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10563:      *              bbbbbbbb
                   10564:      *              76543210     
                   10565:      *   h-1        00000101 (6-1=5)
1.219     brouard  10566:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10567:      *           &
                   10568:      *     1        00000001 (1)
1.219     brouard  10569:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10570:      *          +1= 00000001 =1 
1.211     brouard  10571:      *
                   10572:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10573:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10574:      *    >>k'            11
                   10575:      *          &   00000001
                   10576:      *            = 00000001
                   10577:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10578:      * Reverse h=6 and m=16?
                   10579:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10580:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10581:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10582:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10583:      * V3=decodtabm(14,3,2**4)=2
                   10584:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10585:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10586:      *          &1 000000001
                   10587:      *           = 000000001
                   10588:      *         +1= 000000010 =2
                   10589:      *                  2211
                   10590:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10591:      *                  V3=2
1.220     brouard  10592:                 * codtabm and decodtabm are identical
1.211     brouard  10593:      */
                   10594: 
1.145     brouard  10595: 
                   10596:  free_ivector(Ndum,-1,NCOVMAX);
                   10597: 
                   10598: 
1.126     brouard  10599:     
1.186     brouard  10600:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10601:   strcpy(optionfilegnuplot,optionfilefiname);
                   10602:   if(mle==-3)
1.201     brouard  10603:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10604:   strcat(optionfilegnuplot,".gp");
                   10605: 
                   10606:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10607:     printf("Problem with file %s",optionfilegnuplot);
                   10608:   }
                   10609:   else{
1.204     brouard  10610:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10611:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10612:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10613:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10614:   }
                   10615:   /*  fclose(ficgp);*/
1.186     brouard  10616: 
                   10617: 
                   10618:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10619: 
                   10620:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10621:   if(mle==-3)
1.201     brouard  10622:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10623:   strcat(optionfilehtm,".htm");
                   10624:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10625:     printf("Problem with %s \n",optionfilehtm);
                   10626:     exit(0);
1.126     brouard  10627:   }
                   10628: 
                   10629:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10630:   strcat(optionfilehtmcov,"-cov.htm");
                   10631:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10632:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10633:   }
                   10634:   else{
                   10635:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10636: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10637: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10638:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10639:   }
                   10640: 
1.213     brouard  10641:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10642: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10643: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10644: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10645: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10646: \n\
                   10647: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10648:  <ul><li><h4>Parameter files</h4>\n\
                   10649:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10650:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10651:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10652:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10653:  - Date and time at start: %s</ul>\n",\
                   10654:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10655:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10656:          fileres,fileres,\
                   10657:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10658:   fflush(fichtm);
                   10659: 
                   10660:   strcpy(pathr,path);
                   10661:   strcat(pathr,optionfilefiname);
1.184     brouard  10662: #ifdef WIN32
                   10663:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10664: #else
1.126     brouard  10665:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10666: #endif
                   10667:          
1.126     brouard  10668:   
1.220     brouard  10669:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10670:                 and for any valid combination of covariates
1.126     brouard  10671:      and prints on file fileres'p'. */
1.251     brouard  10672:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10673:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10674: 
                   10675:   fprintf(fichtm,"\n");
                   10676:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10677: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10678: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10679:          imx,agemin,agemax,jmin,jmax,jmean);
                   10680:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10681:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10682:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10683:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10684:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10685: 
1.126     brouard  10686:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10687:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10688:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10689: 
                   10690:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10691:   /* For mortality only */
1.126     brouard  10692:   if (mle==-3){
1.136     brouard  10693:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10694:     for(i=1;i<=NDIM;i++)
                   10695:       for(j=1;j<=NDIM;j++)
                   10696:        ximort[i][j]=0.;
1.186     brouard  10697:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10698:     cens=ivector(1,n);
                   10699:     ageexmed=vector(1,n);
                   10700:     agecens=vector(1,n);
                   10701:     dcwave=ivector(1,n);
1.223     brouard  10702:                
1.126     brouard  10703:     for (i=1; i<=imx; i++){
                   10704:       dcwave[i]=-1;
                   10705:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10706:        if (s[m][i]>nlstate) {
                   10707:          dcwave[i]=m;
                   10708:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10709:          break;
                   10710:        }
1.126     brouard  10711:     }
1.226     brouard  10712:     
1.126     brouard  10713:     for (i=1; i<=imx; i++) {
                   10714:       if (wav[i]>0){
1.226     brouard  10715:        ageexmed[i]=agev[mw[1][i]][i];
                   10716:        j=wav[i];
                   10717:        agecens[i]=1.; 
                   10718:        
                   10719:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10720:          agecens[i]=agev[mw[j][i]][i];
                   10721:          cens[i]= 1;
                   10722:        }else if (ageexmed[i]< 1) 
                   10723:          cens[i]= -1;
                   10724:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10725:          cens[i]=0 ;
1.126     brouard  10726:       }
                   10727:       else cens[i]=-1;
                   10728:     }
                   10729:     
                   10730:     for (i=1;i<=NDIM;i++) {
                   10731:       for (j=1;j<=NDIM;j++)
1.226     brouard  10732:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10733:     }
                   10734:     
1.145     brouard  10735:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10736:     /*printf("%lf %lf", p[1], p[2]);*/
                   10737:     
                   10738:     
1.136     brouard  10739: #ifdef GSL
                   10740:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10741: #else
1.126     brouard  10742:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10743: #endif
1.201     brouard  10744:     strcpy(filerespow,"POW-MORT_"); 
                   10745:     strcat(filerespow,fileresu);
1.126     brouard  10746:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10747:       printf("Problem with resultfile: %s\n", filerespow);
                   10748:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10749:     }
1.136     brouard  10750: #ifdef GSL
                   10751:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10752: #else
1.126     brouard  10753:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10754: #endif
1.126     brouard  10755:     /*  for (i=1;i<=nlstate;i++)
                   10756:        for(j=1;j<=nlstate+ndeath;j++)
                   10757:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10758:     */
                   10759:     fprintf(ficrespow,"\n");
1.136     brouard  10760: #ifdef GSL
                   10761:     /* gsl starts here */ 
                   10762:     T = gsl_multimin_fminimizer_nmsimplex;
                   10763:     gsl_multimin_fminimizer *sfm = NULL;
                   10764:     gsl_vector *ss, *x;
                   10765:     gsl_multimin_function minex_func;
                   10766: 
                   10767:     /* Initial vertex size vector */
                   10768:     ss = gsl_vector_alloc (NDIM);
                   10769:     
                   10770:     if (ss == NULL){
                   10771:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10772:     }
                   10773:     /* Set all step sizes to 1 */
                   10774:     gsl_vector_set_all (ss, 0.001);
                   10775: 
                   10776:     /* Starting point */
1.126     brouard  10777:     
1.136     brouard  10778:     x = gsl_vector_alloc (NDIM);
                   10779:     
                   10780:     if (x == NULL){
                   10781:       gsl_vector_free(ss);
                   10782:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10783:     }
                   10784:   
                   10785:     /* Initialize method and iterate */
                   10786:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10787:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10788:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10789:     gsl_vector_set(x, 0, p[1]);
                   10790:     gsl_vector_set(x, 1, p[2]);
                   10791: 
                   10792:     minex_func.f = &gompertz_f;
                   10793:     minex_func.n = NDIM;
                   10794:     minex_func.params = (void *)&p; /* ??? */
                   10795:     
                   10796:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10797:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10798:     
                   10799:     printf("Iterations beginning .....\n\n");
                   10800:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10801: 
                   10802:     iteri=0;
                   10803:     while (rval == GSL_CONTINUE){
                   10804:       iteri++;
                   10805:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10806:       
                   10807:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10808:       fflush(0);
                   10809:       
                   10810:       if (status) 
                   10811:         break;
                   10812:       
                   10813:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10814:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10815:       
                   10816:       if (rval == GSL_SUCCESS)
                   10817:         printf ("converged to a local maximum at\n");
                   10818:       
                   10819:       printf("%5d ", iteri);
                   10820:       for (it = 0; it < NDIM; it++){
                   10821:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10822:       }
                   10823:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10824:     }
                   10825:     
                   10826:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10827:     
                   10828:     gsl_vector_free(x); /* initial values */
                   10829:     gsl_vector_free(ss); /* inital step size */
                   10830:     for (it=0; it<NDIM; it++){
                   10831:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10832:       fprintf(ficrespow," %.12lf", p[it]);
                   10833:     }
                   10834:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10835: #endif
                   10836: #ifdef POWELL
                   10837:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10838: #endif  
1.126     brouard  10839:     fclose(ficrespow);
                   10840:     
1.203     brouard  10841:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10842: 
                   10843:     for(i=1; i <=NDIM; i++)
                   10844:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10845:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10846:     
                   10847:     printf("\nCovariance matrix\n ");
1.203     brouard  10848:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10849:     for(i=1; i <=NDIM; i++) {
                   10850:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10851:                                printf("%f ",matcov[i][j]);
                   10852:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10853:       }
1.203     brouard  10854:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10855:     }
                   10856:     
                   10857:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10858:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10859:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10860:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10861:     }
1.126     brouard  10862:     lsurv=vector(1,AGESUP);
                   10863:     lpop=vector(1,AGESUP);
                   10864:     tpop=vector(1,AGESUP);
                   10865:     lsurv[agegomp]=100000;
                   10866:     
                   10867:     for (k=agegomp;k<=AGESUP;k++) {
                   10868:       agemortsup=k;
                   10869:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10870:     }
                   10871:     
                   10872:     for (k=agegomp;k<agemortsup;k++)
                   10873:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10874:     
                   10875:     for (k=agegomp;k<agemortsup;k++){
                   10876:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10877:       sumlpop=sumlpop+lpop[k];
                   10878:     }
                   10879:     
                   10880:     tpop[agegomp]=sumlpop;
                   10881:     for (k=agegomp;k<(agemortsup-3);k++){
                   10882:       /*  tpop[k+1]=2;*/
                   10883:       tpop[k+1]=tpop[k]-lpop[k];
                   10884:     }
                   10885:     
                   10886:     
                   10887:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10888:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10889:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10890:     
                   10891:     
                   10892:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10893:                ageminpar=50;
                   10894:                agemaxpar=100;
1.194     brouard  10895:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10896:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10897: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10898: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10899:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10900: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10901: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10902:     }else{
                   10903:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10904:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10905:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10906:                }
1.201     brouard  10907:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10908:                     stepm, weightopt,\
                   10909:                     model,imx,p,matcov,agemortsup);
                   10910:     
                   10911:     free_vector(lsurv,1,AGESUP);
                   10912:     free_vector(lpop,1,AGESUP);
                   10913:     free_vector(tpop,1,AGESUP);
1.220     brouard  10914:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10915:     free_ivector(cens,1,n);
                   10916:     free_vector(agecens,1,n);
                   10917:     free_ivector(dcwave,1,n);
1.220     brouard  10918: #ifdef GSL
1.136     brouard  10919: #endif
1.186     brouard  10920:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10921:   /* Standard  */
                   10922:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10923:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10924:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10925:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10926:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10927:     for (k=1; k<=npar;k++)
                   10928:       printf(" %d %8.5f",k,p[k]);
                   10929:     printf("\n");
1.205     brouard  10930:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10931:       /* mlikeli uses func not funcone */
1.247     brouard  10932:       /* for(i=1;i<nlstate;i++){ */
                   10933:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10934:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10935:       /* } */
1.205     brouard  10936:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10937:     }
                   10938:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10939:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10940:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10941:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10942:     }
                   10943:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10944:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10945:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10946:     for (k=1; k<=npar;k++)
                   10947:       printf(" %d %8.5f",k,p[k]);
                   10948:     printf("\n");
                   10949:     
                   10950:     /*--------- results files --------------*/
1.224     brouard  10951:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10952:     
                   10953:     
                   10954:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10955:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10956:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10957:     for(i=1,jk=1; i <=nlstate; i++){
                   10958:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10959:        if (k != i) {
                   10960:          printf("%d%d ",i,k);
                   10961:          fprintf(ficlog,"%d%d ",i,k);
                   10962:          fprintf(ficres,"%1d%1d ",i,k);
                   10963:          for(j=1; j <=ncovmodel; j++){
                   10964:            printf("%12.7f ",p[jk]);
                   10965:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10966:            fprintf(ficres,"%12.7f ",p[jk]);
                   10967:            jk++; 
                   10968:          }
                   10969:          printf("\n");
                   10970:          fprintf(ficlog,"\n");
                   10971:          fprintf(ficres,"\n");
                   10972:        }
1.126     brouard  10973:       }
                   10974:     }
1.203     brouard  10975:     if(mle != 0){
                   10976:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10977:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10978:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10979:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10980:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10981:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10982:        for(k=1; k <=(nlstate+ndeath); k++){
                   10983:          if (k != i) {
                   10984:            printf("%d%d ",i,k);
                   10985:            fprintf(ficlog,"%d%d ",i,k);
                   10986:            for(j=1; j <=ncovmodel; j++){
                   10987:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10988:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10989:              jk++; 
                   10990:            }
                   10991:            printf("\n");
                   10992:            fprintf(ficlog,"\n");
                   10993:          }
                   10994:        }
1.193     brouard  10995:       }
1.203     brouard  10996:     } /* end of hesscov and Wald tests */
1.225     brouard  10997:     
1.203     brouard  10998:     /*  */
1.126     brouard  10999:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11000:     printf("# Scales (for hessian or gradient estimation)\n");
                   11001:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11002:     for(i=1,jk=1; i <=nlstate; i++){
                   11003:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11004:        if (j!=i) {
                   11005:          fprintf(ficres,"%1d%1d",i,j);
                   11006:          printf("%1d%1d",i,j);
                   11007:          fprintf(ficlog,"%1d%1d",i,j);
                   11008:          for(k=1; k<=ncovmodel;k++){
                   11009:            printf(" %.5e",delti[jk]);
                   11010:            fprintf(ficlog," %.5e",delti[jk]);
                   11011:            fprintf(ficres," %.5e",delti[jk]);
                   11012:            jk++;
                   11013:          }
                   11014:          printf("\n");
                   11015:          fprintf(ficlog,"\n");
                   11016:          fprintf(ficres,"\n");
                   11017:        }
1.126     brouard  11018:       }
                   11019:     }
                   11020:     
                   11021:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11022:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11023:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11024:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11025:     /* # 121 Var(a12)\n\ */
                   11026:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11027:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11028:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11029:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11030:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11031:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11032:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11033:     
                   11034:     
                   11035:     /* Just to have a covariance matrix which will be more understandable
                   11036:        even is we still don't want to manage dictionary of variables
                   11037:     */
                   11038:     for(itimes=1;itimes<=2;itimes++){
                   11039:       jj=0;
                   11040:       for(i=1; i <=nlstate; i++){
1.225     brouard  11041:        for(j=1; j <=nlstate+ndeath; j++){
                   11042:          if(j==i) continue;
                   11043:          for(k=1; k<=ncovmodel;k++){
                   11044:            jj++;
                   11045:            ca[0]= k+'a'-1;ca[1]='\0';
                   11046:            if(itimes==1){
                   11047:              if(mle>=1)
                   11048:                printf("#%1d%1d%d",i,j,k);
                   11049:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11050:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11051:            }else{
                   11052:              if(mle>=1)
                   11053:                printf("%1d%1d%d",i,j,k);
                   11054:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11055:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11056:            }
                   11057:            ll=0;
                   11058:            for(li=1;li <=nlstate; li++){
                   11059:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11060:                if(lj==li) continue;
                   11061:                for(lk=1;lk<=ncovmodel;lk++){
                   11062:                  ll++;
                   11063:                  if(ll<=jj){
                   11064:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11065:                    if(ll<jj){
                   11066:                      if(itimes==1){
                   11067:                        if(mle>=1)
                   11068:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11069:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11070:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11071:                      }else{
                   11072:                        if(mle>=1)
                   11073:                          printf(" %.5e",matcov[jj][ll]); 
                   11074:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11075:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11076:                      }
                   11077:                    }else{
                   11078:                      if(itimes==1){
                   11079:                        if(mle>=1)
                   11080:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11081:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11082:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11083:                      }else{
                   11084:                        if(mle>=1)
                   11085:                          printf(" %.7e",matcov[jj][ll]); 
                   11086:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11087:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11088:                      }
                   11089:                    }
                   11090:                  }
                   11091:                } /* end lk */
                   11092:              } /* end lj */
                   11093:            } /* end li */
                   11094:            if(mle>=1)
                   11095:              printf("\n");
                   11096:            fprintf(ficlog,"\n");
                   11097:            fprintf(ficres,"\n");
                   11098:            numlinepar++;
                   11099:          } /* end k*/
                   11100:        } /*end j */
1.126     brouard  11101:       } /* end i */
                   11102:     } /* end itimes */
                   11103:     
                   11104:     fflush(ficlog);
                   11105:     fflush(ficres);
1.225     brouard  11106:     while(fgets(line, MAXLINE, ficpar)) {
                   11107:       /* If line starts with a # it is a comment */
                   11108:       if (line[0] == '#') {
                   11109:        numlinepar++;
                   11110:        fputs(line,stdout);
                   11111:        fputs(line,ficparo);
                   11112:        fputs(line,ficlog);
                   11113:        continue;
                   11114:       }else
                   11115:        break;
                   11116:     }
                   11117:     
1.209     brouard  11118:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11119:     /*   ungetc(c,ficpar); */
                   11120:     /*   fgets(line, MAXLINE, ficpar); */
                   11121:     /*   fputs(line,stdout); */
                   11122:     /*   fputs(line,ficparo); */
                   11123:     /* } */
                   11124:     /* ungetc(c,ficpar); */
1.126     brouard  11125:     
                   11126:     estepm=0;
1.209     brouard  11127:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11128:       
                   11129:       if (num_filled != 6) {
                   11130:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11131:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11132:        goto end;
                   11133:       }
                   11134:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11135:     }
                   11136:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11137:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11138:     
1.209     brouard  11139:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11140:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11141:     if (fage <= 2) {
                   11142:       bage = ageminpar;
                   11143:       fage = agemaxpar;
                   11144:     }
                   11145:     
                   11146:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11147:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11148:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11149:                
1.186     brouard  11150:     /* Other stuffs, more or less useful */    
1.254     brouard  11151:     while(fgets(line, MAXLINE, ficpar)) {
                   11152:       /* If line starts with a # it is a comment */
                   11153:       if (line[0] == '#') {
                   11154:        numlinepar++;
                   11155:        fputs(line,stdout);
                   11156:        fputs(line,ficparo);
                   11157:        fputs(line,ficlog);
                   11158:        continue;
                   11159:       }else
                   11160:        break;
                   11161:     }
                   11162: 
                   11163:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11164:       
                   11165:       if (num_filled != 7) {
                   11166:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11167:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11168:        goto end;
                   11169:       }
                   11170:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11171:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11172:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11173:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11174:     }
1.254     brouard  11175: 
                   11176:     while(fgets(line, MAXLINE, ficpar)) {
                   11177:       /* If line starts with a # it is a comment */
                   11178:       if (line[0] == '#') {
                   11179:        numlinepar++;
                   11180:        fputs(line,stdout);
                   11181:        fputs(line,ficparo);
                   11182:        fputs(line,ficlog);
                   11183:        continue;
                   11184:       }else
                   11185:        break;
1.126     brouard  11186:     }
                   11187:     
                   11188:     
                   11189:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11190:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11191:     
1.254     brouard  11192:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11193:       if (num_filled != 1) {
                   11194:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11195:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11196:        goto end;
                   11197:       }
                   11198:       printf("pop_based=%d\n",popbased);
                   11199:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11200:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11201:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11202:     }
                   11203:      
1.258     brouard  11204:     /* Results */
                   11205:     nresult=0;
                   11206:     do{
                   11207:       if(!fgets(line, MAXLINE, ficpar)){
                   11208:        endishere=1;
                   11209:        parameterline=14;
                   11210:       }else if (line[0] == '#') {
                   11211:        /* If line starts with a # it is a comment */
1.254     brouard  11212:        numlinepar++;
                   11213:        fputs(line,stdout);
                   11214:        fputs(line,ficparo);
                   11215:        fputs(line,ficlog);
                   11216:        continue;
1.258     brouard  11217:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   11218:        parameterline=11;
                   11219:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   11220:        parameterline=12;
                   11221:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   11222:        parameterline=13;
                   11223:       else{
                   11224:        parameterline=14;
1.254     brouard  11225:       }
1.258     brouard  11226:       switch (parameterline){ 
                   11227:       case 11:
                   11228:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11229:          if (num_filled != 8) {
                   11230:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11231:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11232:            goto end;
                   11233:          }
                   11234:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11235:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11236:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11237:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11238:          /* day and month of proj2 are not used but only year anproj2.*/
                   11239:        }
1.254     brouard  11240:        break;
1.258     brouard  11241:       case 12:
                   11242:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   11243:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   11244:          if (num_filled != 8) {
                   11245:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11246:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 finloal-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11247:            goto end;
                   11248:          }
                   11249:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11250:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11251:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11252:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11253:          /* day and month of proj2 are not used but only year anproj2.*/
                   11254:        }
1.230     brouard  11255:        break;
1.258     brouard  11256:       case 13:
                   11257:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   11258:          if (num_filled == 0){
                   11259:            resultline[0]='\0';
                   11260:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11261:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11262:            break;
                   11263:          } else if (num_filled != 1){
                   11264:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11265:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11266:          }
                   11267:          nresult++; /* Sum of resultlines */
                   11268:          printf("Result %d: result=%s\n",nresult, resultline);
                   11269:          if(nresult > MAXRESULTLINES){
                   11270:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11271:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11272:            goto end;
                   11273:          }
                   11274:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   11275:          fprintf(ficparo,"result: %s\n",resultline);
                   11276:          fprintf(ficres,"result: %s\n",resultline);
                   11277:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11278:          break;
1.258     brouard  11279:        case 14: 
1.259     brouard  11280:          if(ncovmodel >2 && nresult==0 ){
                   11281:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  11282:            goto end;
                   11283:          }
1.259     brouard  11284:          break;
1.258     brouard  11285:        default:
                   11286:          nresult=1;
                   11287:          decoderesult(".",nresult ); /* No covariate */
                   11288:        }
                   11289:       } /* End switch parameterline */
                   11290:     }while(endishere==0); /* End do */
1.126     brouard  11291:     
1.230     brouard  11292:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11293:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11294:     
                   11295:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11296:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11297:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11298: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11299: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11300:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11301: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11302: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11303:     }else{
1.218     brouard  11304:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11305:     }
                   11306:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  11307:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  11308:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11309:                
1.225     brouard  11310:     /*------------ free_vector  -------------*/
                   11311:     /*  chdir(path); */
1.220     brouard  11312:                
1.215     brouard  11313:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11314:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11315:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11316:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11317:     free_lvector(num,1,n);
                   11318:     free_vector(agedc,1,n);
                   11319:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11320:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11321:     fclose(ficparo);
                   11322:     fclose(ficres);
1.220     brouard  11323:                
                   11324:                
1.186     brouard  11325:     /* Other results (useful)*/
1.220     brouard  11326:                
                   11327:                
1.126     brouard  11328:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11329:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11330:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11331:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11332:     fclose(ficrespl);
                   11333: 
                   11334:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11335:     /*#include "hpijx.h"*/
                   11336:     hPijx(p, bage, fage);
1.145     brouard  11337:     fclose(ficrespij);
1.227     brouard  11338:     
1.220     brouard  11339:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11340:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11341:     k=1;
1.126     brouard  11342:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11343:     
1.219     brouard  11344:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11345:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11346:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11347:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11348:        for(k=1;k<=ncovcombmax;k++)
                   11349:          probs[i][j][k]=0.;
1.219     brouard  11350:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11351:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11352:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11353:       for(i=1;i<=AGESUP;i++)
                   11354:        for(j=1;j<=nlstate;j++)
                   11355:          for(k=1;k<=ncovcombmax;k++)
                   11356:            mobaverages[i][j][k]=0.;
1.219     brouard  11357:       mobaverage=mobaverages;
                   11358:       if (mobilav!=0) {
1.235     brouard  11359:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  11360:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  11361:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11362:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11363:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11364:        }
1.219     brouard  11365:       }
                   11366:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11367:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11368:       else if (mobilavproj !=0) {
1.235     brouard  11369:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  11370:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  11371:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11372:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11373:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11374:        }
1.219     brouard  11375:       }
                   11376:     }/* end if moving average */
1.227     brouard  11377:     
1.126     brouard  11378:     /*---------- Forecasting ------------------*/
                   11379:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11380:     if(prevfcast==1){
                   11381:       /*    if(stepm ==1){*/
1.225     brouard  11382:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11383:     }
1.217     brouard  11384:     if(backcast==1){
1.219     brouard  11385:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11386:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11387:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11388: 
                   11389:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11390: 
                   11391:       bprlim=matrix(1,nlstate,1,nlstate);
                   11392:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11393:       fclose(ficresplb);
                   11394: 
1.222     brouard  11395:       hBijx(p, bage, fage, mobaverage);
                   11396:       fclose(ficrespijb);
1.219     brouard  11397:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11398: 
                   11399:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11400:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11401:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11402:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11403:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11404:     }
1.217     brouard  11405:     
1.186     brouard  11406:  
                   11407:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11408: 
1.215     brouard  11409:     free_ivector(wav,1,imx);
                   11410:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11411:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11412:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11413:                
                   11414:                
1.127     brouard  11415:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11416:                
1.201     brouard  11417:     strcpy(filerese,"E_");
                   11418:     strcat(filerese,fileresu);
1.126     brouard  11419:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11420:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11421:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11422:     }
1.208     brouard  11423:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11424:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11425: 
                   11426:     pstamp(ficreseij);
1.219     brouard  11427:                
1.235     brouard  11428:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11429:     if (cptcovn < 1){i1=1;}
                   11430:     
                   11431:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11432:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11433:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11434:        continue;
1.219     brouard  11435:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11436:       printf("\n#****** ");
1.225     brouard  11437:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11438:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11439:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11440:       }
                   11441:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11442:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11443:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11444:       }
                   11445:       fprintf(ficreseij,"******\n");
1.235     brouard  11446:       printf("******\n");
1.219     brouard  11447:       
                   11448:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11449:       oldm=oldms;savm=savms;
1.235     brouard  11450:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11451:       
1.219     brouard  11452:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11453:     }
                   11454:     fclose(ficreseij);
1.208     brouard  11455:     printf("done evsij\n");fflush(stdout);
                   11456:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11457:                
1.227     brouard  11458:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11459:                
                   11460:                
1.201     brouard  11461:     strcpy(filerest,"T_");
                   11462:     strcat(filerest,fileresu);
1.127     brouard  11463:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11464:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11465:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11466:     }
1.208     brouard  11467:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11468:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11469:                
1.126     brouard  11470: 
1.201     brouard  11471:     strcpy(fileresstde,"STDE_");
                   11472:     strcat(fileresstde,fileresu);
1.126     brouard  11473:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11474:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11475:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11476:     }
1.227     brouard  11477:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11478:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11479: 
1.201     brouard  11480:     strcpy(filerescve,"CVE_");
                   11481:     strcat(filerescve,fileresu);
1.126     brouard  11482:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11483:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11484:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11485:     }
1.227     brouard  11486:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11487:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11488: 
1.201     brouard  11489:     strcpy(fileresv,"V_");
                   11490:     strcat(fileresv,fileresu);
1.126     brouard  11491:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11492:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11493:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11494:     }
1.227     brouard  11495:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11496:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11497: 
1.145     brouard  11498:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11499:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11500:           
1.235     brouard  11501:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11502:     if (cptcovn < 1){i1=1;}
                   11503:     
                   11504:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11505:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11506:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11507:        continue;
1.242     brouard  11508:       printf("\n#****** Result for:");
                   11509:       fprintf(ficrest,"\n#****** Result for:");
                   11510:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11511:       for(j=1;j<=cptcoveff;j++){ 
                   11512:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11513:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11514:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11515:       }
1.235     brouard  11516:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11517:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11518:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11519:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11520:       }        
1.208     brouard  11521:       fprintf(ficrest,"******\n");
1.227     brouard  11522:       fprintf(ficlog,"******\n");
                   11523:       printf("******\n");
1.208     brouard  11524:       
                   11525:       fprintf(ficresstdeij,"\n#****** ");
                   11526:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11527:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11528:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11529:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11530:       }
1.235     brouard  11531:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11532:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11533:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11534:       }        
1.208     brouard  11535:       fprintf(ficresstdeij,"******\n");
                   11536:       fprintf(ficrescveij,"******\n");
                   11537:       
                   11538:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11539:       /* pstamp(ficresvij); */
1.225     brouard  11540:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11541:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11542:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11543:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11544:       }        
1.208     brouard  11545:       fprintf(ficresvij,"******\n");
                   11546:       
                   11547:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11548:       oldm=oldms;savm=savms;
1.235     brouard  11549:       printf(" cvevsij ");
                   11550:       fprintf(ficlog, " cvevsij ");
                   11551:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11552:       printf(" end cvevsij \n ");
                   11553:       fprintf(ficlog, " end cvevsij \n ");
                   11554:       
                   11555:       /*
                   11556:        */
                   11557:       /* goto endfree; */
                   11558:       
                   11559:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11560:       pstamp(ficrest);
                   11561:       
                   11562:       
                   11563:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11564:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11565:        cptcod= 0; /* To be deleted */
                   11566:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11567:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11568:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11569:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11570:        if(vpopbased==1)
                   11571:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11572:        else
                   11573:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11574:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11575:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11576:        fprintf(ficrest,"\n");
                   11577:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11578:        epj=vector(1,nlstate+1);
                   11579:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11580:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11581:        for(age=bage; age <=fage ;age++){
1.235     brouard  11582:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11583:          if (vpopbased==1) {
                   11584:            if(mobilav ==0){
                   11585:              for(i=1; i<=nlstate;i++)
                   11586:                prlim[i][i]=probs[(int)age][i][k];
                   11587:            }else{ /* mobilav */ 
                   11588:              for(i=1; i<=nlstate;i++)
                   11589:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11590:            }
                   11591:          }
1.219     brouard  11592:          
1.227     brouard  11593:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11594:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11595:          /* printf(" age %4.0f ",age); */
                   11596:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11597:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11598:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11599:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11600:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11601:            }
                   11602:            epj[nlstate+1] +=epj[j];
                   11603:          }
                   11604:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11605:          
1.227     brouard  11606:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11607:            for(j=1;j <=nlstate;j++)
                   11608:              vepp += vareij[i][j][(int)age];
                   11609:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11610:          for(j=1;j <=nlstate;j++){
                   11611:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11612:          }
                   11613:          fprintf(ficrest,"\n");
                   11614:        }
1.208     brouard  11615:       } /* End vpopbased */
                   11616:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11617:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11618:       free_vector(epj,1,nlstate+1);
1.235     brouard  11619:       printf("done selection\n");fflush(stdout);
                   11620:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11621:       
1.145     brouard  11622:       /*}*/
1.235     brouard  11623:     } /* End k selection */
1.227     brouard  11624: 
                   11625:     printf("done State-specific expectancies\n");fflush(stdout);
                   11626:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11627: 
1.126     brouard  11628:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11629:     
1.201     brouard  11630:     strcpy(fileresvpl,"VPL_");
                   11631:     strcat(fileresvpl,fileresu);
1.126     brouard  11632:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11633:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11634:       exit(0);
                   11635:     }
1.208     brouard  11636:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11637:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11638:     
1.145     brouard  11639:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11640:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11641:     
1.235     brouard  11642:     i1=pow(2,cptcoveff);
                   11643:     if (cptcovn < 1){i1=1;}
                   11644: 
                   11645:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11646:     for(k=1; k<=i1;k++){
1.253     brouard  11647:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11648:        continue;
1.227     brouard  11649:       fprintf(ficresvpl,"\n#****** ");
                   11650:       printf("\n#****** ");
                   11651:       fprintf(ficlog,"\n#****** ");
                   11652:       for(j=1;j<=cptcoveff;j++) {
                   11653:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11654:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11655:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11656:       }
1.235     brouard  11657:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11658:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11659:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11660:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11661:       }        
1.227     brouard  11662:       fprintf(ficresvpl,"******\n");
                   11663:       printf("******\n");
                   11664:       fprintf(ficlog,"******\n");
                   11665:       
                   11666:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11667:       oldm=oldms;savm=savms;
1.235     brouard  11668:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11669:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11670:       /*}*/
1.126     brouard  11671:     }
1.227     brouard  11672:     
1.126     brouard  11673:     fclose(ficresvpl);
1.208     brouard  11674:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11675:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11676:     
                   11677:     free_vector(weight,1,n);
                   11678:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11679:     free_imatrix(s,1,maxwav+1,1,n);
                   11680:     free_matrix(anint,1,maxwav,1,n); 
                   11681:     free_matrix(mint,1,maxwav,1,n);
                   11682:     free_ivector(cod,1,n);
                   11683:     free_ivector(tab,1,NCOVMAX);
                   11684:     fclose(ficresstdeij);
                   11685:     fclose(ficrescveij);
                   11686:     fclose(ficresvij);
                   11687:     fclose(ficrest);
                   11688:     fclose(ficpar);
                   11689:     
                   11690:     
1.126     brouard  11691:     /*---------- End : free ----------------*/
1.219     brouard  11692:     if (mobilav!=0 ||mobilavproj !=0)
                   11693:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11694:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11695:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11696:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11697:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11698:   /* endfree:*/
                   11699:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11700:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11701:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11702:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11703:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11704:   free_matrix(coqvar,1,maxwav,1,n);
                   11705:   free_matrix(covar,0,NCOVMAX,1,n);
                   11706:   free_matrix(matcov,1,npar,1,npar);
                   11707:   free_matrix(hess,1,npar,1,npar);
                   11708:   /*free_vector(delti,1,npar);*/
                   11709:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11710:   free_matrix(agev,1,maxwav,1,imx);
                   11711:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11712:   
                   11713:   free_ivector(ncodemax,1,NCOVMAX);
                   11714:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11715:   free_ivector(Dummy,-1,NCOVMAX);
                   11716:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11717:   free_ivector(DummyV,1,NCOVMAX);
                   11718:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11719:   free_ivector(Typevar,-1,NCOVMAX);
                   11720:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11721:   free_ivector(TvarsQ,1,NCOVMAX);
                   11722:   free_ivector(TvarsQind,1,NCOVMAX);
                   11723:   free_ivector(TvarsD,1,NCOVMAX);
                   11724:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11725:   free_ivector(TvarFD,1,NCOVMAX);
                   11726:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11727:   free_ivector(TvarF,1,NCOVMAX);
                   11728:   free_ivector(TvarFind,1,NCOVMAX);
                   11729:   free_ivector(TvarV,1,NCOVMAX);
                   11730:   free_ivector(TvarVind,1,NCOVMAX);
                   11731:   free_ivector(TvarA,1,NCOVMAX);
                   11732:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11733:   free_ivector(TvarFQ,1,NCOVMAX);
                   11734:   free_ivector(TvarFQind,1,NCOVMAX);
                   11735:   free_ivector(TvarVD,1,NCOVMAX);
                   11736:   free_ivector(TvarVDind,1,NCOVMAX);
                   11737:   free_ivector(TvarVQ,1,NCOVMAX);
                   11738:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11739:   free_ivector(Tvarsel,1,NCOVMAX);
                   11740:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11741:   free_ivector(Tposprod,1,NCOVMAX);
                   11742:   free_ivector(Tprod,1,NCOVMAX);
                   11743:   free_ivector(Tvaraff,1,NCOVMAX);
                   11744:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11745:   free_ivector(Tage,1,NCOVMAX);
                   11746:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11747:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11748:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11749:   
                   11750:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11751:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11752:   fflush(fichtm);
                   11753:   fflush(ficgp);
                   11754:   
1.227     brouard  11755:   
1.126     brouard  11756:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11757:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11758:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11759:   }else{
                   11760:     printf("End of Imach\n");
                   11761:     fprintf(ficlog,"End of Imach\n");
                   11762:   }
                   11763:   printf("See log file on %s\n",filelog);
                   11764:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11765:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11766:   rend_time = time(NULL);  
                   11767:   end_time = *localtime(&rend_time);
                   11768:   /* tml = *localtime(&end_time.tm_sec); */
                   11769:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11770:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11771:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11772:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11773:   
1.157     brouard  11774:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11775:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11776:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11777:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11778: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11779:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11780:   fclose(fichtm);
                   11781:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11782:   fclose(fichtmcov);
                   11783:   fclose(ficgp);
                   11784:   fclose(ficlog);
                   11785:   /*------ End -----------*/
1.227     brouard  11786:   
                   11787:   
                   11788:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11789: #ifdef WIN32
1.227     brouard  11790:   if (_chdir(pathcd) != 0)
                   11791:     printf("Can't move to directory %s!\n",path);
                   11792:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11793: #else
1.227     brouard  11794:     if(chdir(pathcd) != 0)
                   11795:       printf("Can't move to directory %s!\n", path);
                   11796:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11797: #endif 
1.126     brouard  11798:     printf("Current directory %s!\n",pathcd);
                   11799:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11800:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11801: #ifdef _WIN32
1.126     brouard  11802:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11803: #endif
                   11804:   if(!stat(plotcmd,&info)){
1.158     brouard  11805:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11806:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11807:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11808:     }else
                   11809:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11810: #ifdef __unix
1.126     brouard  11811:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11812:     if(!stat(plotcmd,&info)){
1.158     brouard  11813:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11814:     }else
                   11815:       strcpy(pplotcmd,plotcmd);
                   11816: #endif
                   11817:   }else
                   11818:     strcpy(pplotcmd,plotcmd);
                   11819:   
                   11820:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11821:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11822:   
1.126     brouard  11823:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11824:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11825:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11826:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11827:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11828:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11829:   }
1.158     brouard  11830:   printf(" Successful, please wait...");
1.126     brouard  11831:   while (z[0] != 'q') {
                   11832:     /* chdir(path); */
1.154     brouard  11833:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11834:     scanf("%s",z);
                   11835: /*     if (z[0] == 'c') system("./imach"); */
                   11836:     if (z[0] == 'e') {
1.158     brouard  11837: #ifdef __APPLE__
1.152     brouard  11838:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11839: #elif __linux
                   11840:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11841: #else
1.152     brouard  11842:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11843: #endif
                   11844:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11845:       system(pplotcmd);
1.126     brouard  11846:     }
                   11847:     else if (z[0] == 'g') system(plotcmd);
                   11848:     else if (z[0] == 'q') exit(0);
                   11849:   }
1.227     brouard  11850: end:
1.126     brouard  11851:   while (z[0] != 'q') {
1.195     brouard  11852:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11853:     scanf("%s",z);
                   11854:   }
                   11855: }

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