Annotation of imach/src/imach.c, revision 1.263

1.263   ! brouard     1: /* $Id: imach.c,v 1.262 2017/04/18 16:48:12 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.263   ! brouard     4:   Revision 1.262  2017/04/18 16:48:12  brouard
        !             5:   *** empty log message ***
        !             6: 
1.262     brouard     7:   Revision 1.261  2017/04/05 10:14:09  brouard
                      8:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                      9: 
1.261     brouard    10:   Revision 1.260  2017/04/04 17:46:59  brouard
                     11:   Summary: Gnuplot indexations fixed (humm)
                     12: 
1.260     brouard    13:   Revision 1.259  2017/04/04 13:01:16  brouard
                     14:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     15: 
1.259     brouard    16:   Revision 1.258  2017/04/03 10:17:47  brouard
                     17:   Summary: Version 0.99r12
                     18: 
                     19:   Some cleanings, conformed with updated documentation.
                     20: 
1.258     brouard    21:   Revision 1.257  2017/03/29 16:53:30  brouard
                     22:   Summary: Temp
                     23: 
1.257     brouard    24:   Revision 1.256  2017/03/27 05:50:23  brouard
                     25:   Summary: Temporary
                     26: 
1.256     brouard    27:   Revision 1.255  2017/03/08 16:02:28  brouard
                     28:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     29: 
1.255     brouard    30:   Revision 1.254  2017/03/08 07:13:00  brouard
                     31:   Summary: Fixing data parameter line
                     32: 
1.254     brouard    33:   Revision 1.253  2016/12/15 11:59:41  brouard
                     34:   Summary: 0.99 in progress
                     35: 
1.253     brouard    36:   Revision 1.252  2016/09/15 21:15:37  brouard
                     37:   *** empty log message ***
                     38: 
1.252     brouard    39:   Revision 1.251  2016/09/15 15:01:13  brouard
                     40:   Summary: not working
                     41: 
1.251     brouard    42:   Revision 1.250  2016/09/08 16:07:27  brouard
                     43:   Summary: continue
                     44: 
1.250     brouard    45:   Revision 1.249  2016/09/07 17:14:18  brouard
                     46:   Summary: Starting values from frequencies
                     47: 
1.249     brouard    48:   Revision 1.248  2016/09/07 14:10:18  brouard
                     49:   *** empty log message ***
                     50: 
1.248     brouard    51:   Revision 1.247  2016/09/02 11:11:21  brouard
                     52:   *** empty log message ***
                     53: 
1.247     brouard    54:   Revision 1.246  2016/09/02 08:49:22  brouard
                     55:   *** empty log message ***
                     56: 
1.246     brouard    57:   Revision 1.245  2016/09/02 07:25:01  brouard
                     58:   *** empty log message ***
                     59: 
1.245     brouard    60:   Revision 1.244  2016/09/02 07:17:34  brouard
                     61:   *** empty log message ***
                     62: 
1.244     brouard    63:   Revision 1.243  2016/09/02 06:45:35  brouard
                     64:   *** empty log message ***
                     65: 
1.243     brouard    66:   Revision 1.242  2016/08/30 15:01:20  brouard
                     67:   Summary: Fixing a lots
                     68: 
1.242     brouard    69:   Revision 1.241  2016/08/29 17:17:25  brouard
                     70:   Summary: gnuplot problem in Back projection to fix
                     71: 
1.241     brouard    72:   Revision 1.240  2016/08/29 07:53:18  brouard
                     73:   Summary: Better
                     74: 
1.240     brouard    75:   Revision 1.239  2016/08/26 15:51:03  brouard
                     76:   Summary: Improvement in Powell output in order to copy and paste
                     77: 
                     78:   Author:
                     79: 
1.239     brouard    80:   Revision 1.238  2016/08/26 14:23:35  brouard
                     81:   Summary: Starting tests of 0.99
                     82: 
1.238     brouard    83:   Revision 1.237  2016/08/26 09:20:19  brouard
                     84:   Summary: to valgrind
                     85: 
1.237     brouard    86:   Revision 1.236  2016/08/25 10:50:18  brouard
                     87:   *** empty log message ***
                     88: 
1.236     brouard    89:   Revision 1.235  2016/08/25 06:59:23  brouard
                     90:   *** empty log message ***
                     91: 
1.235     brouard    92:   Revision 1.234  2016/08/23 16:51:20  brouard
                     93:   *** empty log message ***
                     94: 
1.234     brouard    95:   Revision 1.233  2016/08/23 07:40:50  brouard
                     96:   Summary: not working
                     97: 
1.233     brouard    98:   Revision 1.232  2016/08/22 14:20:21  brouard
                     99:   Summary: not working
                    100: 
1.232     brouard   101:   Revision 1.231  2016/08/22 07:17:15  brouard
                    102:   Summary: not working
                    103: 
1.231     brouard   104:   Revision 1.230  2016/08/22 06:55:53  brouard
                    105:   Summary: Not working
                    106: 
1.230     brouard   107:   Revision 1.229  2016/07/23 09:45:53  brouard
                    108:   Summary: Completing for func too
                    109: 
1.229     brouard   110:   Revision 1.228  2016/07/22 17:45:30  brouard
                    111:   Summary: Fixing some arrays, still debugging
                    112: 
1.227     brouard   113:   Revision 1.226  2016/07/12 18:42:34  brouard
                    114:   Summary: temp
                    115: 
1.226     brouard   116:   Revision 1.225  2016/07/12 08:40:03  brouard
                    117:   Summary: saving but not running
                    118: 
1.225     brouard   119:   Revision 1.224  2016/07/01 13:16:01  brouard
                    120:   Summary: Fixes
                    121: 
1.224     brouard   122:   Revision 1.223  2016/02/19 09:23:35  brouard
                    123:   Summary: temporary
                    124: 
1.223     brouard   125:   Revision 1.222  2016/02/17 08:14:50  brouard
                    126:   Summary: Probably last 0.98 stable version 0.98r6
                    127: 
1.222     brouard   128:   Revision 1.221  2016/02/15 23:35:36  brouard
                    129:   Summary: minor bug
                    130: 
1.220     brouard   131:   Revision 1.219  2016/02/15 00:48:12  brouard
                    132:   *** empty log message ***
                    133: 
1.219     brouard   134:   Revision 1.218  2016/02/12 11:29:23  brouard
                    135:   Summary: 0.99 Back projections
                    136: 
1.218     brouard   137:   Revision 1.217  2015/12/23 17:18:31  brouard
                    138:   Summary: Experimental backcast
                    139: 
1.217     brouard   140:   Revision 1.216  2015/12/18 17:32:11  brouard
                    141:   Summary: 0.98r4 Warning and status=-2
                    142: 
                    143:   Version 0.98r4 is now:
                    144:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    145:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    146:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    147: 
1.216     brouard   148:   Revision 1.215  2015/12/16 08:52:24  brouard
                    149:   Summary: 0.98r4 working
                    150: 
1.215     brouard   151:   Revision 1.214  2015/12/16 06:57:54  brouard
                    152:   Summary: temporary not working
                    153: 
1.214     brouard   154:   Revision 1.213  2015/12/11 18:22:17  brouard
                    155:   Summary: 0.98r4
                    156: 
1.213     brouard   157:   Revision 1.212  2015/11/21 12:47:24  brouard
                    158:   Summary: minor typo
                    159: 
1.212     brouard   160:   Revision 1.211  2015/11/21 12:41:11  brouard
                    161:   Summary: 0.98r3 with some graph of projected cross-sectional
                    162: 
                    163:   Author: Nicolas Brouard
                    164: 
1.211     brouard   165:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   166:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   167:   Summary: Adding ftolpl parameter
                    168:   Author: N Brouard
                    169: 
                    170:   We had difficulties to get smoothed confidence intervals. It was due
                    171:   to the period prevalence which wasn't computed accurately. The inner
                    172:   parameter ftolpl is now an outer parameter of the .imach parameter
                    173:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    174:   computation are long.
                    175: 
1.209     brouard   176:   Revision 1.208  2015/11/17 14:31:57  brouard
                    177:   Summary: temporary
                    178: 
1.208     brouard   179:   Revision 1.207  2015/10/27 17:36:57  brouard
                    180:   *** empty log message ***
                    181: 
1.207     brouard   182:   Revision 1.206  2015/10/24 07:14:11  brouard
                    183:   *** empty log message ***
                    184: 
1.206     brouard   185:   Revision 1.205  2015/10/23 15:50:53  brouard
                    186:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    187: 
1.205     brouard   188:   Revision 1.204  2015/10/01 16:20:26  brouard
                    189:   Summary: Some new graphs of contribution to likelihood
                    190: 
1.204     brouard   191:   Revision 1.203  2015/09/30 17:45:14  brouard
                    192:   Summary: looking at better estimation of the hessian
                    193: 
                    194:   Also a better criteria for convergence to the period prevalence And
                    195:   therefore adding the number of years needed to converge. (The
                    196:   prevalence in any alive state shold sum to one
                    197: 
1.203     brouard   198:   Revision 1.202  2015/09/22 19:45:16  brouard
                    199:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    200: 
1.202     brouard   201:   Revision 1.201  2015/09/15 17:34:58  brouard
                    202:   Summary: 0.98r0
                    203: 
                    204:   - Some new graphs like suvival functions
                    205:   - Some bugs fixed like model=1+age+V2.
                    206: 
1.201     brouard   207:   Revision 1.200  2015/09/09 16:53:55  brouard
                    208:   Summary: Big bug thanks to Flavia
                    209: 
                    210:   Even model=1+age+V2. did not work anymore
                    211: 
1.200     brouard   212:   Revision 1.199  2015/09/07 14:09:23  brouard
                    213:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    214: 
1.199     brouard   215:   Revision 1.198  2015/09/03 07:14:39  brouard
                    216:   Summary: 0.98q5 Flavia
                    217: 
1.198     brouard   218:   Revision 1.197  2015/09/01 18:24:39  brouard
                    219:   *** empty log message ***
                    220: 
1.197     brouard   221:   Revision 1.196  2015/08/18 23:17:52  brouard
                    222:   Summary: 0.98q5
                    223: 
1.196     brouard   224:   Revision 1.195  2015/08/18 16:28:39  brouard
                    225:   Summary: Adding a hack for testing purpose
                    226: 
                    227:   After reading the title, ftol and model lines, if the comment line has
                    228:   a q, starting with #q, the answer at the end of the run is quit. It
                    229:   permits to run test files in batch with ctest. The former workaround was
                    230:   $ echo q | imach foo.imach
                    231: 
1.195     brouard   232:   Revision 1.194  2015/08/18 13:32:00  brouard
                    233:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    234: 
1.194     brouard   235:   Revision 1.193  2015/08/04 07:17:42  brouard
                    236:   Summary: 0.98q4
                    237: 
1.193     brouard   238:   Revision 1.192  2015/07/16 16:49:02  brouard
                    239:   Summary: Fixing some outputs
                    240: 
1.192     brouard   241:   Revision 1.191  2015/07/14 10:00:33  brouard
                    242:   Summary: Some fixes
                    243: 
1.191     brouard   244:   Revision 1.190  2015/05/05 08:51:13  brouard
                    245:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    246: 
                    247:   Fix 1+age+.
                    248: 
1.190     brouard   249:   Revision 1.189  2015/04/30 14:45:16  brouard
                    250:   Summary: 0.98q2
                    251: 
1.189     brouard   252:   Revision 1.188  2015/04/30 08:27:53  brouard
                    253:   *** empty log message ***
                    254: 
1.188     brouard   255:   Revision 1.187  2015/04/29 09:11:15  brouard
                    256:   *** empty log message ***
                    257: 
1.187     brouard   258:   Revision 1.186  2015/04/23 12:01:52  brouard
                    259:   Summary: V1*age is working now, version 0.98q1
                    260: 
                    261:   Some codes had been disabled in order to simplify and Vn*age was
                    262:   working in the optimization phase, ie, giving correct MLE parameters,
                    263:   but, as usual, outputs were not correct and program core dumped.
                    264: 
1.186     brouard   265:   Revision 1.185  2015/03/11 13:26:42  brouard
                    266:   Summary: Inclusion of compile and links command line for Intel Compiler
                    267: 
1.185     brouard   268:   Revision 1.184  2015/03/11 11:52:39  brouard
                    269:   Summary: Back from Windows 8. Intel Compiler
                    270: 
1.184     brouard   271:   Revision 1.183  2015/03/10 20:34:32  brouard
                    272:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    273: 
                    274:   We use directest instead of original Powell test; probably no
                    275:   incidence on the results, but better justifications;
                    276:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    277:   wrong results.
                    278: 
1.183     brouard   279:   Revision 1.182  2015/02/12 08:19:57  brouard
                    280:   Summary: Trying to keep directest which seems simpler and more general
                    281:   Author: Nicolas Brouard
                    282: 
1.182     brouard   283:   Revision 1.181  2015/02/11 23:22:24  brouard
                    284:   Summary: Comments on Powell added
                    285: 
                    286:   Author:
                    287: 
1.181     brouard   288:   Revision 1.180  2015/02/11 17:33:45  brouard
                    289:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    290: 
1.180     brouard   291:   Revision 1.179  2015/01/04 09:57:06  brouard
                    292:   Summary: back to OS/X
                    293: 
1.179     brouard   294:   Revision 1.178  2015/01/04 09:35:48  brouard
                    295:   *** empty log message ***
                    296: 
1.178     brouard   297:   Revision 1.177  2015/01/03 18:40:56  brouard
                    298:   Summary: Still testing ilc32 on OSX
                    299: 
1.177     brouard   300:   Revision 1.176  2015/01/03 16:45:04  brouard
                    301:   *** empty log message ***
                    302: 
1.176     brouard   303:   Revision 1.175  2015/01/03 16:33:42  brouard
                    304:   *** empty log message ***
                    305: 
1.175     brouard   306:   Revision 1.174  2015/01/03 16:15:49  brouard
                    307:   Summary: Still in cross-compilation
                    308: 
1.174     brouard   309:   Revision 1.173  2015/01/03 12:06:26  brouard
                    310:   Summary: trying to detect cross-compilation
                    311: 
1.173     brouard   312:   Revision 1.172  2014/12/27 12:07:47  brouard
                    313:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    314: 
1.172     brouard   315:   Revision 1.171  2014/12/23 13:26:59  brouard
                    316:   Summary: Back from Visual C
                    317: 
                    318:   Still problem with utsname.h on Windows
                    319: 
1.171     brouard   320:   Revision 1.170  2014/12/23 11:17:12  brouard
                    321:   Summary: Cleaning some \%% back to %%
                    322: 
                    323:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    324: 
1.170     brouard   325:   Revision 1.169  2014/12/22 23:08:31  brouard
                    326:   Summary: 0.98p
                    327: 
                    328:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    329: 
1.169     brouard   330:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   331:   Summary: update
1.169     brouard   332: 
1.168     brouard   333:   Revision 1.167  2014/12/22 13:50:56  brouard
                    334:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    335: 
                    336:   Testing on Linux 64
                    337: 
1.167     brouard   338:   Revision 1.166  2014/12/22 11:40:47  brouard
                    339:   *** empty log message ***
                    340: 
1.166     brouard   341:   Revision 1.165  2014/12/16 11:20:36  brouard
                    342:   Summary: After compiling on Visual C
                    343: 
                    344:   * imach.c (Module): Merging 1.61 to 1.162
                    345: 
1.165     brouard   346:   Revision 1.164  2014/12/16 10:52:11  brouard
                    347:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    348: 
                    349:   * imach.c (Module): Merging 1.61 to 1.162
                    350: 
1.164     brouard   351:   Revision 1.163  2014/12/16 10:30:11  brouard
                    352:   * imach.c (Module): Merging 1.61 to 1.162
                    353: 
1.163     brouard   354:   Revision 1.162  2014/09/25 11:43:39  brouard
                    355:   Summary: temporary backup 0.99!
                    356: 
1.162     brouard   357:   Revision 1.1  2014/09/16 11:06:58  brouard
                    358:   Summary: With some code (wrong) for nlopt
                    359: 
                    360:   Author:
                    361: 
                    362:   Revision 1.161  2014/09/15 20:41:41  brouard
                    363:   Summary: Problem with macro SQR on Intel compiler
                    364: 
1.161     brouard   365:   Revision 1.160  2014/09/02 09:24:05  brouard
                    366:   *** empty log message ***
                    367: 
1.160     brouard   368:   Revision 1.159  2014/09/01 10:34:10  brouard
                    369:   Summary: WIN32
                    370:   Author: Brouard
                    371: 
1.159     brouard   372:   Revision 1.158  2014/08/27 17:11:51  brouard
                    373:   *** empty log message ***
                    374: 
1.158     brouard   375:   Revision 1.157  2014/08/27 16:26:55  brouard
                    376:   Summary: Preparing windows Visual studio version
                    377:   Author: Brouard
                    378: 
                    379:   In order to compile on Visual studio, time.h is now correct and time_t
                    380:   and tm struct should be used. difftime should be used but sometimes I
                    381:   just make the differences in raw time format (time(&now).
                    382:   Trying to suppress #ifdef LINUX
                    383:   Add xdg-open for __linux in order to open default browser.
                    384: 
1.157     brouard   385:   Revision 1.156  2014/08/25 20:10:10  brouard
                    386:   *** empty log message ***
                    387: 
1.156     brouard   388:   Revision 1.155  2014/08/25 18:32:34  brouard
                    389:   Summary: New compile, minor changes
                    390:   Author: Brouard
                    391: 
1.155     brouard   392:   Revision 1.154  2014/06/20 17:32:08  brouard
                    393:   Summary: Outputs now all graphs of convergence to period prevalence
                    394: 
1.154     brouard   395:   Revision 1.153  2014/06/20 16:45:46  brouard
                    396:   Summary: If 3 live state, convergence to period prevalence on same graph
                    397:   Author: Brouard
                    398: 
1.153     brouard   399:   Revision 1.152  2014/06/18 17:54:09  brouard
                    400:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    401: 
1.152     brouard   402:   Revision 1.151  2014/06/18 16:43:30  brouard
                    403:   *** empty log message ***
                    404: 
1.151     brouard   405:   Revision 1.150  2014/06/18 16:42:35  brouard
                    406:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    407:   Author: brouard
                    408: 
1.150     brouard   409:   Revision 1.149  2014/06/18 15:51:14  brouard
                    410:   Summary: Some fixes in parameter files errors
                    411:   Author: Nicolas Brouard
                    412: 
1.149     brouard   413:   Revision 1.148  2014/06/17 17:38:48  brouard
                    414:   Summary: Nothing new
                    415:   Author: Brouard
                    416: 
                    417:   Just a new packaging for OS/X version 0.98nS
                    418: 
1.148     brouard   419:   Revision 1.147  2014/06/16 10:33:11  brouard
                    420:   *** empty log message ***
                    421: 
1.147     brouard   422:   Revision 1.146  2014/06/16 10:20:28  brouard
                    423:   Summary: Merge
                    424:   Author: Brouard
                    425: 
                    426:   Merge, before building revised version.
                    427: 
1.146     brouard   428:   Revision 1.145  2014/06/10 21:23:15  brouard
                    429:   Summary: Debugging with valgrind
                    430:   Author: Nicolas Brouard
                    431: 
                    432:   Lot of changes in order to output the results with some covariates
                    433:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    434:   improve the code.
                    435:   No more memory valgrind error but a lot has to be done in order to
                    436:   continue the work of splitting the code into subroutines.
                    437:   Also, decodemodel has been improved. Tricode is still not
                    438:   optimal. nbcode should be improved. Documentation has been added in
                    439:   the source code.
                    440: 
1.144     brouard   441:   Revision 1.143  2014/01/26 09:45:38  brouard
                    442:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    443: 
                    444:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    445:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    446: 
1.143     brouard   447:   Revision 1.142  2014/01/26 03:57:36  brouard
                    448:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    449: 
                    450:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    451: 
1.142     brouard   452:   Revision 1.141  2014/01/26 02:42:01  brouard
                    453:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    454: 
1.141     brouard   455:   Revision 1.140  2011/09/02 10:37:54  brouard
                    456:   Summary: times.h is ok with mingw32 now.
                    457: 
1.140     brouard   458:   Revision 1.139  2010/06/14 07:50:17  brouard
                    459:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    460:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    461: 
1.139     brouard   462:   Revision 1.138  2010/04/30 18:19:40  brouard
                    463:   *** empty log message ***
                    464: 
1.138     brouard   465:   Revision 1.137  2010/04/29 18:11:38  brouard
                    466:   (Module): Checking covariates for more complex models
                    467:   than V1+V2. A lot of change to be done. Unstable.
                    468: 
1.137     brouard   469:   Revision 1.136  2010/04/26 20:30:53  brouard
                    470:   (Module): merging some libgsl code. Fixing computation
                    471:   of likelione (using inter/intrapolation if mle = 0) in order to
                    472:   get same likelihood as if mle=1.
                    473:   Some cleaning of code and comments added.
                    474: 
1.136     brouard   475:   Revision 1.135  2009/10/29 15:33:14  brouard
                    476:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    477: 
1.135     brouard   478:   Revision 1.134  2009/10/29 13:18:53  brouard
                    479:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    480: 
1.134     brouard   481:   Revision 1.133  2009/07/06 10:21:25  brouard
                    482:   just nforces
                    483: 
1.133     brouard   484:   Revision 1.132  2009/07/06 08:22:05  brouard
                    485:   Many tings
                    486: 
1.132     brouard   487:   Revision 1.131  2009/06/20 16:22:47  brouard
                    488:   Some dimensions resccaled
                    489: 
1.131     brouard   490:   Revision 1.130  2009/05/26 06:44:34  brouard
                    491:   (Module): Max Covariate is now set to 20 instead of 8. A
                    492:   lot of cleaning with variables initialized to 0. Trying to make
                    493:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    494: 
1.130     brouard   495:   Revision 1.129  2007/08/31 13:49:27  lievre
                    496:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    497: 
1.129     lievre    498:   Revision 1.128  2006/06/30 13:02:05  brouard
                    499:   (Module): Clarifications on computing e.j
                    500: 
1.128     brouard   501:   Revision 1.127  2006/04/28 18:11:50  brouard
                    502:   (Module): Yes the sum of survivors was wrong since
                    503:   imach-114 because nhstepm was no more computed in the age
                    504:   loop. Now we define nhstepma in the age loop.
                    505:   (Module): In order to speed up (in case of numerous covariates) we
                    506:   compute health expectancies (without variances) in a first step
                    507:   and then all the health expectancies with variances or standard
                    508:   deviation (needs data from the Hessian matrices) which slows the
                    509:   computation.
                    510:   In the future we should be able to stop the program is only health
                    511:   expectancies and graph are needed without standard deviations.
                    512: 
1.127     brouard   513:   Revision 1.126  2006/04/28 17:23:28  brouard
                    514:   (Module): Yes the sum of survivors was wrong since
                    515:   imach-114 because nhstepm was no more computed in the age
                    516:   loop. Now we define nhstepma in the age loop.
                    517:   Version 0.98h
                    518: 
1.126     brouard   519:   Revision 1.125  2006/04/04 15:20:31  lievre
                    520:   Errors in calculation of health expectancies. Age was not initialized.
                    521:   Forecasting file added.
                    522: 
                    523:   Revision 1.124  2006/03/22 17:13:53  lievre
                    524:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    525:   The log-likelihood is printed in the log file
                    526: 
                    527:   Revision 1.123  2006/03/20 10:52:43  brouard
                    528:   * imach.c (Module): <title> changed, corresponds to .htm file
                    529:   name. <head> headers where missing.
                    530: 
                    531:   * imach.c (Module): Weights can have a decimal point as for
                    532:   English (a comma might work with a correct LC_NUMERIC environment,
                    533:   otherwise the weight is truncated).
                    534:   Modification of warning when the covariates values are not 0 or
                    535:   1.
                    536:   Version 0.98g
                    537: 
                    538:   Revision 1.122  2006/03/20 09:45:41  brouard
                    539:   (Module): Weights can have a decimal point as for
                    540:   English (a comma might work with a correct LC_NUMERIC environment,
                    541:   otherwise the weight is truncated).
                    542:   Modification of warning when the covariates values are not 0 or
                    543:   1.
                    544:   Version 0.98g
                    545: 
                    546:   Revision 1.121  2006/03/16 17:45:01  lievre
                    547:   * imach.c (Module): Comments concerning covariates added
                    548: 
                    549:   * imach.c (Module): refinements in the computation of lli if
                    550:   status=-2 in order to have more reliable computation if stepm is
                    551:   not 1 month. Version 0.98f
                    552: 
                    553:   Revision 1.120  2006/03/16 15:10:38  lievre
                    554:   (Module): refinements in the computation of lli if
                    555:   status=-2 in order to have more reliable computation if stepm is
                    556:   not 1 month. Version 0.98f
                    557: 
                    558:   Revision 1.119  2006/03/15 17:42:26  brouard
                    559:   (Module): Bug if status = -2, the loglikelihood was
                    560:   computed as likelihood omitting the logarithm. Version O.98e
                    561: 
                    562:   Revision 1.118  2006/03/14 18:20:07  brouard
                    563:   (Module): varevsij Comments added explaining the second
                    564:   table of variances if popbased=1 .
                    565:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    566:   (Module): Function pstamp added
                    567:   (Module): Version 0.98d
                    568: 
                    569:   Revision 1.117  2006/03/14 17:16:22  brouard
                    570:   (Module): varevsij Comments added explaining the second
                    571:   table of variances if popbased=1 .
                    572:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    573:   (Module): Function pstamp added
                    574:   (Module): Version 0.98d
                    575: 
                    576:   Revision 1.116  2006/03/06 10:29:27  brouard
                    577:   (Module): Variance-covariance wrong links and
                    578:   varian-covariance of ej. is needed (Saito).
                    579: 
                    580:   Revision 1.115  2006/02/27 12:17:45  brouard
                    581:   (Module): One freematrix added in mlikeli! 0.98c
                    582: 
                    583:   Revision 1.114  2006/02/26 12:57:58  brouard
                    584:   (Module): Some improvements in processing parameter
                    585:   filename with strsep.
                    586: 
                    587:   Revision 1.113  2006/02/24 14:20:24  brouard
                    588:   (Module): Memory leaks checks with valgrind and:
                    589:   datafile was not closed, some imatrix were not freed and on matrix
                    590:   allocation too.
                    591: 
                    592:   Revision 1.112  2006/01/30 09:55:26  brouard
                    593:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    594: 
                    595:   Revision 1.111  2006/01/25 20:38:18  brouard
                    596:   (Module): Lots of cleaning and bugs added (Gompertz)
                    597:   (Module): Comments can be added in data file. Missing date values
                    598:   can be a simple dot '.'.
                    599: 
                    600:   Revision 1.110  2006/01/25 00:51:50  brouard
                    601:   (Module): Lots of cleaning and bugs added (Gompertz)
                    602: 
                    603:   Revision 1.109  2006/01/24 19:37:15  brouard
                    604:   (Module): Comments (lines starting with a #) are allowed in data.
                    605: 
                    606:   Revision 1.108  2006/01/19 18:05:42  lievre
                    607:   Gnuplot problem appeared...
                    608:   To be fixed
                    609: 
                    610:   Revision 1.107  2006/01/19 16:20:37  brouard
                    611:   Test existence of gnuplot in imach path
                    612: 
                    613:   Revision 1.106  2006/01/19 13:24:36  brouard
                    614:   Some cleaning and links added in html output
                    615: 
                    616:   Revision 1.105  2006/01/05 20:23:19  lievre
                    617:   *** empty log message ***
                    618: 
                    619:   Revision 1.104  2005/09/30 16:11:43  lievre
                    620:   (Module): sump fixed, loop imx fixed, and simplifications.
                    621:   (Module): If the status is missing at the last wave but we know
                    622:   that the person is alive, then we can code his/her status as -2
                    623:   (instead of missing=-1 in earlier versions) and his/her
                    624:   contributions to the likelihood is 1 - Prob of dying from last
                    625:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    626:   the healthy state at last known wave). Version is 0.98
                    627: 
                    628:   Revision 1.103  2005/09/30 15:54:49  lievre
                    629:   (Module): sump fixed, loop imx fixed, and simplifications.
                    630: 
                    631:   Revision 1.102  2004/09/15 17:31:30  brouard
                    632:   Add the possibility to read data file including tab characters.
                    633: 
                    634:   Revision 1.101  2004/09/15 10:38:38  brouard
                    635:   Fix on curr_time
                    636: 
                    637:   Revision 1.100  2004/07/12 18:29:06  brouard
                    638:   Add version for Mac OS X. Just define UNIX in Makefile
                    639: 
                    640:   Revision 1.99  2004/06/05 08:57:40  brouard
                    641:   *** empty log message ***
                    642: 
                    643:   Revision 1.98  2004/05/16 15:05:56  brouard
                    644:   New version 0.97 . First attempt to estimate force of mortality
                    645:   directly from the data i.e. without the need of knowing the health
                    646:   state at each age, but using a Gompertz model: log u =a + b*age .
                    647:   This is the basic analysis of mortality and should be done before any
                    648:   other analysis, in order to test if the mortality estimated from the
                    649:   cross-longitudinal survey is different from the mortality estimated
                    650:   from other sources like vital statistic data.
                    651: 
                    652:   The same imach parameter file can be used but the option for mle should be -3.
                    653: 
1.133     brouard   654:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   655:   former routines in order to include the new code within the former code.
                    656: 
                    657:   The output is very simple: only an estimate of the intercept and of
                    658:   the slope with 95% confident intervals.
                    659: 
                    660:   Current limitations:
                    661:   A) Even if you enter covariates, i.e. with the
                    662:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    663:   B) There is no computation of Life Expectancy nor Life Table.
                    664: 
                    665:   Revision 1.97  2004/02/20 13:25:42  lievre
                    666:   Version 0.96d. Population forecasting command line is (temporarily)
                    667:   suppressed.
                    668: 
                    669:   Revision 1.96  2003/07/15 15:38:55  brouard
                    670:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    671:   rewritten within the same printf. Workaround: many printfs.
                    672: 
                    673:   Revision 1.95  2003/07/08 07:54:34  brouard
                    674:   * imach.c (Repository):
                    675:   (Repository): Using imachwizard code to output a more meaningful covariance
                    676:   matrix (cov(a12,c31) instead of numbers.
                    677: 
                    678:   Revision 1.94  2003/06/27 13:00:02  brouard
                    679:   Just cleaning
                    680: 
                    681:   Revision 1.93  2003/06/25 16:33:55  brouard
                    682:   (Module): On windows (cygwin) function asctime_r doesn't
                    683:   exist so I changed back to asctime which exists.
                    684:   (Module): Version 0.96b
                    685: 
                    686:   Revision 1.92  2003/06/25 16:30:45  brouard
                    687:   (Module): On windows (cygwin) function asctime_r doesn't
                    688:   exist so I changed back to asctime which exists.
                    689: 
                    690:   Revision 1.91  2003/06/25 15:30:29  brouard
                    691:   * imach.c (Repository): Duplicated warning errors corrected.
                    692:   (Repository): Elapsed time after each iteration is now output. It
                    693:   helps to forecast when convergence will be reached. Elapsed time
                    694:   is stamped in powell.  We created a new html file for the graphs
                    695:   concerning matrix of covariance. It has extension -cov.htm.
                    696: 
                    697:   Revision 1.90  2003/06/24 12:34:15  brouard
                    698:   (Module): Some bugs corrected for windows. Also, when
                    699:   mle=-1 a template is output in file "or"mypar.txt with the design
                    700:   of the covariance matrix to be input.
                    701: 
                    702:   Revision 1.89  2003/06/24 12:30:52  brouard
                    703:   (Module): Some bugs corrected for windows. Also, when
                    704:   mle=-1 a template is output in file "or"mypar.txt with the design
                    705:   of the covariance matrix to be input.
                    706: 
                    707:   Revision 1.88  2003/06/23 17:54:56  brouard
                    708:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    709: 
                    710:   Revision 1.87  2003/06/18 12:26:01  brouard
                    711:   Version 0.96
                    712: 
                    713:   Revision 1.86  2003/06/17 20:04:08  brouard
                    714:   (Module): Change position of html and gnuplot routines and added
                    715:   routine fileappend.
                    716: 
                    717:   Revision 1.85  2003/06/17 13:12:43  brouard
                    718:   * imach.c (Repository): Check when date of death was earlier that
                    719:   current date of interview. It may happen when the death was just
                    720:   prior to the death. In this case, dh was negative and likelihood
                    721:   was wrong (infinity). We still send an "Error" but patch by
                    722:   assuming that the date of death was just one stepm after the
                    723:   interview.
                    724:   (Repository): Because some people have very long ID (first column)
                    725:   we changed int to long in num[] and we added a new lvector for
                    726:   memory allocation. But we also truncated to 8 characters (left
                    727:   truncation)
                    728:   (Repository): No more line truncation errors.
                    729: 
                    730:   Revision 1.84  2003/06/13 21:44:43  brouard
                    731:   * imach.c (Repository): Replace "freqsummary" at a correct
                    732:   place. It differs from routine "prevalence" which may be called
                    733:   many times. Probs is memory consuming and must be used with
                    734:   parcimony.
                    735:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    736: 
                    737:   Revision 1.83  2003/06/10 13:39:11  lievre
                    738:   *** empty log message ***
                    739: 
                    740:   Revision 1.82  2003/06/05 15:57:20  brouard
                    741:   Add log in  imach.c and  fullversion number is now printed.
                    742: 
                    743: */
                    744: /*
                    745:    Interpolated Markov Chain
                    746: 
                    747:   Short summary of the programme:
                    748:   
1.227     brouard   749:   This program computes Healthy Life Expectancies or State-specific
                    750:   (if states aren't health statuses) Expectancies from
                    751:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    752: 
                    753:   -1- a first survey ("cross") where individuals from different ages
                    754:   are interviewed on their health status or degree of disability (in
                    755:   the case of a health survey which is our main interest)
                    756: 
                    757:   -2- at least a second wave of interviews ("longitudinal") which
                    758:   measure each change (if any) in individual health status.  Health
                    759:   expectancies are computed from the time spent in each health state
                    760:   according to a model. More health states you consider, more time is
                    761:   necessary to reach the Maximum Likelihood of the parameters involved
                    762:   in the model.  The simplest model is the multinomial logistic model
                    763:   where pij is the probability to be observed in state j at the second
                    764:   wave conditional to be observed in state i at the first
                    765:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    766:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    767:   have a more complex model than "constant and age", you should modify
                    768:   the program where the markup *Covariates have to be included here
                    769:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   770:   convergence.
                    771: 
                    772:   The advantage of this computer programme, compared to a simple
                    773:   multinomial logistic model, is clear when the delay between waves is not
                    774:   identical for each individual. Also, if a individual missed an
                    775:   intermediate interview, the information is lost, but taken into
                    776:   account using an interpolation or extrapolation.  
                    777: 
                    778:   hPijx is the probability to be observed in state i at age x+h
                    779:   conditional to the observed state i at age x. The delay 'h' can be
                    780:   split into an exact number (nh*stepm) of unobserved intermediate
                    781:   states. This elementary transition (by month, quarter,
                    782:   semester or year) is modelled as a multinomial logistic.  The hPx
                    783:   matrix is simply the matrix product of nh*stepm elementary matrices
                    784:   and the contribution of each individual to the likelihood is simply
                    785:   hPijx.
                    786: 
                    787:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   788:   of the life expectancies. It also computes the period (stable) prevalence.
                    789: 
                    790: Back prevalence and projections:
1.227     brouard   791: 
                    792:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    793:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    794:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    795:    mobilavproj)
                    796: 
                    797:     Computes the back prevalence limit for any combination of
                    798:     covariate values k at any age between ageminpar and agemaxpar and
                    799:     returns it in **bprlim. In the loops,
                    800: 
                    801:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    802:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    803: 
                    804:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   805:    Computes for any combination of covariates k and any age between bage and fage 
                    806:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    807:                        oldm=oldms;savm=savms;
1.227     brouard   808: 
                    809:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);
1.218     brouard   810:      Computes the transition matrix starting at age 'age' over
                    811:      'nhstepm*hstepm*stepm' months (i.e. until
                    812:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   813:      nhstepm*hstepm matrices. 
                    814: 
                    815:      Returns p3mat[i][j][h] after calling
                    816:      p3mat[i][j][h]=matprod2(newm,
                    817:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    818:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    819:      oldm);
1.226     brouard   820: 
                    821: Important routines
                    822: 
                    823: - func (or funcone), computes logit (pij) distinguishing
                    824:   o fixed variables (single or product dummies or quantitative);
                    825:   o varying variables by:
                    826:    (1) wave (single, product dummies, quantitative), 
                    827:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    828:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    829:        % varying dummy (not done) or quantitative (not done);
                    830: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    831:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    832: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    833:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    834:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   835: 
1.226     brouard   836: 
                    837:   
1.133     brouard   838:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    839:            Institut national d'études démographiques, Paris.
1.126     brouard   840:   This software have been partly granted by Euro-REVES, a concerted action
                    841:   from the European Union.
                    842:   It is copyrighted identically to a GNU software product, ie programme and
                    843:   software can be distributed freely for non commercial use. Latest version
                    844:   can be accessed at http://euroreves.ined.fr/imach .
                    845: 
                    846:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    847:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    848:   
                    849:   **********************************************************************/
                    850: /*
                    851:   main
                    852:   read parameterfile
                    853:   read datafile
                    854:   concatwav
                    855:   freqsummary
                    856:   if (mle >= 1)
                    857:     mlikeli
                    858:   print results files
                    859:   if mle==1 
                    860:      computes hessian
                    861:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    862:       begin-prev-date,...
                    863:   open gnuplot file
                    864:   open html file
1.145     brouard   865:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    866:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    867:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    868:     freexexit2 possible for memory heap.
                    869: 
                    870:   h Pij x                         | pij_nom  ficrestpij
                    871:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    872:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    873:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    874: 
                    875:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    876:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    877:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    878:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    879:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    880: 
1.126     brouard   881:   forecasting if prevfcast==1 prevforecast call prevalence()
                    882:   health expectancies
                    883:   Variance-covariance of DFLE
                    884:   prevalence()
                    885:    movingaverage()
                    886:   varevsij() 
                    887:   if popbased==1 varevsij(,popbased)
                    888:   total life expectancies
                    889:   Variance of period (stable) prevalence
                    890:  end
                    891: */
                    892: 
1.187     brouard   893: /* #define DEBUG */
                    894: /* #define DEBUGBRENT */
1.203     brouard   895: /* #define DEBUGLINMIN */
                    896: /* #define DEBUGHESS */
                    897: #define DEBUGHESSIJ
1.224     brouard   898: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   899: #define POWELL /* Instead of NLOPT */
1.224     brouard   900: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   901: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    902: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   903: 
                    904: #include <math.h>
                    905: #include <stdio.h>
                    906: #include <stdlib.h>
                    907: #include <string.h>
1.226     brouard   908: #include <ctype.h>
1.159     brouard   909: 
                    910: #ifdef _WIN32
                    911: #include <io.h>
1.172     brouard   912: #include <windows.h>
                    913: #include <tchar.h>
1.159     brouard   914: #else
1.126     brouard   915: #include <unistd.h>
1.159     brouard   916: #endif
1.126     brouard   917: 
                    918: #include <limits.h>
                    919: #include <sys/types.h>
1.171     brouard   920: 
                    921: #if defined(__GNUC__)
                    922: #include <sys/utsname.h> /* Doesn't work on Windows */
                    923: #endif
                    924: 
1.126     brouard   925: #include <sys/stat.h>
                    926: #include <errno.h>
1.159     brouard   927: /* extern int errno; */
1.126     brouard   928: 
1.157     brouard   929: /* #ifdef LINUX */
                    930: /* #include <time.h> */
                    931: /* #include "timeval.h" */
                    932: /* #else */
                    933: /* #include <sys/time.h> */
                    934: /* #endif */
                    935: 
1.126     brouard   936: #include <time.h>
                    937: 
1.136     brouard   938: #ifdef GSL
                    939: #include <gsl/gsl_errno.h>
                    940: #include <gsl/gsl_multimin.h>
                    941: #endif
                    942: 
1.167     brouard   943: 
1.162     brouard   944: #ifdef NLOPT
                    945: #include <nlopt.h>
                    946: typedef struct {
                    947:   double (* function)(double [] );
                    948: } myfunc_data ;
                    949: #endif
                    950: 
1.126     brouard   951: /* #include <libintl.h> */
                    952: /* #define _(String) gettext (String) */
                    953: 
1.251     brouard   954: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   955: 
                    956: #define GNUPLOTPROGRAM "gnuplot"
                    957: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    958: #define FILENAMELENGTH 132
                    959: 
                    960: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    961: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    962: 
1.144     brouard   963: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    964: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   965: 
                    966: #define NINTERVMAX 8
1.144     brouard   967: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    968: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    969: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   970: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   971: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    972: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   973: #define MAXN 20000
1.144     brouard   974: #define YEARM 12. /**< Number of months per year */
1.218     brouard   975: /* #define AGESUP 130 */
                    976: #define AGESUP 150
                    977: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   978: #define AGEBASE 40
1.194     brouard   979: #define AGEOVERFLOW 1.e20
1.164     brouard   980: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard   981: #ifdef _WIN32
                    982: #define DIRSEPARATOR '\\'
                    983: #define CHARSEPARATOR "\\"
                    984: #define ODIRSEPARATOR '/'
                    985: #else
1.126     brouard   986: #define DIRSEPARATOR '/'
                    987: #define CHARSEPARATOR "/"
                    988: #define ODIRSEPARATOR '\\'
                    989: #endif
                    990: 
1.263   ! brouard   991: /* $Id: imach.c,v 1.262 2017/04/18 16:48:12 brouard Exp $ */
1.126     brouard   992: /* $State: Exp $ */
1.196     brouard   993: #include "version.h"
                    994: char version[]=__IMACH_VERSION__;
1.224     brouard   995: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.263   ! brouard   996: char fullversion[]="$Revision: 1.262 $ $Date: 2017/04/18 16:48:12 $"; 
1.126     brouard   997: char strstart[80];
                    998: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard   999: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1000: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1001: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1002: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1003: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1004: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1005: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1006: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1007: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1008: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1009: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1010: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1011: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1012: int nsd=0; /**< Total number of single dummy variables (output) */
                   1013: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1014: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1015: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1016: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1017: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1018: int cptcov=0; /* Working variable */
1.218     brouard  1019: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1020: int npar=NPARMAX;
                   1021: int nlstate=2; /* Number of live states */
                   1022: int ndeath=1; /* Number of dead states */
1.130     brouard  1023: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1024: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1025: int popbased=0;
                   1026: 
                   1027: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1028: int maxwav=0; /* Maxim number of waves */
                   1029: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1030: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1031: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1032:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1033: int mle=1, weightopt=0;
1.126     brouard  1034: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1035: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1036: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1037:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1038: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1039: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1040: 
1.130     brouard  1041: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1042: double **matprod2(); /* test */
1.126     brouard  1043: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1044: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1045: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1046: 
1.136     brouard  1047: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1048: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1049: FILE *ficlog, *ficrespow;
1.130     brouard  1050: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1051: double fretone; /* Only one call to likelihood */
1.130     brouard  1052: long ipmx=0; /* Number of contributions */
1.126     brouard  1053: double sw; /* Sum of weights */
                   1054: char filerespow[FILENAMELENGTH];
                   1055: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1056: FILE *ficresilk;
                   1057: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1058: FILE *ficresprobmorprev;
                   1059: FILE *fichtm, *fichtmcov; /* Html File */
                   1060: FILE *ficreseij;
                   1061: char filerese[FILENAMELENGTH];
                   1062: FILE *ficresstdeij;
                   1063: char fileresstde[FILENAMELENGTH];
                   1064: FILE *ficrescveij;
                   1065: char filerescve[FILENAMELENGTH];
                   1066: FILE  *ficresvij;
                   1067: char fileresv[FILENAMELENGTH];
                   1068: FILE  *ficresvpl;
                   1069: char fileresvpl[FILENAMELENGTH];
                   1070: char title[MAXLINE];
1.234     brouard  1071: char model[MAXLINE]; /**< The model line */
1.217     brouard  1072: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1073: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1074: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1075: char command[FILENAMELENGTH];
                   1076: int  outcmd=0;
                   1077: 
1.217     brouard  1078: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1079: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1080: char filelog[FILENAMELENGTH]; /* Log file */
                   1081: char filerest[FILENAMELENGTH];
                   1082: char fileregp[FILENAMELENGTH];
                   1083: char popfile[FILENAMELENGTH];
                   1084: 
                   1085: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1086: 
1.157     brouard  1087: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1088: /* struct timezone tzp; */
                   1089: /* extern int gettimeofday(); */
                   1090: struct tm tml, *gmtime(), *localtime();
                   1091: 
                   1092: extern time_t time();
                   1093: 
                   1094: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1095: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1096: struct tm tm;
                   1097: 
1.126     brouard  1098: char strcurr[80], strfor[80];
                   1099: 
                   1100: char *endptr;
                   1101: long lval;
                   1102: double dval;
                   1103: 
                   1104: #define NR_END 1
                   1105: #define FREE_ARG char*
                   1106: #define FTOL 1.0e-10
                   1107: 
                   1108: #define NRANSI 
1.240     brouard  1109: #define ITMAX 200
                   1110: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1111: 
                   1112: #define TOL 2.0e-4 
                   1113: 
                   1114: #define CGOLD 0.3819660 
                   1115: #define ZEPS 1.0e-10 
                   1116: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1117: 
                   1118: #define GOLD 1.618034 
                   1119: #define GLIMIT 100.0 
                   1120: #define TINY 1.0e-20 
                   1121: 
                   1122: static double maxarg1,maxarg2;
                   1123: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1124: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1125:   
                   1126: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1127: #define rint(a) floor(a+0.5)
1.166     brouard  1128: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1129: #define mytinydouble 1.0e-16
1.166     brouard  1130: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1131: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1132: /* static double dsqrarg; */
                   1133: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1134: static double sqrarg;
                   1135: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1136: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1137: int agegomp= AGEGOMP;
                   1138: 
                   1139: int imx; 
                   1140: int stepm=1;
                   1141: /* Stepm, step in month: minimum step interpolation*/
                   1142: 
                   1143: int estepm;
                   1144: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1145: 
                   1146: int m,nb;
                   1147: long *num;
1.197     brouard  1148: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1149: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1150:                   covariate for which somebody answered excluding 
                   1151:                   undefined. Usually 2: 0 and 1. */
                   1152: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1153:                             covariate for which somebody answered including 
                   1154:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1155: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1156: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1157: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1158: double *ageexmed,*agecens;
                   1159: double dateintmean=0;
                   1160: 
                   1161: double *weight;
                   1162: int **s; /* Status */
1.141     brouard  1163: double *agedc;
1.145     brouard  1164: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1165:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1166:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.225     brouard  1167: double **coqvar; /* Fixed quantitative covariate iqv */
                   1168: double ***cotvar; /* Time varying covariate itv */
                   1169: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1170: double  idx; 
                   1171: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1172: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1173: /*k          1  2   3   4     5    6    7     8    9 */
                   1174: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1175: /* Tndvar[k]    1   2   3               4          5 */
                   1176: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1177: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1178: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1179: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1180: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1181: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1182: /* Tprod[i]=k           4               7            */
                   1183: /* Tage[i]=k                  5               8      */
                   1184: /* */
                   1185: /* Type                    */
                   1186: /* V         1  2  3  4  5 */
                   1187: /*           F  F  V  V  V */
                   1188: /*           D  Q  D  D  Q */
                   1189: /*                         */
                   1190: int *TvarsD;
                   1191: int *TvarsDind;
                   1192: int *TvarsQ;
                   1193: int *TvarsQind;
                   1194: 
1.235     brouard  1195: #define MAXRESULTLINES 10
                   1196: int nresult=0;
1.258     brouard  1197: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1198: int TKresult[MAXRESULTLINES];
1.237     brouard  1199: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1200: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1201: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1202: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1203: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1204: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1205: 
1.234     brouard  1206: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1207: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1208: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1209: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1210: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1211: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1212: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1213: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1214: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1215: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1216: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1217: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1218: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1219: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1220: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1221: 
1.230     brouard  1222: int *Tvarsel; /**< Selected covariates for output */
                   1223: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1224: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1225: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1226: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1227: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1228: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1229: int *Tage;
1.227     brouard  1230: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1231: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1232: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1233: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1234: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1235: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1236: int **Tvard;
                   1237: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1238: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1239: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1240:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1241:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1242: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1243: double *lsurv, *lpop, *tpop;
                   1244: 
1.231     brouard  1245: #define FD 1; /* Fixed dummy covariate */
                   1246: #define FQ 2; /* Fixed quantitative covariate */
                   1247: #define FP 3; /* Fixed product covariate */
                   1248: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1249: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1250: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1251: #define VD 10; /* Varying dummy covariate */
                   1252: #define VQ 11; /* Varying quantitative covariate */
                   1253: #define VP 12; /* Varying product covariate */
                   1254: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1255: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1256: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1257: #define APFD 16; /* Age product * fixed dummy covariate */
                   1258: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1259: #define APVD 18; /* Age product * varying dummy covariate */
                   1260: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1261: 
                   1262: #define FTYPE 1; /* Fixed covariate */
                   1263: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1264: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1265: 
                   1266: struct kmodel{
                   1267:        int maintype; /* main type */
                   1268:        int subtype; /* subtype */
                   1269: };
                   1270: struct kmodel modell[NCOVMAX];
                   1271: 
1.143     brouard  1272: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1273: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1274: 
                   1275: /**************** split *************************/
                   1276: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1277: {
                   1278:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1279:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1280:   */ 
                   1281:   char *ss;                            /* pointer */
1.186     brouard  1282:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1283: 
                   1284:   l1 = strlen(path );                  /* length of path */
                   1285:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1286:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1287:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1288:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1289:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1290:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1291:     /* get current working directory */
                   1292:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1293: #ifdef WIN32
                   1294:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1295: #else
                   1296:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1297: #endif
1.126     brouard  1298:       return( GLOCK_ERROR_GETCWD );
                   1299:     }
                   1300:     /* got dirc from getcwd*/
                   1301:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1302:   } else {                             /* strip directory from path */
1.126     brouard  1303:     ss++;                              /* after this, the filename */
                   1304:     l2 = strlen( ss );                 /* length of filename */
                   1305:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1306:     strcpy( name, ss );                /* save file name */
                   1307:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1308:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1309:     printf(" DIRC2 = %s \n",dirc);
                   1310:   }
                   1311:   /* We add a separator at the end of dirc if not exists */
                   1312:   l1 = strlen( dirc );                 /* length of directory */
                   1313:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1314:     dirc[l1] =  DIRSEPARATOR;
                   1315:     dirc[l1+1] = 0; 
                   1316:     printf(" DIRC3 = %s \n",dirc);
                   1317:   }
                   1318:   ss = strrchr( name, '.' );           /* find last / */
                   1319:   if (ss >0){
                   1320:     ss++;
                   1321:     strcpy(ext,ss);                    /* save extension */
                   1322:     l1= strlen( name);
                   1323:     l2= strlen(ss)+1;
                   1324:     strncpy( finame, name, l1-l2);
                   1325:     finame[l1-l2]= 0;
                   1326:   }
                   1327: 
                   1328:   return( 0 );                         /* we're done */
                   1329: }
                   1330: 
                   1331: 
                   1332: /******************************************/
                   1333: 
                   1334: void replace_back_to_slash(char *s, char*t)
                   1335: {
                   1336:   int i;
                   1337:   int lg=0;
                   1338:   i=0;
                   1339:   lg=strlen(t);
                   1340:   for(i=0; i<= lg; i++) {
                   1341:     (s[i] = t[i]);
                   1342:     if (t[i]== '\\') s[i]='/';
                   1343:   }
                   1344: }
                   1345: 
1.132     brouard  1346: char *trimbb(char *out, char *in)
1.137     brouard  1347: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1348:   char *s;
                   1349:   s=out;
                   1350:   while (*in != '\0'){
1.137     brouard  1351:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1352:       in++;
                   1353:     }
                   1354:     *out++ = *in++;
                   1355:   }
                   1356:   *out='\0';
                   1357:   return s;
                   1358: }
                   1359: 
1.187     brouard  1360: /* char *substrchaine(char *out, char *in, char *chain) */
                   1361: /* { */
                   1362: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1363: /*   char *s, *t; */
                   1364: /*   t=in;s=out; */
                   1365: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1366: /*     *out++ = *in++; */
                   1367: /*   } */
                   1368: 
                   1369: /*   /\* *in matches *chain *\/ */
                   1370: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1371: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1372: /*   } */
                   1373: /*   in--; chain--; */
                   1374: /*   while ( (*in != '\0')){ */
                   1375: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1376: /*     *out++ = *in++; */
                   1377: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1378: /*   } */
                   1379: /*   *out='\0'; */
                   1380: /*   out=s; */
                   1381: /*   return out; */
                   1382: /* } */
                   1383: char *substrchaine(char *out, char *in, char *chain)
                   1384: {
                   1385:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1386:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1387: 
                   1388:   char *strloc;
                   1389: 
                   1390:   strcpy (out, in); 
                   1391:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1392:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1393:   if(strloc != NULL){ 
                   1394:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1395:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1396:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1397:   }
                   1398:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1399:   return out;
                   1400: }
                   1401: 
                   1402: 
1.145     brouard  1403: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1404: {
1.187     brouard  1405:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1406:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1407:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1408:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1409:   */
1.160     brouard  1410:   char *s, *t;
1.145     brouard  1411:   t=in;s=in;
                   1412:   while ((*in != occ) && (*in != '\0')){
                   1413:     *alocc++ = *in++;
                   1414:   }
                   1415:   if( *in == occ){
                   1416:     *(alocc)='\0';
                   1417:     s=++in;
                   1418:   }
                   1419:  
                   1420:   if (s == t) {/* occ not found */
                   1421:     *(alocc-(in-s))='\0';
                   1422:     in=s;
                   1423:   }
                   1424:   while ( *in != '\0'){
                   1425:     *blocc++ = *in++;
                   1426:   }
                   1427: 
                   1428:   *blocc='\0';
                   1429:   return t;
                   1430: }
1.137     brouard  1431: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1432: {
1.187     brouard  1433:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1434:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1435:      gives blocc="abcdef2ghi" and alocc="j".
                   1436:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1437:   */
                   1438:   char *s, *t;
                   1439:   t=in;s=in;
                   1440:   while (*in != '\0'){
                   1441:     while( *in == occ){
                   1442:       *blocc++ = *in++;
                   1443:       s=in;
                   1444:     }
                   1445:     *blocc++ = *in++;
                   1446:   }
                   1447:   if (s == t) /* occ not found */
                   1448:     *(blocc-(in-s))='\0';
                   1449:   else
                   1450:     *(blocc-(in-s)-1)='\0';
                   1451:   in=s;
                   1452:   while ( *in != '\0'){
                   1453:     *alocc++ = *in++;
                   1454:   }
                   1455: 
                   1456:   *alocc='\0';
                   1457:   return s;
                   1458: }
                   1459: 
1.126     brouard  1460: int nbocc(char *s, char occ)
                   1461: {
                   1462:   int i,j=0;
                   1463:   int lg=20;
                   1464:   i=0;
                   1465:   lg=strlen(s);
                   1466:   for(i=0; i<= lg; i++) {
1.234     brouard  1467:     if  (s[i] == occ ) j++;
1.126     brouard  1468:   }
                   1469:   return j;
                   1470: }
                   1471: 
1.137     brouard  1472: /* void cutv(char *u,char *v, char*t, char occ) */
                   1473: /* { */
                   1474: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1475: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1476: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1477: /*   int i,lg,j,p=0; */
                   1478: /*   i=0; */
                   1479: /*   lg=strlen(t); */
                   1480: /*   for(j=0; j<=lg-1; j++) { */
                   1481: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1482: /*   } */
1.126     brouard  1483: 
1.137     brouard  1484: /*   for(j=0; j<p; j++) { */
                   1485: /*     (u[j] = t[j]); */
                   1486: /*   } */
                   1487: /*      u[p]='\0'; */
1.126     brouard  1488: 
1.137     brouard  1489: /*    for(j=0; j<= lg; j++) { */
                   1490: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1491: /*   } */
                   1492: /* } */
1.126     brouard  1493: 
1.160     brouard  1494: #ifdef _WIN32
                   1495: char * strsep(char **pp, const char *delim)
                   1496: {
                   1497:   char *p, *q;
                   1498:          
                   1499:   if ((p = *pp) == NULL)
                   1500:     return 0;
                   1501:   if ((q = strpbrk (p, delim)) != NULL)
                   1502:   {
                   1503:     *pp = q + 1;
                   1504:     *q = '\0';
                   1505:   }
                   1506:   else
                   1507:     *pp = 0;
                   1508:   return p;
                   1509: }
                   1510: #endif
                   1511: 
1.126     brouard  1512: /********************** nrerror ********************/
                   1513: 
                   1514: void nrerror(char error_text[])
                   1515: {
                   1516:   fprintf(stderr,"ERREUR ...\n");
                   1517:   fprintf(stderr,"%s\n",error_text);
                   1518:   exit(EXIT_FAILURE);
                   1519: }
                   1520: /*********************** vector *******************/
                   1521: double *vector(int nl, int nh)
                   1522: {
                   1523:   double *v;
                   1524:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1525:   if (!v) nrerror("allocation failure in vector");
                   1526:   return v-nl+NR_END;
                   1527: }
                   1528: 
                   1529: /************************ free vector ******************/
                   1530: void free_vector(double*v, int nl, int nh)
                   1531: {
                   1532:   free((FREE_ARG)(v+nl-NR_END));
                   1533: }
                   1534: 
                   1535: /************************ivector *******************************/
                   1536: int *ivector(long nl,long nh)
                   1537: {
                   1538:   int *v;
                   1539:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1540:   if (!v) nrerror("allocation failure in ivector");
                   1541:   return v-nl+NR_END;
                   1542: }
                   1543: 
                   1544: /******************free ivector **************************/
                   1545: void free_ivector(int *v, long nl, long nh)
                   1546: {
                   1547:   free((FREE_ARG)(v+nl-NR_END));
                   1548: }
                   1549: 
                   1550: /************************lvector *******************************/
                   1551: long *lvector(long nl,long nh)
                   1552: {
                   1553:   long *v;
                   1554:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1555:   if (!v) nrerror("allocation failure in ivector");
                   1556:   return v-nl+NR_END;
                   1557: }
                   1558: 
                   1559: /******************free lvector **************************/
                   1560: void free_lvector(long *v, long nl, long nh)
                   1561: {
                   1562:   free((FREE_ARG)(v+nl-NR_END));
                   1563: }
                   1564: 
                   1565: /******************* imatrix *******************************/
                   1566: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1567:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1568: { 
                   1569:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1570:   int **m; 
                   1571:   
                   1572:   /* allocate pointers to rows */ 
                   1573:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1574:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1575:   m += NR_END; 
                   1576:   m -= nrl; 
                   1577:   
                   1578:   
                   1579:   /* allocate rows and set pointers to them */ 
                   1580:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1581:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1582:   m[nrl] += NR_END; 
                   1583:   m[nrl] -= ncl; 
                   1584:   
                   1585:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1586:   
                   1587:   /* return pointer to array of pointers to rows */ 
                   1588:   return m; 
                   1589: } 
                   1590: 
                   1591: /****************** free_imatrix *************************/
                   1592: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1593:       int **m;
                   1594:       long nch,ncl,nrh,nrl; 
                   1595:      /* free an int matrix allocated by imatrix() */ 
                   1596: { 
                   1597:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1598:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1599: } 
                   1600: 
                   1601: /******************* matrix *******************************/
                   1602: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1603: {
                   1604:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1605:   double **m;
                   1606: 
                   1607:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1608:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1609:   m += NR_END;
                   1610:   m -= nrl;
                   1611: 
                   1612:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1613:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1614:   m[nrl] += NR_END;
                   1615:   m[nrl] -= ncl;
                   1616: 
                   1617:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1618:   return m;
1.145     brouard  1619:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1620: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1621: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1622:    */
                   1623: }
                   1624: 
                   1625: /*************************free matrix ************************/
                   1626: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1627: {
                   1628:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1629:   free((FREE_ARG)(m+nrl-NR_END));
                   1630: }
                   1631: 
                   1632: /******************* ma3x *******************************/
                   1633: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1634: {
                   1635:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1636:   double ***m;
                   1637: 
                   1638:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1639:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1640:   m += NR_END;
                   1641:   m -= nrl;
                   1642: 
                   1643:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1644:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1645:   m[nrl] += NR_END;
                   1646:   m[nrl] -= ncl;
                   1647: 
                   1648:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1649: 
                   1650:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1651:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1652:   m[nrl][ncl] += NR_END;
                   1653:   m[nrl][ncl] -= nll;
                   1654:   for (j=ncl+1; j<=nch; j++) 
                   1655:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1656:   
                   1657:   for (i=nrl+1; i<=nrh; i++) {
                   1658:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1659:     for (j=ncl+1; j<=nch; j++) 
                   1660:       m[i][j]=m[i][j-1]+nlay;
                   1661:   }
                   1662:   return m; 
                   1663:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1664:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1665:   */
                   1666: }
                   1667: 
                   1668: /*************************free ma3x ************************/
                   1669: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1670: {
                   1671:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1672:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1673:   free((FREE_ARG)(m+nrl-NR_END));
                   1674: }
                   1675: 
                   1676: /*************** function subdirf ***********/
                   1677: char *subdirf(char fileres[])
                   1678: {
                   1679:   /* Caution optionfilefiname is hidden */
                   1680:   strcpy(tmpout,optionfilefiname);
                   1681:   strcat(tmpout,"/"); /* Add to the right */
                   1682:   strcat(tmpout,fileres);
                   1683:   return tmpout;
                   1684: }
                   1685: 
                   1686: /*************** function subdirf2 ***********/
                   1687: char *subdirf2(char fileres[], char *preop)
                   1688: {
                   1689:   
                   1690:   /* Caution optionfilefiname is hidden */
                   1691:   strcpy(tmpout,optionfilefiname);
                   1692:   strcat(tmpout,"/");
                   1693:   strcat(tmpout,preop);
                   1694:   strcat(tmpout,fileres);
                   1695:   return tmpout;
                   1696: }
                   1697: 
                   1698: /*************** function subdirf3 ***********/
                   1699: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1700: {
                   1701:   
                   1702:   /* Caution optionfilefiname is hidden */
                   1703:   strcpy(tmpout,optionfilefiname);
                   1704:   strcat(tmpout,"/");
                   1705:   strcat(tmpout,preop);
                   1706:   strcat(tmpout,preop2);
                   1707:   strcat(tmpout,fileres);
                   1708:   return tmpout;
                   1709: }
1.213     brouard  1710:  
                   1711: /*************** function subdirfext ***********/
                   1712: char *subdirfext(char fileres[], char *preop, char *postop)
                   1713: {
                   1714:   
                   1715:   strcpy(tmpout,preop);
                   1716:   strcat(tmpout,fileres);
                   1717:   strcat(tmpout,postop);
                   1718:   return tmpout;
                   1719: }
1.126     brouard  1720: 
1.213     brouard  1721: /*************** function subdirfext3 ***********/
                   1722: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1723: {
                   1724:   
                   1725:   /* Caution optionfilefiname is hidden */
                   1726:   strcpy(tmpout,optionfilefiname);
                   1727:   strcat(tmpout,"/");
                   1728:   strcat(tmpout,preop);
                   1729:   strcat(tmpout,fileres);
                   1730:   strcat(tmpout,postop);
                   1731:   return tmpout;
                   1732: }
                   1733:  
1.162     brouard  1734: char *asc_diff_time(long time_sec, char ascdiff[])
                   1735: {
                   1736:   long sec_left, days, hours, minutes;
                   1737:   days = (time_sec) / (60*60*24);
                   1738:   sec_left = (time_sec) % (60*60*24);
                   1739:   hours = (sec_left) / (60*60) ;
                   1740:   sec_left = (sec_left) %(60*60);
                   1741:   minutes = (sec_left) /60;
                   1742:   sec_left = (sec_left) % (60);
                   1743:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1744:   return ascdiff;
                   1745: }
                   1746: 
1.126     brouard  1747: /***************** f1dim *************************/
                   1748: extern int ncom; 
                   1749: extern double *pcom,*xicom;
                   1750: extern double (*nrfunc)(double []); 
                   1751:  
                   1752: double f1dim(double x) 
                   1753: { 
                   1754:   int j; 
                   1755:   double f;
                   1756:   double *xt; 
                   1757:  
                   1758:   xt=vector(1,ncom); 
                   1759:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1760:   f=(*nrfunc)(xt); 
                   1761:   free_vector(xt,1,ncom); 
                   1762:   return f; 
                   1763: } 
                   1764: 
                   1765: /*****************brent *************************/
                   1766: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1767: {
                   1768:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1769:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1770:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1771:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1772:    * returned function value. 
                   1773:   */
1.126     brouard  1774:   int iter; 
                   1775:   double a,b,d,etemp;
1.159     brouard  1776:   double fu=0,fv,fw,fx;
1.164     brouard  1777:   double ftemp=0.;
1.126     brouard  1778:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1779:   double e=0.0; 
                   1780:  
                   1781:   a=(ax < cx ? ax : cx); 
                   1782:   b=(ax > cx ? ax : cx); 
                   1783:   x=w=v=bx; 
                   1784:   fw=fv=fx=(*f)(x); 
                   1785:   for (iter=1;iter<=ITMAX;iter++) { 
                   1786:     xm=0.5*(a+b); 
                   1787:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1788:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1789:     printf(".");fflush(stdout);
                   1790:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1791: #ifdef DEBUGBRENT
1.126     brouard  1792:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1793:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1794:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1795: #endif
                   1796:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1797:       *xmin=x; 
                   1798:       return fx; 
                   1799:     } 
                   1800:     ftemp=fu;
                   1801:     if (fabs(e) > tol1) { 
                   1802:       r=(x-w)*(fx-fv); 
                   1803:       q=(x-v)*(fx-fw); 
                   1804:       p=(x-v)*q-(x-w)*r; 
                   1805:       q=2.0*(q-r); 
                   1806:       if (q > 0.0) p = -p; 
                   1807:       q=fabs(q); 
                   1808:       etemp=e; 
                   1809:       e=d; 
                   1810:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1811:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1812:       else { 
1.224     brouard  1813:                                d=p/q; 
                   1814:                                u=x+d; 
                   1815:                                if (u-a < tol2 || b-u < tol2) 
                   1816:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1817:       } 
                   1818:     } else { 
                   1819:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1820:     } 
                   1821:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1822:     fu=(*f)(u); 
                   1823:     if (fu <= fx) { 
                   1824:       if (u >= x) a=x; else b=x; 
                   1825:       SHFT(v,w,x,u) 
1.183     brouard  1826:       SHFT(fv,fw,fx,fu) 
                   1827:     } else { 
                   1828:       if (u < x) a=u; else b=u; 
                   1829:       if (fu <= fw || w == x) { 
1.224     brouard  1830:                                v=w; 
                   1831:                                w=u; 
                   1832:                                fv=fw; 
                   1833:                                fw=fu; 
1.183     brouard  1834:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1835:                                v=u; 
                   1836:                                fv=fu; 
1.183     brouard  1837:       } 
                   1838:     } 
1.126     brouard  1839:   } 
                   1840:   nrerror("Too many iterations in brent"); 
                   1841:   *xmin=x; 
                   1842:   return fx; 
                   1843: } 
                   1844: 
                   1845: /****************** mnbrak ***********************/
                   1846: 
                   1847: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1848:            double (*func)(double)) 
1.183     brouard  1849: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1850: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1851: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1852: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1853:    */
1.126     brouard  1854:   double ulim,u,r,q, dum;
                   1855:   double fu; 
1.187     brouard  1856: 
                   1857:   double scale=10.;
                   1858:   int iterscale=0;
                   1859: 
                   1860:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1861:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1862: 
                   1863: 
                   1864:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1865:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1866:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1867:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1868:   /* } */
                   1869: 
1.126     brouard  1870:   if (*fb > *fa) { 
                   1871:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1872:     SHFT(dum,*fb,*fa,dum) 
                   1873:   } 
1.126     brouard  1874:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1875:   *fc=(*func)(*cx); 
1.183     brouard  1876: #ifdef DEBUG
1.224     brouard  1877:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1878:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1879: #endif
1.224     brouard  1880:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1881:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1882:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1883:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1884:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1885:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1886:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1887:       fu=(*func)(u); 
1.163     brouard  1888: #ifdef DEBUG
                   1889:       /* f(x)=A(x-u)**2+f(u) */
                   1890:       double A, fparabu; 
                   1891:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1892:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1893:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1894:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1895:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1896:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1897:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1898:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1899: #endif 
1.184     brouard  1900: #ifdef MNBRAKORIGINAL
1.183     brouard  1901: #else
1.191     brouard  1902: /*       if (fu > *fc) { */
                   1903: /* #ifdef DEBUG */
                   1904: /*       printf("mnbrak4  fu > fc \n"); */
                   1905: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1906: /* #endif */
                   1907: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1908: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1909: /*     dum=u; /\* Shifting c and u *\/ */
                   1910: /*     u = *cx; */
                   1911: /*     *cx = dum; */
                   1912: /*     dum = fu; */
                   1913: /*     fu = *fc; */
                   1914: /*     *fc =dum; */
                   1915: /*       } else { /\* end *\/ */
                   1916: /* #ifdef DEBUG */
                   1917: /*       printf("mnbrak3  fu < fc \n"); */
                   1918: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1919: /* #endif */
                   1920: /*     dum=u; /\* Shifting c and u *\/ */
                   1921: /*     u = *cx; */
                   1922: /*     *cx = dum; */
                   1923: /*     dum = fu; */
                   1924: /*     fu = *fc; */
                   1925: /*     *fc =dum; */
                   1926: /*       } */
1.224     brouard  1927: #ifdef DEBUGMNBRAK
                   1928:                 double A, fparabu; 
                   1929:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1930:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1931:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1932:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1933: #endif
1.191     brouard  1934:       dum=u; /* Shifting c and u */
                   1935:       u = *cx;
                   1936:       *cx = dum;
                   1937:       dum = fu;
                   1938:       fu = *fc;
                   1939:       *fc =dum;
1.183     brouard  1940: #endif
1.162     brouard  1941:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1942: #ifdef DEBUG
1.224     brouard  1943:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1944:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1945: #endif
1.126     brouard  1946:       fu=(*func)(u); 
                   1947:       if (fu < *fc) { 
1.183     brouard  1948: #ifdef DEBUG
1.224     brouard  1949:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1950:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1951: #endif
                   1952:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1953:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1954: #ifdef DEBUG
                   1955:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1956: #endif
                   1957:       } 
1.162     brouard  1958:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1959: #ifdef DEBUG
1.224     brouard  1960:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1961:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1962: #endif
1.126     brouard  1963:       u=ulim; 
                   1964:       fu=(*func)(u); 
1.183     brouard  1965:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1966: #ifdef DEBUG
1.224     brouard  1967:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1968:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1969: #endif
1.126     brouard  1970:       u=(*cx)+GOLD*(*cx-*bx); 
                   1971:       fu=(*func)(u); 
1.224     brouard  1972: #ifdef DEBUG
                   1973:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1974:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1975: #endif
1.183     brouard  1976:     } /* end tests */
1.126     brouard  1977:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1978:     SHFT(*fa,*fb,*fc,fu) 
                   1979: #ifdef DEBUG
1.224     brouard  1980:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1981:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  1982: #endif
                   1983:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  1984: } 
                   1985: 
                   1986: /*************** linmin ************************/
1.162     brouard  1987: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   1988: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   1989: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   1990: the value of func at the returned location p . This is actually all accomplished by calling the
                   1991: routines mnbrak and brent .*/
1.126     brouard  1992: int ncom; 
                   1993: double *pcom,*xicom;
                   1994: double (*nrfunc)(double []); 
                   1995:  
1.224     brouard  1996: #ifdef LINMINORIGINAL
1.126     brouard  1997: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  1998: #else
                   1999: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2000: #endif
1.126     brouard  2001: { 
                   2002:   double brent(double ax, double bx, double cx, 
                   2003:               double (*f)(double), double tol, double *xmin); 
                   2004:   double f1dim(double x); 
                   2005:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2006:              double *fc, double (*func)(double)); 
                   2007:   int j; 
                   2008:   double xx,xmin,bx,ax; 
                   2009:   double fx,fb,fa;
1.187     brouard  2010: 
1.203     brouard  2011: #ifdef LINMINORIGINAL
                   2012: #else
                   2013:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2014: #endif
                   2015:   
1.126     brouard  2016:   ncom=n; 
                   2017:   pcom=vector(1,n); 
                   2018:   xicom=vector(1,n); 
                   2019:   nrfunc=func; 
                   2020:   for (j=1;j<=n;j++) { 
                   2021:     pcom[j]=p[j]; 
1.202     brouard  2022:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2023:   } 
1.187     brouard  2024: 
1.203     brouard  2025: #ifdef LINMINORIGINAL
                   2026:   xx=1.;
                   2027: #else
                   2028:   axs=0.0;
                   2029:   xxs=1.;
                   2030:   do{
                   2031:     xx= xxs;
                   2032: #endif
1.187     brouard  2033:     ax=0.;
                   2034:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2035:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2036:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2037:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2038:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2039:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2040:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2041: #ifdef LINMINORIGINAL
                   2042: #else
                   2043:     if (fx != fx){
1.224     brouard  2044:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2045:                        printf("|");
                   2046:                        fprintf(ficlog,"|");
1.203     brouard  2047: #ifdef DEBUGLINMIN
1.224     brouard  2048:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2049: #endif
                   2050:     }
1.224     brouard  2051:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2052: #endif
                   2053:   
1.191     brouard  2054: #ifdef DEBUGLINMIN
                   2055:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2056:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2057: #endif
1.224     brouard  2058: #ifdef LINMINORIGINAL
                   2059: #else
                   2060:        if(fb == fx){ /* Flat function in the direction */
                   2061:                xmin=xx;
                   2062:     *flat=1;
                   2063:        }else{
                   2064:     *flat=0;
                   2065: #endif
                   2066:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2067:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2068:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2069:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2070:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2071:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2072: #ifdef DEBUG
1.224     brouard  2073:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2074:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2075: #endif
                   2076: #ifdef LINMINORIGINAL
                   2077: #else
                   2078:                        }
1.126     brouard  2079: #endif
1.191     brouard  2080: #ifdef DEBUGLINMIN
                   2081:   printf("linmin end ");
1.202     brouard  2082:   fprintf(ficlog,"linmin end ");
1.191     brouard  2083: #endif
1.126     brouard  2084:   for (j=1;j<=n;j++) { 
1.203     brouard  2085: #ifdef LINMINORIGINAL
                   2086:     xi[j] *= xmin; 
                   2087: #else
                   2088: #ifdef DEBUGLINMIN
                   2089:     if(xxs <1.0)
                   2090:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2091: #endif
                   2092:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2093: #ifdef DEBUGLINMIN
                   2094:     if(xxs <1.0)
                   2095:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2096: #endif
                   2097: #endif
1.187     brouard  2098:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2099:   } 
1.191     brouard  2100: #ifdef DEBUGLINMIN
1.203     brouard  2101:   printf("\n");
1.191     brouard  2102:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2103:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2104:   for (j=1;j<=n;j++) { 
1.202     brouard  2105:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2106:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2107:     if(j % ncovmodel == 0){
1.191     brouard  2108:       printf("\n");
1.202     brouard  2109:       fprintf(ficlog,"\n");
                   2110:     }
1.191     brouard  2111:   }
1.203     brouard  2112: #else
1.191     brouard  2113: #endif
1.126     brouard  2114:   free_vector(xicom,1,n); 
                   2115:   free_vector(pcom,1,n); 
                   2116: } 
                   2117: 
                   2118: 
                   2119: /*************** powell ************************/
1.162     brouard  2120: /*
                   2121: Minimization of a function func of n variables. Input consists of an initial starting point
                   2122: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2123: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2124: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2125: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2126: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2127:  */
1.224     brouard  2128: #ifdef LINMINORIGINAL
                   2129: #else
                   2130:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2131:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2132: #endif
1.126     brouard  2133: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2134:            double (*func)(double [])) 
                   2135: { 
1.224     brouard  2136: #ifdef LINMINORIGINAL
                   2137:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2138:              double (*func)(double [])); 
1.224     brouard  2139: #else 
1.241     brouard  2140:  void linmin(double p[], double xi[], int n, double *fret,
                   2141:             double (*func)(double []),int *flat); 
1.224     brouard  2142: #endif
1.239     brouard  2143:  int i,ibig,j,jk,k; 
1.126     brouard  2144:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2145:   double directest;
1.126     brouard  2146:   double fp,fptt;
                   2147:   double *xits;
                   2148:   int niterf, itmp;
1.224     brouard  2149: #ifdef LINMINORIGINAL
                   2150: #else
                   2151: 
                   2152:   flatdir=ivector(1,n); 
                   2153:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2154: #endif
1.126     brouard  2155: 
                   2156:   pt=vector(1,n); 
                   2157:   ptt=vector(1,n); 
                   2158:   xit=vector(1,n); 
                   2159:   xits=vector(1,n); 
                   2160:   *fret=(*func)(p); 
                   2161:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2162:   rcurr_time = time(NULL);  
1.126     brouard  2163:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2164:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2165:     ibig=0; 
                   2166:     del=0.0; 
1.157     brouard  2167:     rlast_time=rcurr_time;
                   2168:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2169:     rcurr_time = time(NULL);  
                   2170:     curr_time = *localtime(&rcurr_time);
                   2171:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2172:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2173: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2174:     for (i=1;i<=n;i++) {
1.126     brouard  2175:       fprintf(ficrespow," %.12lf", p[i]);
                   2176:     }
1.239     brouard  2177:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2178:     printf("\n#model=  1      +     age ");
                   2179:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2180:     if(nagesqr==1){
1.241     brouard  2181:        printf("  + age*age  ");
                   2182:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2183:     }
                   2184:     for(j=1;j <=ncovmodel-2;j++){
                   2185:       if(Typevar[j]==0) {
                   2186:        printf("  +      V%d  ",Tvar[j]);
                   2187:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2188:       }else if(Typevar[j]==1) {
                   2189:        printf("  +    V%d*age ",Tvar[j]);
                   2190:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2191:       }else if(Typevar[j]==2) {
                   2192:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2193:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2194:       }
                   2195:     }
1.126     brouard  2196:     printf("\n");
1.239     brouard  2197: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2198: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2199:     fprintf(ficlog,"\n");
1.239     brouard  2200:     for(i=1,jk=1; i <=nlstate; i++){
                   2201:       for(k=1; k <=(nlstate+ndeath); k++){
                   2202:        if (k != i) {
                   2203:          printf("%d%d ",i,k);
                   2204:          fprintf(ficlog,"%d%d ",i,k);
                   2205:          for(j=1; j <=ncovmodel; j++){
                   2206:            printf("%12.7f ",p[jk]);
                   2207:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2208:            jk++; 
                   2209:          }
                   2210:          printf("\n");
                   2211:          fprintf(ficlog,"\n");
                   2212:        }
                   2213:       }
                   2214:     }
1.241     brouard  2215:     if(*iter <=3 && *iter >1){
1.157     brouard  2216:       tml = *localtime(&rcurr_time);
                   2217:       strcpy(strcurr,asctime(&tml));
                   2218:       rforecast_time=rcurr_time; 
1.126     brouard  2219:       itmp = strlen(strcurr);
                   2220:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2221:        strcurr[itmp-1]='\0';
1.162     brouard  2222:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2223:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2224:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2225:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2226:        forecast_time = *localtime(&rforecast_time);
                   2227:        strcpy(strfor,asctime(&forecast_time));
                   2228:        itmp = strlen(strfor);
                   2229:        if(strfor[itmp-1]=='\n')
                   2230:          strfor[itmp-1]='\0';
                   2231:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2232:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2233:       }
                   2234:     }
1.187     brouard  2235:     for (i=1;i<=n;i++) { /* For each direction i */
                   2236:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2237:       fptt=(*fret); 
                   2238: #ifdef DEBUG
1.203     brouard  2239:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2240:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2241: #endif
1.203     brouard  2242:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2243:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2244: #ifdef LINMINORIGINAL
1.188     brouard  2245:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2246: #else
                   2247:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2248:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2249: #endif
                   2250:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2251:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2252:                                /* because that direction will be replaced unless the gain del is small */
                   2253:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2254:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2255:                                /* with the new direction. */
                   2256:                                del=fabs(fptt-(*fret)); 
                   2257:                                ibig=i; 
1.126     brouard  2258:       } 
                   2259: #ifdef DEBUG
                   2260:       printf("%d %.12e",i,(*fret));
                   2261:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2262:       for (j=1;j<=n;j++) {
1.224     brouard  2263:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2264:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2265:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2266:       }
                   2267:       for(j=1;j<=n;j++) {
1.225     brouard  2268:                                printf(" p(%d)=%.12e",j,p[j]);
                   2269:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2270:       }
                   2271:       printf("\n");
                   2272:       fprintf(ficlog,"\n");
                   2273: #endif
1.187     brouard  2274:     } /* end loop on each direction i */
                   2275:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2276:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2277:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2278:       for(j=1;j<=n;j++) {
1.225     brouard  2279:                                if(flatdir[j] >0){
                   2280:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2281:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2282:                                }
                   2283:                                /* printf("\n"); */
                   2284:                                /* fprintf(ficlog,"\n"); */
                   2285:                        }
1.243     brouard  2286:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2287:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2288:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2289:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2290:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2291:       /* decreased of more than 3.84  */
                   2292:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2293:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2294:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2295:                        
1.188     brouard  2296:       /* Starting the program with initial values given by a former maximization will simply change */
                   2297:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2298:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2299:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2300: #ifdef DEBUG
                   2301:       int k[2],l;
                   2302:       k[0]=1;
                   2303:       k[1]=-1;
                   2304:       printf("Max: %.12e",(*func)(p));
                   2305:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2306:       for (j=1;j<=n;j++) {
                   2307:        printf(" %.12e",p[j]);
                   2308:        fprintf(ficlog," %.12e",p[j]);
                   2309:       }
                   2310:       printf("\n");
                   2311:       fprintf(ficlog,"\n");
                   2312:       for(l=0;l<=1;l++) {
                   2313:        for (j=1;j<=n;j++) {
                   2314:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2315:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2316:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2317:        }
                   2318:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2319:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2320:       }
                   2321: #endif
                   2322: 
1.224     brouard  2323: #ifdef LINMINORIGINAL
                   2324: #else
                   2325:       free_ivector(flatdir,1,n); 
                   2326: #endif
1.126     brouard  2327:       free_vector(xit,1,n); 
                   2328:       free_vector(xits,1,n); 
                   2329:       free_vector(ptt,1,n); 
                   2330:       free_vector(pt,1,n); 
                   2331:       return; 
1.192     brouard  2332:     } /* enough precision */ 
1.240     brouard  2333:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2334:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2335:       ptt[j]=2.0*p[j]-pt[j]; 
                   2336:       xit[j]=p[j]-pt[j]; 
                   2337:       pt[j]=p[j]; 
                   2338:     } 
1.181     brouard  2339:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2340: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2341:                if (*iter <=4) {
1.225     brouard  2342: #else
                   2343: #endif
1.224     brouard  2344: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2345: #else
1.161     brouard  2346:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2347: #endif
1.162     brouard  2348:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2349:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2350:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2351:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2352:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2353:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2354:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2355:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2356:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2357:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2358:       /* mu² and del² are equal when f3=f1 */
                   2359:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2360:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2361:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2362:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2363: #ifdef NRCORIGINAL
                   2364:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2365: #else
                   2366:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2367:       t= t- del*SQR(fp-fptt);
1.183     brouard  2368: #endif
1.202     brouard  2369:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2370: #ifdef DEBUG
1.181     brouard  2371:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2372:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2373:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2374:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2375:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2376:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2377:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2378:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2379: #endif
1.183     brouard  2380: #ifdef POWELLORIGINAL
                   2381:       if (t < 0.0) { /* Then we use it for new direction */
                   2382: #else
1.182     brouard  2383:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2384:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2385:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2386:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2387:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2388:       } 
1.181     brouard  2389:       if (directest < 0.0) { /* Then we use it for new direction */
                   2390: #endif
1.191     brouard  2391: #ifdef DEBUGLINMIN
1.234     brouard  2392:        printf("Before linmin in direction P%d-P0\n",n);
                   2393:        for (j=1;j<=n;j++) {
                   2394:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2395:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2396:          if(j % ncovmodel == 0){
                   2397:            printf("\n");
                   2398:            fprintf(ficlog,"\n");
                   2399:          }
                   2400:        }
1.224     brouard  2401: #endif
                   2402: #ifdef LINMINORIGINAL
1.234     brouard  2403:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2404: #else
1.234     brouard  2405:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2406:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2407: #endif
1.234     brouard  2408:        
1.191     brouard  2409: #ifdef DEBUGLINMIN
1.234     brouard  2410:        for (j=1;j<=n;j++) { 
                   2411:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2412:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2413:          if(j % ncovmodel == 0){
                   2414:            printf("\n");
                   2415:            fprintf(ficlog,"\n");
                   2416:          }
                   2417:        }
1.224     brouard  2418: #endif
1.234     brouard  2419:        for (j=1;j<=n;j++) { 
                   2420:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2421:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2422:        }
1.224     brouard  2423: #ifdef LINMINORIGINAL
                   2424: #else
1.234     brouard  2425:        for (j=1, flatd=0;j<=n;j++) {
                   2426:          if(flatdir[j]>0)
                   2427:            flatd++;
                   2428:        }
                   2429:        if(flatd >0){
1.255     brouard  2430:          printf("%d flat directions: ",flatd);
                   2431:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2432:          for (j=1;j<=n;j++) { 
                   2433:            if(flatdir[j]>0){
                   2434:              printf("%d ",j);
                   2435:              fprintf(ficlog,"%d ",j);
                   2436:            }
                   2437:          }
                   2438:          printf("\n");
                   2439:          fprintf(ficlog,"\n");
                   2440:        }
1.191     brouard  2441: #endif
1.234     brouard  2442:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2443:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2444:        
1.126     brouard  2445: #ifdef DEBUG
1.234     brouard  2446:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2447:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2448:        for(j=1;j<=n;j++){
                   2449:          printf(" %lf",xit[j]);
                   2450:          fprintf(ficlog," %lf",xit[j]);
                   2451:        }
                   2452:        printf("\n");
                   2453:        fprintf(ficlog,"\n");
1.126     brouard  2454: #endif
1.192     brouard  2455:       } /* end of t or directest negative */
1.224     brouard  2456: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2457: #else
1.234     brouard  2458:       } /* end if (fptt < fp)  */
1.192     brouard  2459: #endif
1.225     brouard  2460: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2461:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2462: #else
1.224     brouard  2463: #endif
1.234     brouard  2464:                } /* loop iteration */ 
1.126     brouard  2465: } 
1.234     brouard  2466:   
1.126     brouard  2467: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2468:   
1.235     brouard  2469:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2470:   {
1.235     brouard  2471:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2472:        (and selected quantitative values in nres)
                   2473:        by left multiplying the unit
1.234     brouard  2474:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2475:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2476:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2477:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2478:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2479:   /* Initial matrix pimij */
                   2480:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2481:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2482:   /*  0,                   0                  , 1} */
                   2483:   /*
                   2484:    * and after some iteration: */
                   2485:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2486:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2487:   /*  0,                   0                  , 1} */
                   2488:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2489:   /* {0.51571254859325999, 0.4842874514067399, */
                   2490:   /*  0.51326036147820708, 0.48673963852179264} */
                   2491:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2492:     
1.126     brouard  2493:   int i, ii,j,k;
1.209     brouard  2494:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2495:   /* double **matprod2(); */ /* test */
1.218     brouard  2496:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2497:   double **newm;
1.209     brouard  2498:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2499:   int ncvloop=0;
1.169     brouard  2500:   
1.209     brouard  2501:   min=vector(1,nlstate);
                   2502:   max=vector(1,nlstate);
                   2503:   meandiff=vector(1,nlstate);
                   2504: 
1.218     brouard  2505:        /* Starting with matrix unity */
1.126     brouard  2506:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2507:     for (j=1;j<=nlstate+ndeath;j++){
                   2508:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2509:     }
1.169     brouard  2510:   
                   2511:   cov[1]=1.;
                   2512:   
                   2513:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2514:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2515:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2516:     ncvloop++;
1.126     brouard  2517:     newm=savm;
                   2518:     /* Covariates have to be included here again */
1.138     brouard  2519:     cov[2]=agefin;
1.187     brouard  2520:     if(nagesqr==1)
                   2521:       cov[3]= agefin*agefin;;
1.234     brouard  2522:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2523:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2524:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2525:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2526:     }
                   2527:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2528:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2529:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2530:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2531:     }
1.237     brouard  2532:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2533:       if(Dummy[Tvar[Tage[k]]]){
                   2534:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2535:       } else{
1.235     brouard  2536:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2537:       }
1.235     brouard  2538:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2539:     }
1.237     brouard  2540:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2541:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2542:       if(Dummy[Tvard[k][1]==0]){
                   2543:        if(Dummy[Tvard[k][2]==0]){
                   2544:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2545:        }else{
                   2546:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2547:        }
                   2548:       }else{
                   2549:        if(Dummy[Tvard[k][2]==0]){
                   2550:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2551:        }else{
                   2552:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2553:        }
                   2554:       }
1.234     brouard  2555:     }
1.138     brouard  2556:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2557:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2558:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2559:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2560:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2561:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2562:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2563:     
1.126     brouard  2564:     savm=oldm;
                   2565:     oldm=newm;
1.209     brouard  2566: 
                   2567:     for(j=1; j<=nlstate; j++){
                   2568:       max[j]=0.;
                   2569:       min[j]=1.;
                   2570:     }
                   2571:     for(i=1;i<=nlstate;i++){
                   2572:       sumnew=0;
                   2573:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2574:       for(j=1; j<=nlstate; j++){ 
                   2575:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2576:        max[j]=FMAX(max[j],prlim[i][j]);
                   2577:        min[j]=FMIN(min[j],prlim[i][j]);
                   2578:       }
                   2579:     }
                   2580: 
1.126     brouard  2581:     maxmax=0.;
1.209     brouard  2582:     for(j=1; j<=nlstate; j++){
                   2583:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2584:       maxmax=FMAX(maxmax,meandiff[j]);
                   2585:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2586:     } /* j loop */
1.203     brouard  2587:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2588:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2589:     if(maxmax < ftolpl){
1.209     brouard  2590:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2591:       free_vector(min,1,nlstate);
                   2592:       free_vector(max,1,nlstate);
                   2593:       free_vector(meandiff,1,nlstate);
1.126     brouard  2594:       return prlim;
                   2595:     }
1.169     brouard  2596:   } /* age loop */
1.208     brouard  2597:     /* After some age loop it doesn't converge */
1.209     brouard  2598:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2599: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2600:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2601:   free_vector(min,1,nlstate);
                   2602:   free_vector(max,1,nlstate);
                   2603:   free_vector(meandiff,1,nlstate);
1.208     brouard  2604:   
1.169     brouard  2605:   return prlim; /* should not reach here */
1.126     brouard  2606: }
                   2607: 
1.217     brouard  2608: 
                   2609:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2610: 
1.218     brouard  2611:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2612:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2613:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2614: {
1.218     brouard  2615:   /* Computes the prevalence limit in each live state at age x and covariate ij by left multiplying the unit
1.217     brouard  2616:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2617:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2618:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2619:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2620:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2621:   /* Initial matrix pimij */
                   2622:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2623:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2624:   /*  0,                   0                  , 1} */
                   2625:   /*
                   2626:    * and after some iteration: */
                   2627:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2628:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2629:   /*  0,                   0                  , 1} */
                   2630:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2631:   /* {0.51571254859325999, 0.4842874514067399, */
                   2632:   /*  0.51326036147820708, 0.48673963852179264} */
                   2633:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2634: 
                   2635:   int i, ii,j,k;
1.247     brouard  2636:   int first=0;
1.217     brouard  2637:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2638:   /* double **matprod2(); */ /* test */
                   2639:   double **out, cov[NCOVMAX+1], **bmij();
                   2640:   double **newm;
1.218     brouard  2641:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2642:   double        **oldm, **savm;  /* for use */
                   2643: 
1.217     brouard  2644:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2645:   int ncvloop=0;
                   2646:   
                   2647:   min=vector(1,nlstate);
                   2648:   max=vector(1,nlstate);
                   2649:   meandiff=vector(1,nlstate);
                   2650: 
1.218     brouard  2651:        dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2652:        oldm=oldms; savm=savms;
                   2653: 
                   2654:        /* Starting with matrix unity */
                   2655:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   2656:                for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2657:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2658:     }
                   2659:   
                   2660:   cov[1]=1.;
                   2661:   
                   2662:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2663:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2664:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2665:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2666:     ncvloop++;
1.218     brouard  2667:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2668:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2669:     /* Covariates have to be included here again */
                   2670:     cov[2]=agefin;
                   2671:     if(nagesqr==1)
                   2672:       cov[3]= agefin*agefin;;
1.242     brouard  2673:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2674:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2675:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   2676:       /* printf("bprevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   2677:     }
                   2678:     /* for (k=1; k<=cptcovn;k++) { */
                   2679:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2680:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2681:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2682:     /* } */
                   2683:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2684:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2685:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2686:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2687:     }
                   2688:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2689:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2690:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2691:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2692:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2693:       if(Dummy[Tvar[Tage[k]]]){
                   2694:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2695:       } else{
                   2696:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2697:       }
                   2698:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2699:     }
                   2700:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2701:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2702:       if(Dummy[Tvard[k][1]==0]){
                   2703:        if(Dummy[Tvard[k][2]==0]){
                   2704:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2705:        }else{
                   2706:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2707:        }
                   2708:       }else{
                   2709:        if(Dummy[Tvard[k][2]==0]){
                   2710:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2711:        }else{
                   2712:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2713:        }
                   2714:       }
1.217     brouard  2715:     }
                   2716:     
                   2717:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2718:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2719:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2720:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2721:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2722:                /* ij should be linked to the correct index of cov */
                   2723:                /* age and covariate values ij are in 'cov', but we need to pass
                   2724:                 * ij for the observed prevalence at age and status and covariate
                   2725:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2726:                 */
                   2727:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2728:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2729:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.217     brouard  2730:     savm=oldm;
                   2731:     oldm=newm;
                   2732:     for(j=1; j<=nlstate; j++){
                   2733:       max[j]=0.;
                   2734:       min[j]=1.;
                   2735:     }
                   2736:     for(j=1; j<=nlstate; j++){ 
                   2737:       for(i=1;i<=nlstate;i++){
1.234     brouard  2738:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2739:        bprlim[i][j]= newm[i][j];
                   2740:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2741:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2742:       }
                   2743:     }
1.218     brouard  2744:                
1.217     brouard  2745:     maxmax=0.;
                   2746:     for(i=1; i<=nlstate; i++){
                   2747:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2748:       maxmax=FMAX(maxmax,meandiff[i]);
                   2749:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
                   2750:     } /* j loop */
                   2751:     *ncvyear= -( (int)age- (int)agefin);
1.218     brouard  2752:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear);*/
1.217     brouard  2753:     if(maxmax < ftolpl){
1.220     brouard  2754:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2755:       free_vector(min,1,nlstate);
                   2756:       free_vector(max,1,nlstate);
                   2757:       free_vector(meandiff,1,nlstate);
                   2758:       return bprlim;
                   2759:     }
                   2760:   } /* age loop */
                   2761:     /* After some age loop it doesn't converge */
1.247     brouard  2762:   if(first){
                   2763:     first=1;
                   2764:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2765: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2766:   }
                   2767:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2768: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2769:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2770:   free_vector(min,1,nlstate);
                   2771:   free_vector(max,1,nlstate);
                   2772:   free_vector(meandiff,1,nlstate);
                   2773:   
                   2774:   return bprlim; /* should not reach here */
                   2775: }
                   2776: 
1.126     brouard  2777: /*************** transition probabilities ***************/ 
                   2778: 
                   2779: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2780: {
1.138     brouard  2781:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2782:      computes the probability to be observed in state j being in state i by appying the
                   2783:      model to the ncovmodel covariates (including constant and age).
                   2784:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2785:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2786:      ncth covariate in the global vector x is given by the formula:
                   2787:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2788:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2789:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2790:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2791:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2792:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2793:   */
                   2794:   double s1, lnpijopii;
1.126     brouard  2795:   /*double t34;*/
1.164     brouard  2796:   int i,j, nc, ii, jj;
1.126     brouard  2797: 
1.223     brouard  2798:   for(i=1; i<= nlstate; i++){
                   2799:     for(j=1; j<i;j++){
                   2800:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2801:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2802:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2803:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2804:       }
                   2805:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2806:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2807:     }
                   2808:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2809:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2810:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2811:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2812:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2813:       }
                   2814:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2815:     }
                   2816:   }
1.218     brouard  2817:   
1.223     brouard  2818:   for(i=1; i<= nlstate; i++){
                   2819:     s1=0;
                   2820:     for(j=1; j<i; j++){
                   2821:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2822:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2823:     }
                   2824:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2825:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2826:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2827:     }
                   2828:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2829:     ps[i][i]=1./(s1+1.);
                   2830:     /* Computing other pijs */
                   2831:     for(j=1; j<i; j++)
                   2832:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2833:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2834:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2835:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2836:   } /* end i */
1.218     brouard  2837:   
1.223     brouard  2838:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2839:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2840:       ps[ii][jj]=0;
                   2841:       ps[ii][ii]=1;
                   2842:     }
                   2843:   }
1.218     brouard  2844:   
                   2845:   
1.223     brouard  2846:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2847:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2848:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2849:   /*   } */
                   2850:   /*   printf("\n "); */
                   2851:   /* } */
                   2852:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2853:   /*
                   2854:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2855:                goto end;*/
1.223     brouard  2856:   return ps;
1.126     brouard  2857: }
                   2858: 
1.218     brouard  2859: /*************** backward transition probabilities ***************/ 
                   2860: 
                   2861:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2862: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2863:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2864: {
1.222     brouard  2865:   /* Computes the backward probability at age agefin and covariate ij
                   2866:    * and returns in **ps as well as **bmij.
                   2867:    */
1.218     brouard  2868:   int i, ii, j,k;
1.222     brouard  2869:   
                   2870:   double **out, **pmij();
                   2871:   double sumnew=0.;
1.218     brouard  2872:   double agefin;
1.222     brouard  2873:   
                   2874:   double **dnewm, **dsavm, **doldm;
                   2875:   double **bbmij;
                   2876:   
1.218     brouard  2877:   doldm=ddoldms; /* global pointers */
1.222     brouard  2878:   dnewm=ddnewms;
                   2879:   dsavm=ddsavms;
                   2880:   
                   2881:   agefin=cov[2];
                   2882:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
                   2883:      the observed prevalence (with this covariate ij) */
                   2884:   dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate);
                   2885:   /* We do have the matrix Px in savm  and we need pij */
                   2886:   for (j=1;j<=nlstate+ndeath;j++){
                   2887:     sumnew=0.; /* w1 p11 + w2 p21 only on live states */
                   2888:     for (ii=1;ii<=nlstate;ii++){
                   2889:       sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij];
                   2890:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
                   2891:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2892:       if(sumnew >= 1.e-10){
                   2893:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
                   2894:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2895:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
                   2896:        /*      doldm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
                   2897:        /* }else */
                   2898:        doldm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2899:       }else{
1.242     brouard  2900:        ;
                   2901:        /* printf("ii=%d, i=%d, doldm=%lf dsavm=%lf, probs=%lf, sumnew=%lf,agefin=%d\n",ii,j,doldm[ii][j],dsavm[ii][j],prevacurrent[(int)agefin][ii][ij],sumnew, (int)agefin); */
1.222     brouard  2902:       }
                   2903:     } /*End ii */
                   2904:   } /* End j, At the end doldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2905:   /* left Product of this diag matrix by dsavm=Px (newm=dsavm*doldm) */
                   2906:   bbmij=matprod2(dnewm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, doldm); /* Bug Valgrind */
                   2907:   /* dsavm=doldm; /\* dsavm is now diag [1/(w_1p1i+w_2 p2i)] but can be overwritten*\/ */
                   2908:   /* doldm=dnewm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2909:   /* dnewm=dsavm; /\* doldm is now Px * diag [1/(w_1p1i+w_2 p2i)] *\/ */
                   2910:   /* left Product of this matrix by diag matrix of prevalences (savm) */
                   2911:   for (j=1;j<=nlstate+ndeath;j++){
                   2912:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2913:       dsavm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij] : 0.0);
                   2914:     }
                   2915:   } /* End j, At the end oldm is diag[1/(w_1p1i+w_2 p2i)] */
                   2916:   ps=matprod2(doldm, dsavm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dnewm); /* Bug Valgrind */
                   2917:   /* newm or out is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
                   2918:   /* end bmij */
                   2919:   return ps; 
1.218     brouard  2920: }
1.217     brouard  2921: /*************** transition probabilities ***************/ 
                   2922: 
1.218     brouard  2923: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2924: {
                   2925:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2926:      computes the probability to be observed in state j being in state i by appying the
                   2927:      model to the ncovmodel covariates (including constant and age).
                   2928:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2929:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2930:      ncth covariate in the global vector x is given by the formula:
                   2931:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2932:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2933:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2934:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2935:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2936:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2937:   */
                   2938:   double s1, lnpijopii;
                   2939:   /*double t34;*/
                   2940:   int i,j, nc, ii, jj;
                   2941: 
1.234     brouard  2942:   for(i=1; i<= nlstate; i++){
                   2943:     for(j=1; j<i;j++){
                   2944:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2945:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2946:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2947:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2948:       }
                   2949:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2950:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2951:     }
                   2952:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2953:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2954:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2955:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2956:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2957:       }
                   2958:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2959:     }
                   2960:   }
                   2961:   
                   2962:   for(i=1; i<= nlstate; i++){
                   2963:     s1=0;
                   2964:     for(j=1; j<i; j++){
                   2965:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2966:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2967:     }
                   2968:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2969:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2970:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2971:     }
                   2972:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2973:     ps[i][i]=1./(s1+1.);
                   2974:     /* Computing other pijs */
                   2975:     for(j=1; j<i; j++)
                   2976:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2977:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2978:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2979:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2980:   } /* end i */
                   2981:   
                   2982:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2983:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2984:       ps[ii][jj]=0;
                   2985:       ps[ii][ii]=1;
                   2986:     }
                   2987:   }
                   2988:   /* Added for backcast */ /* Transposed matrix too */
                   2989:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   2990:     s1=0.;
                   2991:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   2992:       s1+=ps[ii][jj];
                   2993:     }
                   2994:     for(ii=1; ii<= nlstate; ii++){
                   2995:       ps[ii][jj]=ps[ii][jj]/s1;
                   2996:     }
                   2997:   }
                   2998:   /* Transposition */
                   2999:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3000:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3001:       s1=ps[ii][jj];
                   3002:       ps[ii][jj]=ps[jj][ii];
                   3003:       ps[jj][ii]=s1;
                   3004:     }
                   3005:   }
                   3006:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3007:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3008:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3009:   /*   } */
                   3010:   /*   printf("\n "); */
                   3011:   /* } */
                   3012:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3013:   /*
                   3014:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3015:     goto end;*/
                   3016:   return ps;
1.217     brouard  3017: }
                   3018: 
                   3019: 
1.126     brouard  3020: /**************** Product of 2 matrices ******************/
                   3021: 
1.145     brouard  3022: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3023: {
                   3024:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3025:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3026:   /* in, b, out are matrice of pointers which should have been initialized 
                   3027:      before: only the contents of out is modified. The function returns
                   3028:      a pointer to pointers identical to out */
1.145     brouard  3029:   int i, j, k;
1.126     brouard  3030:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3031:     for(k=ncolol; k<=ncoloh; k++){
                   3032:       out[i][k]=0.;
                   3033:       for(j=ncl; j<=nch; j++)
                   3034:        out[i][k] +=in[i][j]*b[j][k];
                   3035:     }
1.126     brouard  3036:   return out;
                   3037: }
                   3038: 
                   3039: 
                   3040: /************* Higher Matrix Product ***************/
                   3041: 
1.235     brouard  3042: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3043: {
1.218     brouard  3044:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3045:      'nhstepm*hstepm*stepm' months (i.e. until
                   3046:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3047:      nhstepm*hstepm matrices. 
                   3048:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3049:      (typically every 2 years instead of every month which is too big 
                   3050:      for the memory).
                   3051:      Model is determined by parameters x and covariates have to be 
                   3052:      included manually here. 
                   3053: 
                   3054:      */
                   3055: 
                   3056:   int i, j, d, h, k;
1.131     brouard  3057:   double **out, cov[NCOVMAX+1];
1.126     brouard  3058:   double **newm;
1.187     brouard  3059:   double agexact;
1.214     brouard  3060:   double agebegin, ageend;
1.126     brouard  3061: 
                   3062:   /* Hstepm could be zero and should return the unit matrix */
                   3063:   for (i=1;i<=nlstate+ndeath;i++)
                   3064:     for (j=1;j<=nlstate+ndeath;j++){
                   3065:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3066:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3067:     }
                   3068:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3069:   for(h=1; h <=nhstepm; h++){
                   3070:     for(d=1; d <=hstepm; d++){
                   3071:       newm=savm;
                   3072:       /* Covariates have to be included here again */
                   3073:       cov[1]=1.;
1.214     brouard  3074:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3075:       cov[2]=agexact;
                   3076:       if(nagesqr==1)
1.227     brouard  3077:        cov[3]= agexact*agexact;
1.235     brouard  3078:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3079:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3080:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3081:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3082:       }
                   3083:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3084:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3085:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3086:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3087:       }
                   3088:       for (k=1; k<=cptcovage;k++){
                   3089:        if(Dummy[Tvar[Tage[k]]]){
                   3090:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3091:        } else{
                   3092:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3093:        }
                   3094:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3095:       }
                   3096:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3097:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3098:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3099:       }
                   3100:       /* for (k=1; k<=cptcovn;k++)  */
                   3101:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3102:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3103:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3104:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3105:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3106:       
                   3107:       
1.126     brouard  3108:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3109:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3110:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3111:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3112:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3113:       /* if((int)age == 70){ */
                   3114:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3115:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3116:       /*         printf("%d pmmij ",i); */
                   3117:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3118:       /*           printf("%f ",pmmij[i][j]); */
                   3119:       /*         } */
                   3120:       /*         printf(" oldm "); */
                   3121:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3122:       /*           printf("%f ",oldm[i][j]); */
                   3123:       /*         } */
                   3124:       /*         printf("\n"); */
                   3125:       /*       } */
                   3126:       /* } */
1.126     brouard  3127:       savm=oldm;
                   3128:       oldm=newm;
                   3129:     }
                   3130:     for(i=1; i<=nlstate+ndeath; i++)
                   3131:       for(j=1;j<=nlstate+ndeath;j++) {
1.218     brouard  3132:                                po[i][j][h]=newm[i][j];
                   3133:                                /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3134:       }
1.128     brouard  3135:     /*printf("h=%d ",h);*/
1.126     brouard  3136:   } /* end h */
1.218     brouard  3137:        /*     printf("\n H=%d \n",h); */
1.126     brouard  3138:   return po;
                   3139: }
                   3140: 
1.217     brouard  3141: /************* Higher Back Matrix Product ***************/
1.218     brouard  3142: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.222     brouard  3143: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij )
1.217     brouard  3144: {
1.218     brouard  3145:   /* Computes the transition matrix starting at age 'age' over
1.217     brouard  3146:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3147:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3148:      nhstepm*hstepm matrices.
                   3149:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3150:      (typically every 2 years instead of every month which is too big
1.217     brouard  3151:      for the memory).
1.218     brouard  3152:      Model is determined by parameters x and covariates have to be
                   3153:      included manually here.
1.217     brouard  3154: 
1.222     brouard  3155:   */
1.217     brouard  3156: 
                   3157:   int i, j, d, h, k;
                   3158:   double **out, cov[NCOVMAX+1];
                   3159:   double **newm;
                   3160:   double agexact;
                   3161:   double agebegin, ageend;
1.222     brouard  3162:   double **oldm, **savm;
1.217     brouard  3163: 
1.222     brouard  3164:   oldm=oldms;savm=savms;
1.217     brouard  3165:   /* Hstepm could be zero and should return the unit matrix */
                   3166:   for (i=1;i<=nlstate+ndeath;i++)
                   3167:     for (j=1;j<=nlstate+ndeath;j++){
                   3168:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3169:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3170:     }
                   3171:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3172:   for(h=1; h <=nhstepm; h++){
                   3173:     for(d=1; d <=hstepm; d++){
                   3174:       newm=savm;
                   3175:       /* Covariates have to be included here again */
                   3176:       cov[1]=1.;
                   3177:       agexact=age-((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
                   3178:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3179:       cov[2]=agexact;
                   3180:       if(nagesqr==1)
1.222     brouard  3181:        cov[3]= agexact*agexact;
1.218     brouard  3182:       for (k=1; k<=cptcovn;k++)
1.222     brouard  3183:        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
                   3184:       /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.217     brouard  3185:       for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
1.222     brouard  3186:        /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   3187:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3188:       /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
1.217     brouard  3189:       for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
1.222     brouard  3190:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3191:       /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
1.218     brouard  3192:                        
                   3193:                        
1.217     brouard  3194:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3195:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3196:       /* Careful transposed matrix */
1.222     brouard  3197:       /* age is in cov[2] */
1.218     brouard  3198:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3199:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3200:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3201:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3202:       /* if((int)age == 70){ */
                   3203:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3204:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3205:       /*         printf("%d pmmij ",i); */
                   3206:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3207:       /*           printf("%f ",pmmij[i][j]); */
                   3208:       /*         } */
                   3209:       /*         printf(" oldm "); */
                   3210:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3211:       /*           printf("%f ",oldm[i][j]); */
                   3212:       /*         } */
                   3213:       /*         printf("\n"); */
                   3214:       /*       } */
                   3215:       /* } */
                   3216:       savm=oldm;
                   3217:       oldm=newm;
                   3218:     }
                   3219:     for(i=1; i<=nlstate+ndeath; i++)
                   3220:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3221:        po[i][j][h]=newm[i][j];
                   3222:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.217     brouard  3223:       }
                   3224:     /*printf("h=%d ",h);*/
                   3225:   } /* end h */
1.222     brouard  3226:   /*     printf("\n H=%d \n",h); */
1.217     brouard  3227:   return po;
                   3228: }
                   3229: 
                   3230: 
1.162     brouard  3231: #ifdef NLOPT
                   3232:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3233:   double fret;
                   3234:   double *xt;
                   3235:   int j;
                   3236:   myfunc_data *d2 = (myfunc_data *) pd;
                   3237: /* xt = (p1-1); */
                   3238:   xt=vector(1,n); 
                   3239:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3240: 
                   3241:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3242:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3243:   printf("Function = %.12lf ",fret);
                   3244:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3245:   printf("\n");
                   3246:  free_vector(xt,1,n);
                   3247:   return fret;
                   3248: }
                   3249: #endif
1.126     brouard  3250: 
                   3251: /*************** log-likelihood *************/
                   3252: double func( double *x)
                   3253: {
1.226     brouard  3254:   int i, ii, j, k, mi, d, kk;
                   3255:   int ioffset=0;
                   3256:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3257:   double **out;
                   3258:   double lli; /* Individual log likelihood */
                   3259:   int s1, s2;
1.228     brouard  3260:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3261:   double bbh, survp;
                   3262:   long ipmx;
                   3263:   double agexact;
                   3264:   /*extern weight */
                   3265:   /* We are differentiating ll according to initial status */
                   3266:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3267:   /*for(i=1;i<imx;i++) 
                   3268:     printf(" %d\n",s[4][i]);
                   3269:   */
1.162     brouard  3270: 
1.226     brouard  3271:   ++countcallfunc;
1.162     brouard  3272: 
1.226     brouard  3273:   cov[1]=1.;
1.126     brouard  3274: 
1.226     brouard  3275:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3276:   ioffset=0;
1.226     brouard  3277:   if(mle==1){
                   3278:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3279:       /* Computes the values of the ncovmodel covariates of the model
                   3280:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3281:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3282:         to be observed in j being in i according to the model.
                   3283:       */
1.243     brouard  3284:       ioffset=2+nagesqr ;
1.233     brouard  3285:    /* Fixed */
1.234     brouard  3286:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3287:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3288:       }
1.226     brouard  3289:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3290:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3291:         has been calculated etc */
                   3292:       /* For an individual i, wav[i] gives the number of effective waves */
                   3293:       /* We compute the contribution to Likelihood of each effective transition
                   3294:         mw[mi][i] is real wave of the mi th effectve wave */
                   3295:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3296:         s2=s[mw[mi+1][i]][i];
                   3297:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3298:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3299:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3300:       */
                   3301:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3302:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3303:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3304:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3305:        }
                   3306:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3307:          for (j=1;j<=nlstate+ndeath;j++){
                   3308:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3309:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3310:          }
                   3311:        for(d=0; d<dh[mi][i]; d++){
                   3312:          newm=savm;
                   3313:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3314:          cov[2]=agexact;
                   3315:          if(nagesqr==1)
                   3316:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3317:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3318:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3319:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3320:          else
                   3321:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3322:          }
                   3323:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3324:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3325:          savm=oldm;
                   3326:          oldm=newm;
                   3327:        } /* end mult */
                   3328:        
                   3329:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3330:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3331:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3332:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3333:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3334:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3335:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3336:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3337:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3338:                                 * -stepm/2 to stepm/2 .
                   3339:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3340:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3341:                                 */
1.234     brouard  3342:        s1=s[mw[mi][i]][i];
                   3343:        s2=s[mw[mi+1][i]][i];
                   3344:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3345:        /* bias bh is positive if real duration
                   3346:         * is higher than the multiple of stepm and negative otherwise.
                   3347:         */
                   3348:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3349:        if( s2 > nlstate){ 
                   3350:          /* i.e. if s2 is a death state and if the date of death is known 
                   3351:             then the contribution to the likelihood is the probability to 
                   3352:             die between last step unit time and current  step unit time, 
                   3353:             which is also equal to probability to die before dh 
                   3354:             minus probability to die before dh-stepm . 
                   3355:             In version up to 0.92 likelihood was computed
                   3356:             as if date of death was unknown. Death was treated as any other
                   3357:             health state: the date of the interview describes the actual state
                   3358:             and not the date of a change in health state. The former idea was
                   3359:             to consider that at each interview the state was recorded
                   3360:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3361:             introduced the exact date of death then we should have modified
                   3362:             the contribution of an exact death to the likelihood. This new
                   3363:             contribution is smaller and very dependent of the step unit
                   3364:             stepm. It is no more the probability to die between last interview
                   3365:             and month of death but the probability to survive from last
                   3366:             interview up to one month before death multiplied by the
                   3367:             probability to die within a month. Thanks to Chris
                   3368:             Jackson for correcting this bug.  Former versions increased
                   3369:             mortality artificially. The bad side is that we add another loop
                   3370:             which slows down the processing. The difference can be up to 10%
                   3371:             lower mortality.
                   3372:          */
                   3373:          /* If, at the beginning of the maximization mostly, the
                   3374:             cumulative probability or probability to be dead is
                   3375:             constant (ie = 1) over time d, the difference is equal to
                   3376:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3377:             s1 at precedent wave, to be dead a month before current
                   3378:             wave is equal to probability, being at state s1 at
                   3379:             precedent wave, to be dead at mont of the current
                   3380:             wave. Then the observed probability (that this person died)
                   3381:             is null according to current estimated parameter. In fact,
                   3382:             it should be very low but not zero otherwise the log go to
                   3383:             infinity.
                   3384:          */
1.183     brouard  3385: /* #ifdef INFINITYORIGINAL */
                   3386: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3387: /* #else */
                   3388: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3389: /*         lli=log(mytinydouble); */
                   3390: /*       else */
                   3391: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3392: /* #endif */
1.226     brouard  3393:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3394:          
1.226     brouard  3395:        } else if  ( s2==-1 ) { /* alive */
                   3396:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3397:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3398:          /*survp += out[s1][j]; */
                   3399:          lli= log(survp);
                   3400:        }
                   3401:        else if  (s2==-4) { 
                   3402:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3403:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3404:          lli= log(survp); 
                   3405:        } 
                   3406:        else if  (s2==-5) { 
                   3407:          for (j=1,survp=0. ; j<=2; j++)  
                   3408:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3409:          lli= log(survp); 
                   3410:        } 
                   3411:        else{
                   3412:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3413:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3414:        } 
                   3415:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3416:        /*if(lli ==000.0)*/
                   3417:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3418:        ipmx +=1;
                   3419:        sw += weight[i];
                   3420:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3421:        /* if (lli < log(mytinydouble)){ */
                   3422:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3423:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3424:        /* } */
                   3425:       } /* end of wave */
                   3426:     } /* end of individual */
                   3427:   }  else if(mle==2){
                   3428:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3429:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3430:       for(mi=1; mi<= wav[i]-1; mi++){
                   3431:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3432:          for (j=1;j<=nlstate+ndeath;j++){
                   3433:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3434:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3435:          }
                   3436:        for(d=0; d<=dh[mi][i]; d++){
                   3437:          newm=savm;
                   3438:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3439:          cov[2]=agexact;
                   3440:          if(nagesqr==1)
                   3441:            cov[3]= agexact*agexact;
                   3442:          for (kk=1; kk<=cptcovage;kk++) {
                   3443:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3444:          }
                   3445:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3446:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3447:          savm=oldm;
                   3448:          oldm=newm;
                   3449:        } /* end mult */
                   3450:       
                   3451:        s1=s[mw[mi][i]][i];
                   3452:        s2=s[mw[mi+1][i]][i];
                   3453:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3454:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3455:        ipmx +=1;
                   3456:        sw += weight[i];
                   3457:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3458:       } /* end of wave */
                   3459:     } /* end of individual */
                   3460:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3461:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3462:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3463:       for(mi=1; mi<= wav[i]-1; mi++){
                   3464:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3465:          for (j=1;j<=nlstate+ndeath;j++){
                   3466:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3467:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3468:          }
                   3469:        for(d=0; d<dh[mi][i]; d++){
                   3470:          newm=savm;
                   3471:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3472:          cov[2]=agexact;
                   3473:          if(nagesqr==1)
                   3474:            cov[3]= agexact*agexact;
                   3475:          for (kk=1; kk<=cptcovage;kk++) {
                   3476:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3477:          }
                   3478:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3479:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3480:          savm=oldm;
                   3481:          oldm=newm;
                   3482:        } /* end mult */
                   3483:       
                   3484:        s1=s[mw[mi][i]][i];
                   3485:        s2=s[mw[mi+1][i]][i];
                   3486:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3487:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3488:        ipmx +=1;
                   3489:        sw += weight[i];
                   3490:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3491:       } /* end of wave */
                   3492:     } /* end of individual */
                   3493:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3494:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3495:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3496:       for(mi=1; mi<= wav[i]-1; mi++){
                   3497:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3498:          for (j=1;j<=nlstate+ndeath;j++){
                   3499:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3500:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3501:          }
                   3502:        for(d=0; d<dh[mi][i]; d++){
                   3503:          newm=savm;
                   3504:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3505:          cov[2]=agexact;
                   3506:          if(nagesqr==1)
                   3507:            cov[3]= agexact*agexact;
                   3508:          for (kk=1; kk<=cptcovage;kk++) {
                   3509:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3510:          }
1.126     brouard  3511:        
1.226     brouard  3512:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3513:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3514:          savm=oldm;
                   3515:          oldm=newm;
                   3516:        } /* end mult */
                   3517:       
                   3518:        s1=s[mw[mi][i]][i];
                   3519:        s2=s[mw[mi+1][i]][i];
                   3520:        if( s2 > nlstate){ 
                   3521:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3522:        } else if  ( s2==-1 ) { /* alive */
                   3523:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3524:            survp += out[s1][j];
                   3525:          lli= log(survp);
                   3526:        }else{
                   3527:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3528:        }
                   3529:        ipmx +=1;
                   3530:        sw += weight[i];
                   3531:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3532: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3533:       } /* end of wave */
                   3534:     } /* end of individual */
                   3535:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3536:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3537:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3538:       for(mi=1; mi<= wav[i]-1; mi++){
                   3539:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3540:          for (j=1;j<=nlstate+ndeath;j++){
                   3541:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3542:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3543:          }
                   3544:        for(d=0; d<dh[mi][i]; d++){
                   3545:          newm=savm;
                   3546:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3547:          cov[2]=agexact;
                   3548:          if(nagesqr==1)
                   3549:            cov[3]= agexact*agexact;
                   3550:          for (kk=1; kk<=cptcovage;kk++) {
                   3551:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3552:          }
1.126     brouard  3553:        
1.226     brouard  3554:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3555:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3556:          savm=oldm;
                   3557:          oldm=newm;
                   3558:        } /* end mult */
                   3559:       
                   3560:        s1=s[mw[mi][i]][i];
                   3561:        s2=s[mw[mi+1][i]][i];
                   3562:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3563:        ipmx +=1;
                   3564:        sw += weight[i];
                   3565:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3566:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3567:       } /* end of wave */
                   3568:     } /* end of individual */
                   3569:   } /* End of if */
                   3570:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3571:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3572:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3573:   return -l;
1.126     brouard  3574: }
                   3575: 
                   3576: /*************** log-likelihood *************/
                   3577: double funcone( double *x)
                   3578: {
1.228     brouard  3579:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3580:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3581:   int ioffset=0;
1.131     brouard  3582:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3583:   double **out;
                   3584:   double lli; /* Individual log likelihood */
                   3585:   double llt;
                   3586:   int s1, s2;
1.228     brouard  3587:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3588: 
1.126     brouard  3589:   double bbh, survp;
1.187     brouard  3590:   double agexact;
1.214     brouard  3591:   double agebegin, ageend;
1.126     brouard  3592:   /*extern weight */
                   3593:   /* We are differentiating ll according to initial status */
                   3594:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3595:   /*for(i=1;i<imx;i++) 
                   3596:     printf(" %d\n",s[4][i]);
                   3597:   */
                   3598:   cov[1]=1.;
                   3599: 
                   3600:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3601:   ioffset=0;
                   3602:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3603:     /* ioffset=2+nagesqr+cptcovage; */
                   3604:     ioffset=2+nagesqr;
1.232     brouard  3605:     /* Fixed */
1.224     brouard  3606:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3607:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3608:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3609:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3610: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3611: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3612: /*    cov[2+6]=covar[2][i]; V2  */
                   3613: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3614: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3615: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3616: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3617: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3618: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3619:     }
1.232     brouard  3620:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3621:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3622:     /* } */
1.231     brouard  3623:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3624:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3625:     /* } */
1.225     brouard  3626:     
1.233     brouard  3627: 
                   3628:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3629:     /* Wave varying (but not age varying) */
                   3630:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3631:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3632:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3633:       }
1.232     brouard  3634:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3635:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3636:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3637:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3638:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3639:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3640:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3641:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3642:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3643:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3644:       /* } */
1.126     brouard  3645:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3646:        for (j=1;j<=nlstate+ndeath;j++){
                   3647:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3648:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3649:        }
1.214     brouard  3650:       
                   3651:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3652:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3653:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3654:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3655:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3656:          and mw[mi+1][i]. dh depends on stepm.*/
                   3657:        newm=savm;
1.247     brouard  3658:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3659:        cov[2]=agexact;
                   3660:        if(nagesqr==1)
                   3661:          cov[3]= agexact*agexact;
                   3662:        for (kk=1; kk<=cptcovage;kk++) {
                   3663:          if(!FixedV[Tvar[Tage[kk]]])
                   3664:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3665:          else
                   3666:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3667:        }
                   3668:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3669:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3670:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3671:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3672:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3673:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3674:        savm=oldm;
                   3675:        oldm=newm;
1.126     brouard  3676:       } /* end mult */
                   3677:       
                   3678:       s1=s[mw[mi][i]][i];
                   3679:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3680:       /* if(s2==-1){ */
                   3681:       /*       printf(" s1=%d, s2=%d i=%d \n", s1, s2, i); */
                   3682:       /*       /\* exit(1); *\/ */
                   3683:       /* } */
1.126     brouard  3684:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3685:       /* bias is positive if real duration
                   3686:        * is higher than the multiple of stepm and negative otherwise.
                   3687:        */
                   3688:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3689:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3690:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3691:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3692:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3693:        lli= log(survp);
1.126     brouard  3694:       }else if (mle==1){
1.242     brouard  3695:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3696:       } else if(mle==2){
1.242     brouard  3697:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3698:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3699:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3700:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3701:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3702:       } else{  /* mle=0 back to 1 */
1.242     brouard  3703:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3704:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3705:       } /* End of if */
                   3706:       ipmx +=1;
                   3707:       sw += weight[i];
                   3708:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3709:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3710:       if(globpr){
1.246     brouard  3711:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3712:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3713:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                   3714:                2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
                   3715:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3716:          llt +=ll[k]*gipmx/gsw;
                   3717:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3718:        }
                   3719:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3720:       }
1.232     brouard  3721:        } /* end of wave */
                   3722: } /* end of individual */
                   3723: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3724: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3725: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3726: if(globpr==0){ /* First time we count the contributions and weights */
                   3727:        gipmx=ipmx;
                   3728:        gsw=sw;
                   3729: }
                   3730: return -l;
1.126     brouard  3731: }
                   3732: 
                   3733: 
                   3734: /*************** function likelione ***********/
                   3735: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3736: {
                   3737:   /* This routine should help understanding what is done with 
                   3738:      the selection of individuals/waves and
                   3739:      to check the exact contribution to the likelihood.
                   3740:      Plotting could be done.
                   3741:    */
                   3742:   int k;
                   3743: 
                   3744:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3745:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3746:     strcat(fileresilk,fileresu);
1.126     brouard  3747:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3748:       printf("Problem with resultfile: %s\n", fileresilk);
                   3749:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3750:     }
1.214     brouard  3751:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3752:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3753:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3754:     for(k=1; k<=nlstate; k++) 
                   3755:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3756:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3757:   }
                   3758: 
                   3759:   *fretone=(*funcone)(p);
                   3760:   if(*globpri !=0){
                   3761:     fclose(ficresilk);
1.205     brouard  3762:     if (mle ==0)
                   3763:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3764:     else if(mle >=1)
                   3765:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3766:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3767:     
1.208     brouard  3768:       
                   3769:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3770:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3771: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3772:     }
1.207     brouard  3773:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3774: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3775:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3776: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3777:     fflush(fichtm);
1.205     brouard  3778:   }
1.126     brouard  3779:   return;
                   3780: }
                   3781: 
                   3782: 
                   3783: /*********** Maximum Likelihood Estimation ***************/
                   3784: 
                   3785: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3786: {
1.165     brouard  3787:   int i,j, iter=0;
1.126     brouard  3788:   double **xi;
                   3789:   double fret;
                   3790:   double fretone; /* Only one call to likelihood */
                   3791:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3792: 
                   3793: #ifdef NLOPT
                   3794:   int creturn;
                   3795:   nlopt_opt opt;
                   3796:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3797:   double *lb;
                   3798:   double minf; /* the minimum objective value, upon return */
                   3799:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3800:   myfunc_data dinst, *d = &dinst;
                   3801: #endif
                   3802: 
                   3803: 
1.126     brouard  3804:   xi=matrix(1,npar,1,npar);
                   3805:   for (i=1;i<=npar;i++)
                   3806:     for (j=1;j<=npar;j++)
                   3807:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3808:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3809:   strcpy(filerespow,"POW_"); 
1.126     brouard  3810:   strcat(filerespow,fileres);
                   3811:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3812:     printf("Problem with resultfile: %s\n", filerespow);
                   3813:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3814:   }
                   3815:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3816:   for (i=1;i<=nlstate;i++)
                   3817:     for(j=1;j<=nlstate+ndeath;j++)
                   3818:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3819:   fprintf(ficrespow,"\n");
1.162     brouard  3820: #ifdef POWELL
1.126     brouard  3821:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3822: #endif
1.126     brouard  3823: 
1.162     brouard  3824: #ifdef NLOPT
                   3825: #ifdef NEWUOA
                   3826:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3827: #else
                   3828:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3829: #endif
                   3830:   lb=vector(0,npar-1);
                   3831:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3832:   nlopt_set_lower_bounds(opt, lb);
                   3833:   nlopt_set_initial_step1(opt, 0.1);
                   3834:   
                   3835:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3836:   d->function = func;
                   3837:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3838:   nlopt_set_min_objective(opt, myfunc, d);
                   3839:   nlopt_set_xtol_rel(opt, ftol);
                   3840:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3841:     printf("nlopt failed! %d\n",creturn); 
                   3842:   }
                   3843:   else {
                   3844:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3845:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3846:     iter=1; /* not equal */
                   3847:   }
                   3848:   nlopt_destroy(opt);
                   3849: #endif
1.126     brouard  3850:   free_matrix(xi,1,npar,1,npar);
                   3851:   fclose(ficrespow);
1.203     brouard  3852:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3853:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3854:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3855: 
                   3856: }
                   3857: 
                   3858: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3859: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3860: {
                   3861:   double  **a,**y,*x,pd;
1.203     brouard  3862:   /* double **hess; */
1.164     brouard  3863:   int i, j;
1.126     brouard  3864:   int *indx;
                   3865: 
                   3866:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3867:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3868:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3869:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3870:   double gompertz(double p[]);
1.203     brouard  3871:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3872: 
                   3873:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3874:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3875:   for (i=1;i<=npar;i++){
1.203     brouard  3876:     printf("%d-",i);fflush(stdout);
                   3877:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3878:    
                   3879:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3880:     
                   3881:     /*  printf(" %f ",p[i]);
                   3882:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3883:   }
                   3884:   
                   3885:   for (i=1;i<=npar;i++) {
                   3886:     for (j=1;j<=npar;j++)  {
                   3887:       if (j>i) { 
1.203     brouard  3888:        printf(".%d-%d",i,j);fflush(stdout);
                   3889:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3890:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3891:        
                   3892:        hess[j][i]=hess[i][j];    
                   3893:        /*printf(" %lf ",hess[i][j]);*/
                   3894:       }
                   3895:     }
                   3896:   }
                   3897:   printf("\n");
                   3898:   fprintf(ficlog,"\n");
                   3899: 
                   3900:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3901:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3902:   
                   3903:   a=matrix(1,npar,1,npar);
                   3904:   y=matrix(1,npar,1,npar);
                   3905:   x=vector(1,npar);
                   3906:   indx=ivector(1,npar);
                   3907:   for (i=1;i<=npar;i++)
                   3908:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3909:   ludcmp(a,npar,indx,&pd);
                   3910: 
                   3911:   for (j=1;j<=npar;j++) {
                   3912:     for (i=1;i<=npar;i++) x[i]=0;
                   3913:     x[j]=1;
                   3914:     lubksb(a,npar,indx,x);
                   3915:     for (i=1;i<=npar;i++){ 
                   3916:       matcov[i][j]=x[i];
                   3917:     }
                   3918:   }
                   3919: 
                   3920:   printf("\n#Hessian matrix#\n");
                   3921:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3922:   for (i=1;i<=npar;i++) { 
                   3923:     for (j=1;j<=npar;j++) { 
1.203     brouard  3924:       printf("%.6e ",hess[i][j]);
                   3925:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  3926:     }
                   3927:     printf("\n");
                   3928:     fprintf(ficlog,"\n");
                   3929:   }
                   3930: 
1.203     brouard  3931:   /* printf("\n#Covariance matrix#\n"); */
                   3932:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   3933:   /* for (i=1;i<=npar;i++) {  */
                   3934:   /*   for (j=1;j<=npar;j++) {  */
                   3935:   /*     printf("%.6e ",matcov[i][j]); */
                   3936:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   3937:   /*   } */
                   3938:   /*   printf("\n"); */
                   3939:   /*   fprintf(ficlog,"\n"); */
                   3940:   /* } */
                   3941: 
1.126     brouard  3942:   /* Recompute Inverse */
1.203     brouard  3943:   /* for (i=1;i<=npar;i++) */
                   3944:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   3945:   /* ludcmp(a,npar,indx,&pd); */
                   3946: 
                   3947:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   3948: 
                   3949:   /* for (j=1;j<=npar;j++) { */
                   3950:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   3951:   /*   x[j]=1; */
                   3952:   /*   lubksb(a,npar,indx,x); */
                   3953:   /*   for (i=1;i<=npar;i++){  */
                   3954:   /*     y[i][j]=x[i]; */
                   3955:   /*     printf("%.3e ",y[i][j]); */
                   3956:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   3957:   /*   } */
                   3958:   /*   printf("\n"); */
                   3959:   /*   fprintf(ficlog,"\n"); */
                   3960:   /* } */
                   3961: 
                   3962:   /* Verifying the inverse matrix */
                   3963: #ifdef DEBUGHESS
                   3964:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  3965: 
1.203     brouard  3966:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   3967:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  3968: 
                   3969:   for (j=1;j<=npar;j++) {
                   3970:     for (i=1;i<=npar;i++){ 
1.203     brouard  3971:       printf("%.2f ",y[i][j]);
                   3972:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  3973:     }
                   3974:     printf("\n");
                   3975:     fprintf(ficlog,"\n");
                   3976:   }
1.203     brouard  3977: #endif
1.126     brouard  3978: 
                   3979:   free_matrix(a,1,npar,1,npar);
                   3980:   free_matrix(y,1,npar,1,npar);
                   3981:   free_vector(x,1,npar);
                   3982:   free_ivector(indx,1,npar);
1.203     brouard  3983:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  3984: 
                   3985: 
                   3986: }
                   3987: 
                   3988: /*************** hessian matrix ****************/
                   3989: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  3990: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  3991:   int i;
                   3992:   int l=1, lmax=20;
1.203     brouard  3993:   double k1,k2, res, fx;
1.132     brouard  3994:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  3995:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   3996:   int k=0,kmax=10;
                   3997:   double l1;
                   3998: 
                   3999:   fx=func(x);
                   4000:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4001:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4002:     l1=pow(10,l);
                   4003:     delts=delt;
                   4004:     for(k=1 ; k <kmax; k=k+1){
                   4005:       delt = delta*(l1*k);
                   4006:       p2[theta]=x[theta] +delt;
1.145     brouard  4007:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4008:       p2[theta]=x[theta]-delt;
                   4009:       k2=func(p2)-fx;
                   4010:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4011:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4012:       
1.203     brouard  4013: #ifdef DEBUGHESSII
1.126     brouard  4014:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4015:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4016: #endif
                   4017:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4018:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4019:        k=kmax;
                   4020:       }
                   4021:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4022:        k=kmax; l=lmax*10;
1.126     brouard  4023:       }
                   4024:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4025:        delts=delt;
                   4026:       }
1.203     brouard  4027:     } /* End loop k */
1.126     brouard  4028:   }
                   4029:   delti[theta]=delts;
                   4030:   return res; 
                   4031:   
                   4032: }
                   4033: 
1.203     brouard  4034: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4035: {
                   4036:   int i;
1.164     brouard  4037:   int l=1, lmax=20;
1.126     brouard  4038:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4039:   double p2[MAXPARM+1];
1.203     brouard  4040:   int k, kmax=1;
                   4041:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4042: 
                   4043:   int firstime=0;
1.203     brouard  4044:   
1.126     brouard  4045:   fx=func(x);
1.203     brouard  4046:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4047:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4048:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4049:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4050:     k1=func(p2)-fx;
                   4051:   
1.203     brouard  4052:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4053:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4054:     k2=func(p2)-fx;
                   4055:   
1.203     brouard  4056:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4057:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4058:     k3=func(p2)-fx;
                   4059:   
1.203     brouard  4060:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4061:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4062:     k4=func(p2)-fx;
1.203     brouard  4063:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4064:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4065:       firstime=1;
1.203     brouard  4066:       kmax=kmax+10;
1.208     brouard  4067:     }
                   4068:     if(kmax >=10 || firstime ==1){
1.246     brouard  4069:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4070:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4071:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4072:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4073:     }
                   4074: #ifdef DEBUGHESSIJ
                   4075:     v1=hess[thetai][thetai];
                   4076:     v2=hess[thetaj][thetaj];
                   4077:     cv12=res;
                   4078:     /* Computing eigen value of Hessian matrix */
                   4079:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4080:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4081:     if ((lc2 <0) || (lc1 <0) ){
                   4082:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4083:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4084:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4085:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4086:     }
1.126     brouard  4087: #endif
                   4088:   }
                   4089:   return res;
                   4090: }
                   4091: 
1.203     brouard  4092:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4093: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4094: /* { */
                   4095: /*   int i; */
                   4096: /*   int l=1, lmax=20; */
                   4097: /*   double k1,k2,k3,k4,res,fx; */
                   4098: /*   double p2[MAXPARM+1]; */
                   4099: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4100: /*   int k=0,kmax=10; */
                   4101: /*   double l1; */
                   4102:   
                   4103: /*   fx=func(x); */
                   4104: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4105: /*     l1=pow(10,l); */
                   4106: /*     delts=delt; */
                   4107: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4108: /*       delt = delti*(l1*k); */
                   4109: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4110: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4111: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4112: /*       k1=func(p2)-fx; */
                   4113:       
                   4114: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4115: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4116: /*       k2=func(p2)-fx; */
                   4117:       
                   4118: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4119: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4120: /*       k3=func(p2)-fx; */
                   4121:       
                   4122: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4123: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4124: /*       k4=func(p2)-fx; */
                   4125: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4126: /* #ifdef DEBUGHESSIJ */
                   4127: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4128: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4129: /* #endif */
                   4130: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4131: /*     k=kmax; */
                   4132: /*       } */
                   4133: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4134: /*     k=kmax; l=lmax*10; */
                   4135: /*       } */
                   4136: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4137: /*     delts=delt; */
                   4138: /*       } */
                   4139: /*     } /\* End loop k *\/ */
                   4140: /*   } */
                   4141: /*   delti[theta]=delts; */
                   4142: /*   return res;  */
                   4143: /* } */
                   4144: 
                   4145: 
1.126     brouard  4146: /************** Inverse of matrix **************/
                   4147: void ludcmp(double **a, int n, int *indx, double *d) 
                   4148: { 
                   4149:   int i,imax,j,k; 
                   4150:   double big,dum,sum,temp; 
                   4151:   double *vv; 
                   4152:  
                   4153:   vv=vector(1,n); 
                   4154:   *d=1.0; 
                   4155:   for (i=1;i<=n;i++) { 
                   4156:     big=0.0; 
                   4157:     for (j=1;j<=n;j++) 
                   4158:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4159:     if (big == 0.0){
                   4160:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4161:       for (j=1;j<=n;j++) {
                   4162:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4163:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4164:       }
                   4165:       fflush(ficlog);
                   4166:       fclose(ficlog);
                   4167:       nrerror("Singular matrix in routine ludcmp"); 
                   4168:     }
1.126     brouard  4169:     vv[i]=1.0/big; 
                   4170:   } 
                   4171:   for (j=1;j<=n;j++) { 
                   4172:     for (i=1;i<j;i++) { 
                   4173:       sum=a[i][j]; 
                   4174:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4175:       a[i][j]=sum; 
                   4176:     } 
                   4177:     big=0.0; 
                   4178:     for (i=j;i<=n;i++) { 
                   4179:       sum=a[i][j]; 
                   4180:       for (k=1;k<j;k++) 
                   4181:        sum -= a[i][k]*a[k][j]; 
                   4182:       a[i][j]=sum; 
                   4183:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4184:        big=dum; 
                   4185:        imax=i; 
                   4186:       } 
                   4187:     } 
                   4188:     if (j != imax) { 
                   4189:       for (k=1;k<=n;k++) { 
                   4190:        dum=a[imax][k]; 
                   4191:        a[imax][k]=a[j][k]; 
                   4192:        a[j][k]=dum; 
                   4193:       } 
                   4194:       *d = -(*d); 
                   4195:       vv[imax]=vv[j]; 
                   4196:     } 
                   4197:     indx[j]=imax; 
                   4198:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4199:     if (j != n) { 
                   4200:       dum=1.0/(a[j][j]); 
                   4201:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4202:     } 
                   4203:   } 
                   4204:   free_vector(vv,1,n);  /* Doesn't work */
                   4205: ;
                   4206: } 
                   4207: 
                   4208: void lubksb(double **a, int n, int *indx, double b[]) 
                   4209: { 
                   4210:   int i,ii=0,ip,j; 
                   4211:   double sum; 
                   4212:  
                   4213:   for (i=1;i<=n;i++) { 
                   4214:     ip=indx[i]; 
                   4215:     sum=b[ip]; 
                   4216:     b[ip]=b[i]; 
                   4217:     if (ii) 
                   4218:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4219:     else if (sum) ii=i; 
                   4220:     b[i]=sum; 
                   4221:   } 
                   4222:   for (i=n;i>=1;i--) { 
                   4223:     sum=b[i]; 
                   4224:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4225:     b[i]=sum/a[i][i]; 
                   4226:   } 
                   4227: } 
                   4228: 
                   4229: void pstamp(FILE *fichier)
                   4230: {
1.196     brouard  4231:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4232: }
                   4233: 
1.253     brouard  4234: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4235: 
                   4236:   /* y=a+bx regression */
                   4237:   double   sumx = 0.0;                        /* sum of x                      */
                   4238:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4239:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4240:   double   sumy = 0.0;                        /* sum of y                      */
                   4241:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4242:   double   sume2; /* sum of square or residuals */
                   4243:   double yhat;
                   4244:   
                   4245:   double denom=0;
                   4246:   int i;
                   4247:   int ne=*no;
                   4248:   
                   4249:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4250:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4251:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4252:       continue;
                   4253:     }
                   4254:     ne=ne+1;
                   4255:     sumx  += x[i];       
                   4256:     sumx2 += x[i]*x[i];  
                   4257:     sumxy += x[i] * y[i];
                   4258:     sumy  += y[i];      
                   4259:     sumy2 += y[i]*y[i]; 
                   4260:     denom = (ne * sumx2 - sumx*sumx);
                   4261:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4262:   } 
                   4263:   
                   4264:   denom = (ne * sumx2 - sumx*sumx);
                   4265:   if (denom == 0) {
                   4266:     // vertical, slope m is infinity
                   4267:     *b = INFINITY;
                   4268:     *a = 0;
                   4269:     if (r) *r = 0;
                   4270:     return 1;
                   4271:   }
                   4272:   
                   4273:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4274:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4275:   if (r!=NULL) {
                   4276:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4277:       sqrt((sumx2 - sumx*sumx/ne) *
                   4278:           (sumy2 - sumy*sumy/ne));
                   4279:   }
                   4280:   *no=ne;
                   4281:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4282:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4283:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4284:       continue;
                   4285:     }
                   4286:     ne=ne+1;
                   4287:     yhat = y[i] - *a -*b* x[i];
                   4288:     sume2  += yhat * yhat ;       
                   4289:     
                   4290:     denom = (ne * sumx2 - sumx*sumx);
                   4291:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4292:   } 
                   4293:   *sb = sqrt(sume2/(ne-2)/(sumx2 - sumx * sumx /ne));
                   4294:   *sa= *sb * sqrt(sumx2/ne);
                   4295:   
                   4296:   return 0; 
                   4297: }
                   4298: 
1.126     brouard  4299: /************ Frequencies ********************/
1.251     brouard  4300: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4301:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4302:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4303: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4304:   
1.253     brouard  4305:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0;
1.226     brouard  4306:   int iind=0, iage=0;
                   4307:   int mi; /* Effective wave */
                   4308:   int first;
                   4309:   double ***freq; /* Frequencies */
1.253     brouard  4310:   double *x, *y, a,b,r, sa, sb; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4311:   int no;
1.226     brouard  4312:   double *meanq;
                   4313:   double **meanqt;
                   4314:   double *pp, **prop, *posprop, *pospropt;
                   4315:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4316:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4317:   double agebegin, ageend;
                   4318:     
                   4319:   pp=vector(1,nlstate);
1.251     brouard  4320:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4321:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4322:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4323:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4324:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4325:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4326:   strcpy(fileresp,"P_");
                   4327:   strcat(fileresp,fileresu);
                   4328:   /*strcat(fileresphtm,fileresu);*/
                   4329:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4330:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4331:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4332:     exit(0);
                   4333:   }
1.240     brouard  4334:   
1.226     brouard  4335:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4336:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4337:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4338:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4339:     fflush(ficlog);
                   4340:     exit(70); 
                   4341:   }
                   4342:   else{
                   4343:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4344: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4345: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4346:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4347:   }
1.237     brouard  4348:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4349:   
1.226     brouard  4350:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4351:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4352:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4353:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4354:     fflush(ficlog);
                   4355:     exit(70); 
1.240     brouard  4356:   } else{
1.226     brouard  4357:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4358: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4359: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4360:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4361:   }
1.240     brouard  4362:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4363:   
1.253     brouard  4364:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4365:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4366:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4367:   j1=0;
1.126     brouard  4368:   
1.227     brouard  4369:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4370:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4371:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4372:   
                   4373:   
1.226     brouard  4374:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4375:      reference=low_education V1=0,V2=0
                   4376:      med_educ                V1=1 V2=0, 
                   4377:      high_educ               V1=0 V2=1
                   4378:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4379:   */
1.249     brouard  4380:   dateintsum=0;
                   4381:   k2cpt=0;
                   4382: 
1.253     brouard  4383:   if(cptcoveff == 0 )
                   4384:     nl=1;  /* Constant model only */
                   4385:   else
                   4386:     nl=2;
                   4387:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4388:     if(nj==1)
                   4389:       j=0;  /* First pass for the constant */
                   4390:     else
                   4391:       j=cptcoveff; /* Other passes for the covariate values */
1.251     brouard  4392:     first=1;
                   4393:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on covariates combination in order of model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
                   4394:       posproptt=0.;
                   4395:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4396:        scanf("%d", i);*/
                   4397:       for (i=-5; i<=nlstate+ndeath; i++)  
                   4398:        for (jk=-5; jk<=nlstate+ndeath; jk++)  
                   4399:          for(m=iagemin; m <= iagemax+3; m++)
                   4400:            freq[i][jk][m]=0;
                   4401:       
                   4402:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4403:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4404:          prop[i][m]=0;
                   4405:        posprop[i]=0;
                   4406:        pospropt[i]=0;
                   4407:       }
                   4408:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4409:       /*   meanq[z1]+=0.; */
                   4410:       /*   for(m=1;m<=lastpass;m++){ */
                   4411:       /*       meanqt[m][z1]=0.; */
                   4412:       /*   } */
                   4413:       /* } */
                   4414:       
                   4415:       /* dateintsum=0; */
                   4416:       /* k2cpt=0; */
                   4417:       
                   4418:       /* For that combination of covariate j1, we count and print the frequencies in one pass */
                   4419:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4420:        bool=1;
                   4421:        if(j !=0){
                   4422:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4423:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4424:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4425:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4426:              /* } */
                   4427:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4428:                /* if(Tvaraff[z1] ==-20){ */
                   4429:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4430:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4431:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4432:                /* }else  */
                   4433:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
                   4434:                  /* Tests if this individual iind responded to combination j1 (V4=1 V3=0) */
                   4435:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4436:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4437:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4438:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4439:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4440:                } /* Onlyf fixed */
                   4441:              } /* end z1 */
                   4442:            } /* cptcovn > 0 */
                   4443:          } /* end any */
                   4444:        }/* end j==0 */
                   4445:        if (bool==1){ /* We selected an individual iind satisfying combination j1 or all fixed */
                   4446:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4447:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4448:            m=mw[mi][iind];
                   4449:            if(j!=0){
                   4450:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4451:                for (z1=1; z1<=cptcoveff; z1++) {
                   4452:                  if( Fixed[Tmodelind[z1]]==1){
                   4453:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4454:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4455:                                                                                      value is -1, we don't select. It differs from the 
                   4456:                                                                                      constant and age model which counts them. */
                   4457:                      bool=0; /* not selected */
                   4458:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4459:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4460:                      bool=0;
                   4461:                    }
                   4462:                  }
                   4463:                }
                   4464:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4465:            } /* end j==0 */
                   4466:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4467:            if(bool==1){
                   4468:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4469:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4470:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4471:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4472:              if(m >=firstpass && m <=lastpass){
                   4473:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4474:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4475:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4476:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4477:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4478:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4479:                if (m<lastpass) {
                   4480:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4481:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4482:                  if(s[m][iind]==-1)
                   4483:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4484:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4485:                  /* if((int)agev[m][iind] == 55) */
                   4486:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4487:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4488:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4489:                }
1.251     brouard  4490:              } /* end if between passes */  
                   4491:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4492:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4493:                k2cpt++;
                   4494:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4495:              }
1.251     brouard  4496:            }else{
                   4497:              bool=1;
                   4498:            }/* end bool 2 */
                   4499:          } /* end m */
                   4500:        } /* end bool */
                   4501:       } /* end iind = 1 to imx */
                   4502:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4503:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4504:       
                   4505:       
                   4506:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
                   4507:       pstamp(ficresp);
                   4508:       if  (cptcoveff>0 && j!=0){
                   4509:        printf( "\n#********** Variable "); 
                   4510:        fprintf(ficresp, "\n#********** Variable "); 
                   4511:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4512:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4513:        fprintf(ficlog, "\n#********** Variable "); 
                   4514:        for (z1=1; z1<=cptcoveff; z1++){
                   4515:          if(!FixedV[Tvaraff[z1]]){
                   4516:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4517:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4518:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4519:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4520:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4521:          }else{
1.251     brouard  4522:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4523:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4524:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4525:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4526:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4527:          }
                   4528:        }
                   4529:        printf( "**********\n#");
                   4530:        fprintf(ficresp, "**********\n#");
                   4531:        fprintf(ficresphtm, "**********</h3>\n");
                   4532:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4533:        fprintf(ficlog, "**********\n");
                   4534:       }
                   4535:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
                   4536:       for(i=1; i<=nlstate;i++) {
                   4537:        fprintf(ficresp, " Age Prev(%d)  N(%d)  N  ",i,i);
                   4538:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4539:       }
                   4540:       fprintf(ficresp, "\n");
                   4541:       fprintf(ficresphtm, "\n");
                   4542:       
                   4543:       /* Header of frequency table by age */
                   4544:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4545:       fprintf(ficresphtmfr,"<th>Age</th> ");
                   4546:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4547:        for(m=-1; m <=nlstate+ndeath; m++){
                   4548:          if(jk!=0 && m!=0)
                   4549:            fprintf(ficresphtmfr,"<th>%d%d</th> ",jk,m);
1.240     brouard  4550:        }
1.226     brouard  4551:       }
1.251     brouard  4552:       fprintf(ficresphtmfr, "\n");
                   4553:     
                   4554:       /* For each age */
                   4555:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4556:        fprintf(ficresphtm,"<tr>");
                   4557:        if(iage==iagemax+1){
                   4558:          fprintf(ficlog,"1");
                   4559:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4560:        }else if(iage==iagemax+2){
                   4561:          fprintf(ficlog,"0");
                   4562:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4563:        }else if(iage==iagemax+3){
                   4564:          fprintf(ficlog,"Total");
                   4565:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4566:        }else{
1.240     brouard  4567:          if(first==1){
1.251     brouard  4568:            first=0;
                   4569:            printf("See log file for details...\n");
                   4570:          }
                   4571:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4572:          fprintf(ficlog,"Age %d", iage);
                   4573:        }
                   4574:        for(jk=1; jk <=nlstate ; jk++){
                   4575:          for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
                   4576:            pp[jk] += freq[jk][m][iage]; 
                   4577:        }
                   4578:        for(jk=1; jk <=nlstate ; jk++){
                   4579:          for(m=-1, pos=0; m <=0 ; m++)
                   4580:            pos += freq[jk][m][iage];
                   4581:          if(pp[jk]>=1.e-10){
                   4582:            if(first==1){
                   4583:              printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4584:            }
                   4585:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
                   4586:          }else{
                   4587:            if(first==1)
                   4588:              printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
                   4589:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
1.240     brouard  4590:          }
                   4591:        }
                   4592:       
1.251     brouard  4593:        for(jk=1; jk <=nlstate ; jk++){ 
                   4594:          /* posprop[jk]=0; */
                   4595:          for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4596:            pp[jk] += freq[jk][m][iage];
                   4597:        }       /* pp[jk] is the total number of transitions starting from state jk and any ending status until this age */
                   4598:       
                   4599:        for(jk=1,pos=0, pospropta=0.; jk <=nlstate ; jk++){
                   4600:          pos += pp[jk]; /* pos is the total number of transitions until this age */
                   4601:          posprop[jk] += prop[jk][iage]; /* prop is the number of transitions from a live state
                   4602:                                            from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4603:          pospropta += prop[jk][iage]; /* prop is the number of transitions from a live state
1.240     brouard  4604:                                          from jk at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4605:        }
1.251     brouard  4606:        for(jk=1; jk <=nlstate ; jk++){
1.240     brouard  4607:          if(pos>=1.e-5){
1.251     brouard  4608:            if(first==1)
                   4609:              printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4610:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
                   4611:          }else{
                   4612:            if(first==1)
                   4613:              printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4614:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
                   4615:          }
                   4616:          if( iage <= iagemax){
                   4617:            if(pos>=1.e-5){
                   4618:              fprintf(ficresp," %d %.5f %.0f %.0f",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4619:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[jk][iage]/pospropta, prop[jk][iage],pospropta);
                   4620:              /*probs[iage][jk][j1]= pp[jk]/pos;*/
                   4621:              /*printf("\niage=%d jk=%d j1=%d %.5f %.0f %.0f %f",iage,jk,j1,pp[jk]/pos, pp[jk],pos,probs[iage][jk][j1]);*/
                   4622:            }
                   4623:            else{
                   4624:              fprintf(ficresp," %d NaNq %.0f %.0f",iage,prop[jk][iage],pospropta);
                   4625:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[jk][iage],pospropta);
                   4626:            }
1.240     brouard  4627:          }
1.251     brouard  4628:          pospropt[jk] +=posprop[jk];
                   4629:        } /* end loop jk */
                   4630:        /* pospropt=0.; */
                   4631:        for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4632:          for(m=-1; m <=nlstate+ndeath; m++){
                   4633:            if(freq[jk][m][iage] !=0 ) { /* minimizing output */
                   4634:              if(first==1){
                   4635:                printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4636:              }
1.253     brouard  4637:              /* printf(" %d%d=%.0f",jk,m,freq[jk][m][iage]); */
1.251     brouard  4638:              fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iage]);
                   4639:            }
                   4640:            if(jk!=0 && m!=0)
                   4641:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[jk][m][iage]);
1.240     brouard  4642:          }
1.251     brouard  4643:        } /* end loop jk */
                   4644:        posproptt=0.; 
                   4645:        for(jk=1; jk <=nlstate; jk++){
                   4646:          posproptt += pospropt[jk];
                   4647:        }
                   4648:        fprintf(ficresphtmfr,"</tr>\n ");
                   4649:        if(iage <= iagemax){
                   4650:          fprintf(ficresp,"\n");
                   4651:          fprintf(ficresphtm,"</tr>\n");
1.240     brouard  4652:        }
1.251     brouard  4653:        if(first==1)
                   4654:          printf("Others in log...\n");
                   4655:        fprintf(ficlog,"\n");
                   4656:       } /* end loop age iage */
                   4657:       fprintf(ficresphtm,"<tr><th>Tot</th>");
                   4658:       for(jk=1; jk <=nlstate ; jk++){
                   4659:        if(posproptt < 1.e-5){
                   4660:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[jk],posproptt); 
                   4661:        }else{
                   4662:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[jk]/posproptt,pospropt[jk],posproptt);  
1.240     brouard  4663:        }
1.226     brouard  4664:       }
1.251     brouard  4665:       fprintf(ficresphtm,"</tr>\n");
                   4666:       fprintf(ficresphtm,"</table>\n");
                   4667:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4668:       if(posproptt < 1.e-5){
1.251     brouard  4669:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4670:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4671:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4672:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4673:        invalidvarcomb[j1]=1;
1.226     brouard  4674:       }else{
1.251     brouard  4675:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4676:        invalidvarcomb[j1]=0;
1.226     brouard  4677:       }
1.251     brouard  4678:       fprintf(ficresphtmfr,"</table>\n");
                   4679:       fprintf(ficlog,"\n");
                   4680:       if(j!=0){
                   4681:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
                   4682:        for(i=1,jk=1; i <=nlstate; i++){
                   4683:          for(k=1; k <=(nlstate+ndeath); k++){
                   4684:            if (k != i) {
                   4685:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting jk */
1.253     brouard  4686:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4687:                  if(j1==1){ /* All dummy covariates to zero */
                   4688:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4689:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4690:                    printf("%d%d ",i,k);
                   4691:                    fprintf(ficlog,"%d%d ",i,k);
                   4692:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4693:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4694:                    pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4695:                  }
1.253     brouard  4696:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4697:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4698:                    x[iage]= (double)iage;
                   4699:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
                   4700:                    /* printf("i=%d, k=%d, jk=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,jk,j1,jj, iage, y[iage]); */
                   4701:                  }
                   4702:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
                   4703:                  pstart[jk]=b;
                   4704:                  pstart[jk-1]=a;
1.252     brouard  4705:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4706:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4707:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.251     brouard  4708:                  pstart[jk]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4709:                  printf("%d%d ",i,k);
                   4710:                  fprintf(ficlog,"%d%d ",i,k);
1.251     brouard  4711:                  printf("jk=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",jk,i,k,jk,p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
                   4712:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4713:                  ;
                   4714:                }
                   4715:                /* printf("%12.7f )", param[i][jj][k]); */
                   4716:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4717:                jk++; 
                   4718:              } /* end jj */
                   4719:            } /* end k!= i */
                   4720:          } /* end k */
                   4721:        } /* end i, jk */
                   4722:       } /* end j !=0 */
                   4723:     } /* end selected combination of covariate j1 */
                   4724:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4725:       printf("#Freqsummary: Starting values for the constants:\n");
                   4726:       fprintf(ficlog,"\n");
                   4727:       for(i=1,jk=1; i <=nlstate; i++){
                   4728:        for(k=1; k <=(nlstate+ndeath); k++){
                   4729:          if (k != i) {
                   4730:            printf("%d%d ",i,k);
                   4731:            fprintf(ficlog,"%d%d ",i,k);
                   4732:            for(jj=1; jj <=ncovmodel; jj++){
1.253     brouard  4733:              pstart[jk]=p[jk]; /* Setting pstart to p values by default */
                   4734:              if(jj==1){ /* Age has to be done */
                   4735:                pstart[jk]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4736:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4737:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[jk],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4738:              }
                   4739:              /* printf("%12.7f )", param[i][jj][k]); */
                   4740:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
                   4741:              jk++; 
1.250     brouard  4742:            }
1.251     brouard  4743:            printf("\n");
                   4744:            fprintf(ficlog,"\n");
1.250     brouard  4745:          }
                   4746:        }
                   4747:       }
1.251     brouard  4748:       printf("#Freqsummary\n");
                   4749:       fprintf(ficlog,"\n");
                   4750:       for(jk=-1; jk <=nlstate+ndeath; jk++){
                   4751:        for(m=-1; m <=nlstate+ndeath; m++){
                   4752:          /* param[i]|j][k]= freq[jk][m][iagemax+3] */
1.250     brouard  4753:          printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
                   4754:          fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]);
1.251     brouard  4755:          /* if(freq[jk][m][iage] !=0 ) { /\* minimizing output *\/ */
                   4756:          /*   printf(" %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4757:          /*   fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][iagemax+3]); */
                   4758:          /* } */
                   4759:        }
                   4760:       } /* end loop jk */
                   4761:       
                   4762:       printf("\n");
                   4763:       fprintf(ficlog,"\n");
                   4764:     } /* end j=0 */
1.249     brouard  4765:   } /* end j */
1.252     brouard  4766: 
1.253     brouard  4767:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4768:     for(i=1, jk=1; i <=nlstate; i++){
                   4769:       for(j=1; j <=nlstate+ndeath; j++){
                   4770:        if(j!=i){
                   4771:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4772:          printf("%1d%1d",i,j);
                   4773:          fprintf(ficparo,"%1d%1d",i,j);
                   4774:          for(k=1; k<=ncovmodel;k++){
                   4775:            /*    printf(" %lf",param[i][j][k]); */
                   4776:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4777:            p[jk]=pstart[jk];
                   4778:            printf(" %f ",pstart[jk]);
                   4779:            fprintf(ficparo," %f ",pstart[jk]);
                   4780:            jk++;
                   4781:          }
                   4782:          printf("\n");
                   4783:          fprintf(ficparo,"\n");
                   4784:        }
                   4785:       }
                   4786:     }
                   4787:   } /* end mle=-2 */
1.226     brouard  4788:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4789:   
1.226     brouard  4790:   fclose(ficresp);
                   4791:   fclose(ficresphtm);
                   4792:   fclose(ficresphtmfr);
                   4793:   free_vector(meanq,1,nqfveff);
                   4794:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4795:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4796:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4797:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4798:   free_vector(pospropt,1,nlstate);
                   4799:   free_vector(posprop,1,nlstate);
1.251     brouard  4800:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4801:   free_vector(pp,1,nlstate);
                   4802:   /* End of freqsummary */
                   4803: }
1.126     brouard  4804: 
                   4805: /************ Prevalence ********************/
1.227     brouard  4806: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4807: {  
                   4808:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4809:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4810:      We still use firstpass and lastpass as another selection.
                   4811:   */
1.126     brouard  4812:  
1.227     brouard  4813:   int i, m, jk, j1, bool, z1,j, iv;
                   4814:   int mi; /* Effective wave */
                   4815:   int iage;
                   4816:   double agebegin, ageend;
                   4817: 
                   4818:   double **prop;
                   4819:   double posprop; 
                   4820:   double  y2; /* in fractional years */
                   4821:   int iagemin, iagemax;
                   4822:   int first; /** to stop verbosity which is redirected to log file */
                   4823: 
                   4824:   iagemin= (int) agemin;
                   4825:   iagemax= (int) agemax;
                   4826:   /*pp=vector(1,nlstate);*/
1.251     brouard  4827:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4828:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4829:   j1=0;
1.222     brouard  4830:   
1.227     brouard  4831:   /*j=cptcoveff;*/
                   4832:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4833:   
1.227     brouard  4834:   first=1;
                   4835:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4836:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4837:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4838:        prop[i][iage]=0.0;
                   4839:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4840:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4841:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4842:     
                   4843:     for (i=1; i<=imx; i++) { /* Each individual */
                   4844:       bool=1;
                   4845:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4846:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4847:        m=mw[mi][i];
                   4848:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4849:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4850:        for (z1=1; z1<=cptcoveff; z1++){
                   4851:          if( Fixed[Tmodelind[z1]]==1){
                   4852:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4853:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4854:              bool=0;
                   4855:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4856:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4857:              bool=0;
                   4858:            }
                   4859:        }
                   4860:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4861:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4862:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4863:          if(m >=firstpass && m <=lastpass){
                   4864:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4865:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4866:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4867:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4868:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4869:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4870:                exit(1);
                   4871:              }
                   4872:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   4873:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   4874:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   4875:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   4876:              } /* end valid statuses */ 
                   4877:            } /* end selection of dates */
                   4878:          } /* end selection of waves */
                   4879:        } /* end bool */
                   4880:       } /* end wave */
                   4881:     } /* end individual */
                   4882:     for(i=iagemin; i <= iagemax+3; i++){  
                   4883:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   4884:        posprop += prop[jk][i]; 
                   4885:       } 
                   4886:       
                   4887:       for(jk=1; jk <=nlstate ; jk++){      
                   4888:        if( i <=  iagemax){ 
                   4889:          if(posprop>=1.e-5){ 
                   4890:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   4891:          } else{
                   4892:            if(first==1){
                   4893:              first=0;
                   4894:              printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,j1,probs[i][jk][j1]);
                   4895:            }
                   4896:          }
                   4897:        } 
                   4898:       }/* end jk */ 
                   4899:     }/* end i */ 
1.222     brouard  4900:      /*} *//* end i1 */
1.227     brouard  4901:   } /* end j1 */
1.222     brouard  4902:   
1.227     brouard  4903:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   4904:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  4905:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  4906: }  /* End of prevalence */
1.126     brouard  4907: 
                   4908: /************* Waves Concatenation ***************/
                   4909: 
                   4910: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   4911: {
                   4912:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   4913:      Death is a valid wave (if date is known).
                   4914:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   4915:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   4916:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  4917:   */
1.126     brouard  4918: 
1.224     brouard  4919:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  4920:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   4921:      double sum=0., jmean=0.;*/
1.224     brouard  4922:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  4923:   int j, k=0,jk, ju, jl;
                   4924:   double sum=0.;
                   4925:   first=0;
1.214     brouard  4926:   firstwo=0;
1.217     brouard  4927:   firsthree=0;
1.218     brouard  4928:   firstfour=0;
1.164     brouard  4929:   jmin=100000;
1.126     brouard  4930:   jmax=-1;
                   4931:   jmean=0.;
1.224     brouard  4932: 
                   4933: /* Treating live states */
1.214     brouard  4934:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  4935:     mi=0;  /* First valid wave */
1.227     brouard  4936:     mli=0; /* Last valid wave */
1.126     brouard  4937:     m=firstpass;
1.214     brouard  4938:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  4939:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   4940:        mli=m-1;/* mw[++mi][i]=m-1; */
                   4941:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   4942:        mw[++mi][i]=m;
                   4943:        mli=m;
1.224     brouard  4944:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   4945:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  4946:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  4947:       }
1.227     brouard  4948:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  4949: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  4950:        break;
1.224     brouard  4951: #else
1.227     brouard  4952:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   4953:          if(firsthree == 0){
1.262     brouard  4954:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  4955:            firsthree=1;
                   4956:          }
1.262     brouard  4957:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  4958:          mw[++mi][i]=m;
                   4959:          mli=m;
                   4960:        }
                   4961:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   4962:          nbwarn++;
                   4963:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   4964:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4965:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   4966:          }
                   4967:          break;
                   4968:        }
                   4969:        break;
1.224     brouard  4970: #endif
1.227     brouard  4971:       }/* End m >= lastpass */
1.126     brouard  4972:     }/* end while */
1.224     brouard  4973: 
1.227     brouard  4974:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  4975:     /* After last pass */
1.224     brouard  4976: /* Treating death states */
1.214     brouard  4977:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  4978:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   4979:       /* } */
1.126     brouard  4980:       mi++;    /* Death is another wave */
                   4981:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  4982:       /* Only death is a correct wave */
1.126     brouard  4983:       mw[mi][i]=m;
1.257     brouard  4984:     } /* else not in a death state */
1.224     brouard  4985: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  4986:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  4987:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  4988:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   4989:          nbwarn++;
                   4990:          if(firstfiv==0){
                   4991:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4992:            firstfiv=1;
                   4993:          }else{
                   4994:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   4995:          }
                   4996:        }else{ /* Death occured afer last wave potential bias */
                   4997:          nberr++;
                   4998:          if(firstwo==0){
1.257     brouard  4999:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5000:            firstwo=1;
                   5001:          }
1.257     brouard  5002:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5003:        }
1.257     brouard  5004:       }else{ /* if date of interview is unknown */
1.227     brouard  5005:        /* death is known but not confirmed by death status at any wave */
                   5006:        if(firstfour==0){
                   5007:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5008:          firstfour=1;
                   5009:        }
                   5010:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5011:       }
1.224     brouard  5012:     } /* end if date of death is known */
                   5013: #endif
                   5014:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5015:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5016:     if(mi==0){
                   5017:       nbwarn++;
                   5018:       if(first==0){
1.227     brouard  5019:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5020:        first=1;
1.126     brouard  5021:       }
                   5022:       if(first==1){
1.227     brouard  5023:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5024:       }
                   5025:     } /* end mi==0 */
                   5026:   } /* End individuals */
1.214     brouard  5027:   /* wav and mw are no more changed */
1.223     brouard  5028:        
1.214     brouard  5029:   
1.126     brouard  5030:   for(i=1; i<=imx; i++){
                   5031:     for(mi=1; mi<wav[i];mi++){
                   5032:       if (stepm <=0)
1.227     brouard  5033:        dh[mi][i]=1;
1.126     brouard  5034:       else{
1.260     brouard  5035:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5036:          if (agedc[i] < 2*AGESUP) {
                   5037:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5038:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5039:            else if(j<0){
                   5040:              nberr++;
                   5041:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5042:              j=1; /* Temporary Dangerous patch */
                   5043:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5044:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5045:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5046:            }
                   5047:            k=k+1;
                   5048:            if (j >= jmax){
                   5049:              jmax=j;
                   5050:              ijmax=i;
                   5051:            }
                   5052:            if (j <= jmin){
                   5053:              jmin=j;
                   5054:              ijmin=i;
                   5055:            }
                   5056:            sum=sum+j;
                   5057:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5058:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5059:          }
                   5060:        }
                   5061:        else{
                   5062:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5063: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5064:                                        
1.227     brouard  5065:          k=k+1;
                   5066:          if (j >= jmax) {
                   5067:            jmax=j;
                   5068:            ijmax=i;
                   5069:          }
                   5070:          else if (j <= jmin){
                   5071:            jmin=j;
                   5072:            ijmin=i;
                   5073:          }
                   5074:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5075:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5076:          if(j<0){
                   5077:            nberr++;
                   5078:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5079:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5080:          }
                   5081:          sum=sum+j;
                   5082:        }
                   5083:        jk= j/stepm;
                   5084:        jl= j -jk*stepm;
                   5085:        ju= j -(jk+1)*stepm;
                   5086:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5087:          if(jl==0){
                   5088:            dh[mi][i]=jk;
                   5089:            bh[mi][i]=0;
                   5090:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5091:                  * to avoid the price of an extra matrix product in likelihood */
                   5092:            dh[mi][i]=jk+1;
                   5093:            bh[mi][i]=ju;
                   5094:          }
                   5095:        }else{
                   5096:          if(jl <= -ju){
                   5097:            dh[mi][i]=jk;
                   5098:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5099:                                 * is higher than the multiple of stepm and negative otherwise.
                   5100:                                 */
                   5101:          }
                   5102:          else{
                   5103:            dh[mi][i]=jk+1;
                   5104:            bh[mi][i]=ju;
                   5105:          }
                   5106:          if(dh[mi][i]==0){
                   5107:            dh[mi][i]=1; /* At least one step */
                   5108:            bh[mi][i]=ju; /* At least one step */
                   5109:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5110:          }
                   5111:        } /* end if mle */
1.126     brouard  5112:       }
                   5113:     } /* end wave */
                   5114:   }
                   5115:   jmean=sum/k;
                   5116:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5117:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5118: }
1.126     brouard  5119: 
                   5120: /*********** Tricode ****************************/
1.220     brouard  5121:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5122:  {
                   5123:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5124:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5125:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5126:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5127:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5128:     */
1.130     brouard  5129: 
1.242     brouard  5130:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5131:    int modmaxcovj=0; /* Modality max of covariates j */
                   5132:    int cptcode=0; /* Modality max of covariates j */
                   5133:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5134: 
                   5135: 
1.242     brouard  5136:    /* cptcoveff=0;  */
                   5137:    /* *cptcov=0; */
1.126     brouard  5138:  
1.242     brouard  5139:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5140: 
1.242     brouard  5141:    /* Loop on covariates without age and products and no quantitative variable */
                   5142:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5143:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5144:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5145:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5146:        switch(Fixed[k]) {
                   5147:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5148:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5149:           ij=(int)(covar[Tvar[k]][i]);
                   5150:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5151:            * If product of Vn*Vm, still boolean *:
                   5152:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5153:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5154:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5155:              modality of the nth covariate of individual i. */
                   5156:           if (ij > modmaxcovj)
                   5157:             modmaxcovj=ij; 
                   5158:           else if (ij < modmincovj) 
                   5159:             modmincovj=ij; 
                   5160:           if ((ij < -1) && (ij > NCOVMAX)){
                   5161:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5162:             exit(1);
                   5163:           }else
                   5164:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5165:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5166:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5167:           /* getting the maximum value of the modality of the covariate
                   5168:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5169:              female ies 1, then modmaxcovj=1.
                   5170:           */
                   5171:         } /* end for loop on individuals i */
                   5172:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5173:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5174:         cptcode=modmaxcovj;
                   5175:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5176:         /*for (i=0; i<=cptcode; i++) {*/
                   5177:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5178:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5179:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5180:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5181:             if( j != -1){
                   5182:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5183:                                  covariate for which somebody answered excluding 
                   5184:                                  undefined. Usually 2: 0 and 1. */
                   5185:             }
                   5186:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5187:                                     covariate for which somebody answered including 
                   5188:                                     undefined. Usually 3: -1, 0 and 1. */
                   5189:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5190:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5191:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5192:                        
1.242     brouard  5193:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5194:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5195:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5196:         /* modmincovj=3; modmaxcovj = 7; */
                   5197:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5198:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5199:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5200:         /* nbcode[Tvar[j]][ij]=k; */
                   5201:         /* nbcode[Tvar[j]][1]=0; */
                   5202:         /* nbcode[Tvar[j]][2]=1; */
                   5203:         /* nbcode[Tvar[j]][3]=2; */
                   5204:         /* To be continued (not working yet). */
                   5205:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5206:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5207:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5208:             break;
                   5209:           }
                   5210:           ij++;
                   5211:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5212:           cptcode = ij; /* New max modality for covar j */
                   5213:         } /* end of loop on modality i=-1 to 1 or more */
                   5214:         break;
                   5215:        case 1: /* Testing on varying covariate, could be simple and
                   5216:                * should look at waves or product of fixed *
                   5217:                * varying. No time to test -1, assuming 0 and 1 only */
                   5218:         ij=0;
                   5219:         for(i=0; i<=1;i++){
                   5220:           nbcode[Tvar[k]][++ij]=i;
                   5221:         }
                   5222:         break;
                   5223:        default:
                   5224:         break;
                   5225:        } /* end switch */
                   5226:      } /* end dummy test */
                   5227:     
                   5228:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5229:      /*        /\*recode from 0 *\/ */
                   5230:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5231:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5232:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5233:      /*        } */
                   5234:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5235:      /*        if (ij > ncodemax[j]) { */
                   5236:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5237:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5238:      /*          break; */
                   5239:      /*        } */
                   5240:      /*   }  /\* end of loop on modality k *\/ */
                   5241:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5242:   
                   5243:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5244:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5245:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5246:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5247:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5248:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5249:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5250:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5251:   
                   5252:    ij=0;
                   5253:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5254:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5255:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5256:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5257:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5258:        /* If product not in single variable we don't print results */
                   5259:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5260:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5261:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5262:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5263:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5264:        if(Fixed[k]!=0)
                   5265:         anyvaryingduminmodel=1;
                   5266:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5267:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5268:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5269:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5270:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5271:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5272:      } 
                   5273:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5274:    /* ij--; */
                   5275:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5276:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5277:                * because they can be excluded from the model and real
                   5278:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5279:    for(j=ij+1; j<= cptcovt; j++){
                   5280:      Tvaraff[j]=0;
                   5281:      Tmodelind[j]=0;
                   5282:    }
                   5283:    for(j=ntveff+1; j<= cptcovt; j++){
                   5284:      TmodelInvind[j]=0;
                   5285:    }
                   5286:    /* To be sorted */
                   5287:    ;
                   5288:  }
1.126     brouard  5289: 
1.145     brouard  5290: 
1.126     brouard  5291: /*********** Health Expectancies ****************/
                   5292: 
1.235     brouard  5293:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5294: 
                   5295: {
                   5296:   /* Health expectancies, no variances */
1.164     brouard  5297:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5298:   int nhstepma, nstepma; /* Decreasing with age */
                   5299:   double age, agelim, hf;
                   5300:   double ***p3mat;
                   5301:   double eip;
                   5302: 
1.238     brouard  5303:   /* pstamp(ficreseij); */
1.126     brouard  5304:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5305:   fprintf(ficreseij,"# Age");
                   5306:   for(i=1; i<=nlstate;i++){
                   5307:     for(j=1; j<=nlstate;j++){
                   5308:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5309:     }
                   5310:     fprintf(ficreseij," e%1d. ",i);
                   5311:   }
                   5312:   fprintf(ficreseij,"\n");
                   5313: 
                   5314:   
                   5315:   if(estepm < stepm){
                   5316:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5317:   }
                   5318:   else  hstepm=estepm;   
                   5319:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5320:    * This is mainly to measure the difference between two models: for example
                   5321:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5322:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5323:    * progression in between and thus overestimating or underestimating according
                   5324:    * to the curvature of the survival function. If, for the same date, we 
                   5325:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5326:    * to compare the new estimate of Life expectancy with the same linear 
                   5327:    * hypothesis. A more precise result, taking into account a more precise
                   5328:    * curvature will be obtained if estepm is as small as stepm. */
                   5329: 
                   5330:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5331:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5332:      nhstepm is the number of hstepm from age to agelim 
                   5333:      nstepm is the number of stepm from age to agelin. 
                   5334:      Look at hpijx to understand the reason of that which relies in memory size
                   5335:      and note for a fixed period like estepm months */
                   5336:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5337:      survival function given by stepm (the optimization length). Unfortunately it
                   5338:      means that if the survival funtion is printed only each two years of age and if
                   5339:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5340:      results. So we changed our mind and took the option of the best precision.
                   5341:   */
                   5342:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5343: 
                   5344:   agelim=AGESUP;
                   5345:   /* If stepm=6 months */
                   5346:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5347:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5348:     
                   5349: /* nhstepm age range expressed in number of stepm */
                   5350:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5351:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5352:   /* if (stepm >= YEARM) hstepm=1;*/
                   5353:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5354:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5355: 
                   5356:   for (age=bage; age<=fage; age ++){ 
                   5357:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5358:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5359:     /* if (stepm >= YEARM) hstepm=1;*/
                   5360:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5361: 
                   5362:     /* If stepm=6 months */
                   5363:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5364:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5365:     
1.235     brouard  5366:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5367:     
                   5368:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5369:     
                   5370:     printf("%d|",(int)age);fflush(stdout);
                   5371:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5372:     
                   5373:     /* Computing expectancies */
                   5374:     for(i=1; i<=nlstate;i++)
                   5375:       for(j=1; j<=nlstate;j++)
                   5376:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5377:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5378:          
                   5379:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5380: 
                   5381:        }
                   5382: 
                   5383:     fprintf(ficreseij,"%3.0f",age );
                   5384:     for(i=1; i<=nlstate;i++){
                   5385:       eip=0;
                   5386:       for(j=1; j<=nlstate;j++){
                   5387:        eip +=eij[i][j][(int)age];
                   5388:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5389:       }
                   5390:       fprintf(ficreseij,"%9.4f", eip );
                   5391:     }
                   5392:     fprintf(ficreseij,"\n");
                   5393:     
                   5394:   }
                   5395:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5396:   printf("\n");
                   5397:   fprintf(ficlog,"\n");
                   5398:   
                   5399: }
                   5400: 
1.235     brouard  5401:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5402: 
                   5403: {
                   5404:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5405:      to initial status i, ei. .
1.126     brouard  5406:   */
                   5407:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5408:   int nhstepma, nstepma; /* Decreasing with age */
                   5409:   double age, agelim, hf;
                   5410:   double ***p3matp, ***p3matm, ***varhe;
                   5411:   double **dnewm,**doldm;
                   5412:   double *xp, *xm;
                   5413:   double **gp, **gm;
                   5414:   double ***gradg, ***trgradg;
                   5415:   int theta;
                   5416: 
                   5417:   double eip, vip;
                   5418: 
                   5419:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5420:   xp=vector(1,npar);
                   5421:   xm=vector(1,npar);
                   5422:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5423:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5424:   
                   5425:   pstamp(ficresstdeij);
                   5426:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5427:   fprintf(ficresstdeij,"# Age");
                   5428:   for(i=1; i<=nlstate;i++){
                   5429:     for(j=1; j<=nlstate;j++)
                   5430:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5431:     fprintf(ficresstdeij," e%1d. ",i);
                   5432:   }
                   5433:   fprintf(ficresstdeij,"\n");
                   5434: 
                   5435:   pstamp(ficrescveij);
                   5436:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5437:   fprintf(ficrescveij,"# Age");
                   5438:   for(i=1; i<=nlstate;i++)
                   5439:     for(j=1; j<=nlstate;j++){
                   5440:       cptj= (j-1)*nlstate+i;
                   5441:       for(i2=1; i2<=nlstate;i2++)
                   5442:        for(j2=1; j2<=nlstate;j2++){
                   5443:          cptj2= (j2-1)*nlstate+i2;
                   5444:          if(cptj2 <= cptj)
                   5445:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5446:        }
                   5447:     }
                   5448:   fprintf(ficrescveij,"\n");
                   5449:   
                   5450:   if(estepm < stepm){
                   5451:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5452:   }
                   5453:   else  hstepm=estepm;   
                   5454:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5455:    * This is mainly to measure the difference between two models: for example
                   5456:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5457:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5458:    * progression in between and thus overestimating or underestimating according
                   5459:    * to the curvature of the survival function. If, for the same date, we 
                   5460:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5461:    * to compare the new estimate of Life expectancy with the same linear 
                   5462:    * hypothesis. A more precise result, taking into account a more precise
                   5463:    * curvature will be obtained if estepm is as small as stepm. */
                   5464: 
                   5465:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5466:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5467:      nhstepm is the number of hstepm from age to agelim 
                   5468:      nstepm is the number of stepm from age to agelin. 
                   5469:      Look at hpijx to understand the reason of that which relies in memory size
                   5470:      and note for a fixed period like estepm months */
                   5471:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5472:      survival function given by stepm (the optimization length). Unfortunately it
                   5473:      means that if the survival funtion is printed only each two years of age and if
                   5474:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5475:      results. So we changed our mind and took the option of the best precision.
                   5476:   */
                   5477:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5478: 
                   5479:   /* If stepm=6 months */
                   5480:   /* nhstepm age range expressed in number of stepm */
                   5481:   agelim=AGESUP;
                   5482:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5483:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5484:   /* if (stepm >= YEARM) hstepm=1;*/
                   5485:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5486:   
                   5487:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5488:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5489:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5490:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5491:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5492:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5493: 
                   5494:   for (age=bage; age<=fage; age ++){ 
                   5495:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5496:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5497:     /* if (stepm >= YEARM) hstepm=1;*/
                   5498:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5499:                
1.126     brouard  5500:     /* If stepm=6 months */
                   5501:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5502:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5503:     
                   5504:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5505:                
1.126     brouard  5506:     /* Computing  Variances of health expectancies */
                   5507:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5508:        decrease memory allocation */
                   5509:     for(theta=1; theta <=npar; theta++){
                   5510:       for(i=1; i<=npar; i++){ 
1.222     brouard  5511:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5512:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5513:       }
1.235     brouard  5514:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5515:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5516:                        
1.126     brouard  5517:       for(j=1; j<= nlstate; j++){
1.222     brouard  5518:        for(i=1; i<=nlstate; i++){
                   5519:          for(h=0; h<=nhstepm-1; h++){
                   5520:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5521:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5522:          }
                   5523:        }
1.126     brouard  5524:       }
1.218     brouard  5525:                        
1.126     brouard  5526:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5527:        for(h=0; h<=nhstepm-1; h++){
                   5528:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5529:        }
1.126     brouard  5530:     }/* End theta */
                   5531:     
                   5532:     
                   5533:     for(h=0; h<=nhstepm-1; h++)
                   5534:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5535:        for(theta=1; theta <=npar; theta++)
                   5536:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5537:     
1.218     brouard  5538:                
1.222     brouard  5539:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5540:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5541:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5542:                
1.222     brouard  5543:     printf("%d|",(int)age);fflush(stdout);
                   5544:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5545:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5546:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5547:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5548:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5549:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5550:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5551:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5552:       }
                   5553:     }
1.218     brouard  5554:                
1.126     brouard  5555:     /* Computing expectancies */
1.235     brouard  5556:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5557:     for(i=1; i<=nlstate;i++)
                   5558:       for(j=1; j<=nlstate;j++)
1.222     brouard  5559:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5560:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5561:                                        
1.222     brouard  5562:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5563:                                        
1.222     brouard  5564:        }
1.218     brouard  5565:                
1.126     brouard  5566:     fprintf(ficresstdeij,"%3.0f",age );
                   5567:     for(i=1; i<=nlstate;i++){
                   5568:       eip=0.;
                   5569:       vip=0.;
                   5570:       for(j=1; j<=nlstate;j++){
1.222     brouard  5571:        eip += eij[i][j][(int)age];
                   5572:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5573:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5574:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5575:       }
                   5576:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5577:     }
                   5578:     fprintf(ficresstdeij,"\n");
1.218     brouard  5579:                
1.126     brouard  5580:     fprintf(ficrescveij,"%3.0f",age );
                   5581:     for(i=1; i<=nlstate;i++)
                   5582:       for(j=1; j<=nlstate;j++){
1.222     brouard  5583:        cptj= (j-1)*nlstate+i;
                   5584:        for(i2=1; i2<=nlstate;i2++)
                   5585:          for(j2=1; j2<=nlstate;j2++){
                   5586:            cptj2= (j2-1)*nlstate+i2;
                   5587:            if(cptj2 <= cptj)
                   5588:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5589:          }
1.126     brouard  5590:       }
                   5591:     fprintf(ficrescveij,"\n");
1.218     brouard  5592:                
1.126     brouard  5593:   }
                   5594:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5595:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5596:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5597:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5598:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5599:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5600:   printf("\n");
                   5601:   fprintf(ficlog,"\n");
1.218     brouard  5602:        
1.126     brouard  5603:   free_vector(xm,1,npar);
                   5604:   free_vector(xp,1,npar);
                   5605:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5606:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5607:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5608: }
1.218     brouard  5609:  
1.126     brouard  5610: /************ Variance ******************/
1.235     brouard  5611:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5612:  {
                   5613:    /* Variance of health expectancies */
                   5614:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5615:    /* double **newm;*/
                   5616:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5617:   
                   5618:    /* int movingaverage(); */
                   5619:    double **dnewm,**doldm;
                   5620:    double **dnewmp,**doldmp;
                   5621:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5622:    int k;
                   5623:    double *xp;
                   5624:    double **gp, **gm;  /* for var eij */
                   5625:    double ***gradg, ***trgradg; /*for var eij */
                   5626:    double **gradgp, **trgradgp; /* for var p point j */
                   5627:    double *gpp, *gmp; /* for var p point j */
                   5628:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5629:    double ***p3mat;
                   5630:    double age,agelim, hf;
                   5631:    /* double ***mobaverage; */
                   5632:    int theta;
                   5633:    char digit[4];
                   5634:    char digitp[25];
                   5635: 
                   5636:    char fileresprobmorprev[FILENAMELENGTH];
                   5637: 
                   5638:    if(popbased==1){
                   5639:      if(mobilav!=0)
                   5640:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5641:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5642:    }
                   5643:    else 
                   5644:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5645: 
1.218     brouard  5646:    /* if (mobilav!=0) { */
                   5647:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5648:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5649:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5650:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5651:    /*   } */
                   5652:    /* } */
                   5653: 
                   5654:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5655:    sprintf(digit,"%-d",ij);
                   5656:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5657:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5658:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5659:    strcat(fileresprobmorprev,fileresu);
                   5660:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5661:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5662:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5663:    }
                   5664:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5665:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5666:    pstamp(ficresprobmorprev);
                   5667:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5668:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5669:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5670:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5671:    }
                   5672:    for(j=1;j<=cptcoveff;j++) 
                   5673:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5674:    fprintf(ficresprobmorprev,"\n");
                   5675: 
1.218     brouard  5676:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5677:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5678:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5679:      for(i=1; i<=nlstate;i++)
                   5680:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5681:    }  
                   5682:    fprintf(ficresprobmorprev,"\n");
                   5683:   
                   5684:    fprintf(ficgp,"\n# Routine varevsij");
                   5685:    fprintf(ficgp,"\nunset title \n");
                   5686:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5687:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5688:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5689:    /*   } */
                   5690:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5691:    pstamp(ficresvij);
                   5692:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5693:    if(popbased==1)
                   5694:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5695:    else
                   5696:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5697:    fprintf(ficresvij,"# Age");
                   5698:    for(i=1; i<=nlstate;i++)
                   5699:      for(j=1; j<=nlstate;j++)
                   5700:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5701:    fprintf(ficresvij,"\n");
                   5702: 
                   5703:    xp=vector(1,npar);
                   5704:    dnewm=matrix(1,nlstate,1,npar);
                   5705:    doldm=matrix(1,nlstate,1,nlstate);
                   5706:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5707:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5708: 
                   5709:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5710:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5711:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5712:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5713:   
1.218     brouard  5714:    if(estepm < stepm){
                   5715:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5716:    }
                   5717:    else  hstepm=estepm;   
                   5718:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5719:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5720:       nhstepm is the number of hstepm from age to agelim 
                   5721:       nstepm is the number of stepm from age to agelim. 
                   5722:       Look at function hpijx to understand why because of memory size limitations, 
                   5723:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5724:       survival function given by stepm (the optimization length). Unfortunately it
                   5725:       means that if the survival funtion is printed every two years of age and if
                   5726:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5727:       results. So we changed our mind and took the option of the best precision.
                   5728:    */
                   5729:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5730:    agelim = AGESUP;
                   5731:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5732:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5733:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5734:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5735:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5736:      gp=matrix(0,nhstepm,1,nlstate);
                   5737:      gm=matrix(0,nhstepm,1,nlstate);
                   5738:                
                   5739:                
                   5740:      for(theta=1; theta <=npar; theta++){
                   5741:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5742:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5743:        }
                   5744:                        
1.242     brouard  5745:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5746:                        
                   5747:        if (popbased==1) {
                   5748:         if(mobilav ==0){
                   5749:           for(i=1; i<=nlstate;i++)
                   5750:             prlim[i][i]=probs[(int)age][i][ij];
                   5751:         }else{ /* mobilav */ 
                   5752:           for(i=1; i<=nlstate;i++)
                   5753:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5754:         }
                   5755:        }
                   5756:                        
1.235     brouard  5757:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5758:        for(j=1; j<= nlstate; j++){
                   5759:         for(h=0; h<=nhstepm; h++){
                   5760:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5761:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5762:         }
                   5763:        }
                   5764:        /* Next for computing probability of death (h=1 means
                   5765:          computed over hstepm matrices product = hstepm*stepm months) 
                   5766:          as a weighted average of prlim.
                   5767:        */
                   5768:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5769:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5770:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5771:        }    
                   5772:        /* end probability of death */
                   5773:                        
                   5774:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5775:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5776:                        
1.242     brouard  5777:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5778:                        
                   5779:        if (popbased==1) {
                   5780:         if(mobilav ==0){
                   5781:           for(i=1; i<=nlstate;i++)
                   5782:             prlim[i][i]=probs[(int)age][i][ij];
                   5783:         }else{ /* mobilav */ 
                   5784:           for(i=1; i<=nlstate;i++)
                   5785:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5786:         }
                   5787:        }
                   5788:                        
1.235     brouard  5789:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5790:                        
                   5791:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5792:         for(h=0; h<=nhstepm; h++){
                   5793:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5794:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5795:         }
                   5796:        }
                   5797:        /* This for computing probability of death (h=1 means
                   5798:          computed over hstepm matrices product = hstepm*stepm months) 
                   5799:          as a weighted average of prlim.
                   5800:        */
                   5801:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5802:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5803:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5804:        }    
                   5805:        /* end probability of death */
                   5806:                        
                   5807:        for(j=1; j<= nlstate; j++) /* vareij */
                   5808:         for(h=0; h<=nhstepm; h++){
                   5809:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5810:         }
                   5811:                        
                   5812:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5813:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5814:        }
                   5815:                        
                   5816:      } /* End theta */
                   5817:                
                   5818:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5819:                
                   5820:      for(h=0; h<=nhstepm; h++) /* veij */
                   5821:        for(j=1; j<=nlstate;j++)
                   5822:         for(theta=1; theta <=npar; theta++)
                   5823:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5824:                
                   5825:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5826:        for(theta=1; theta <=npar; theta++)
                   5827:         trgradgp[j][theta]=gradgp[theta][j];
                   5828:                
                   5829:                
                   5830:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5831:      for(i=1;i<=nlstate;i++)
                   5832:        for(j=1;j<=nlstate;j++)
                   5833:         vareij[i][j][(int)age] =0.;
                   5834:                
                   5835:      for(h=0;h<=nhstepm;h++){
                   5836:        for(k=0;k<=nhstepm;k++){
                   5837:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5838:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5839:         for(i=1;i<=nlstate;i++)
                   5840:           for(j=1;j<=nlstate;j++)
                   5841:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5842:        }
                   5843:      }
                   5844:                
                   5845:      /* pptj */
                   5846:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5847:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5848:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5849:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5850:         varppt[j][i]=doldmp[j][i];
                   5851:      /* end ppptj */
                   5852:      /*  x centered again */
                   5853:                
1.242     brouard  5854:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5855:                
                   5856:      if (popbased==1) {
                   5857:        if(mobilav ==0){
                   5858:         for(i=1; i<=nlstate;i++)
                   5859:           prlim[i][i]=probs[(int)age][i][ij];
                   5860:        }else{ /* mobilav */ 
                   5861:         for(i=1; i<=nlstate;i++)
                   5862:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5863:        }
                   5864:      }
                   5865:                
                   5866:      /* This for computing probability of death (h=1 means
                   5867:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   5868:        as a weighted average of prlim.
                   5869:      */
1.235     brouard  5870:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  5871:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5872:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   5873:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   5874:      }    
                   5875:      /* end probability of death */
                   5876:                
                   5877:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   5878:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5879:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   5880:        for(i=1; i<=nlstate;i++){
                   5881:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   5882:        }
                   5883:      } 
                   5884:      fprintf(ficresprobmorprev,"\n");
                   5885:                
                   5886:      fprintf(ficresvij,"%.0f ",age );
                   5887:      for(i=1; i<=nlstate;i++)
                   5888:        for(j=1; j<=nlstate;j++){
                   5889:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   5890:        }
                   5891:      fprintf(ficresvij,"\n");
                   5892:      free_matrix(gp,0,nhstepm,1,nlstate);
                   5893:      free_matrix(gm,0,nhstepm,1,nlstate);
                   5894:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   5895:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   5896:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5897:    } /* End age */
                   5898:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   5899:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   5900:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   5901:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   5902:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   5903:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   5904:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   5905:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   5906:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5907:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   5908:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5909:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   5910:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   5911:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   5912:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   5913:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   5914:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   5915:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  5916:     */
1.218     brouard  5917:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   5918:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  5919: 
1.218     brouard  5920:    free_vector(xp,1,npar);
                   5921:    free_matrix(doldm,1,nlstate,1,nlstate);
                   5922:    free_matrix(dnewm,1,nlstate,1,npar);
                   5923:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5924:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   5925:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5926:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5927:    fclose(ficresprobmorprev);
                   5928:    fflush(ficgp);
                   5929:    fflush(fichtm); 
                   5930:  }  /* end varevsij */
1.126     brouard  5931: 
                   5932: /************ Variance of prevlim ******************/
1.235     brouard  5933:  void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  5934: {
1.205     brouard  5935:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  5936:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  5937: 
1.126     brouard  5938:   double **dnewm,**doldm;
                   5939:   int i, j, nhstepm, hstepm;
                   5940:   double *xp;
                   5941:   double *gp, *gm;
                   5942:   double **gradg, **trgradg;
1.208     brouard  5943:   double **mgm, **mgp;
1.126     brouard  5944:   double age,agelim;
                   5945:   int theta;
                   5946:   
                   5947:   pstamp(ficresvpl);
                   5948:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  5949:   fprintf(ficresvpl,"# Age ");
                   5950:   if(nresult >=1)
                   5951:     fprintf(ficresvpl," Result# ");
1.126     brouard  5952:   for(i=1; i<=nlstate;i++)
                   5953:       fprintf(ficresvpl," %1d-%1d",i,i);
                   5954:   fprintf(ficresvpl,"\n");
                   5955: 
                   5956:   xp=vector(1,npar);
                   5957:   dnewm=matrix(1,nlstate,1,npar);
                   5958:   doldm=matrix(1,nlstate,1,nlstate);
                   5959:   
                   5960:   hstepm=1*YEARM; /* Every year of age */
                   5961:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   5962:   agelim = AGESUP;
                   5963:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5964:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5965:     if (stepm >= YEARM) hstepm=1;
                   5966:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   5967:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  5968:     mgp=matrix(1,npar,1,nlstate);
                   5969:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  5970:     gp=vector(1,nlstate);
                   5971:     gm=vector(1,nlstate);
                   5972: 
                   5973:     for(theta=1; theta <=npar; theta++){
                   5974:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   5975:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5976:       }
1.209     brouard  5977:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5978:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5979:       else
1.235     brouard  5980:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5981:       for(i=1;i<=nlstate;i++){
1.126     brouard  5982:        gp[i] = prlim[i][i];
1.208     brouard  5983:        mgp[theta][i] = prlim[i][i];
                   5984:       }
1.126     brouard  5985:       for(i=1; i<=npar; i++) /* Computes gradient */
                   5986:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  5987:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  5988:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  5989:       else
1.235     brouard  5990:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  5991:       for(i=1;i<=nlstate;i++){
1.126     brouard  5992:        gm[i] = prlim[i][i];
1.208     brouard  5993:        mgm[theta][i] = prlim[i][i];
                   5994:       }
1.126     brouard  5995:       for(i=1;i<=nlstate;i++)
                   5996:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  5997:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  5998:     } /* End theta */
                   5999: 
                   6000:     trgradg =matrix(1,nlstate,1,npar);
                   6001: 
                   6002:     for(j=1; j<=nlstate;j++)
                   6003:       for(theta=1; theta <=npar; theta++)
                   6004:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6005:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6006:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6007:     /*   for(j=1; j<=nlstate;j++){ */
                   6008:     /*         printf(" %d ",j); */
                   6009:     /*         for(theta=1; theta <=npar; theta++) */
                   6010:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6011:     /*         printf("\n "); */
                   6012:     /*   } */
                   6013:     /* } */
                   6014:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6015:     /*   printf("\n gradg %d ",(int)age); */
                   6016:     /*   for(j=1; j<=nlstate;j++){ */
                   6017:     /*         printf("%d ",j); */
                   6018:     /*         for(theta=1; theta <=npar; theta++) */
                   6019:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6020:     /*         printf("\n "); */
                   6021:     /*   } */
                   6022:     /* } */
1.126     brouard  6023: 
                   6024:     for(i=1;i<=nlstate;i++)
                   6025:       varpl[i][(int)age] =0.;
1.209     brouard  6026:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.205     brouard  6027:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6028:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
                   6029:     }else{
1.126     brouard  6030:     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6031:     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6032:     }
1.126     brouard  6033:     for(i=1;i<=nlstate;i++)
                   6034:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6035: 
                   6036:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6037:     if(nresult >=1)
                   6038:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6039:     for(i=1; i<=nlstate;i++)
                   6040:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6041:     fprintf(ficresvpl,"\n");
                   6042:     free_vector(gp,1,nlstate);
                   6043:     free_vector(gm,1,nlstate);
1.208     brouard  6044:     free_matrix(mgm,1,npar,1,nlstate);
                   6045:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6046:     free_matrix(gradg,1,npar,1,nlstate);
                   6047:     free_matrix(trgradg,1,nlstate,1,npar);
                   6048:   } /* End age */
                   6049: 
                   6050:   free_vector(xp,1,npar);
                   6051:   free_matrix(doldm,1,nlstate,1,npar);
                   6052:   free_matrix(dnewm,1,nlstate,1,nlstate);
                   6053: 
                   6054: }
                   6055: 
                   6056: /************ Variance of one-step probabilities  ******************/
                   6057: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6058:  {
                   6059:    int i, j=0,  k1, l1, tj;
                   6060:    int k2, l2, j1,  z1;
                   6061:    int k=0, l;
                   6062:    int first=1, first1, first2;
                   6063:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6064:    double **dnewm,**doldm;
                   6065:    double *xp;
                   6066:    double *gp, *gm;
                   6067:    double **gradg, **trgradg;
                   6068:    double **mu;
                   6069:    double age, cov[NCOVMAX+1];
                   6070:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6071:    int theta;
                   6072:    char fileresprob[FILENAMELENGTH];
                   6073:    char fileresprobcov[FILENAMELENGTH];
                   6074:    char fileresprobcor[FILENAMELENGTH];
                   6075:    double ***varpij;
                   6076: 
                   6077:    strcpy(fileresprob,"PROB_"); 
                   6078:    strcat(fileresprob,fileres);
                   6079:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6080:      printf("Problem with resultfile: %s\n", fileresprob);
                   6081:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6082:    }
                   6083:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6084:    strcat(fileresprobcov,fileresu);
                   6085:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6086:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6087:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6088:    }
                   6089:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6090:    strcat(fileresprobcor,fileresu);
                   6091:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6092:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6093:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6094:    }
                   6095:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6096:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6097:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6098:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6099:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6100:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6101:    pstamp(ficresprob);
                   6102:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6103:    fprintf(ficresprob,"# Age");
                   6104:    pstamp(ficresprobcov);
                   6105:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6106:    fprintf(ficresprobcov,"# Age");
                   6107:    pstamp(ficresprobcor);
                   6108:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6109:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6110: 
                   6111: 
1.222     brouard  6112:    for(i=1; i<=nlstate;i++)
                   6113:      for(j=1; j<=(nlstate+ndeath);j++){
                   6114:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6115:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6116:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6117:      }  
                   6118:    /* fprintf(ficresprob,"\n");
                   6119:       fprintf(ficresprobcov,"\n");
                   6120:       fprintf(ficresprobcor,"\n");
                   6121:    */
                   6122:    xp=vector(1,npar);
                   6123:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6124:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6125:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6126:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6127:    first=1;
                   6128:    fprintf(ficgp,"\n# Routine varprob");
                   6129:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6130:    fprintf(fichtm,"\n");
                   6131: 
                   6132:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
                   6133:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6134:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6135: and drawn. It helps understanding how is the covariance between two incidences.\
                   6136:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6137:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6138: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6139: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6140: standard deviations wide on each axis. <br>\
                   6141:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6142:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6143: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6144: 
1.222     brouard  6145:    cov[1]=1;
                   6146:    /* tj=cptcoveff; */
1.225     brouard  6147:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6148:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6149:    j1=0;
1.224     brouard  6150:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6151:      if  (cptcovn>0) {
                   6152:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6153:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6154:        fprintf(ficresprob, "**********\n#\n");
                   6155:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6156:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6157:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6158:                        
1.222     brouard  6159:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6160:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6161:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6162:                        
                   6163:                        
1.222     brouard  6164:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6165:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6166:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6167:                        
1.222     brouard  6168:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6169:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6170:        fprintf(ficresprobcor, "**********\n#");    
                   6171:        if(invalidvarcomb[j1]){
                   6172:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6173:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6174:         continue;
                   6175:        }
                   6176:      }
                   6177:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6178:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6179:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6180:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6181:      for (age=bage; age<=fage; age ++){ 
                   6182:        cov[2]=age;
                   6183:        if(nagesqr==1)
                   6184:         cov[3]= age*age;
                   6185:        for (k=1; k<=cptcovn;k++) {
                   6186:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6187:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6188:                                                                    * 1  1 1 1 1
                   6189:                                                                    * 2  2 1 1 1
                   6190:                                                                    * 3  1 2 1 1
                   6191:                                                                    */
                   6192:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6193:        }
                   6194:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6195:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6196:        for (k=1; k<=cptcovprod;k++)
                   6197:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6198:                        
                   6199:                        
1.222     brouard  6200:        for(theta=1; theta <=npar; theta++){
                   6201:         for(i=1; i<=npar; i++)
                   6202:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6203:                                
1.222     brouard  6204:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6205:                                
1.222     brouard  6206:         k=0;
                   6207:         for(i=1; i<= (nlstate); i++){
                   6208:           for(j=1; j<=(nlstate+ndeath);j++){
                   6209:             k=k+1;
                   6210:             gp[k]=pmmij[i][j];
                   6211:           }
                   6212:         }
1.220     brouard  6213:                                
1.222     brouard  6214:         for(i=1; i<=npar; i++)
                   6215:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6216:                                
1.222     brouard  6217:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6218:         k=0;
                   6219:         for(i=1; i<=(nlstate); i++){
                   6220:           for(j=1; j<=(nlstate+ndeath);j++){
                   6221:             k=k+1;
                   6222:             gm[k]=pmmij[i][j];
                   6223:           }
                   6224:         }
1.220     brouard  6225:                                
1.222     brouard  6226:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6227:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6228:        }
1.126     brouard  6229: 
1.222     brouard  6230:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6231:         for(theta=1; theta <=npar; theta++)
                   6232:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6233:                        
1.222     brouard  6234:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6235:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6236:                        
1.222     brouard  6237:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6238:                        
1.222     brouard  6239:        k=0;
                   6240:        for(i=1; i<=(nlstate); i++){
                   6241:         for(j=1; j<=(nlstate+ndeath);j++){
                   6242:           k=k+1;
                   6243:           mu[k][(int) age]=pmmij[i][j];
                   6244:         }
                   6245:        }
                   6246:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6247:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6248:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6249:                        
1.222     brouard  6250:        /*printf("\n%d ",(int)age);
                   6251:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6252:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6253:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6254:         }*/
1.220     brouard  6255:                        
1.222     brouard  6256:        fprintf(ficresprob,"\n%d ",(int)age);
                   6257:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6258:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6259:                        
1.222     brouard  6260:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6261:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6262:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6263:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6264:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6265:        }
                   6266:        i=0;
                   6267:        for (k=1; k<=(nlstate);k++){
                   6268:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6269:           i++;
                   6270:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6271:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6272:           for (j=1; j<=i;j++){
                   6273:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6274:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6275:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6276:           }
                   6277:         }
                   6278:        }/* end of loop for state */
                   6279:      } /* end of loop for age */
                   6280:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6281:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6282:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6283:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6284:     
                   6285:      /* Confidence intervalle of pij  */
                   6286:      /*
                   6287:        fprintf(ficgp,"\nunset parametric;unset label");
                   6288:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6289:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6290:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6291:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6292:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6293:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6294:      */
                   6295:                
                   6296:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6297:      first1=1;first2=2;
                   6298:      for (k2=1; k2<=(nlstate);k2++){
                   6299:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6300:         if(l2==k2) continue;
                   6301:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6302:         for (k1=1; k1<=(nlstate);k1++){
                   6303:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6304:             if(l1==k1) continue;
                   6305:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6306:             if(i<=j) continue;
                   6307:             for (age=bage; age<=fage; age ++){ 
                   6308:               if ((int)age %5==0){
                   6309:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6310:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6311:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6312:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6313:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6314:                 c12=cv12/sqrt(v1*v2);
                   6315:                 /* Computing eigen value of matrix of covariance */
                   6316:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6317:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6318:                 if ((lc2 <0) || (lc1 <0) ){
                   6319:                   if(first2==1){
                   6320:                     first1=0;
                   6321:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6322:                   }
                   6323:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6324:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6325:                   /* lc2=fabs(lc2); */
                   6326:                 }
1.220     brouard  6327:                                                                
1.222     brouard  6328:                 /* Eigen vectors */
                   6329:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6330:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6331:                 v21=(lc1-v1)/cv12*v11;
                   6332:                 v12=-v21;
                   6333:                 v22=v11;
                   6334:                 tnalp=v21/v11;
                   6335:                 if(first1==1){
                   6336:                   first1=0;
                   6337:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6338:                 }
                   6339:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6340:                 /*printf(fignu*/
                   6341:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6342:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6343:                 if(first==1){
                   6344:                   first=0;
                   6345:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6346:                   fprintf(ficgp,"\nset parametric;unset label");
                   6347:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6348:                   fprintf(ficgp,"\nset ter svg size 640, 480");
                   6349:                   fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6350:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6351: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6352:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6353:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6354:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6355:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6356:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6357:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6358:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6359:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
                   6360:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                                                         \
                   6361:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6362:                 }else{
                   6363:                   first=0;
                   6364:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6365:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6366:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6367:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
                   6368:                           mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),                                 \
                   6369:                           mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                   6370:                 }/* if first */
                   6371:               } /* age mod 5 */
                   6372:             } /* end loop age */
                   6373:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6374:             first=1;
                   6375:           } /*l12 */
                   6376:         } /* k12 */
                   6377:        } /*l1 */
                   6378:      }/* k1 */
                   6379:    }  /* loop on combination of covariates j1 */
                   6380:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6381:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6382:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6383:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6384:    free_vector(xp,1,npar);
                   6385:    fclose(ficresprob);
                   6386:    fclose(ficresprobcov);
                   6387:    fclose(ficresprobcor);
                   6388:    fflush(ficgp);
                   6389:    fflush(fichtmcov);
                   6390:  }
1.126     brouard  6391: 
                   6392: 
                   6393: /******************* Printing html file ***********/
1.201     brouard  6394: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6395:                  int lastpass, int stepm, int weightopt, char model[],\
                   6396:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6397:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6398:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6399:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6400:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6401: 
                   6402:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6403:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6404: </ul>");
1.237     brouard  6405:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6406: </ul>", model);
1.214     brouard  6407:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6408:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6409:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6410:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6411:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6412:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6413:    fprintf(fichtm,"\
                   6414:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6415:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6416:    fprintf(fichtm,"\
1.217     brouard  6417:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6418:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6419:    fprintf(fichtm,"\
1.126     brouard  6420:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6421:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6422:    fprintf(fichtm,"\
1.217     brouard  6423:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6424:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6425:    fprintf(fichtm,"\
1.211     brouard  6426:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6427:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6428:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6429:    if(prevfcast==1){
                   6430:      fprintf(fichtm,"\
                   6431:  - Prevalence projections by age and states:                           \
1.201     brouard  6432:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6433:    }
1.126     brouard  6434: 
1.222     brouard  6435:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
1.126     brouard  6436: 
1.225     brouard  6437:    m=pow(2,cptcoveff);
1.222     brouard  6438:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6439: 
1.222     brouard  6440:    jj1=0;
1.237     brouard  6441: 
                   6442:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6443:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6444:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6445:        continue;
1.220     brouard  6446: 
1.222     brouard  6447:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6448:      jj1++;
                   6449:      if (cptcovn > 0) {
                   6450:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6451:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6452:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6453:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6454:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6455:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6456:        }
1.237     brouard  6457:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6458:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6459:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6460:       }
                   6461:        
1.230     brouard  6462:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6463:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6464:        if(invalidvarcomb[k1]){
                   6465:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6466:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6467:         continue;
                   6468:        }
                   6469:      }
                   6470:      /* aij, bij */
1.259     brouard  6471:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6472: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6473:      /* Pij */
1.241     brouard  6474:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6475: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6476:      /* Quasi-incidences */
                   6477:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6478:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6479:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6480: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6481: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6482:      /* Survival functions (period) in state j */
                   6483:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6484:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6485: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6486:      }
                   6487:      /* State specific survival functions (period) */
                   6488:      for(cpt=1; cpt<=nlstate;cpt++){
                   6489:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6490:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6491:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6492:      }
                   6493:      /* Period (stable) prevalence in each health state */
                   6494:      for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6495:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d some years earlier, knowing that we will be in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6496: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6497:      }
                   6498:      if(backcast==1){
                   6499:        /* Period (stable) back prevalence in each health state */
                   6500:        for(cpt=1; cpt<=nlstate;cpt++){
1.255     brouard  6501:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability to be in state %d at a younger age, knowing that we will be in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6502: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6503:        }
1.217     brouard  6504:      }
1.222     brouard  6505:      if(prevfcast==1){
                   6506:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6507:        for(cpt=1; cpt<=nlstate;cpt++){
1.258     brouard  6508:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6509: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6510:        }
                   6511:      }
1.220     brouard  6512:         
1.222     brouard  6513:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6514:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6515: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6516:      }
                   6517:      /* } /\* end i1 *\/ */
                   6518:    }/* End k1 */
                   6519:    fprintf(fichtm,"</ul>");
1.126     brouard  6520: 
1.222     brouard  6521:    fprintf(fichtm,"\
1.126     brouard  6522: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6523:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6524:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6525: But because parameters are usually highly correlated (a higher incidence of disability \
                   6526: and a higher incidence of recovery can give very close observed transition) it might \
                   6527: be very useful to look not only at linear confidence intervals estimated from the \
                   6528: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6529: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6530: covariance matrix of the one-step probabilities. \
                   6531: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6532: 
1.222     brouard  6533:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6534:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6535:    fprintf(fichtm,"\
1.126     brouard  6536:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6537:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6538: 
1.222     brouard  6539:    fprintf(fichtm,"\
1.126     brouard  6540:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6541:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6542:    fprintf(fichtm,"\
1.126     brouard  6543:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6544:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6545:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6546:    fprintf(fichtm,"\
1.126     brouard  6547:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6548:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6549:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6550:    fprintf(fichtm,"\
1.128     brouard  6551:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6552:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6553:    fprintf(fichtm,"\
1.128     brouard  6554:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6555:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6556:    fprintf(fichtm,"\
1.126     brouard  6557:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6558:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6559: 
                   6560: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6561: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6562: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6563: /*     <br>",fileres,fileres,fileres,fileres); */
                   6564: /*  else  */
                   6565: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6566:    fflush(fichtm);
                   6567:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6568: 
1.225     brouard  6569:    m=pow(2,cptcoveff);
1.222     brouard  6570:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6571: 
1.222     brouard  6572:    jj1=0;
1.237     brouard  6573: 
1.241     brouard  6574:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6575:    for(k1=1; k1<=m;k1++){
1.253     brouard  6576:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6577:        continue;
1.222     brouard  6578:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6579:      jj1++;
1.126     brouard  6580:      if (cptcovn > 0) {
                   6581:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6582:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6583:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6584:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6585:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6586:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6587:       }
                   6588: 
1.126     brouard  6589:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6590: 
1.222     brouard  6591:        if(invalidvarcomb[k1]){
                   6592:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6593:         continue;
                   6594:        }
1.126     brouard  6595:      }
                   6596:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6597:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6598: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6599: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6600:      }
                   6601:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6602: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6603: true period expectancies (those weighted with period prevalences are also\
                   6604:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6605:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6606: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6607:      /* } /\* end i1 *\/ */
                   6608:    }/* End k1 */
1.241     brouard  6609:   }/* End nres */
1.222     brouard  6610:    fprintf(fichtm,"</ul>");
                   6611:    fflush(fichtm);
1.126     brouard  6612: }
                   6613: 
                   6614: /******************* Gnuplot file **************/
1.223     brouard  6615: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[]){
1.126     brouard  6616: 
                   6617:   char dirfileres[132],optfileres[132];
1.223     brouard  6618:   char gplotcondition[132];
1.237     brouard  6619:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6620:   int lv=0, vlv=0, kl=0;
1.130     brouard  6621:   int ng=0;
1.201     brouard  6622:   int vpopbased;
1.223     brouard  6623:   int ioffset; /* variable offset for columns */
1.235     brouard  6624:   int nres=0; /* Index of resultline */
1.219     brouard  6625: 
1.126     brouard  6626: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6627: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6628: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6629: /*   } */
                   6630: 
                   6631:   /*#ifdef windows */
                   6632:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6633:   /*#endif */
1.225     brouard  6634:   m=pow(2,cptcoveff);
1.126     brouard  6635: 
1.202     brouard  6636:   /* Contribution to likelihood */
                   6637:   /* Plot the probability implied in the likelihood */
1.223     brouard  6638:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6639:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6640:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6641:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6642: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6643:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6644: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6645:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6646:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6647:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6648:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6649:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6650:   for (i=1; i<= nlstate ; i ++) {
                   6651:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6652:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6653:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6654:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6655:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6656:     }
                   6657:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6658:   }
                   6659:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6660:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6661:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6662:   fprintf(ficgp,"\nset out;unset log\n");
                   6663:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6664: 
1.126     brouard  6665:   strcpy(dirfileres,optionfilefiname);
                   6666:   strcpy(optfileres,"vpl");
1.223     brouard  6667:   /* 1eme*/
1.238     brouard  6668:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6669:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6670:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6671:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6672:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6673:          continue;
                   6674:        /* We are interested in selected combination by the resultline */
1.246     brouard  6675:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6676:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
                   6677:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6678:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6679:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6680:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6681:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6682:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6683:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6684:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6685:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6686:        }
                   6687:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  6688:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  6689:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6690:        }       
1.246     brouard  6691:        /* printf("\n#\n"); */
1.238     brouard  6692:        fprintf(ficgp,"\n#\n");
                   6693:        if(invalidvarcomb[k1]){
1.260     brouard  6694:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  6695:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6696:          continue;
                   6697:        }
1.235     brouard  6698:       
1.241     brouard  6699:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   6700:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.260     brouard  6701:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   6702:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   6703:       /* k1-1 error should be nres-1*/
1.238     brouard  6704:        for (i=1; i<= nlstate ; i ++) {
                   6705:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6706:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   6707:        }
1.260     brouard  6708:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  6709:        for (i=1; i<= nlstate ; i ++) {
                   6710:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6711:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6712:        } 
1.260     brouard  6713:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  6714:        for (i=1; i<= nlstate ; i ++) {
                   6715:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   6716:          else fprintf(ficgp," %%*lf (%%*lf)");
                   6717:        }  
                   6718:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
                   6719:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   6720:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  6721:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  6722:          if(cptcoveff ==0){
1.245     brouard  6723:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  6724:          }else{
                   6725:            kl=0;
                   6726:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   6727:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   6728:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6729:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6730:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6731:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  6732:              kl++;
1.238     brouard  6733:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   6734:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   6735:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   6736:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   6737:              if(k==cptcoveff){
1.245     brouard  6738:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  6739:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  6740:              }else{
                   6741:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   6742:                kl++;
                   6743:              }
                   6744:            } /* end covariate */
                   6745:          } /* end if no covariate */
                   6746:        } /* end if backcast */
                   6747:        fprintf(ficgp,"\nset out \n");
                   6748:       } /* nres */
1.201     brouard  6749:     } /* k1 */
                   6750:   } /* cpt */
1.235     brouard  6751: 
                   6752:   
1.126     brouard  6753:   /*2 eme*/
1.238     brouard  6754:   for (k1=1; k1<= m ; k1 ++){  
                   6755:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6756:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6757:        continue;
                   6758:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
                   6759:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  6760:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  6761:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6762:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6763:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6764:        vlv= nbcode[Tvaraff[k]][lv];
                   6765:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6766:       }
1.237     brouard  6767:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  6768:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  6769:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  6770:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  6771:       }
1.211     brouard  6772:       fprintf(ficgp,"\n#\n");
1.223     brouard  6773:       if(invalidvarcomb[k1]){
                   6774:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6775:        continue;
                   6776:       }
1.219     brouard  6777:                        
1.241     brouard  6778:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  6779:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
                   6780:        if(vpopbased==0)
                   6781:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
                   6782:        else
                   6783:          fprintf(ficgp,"\nreplot ");
                   6784:        for (i=1; i<= nlstate+1 ; i ++) {
                   6785:          k=2*i;
1.261     brouard  6786:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  6787:          for (j=1; j<= nlstate+1 ; j ++) {
                   6788:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6789:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6790:          }   
                   6791:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   6792:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  6793:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6794:          for (j=1; j<= nlstate+1 ; j ++) {
                   6795:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6796:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6797:          }   
                   6798:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  6799:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  6800:          for (j=1; j<= nlstate+1 ; j ++) {
                   6801:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   6802:            else fprintf(ficgp," %%*lf (%%*lf)");
                   6803:          }   
                   6804:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   6805:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   6806:        } /* state */
                   6807:       } /* vpopbased */
1.244     brouard  6808:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  6809:     } /* end nres */
                   6810:   } /* k1 end 2 eme*/
                   6811:        
                   6812:        
                   6813:   /*3eme*/
                   6814:   for (k1=1; k1<= m ; k1 ++){
                   6815:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6816:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6817:        continue;
                   6818: 
                   6819:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  6820:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.238     brouard  6821:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6822:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6823:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6824:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6825:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6826:          vlv= nbcode[Tvaraff[k]][lv];
                   6827:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6828:        }
                   6829:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6830:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6831:        }       
                   6832:        fprintf(ficgp,"\n#\n");
                   6833:        if(invalidvarcomb[k1]){
                   6834:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6835:          continue;
                   6836:        }
                   6837:                        
                   6838:        /*       k=2+nlstate*(2*cpt-2); */
                   6839:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  6840:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.238     brouard  6841:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  6842: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  6843:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6844:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6845:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   6846:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   6847:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   6848:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  6849:                                
1.238     brouard  6850:        */
                   6851:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  6852:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  6853:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  6854:                                
1.238     brouard  6855:        } 
1.261     brouard  6856:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  6857:       }
                   6858:     } /* end nres */
                   6859:   } /* end kl 3eme */
1.126     brouard  6860:   
1.223     brouard  6861:   /* 4eme */
1.201     brouard  6862:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  6863:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   6864:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6865:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  6866:        continue;
1.238     brouard  6867:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
                   6868:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   6869:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6870:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6871:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6872:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6873:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6874:          vlv= nbcode[Tvaraff[k]][lv];
                   6875:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6876:        }
                   6877:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6878:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6879:        }       
                   6880:        fprintf(ficgp,"\n#\n");
                   6881:        if(invalidvarcomb[k1]){
                   6882:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6883:          continue;
1.223     brouard  6884:        }
1.238     brouard  6885:       
1.241     brouard  6886:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.238     brouard  6887:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6888: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6889:        k=3;
                   6890:        for (i=1; i<= nlstate ; i ++){
                   6891:          if(i==1){
                   6892:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6893:          }else{
                   6894:            fprintf(ficgp,", '' ");
                   6895:          }
                   6896:          l=(nlstate+ndeath)*(i-1)+1;
                   6897:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6898:          for (j=2; j<= nlstate+ndeath ; j ++)
                   6899:            fprintf(ficgp,"+$%d",k+l+j-1);
                   6900:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   6901:        } /* nlstate */
                   6902:        fprintf(ficgp,"\nset out\n");
                   6903:       } /* end cpt state*/ 
                   6904:     } /* end nres */
                   6905:   } /* end covariate k1 */  
                   6906: 
1.220     brouard  6907: /* 5eme */
1.201     brouard  6908:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  6909:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   6910:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6911:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  6912:        continue;
1.238     brouard  6913:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
                   6914:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   6915:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   6916:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6917:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6918:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6919:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6920:          vlv= nbcode[Tvaraff[k]][lv];
                   6921:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   6922:        }
                   6923:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6924:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6925:        }       
                   6926:        fprintf(ficgp,"\n#\n");
                   6927:        if(invalidvarcomb[k1]){
                   6928:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6929:          continue;
                   6930:        }
1.227     brouard  6931:       
1.241     brouard  6932:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.238     brouard  6933:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   6934: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   6935:        k=3;
                   6936:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6937:          if(j==1)
                   6938:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6939:          else
                   6940:            fprintf(ficgp,", '' ");
                   6941:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6942:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   6943:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   6944:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   6945:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   6946:        } /* nlstate */
                   6947:        fprintf(ficgp,", '' ");
                   6948:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   6949:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   6950:          l=(nlstate+ndeath)*(cpt-1) +j;
                   6951:          if(j < nlstate)
                   6952:            fprintf(ficgp,"$%d +",k+l);
                   6953:          else
                   6954:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   6955:        }
                   6956:        fprintf(ficgp,"\nset out\n");
                   6957:       } /* end cpt state*/ 
                   6958:     } /* end covariate */  
                   6959:   } /* end nres */
1.227     brouard  6960:   
1.220     brouard  6961: /* 6eme */
1.202     brouard  6962:   /* CV preval stable (period) for each covariate */
1.237     brouard  6963:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   6964:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  6965:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6966:       continue;
1.255     brouard  6967:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.227     brouard  6968:       
1.211     brouard  6969:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  6970:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  6971:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   6972:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6973:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6974:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6975:        vlv= nbcode[Tvaraff[k]][lv];
                   6976:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  6977:       }
1.237     brouard  6978:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6979:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6980:       }        
1.211     brouard  6981:       fprintf(ficgp,"\n#\n");
1.223     brouard  6982:       if(invalidvarcomb[k1]){
1.227     brouard  6983:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   6984:        continue;
1.223     brouard  6985:       }
1.227     brouard  6986:       
1.241     brouard  6987:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.126     brouard  6988:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  6989: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  6990:       k=3; /* Offset */
1.255     brouard  6991:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  6992:        if(i==1)
                   6993:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   6994:        else
                   6995:          fprintf(ficgp,", '' ");
1.255     brouard  6996:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  6997:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   6998:        for (j=2; j<= nlstate ; j ++)
                   6999:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7000:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7001:       } /* nlstate */
1.201     brouard  7002:       fprintf(ficgp,"\nset out\n");
1.153     brouard  7003:     } /* end cpt state*/ 
                   7004:   } /* end covariate */  
1.227     brouard  7005:   
                   7006:   
1.220     brouard  7007: /* 7eme */
1.218     brouard  7008:   if(backcast == 1){
1.217     brouard  7009:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7010:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7011:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7012:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7013:        continue;
1.255     brouard  7014:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life ending state */
                   7015:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7016:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7017:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7018:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7019:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7020:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7021:          vlv= nbcode[Tvaraff[k]][lv];
                   7022:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7023:        }
1.237     brouard  7024:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7025:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7026:        }       
1.227     brouard  7027:        fprintf(ficgp,"\n#\n");
                   7028:        if(invalidvarcomb[k1]){
                   7029:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7030:          continue;
                   7031:        }
                   7032:        
1.241     brouard  7033:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.227     brouard  7034:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7035: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7036:        k=3; /* Offset */
1.255     brouard  7037:        for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7038:          if(i==1)
                   7039:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7040:          else
                   7041:            fprintf(ficgp,", '' ");
                   7042:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7043:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7044:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7045:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7046:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7047:          /* for (j=2; j<= nlstate ; j ++) */
                   7048:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7049:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
                   7050:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",i,cpt);
                   7051:        } /* nlstate */
                   7052:        fprintf(ficgp,"\nset out\n");
1.218     brouard  7053:       } /* end cpt state*/ 
                   7054:     } /* end covariate */  
                   7055:   } /* End if backcast */
                   7056:   
1.223     brouard  7057:   /* 8eme */
1.218     brouard  7058:   if(prevfcast==1){
                   7059:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7060:     
1.237     brouard  7061:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7062:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7063:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7064:        continue;
1.211     brouard  7065:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.227     brouard  7066:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7067:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7068:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7069:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7070:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7071:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7072:          vlv= nbcode[Tvaraff[k]][lv];
                   7073:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7074:        }
1.237     brouard  7075:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7076:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7077:        }       
1.227     brouard  7078:        fprintf(ficgp,"\n#\n");
                   7079:        if(invalidvarcomb[k1]){
                   7080:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7081:          continue;
                   7082:        }
                   7083:        
                   7084:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7085:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.227     brouard  7086:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7087: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7088:        for (i=1; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7089:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7090:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7091:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7092:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7093:          if(i==1){
                   7094:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7095:          }else{
                   7096:            fprintf(ficgp,",\\\n '' ");
                   7097:          }
                   7098:          if(cptcoveff ==0){ /* No covariate */
                   7099:            ioffset=2; /* Age is in 2 */
                   7100:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7101:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7102:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7103:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7104:            fprintf(ficgp," u %d:(", ioffset); 
                   7105:            if(i==nlstate+1)
                   7106:              fprintf(ficgp," $%d/(1.-$%d)) t 'pw.%d' with line ",      \
                   7107:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7108:            else
                   7109:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7110:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7111:          }else{ /* more than 2 covariates */
                   7112:            if(cptcoveff ==1){
                   7113:              ioffset=4; /* Age is in 4 */
                   7114:            }else{
                   7115:              ioffset=6; /* Age is in 6 */
                   7116:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7117:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7118:            }   
                   7119:            fprintf(ficgp," u %d:(",ioffset); 
                   7120:            kl=0;
                   7121:            strcpy(gplotcondition,"(");
                   7122:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7123:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7124:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7125:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7126:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7127:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7128:              kl++;
                   7129:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7130:              kl++;
                   7131:              if(k <cptcoveff && cptcoveff>1)
                   7132:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7133:            }
                   7134:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7135:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7136:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7137:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7138:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7139:            if(i==nlstate+1){
                   7140:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p.%d' with line ", gplotcondition, \
                   7141:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7142:            }else{
                   7143:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7144:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7145:            }
                   7146:          } /* end if covariate */
                   7147:        } /* nlstate */
                   7148:        fprintf(ficgp,"\nset out\n");
1.223     brouard  7149:       } /* end cpt state*/
                   7150:     } /* end covariate */
                   7151:   } /* End if prevfcast */
1.227     brouard  7152:   
                   7153:   
1.238     brouard  7154:   /* 9eme writing MLE parameters */
                   7155:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7156:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7157:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7158:     for(k=1; k <=(nlstate+ndeath); k++){
                   7159:       if (k != i) {
1.227     brouard  7160:        fprintf(ficgp,"#   current state %d\n",k);
                   7161:        for(j=1; j <=ncovmodel; j++){
                   7162:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7163:          jk++; 
                   7164:        }
                   7165:        fprintf(ficgp,"\n");
1.126     brouard  7166:       }
                   7167:     }
1.223     brouard  7168:   }
1.187     brouard  7169:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7170:   
1.145     brouard  7171:   /*goto avoid;*/
1.238     brouard  7172:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7173:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7174:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7175:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7176:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7177:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7178:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7179:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7180:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7181:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7182:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7183:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7184:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7185:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7186:   fprintf(ficgp,"#\n");
1.223     brouard  7187:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7188:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7189:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7190:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.237     brouard  7191:     fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7192:     for(jk=1; jk <=m; jk++)  /* For each combination of covariate */
                   7193:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7194:       if(m != 1 && TKresult[nres]!= jk)
1.237     brouard  7195:        continue;
                   7196:       fprintf(ficgp,"# Combination of dummy  jk=%d and ",jk);
                   7197:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7198:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7199:       }        
                   7200:       fprintf(ficgp,"\n#\n");
1.241     brouard  7201:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng,nres);
1.223     brouard  7202:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7203:       if (ng==1){
                   7204:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7205:        fprintf(ficgp,"\nunset log y");
                   7206:       }else if (ng==2){
                   7207:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7208:        fprintf(ficgp,"\nset log y");
                   7209:       }else if (ng==3){
                   7210:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7211:        fprintf(ficgp,"\nset log y");
                   7212:       }else
                   7213:        fprintf(ficgp,"\nunset title ");
                   7214:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7215:       i=1;
                   7216:       for(k2=1; k2<=nlstate; k2++) {
                   7217:        k3=i;
                   7218:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7219:          if (k != k2){
                   7220:            switch( ng) {
                   7221:            case 1:
                   7222:              if(nagesqr==0)
                   7223:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7224:              else /* nagesqr =1 */
                   7225:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7226:              break;
                   7227:            case 2: /* ng=2 */
                   7228:              if(nagesqr==0)
                   7229:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7230:              else /* nagesqr =1 */
                   7231:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7232:              break;
                   7233:            case 3:
                   7234:              if(nagesqr==0)
                   7235:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7236:              else /* nagesqr =1 */
                   7237:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7238:              break;
                   7239:            }
                   7240:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7241:            ijp=1; /* product no age */
                   7242:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7243:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7244:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.237     brouard  7245:              if(j==Tage[ij]) { /* Product by age */
                   7246:                if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
1.238     brouard  7247:                  if(DummyV[j]==0){
1.237     brouard  7248:                    fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7249:                  }else{ /* quantitative */
                   7250:                    fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7251:                    /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7252:                  }
                   7253:                  ij++;
                   7254:                }
                   7255:              }else if(j==Tprod[ijp]) { /* */ 
                   7256:                /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7257:                if(ijp <=cptcovprod) { /* Product */
1.238     brouard  7258:                  if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7259:                    if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
1.237     brouard  7260:                      /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],nbcode[Tvard[ijp][2]][codtabm(jk,j)]); */
                   7261:                      fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7262:                    }else{ /* Vn is dummy and Vm is quanti */
                   7263:                      /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(jk,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7264:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7265:                    }
                   7266:                  }else{ /* Vn*Vm Vn is quanti */
1.238     brouard  7267:                    if(DummyV[Tvard[ijp][2]]==0){
1.237     brouard  7268:                      fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7269:                    }else{ /* Both quanti */
                   7270:                      fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7271:                    }
                   7272:                  }
1.238     brouard  7273:                  ijp++;
1.237     brouard  7274:                }
                   7275:              } else{  /* simple covariate */
                   7276:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(jk,j)]); /\* Valgrind bug nbcode *\/ */
                   7277:                if(Dummy[j]==0){
                   7278:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7279:                }else{ /* quantitative */
                   7280:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.223     brouard  7281:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7282:                }
1.237     brouard  7283:              } /* end simple */
                   7284:            } /* end j */
1.223     brouard  7285:          }else{
                   7286:            i=i-ncovmodel;
                   7287:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7288:              fprintf(ficgp," (1.");
                   7289:          }
1.227     brouard  7290:          
1.223     brouard  7291:          if(ng != 1){
                   7292:            fprintf(ficgp,")/(1");
1.227     brouard  7293:            
1.223     brouard  7294:            for(k1=1; k1 <=nlstate; k1++){ 
                   7295:              if(nagesqr==0)
                   7296:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                   7297:              else /* nagesqr =1 */
                   7298:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
1.217     brouard  7299:               
1.223     brouard  7300:              ij=1;
                   7301:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.237     brouard  7302:                if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7303:                  if(ij <=cptcovage) { /* Bug valgrind */
1.223     brouard  7304:                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                   7305:                    /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                   7306:                    ij++;
                   7307:                  }
                   7308:                }
                   7309:                else
1.225     brouard  7310:                  fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7311:              }
                   7312:              fprintf(ficgp,")");
                   7313:            }
                   7314:            fprintf(ficgp,")");
                   7315:            if(ng ==2)
                   7316:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7317:            else /* ng= 3 */
                   7318:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7319:          }else{ /* end ng <> 1 */
                   7320:            if( k !=k2) /* logit p11 is hard to draw */
                   7321:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7322:          }
                   7323:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7324:            fprintf(ficgp,",");
                   7325:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7326:            fprintf(ficgp,",");
                   7327:          i=i+ncovmodel;
                   7328:        } /* end k */
                   7329:       } /* end k2 */
                   7330:       fprintf(ficgp,"\n set out\n");
                   7331:     } /* end jk */
                   7332:   } /* end ng */
                   7333:   /* avoid: */
                   7334:   fflush(ficgp); 
1.126     brouard  7335: }  /* end gnuplot */
                   7336: 
                   7337: 
                   7338: /*************** Moving average **************/
1.219     brouard  7339: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7340:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7341:    
1.222     brouard  7342:    int i, cpt, cptcod;
                   7343:    int modcovmax =1;
                   7344:    int mobilavrange, mob;
                   7345:    int iage=0;
                   7346: 
                   7347:    double sum=0.;
                   7348:    double age;
                   7349:    double *sumnewp, *sumnewm;
                   7350:    double *agemingood, *agemaxgood; /* Currently identical for all covariates */
                   7351:   
                   7352:   
1.225     brouard  7353:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7354:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7355: 
                   7356:    sumnewp = vector(1,ncovcombmax);
                   7357:    sumnewm = vector(1,ncovcombmax);
                   7358:    agemingood = vector(1,ncovcombmax); 
                   7359:    agemaxgood = vector(1,ncovcombmax);
                   7360: 
                   7361:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7362:      sumnewm[cptcod]=0.;
                   7363:      sumnewp[cptcod]=0.;
                   7364:      agemingood[cptcod]=0;
                   7365:      agemaxgood[cptcod]=0;
                   7366:    }
                   7367:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7368:   
                   7369:    if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7370:      if(mobilav==1) mobilavrange=5; /* default */
                   7371:      else mobilavrange=mobilav;
                   7372:      for (age=bage; age<=fage; age++)
                   7373:        for (i=1; i<=nlstate;i++)
                   7374:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7375:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7376:      /* We keep the original values on the extreme ages bage, fage and for 
                   7377:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7378:        we use a 5 terms etc. until the borders are no more concerned. 
                   7379:      */ 
                   7380:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7381:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
                   7382:         for (i=1; i<=nlstate;i++){
                   7383:           for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7384:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7385:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7386:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7387:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7388:             }
                   7389:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
                   7390:           }
                   7391:         }
                   7392:        }/* end age */
                   7393:      }/* end mob */
                   7394:    }else
                   7395:      return -1;
                   7396:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7397:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7398:      if(invalidvarcomb[cptcod]){
                   7399:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7400:        continue;
                   7401:      }
1.219     brouard  7402: 
1.222     brouard  7403:      agemingood[cptcod]=fage-(mob-1)/2;
                   7404:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, finding the youngest wrong */
                   7405:        sumnewm[cptcod]=0.;
                   7406:        for (i=1; i<=nlstate;i++){
                   7407:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7408:        }
                   7409:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7410:         agemingood[cptcod]=age;
                   7411:        }else{ /* bad */
                   7412:         for (i=1; i<=nlstate;i++){
                   7413:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7414:         } /* i */
                   7415:        } /* end bad */
                   7416:      }/* age */
                   7417:      sum=0.;
                   7418:      for (i=1; i<=nlstate;i++){
                   7419:        sum+=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7420:      }
                   7421:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7422:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any descending age!\n",cptcod);
                   7423:        /* for (i=1; i<=nlstate;i++){ */
                   7424:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7425:        /* } /\* i *\/ */
                   7426:      } /* end bad */
                   7427:      /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   7428:      /* From youngest, finding the oldest wrong */
                   7429:      agemaxgood[cptcod]=bage+(mob-1)/2;
                   7430:      for (age=bage+(mob-1)/2; age<=fage; age++){
                   7431:        sumnewm[cptcod]=0.;
                   7432:        for (i=1; i<=nlstate;i++){
                   7433:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7434:        }
                   7435:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7436:         agemaxgood[cptcod]=age;
                   7437:        }else{ /* bad */
                   7438:         for (i=1; i<=nlstate;i++){
                   7439:           mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7440:         } /* i */
                   7441:        } /* end bad */
                   7442:      }/* age */
                   7443:      sum=0.;
                   7444:      for (i=1; i<=nlstate;i++){
                   7445:        sum+=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7446:      }
                   7447:      if(fabs(sum - 1.) > 1.e-3) { /* bad */
                   7448:        printf("For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one at any ascending age!\n",cptcod);
                   7449:        /* for (i=1; i<=nlstate;i++){ */
                   7450:        /*   mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   7451:        /* } /\* i *\/ */
                   7452:      } /* end bad */
                   7453:                
                   7454:      for (age=bage; age<=fage; age++){
1.235     brouard  7455:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  7456:        sumnewp[cptcod]=0.;
                   7457:        sumnewm[cptcod]=0.;
                   7458:        for (i=1; i<=nlstate;i++){
                   7459:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   7460:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7461:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   7462:        }
                   7463:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   7464:      }
                   7465:      /* printf("\n"); */
                   7466:      /* } */
                   7467:      /* brutal averaging */
                   7468:      for (i=1; i<=nlstate;i++){
                   7469:        for (age=1; age<=bage; age++){
                   7470:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   7471:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7472:        }       
                   7473:        for (age=fage; age<=AGESUP; age++){
                   7474:         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   7475:         /* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); */
                   7476:        }
                   7477:      } /* end i status */
                   7478:      for (i=nlstate+1; i<=nlstate+ndeath;i++){
                   7479:        for (age=1; age<=AGESUP; age++){
                   7480:         /*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*/
                   7481:         mobaverage[(int)age][i][cptcod]=0.;
                   7482:        }
                   7483:      }
                   7484:    }/* end cptcod */
                   7485:    free_vector(sumnewm,1, ncovcombmax);
                   7486:    free_vector(sumnewp,1, ncovcombmax);
                   7487:    free_vector(agemaxgood,1, ncovcombmax);
                   7488:    free_vector(agemingood,1, ncovcombmax);
                   7489:    return 0;
                   7490:  }/* End movingaverage */
1.218     brouard  7491:  
1.126     brouard  7492: 
                   7493: /************** Forecasting ******************/
1.235     brouard  7494:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  7495:   /* proj1, year, month, day of starting projection 
                   7496:      agemin, agemax range of age
                   7497:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   7498:      anproj2 year of en of projection (same day and month as proj1).
                   7499:   */
1.235     brouard  7500:    int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  7501:   double agec; /* generic age */
                   7502:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   7503:   double *popeffectif,*popcount;
                   7504:   double ***p3mat;
1.218     brouard  7505:   /* double ***mobaverage; */
1.126     brouard  7506:   char fileresf[FILENAMELENGTH];
                   7507: 
                   7508:   agelim=AGESUP;
1.211     brouard  7509:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   7510:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   7511:      We still use firstpass and lastpass as another selection.
                   7512:   */
1.214     brouard  7513:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   7514:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  7515:  
1.201     brouard  7516:   strcpy(fileresf,"F_"); 
                   7517:   strcat(fileresf,fileresu);
1.126     brouard  7518:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   7519:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   7520:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   7521:   }
1.235     brouard  7522:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   7523:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  7524: 
1.225     brouard  7525:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  7526: 
                   7527: 
                   7528:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   7529:   if (stepm<=12) stepsize=1;
                   7530:   if(estepm < stepm){
                   7531:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   7532:   }
                   7533:   else  hstepm=estepm;   
                   7534: 
                   7535:   hstepm=hstepm/stepm; 
                   7536:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   7537:                                fractional in yp1 */
                   7538:   anprojmean=yp;
                   7539:   yp2=modf((yp1*12),&yp);
                   7540:   mprojmean=yp;
                   7541:   yp1=modf((yp2*30.5),&yp);
                   7542:   jprojmean=yp;
                   7543:   if(jprojmean==0) jprojmean=1;
                   7544:   if(mprojmean==0) jprojmean=1;
                   7545: 
1.227     brouard  7546:   i1=pow(2,cptcoveff);
1.126     brouard  7547:   if (cptcovn < 1){i1=1;}
                   7548:   
                   7549:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   7550:   
                   7551:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  7552:   
1.126     brouard  7553: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  7554:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   7555:   for(k=1; k<=i1;k++){
1.253     brouard  7556:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  7557:       continue;
1.227     brouard  7558:     if(invalidvarcomb[k]){
                   7559:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   7560:       continue;
                   7561:     }
                   7562:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   7563:     for(j=1;j<=cptcoveff;j++) {
                   7564:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7565:     }
1.235     brouard  7566:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7567:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  7568:     }
1.227     brouard  7569:     fprintf(ficresf," yearproj age");
                   7570:     for(j=1; j<=nlstate+ndeath;j++){ 
                   7571:       for(i=1; i<=nlstate;i++)               
                   7572:        fprintf(ficresf," p%d%d",i,j);
                   7573:       fprintf(ficresf," wp.%d",j);
                   7574:     }
                   7575:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   7576:       fprintf(ficresf,"\n");
                   7577:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   7578:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   7579:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   7580:        nhstepm = nhstepm/hstepm; 
                   7581:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7582:        oldm=oldms;savm=savms;
1.235     brouard  7583:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.227     brouard  7584:        
                   7585:        for (h=0; h<=nhstepm; h++){
                   7586:          if (h*hstepm/YEARM*stepm ==yearp) {
                   7587:            fprintf(ficresf,"\n");
                   7588:            for(j=1;j<=cptcoveff;j++) 
                   7589:              fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   7590:            fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   7591:          } 
                   7592:          for(j=1; j<=nlstate+ndeath;j++) {
                   7593:            ppij=0.;
                   7594:            for(i=1; i<=nlstate;i++) {
                   7595:              if (mobilav==1) 
                   7596:                ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][k];
                   7597:              else {
                   7598:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   7599:              }
                   7600:              if (h*hstepm/YEARM*stepm== yearp) {
                   7601:                fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   7602:              }
                   7603:            } /* end i */
                   7604:            if (h*hstepm/YEARM*stepm==yearp) {
                   7605:              fprintf(ficresf," %.3f", ppij);
                   7606:            }
                   7607:          }/* end j */
                   7608:        } /* end h */
                   7609:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   7610:       } /* end agec */
                   7611:     } /* end yearp */
                   7612:   } /* end  k */
1.219     brouard  7613:        
1.126     brouard  7614:   fclose(ficresf);
1.215     brouard  7615:   printf("End of Computing forecasting \n");
                   7616:   fprintf(ficlog,"End of Computing forecasting\n");
                   7617: 
1.126     brouard  7618: }
                   7619: 
1.218     brouard  7620: /* /\************** Back Forecasting ******************\/ */
1.225     brouard  7621: /* void prevbackforecast(char fileres[], double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
1.218     brouard  7622: /*   /\* back1, year, month, day of starting backection  */
                   7623: /*      agemin, agemax range of age */
                   7624: /*      dateprev1 dateprev2 range of dates during which prevalence is computed */
                   7625: /*      anback2 year of en of backection (same day and month as back1). */
                   7626: /*   *\/ */
                   7627: /*   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1; */
                   7628: /*   double agec; /\* generic age *\/ */
                   7629: /*   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean; */
                   7630: /*   double *popeffectif,*popcount; */
                   7631: /*   double ***p3mat; */
                   7632: /*   /\* double ***mobaverage; *\/ */
                   7633: /*   char fileresfb[FILENAMELENGTH]; */
                   7634:        
                   7635: /*   agelim=AGESUP; */
                   7636: /*   /\* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people */
                   7637: /*      in each health status at the date of interview (if between dateprev1 and dateprev2). */
                   7638: /*      We still use firstpass and lastpass as another selection. */
                   7639: /*   *\/ */
                   7640: /*   /\* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ *\/ */
                   7641: /*   /\*             firstpass, lastpass,  stepm,  weightopt, model); *\/ */
                   7642: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   7643:        
                   7644: /*   strcpy(fileresfb,"FB_");  */
                   7645: /*   strcat(fileresfb,fileresu); */
                   7646: /*   if((ficresfb=fopen(fileresfb,"w"))==NULL) { */
                   7647: /*     printf("Problem with back forecast resultfile: %s\n", fileresfb); */
                   7648: /*     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb); */
                   7649: /*   } */
                   7650: /*   printf("Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7651: /*   fprintf(ficlog,"Computing back forecasting: result on file '%s', please wait... \n", fileresfb); */
                   7652:        
1.225     brouard  7653: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.218     brouard  7654:        
                   7655: /*   /\* if (mobilav!=0) { *\/ */
                   7656: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7657: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7658: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7659: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7660: /*   /\*   } *\/ */
                   7661: /*   /\* } *\/ */
                   7662:        
                   7663: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7664: /*   if (stepm<=12) stepsize=1; */
                   7665: /*   if(estepm < stepm){ */
                   7666: /*     printf ("Problem %d lower than %d\n",estepm, stepm); */
                   7667: /*   } */
                   7668: /*   else  hstepm=estepm;    */
                   7669:        
                   7670: /*   hstepm=hstepm/stepm;  */
                   7671: /*   yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   7672: /*                                fractional in yp1 *\/ */
                   7673: /*   anprojmean=yp; */
                   7674: /*   yp2=modf((yp1*12),&yp); */
                   7675: /*   mprojmean=yp; */
                   7676: /*   yp1=modf((yp2*30.5),&yp); */
                   7677: /*   jprojmean=yp; */
                   7678: /*   if(jprojmean==0) jprojmean=1; */
                   7679: /*   if(mprojmean==0) jprojmean=1; */
                   7680:        
1.225     brouard  7681: /*   i1=cptcoveff; */
1.218     brouard  7682: /*   if (cptcovn < 1){i1=1;} */
1.217     brouard  7683:   
1.218     brouard  7684: /*   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);  */
1.217     brouard  7685:   
1.218     brouard  7686: /*   fprintf(ficresfb,"#****** Routine prevbackforecast **\n"); */
                   7687:        
                   7688: /*     /\*           if (h==(int)(YEARM*yearp)){ *\/ */
                   7689: /*   for(cptcov=1, k=0;cptcov<=i1;cptcov++){ */
1.225     brouard  7690: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
1.218     brouard  7691: /*       k=k+1; */
                   7692: /*       fprintf(ficresfb,"\n#****** hbijx=probability over h years, hp.jx is weighted by observed prev \n#"); */
1.225     brouard  7693: /*       for(j=1;j<=cptcoveff;j++) { */
1.218     brouard  7694: /*                             fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7695: /*       } */
                   7696: /*       fprintf(ficresfb," yearbproj age"); */
                   7697: /*       for(j=1; j<=nlstate+ndeath;j++){  */
                   7698: /*                             for(i=1; i<=nlstate;i++)               */
                   7699: /*           fprintf(ficresfb," p%d%d",i,j); */
                   7700: /*                             fprintf(ficresfb," p.%d",j); */
                   7701: /*       } */
                   7702: /*       for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {  */
                   7703: /*                             /\* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  *\/ */
                   7704: /*                             fprintf(ficresfb,"\n"); */
                   7705: /*                             fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);    */
                   7706: /*                             for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   7707: /*                                     nhstepm=(int) rint((agelim-agec)*YEARM/stepm);  */
                   7708: /*                                     nhstepm = nhstepm/hstepm;  */
                   7709: /*                                     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7710: /*                                     oldm=oldms;savm=savms; */
                   7711: /*                                     hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm,oldm,savm, dnewm, doldm, dsavm, k);       */
                   7712: /*                                     for (h=0; h<=nhstepm; h++){ */
                   7713: /*                                             if (h*hstepm/YEARM*stepm ==yearp) { */
                   7714: /*               fprintf(ficresfb,"\n"); */
1.225     brouard  7715: /*               for(j=1;j<=cptcoveff;j++)  */
1.218     brouard  7716: /*                 fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7717: /*                                                     fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec+h*hstepm/YEARM*stepm); */
                   7718: /*                                             }  */
                   7719: /*                                             for(j=1; j<=nlstate+ndeath;j++) { */
                   7720: /*                                                     ppij=0.; */
                   7721: /*                                                     for(i=1; i<=nlstate;i++) { */
                   7722: /*                                                             if (mobilav==1)  */
                   7723: /*                                                                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod]; */
                   7724: /*                                                             else { */
                   7725: /*                                                                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod]; */
                   7726: /*                                                             } */
                   7727: /*                                                             if (h*hstepm/YEARM*stepm== yearp) { */
                   7728: /*                                                                     fprintf(ficresfb," %.3f", p3mat[i][j][h]); */
                   7729: /*                                                             } */
                   7730: /*                                                     } /\* end i *\/ */
                   7731: /*                                                     if (h*hstepm/YEARM*stepm==yearp) { */
                   7732: /*                                                             fprintf(ficresfb," %.3f", ppij); */
                   7733: /*                                                     } */
                   7734: /*                                             }/\* end j *\/ */
                   7735: /*                                     } /\* end h *\/ */
                   7736: /*                                     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7737: /*                             } /\* end agec *\/ */
                   7738: /*       } /\* end yearp *\/ */
                   7739: /*     } /\* end cptcod *\/ */
                   7740: /*   } /\* end  cptcov *\/ */
                   7741:        
                   7742: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7743:        
                   7744: /*   fclose(ficresfb); */
                   7745: /*   printf("End of Computing Back forecasting \n"); */
                   7746: /*   fprintf(ficlog,"End of Computing Back forecasting\n"); */
1.217     brouard  7747:        
1.218     brouard  7748: /* } */
1.217     brouard  7749: 
1.126     brouard  7750: /************** Forecasting *****not tested NB*************/
1.227     brouard  7751: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  7752:   
1.227     brouard  7753: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   7754: /*   int *popage; */
                   7755: /*   double calagedatem, agelim, kk1, kk2; */
                   7756: /*   double *popeffectif,*popcount; */
                   7757: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   7758: /*   /\* double ***mobaverage; *\/ */
                   7759: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  7760: 
1.227     brouard  7761: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7762: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7763: /*   agelim=AGESUP; */
                   7764: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  7765:   
1.227     brouard  7766: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  7767:   
                   7768:   
1.227     brouard  7769: /*   strcpy(filerespop,"POP_");  */
                   7770: /*   strcat(filerespop,fileresu); */
                   7771: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   7772: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   7773: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   7774: /*   } */
                   7775: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   7776: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  7777: 
1.227     brouard  7778: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  7779: 
1.227     brouard  7780: /*   /\* if (mobilav!=0) { *\/ */
                   7781: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   7782: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   7783: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7784: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   7785: /*   /\*   } *\/ */
                   7786: /*   /\* } *\/ */
1.126     brouard  7787: 
1.227     brouard  7788: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   7789: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  7790:   
1.227     brouard  7791: /*   agelim=AGESUP; */
1.126     brouard  7792:   
1.227     brouard  7793: /*   hstepm=1; */
                   7794: /*   hstepm=hstepm/stepm;  */
1.218     brouard  7795:        
1.227     brouard  7796: /*   if (popforecast==1) { */
                   7797: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   7798: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   7799: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   7800: /*     }  */
                   7801: /*     popage=ivector(0,AGESUP); */
                   7802: /*     popeffectif=vector(0,AGESUP); */
                   7803: /*     popcount=vector(0,AGESUP); */
1.126     brouard  7804:     
1.227     brouard  7805: /*     i=1;    */
                   7806: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  7807:     
1.227     brouard  7808: /*     imx=i; */
                   7809: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   7810: /*   } */
1.218     brouard  7811:   
1.227     brouard  7812: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   7813: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   7814: /*       k=k+1; */
                   7815: /*       fprintf(ficrespop,"\n#******"); */
                   7816: /*       for(j=1;j<=cptcoveff;j++) { */
                   7817: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   7818: /*       } */
                   7819: /*       fprintf(ficrespop,"******\n"); */
                   7820: /*       fprintf(ficrespop,"# Age"); */
                   7821: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   7822: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  7823:       
1.227     brouard  7824: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   7825: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  7826:        
1.227     brouard  7827: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7828: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7829: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7830:          
1.227     brouard  7831: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7832: /*       oldm=oldms;savm=savms; */
                   7833: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  7834:          
1.227     brouard  7835: /*       for (h=0; h<=nhstepm; h++){ */
                   7836: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7837: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7838: /*         }  */
                   7839: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7840: /*           kk1=0.;kk2=0; */
                   7841: /*           for(i=1; i<=nlstate;i++) {               */
                   7842: /*             if (mobilav==1)  */
                   7843: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   7844: /*             else { */
                   7845: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   7846: /*             } */
                   7847: /*           } */
                   7848: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   7849: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   7850: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   7851: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   7852: /*           } */
                   7853: /*         } */
                   7854: /*         for(i=1; i<=nlstate;i++){ */
                   7855: /*           kk1=0.; */
                   7856: /*           for(j=1; j<=nlstate;j++){ */
                   7857: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   7858: /*           } */
                   7859: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   7860: /*         } */
1.218     brouard  7861:            
1.227     brouard  7862: /*         if (h==(int)(calagedatem+12*cpt)) */
                   7863: /*           for(j=1; j<=nlstate;j++)  */
                   7864: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   7865: /*       } */
                   7866: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7867: /*     } */
                   7868: /*       } */
1.218     brouard  7869:       
1.227     brouard  7870: /*       /\******\/ */
1.218     brouard  7871:       
1.227     brouard  7872: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   7873: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   7874: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   7875: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   7876: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  7877:          
1.227     brouard  7878: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7879: /*       oldm=oldms;savm=savms; */
                   7880: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   7881: /*       for (h=0; h<=nhstepm; h++){ */
                   7882: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   7883: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   7884: /*         }  */
                   7885: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   7886: /*           kk1=0.;kk2=0; */
                   7887: /*           for(i=1; i<=nlstate;i++) {               */
                   7888: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   7889: /*           } */
                   7890: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   7891: /*         } */
                   7892: /*       } */
                   7893: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   7894: /*     } */
                   7895: /*       } */
                   7896: /*     }  */
                   7897: /*   } */
1.218     brouard  7898:   
1.227     brouard  7899: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  7900:   
1.227     brouard  7901: /*   if (popforecast==1) { */
                   7902: /*     free_ivector(popage,0,AGESUP); */
                   7903: /*     free_vector(popeffectif,0,AGESUP); */
                   7904: /*     free_vector(popcount,0,AGESUP); */
                   7905: /*   } */
                   7906: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7907: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   7908: /*   fclose(ficrespop); */
                   7909: /* } /\* End of popforecast *\/ */
1.218     brouard  7910:  
1.126     brouard  7911: int fileappend(FILE *fichier, char *optionfich)
                   7912: {
                   7913:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   7914:     printf("Problem with file: %s\n", optionfich);
                   7915:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   7916:     return (0);
                   7917:   }
                   7918:   fflush(fichier);
                   7919:   return (1);
                   7920: }
                   7921: 
                   7922: 
                   7923: /**************** function prwizard **********************/
                   7924: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   7925: {
                   7926: 
                   7927:   /* Wizard to print covariance matrix template */
                   7928: 
1.164     brouard  7929:   char ca[32], cb[32];
                   7930:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  7931:   int numlinepar;
                   7932: 
                   7933:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7934:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   7935:   for(i=1; i <=nlstate; i++){
                   7936:     jj=0;
                   7937:     for(j=1; j <=nlstate+ndeath; j++){
                   7938:       if(j==i) continue;
                   7939:       jj++;
                   7940:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   7941:       printf("%1d%1d",i,j);
                   7942:       fprintf(ficparo,"%1d%1d",i,j);
                   7943:       for(k=1; k<=ncovmodel;k++){
                   7944:        /*        printf(" %lf",param[i][j][k]); */
                   7945:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   7946:        printf(" 0.");
                   7947:        fprintf(ficparo," 0.");
                   7948:       }
                   7949:       printf("\n");
                   7950:       fprintf(ficparo,"\n");
                   7951:     }
                   7952:   }
                   7953:   printf("# Scales (for hessian or gradient estimation)\n");
                   7954:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   7955:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   7956:   for(i=1; i <=nlstate; i++){
                   7957:     jj=0;
                   7958:     for(j=1; j <=nlstate+ndeath; j++){
                   7959:       if(j==i) continue;
                   7960:       jj++;
                   7961:       fprintf(ficparo,"%1d%1d",i,j);
                   7962:       printf("%1d%1d",i,j);
                   7963:       fflush(stdout);
                   7964:       for(k=1; k<=ncovmodel;k++){
                   7965:        /*      printf(" %le",delti3[i][j][k]); */
                   7966:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   7967:        printf(" 0.");
                   7968:        fprintf(ficparo," 0.");
                   7969:       }
                   7970:       numlinepar++;
                   7971:       printf("\n");
                   7972:       fprintf(ficparo,"\n");
                   7973:     }
                   7974:   }
                   7975:   printf("# Covariance matrix\n");
                   7976: /* # 121 Var(a12)\n\ */
                   7977: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7978: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   7979: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   7980: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   7981: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   7982: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   7983: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   7984:   fflush(stdout);
                   7985:   fprintf(ficparo,"# Covariance matrix\n");
                   7986:   /* # 121 Var(a12)\n\ */
                   7987:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   7988:   /* #   ...\n\ */
                   7989:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   7990:   
                   7991:   for(itimes=1;itimes<=2;itimes++){
                   7992:     jj=0;
                   7993:     for(i=1; i <=nlstate; i++){
                   7994:       for(j=1; j <=nlstate+ndeath; j++){
                   7995:        if(j==i) continue;
                   7996:        for(k=1; k<=ncovmodel;k++){
                   7997:          jj++;
                   7998:          ca[0]= k+'a'-1;ca[1]='\0';
                   7999:          if(itimes==1){
                   8000:            printf("#%1d%1d%d",i,j,k);
                   8001:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8002:          }else{
                   8003:            printf("%1d%1d%d",i,j,k);
                   8004:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8005:            /*  printf(" %.5le",matcov[i][j]); */
                   8006:          }
                   8007:          ll=0;
                   8008:          for(li=1;li <=nlstate; li++){
                   8009:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8010:              if(lj==li) continue;
                   8011:              for(lk=1;lk<=ncovmodel;lk++){
                   8012:                ll++;
                   8013:                if(ll<=jj){
                   8014:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8015:                  if(ll<jj){
                   8016:                    if(itimes==1){
                   8017:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8018:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8019:                    }else{
                   8020:                      printf(" 0.");
                   8021:                      fprintf(ficparo," 0.");
                   8022:                    }
                   8023:                  }else{
                   8024:                    if(itimes==1){
                   8025:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8026:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8027:                    }else{
                   8028:                      printf(" 0.");
                   8029:                      fprintf(ficparo," 0.");
                   8030:                    }
                   8031:                  }
                   8032:                }
                   8033:              } /* end lk */
                   8034:            } /* end lj */
                   8035:          } /* end li */
                   8036:          printf("\n");
                   8037:          fprintf(ficparo,"\n");
                   8038:          numlinepar++;
                   8039:        } /* end k*/
                   8040:       } /*end j */
                   8041:     } /* end i */
                   8042:   } /* end itimes */
                   8043: 
                   8044: } /* end of prwizard */
                   8045: /******************* Gompertz Likelihood ******************************/
                   8046: double gompertz(double x[])
                   8047: { 
                   8048:   double A,B,L=0.0,sump=0.,num=0.;
                   8049:   int i,n=0; /* n is the size of the sample */
                   8050: 
1.220     brouard  8051:   for (i=1;i<=imx ; i++) {
1.126     brouard  8052:     sump=sump+weight[i];
                   8053:     /*    sump=sump+1;*/
                   8054:     num=num+1;
                   8055:   }
                   8056:  
                   8057:  
                   8058:   /* for (i=0; i<=imx; i++) 
                   8059:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8060: 
                   8061:   for (i=1;i<=imx ; i++)
                   8062:     {
                   8063:       if (cens[i] == 1 && wav[i]>1)
                   8064:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8065:       
                   8066:       if (cens[i] == 0 && wav[i]>1)
                   8067:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8068:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8069:       
                   8070:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8071:       if (wav[i] > 1 ) { /* ??? */
                   8072:        L=L+A*weight[i];
                   8073:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8074:       }
                   8075:     }
                   8076: 
                   8077:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8078:  
                   8079:   return -2*L*num/sump;
                   8080: }
                   8081: 
1.136     brouard  8082: #ifdef GSL
                   8083: /******************* Gompertz_f Likelihood ******************************/
                   8084: double gompertz_f(const gsl_vector *v, void *params)
                   8085: { 
                   8086:   double A,B,LL=0.0,sump=0.,num=0.;
                   8087:   double *x= (double *) v->data;
                   8088:   int i,n=0; /* n is the size of the sample */
                   8089: 
                   8090:   for (i=0;i<=imx-1 ; i++) {
                   8091:     sump=sump+weight[i];
                   8092:     /*    sump=sump+1;*/
                   8093:     num=num+1;
                   8094:   }
                   8095:  
                   8096:  
                   8097:   /* for (i=0; i<=imx; i++) 
                   8098:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8099:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8100:   for (i=1;i<=imx ; i++)
                   8101:     {
                   8102:       if (cens[i] == 1 && wav[i]>1)
                   8103:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8104:       
                   8105:       if (cens[i] == 0 && wav[i]>1)
                   8106:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8107:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8108:       
                   8109:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8110:       if (wav[i] > 1 ) { /* ??? */
                   8111:        LL=LL+A*weight[i];
                   8112:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8113:       }
                   8114:     }
                   8115: 
                   8116:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8117:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8118:  
                   8119:   return -2*LL*num/sump;
                   8120: }
                   8121: #endif
                   8122: 
1.126     brouard  8123: /******************* Printing html file ***********/
1.201     brouard  8124: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8125:                  int lastpass, int stepm, int weightopt, char model[],\
                   8126:                  int imx,  double p[],double **matcov,double agemortsup){
                   8127:   int i,k;
                   8128: 
                   8129:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8130:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8131:   for (i=1;i<=2;i++) 
                   8132:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8133:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8134:   fprintf(fichtm,"</ul>");
                   8135: 
                   8136: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8137: 
                   8138:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8139: 
                   8140:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8141:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8142: 
                   8143:  
                   8144:   fflush(fichtm);
                   8145: }
                   8146: 
                   8147: /******************* Gnuplot file **************/
1.201     brouard  8148: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8149: 
                   8150:   char dirfileres[132],optfileres[132];
1.164     brouard  8151: 
1.126     brouard  8152:   int ng;
                   8153: 
                   8154: 
                   8155:   /*#ifdef windows */
                   8156:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8157:     /*#endif */
                   8158: 
                   8159: 
                   8160:   strcpy(dirfileres,optionfilefiname);
                   8161:   strcpy(optfileres,"vpl");
1.199     brouard  8162:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8163:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8164:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8165:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8166:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8167: 
                   8168: } 
                   8169: 
1.136     brouard  8170: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8171: {
1.126     brouard  8172: 
1.136     brouard  8173:   /*-------- data file ----------*/
                   8174:   FILE *fic;
                   8175:   char dummy[]="                         ";
1.240     brouard  8176:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8177:   int lstra;
1.136     brouard  8178:   int linei, month, year,iout;
                   8179:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8180:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8181:   char *stratrunc;
1.223     brouard  8182: 
1.240     brouard  8183:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8184:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8185: 
1.240     brouard  8186:   for(v=1; v <=ncovcol;v++){
                   8187:     DummyV[v]=0;
                   8188:     FixedV[v]=0;
                   8189:   }
                   8190:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8191:     DummyV[v]=1;
                   8192:     FixedV[v]=0;
                   8193:   }
                   8194:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8195:     DummyV[v]=0;
                   8196:     FixedV[v]=1;
                   8197:   }
                   8198:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8199:     DummyV[v]=1;
                   8200:     FixedV[v]=1;
                   8201:   }
                   8202:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8203:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8204:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8205:   }
1.126     brouard  8206: 
1.136     brouard  8207:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8208:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8209:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8210:   }
1.126     brouard  8211: 
1.136     brouard  8212:   i=1;
                   8213:   linei=0;
                   8214:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8215:     linei=linei+1;
                   8216:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8217:       if(line[j] == '\t')
                   8218:        line[j] = ' ';
                   8219:     }
                   8220:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8221:       ;
                   8222:     };
                   8223:     line[j+1]=0;  /* Trims blanks at end of line */
                   8224:     if(line[0]=='#'){
                   8225:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8226:       printf("Comment line\n%s\n",line);
                   8227:       continue;
                   8228:     }
                   8229:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8230:     strcpy(line, linetmp);
1.223     brouard  8231:     
                   8232:     /* Loops on waves */
                   8233:     for (j=maxwav;j>=1;j--){
                   8234:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8235:        cutv(stra, strb, line, ' '); 
                   8236:        if(strb[0]=='.') { /* Missing value */
                   8237:          lval=-1;
                   8238:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8239:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8240:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8241:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8242:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8243:            return 1;
                   8244:          }
                   8245:        }else{
                   8246:          errno=0;
                   8247:          /* what_kind_of_number(strb); */
                   8248:          dval=strtod(strb,&endptr); 
                   8249:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   8250:          /* if(strb != endptr && *endptr == '\0') */
                   8251:          /*    dval=dlval; */
                   8252:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8253:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8254:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   8255:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   8256:            return 1;
                   8257:          }
                   8258:          cotqvar[j][iv][i]=dval; 
                   8259:          cotvar[j][ntv+iv][i]=dval; 
                   8260:        }
                   8261:        strcpy(line,stra);
1.223     brouard  8262:       }/* end loop ntqv */
1.225     brouard  8263:       
1.223     brouard  8264:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  8265:        cutv(stra, strb, line, ' '); 
                   8266:        if(strb[0]=='.') { /* Missing value */
                   8267:          lval=-1;
                   8268:        }else{
                   8269:          errno=0;
                   8270:          lval=strtol(strb,&endptr,10); 
                   8271:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8272:          if( strb[0]=='\0' || (*endptr != '\0')){
                   8273:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   8274:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   8275:            return 1;
                   8276:          }
                   8277:        }
                   8278:        if(lval <-1 || lval >1){
                   8279:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8280:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8281:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8282:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8283:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8284:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8285:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8286:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8287:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  8288:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  8289:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8290:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  8291:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8292:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8293:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  8294:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  8295:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  8296:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  8297:          return 1;
                   8298:        }
                   8299:        cotvar[j][iv][i]=(double)(lval);
                   8300:        strcpy(line,stra);
1.223     brouard  8301:       }/* end loop ntv */
1.225     brouard  8302:       
1.223     brouard  8303:       /* Statuses  at wave */
1.137     brouard  8304:       cutv(stra, strb, line, ' '); 
1.223     brouard  8305:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  8306:        lval=-1;
1.136     brouard  8307:       }else{
1.238     brouard  8308:        errno=0;
                   8309:        lval=strtol(strb,&endptr,10); 
                   8310:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   8311:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8312:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   8313:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   8314:          return 1;
                   8315:        }
1.136     brouard  8316:       }
1.225     brouard  8317:       
1.136     brouard  8318:       s[j][i]=lval;
1.225     brouard  8319:       
1.223     brouard  8320:       /* Date of Interview */
1.136     brouard  8321:       strcpy(line,stra);
                   8322:       cutv(stra, strb,line,' ');
1.169     brouard  8323:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8324:       }
1.169     brouard  8325:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  8326:        month=99;
                   8327:        year=9999;
1.136     brouard  8328:       }else{
1.225     brouard  8329:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   8330:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   8331:        return 1;
1.136     brouard  8332:       }
                   8333:       anint[j][i]= (double) year; 
                   8334:       mint[j][i]= (double)month; 
                   8335:       strcpy(line,stra);
1.223     brouard  8336:     } /* End loop on waves */
1.225     brouard  8337:     
1.223     brouard  8338:     /* Date of death */
1.136     brouard  8339:     cutv(stra, strb,line,' '); 
1.169     brouard  8340:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8341:     }
1.169     brouard  8342:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  8343:       month=99;
                   8344:       year=9999;
                   8345:     }else{
1.141     brouard  8346:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  8347:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   8348:       return 1;
1.136     brouard  8349:     }
                   8350:     andc[i]=(double) year; 
                   8351:     moisdc[i]=(double) month; 
                   8352:     strcpy(line,stra);
                   8353:     
1.223     brouard  8354:     /* Date of birth */
1.136     brouard  8355:     cutv(stra, strb,line,' '); 
1.169     brouard  8356:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  8357:     }
1.169     brouard  8358:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  8359:       month=99;
                   8360:       year=9999;
                   8361:     }else{
1.141     brouard  8362:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   8363:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8364:       return 1;
1.136     brouard  8365:     }
                   8366:     if (year==9999) {
1.141     brouard  8367:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   8368:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  8369:       return 1;
                   8370:       
1.136     brouard  8371:     }
                   8372:     annais[i]=(double)(year);
                   8373:     moisnais[i]=(double)(month); 
                   8374:     strcpy(line,stra);
1.225     brouard  8375:     
1.223     brouard  8376:     /* Sample weight */
1.136     brouard  8377:     cutv(stra, strb,line,' '); 
                   8378:     errno=0;
                   8379:     dval=strtod(strb,&endptr); 
                   8380:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  8381:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   8382:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  8383:       fflush(ficlog);
                   8384:       return 1;
                   8385:     }
                   8386:     weight[i]=dval; 
                   8387:     strcpy(line,stra);
1.225     brouard  8388:     
1.223     brouard  8389:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   8390:       cutv(stra, strb, line, ' '); 
                   8391:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  8392:        lval=-1;
1.223     brouard  8393:       }else{
1.225     brouard  8394:        errno=0;
                   8395:        /* what_kind_of_number(strb); */
                   8396:        dval=strtod(strb,&endptr);
                   8397:        /* if(strb != endptr && *endptr == '\0') */
                   8398:        /*   dval=dlval; */
                   8399:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   8400:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8401:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   8402:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   8403:          return 1;
                   8404:        }
                   8405:        coqvar[iv][i]=dval; 
1.226     brouard  8406:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  8407:       }
                   8408:       strcpy(line,stra);
                   8409:     }/* end loop nqv */
1.136     brouard  8410:     
1.223     brouard  8411:     /* Covariate values */
1.136     brouard  8412:     for (j=ncovcol;j>=1;j--){
                   8413:       cutv(stra, strb,line,' '); 
1.223     brouard  8414:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  8415:        lval=-1;
1.136     brouard  8416:       }else{
1.225     brouard  8417:        errno=0;
                   8418:        lval=strtol(strb,&endptr,10); 
                   8419:        if( strb[0]=='\0' || (*endptr != '\0')){
                   8420:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   8421:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   8422:          return 1;
                   8423:        }
1.136     brouard  8424:       }
                   8425:       if(lval <-1 || lval >1){
1.225     brouard  8426:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8427:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8428:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8429:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8430:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8431:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8432:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8433:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8434:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  8435:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  8436:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   8437:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  8438:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   8439:  build V1=0 V2=0 for the reference value (1),\n                                \
                   8440:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  8441:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  8442:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  8443:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  8444:        return 1;
1.136     brouard  8445:       }
                   8446:       covar[j][i]=(double)(lval);
                   8447:       strcpy(line,stra);
                   8448:     }  
                   8449:     lstra=strlen(stra);
1.225     brouard  8450:     
1.136     brouard  8451:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   8452:       stratrunc = &(stra[lstra-9]);
                   8453:       num[i]=atol(stratrunc);
                   8454:     }
                   8455:     else
                   8456:       num[i]=atol(stra);
                   8457:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   8458:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   8459:     
                   8460:     i=i+1;
                   8461:   } /* End loop reading  data */
1.225     brouard  8462:   
1.136     brouard  8463:   *imax=i-1; /* Number of individuals */
                   8464:   fclose(fic);
1.225     brouard  8465:   
1.136     brouard  8466:   return (0);
1.164     brouard  8467:   /* endread: */
1.225     brouard  8468:   printf("Exiting readdata: ");
                   8469:   fclose(fic);
                   8470:   return (1);
1.223     brouard  8471: }
1.126     brouard  8472: 
1.234     brouard  8473: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  8474:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  8475:   while (*p2 == ' ')
1.234     brouard  8476:     p2++; 
                   8477:   /* while ((*p1++ = *p2++) !=0) */
                   8478:   /*   ; */
                   8479:   /* do */
                   8480:   /*   while (*p2 == ' ') */
                   8481:   /*     p2++; */
                   8482:   /* while (*p1++ == *p2++); */
                   8483:   *stri=p2; 
1.145     brouard  8484: }
                   8485: 
1.235     brouard  8486: int decoderesult ( char resultline[], int nres)
1.230     brouard  8487: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   8488: {
1.235     brouard  8489:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  8490:   char resultsav[MAXLINE];
1.234     brouard  8491:   int resultmodel[MAXLINE];
                   8492:   int modelresult[MAXLINE];
1.230     brouard  8493:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   8494: 
1.234     brouard  8495:   removefirstspace(&resultline);
1.233     brouard  8496:   printf("decoderesult:%s\n",resultline);
1.230     brouard  8497: 
                   8498:   if (strstr(resultline,"v") !=0){
                   8499:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   8500:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   8501:     return 1;
                   8502:   }
                   8503:   trimbb(resultsav, resultline);
                   8504:   if (strlen(resultsav) >1){
                   8505:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   8506:   }
1.253     brouard  8507:   if(j == 0){ /* Resultline but no = */
                   8508:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   8509:     return (0);
                   8510:   }
                   8511:     
1.234     brouard  8512:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   8513:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8514:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   8515:   }
                   8516:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   8517:     if(nbocc(resultsav,'=') >1){
                   8518:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   8519:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   8520:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   8521:     }else
                   8522:       cutl(strc,strd,resultsav,'=');
1.230     brouard  8523:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  8524:     
1.230     brouard  8525:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   8526:     Tvarsel[k]=atoi(strc);
                   8527:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   8528:     /* cptcovsel++;     */
                   8529:     if (nbocc(stra,'=') >0)
                   8530:       strcpy(resultsav,stra); /* and analyzes it */
                   8531:   }
1.235     brouard  8532:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  8533:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8534:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  8535:       match=0;
1.236     brouard  8536:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  8537:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  8538:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  8539:          match=1;
                   8540:          break;
                   8541:        }
                   8542:       }
                   8543:       if(match == 0){
                   8544:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8545:       }
                   8546:     }
                   8547:   }
1.235     brouard  8548:   /* Checking for missing or useless values in comparison of current model needs */
                   8549:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  8550:     match=0;
1.235     brouard  8551:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8552:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  8553:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  8554:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  8555:          ++match;
                   8556:        }
                   8557:       }
                   8558:     }
                   8559:     if(match == 0){
                   8560:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   8561:     }else if(match > 1){
                   8562:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   8563:     }
                   8564:   }
1.235     brouard  8565:       
1.234     brouard  8566:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  8567:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8568:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   8569:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   8570:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   8571:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   8572:   /*    1 0 0 0 */
                   8573:   /*    2 1 0 0 */
                   8574:   /*    3 0 1 0 */ 
                   8575:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   8576:   /*    5 0 0 1 */
                   8577:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   8578:   /*    7 0 1 1 */
                   8579:   /*    8 1 1 1 */
1.237     brouard  8580:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   8581:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   8582:   /* V5*age V5 known which value for nres?  */
                   8583:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  8584:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   8585:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  8586:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  8587:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   8588:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  8589:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   8590:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   8591:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  8592:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   8593:       k4++;;
                   8594:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   8595:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   8596:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  8597:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   8598:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   8599:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  8600:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   8601:       k4q++;;
                   8602:     }
                   8603:   }
1.234     brouard  8604:   
1.235     brouard  8605:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  8606:   return (0);
                   8607: }
1.235     brouard  8608: 
1.230     brouard  8609: int decodemodel( char model[], int lastobs)
                   8610:  /**< This routine decodes the model and returns:
1.224     brouard  8611:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   8612:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   8613:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   8614:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   8615:        * - cptcovage number of covariates with age*products =2
                   8616:        * - cptcovs number of simple covariates
                   8617:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   8618:        *     which is a new column after the 9 (ncovcol) variables. 
                   8619:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   8620:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   8621:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   8622:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   8623:        */
1.136     brouard  8624: {
1.238     brouard  8625:   int i, j, k, ks, v;
1.227     brouard  8626:   int  j1, k1, k2, k3, k4;
1.136     brouard  8627:   char modelsav[80];
1.145     brouard  8628:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  8629:   char *strpt;
1.136     brouard  8630: 
1.145     brouard  8631:   /*removespace(model);*/
1.136     brouard  8632:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  8633:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  8634:     if (strstr(model,"AGE") !=0){
1.192     brouard  8635:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   8636:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  8637:       return 1;
                   8638:     }
1.141     brouard  8639:     if (strstr(model,"v") !=0){
                   8640:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   8641:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   8642:       return 1;
                   8643:     }
1.187     brouard  8644:     strcpy(modelsav,model); 
                   8645:     if ((strpt=strstr(model,"age*age")) !=0){
                   8646:       printf(" strpt=%s, model=%s\n",strpt, model);
                   8647:       if(strpt != model){
1.234     brouard  8648:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8649:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8650:  corresponding column of parameters.\n",model);
1.234     brouard  8651:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  8652:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  8653:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  8654:        return 1;
1.225     brouard  8655:       }
1.187     brouard  8656:       nagesqr=1;
                   8657:       if (strstr(model,"+age*age") !=0)
1.234     brouard  8658:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  8659:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  8660:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  8661:       else 
1.234     brouard  8662:        substrchaine(modelsav, model, "age*age");
1.187     brouard  8663:     }else
                   8664:       nagesqr=0;
                   8665:     if (strlen(modelsav) >1){
                   8666:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   8667:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  8668:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  8669:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  8670:                     * cst, age and age*age 
                   8671:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   8672:       /* including age products which are counted in cptcovage.
                   8673:        * but the covariates which are products must be treated 
                   8674:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  8675:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   8676:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  8677:       
                   8678:       
1.187     brouard  8679:       /*   Design
                   8680:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   8681:        *  <          ncovcol=8                >
                   8682:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   8683:        *   k=  1    2      3       4     5       6      7        8
                   8684:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   8685:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  8686:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   8687:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  8688:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   8689:        *  Tage[++cptcovage]=k
                   8690:        *       if products, new covar are created after ncovcol with k1
                   8691:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   8692:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   8693:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   8694:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   8695:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   8696:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   8697:        *  <          ncovcol=8                >
                   8698:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   8699:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   8700:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   8701:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8702:        * p Tprod[1]@2={                         6, 5}
                   8703:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   8704:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   8705:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   8706:        *How to reorganize?
                   8707:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   8708:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   8709:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   8710:        * Struct []
                   8711:        */
1.225     brouard  8712:       
1.187     brouard  8713:       /* This loop fills the array Tvar from the string 'model'.*/
                   8714:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   8715:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   8716:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   8717:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   8718:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   8719:       /*       k=1 Tvar[1]=2 (from V2) */
                   8720:       /*       k=5 Tvar[5] */
                   8721:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  8722:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  8723:       /*       } */
1.198     brouard  8724:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  8725:       /*
                   8726:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  8727:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   8728:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   8729:       }
1.187     brouard  8730:       cptcovage=0;
                   8731:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  8732:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  8733:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  8734:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   8735:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   8736:        /*scanf("%d",i);*/
                   8737:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   8738:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   8739:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   8740:            /* covar is not filled and then is empty */
                   8741:            cptcovprod--;
                   8742:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   8743:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   8744:            Typevar[k]=1;  /* 1 for age product */
                   8745:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   8746:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   8747:            /*printf("stre=%s ", stre);*/
                   8748:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   8749:            cptcovprod--;
                   8750:            cutl(stre,strb,strc,'V');
                   8751:            Tvar[k]=atoi(stre);
                   8752:            Typevar[k]=1;  /* 1 for age product */
                   8753:            cptcovage++;
                   8754:            Tage[cptcovage]=k;
                   8755:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   8756:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   8757:            cptcovn++;
                   8758:            cptcovprodnoage++;k1++;
                   8759:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   8760:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   8761:                                                because this model-covariate is a construction we invent a new column
                   8762:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   8763:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   8764:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   8765:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   8766:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   8767:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   8768:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   8769:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   8770:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   8771:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   8772:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   8773:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  8774:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  8775:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   8776:            for (i=1; i<=lastobs;i++){
                   8777:              /* Computes the new covariate which is a product of
                   8778:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   8779:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   8780:            }
                   8781:          } /* End age is not in the model */
                   8782:        } /* End if model includes a product */
                   8783:        else { /* no more sum */
                   8784:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   8785:          /*  scanf("%d",i);*/
                   8786:          cutl(strd,strc,strb,'V');
                   8787:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   8788:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   8789:          Tvar[k]=atoi(strd);
                   8790:          Typevar[k]=0;  /* 0 for simple covariates */
                   8791:        }
                   8792:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  8793:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  8794:                                  scanf("%d",i);*/
1.187     brouard  8795:       } /* end of loop + on total covariates */
                   8796:     } /* end if strlen(modelsave == 0) age*age might exist */
                   8797:   } /* end if strlen(model == 0) */
1.136     brouard  8798:   
                   8799:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   8800:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  8801:   
1.136     brouard  8802:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  8803:      printf("cptcovprod=%d ", cptcovprod);
                   8804:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   8805:      scanf("%d ",i);*/
                   8806: 
                   8807: 
1.230     brouard  8808: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   8809:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  8810: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   8811:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   8812:    k =           1    2   3     4       5       6      7      8        9
                   8813:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   8814:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  8815:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   8816:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   8817:          Tmodelind[combination of covar]=k;
1.225     brouard  8818: */  
                   8819: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  8820:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  8821:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  8822:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  8823:   printf("Model=%s\n\
                   8824: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8825: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8826: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   8827:   fprintf(ficlog,"Model=%s\n\
                   8828: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   8829: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   8830: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  8831:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  8832:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   8833:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  8834:       Fixed[k]= 0;
                   8835:       Dummy[k]= 0;
1.225     brouard  8836:       ncoveff++;
1.232     brouard  8837:       ncovf++;
1.234     brouard  8838:       nsd++;
                   8839:       modell[k].maintype= FTYPE;
                   8840:       TvarsD[nsd]=Tvar[k];
                   8841:       TvarsDind[nsd]=k;
                   8842:       TvarF[ncovf]=Tvar[k];
                   8843:       TvarFind[ncovf]=k;
                   8844:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8845:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   8846:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   8847:       Fixed[k]= 0;
                   8848:       Dummy[k]= 0;
                   8849:       ncoveff++;
                   8850:       ncovf++;
                   8851:       modell[k].maintype= FTYPE;
                   8852:       TvarF[ncovf]=Tvar[k];
                   8853:       TvarFind[ncovf]=k;
1.230     brouard  8854:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  8855:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  8856:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  8857:       Fixed[k]= 0;
                   8858:       Dummy[k]= 1;
1.230     brouard  8859:       nqfveff++;
1.234     brouard  8860:       modell[k].maintype= FTYPE;
                   8861:       modell[k].subtype= FQ;
                   8862:       nsq++;
                   8863:       TvarsQ[nsq]=Tvar[k];
                   8864:       TvarsQind[nsq]=k;
1.232     brouard  8865:       ncovf++;
1.234     brouard  8866:       TvarF[ncovf]=Tvar[k];
                   8867:       TvarFind[ncovf]=k;
1.231     brouard  8868:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  8869:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  8870:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  8871:       Fixed[k]= 1;
                   8872:       Dummy[k]= 0;
1.225     brouard  8873:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  8874:       modell[k].maintype= VTYPE;
                   8875:       modell[k].subtype= VD;
                   8876:       nsd++;
                   8877:       TvarsD[nsd]=Tvar[k];
                   8878:       TvarsDind[nsd]=k;
                   8879:       ncovv++; /* Only simple time varying variables */
                   8880:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8881:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8882:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   8883:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  8884:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   8885:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  8886:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  8887:       Fixed[k]= 1;
                   8888:       Dummy[k]= 1;
                   8889:       nqtveff++;
                   8890:       modell[k].maintype= VTYPE;
                   8891:       modell[k].subtype= VQ;
                   8892:       ncovv++; /* Only simple time varying variables */
                   8893:       nsq++;
                   8894:       TvarsQ[nsq]=Tvar[k];
                   8895:       TvarsQind[nsq]=k;
                   8896:       TvarV[ncovv]=Tvar[k];
1.242     brouard  8897:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  8898:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   8899:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  8900:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   8901:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   8902:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  8903:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  8904:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  8905:       ncova++;
                   8906:       TvarA[ncova]=Tvar[k];
                   8907:       TvarAind[ncova]=k;
1.231     brouard  8908:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  8909:        Fixed[k]= 2;
                   8910:        Dummy[k]= 2;
                   8911:        modell[k].maintype= ATYPE;
                   8912:        modell[k].subtype= APFD;
                   8913:        /* ncoveff++; */
1.227     brouard  8914:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  8915:        Fixed[k]= 2;
                   8916:        Dummy[k]= 3;
                   8917:        modell[k].maintype= ATYPE;
                   8918:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   8919:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  8920:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  8921:        Fixed[k]= 3;
                   8922:        Dummy[k]= 2;
                   8923:        modell[k].maintype= ATYPE;
                   8924:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   8925:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  8926:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  8927:        Fixed[k]= 3;
                   8928:        Dummy[k]= 3;
                   8929:        modell[k].maintype= ATYPE;
                   8930:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   8931:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  8932:       }
                   8933:     }else if (Typevar[k] == 2) {  /* product without age */
                   8934:       k1=Tposprod[k];
                   8935:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  8936:        if(Tvard[k1][2] <=ncovcol){
                   8937:          Fixed[k]= 1;
                   8938:          Dummy[k]= 0;
                   8939:          modell[k].maintype= FTYPE;
                   8940:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   8941:          ncovf++; /* Fixed variables without age */
                   8942:          TvarF[ncovf]=Tvar[k];
                   8943:          TvarFind[ncovf]=k;
                   8944:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   8945:          Fixed[k]= 0;  /* or 2 ?*/
                   8946:          Dummy[k]= 1;
                   8947:          modell[k].maintype= FTYPE;
                   8948:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   8949:          ncovf++; /* Varying variables without age */
                   8950:          TvarF[ncovf]=Tvar[k];
                   8951:          TvarFind[ncovf]=k;
                   8952:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8953:          Fixed[k]= 1;
                   8954:          Dummy[k]= 0;
                   8955:          modell[k].maintype= VTYPE;
                   8956:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   8957:          ncovv++; /* Varying variables without age */
                   8958:          TvarV[ncovv]=Tvar[k];
                   8959:          TvarVind[ncovv]=k;
                   8960:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8961:          Fixed[k]= 1;
                   8962:          Dummy[k]= 1;
                   8963:          modell[k].maintype= VTYPE;
                   8964:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   8965:          ncovv++; /* Varying variables without age */
                   8966:          TvarV[ncovv]=Tvar[k];
                   8967:          TvarVind[ncovv]=k;
                   8968:        }
1.227     brouard  8969:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  8970:        if(Tvard[k1][2] <=ncovcol){
                   8971:          Fixed[k]= 0;  /* or 2 ?*/
                   8972:          Dummy[k]= 1;
                   8973:          modell[k].maintype= FTYPE;
                   8974:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   8975:          ncovf++; /* Fixed variables without age */
                   8976:          TvarF[ncovf]=Tvar[k];
                   8977:          TvarFind[ncovf]=k;
                   8978:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   8979:          Fixed[k]= 1;
                   8980:          Dummy[k]= 1;
                   8981:          modell[k].maintype= VTYPE;
                   8982:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   8983:          ncovv++; /* Varying variables without age */
                   8984:          TvarV[ncovv]=Tvar[k];
                   8985:          TvarVind[ncovv]=k;
                   8986:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   8987:          Fixed[k]= 1;
                   8988:          Dummy[k]= 1;
                   8989:          modell[k].maintype= VTYPE;
                   8990:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   8991:          ncovv++; /* Varying variables without age */
                   8992:          TvarV[ncovv]=Tvar[k];
                   8993:          TvarVind[ncovv]=k;
                   8994:          ncovv++; /* Varying variables without age */
                   8995:          TvarV[ncovv]=Tvar[k];
                   8996:          TvarVind[ncovv]=k;
                   8997:        }
1.227     brouard  8998:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  8999:        if(Tvard[k1][2] <=ncovcol){
                   9000:          Fixed[k]= 1;
                   9001:          Dummy[k]= 1;
                   9002:          modell[k].maintype= VTYPE;
                   9003:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9004:          ncovv++; /* Varying variables without age */
                   9005:          TvarV[ncovv]=Tvar[k];
                   9006:          TvarVind[ncovv]=k;
                   9007:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9008:          Fixed[k]= 1;
                   9009:          Dummy[k]= 1;
                   9010:          modell[k].maintype= VTYPE;
                   9011:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9012:          ncovv++; /* Varying variables without age */
                   9013:          TvarV[ncovv]=Tvar[k];
                   9014:          TvarVind[ncovv]=k;
                   9015:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9016:          Fixed[k]= 1;
                   9017:          Dummy[k]= 0;
                   9018:          modell[k].maintype= VTYPE;
                   9019:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9020:          ncovv++; /* Varying variables without age */
                   9021:          TvarV[ncovv]=Tvar[k];
                   9022:          TvarVind[ncovv]=k;
                   9023:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9024:          Fixed[k]= 1;
                   9025:          Dummy[k]= 1;
                   9026:          modell[k].maintype= VTYPE;
                   9027:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9028:          ncovv++; /* Varying variables without age */
                   9029:          TvarV[ncovv]=Tvar[k];
                   9030:          TvarVind[ncovv]=k;
                   9031:        }
1.227     brouard  9032:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9033:        if(Tvard[k1][2] <=ncovcol){
                   9034:          Fixed[k]= 1;
                   9035:          Dummy[k]= 1;
                   9036:          modell[k].maintype= VTYPE;
                   9037:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9038:          ncovv++; /* Varying variables without age */
                   9039:          TvarV[ncovv]=Tvar[k];
                   9040:          TvarVind[ncovv]=k;
                   9041:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9042:          Fixed[k]= 1;
                   9043:          Dummy[k]= 1;
                   9044:          modell[k].maintype= VTYPE;
                   9045:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9046:          ncovv++; /* Varying variables without age */
                   9047:          TvarV[ncovv]=Tvar[k];
                   9048:          TvarVind[ncovv]=k;
                   9049:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9050:          Fixed[k]= 1;
                   9051:          Dummy[k]= 1;
                   9052:          modell[k].maintype= VTYPE;
                   9053:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9054:          ncovv++; /* Varying variables without age */
                   9055:          TvarV[ncovv]=Tvar[k];
                   9056:          TvarVind[ncovv]=k;
                   9057:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9058:          Fixed[k]= 1;
                   9059:          Dummy[k]= 1;
                   9060:          modell[k].maintype= VTYPE;
                   9061:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9062:          ncovv++; /* Varying variables without age */
                   9063:          TvarV[ncovv]=Tvar[k];
                   9064:          TvarVind[ncovv]=k;
                   9065:        }
1.227     brouard  9066:       }else{
1.240     brouard  9067:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9068:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9069:       } /*end k1*/
1.225     brouard  9070:     }else{
1.226     brouard  9071:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9072:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9073:     }
1.227     brouard  9074:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9075:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9076:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9077:   }
                   9078:   /* Searching for doublons in the model */
                   9079:   for(k1=1; k1<= cptcovt;k1++){
                   9080:     for(k2=1; k2 <k1;k2++){
                   9081:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9082:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9083:          if(Tvar[k1]==Tvar[k2]){
                   9084:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9085:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9086:            return(1);
                   9087:          }
                   9088:        }else if (Typevar[k1] ==2){
                   9089:          k3=Tposprod[k1];
                   9090:          k4=Tposprod[k2];
                   9091:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9092:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9093:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9094:            return(1);
                   9095:          }
                   9096:        }
1.227     brouard  9097:       }
                   9098:     }
1.225     brouard  9099:   }
                   9100:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9101:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9102:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9103:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9104:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9105:   /*endread:*/
1.225     brouard  9106:   printf("Exiting decodemodel: ");
                   9107:   return (1);
1.136     brouard  9108: }
                   9109: 
1.169     brouard  9110: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9111: {/* Check ages at death */
1.136     brouard  9112:   int i, m;
1.218     brouard  9113:   int firstone=0;
                   9114:   
1.136     brouard  9115:   for (i=1; i<=imx; i++) {
                   9116:     for(m=2; (m<= maxwav); m++) {
                   9117:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9118:        anint[m][i]=9999;
1.216     brouard  9119:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9120:          s[m][i]=-1;
1.136     brouard  9121:       }
                   9122:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9123:        *nberr = *nberr + 1;
1.218     brouard  9124:        if(firstone == 0){
                   9125:          firstone=1;
1.260     brouard  9126:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9127:        }
1.262     brouard  9128:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9129:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9130:       }
                   9131:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9132:        (*nberr)++;
1.259     brouard  9133:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9134:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9135:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9136:       }
                   9137:     }
                   9138:   }
                   9139: 
                   9140:   for (i=1; i<=imx; i++)  {
                   9141:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9142:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9143:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9144:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9145:          if(agedc[i]>0){
                   9146:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9147:              agev[m][i]=agedc[i];
1.214     brouard  9148:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9149:            }else {
1.136     brouard  9150:              if ((int)andc[i]!=9999){
                   9151:                nbwarn++;
                   9152:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9153:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9154:                agev[m][i]=-1;
                   9155:              }
                   9156:            }
1.169     brouard  9157:          } /* agedc > 0 */
1.214     brouard  9158:        } /* end if */
1.136     brouard  9159:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9160:                                 years but with the precision of a month */
                   9161:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9162:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9163:            agev[m][i]=1;
                   9164:          else if(agev[m][i] < *agemin){ 
                   9165:            *agemin=agev[m][i];
                   9166:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9167:          }
                   9168:          else if(agev[m][i] >*agemax){
                   9169:            *agemax=agev[m][i];
1.156     brouard  9170:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9171:          }
                   9172:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9173:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9174:        } /* en if 9*/
1.136     brouard  9175:        else { /* =9 */
1.214     brouard  9176:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9177:          agev[m][i]=1;
                   9178:          s[m][i]=-1;
                   9179:        }
                   9180:       }
1.214     brouard  9181:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9182:        agev[m][i]=1;
1.214     brouard  9183:       else{
                   9184:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9185:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9186:        agev[m][i]=0;
                   9187:       }
                   9188:     } /* End for lastpass */
                   9189:   }
1.136     brouard  9190:     
                   9191:   for (i=1; i<=imx; i++)  {
                   9192:     for(m=firstpass; (m<=lastpass); m++){
                   9193:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9194:        (*nberr)++;
1.136     brouard  9195:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9196:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9197:        return 1;
                   9198:       }
                   9199:     }
                   9200:   }
                   9201: 
                   9202:   /*for (i=1; i<=imx; i++){
                   9203:   for (m=firstpass; (m<lastpass); m++){
                   9204:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9205: }
                   9206: 
                   9207: }*/
                   9208: 
                   9209: 
1.139     brouard  9210:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9211:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9212: 
                   9213:   return (0);
1.164     brouard  9214:  /* endread:*/
1.136     brouard  9215:     printf("Exiting calandcheckages: ");
                   9216:     return (1);
                   9217: }
                   9218: 
1.172     brouard  9219: #if defined(_MSC_VER)
                   9220: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9221: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9222: //#include "stdafx.h"
                   9223: //#include <stdio.h>
                   9224: //#include <tchar.h>
                   9225: //#include <windows.h>
                   9226: //#include <iostream>
                   9227: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9228: 
                   9229: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9230: 
                   9231: BOOL IsWow64()
                   9232: {
                   9233:        BOOL bIsWow64 = FALSE;
                   9234: 
                   9235:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9236:        //  (HANDLE, PBOOL);
                   9237: 
                   9238:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9239: 
                   9240:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9241:        const char funcName[] = "IsWow64Process";
                   9242:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9243:                GetProcAddress(module, funcName);
                   9244: 
                   9245:        if (NULL != fnIsWow64Process)
                   9246:        {
                   9247:                if (!fnIsWow64Process(GetCurrentProcess(),
                   9248:                        &bIsWow64))
                   9249:                        //throw std::exception("Unknown error");
                   9250:                        printf("Unknown error\n");
                   9251:        }
                   9252:        return bIsWow64 != FALSE;
                   9253: }
                   9254: #endif
1.177     brouard  9255: 
1.191     brouard  9256: void syscompilerinfo(int logged)
1.167     brouard  9257:  {
                   9258:    /* #include "syscompilerinfo.h"*/
1.185     brouard  9259:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   9260:    /* /GS /W3 /Gy
                   9261:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   9262:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   9263:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  9264:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   9265:    */ 
                   9266:    /* 64 bits */
1.185     brouard  9267:    /*
                   9268:      /GS /W3 /Gy
                   9269:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   9270:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   9271:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   9272:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   9273:    /* Optimization are useless and O3 is slower than O2 */
                   9274:    /*
                   9275:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   9276:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   9277:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   9278:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   9279:    */
1.186     brouard  9280:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  9281:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   9282:       /PDB:"visual studio
                   9283:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   9284:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   9285:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   9286:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   9287:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   9288:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   9289:       uiAccess='false'"
                   9290:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   9291:       /NOLOGO /TLBID:1
                   9292:    */
1.177     brouard  9293: #if defined __INTEL_COMPILER
1.178     brouard  9294: #if defined(__GNUC__)
                   9295:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   9296: #endif
1.177     brouard  9297: #elif defined(__GNUC__) 
1.179     brouard  9298: #ifndef  __APPLE__
1.174     brouard  9299: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  9300: #endif
1.177     brouard  9301:    struct utsname sysInfo;
1.178     brouard  9302:    int cross = CROSS;
                   9303:    if (cross){
                   9304:           printf("Cross-");
1.191     brouard  9305:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  9306:    }
1.174     brouard  9307: #endif
                   9308: 
1.171     brouard  9309: #include <stdint.h>
1.178     brouard  9310: 
1.191     brouard  9311:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  9312: #if defined(__clang__)
1.191     brouard  9313:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  9314: #endif
                   9315: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  9316:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  9317: #endif
                   9318: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  9319:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  9320: #endif
                   9321: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  9322:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  9323: #endif
                   9324: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  9325:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  9326: #endif
                   9327: #if defined(_MSC_VER)
1.191     brouard  9328:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  9329: #endif
                   9330: #if defined(__PGI)
1.191     brouard  9331:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  9332: #endif
                   9333: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  9334:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  9335: #endif
1.191     brouard  9336:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  9337:    
1.167     brouard  9338: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   9339: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   9340:     // Windows (x64 and x86)
1.191     brouard  9341:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  9342: #elif __unix__ // all unices, not all compilers
                   9343:     // Unix
1.191     brouard  9344:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  9345: #elif __linux__
                   9346:     // linux
1.191     brouard  9347:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  9348: #elif __APPLE__
1.174     brouard  9349:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  9350:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  9351: #endif
                   9352: 
                   9353: /*  __MINGW32__          */
                   9354: /*  __CYGWIN__  */
                   9355: /* __MINGW64__  */
                   9356: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   9357: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   9358: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   9359: /* _WIN64  // Defined for applications for Win64. */
                   9360: /* _M_X64 // Defined for compilations that target x64 processors. */
                   9361: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  9362: 
1.167     brouard  9363: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  9364:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  9365: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  9366:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  9367: #else
1.191     brouard  9368:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  9369: #endif
                   9370: 
1.169     brouard  9371: #if defined(__GNUC__)
                   9372: # if defined(__GNUC_PATCHLEVEL__)
                   9373: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9374:                             + __GNUC_MINOR__ * 100 \
                   9375:                             + __GNUC_PATCHLEVEL__)
                   9376: # else
                   9377: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   9378:                             + __GNUC_MINOR__ * 100)
                   9379: # endif
1.174     brouard  9380:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  9381:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  9382: 
                   9383:    if (uname(&sysInfo) != -1) {
                   9384:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  9385:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  9386:    }
                   9387:    else
                   9388:       perror("uname() error");
1.179     brouard  9389:    //#ifndef __INTEL_COMPILER 
                   9390: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  9391:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  9392:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  9393: #endif
1.169     brouard  9394: #endif
1.172     brouard  9395: 
                   9396:    //   void main()
                   9397:    //   {
1.169     brouard  9398: #if defined(_MSC_VER)
1.174     brouard  9399:    if (IsWow64()){
1.191     brouard  9400:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   9401:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  9402:    }
                   9403:    else{
1.191     brouard  9404:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   9405:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  9406:    }
1.172     brouard  9407:    //     printf("\nPress Enter to continue...");
                   9408:    //     getchar();
                   9409:    //   }
                   9410: 
1.169     brouard  9411: #endif
                   9412:    
1.167     brouard  9413: 
1.219     brouard  9414: }
1.136     brouard  9415: 
1.219     brouard  9416: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  9417:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  9418:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  9419:   /* double ftolpl = 1.e-10; */
1.180     brouard  9420:   double age, agebase, agelim;
1.203     brouard  9421:   double tot;
1.180     brouard  9422: 
1.202     brouard  9423:   strcpy(filerespl,"PL_");
                   9424:   strcat(filerespl,fileresu);
                   9425:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   9426:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9427:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   9428:   }
1.227     brouard  9429:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   9430:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  9431:   pstamp(ficrespl);
1.203     brouard  9432:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  9433:   fprintf(ficrespl,"#Age ");
                   9434:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   9435:   fprintf(ficrespl,"\n");
1.180     brouard  9436:   
1.219     brouard  9437:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  9438: 
1.219     brouard  9439:   agebase=ageminpar;
                   9440:   agelim=agemaxpar;
1.180     brouard  9441: 
1.227     brouard  9442:   /* i1=pow(2,ncoveff); */
1.234     brouard  9443:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  9444:   if (cptcovn < 1){i1=1;}
1.180     brouard  9445: 
1.238     brouard  9446:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   9447:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  9448:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9449:        continue;
1.235     brouard  9450: 
1.238     brouard  9451:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9452:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   9453:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   9454:       /* k=k+1; */
                   9455:       /* to clean */
                   9456:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9457:       fprintf(ficrespl,"#******");
                   9458:       printf("#******");
                   9459:       fprintf(ficlog,"#******");
                   9460:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9461:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   9462:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9463:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9464:       }
                   9465:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9466:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9467:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9468:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9469:       }
                   9470:       fprintf(ficrespl,"******\n");
                   9471:       printf("******\n");
                   9472:       fprintf(ficlog,"******\n");
                   9473:       if(invalidvarcomb[k]){
                   9474:        printf("\nCombination (%d) ignored because no case \n",k); 
                   9475:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   9476:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   9477:        continue;
                   9478:       }
1.219     brouard  9479: 
1.238     brouard  9480:       fprintf(ficrespl,"#Age ");
                   9481:       for(j=1;j<=cptcoveff;j++) {
                   9482:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9483:       }
                   9484:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   9485:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  9486:     
1.238     brouard  9487:       for (age=agebase; age<=agelim; age++){
                   9488:        /* for (age=agebase; age<=agebase; age++){ */
                   9489:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   9490:        fprintf(ficrespl,"%.0f ",age );
                   9491:        for(j=1;j<=cptcoveff;j++)
                   9492:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9493:        tot=0.;
                   9494:        for(i=1; i<=nlstate;i++){
                   9495:          tot +=  prlim[i][i];
                   9496:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   9497:        }
                   9498:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   9499:       } /* Age */
                   9500:       /* was end of cptcod */
                   9501:     } /* cptcov */
                   9502:   } /* nres */
1.219     brouard  9503:   return 0;
1.180     brouard  9504: }
                   9505: 
1.218     brouard  9506: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   9507:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   9508:        
                   9509:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   9510:    * at any age between ageminpar and agemaxpar
                   9511:         */
1.235     brouard  9512:   int i, j, k, i1, nres=0 ;
1.217     brouard  9513:   /* double ftolpl = 1.e-10; */
                   9514:   double age, agebase, agelim;
                   9515:   double tot;
1.218     brouard  9516:   /* double ***mobaverage; */
                   9517:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  9518: 
                   9519:   strcpy(fileresplb,"PLB_");
                   9520:   strcat(fileresplb,fileresu);
                   9521:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   9522:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9523:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   9524:   }
                   9525:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9526:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   9527:   pstamp(ficresplb);
                   9528:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   9529:   fprintf(ficresplb,"#Age ");
                   9530:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   9531:   fprintf(ficresplb,"\n");
                   9532:   
1.218     brouard  9533:   
                   9534:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   9535:   
                   9536:   agebase=ageminpar;
                   9537:   agelim=agemaxpar;
                   9538:   
                   9539:   
1.227     brouard  9540:   i1=pow(2,cptcoveff);
1.218     brouard  9541:   if (cptcovn < 1){i1=1;}
1.227     brouard  9542:   
1.238     brouard  9543:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9544:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9545:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9546:        continue;
                   9547:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   9548:       fprintf(ficresplb,"#******");
                   9549:       printf("#******");
                   9550:       fprintf(ficlog,"#******");
                   9551:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   9552:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9553:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9554:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9555:       }
                   9556:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9557:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9558:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9559:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9560:       }
                   9561:       fprintf(ficresplb,"******\n");
                   9562:       printf("******\n");
                   9563:       fprintf(ficlog,"******\n");
                   9564:       if(invalidvarcomb[k]){
                   9565:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   9566:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   9567:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   9568:        continue;
                   9569:       }
1.218     brouard  9570:     
1.238     brouard  9571:       fprintf(ficresplb,"#Age ");
                   9572:       for(j=1;j<=cptcoveff;j++) {
                   9573:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9574:       }
                   9575:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   9576:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  9577:     
                   9578:     
1.238     brouard  9579:       for (age=agebase; age<=agelim; age++){
                   9580:        /* for (age=agebase; age<=agebase; age++){ */
                   9581:        if(mobilavproj > 0){
                   9582:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   9583:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9584:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  9585:        }else if (mobilavproj == 0){
                   9586:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9587:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   9588:          exit(1);
                   9589:        }else{
                   9590:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  9591:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.238     brouard  9592:        }
                   9593:        fprintf(ficresplb,"%.0f ",age );
                   9594:        for(j=1;j<=cptcoveff;j++)
                   9595:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9596:        tot=0.;
                   9597:        for(i=1; i<=nlstate;i++){
                   9598:          tot +=  bprlim[i][i];
                   9599:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   9600:        }
                   9601:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   9602:       } /* Age */
                   9603:       /* was end of cptcod */
1.255     brouard  9604:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  9605:     } /* end of any combination */
                   9606:   } /* end of nres */  
1.218     brouard  9607:   /* hBijx(p, bage, fage); */
                   9608:   /* fclose(ficrespijb); */
                   9609:   
                   9610:   return 0;
1.217     brouard  9611: }
1.218     brouard  9612:  
1.180     brouard  9613: int hPijx(double *p, int bage, int fage){
                   9614:     /*------------- h Pij x at various ages ------------*/
                   9615: 
                   9616:   int stepsize;
                   9617:   int agelim;
                   9618:   int hstepm;
                   9619:   int nhstepm;
1.235     brouard  9620:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  9621: 
                   9622:   double agedeb;
                   9623:   double ***p3mat;
                   9624: 
1.201     brouard  9625:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  9626:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   9627:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9628:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   9629:     }
                   9630:     printf("Computing pij: result on file '%s' \n", filerespij);
                   9631:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   9632:   
                   9633:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9634:     /*if (stepm<=24) stepsize=2;*/
                   9635: 
                   9636:     agelim=AGESUP;
                   9637:     hstepm=stepsize*YEARM; /* Every year of age */
                   9638:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  9639:                
1.180     brouard  9640:     /* hstepm=1;   aff par mois*/
                   9641:     pstamp(ficrespij);
                   9642:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  9643:     i1= pow(2,cptcoveff);
1.218     brouard  9644:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9645:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9646:                /*      k=k+1;  */
1.235     brouard  9647:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   9648:     for(k=1; k<=i1;k++){
1.253     brouard  9649:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  9650:        continue;
1.183     brouard  9651:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  9652:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  9653:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  9654:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   9655:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9656:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   9657:       }
1.183     brouard  9658:       fprintf(ficrespij,"******\n");
                   9659:       
                   9660:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   9661:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   9662:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   9663:        
                   9664:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  9665:        
1.183     brouard  9666:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9667:        oldm=oldms;savm=savms;
1.235     brouard  9668:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  9669:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   9670:        for(i=1; i<=nlstate;i++)
                   9671:          for(j=1; j<=nlstate+ndeath;j++)
                   9672:            fprintf(ficrespij," %1d-%1d",i,j);
                   9673:        fprintf(ficrespij,"\n");
                   9674:        for (h=0; h<=nhstepm; h++){
                   9675:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9676:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  9677:          for(i=1; i<=nlstate;i++)
                   9678:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  9679:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  9680:          fprintf(ficrespij,"\n");
                   9681:        }
1.183     brouard  9682:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9683:        fprintf(ficrespij,"\n");
                   9684:       }
1.180     brouard  9685:       /*}*/
                   9686:     }
1.218     brouard  9687:     return 0;
1.180     brouard  9688: }
1.218     brouard  9689:  
                   9690:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  9691:     /*------------- h Bij x at various ages ------------*/
                   9692: 
                   9693:   int stepsize;
1.218     brouard  9694:   /* int agelim; */
                   9695:        int ageminl;
1.217     brouard  9696:   int hstepm;
                   9697:   int nhstepm;
1.238     brouard  9698:   int h, i, i1, j, k, nres;
1.218     brouard  9699:        
1.217     brouard  9700:   double agedeb;
                   9701:   double ***p3mat;
1.218     brouard  9702:        
                   9703:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   9704:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   9705:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9706:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   9707:   }
                   9708:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   9709:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   9710:   
                   9711:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   9712:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  9713:   
1.218     brouard  9714:   /* agelim=AGESUP; */
                   9715:   ageminl=30;
                   9716:   hstepm=stepsize*YEARM; /* Every year of age */
                   9717:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   9718:   
                   9719:   /* hstepm=1;   aff par mois*/
                   9720:   pstamp(ficrespijb);
1.255     brouard  9721:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  9722:   i1= pow(2,cptcoveff);
1.218     brouard  9723:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   9724:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   9725:   /*   k=k+1;  */
1.238     brouard  9726:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   9727:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  9728:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  9729:        continue;
                   9730:       fprintf(ficrespijb,"\n#****** ");
                   9731:       for(j=1;j<=cptcoveff;j++)
                   9732:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   9733:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   9734:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   9735:       }
                   9736:       fprintf(ficrespijb,"******\n");
                   9737:       if(invalidvarcomb[k]){
                   9738:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   9739:        continue;
                   9740:       }
                   9741:       
                   9742:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   9743:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   9744:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   9745:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   9746:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   9747:        
                   9748:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   9749:        
                   9750:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9751:        /* oldm=oldms;savm=savms; */
                   9752:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   9753:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k);
                   9754:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  9755:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  9756:        for(i=1; i<=nlstate;i++)
                   9757:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  9758:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  9759:        fprintf(ficrespijb,"\n");
1.238     brouard  9760:        for (h=0; h<=nhstepm; h++){
                   9761:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   9762:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   9763:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   9764:          for(i=1; i<=nlstate;i++)
                   9765:            for(j=1; j<=nlstate+ndeath;j++)
                   9766:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   9767:          fprintf(ficrespijb,"\n");
                   9768:        }
                   9769:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   9770:        fprintf(ficrespijb,"\n");
                   9771:       } /* end age deb */
                   9772:     } /* end combination */
                   9773:   } /* end nres */
1.218     brouard  9774:   return 0;
                   9775:  } /*  hBijx */
1.217     brouard  9776: 
1.180     brouard  9777: 
1.136     brouard  9778: /***********************************************/
                   9779: /**************** Main Program *****************/
                   9780: /***********************************************/
                   9781: 
                   9782: int main(int argc, char *argv[])
                   9783: {
                   9784: #ifdef GSL
                   9785:   const gsl_multimin_fminimizer_type *T;
                   9786:   size_t iteri = 0, it;
                   9787:   int rval = GSL_CONTINUE;
                   9788:   int status = GSL_SUCCESS;
                   9789:   double ssval;
                   9790: #endif
                   9791:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  9792:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  9793:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  9794:   int jj, ll, li, lj, lk;
1.136     brouard  9795:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  9796:   int num_filled;
1.136     brouard  9797:   int itimes;
                   9798:   int NDIM=2;
                   9799:   int vpopbased=0;
1.235     brouard  9800:   int nres=0;
1.258     brouard  9801:   int endishere=0;
1.136     brouard  9802: 
1.164     brouard  9803:   char ca[32], cb[32];
1.136     brouard  9804:   /*  FILE *fichtm; *//* Html File */
                   9805:   /* FILE *ficgp;*/ /*Gnuplot File */
                   9806:   struct stat info;
1.191     brouard  9807:   double agedeb=0.;
1.194     brouard  9808: 
                   9809:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  9810:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  9811: 
1.165     brouard  9812:   double fret;
1.191     brouard  9813:   double dum=0.; /* Dummy variable */
1.136     brouard  9814:   double ***p3mat;
1.218     brouard  9815:   /* double ***mobaverage; */
1.164     brouard  9816: 
                   9817:   char line[MAXLINE];
1.197     brouard  9818:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   9819: 
1.234     brouard  9820:   char  modeltemp[MAXLINE];
1.230     brouard  9821:   char resultline[MAXLINE];
                   9822:   
1.136     brouard  9823:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  9824:   char *tok, *val; /* pathtot */
1.136     brouard  9825:   int firstobs=1, lastobs=10;
1.195     brouard  9826:   int c,  h , cpt, c2;
1.191     brouard  9827:   int jl=0;
                   9828:   int i1, j1, jk, stepsize=0;
1.194     brouard  9829:   int count=0;
                   9830: 
1.164     brouard  9831:   int *tab; 
1.136     brouard  9832:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  9833:   int backcast=0;
1.136     brouard  9834:   int mobilav=0,popforecast=0;
1.191     brouard  9835:   int hstepm=0, nhstepm=0;
1.136     brouard  9836:   int agemortsup;
                   9837:   float  sumlpop=0.;
                   9838:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   9839:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   9840: 
1.191     brouard  9841:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  9842:   double ftolpl=FTOL;
                   9843:   double **prlim;
1.217     brouard  9844:   double **bprlim;
1.136     brouard  9845:   double ***param; /* Matrix of parameters */
1.251     brouard  9846:   double ***paramstart; /* Matrix of starting parameter values */
                   9847:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  9848:   double **matcov; /* Matrix of covariance */
1.203     brouard  9849:   double **hess; /* Hessian matrix */
1.136     brouard  9850:   double ***delti3; /* Scale */
                   9851:   double *delti; /* Scale */
                   9852:   double ***eij, ***vareij;
                   9853:   double **varpl; /* Variances of prevalence limits by age */
                   9854:   double *epj, vepp;
1.164     brouard  9855: 
1.136     brouard  9856:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  9857:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   9858: 
1.136     brouard  9859:   double **ximort;
1.145     brouard  9860:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  9861:   int *dcwave;
                   9862: 
1.164     brouard  9863:   char z[1]="c";
1.136     brouard  9864: 
                   9865:   /*char  *strt;*/
                   9866:   char strtend[80];
1.126     brouard  9867: 
1.164     brouard  9868: 
1.126     brouard  9869: /*   setlocale (LC_ALL, ""); */
                   9870: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   9871: /*   textdomain (PACKAGE); */
                   9872: /*   setlocale (LC_CTYPE, ""); */
                   9873: /*   setlocale (LC_MESSAGES, ""); */
                   9874: 
                   9875:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  9876:   rstart_time = time(NULL);  
                   9877:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   9878:   start_time = *localtime(&rstart_time);
1.126     brouard  9879:   curr_time=start_time;
1.157     brouard  9880:   /*tml = *localtime(&start_time.tm_sec);*/
                   9881:   /* strcpy(strstart,asctime(&tml)); */
                   9882:   strcpy(strstart,asctime(&start_time));
1.126     brouard  9883: 
                   9884: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  9885: /*  tp.tm_sec = tp.tm_sec +86400; */
                   9886: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  9887: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   9888: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   9889: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  9890: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  9891: /*   strt=asctime(&tmg); */
                   9892: /*   printf("Time(after) =%s",strstart);  */
                   9893: /*  (void) time (&time_value);
                   9894: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   9895: *  tm = *localtime(&time_value);
                   9896: *  strstart=asctime(&tm);
                   9897: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   9898: */
                   9899: 
                   9900:   nberr=0; /* Number of errors and warnings */
                   9901:   nbwarn=0;
1.184     brouard  9902: #ifdef WIN32
                   9903:   _getcwd(pathcd, size);
                   9904: #else
1.126     brouard  9905:   getcwd(pathcd, size);
1.184     brouard  9906: #endif
1.191     brouard  9907:   syscompilerinfo(0);
1.196     brouard  9908:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  9909:   if(argc <=1){
                   9910:     printf("\nEnter the parameter file name: ");
1.205     brouard  9911:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   9912:       printf("ERROR Empty parameter file name\n");
                   9913:       goto end;
                   9914:     }
1.126     brouard  9915:     i=strlen(pathr);
                   9916:     if(pathr[i-1]=='\n')
                   9917:       pathr[i-1]='\0';
1.156     brouard  9918:     i=strlen(pathr);
1.205     brouard  9919:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  9920:       pathr[i-1]='\0';
1.205     brouard  9921:     }
                   9922:     i=strlen(pathr);
                   9923:     if( i==0 ){
                   9924:       printf("ERROR Empty parameter file name\n");
                   9925:       goto end;
                   9926:     }
                   9927:     for (tok = pathr; tok != NULL; ){
1.126     brouard  9928:       printf("Pathr |%s|\n",pathr);
                   9929:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   9930:       printf("val= |%s| pathr=%s\n",val,pathr);
                   9931:       strcpy (pathtot, val);
                   9932:       if(pathr[0] == '\0') break; /* Dirty */
                   9933:     }
                   9934:   }
                   9935:   else{
                   9936:     strcpy(pathtot,argv[1]);
                   9937:   }
                   9938:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   9939:   /*cygwin_split_path(pathtot,path,optionfile);
                   9940:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   9941:   /* cutv(path,optionfile,pathtot,'\\');*/
                   9942: 
                   9943:   /* Split argv[0], imach program to get pathimach */
                   9944:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   9945:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9946:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   9947:  /*   strcpy(pathimach,argv[0]); */
                   9948:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   9949:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   9950:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  9951: #ifdef WIN32
                   9952:   _chdir(path); /* Can be a relative path */
                   9953:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   9954: #else
1.126     brouard  9955:   chdir(path); /* Can be a relative path */
1.184     brouard  9956:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   9957: #endif
                   9958:   printf("Current directory %s!\n",pathcd);
1.126     brouard  9959:   strcpy(command,"mkdir ");
                   9960:   strcat(command,optionfilefiname);
                   9961:   if((outcmd=system(command)) != 0){
1.169     brouard  9962:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  9963:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   9964:     /* fclose(ficlog); */
                   9965: /*     exit(1); */
                   9966:   }
                   9967: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   9968: /*     perror("mkdir"); */
                   9969: /*   } */
                   9970: 
                   9971:   /*-------- arguments in the command line --------*/
                   9972: 
1.186     brouard  9973:   /* Main Log file */
1.126     brouard  9974:   strcat(filelog, optionfilefiname);
                   9975:   strcat(filelog,".log");    /* */
                   9976:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   9977:     printf("Problem with logfile %s\n",filelog);
                   9978:     goto end;
                   9979:   }
                   9980:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  9981:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  9982:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   9983:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   9984:  path=%s \n\
                   9985:  optionfile=%s\n\
                   9986:  optionfilext=%s\n\
1.156     brouard  9987:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  9988: 
1.197     brouard  9989:   syscompilerinfo(1);
1.167     brouard  9990: 
1.126     brouard  9991:   printf("Local time (at start):%s",strstart);
                   9992:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   9993:   fflush(ficlog);
                   9994: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  9995: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  9996: 
                   9997:   /* */
                   9998:   strcpy(fileres,"r");
                   9999:   strcat(fileres, optionfilefiname);
1.201     brouard  10000:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10001:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10002:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10003: 
1.186     brouard  10004:   /* Main ---------arguments file --------*/
1.126     brouard  10005: 
                   10006:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10007:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10008:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10009:     fflush(ficlog);
1.149     brouard  10010:     /* goto end; */
                   10011:     exit(70); 
1.126     brouard  10012:   }
                   10013: 
                   10014: 
                   10015: 
                   10016:   strcpy(filereso,"o");
1.201     brouard  10017:   strcat(filereso,fileresu);
1.126     brouard  10018:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10019:     printf("Problem with Output resultfile: %s\n", filereso);
                   10020:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10021:     fflush(ficlog);
                   10022:     goto end;
                   10023:   }
                   10024: 
                   10025:   /* Reads comments: lines beginning with '#' */
                   10026:   numlinepar=0;
1.197     brouard  10027: 
                   10028:     /* First parameter line */
                   10029:   while(fgets(line, MAXLINE, ficpar)) {
                   10030:     /* If line starts with a # it is a comment */
                   10031:     if (line[0] == '#') {
                   10032:       numlinepar++;
                   10033:       fputs(line,stdout);
                   10034:       fputs(line,ficparo);
                   10035:       fputs(line,ficlog);
                   10036:       continue;
                   10037:     }else
                   10038:       break;
                   10039:   }
                   10040:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10041:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10042:     if (num_filled != 5) {
                   10043:       printf("Should be 5 parameters\n");
                   10044:     }
1.126     brouard  10045:     numlinepar++;
1.197     brouard  10046:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10047:   }
                   10048:   /* Second parameter line */
                   10049:   while(fgets(line, MAXLINE, ficpar)) {
                   10050:     /* If line starts with a # it is a comment */
                   10051:     if (line[0] == '#') {
                   10052:       numlinepar++;
                   10053:       fputs(line,stdout);
                   10054:       fputs(line,ficparo);
                   10055:       fputs(line,ficlog);
                   10056:       continue;
                   10057:     }else
                   10058:       break;
                   10059:   }
1.223     brouard  10060:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10061:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10062:     if (num_filled != 11) {
                   10063:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10064:       printf("but line=%s\n",line);
1.197     brouard  10065:     }
1.223     brouard  10066:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10067:   }
1.203     brouard  10068:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10069:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10070:   /* Third parameter line */
                   10071:   while(fgets(line, MAXLINE, ficpar)) {
                   10072:     /* If line starts with a # it is a comment */
                   10073:     if (line[0] == '#') {
                   10074:       numlinepar++;
                   10075:       fputs(line,stdout);
                   10076:       fputs(line,ficparo);
                   10077:       fputs(line,ficlog);
                   10078:       continue;
                   10079:     }else
                   10080:       break;
                   10081:   }
1.201     brouard  10082:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263   ! brouard  10083:     if (num_filled == 0){
        !          10084:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
        !          10085:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
        !          10086:       model[0]='\0';
        !          10087:       goto end;
        !          10088:     } else if (num_filled != 1){
1.197     brouard  10089:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10090:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10091:       model[0]='\0';
                   10092:       goto end;
                   10093:     }
                   10094:     else{
                   10095:       if (model[0]=='+'){
                   10096:        for(i=1; i<=strlen(model);i++)
                   10097:          modeltemp[i-1]=model[i];
1.201     brouard  10098:        strcpy(model,modeltemp); 
1.197     brouard  10099:       }
                   10100:     }
1.199     brouard  10101:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10102:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10103:   }
                   10104:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10105:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10106:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10107:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10108:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10109:   fflush(ficlog);
1.190     brouard  10110:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10111:   if(model[0]=='#'){
1.187     brouard  10112:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10113:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10114:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10115:     if(mle != -1){
                   10116:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10117:       exit(1);
                   10118:     }
                   10119:   }
1.126     brouard  10120:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10121:     ungetc(c,ficpar);
                   10122:     fgets(line, MAXLINE, ficpar);
                   10123:     numlinepar++;
1.195     brouard  10124:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10125:       z[0]=line[1];
                   10126:     }
                   10127:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10128:     fputs(line, stdout);
                   10129:     //puts(line);
1.126     brouard  10130:     fputs(line,ficparo);
                   10131:     fputs(line,ficlog);
                   10132:   }
                   10133:   ungetc(c,ficpar);
                   10134: 
                   10135:    
1.145     brouard  10136:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.225     brouard  10137:   coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
1.233     brouard  10138:   cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.225     brouard  10139:   cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
1.136     brouard  10140:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10141:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10142:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10143:   */
                   10144:   if (strlen(model)>1) 
1.187     brouard  10145:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10146:   else
1.187     brouard  10147:     ncovmodel=2; /* Constant and age */
1.133     brouard  10148:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10149:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10150:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10151:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10152:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10153:     fflush(stdout);
                   10154:     fclose (ficlog);
                   10155:     goto end;
                   10156:   }
1.126     brouard  10157:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10158:   delti=delti3[1][1];
                   10159:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10160:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10161: /* We could also provide initial parameters values giving by simple logistic regression 
                   10162:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10163:       /* for(i=1;i<nlstate;i++){ */
                   10164:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10165:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10166:       /* } */
1.126     brouard  10167:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10168:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10169:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10170:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10171:     fclose (ficparo);
                   10172:     fclose (ficlog);
                   10173:     goto end;
                   10174:     exit(0);
1.220     brouard  10175:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10176:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10177:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10178:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10179:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10180:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10181:     hess=matrix(1,npar,1,npar);
1.220     brouard  10182:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10183:     /* Read guessed parameters */
1.126     brouard  10184:     /* Reads comments: lines beginning with '#' */
                   10185:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10186:       ungetc(c,ficpar);
                   10187:       fgets(line, MAXLINE, ficpar);
                   10188:       numlinepar++;
1.141     brouard  10189:       fputs(line,stdout);
1.126     brouard  10190:       fputs(line,ficparo);
                   10191:       fputs(line,ficlog);
                   10192:     }
                   10193:     ungetc(c,ficpar);
                   10194:     
                   10195:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10196:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10197:     for(i=1; i <=nlstate; i++){
1.234     brouard  10198:       j=0;
1.126     brouard  10199:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10200:        if(jj==i) continue;
                   10201:        j++;
                   10202:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10203:        if ((i1 != i) || (j1 != jj)){
                   10204:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10205: It might be a problem of design; if ncovcol and the model are correct\n \
                   10206: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10207:          exit(1);
                   10208:        }
                   10209:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10210:        if(mle==1)
                   10211:          printf("%1d%1d",i,jj);
                   10212:        fprintf(ficlog,"%1d%1d",i,jj);
                   10213:        for(k=1; k<=ncovmodel;k++){
                   10214:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10215:          if(mle==1){
                   10216:            printf(" %lf",param[i][j][k]);
                   10217:            fprintf(ficlog," %lf",param[i][j][k]);
                   10218:          }
                   10219:          else
                   10220:            fprintf(ficlog," %lf",param[i][j][k]);
                   10221:          fprintf(ficparo," %lf",param[i][j][k]);
                   10222:        }
                   10223:        fscanf(ficpar,"\n");
                   10224:        numlinepar++;
                   10225:        if(mle==1)
                   10226:          printf("\n");
                   10227:        fprintf(ficlog,"\n");
                   10228:        fprintf(ficparo,"\n");
1.126     brouard  10229:       }
                   10230:     }  
                   10231:     fflush(ficlog);
1.234     brouard  10232:     
1.251     brouard  10233:     /* Reads parameters values */
1.126     brouard  10234:     p=param[1][1];
1.251     brouard  10235:     pstart=paramstart[1][1];
1.126     brouard  10236:     
                   10237:     /* Reads comments: lines beginning with '#' */
                   10238:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10239:       ungetc(c,ficpar);
                   10240:       fgets(line, MAXLINE, ficpar);
                   10241:       numlinepar++;
1.141     brouard  10242:       fputs(line,stdout);
1.126     brouard  10243:       fputs(line,ficparo);
                   10244:       fputs(line,ficlog);
                   10245:     }
                   10246:     ungetc(c,ficpar);
                   10247: 
                   10248:     for(i=1; i <=nlstate; i++){
                   10249:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  10250:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10251:        if ( (i1-i) * (j1-j) != 0){
                   10252:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   10253:          exit(1);
                   10254:        }
                   10255:        printf("%1d%1d",i,j);
                   10256:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10257:        fprintf(ficlog,"%1d%1d",i1,j1);
                   10258:        for(k=1; k<=ncovmodel;k++){
                   10259:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   10260:          printf(" %le",delti3[i][j][k]);
                   10261:          fprintf(ficparo," %le",delti3[i][j][k]);
                   10262:          fprintf(ficlog," %le",delti3[i][j][k]);
                   10263:        }
                   10264:        fscanf(ficpar,"\n");
                   10265:        numlinepar++;
                   10266:        printf("\n");
                   10267:        fprintf(ficparo,"\n");
                   10268:        fprintf(ficlog,"\n");
1.126     brouard  10269:       }
                   10270:     }
                   10271:     fflush(ficlog);
1.234     brouard  10272:     
1.145     brouard  10273:     /* Reads covariance matrix */
1.126     brouard  10274:     delti=delti3[1][1];
1.220     brouard  10275:                
                   10276:                
1.126     brouard  10277:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  10278:                
1.126     brouard  10279:     /* Reads comments: lines beginning with '#' */
                   10280:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10281:       ungetc(c,ficpar);
                   10282:       fgets(line, MAXLINE, ficpar);
                   10283:       numlinepar++;
1.141     brouard  10284:       fputs(line,stdout);
1.126     brouard  10285:       fputs(line,ficparo);
                   10286:       fputs(line,ficlog);
                   10287:     }
                   10288:     ungetc(c,ficpar);
1.220     brouard  10289:                
1.126     brouard  10290:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10291:     hess=matrix(1,npar,1,npar);
1.131     brouard  10292:     for(i=1; i <=npar; i++)
                   10293:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  10294:                
1.194     brouard  10295:     /* Scans npar lines */
1.126     brouard  10296:     for(i=1; i <=npar; i++){
1.226     brouard  10297:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  10298:       if(count != 3){
1.226     brouard  10299:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10300: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10301: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10302:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  10303: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   10304: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  10305:        exit(1);
1.220     brouard  10306:       }else{
1.226     brouard  10307:        if(mle==1)
                   10308:          printf("%1d%1d%d",i1,j1,jk);
                   10309:       }
                   10310:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   10311:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  10312:       for(j=1; j <=i; j++){
1.226     brouard  10313:        fscanf(ficpar," %le",&matcov[i][j]);
                   10314:        if(mle==1){
                   10315:          printf(" %.5le",matcov[i][j]);
                   10316:        }
                   10317:        fprintf(ficlog," %.5le",matcov[i][j]);
                   10318:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  10319:       }
                   10320:       fscanf(ficpar,"\n");
                   10321:       numlinepar++;
                   10322:       if(mle==1)
1.220     brouard  10323:                                printf("\n");
1.126     brouard  10324:       fprintf(ficlog,"\n");
                   10325:       fprintf(ficparo,"\n");
                   10326:     }
1.194     brouard  10327:     /* End of read covariance matrix npar lines */
1.126     brouard  10328:     for(i=1; i <=npar; i++)
                   10329:       for(j=i+1;j<=npar;j++)
1.226     brouard  10330:        matcov[i][j]=matcov[j][i];
1.126     brouard  10331:     
                   10332:     if(mle==1)
                   10333:       printf("\n");
                   10334:     fprintf(ficlog,"\n");
                   10335:     
                   10336:     fflush(ficlog);
                   10337:     
                   10338:     /*-------- Rewriting parameter file ----------*/
                   10339:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   10340:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   10341:     strcat(rfileres,".");    /* */
                   10342:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10343:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  10344:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10345:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  10346:     }
                   10347:     fprintf(ficres,"#%s\n",version);
                   10348:   }    /* End of mle != -3 */
1.218     brouard  10349:   
1.186     brouard  10350:   /*  Main data
                   10351:    */
1.126     brouard  10352:   n= lastobs;
                   10353:   num=lvector(1,n);
                   10354:   moisnais=vector(1,n);
                   10355:   annais=vector(1,n);
                   10356:   moisdc=vector(1,n);
                   10357:   andc=vector(1,n);
1.220     brouard  10358:   weight=vector(1,n);
1.126     brouard  10359:   agedc=vector(1,n);
                   10360:   cod=ivector(1,n);
1.220     brouard  10361:   for(i=1;i<=n;i++){
1.234     brouard  10362:     num[i]=0;
                   10363:     moisnais[i]=0;
                   10364:     annais[i]=0;
                   10365:     moisdc[i]=0;
                   10366:     andc[i]=0;
                   10367:     agedc[i]=0;
                   10368:     cod[i]=0;
                   10369:     weight[i]=1.0; /* Equal weights, 1 by default */
                   10370:   }
1.126     brouard  10371:   mint=matrix(1,maxwav,1,n);
                   10372:   anint=matrix(1,maxwav,1,n);
1.131     brouard  10373:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  10374:   tab=ivector(1,NCOVMAX);
1.144     brouard  10375:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  10376:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  10377: 
1.136     brouard  10378:   /* Reads data from file datafile */
                   10379:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   10380:     goto end;
                   10381: 
                   10382:   /* Calculation of the number of parameters from char model */
1.234     brouard  10383:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  10384:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   10385:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   10386:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   10387:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  10388:   */
                   10389:   
                   10390:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   10391:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   10392:   TvarsD=ivector(1,NCOVMAX); /*  */
                   10393:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   10394:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  10395:   TvarF=ivector(1,NCOVMAX); /*  */
                   10396:   TvarFind=ivector(1,NCOVMAX); /*  */
                   10397:   TvarV=ivector(1,NCOVMAX); /*  */
                   10398:   TvarVind=ivector(1,NCOVMAX); /*  */
                   10399:   TvarA=ivector(1,NCOVMAX); /*  */
                   10400:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  10401:   TvarFD=ivector(1,NCOVMAX); /*  */
                   10402:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   10403:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   10404:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   10405:   TvarVD=ivector(1,NCOVMAX); /*  */
                   10406:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   10407:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   10408:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   10409: 
1.230     brouard  10410:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  10411:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  10412:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   10413:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   10414:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  10415:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   10416:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   10417:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   10418:   */
                   10419:   /* For model-covariate k tells which data-covariate to use but
                   10420:     because this model-covariate is a construction we invent a new column
                   10421:     ncovcol + k1
                   10422:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   10423:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  10424:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   10425:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  10426:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   10427:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  10428:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  10429:   */
1.145     brouard  10430:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   10431:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  10432:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   10433:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  10434:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  10435:                         4 covariates (3 plus signs)
                   10436:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   10437:                      */  
1.230     brouard  10438:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  10439:                                * individual dummy, fixed or varying:
                   10440:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   10441:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  10442:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   10443:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   10444:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   10445:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   10446:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  10447:                                * individual quantitative, fixed or varying:
                   10448:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   10449:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   10450:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  10451: /* Main decodemodel */
                   10452: 
1.187     brouard  10453: 
1.223     brouard  10454:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  10455:     goto end;
                   10456: 
1.137     brouard  10457:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   10458:     nbwarn++;
                   10459:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10460:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   10461:   }
1.136     brouard  10462:     /*  if(mle==1){*/
1.137     brouard  10463:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   10464:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  10465:   }
                   10466: 
                   10467:     /*-calculation of age at interview from date of interview and age at death -*/
                   10468:   agev=matrix(1,maxwav,1,imx);
                   10469: 
                   10470:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   10471:     goto end;
                   10472: 
1.126     brouard  10473: 
1.136     brouard  10474:   agegomp=(int)agemin;
                   10475:   free_vector(moisnais,1,n);
                   10476:   free_vector(annais,1,n);
1.126     brouard  10477:   /* free_matrix(mint,1,maxwav,1,n);
                   10478:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  10479:   /* free_vector(moisdc,1,n); */
                   10480:   /* free_vector(andc,1,n); */
1.145     brouard  10481:   /* */
                   10482:   
1.126     brouard  10483:   wav=ivector(1,imx);
1.214     brouard  10484:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10485:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10486:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   10487:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   10488:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   10489:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  10490:    
                   10491:   /* Concatenates waves */
1.214     brouard  10492:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   10493:      Death is a valid wave (if date is known).
                   10494:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   10495:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   10496:      and mw[mi+1][i]. dh depends on stepm.
                   10497:   */
                   10498: 
1.126     brouard  10499:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  10500:   /* Concatenates waves */
1.145     brouard  10501:  
1.215     brouard  10502:   free_vector(moisdc,1,n);
                   10503:   free_vector(andc,1,n);
                   10504: 
1.126     brouard  10505:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   10506:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   10507:   ncodemax[1]=1;
1.145     brouard  10508:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  10509:   cptcoveff=0;
1.220     brouard  10510:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   10511:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  10512:   }
                   10513:   
                   10514:   ncovcombmax=pow(2,cptcoveff);
                   10515:   invalidvarcomb=ivector(1, ncovcombmax); 
                   10516:   for(i=1;i<ncovcombmax;i++)
                   10517:     invalidvarcomb[i]=0;
                   10518:   
1.211     brouard  10519:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  10520:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  10521:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  10522:   
1.200     brouard  10523:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  10524:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  10525:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  10526:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   10527:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   10528:    * (currently 0 or 1) in the data.
                   10529:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   10530:    * corresponding modality (h,j).
                   10531:    */
                   10532: 
1.145     brouard  10533:   h=0;
                   10534:   /*if (cptcovn > 0) */
1.126     brouard  10535:   m=pow(2,cptcoveff);
                   10536:  
1.144     brouard  10537:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  10538:           * For k=4 covariates, h goes from 1 to m=2**k
                   10539:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   10540:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  10541:           *     h\k   1     2     3     4
1.143     brouard  10542:           *______________________________  
                   10543:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   10544:           *     2     2     1     1     1
                   10545:           *     3 i=2 1     2     1     1
                   10546:           *     4     2     2     1     1
                   10547:           *     5 i=3 1 i=2 1     2     1
                   10548:           *     6     2     1     2     1
                   10549:           *     7 i=4 1     2     2     1
                   10550:           *     8     2     2     2     1
1.197     brouard  10551:           *     9 i=5 1 i=3 1 i=2 1     2
                   10552:           *    10     2     1     1     2
                   10553:           *    11 i=6 1     2     1     2
                   10554:           *    12     2     2     1     2
                   10555:           *    13 i=7 1 i=4 1     2     2    
                   10556:           *    14     2     1     2     2
                   10557:           *    15 i=8 1     2     2     2
                   10558:           *    16     2     2     2     2
1.143     brouard  10559:           */
1.212     brouard  10560:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  10561:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   10562:      * and the value of each covariate?
                   10563:      * V1=1, V2=1, V3=2, V4=1 ?
                   10564:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   10565:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   10566:      * In order to get the real value in the data, we use nbcode
                   10567:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   10568:      * We are keeping this crazy system in order to be able (in the future?) 
                   10569:      * to have more than 2 values (0 or 1) for a covariate.
                   10570:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   10571:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   10572:      *              bbbbbbbb
                   10573:      *              76543210     
                   10574:      *   h-1        00000101 (6-1=5)
1.219     brouard  10575:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  10576:      *           &
                   10577:      *     1        00000001 (1)
1.219     brouard  10578:      *              00000000        = 1 & ((h-1) >> (k-1))
                   10579:      *          +1= 00000001 =1 
1.211     brouard  10580:      *
                   10581:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   10582:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   10583:      *    >>k'            11
                   10584:      *          &   00000001
                   10585:      *            = 00000001
                   10586:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   10587:      * Reverse h=6 and m=16?
                   10588:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   10589:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   10590:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   10591:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   10592:      * V3=decodtabm(14,3,2**4)=2
                   10593:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   10594:      *(h-1) >> (j-1)    0011 =13 >> 2
                   10595:      *          &1 000000001
                   10596:      *           = 000000001
                   10597:      *         +1= 000000010 =2
                   10598:      *                  2211
                   10599:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   10600:      *                  V3=2
1.220     brouard  10601:                 * codtabm and decodtabm are identical
1.211     brouard  10602:      */
                   10603: 
1.145     brouard  10604: 
                   10605:  free_ivector(Ndum,-1,NCOVMAX);
                   10606: 
                   10607: 
1.126     brouard  10608:     
1.186     brouard  10609:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  10610:   strcpy(optionfilegnuplot,optionfilefiname);
                   10611:   if(mle==-3)
1.201     brouard  10612:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  10613:   strcat(optionfilegnuplot,".gp");
                   10614: 
                   10615:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   10616:     printf("Problem with file %s",optionfilegnuplot);
                   10617:   }
                   10618:   else{
1.204     brouard  10619:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  10620:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  10621:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   10622:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  10623:   }
                   10624:   /*  fclose(ficgp);*/
1.186     brouard  10625: 
                   10626: 
                   10627:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  10628: 
                   10629:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   10630:   if(mle==-3)
1.201     brouard  10631:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  10632:   strcat(optionfilehtm,".htm");
                   10633:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  10634:     printf("Problem with %s \n",optionfilehtm);
                   10635:     exit(0);
1.126     brouard  10636:   }
                   10637: 
                   10638:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   10639:   strcat(optionfilehtmcov,"-cov.htm");
                   10640:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   10641:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   10642:   }
                   10643:   else{
                   10644:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   10645: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10646: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  10647:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   10648:   }
                   10649: 
1.213     brouard  10650:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  10651: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   10652: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  10653: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  10654: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  10655: \n\
                   10656: <hr  size=\"2\" color=\"#EC5E5E\">\
                   10657:  <ul><li><h4>Parameter files</h4>\n\
                   10658:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   10659:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   10660:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   10661:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   10662:  - Date and time at start: %s</ul>\n",\
                   10663:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   10664:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   10665:          fileres,fileres,\
                   10666:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   10667:   fflush(fichtm);
                   10668: 
                   10669:   strcpy(pathr,path);
                   10670:   strcat(pathr,optionfilefiname);
1.184     brouard  10671: #ifdef WIN32
                   10672:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   10673: #else
1.126     brouard  10674:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  10675: #endif
                   10676:          
1.126     brouard  10677:   
1.220     brouard  10678:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   10679:                 and for any valid combination of covariates
1.126     brouard  10680:      and prints on file fileres'p'. */
1.251     brouard  10681:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  10682:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  10683: 
                   10684:   fprintf(fichtm,"\n");
                   10685:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   10686: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   10687: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   10688:          imx,agemin,agemax,jmin,jmax,jmean);
                   10689:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.220     brouard  10690:        oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10691:        newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10692:        savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   10693:        oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  10694: 
1.126     brouard  10695:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   10696:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   10697:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   10698: 
                   10699:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  10700:   /* For mortality only */
1.126     brouard  10701:   if (mle==-3){
1.136     brouard  10702:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  10703:     for(i=1;i<=NDIM;i++)
                   10704:       for(j=1;j<=NDIM;j++)
                   10705:        ximort[i][j]=0.;
1.186     brouard  10706:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  10707:     cens=ivector(1,n);
                   10708:     ageexmed=vector(1,n);
                   10709:     agecens=vector(1,n);
                   10710:     dcwave=ivector(1,n);
1.223     brouard  10711:                
1.126     brouard  10712:     for (i=1; i<=imx; i++){
                   10713:       dcwave[i]=-1;
                   10714:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  10715:        if (s[m][i]>nlstate) {
                   10716:          dcwave[i]=m;
                   10717:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   10718:          break;
                   10719:        }
1.126     brouard  10720:     }
1.226     brouard  10721:     
1.126     brouard  10722:     for (i=1; i<=imx; i++) {
                   10723:       if (wav[i]>0){
1.226     brouard  10724:        ageexmed[i]=agev[mw[1][i]][i];
                   10725:        j=wav[i];
                   10726:        agecens[i]=1.; 
                   10727:        
                   10728:        if (ageexmed[i]> 1 && wav[i] > 0){
                   10729:          agecens[i]=agev[mw[j][i]][i];
                   10730:          cens[i]= 1;
                   10731:        }else if (ageexmed[i]< 1) 
                   10732:          cens[i]= -1;
                   10733:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   10734:          cens[i]=0 ;
1.126     brouard  10735:       }
                   10736:       else cens[i]=-1;
                   10737:     }
                   10738:     
                   10739:     for (i=1;i<=NDIM;i++) {
                   10740:       for (j=1;j<=NDIM;j++)
1.226     brouard  10741:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  10742:     }
                   10743:     
1.145     brouard  10744:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  10745:     /*printf("%lf %lf", p[1], p[2]);*/
                   10746:     
                   10747:     
1.136     brouard  10748: #ifdef GSL
                   10749:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  10750: #else
1.126     brouard  10751:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  10752: #endif
1.201     brouard  10753:     strcpy(filerespow,"POW-MORT_"); 
                   10754:     strcat(filerespow,fileresu);
1.126     brouard  10755:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   10756:       printf("Problem with resultfile: %s\n", filerespow);
                   10757:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   10758:     }
1.136     brouard  10759: #ifdef GSL
                   10760:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  10761: #else
1.126     brouard  10762:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  10763: #endif
1.126     brouard  10764:     /*  for (i=1;i<=nlstate;i++)
                   10765:        for(j=1;j<=nlstate+ndeath;j++)
                   10766:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   10767:     */
                   10768:     fprintf(ficrespow,"\n");
1.136     brouard  10769: #ifdef GSL
                   10770:     /* gsl starts here */ 
                   10771:     T = gsl_multimin_fminimizer_nmsimplex;
                   10772:     gsl_multimin_fminimizer *sfm = NULL;
                   10773:     gsl_vector *ss, *x;
                   10774:     gsl_multimin_function minex_func;
                   10775: 
                   10776:     /* Initial vertex size vector */
                   10777:     ss = gsl_vector_alloc (NDIM);
                   10778:     
                   10779:     if (ss == NULL){
                   10780:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   10781:     }
                   10782:     /* Set all step sizes to 1 */
                   10783:     gsl_vector_set_all (ss, 0.001);
                   10784: 
                   10785:     /* Starting point */
1.126     brouard  10786:     
1.136     brouard  10787:     x = gsl_vector_alloc (NDIM);
                   10788:     
                   10789:     if (x == NULL){
                   10790:       gsl_vector_free(ss);
                   10791:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   10792:     }
                   10793:   
                   10794:     /* Initialize method and iterate */
                   10795:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  10796:     /*     gsl_vector_set(x, 0, 0.0268); */
                   10797:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  10798:     gsl_vector_set(x, 0, p[1]);
                   10799:     gsl_vector_set(x, 1, p[2]);
                   10800: 
                   10801:     minex_func.f = &gompertz_f;
                   10802:     minex_func.n = NDIM;
                   10803:     minex_func.params = (void *)&p; /* ??? */
                   10804:     
                   10805:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   10806:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   10807:     
                   10808:     printf("Iterations beginning .....\n\n");
                   10809:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   10810: 
                   10811:     iteri=0;
                   10812:     while (rval == GSL_CONTINUE){
                   10813:       iteri++;
                   10814:       status = gsl_multimin_fminimizer_iterate(sfm);
                   10815:       
                   10816:       if (status) printf("error: %s\n", gsl_strerror (status));
                   10817:       fflush(0);
                   10818:       
                   10819:       if (status) 
                   10820:         break;
                   10821:       
                   10822:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   10823:       ssval = gsl_multimin_fminimizer_size (sfm);
                   10824:       
                   10825:       if (rval == GSL_SUCCESS)
                   10826:         printf ("converged to a local maximum at\n");
                   10827:       
                   10828:       printf("%5d ", iteri);
                   10829:       for (it = 0; it < NDIM; it++){
                   10830:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   10831:       }
                   10832:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   10833:     }
                   10834:     
                   10835:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   10836:     
                   10837:     gsl_vector_free(x); /* initial values */
                   10838:     gsl_vector_free(ss); /* inital step size */
                   10839:     for (it=0; it<NDIM; it++){
                   10840:       p[it+1]=gsl_vector_get(sfm->x,it);
                   10841:       fprintf(ficrespow," %.12lf", p[it]);
                   10842:     }
                   10843:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   10844: #endif
                   10845: #ifdef POWELL
                   10846:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   10847: #endif  
1.126     brouard  10848:     fclose(ficrespow);
                   10849:     
1.203     brouard  10850:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  10851: 
                   10852:     for(i=1; i <=NDIM; i++)
                   10853:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  10854:                                matcov[i][j]=matcov[j][i];
1.126     brouard  10855:     
                   10856:     printf("\nCovariance matrix\n ");
1.203     brouard  10857:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  10858:     for(i=1; i <=NDIM; i++) {
                   10859:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  10860:                                printf("%f ",matcov[i][j]);
                   10861:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  10862:       }
1.203     brouard  10863:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  10864:     }
                   10865:     
                   10866:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  10867:     for (i=1;i<=NDIM;i++) {
1.126     brouard  10868:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  10869:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   10870:     }
1.126     brouard  10871:     lsurv=vector(1,AGESUP);
                   10872:     lpop=vector(1,AGESUP);
                   10873:     tpop=vector(1,AGESUP);
                   10874:     lsurv[agegomp]=100000;
                   10875:     
                   10876:     for (k=agegomp;k<=AGESUP;k++) {
                   10877:       agemortsup=k;
                   10878:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   10879:     }
                   10880:     
                   10881:     for (k=agegomp;k<agemortsup;k++)
                   10882:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   10883:     
                   10884:     for (k=agegomp;k<agemortsup;k++){
                   10885:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   10886:       sumlpop=sumlpop+lpop[k];
                   10887:     }
                   10888:     
                   10889:     tpop[agegomp]=sumlpop;
                   10890:     for (k=agegomp;k<(agemortsup-3);k++){
                   10891:       /*  tpop[k+1]=2;*/
                   10892:       tpop[k+1]=tpop[k]-lpop[k];
                   10893:     }
                   10894:     
                   10895:     
                   10896:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   10897:     for (k=agegomp;k<(agemortsup-2);k++) 
                   10898:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   10899:     
                   10900:     
                   10901:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  10902:                ageminpar=50;
                   10903:                agemaxpar=100;
1.194     brouard  10904:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   10905:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10906: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10907: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   10908:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   10909: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   10910: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  10911:     }else{
                   10912:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   10913:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  10914:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  10915:                }
1.201     brouard  10916:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  10917:                     stepm, weightopt,\
                   10918:                     model,imx,p,matcov,agemortsup);
                   10919:     
                   10920:     free_vector(lsurv,1,AGESUP);
                   10921:     free_vector(lpop,1,AGESUP);
                   10922:     free_vector(tpop,1,AGESUP);
1.220     brouard  10923:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  10924:     free_ivector(cens,1,n);
                   10925:     free_vector(agecens,1,n);
                   10926:     free_ivector(dcwave,1,n);
1.220     brouard  10927: #ifdef GSL
1.136     brouard  10928: #endif
1.186     brouard  10929:   } /* Endof if mle==-3 mortality only */
1.205     brouard  10930:   /* Standard  */
                   10931:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   10932:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10933:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  10934:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  10935:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10936:     for (k=1; k<=npar;k++)
                   10937:       printf(" %d %8.5f",k,p[k]);
                   10938:     printf("\n");
1.205     brouard  10939:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   10940:       /* mlikeli uses func not funcone */
1.247     brouard  10941:       /* for(i=1;i<nlstate;i++){ */
                   10942:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10943:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10944:       /* } */
1.205     brouard  10945:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   10946:     }
                   10947:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   10948:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   10949:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   10950:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10951:     }
                   10952:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  10953:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   10954:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   10955:     for (k=1; k<=npar;k++)
                   10956:       printf(" %d %8.5f",k,p[k]);
                   10957:     printf("\n");
                   10958:     
                   10959:     /*--------- results files --------------*/
1.224     brouard  10960:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  10961:     
                   10962:     
                   10963:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10964:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10965:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   10966:     for(i=1,jk=1; i <=nlstate; i++){
                   10967:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  10968:        if (k != i) {
                   10969:          printf("%d%d ",i,k);
                   10970:          fprintf(ficlog,"%d%d ",i,k);
                   10971:          fprintf(ficres,"%1d%1d ",i,k);
                   10972:          for(j=1; j <=ncovmodel; j++){
                   10973:            printf("%12.7f ",p[jk]);
                   10974:            fprintf(ficlog,"%12.7f ",p[jk]);
                   10975:            fprintf(ficres,"%12.7f ",p[jk]);
                   10976:            jk++; 
                   10977:          }
                   10978:          printf("\n");
                   10979:          fprintf(ficlog,"\n");
                   10980:          fprintf(ficres,"\n");
                   10981:        }
1.126     brouard  10982:       }
                   10983:     }
1.203     brouard  10984:     if(mle != 0){
                   10985:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  10986:       ftolhess=ftol; /* Usually correct */
1.203     brouard  10987:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   10988:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10989:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   10990:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  10991:        for(k=1; k <=(nlstate+ndeath); k++){
                   10992:          if (k != i) {
                   10993:            printf("%d%d ",i,k);
                   10994:            fprintf(ficlog,"%d%d ",i,k);
                   10995:            for(j=1; j <=ncovmodel; j++){
                   10996:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10997:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   10998:              jk++; 
                   10999:            }
                   11000:            printf("\n");
                   11001:            fprintf(ficlog,"\n");
                   11002:          }
                   11003:        }
1.193     brouard  11004:       }
1.203     brouard  11005:     } /* end of hesscov and Wald tests */
1.225     brouard  11006:     
1.203     brouard  11007:     /*  */
1.126     brouard  11008:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11009:     printf("# Scales (for hessian or gradient estimation)\n");
                   11010:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11011:     for(i=1,jk=1; i <=nlstate; i++){
                   11012:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11013:        if (j!=i) {
                   11014:          fprintf(ficres,"%1d%1d",i,j);
                   11015:          printf("%1d%1d",i,j);
                   11016:          fprintf(ficlog,"%1d%1d",i,j);
                   11017:          for(k=1; k<=ncovmodel;k++){
                   11018:            printf(" %.5e",delti[jk]);
                   11019:            fprintf(ficlog," %.5e",delti[jk]);
                   11020:            fprintf(ficres," %.5e",delti[jk]);
                   11021:            jk++;
                   11022:          }
                   11023:          printf("\n");
                   11024:          fprintf(ficlog,"\n");
                   11025:          fprintf(ficres,"\n");
                   11026:        }
1.126     brouard  11027:       }
                   11028:     }
                   11029:     
                   11030:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11031:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11032:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11033:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11034:     /* # 121 Var(a12)\n\ */
                   11035:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11036:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11037:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11038:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11039:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11040:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11041:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11042:     
                   11043:     
                   11044:     /* Just to have a covariance matrix which will be more understandable
                   11045:        even is we still don't want to manage dictionary of variables
                   11046:     */
                   11047:     for(itimes=1;itimes<=2;itimes++){
                   11048:       jj=0;
                   11049:       for(i=1; i <=nlstate; i++){
1.225     brouard  11050:        for(j=1; j <=nlstate+ndeath; j++){
                   11051:          if(j==i) continue;
                   11052:          for(k=1; k<=ncovmodel;k++){
                   11053:            jj++;
                   11054:            ca[0]= k+'a'-1;ca[1]='\0';
                   11055:            if(itimes==1){
                   11056:              if(mle>=1)
                   11057:                printf("#%1d%1d%d",i,j,k);
                   11058:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11059:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11060:            }else{
                   11061:              if(mle>=1)
                   11062:                printf("%1d%1d%d",i,j,k);
                   11063:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11064:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11065:            }
                   11066:            ll=0;
                   11067:            for(li=1;li <=nlstate; li++){
                   11068:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11069:                if(lj==li) continue;
                   11070:                for(lk=1;lk<=ncovmodel;lk++){
                   11071:                  ll++;
                   11072:                  if(ll<=jj){
                   11073:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11074:                    if(ll<jj){
                   11075:                      if(itimes==1){
                   11076:                        if(mle>=1)
                   11077:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11078:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11079:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11080:                      }else{
                   11081:                        if(mle>=1)
                   11082:                          printf(" %.5e",matcov[jj][ll]); 
                   11083:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11084:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11085:                      }
                   11086:                    }else{
                   11087:                      if(itimes==1){
                   11088:                        if(mle>=1)
                   11089:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11090:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11091:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11092:                      }else{
                   11093:                        if(mle>=1)
                   11094:                          printf(" %.7e",matcov[jj][ll]); 
                   11095:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11096:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11097:                      }
                   11098:                    }
                   11099:                  }
                   11100:                } /* end lk */
                   11101:              } /* end lj */
                   11102:            } /* end li */
                   11103:            if(mle>=1)
                   11104:              printf("\n");
                   11105:            fprintf(ficlog,"\n");
                   11106:            fprintf(ficres,"\n");
                   11107:            numlinepar++;
                   11108:          } /* end k*/
                   11109:        } /*end j */
1.126     brouard  11110:       } /* end i */
                   11111:     } /* end itimes */
                   11112:     
                   11113:     fflush(ficlog);
                   11114:     fflush(ficres);
1.225     brouard  11115:     while(fgets(line, MAXLINE, ficpar)) {
                   11116:       /* If line starts with a # it is a comment */
                   11117:       if (line[0] == '#') {
                   11118:        numlinepar++;
                   11119:        fputs(line,stdout);
                   11120:        fputs(line,ficparo);
                   11121:        fputs(line,ficlog);
                   11122:        continue;
                   11123:       }else
                   11124:        break;
                   11125:     }
                   11126:     
1.209     brouard  11127:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11128:     /*   ungetc(c,ficpar); */
                   11129:     /*   fgets(line, MAXLINE, ficpar); */
                   11130:     /*   fputs(line,stdout); */
                   11131:     /*   fputs(line,ficparo); */
                   11132:     /* } */
                   11133:     /* ungetc(c,ficpar); */
1.126     brouard  11134:     
                   11135:     estepm=0;
1.209     brouard  11136:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11137:       
                   11138:       if (num_filled != 6) {
                   11139:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11140:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11141:        goto end;
                   11142:       }
                   11143:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11144:     }
                   11145:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11146:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11147:     
1.209     brouard  11148:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11149:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11150:     if (fage <= 2) {
                   11151:       bage = ageminpar;
                   11152:       fage = agemaxpar;
                   11153:     }
                   11154:     
                   11155:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11156:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11157:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11158:                
1.186     brouard  11159:     /* Other stuffs, more or less useful */    
1.254     brouard  11160:     while(fgets(line, MAXLINE, ficpar)) {
                   11161:       /* If line starts with a # it is a comment */
                   11162:       if (line[0] == '#') {
                   11163:        numlinepar++;
                   11164:        fputs(line,stdout);
                   11165:        fputs(line,ficparo);
                   11166:        fputs(line,ficlog);
                   11167:        continue;
                   11168:       }else
                   11169:        break;
                   11170:     }
                   11171: 
                   11172:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11173:       
                   11174:       if (num_filled != 7) {
                   11175:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11176:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11177:        goto end;
                   11178:       }
                   11179:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11180:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11181:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11182:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11183:     }
1.254     brouard  11184: 
                   11185:     while(fgets(line, MAXLINE, ficpar)) {
                   11186:       /* If line starts with a # it is a comment */
                   11187:       if (line[0] == '#') {
                   11188:        numlinepar++;
                   11189:        fputs(line,stdout);
                   11190:        fputs(line,ficparo);
                   11191:        fputs(line,ficlog);
                   11192:        continue;
                   11193:       }else
                   11194:        break;
1.126     brouard  11195:     }
                   11196:     
                   11197:     
                   11198:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11199:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11200:     
1.254     brouard  11201:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11202:       if (num_filled != 1) {
                   11203:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11204:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11205:        goto end;
                   11206:       }
                   11207:       printf("pop_based=%d\n",popbased);
                   11208:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11209:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11210:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11211:     }
                   11212:      
1.258     brouard  11213:     /* Results */
                   11214:     nresult=0;
                   11215:     do{
                   11216:       if(!fgets(line, MAXLINE, ficpar)){
                   11217:        endishere=1;
                   11218:        parameterline=14;
                   11219:       }else if (line[0] == '#') {
                   11220:        /* If line starts with a # it is a comment */
1.254     brouard  11221:        numlinepar++;
                   11222:        fputs(line,stdout);
                   11223:        fputs(line,ficparo);
                   11224:        fputs(line,ficlog);
                   11225:        continue;
1.258     brouard  11226:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   11227:        parameterline=11;
                   11228:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   11229:        parameterline=12;
                   11230:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   11231:        parameterline=13;
                   11232:       else{
                   11233:        parameterline=14;
1.254     brouard  11234:       }
1.258     brouard  11235:       switch (parameterline){ 
                   11236:       case 11:
                   11237:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11238:          if (num_filled != 8) {
                   11239:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11240:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11241:            goto end;
                   11242:          }
                   11243:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11244:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11245:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11246:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   11247:          /* day and month of proj2 are not used but only year anproj2.*/
                   11248:        }
1.254     brouard  11249:        break;
1.258     brouard  11250:       case 12:
                   11251:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   11252:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   11253:          if (num_filled != 8) {
1.262     brouard  11254:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11255:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  11256:            goto end;
                   11257:          }
                   11258:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11259:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11260:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11261:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   11262:          /* day and month of proj2 are not used but only year anproj2.*/
                   11263:        }
1.230     brouard  11264:        break;
1.258     brouard  11265:       case 13:
                   11266:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   11267:          if (num_filled == 0){
                   11268:            resultline[0]='\0';
                   11269:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11270:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   11271:            break;
                   11272:          } else if (num_filled != 1){
                   11273:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11274:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   11275:          }
                   11276:          nresult++; /* Sum of resultlines */
                   11277:          printf("Result %d: result=%s\n",nresult, resultline);
                   11278:          if(nresult > MAXRESULTLINES){
                   11279:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11280:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   11281:            goto end;
                   11282:          }
                   11283:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   11284:          fprintf(ficparo,"result: %s\n",resultline);
                   11285:          fprintf(ficres,"result: %s\n",resultline);
                   11286:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  11287:          break;
1.258     brouard  11288:        case 14: 
1.259     brouard  11289:          if(ncovmodel >2 && nresult==0 ){
                   11290:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  11291:            goto end;
                   11292:          }
1.259     brouard  11293:          break;
1.258     brouard  11294:        default:
                   11295:          nresult=1;
                   11296:          decoderesult(".",nresult ); /* No covariate */
                   11297:        }
                   11298:       } /* End switch parameterline */
                   11299:     }while(endishere==0); /* End do */
1.126     brouard  11300:     
1.230     brouard  11301:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  11302:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  11303:     
                   11304:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  11305:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  11306:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11307: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11308: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  11309:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  11310: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11311: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11312:     }else{
1.218     brouard  11313:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p);
1.220     brouard  11314:     }
                   11315:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  11316:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  11317:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  11318:                
1.225     brouard  11319:     /*------------ free_vector  -------------*/
                   11320:     /*  chdir(path); */
1.220     brouard  11321:                
1.215     brouard  11322:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   11323:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   11324:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   11325:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  11326:     free_lvector(num,1,n);
                   11327:     free_vector(agedc,1,n);
                   11328:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   11329:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   11330:     fclose(ficparo);
                   11331:     fclose(ficres);
1.220     brouard  11332:                
                   11333:                
1.186     brouard  11334:     /* Other results (useful)*/
1.220     brouard  11335:                
                   11336:                
1.126     brouard  11337:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  11338:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   11339:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  11340:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  11341:     fclose(ficrespl);
                   11342: 
                   11343:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  11344:     /*#include "hpijx.h"*/
                   11345:     hPijx(p, bage, fage);
1.145     brouard  11346:     fclose(ficrespij);
1.227     brouard  11347:     
1.220     brouard  11348:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  11349:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  11350:     k=1;
1.126     brouard  11351:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  11352:     
1.219     brouard  11353:     /* Prevalence for each covariates in probs[age][status][cov] */
1.218     brouard  11354:     probs= ma3x(1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.126     brouard  11355:     for(i=1;i<=AGESUP;i++)
1.219     brouard  11356:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  11357:        for(k=1;k<=ncovcombmax;k++)
                   11358:          probs[i][j][k]=0.;
1.219     brouard  11359:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
                   11360:     if (mobilav!=0 ||mobilavproj !=0 ) {
                   11361:       mobaverages= ma3x(1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.227     brouard  11362:       for(i=1;i<=AGESUP;i++)
                   11363:        for(j=1;j<=nlstate;j++)
                   11364:          for(k=1;k<=ncovcombmax;k++)
                   11365:            mobaverages[i][j][k]=0.;
1.219     brouard  11366:       mobaverage=mobaverages;
                   11367:       if (mobilav!=0) {
1.235     brouard  11368:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  11369:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  11370:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   11371:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   11372:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   11373:        }
1.219     brouard  11374:       }
                   11375:       /* /\* Prevalence for each covariates in probs[age][status][cov] *\/ */
                   11376:       /* prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   11377:       else if (mobilavproj !=0) {
1.235     brouard  11378:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  11379:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  11380:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   11381:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11382:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   11383:        }
1.219     brouard  11384:       }
                   11385:     }/* end if moving average */
1.227     brouard  11386:     
1.126     brouard  11387:     /*---------- Forecasting ------------------*/
                   11388:     /*if((stepm == 1) && (strcmp(model,".")==0)){*/
                   11389:     if(prevfcast==1){
                   11390:       /*    if(stepm ==1){*/
1.225     brouard  11391:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  11392:     }
1.217     brouard  11393:     if(backcast==1){
1.219     brouard  11394:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11395:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   11396:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   11397: 
                   11398:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   11399: 
                   11400:       bprlim=matrix(1,nlstate,1,nlstate);
                   11401:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   11402:       fclose(ficresplb);
                   11403: 
1.222     brouard  11404:       hBijx(p, bage, fage, mobaverage);
                   11405:       fclose(ficrespijb);
1.219     brouard  11406:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11407: 
                   11408:       /* prevbackforecast(fileresu, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, mobilavproj,
1.225     brouard  11409:         bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
1.219     brouard  11410:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11411:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11412:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   11413:     }
1.217     brouard  11414:     
1.186     brouard  11415:  
                   11416:     /* ------ Other prevalence ratios------------ */
1.126     brouard  11417: 
1.215     brouard  11418:     free_ivector(wav,1,imx);
                   11419:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   11420:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   11421:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  11422:                
                   11423:                
1.127     brouard  11424:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  11425:                
1.201     brouard  11426:     strcpy(filerese,"E_");
                   11427:     strcat(filerese,fileresu);
1.126     brouard  11428:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   11429:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11430:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   11431:     }
1.208     brouard  11432:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   11433:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  11434: 
                   11435:     pstamp(ficreseij);
1.219     brouard  11436:                
1.235     brouard  11437:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11438:     if (cptcovn < 1){i1=1;}
                   11439:     
                   11440:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11441:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11442:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11443:        continue;
1.219     brouard  11444:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  11445:       printf("\n#****** ");
1.225     brouard  11446:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11447:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11448:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11449:       }
                   11450:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11451:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11452:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  11453:       }
                   11454:       fprintf(ficreseij,"******\n");
1.235     brouard  11455:       printf("******\n");
1.219     brouard  11456:       
                   11457:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11458:       oldm=oldms;savm=savms;
1.235     brouard  11459:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  11460:       
1.219     brouard  11461:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  11462:     }
                   11463:     fclose(ficreseij);
1.208     brouard  11464:     printf("done evsij\n");fflush(stdout);
                   11465:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.218     brouard  11466:                
1.227     brouard  11467:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  11468:                
                   11469:                
1.201     brouard  11470:     strcpy(filerest,"T_");
                   11471:     strcat(filerest,fileresu);
1.127     brouard  11472:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   11473:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   11474:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   11475:     }
1.208     brouard  11476:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   11477:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.218     brouard  11478:                
1.126     brouard  11479: 
1.201     brouard  11480:     strcpy(fileresstde,"STDE_");
                   11481:     strcat(fileresstde,fileresu);
1.126     brouard  11482:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  11483:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   11484:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  11485:     }
1.227     brouard  11486:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   11487:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  11488: 
1.201     brouard  11489:     strcpy(filerescve,"CVE_");
                   11490:     strcat(filerescve,fileresu);
1.126     brouard  11491:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  11492:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   11493:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  11494:     }
1.227     brouard  11495:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   11496:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  11497: 
1.201     brouard  11498:     strcpy(fileresv,"V_");
                   11499:     strcat(fileresv,fileresu);
1.126     brouard  11500:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   11501:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11502:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   11503:     }
1.227     brouard  11504:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   11505:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  11506: 
1.145     brouard  11507:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11508:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   11509:           
1.235     brouard  11510:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   11511:     if (cptcovn < 1){i1=1;}
                   11512:     
                   11513:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11514:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  11515:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11516:        continue;
1.242     brouard  11517:       printf("\n#****** Result for:");
                   11518:       fprintf(ficrest,"\n#****** Result for:");
                   11519:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  11520:       for(j=1;j<=cptcoveff;j++){ 
                   11521:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11522:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11523:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11524:       }
1.235     brouard  11525:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11526:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11527:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11528:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11529:       }        
1.208     brouard  11530:       fprintf(ficrest,"******\n");
1.227     brouard  11531:       fprintf(ficlog,"******\n");
                   11532:       printf("******\n");
1.208     brouard  11533:       
                   11534:       fprintf(ficresstdeij,"\n#****** ");
                   11535:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  11536:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  11537:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11538:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  11539:       }
1.235     brouard  11540:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11541:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11542:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11543:       }        
1.208     brouard  11544:       fprintf(ficresstdeij,"******\n");
                   11545:       fprintf(ficrescveij,"******\n");
                   11546:       
                   11547:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  11548:       /* pstamp(ficresvij); */
1.225     brouard  11549:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  11550:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  11551:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11552:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11553:       }        
1.208     brouard  11554:       fprintf(ficresvij,"******\n");
                   11555:       
                   11556:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11557:       oldm=oldms;savm=savms;
1.235     brouard  11558:       printf(" cvevsij ");
                   11559:       fprintf(ficlog, " cvevsij ");
                   11560:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  11561:       printf(" end cvevsij \n ");
                   11562:       fprintf(ficlog, " end cvevsij \n ");
                   11563:       
                   11564:       /*
                   11565:        */
                   11566:       /* goto endfree; */
                   11567:       
                   11568:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   11569:       pstamp(ficrest);
                   11570:       
                   11571:       
                   11572:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  11573:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   11574:        cptcod= 0; /* To be deleted */
                   11575:        printf("varevsij vpopbased=%d \n",vpopbased);
                   11576:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  11577:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  11578:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   11579:        if(vpopbased==1)
                   11580:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   11581:        else
                   11582:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   11583:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   11584:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   11585:        fprintf(ficrest,"\n");
                   11586:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   11587:        epj=vector(1,nlstate+1);
                   11588:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   11589:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   11590:        for(age=bage; age <=fage ;age++){
1.235     brouard  11591:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  11592:          if (vpopbased==1) {
                   11593:            if(mobilav ==0){
                   11594:              for(i=1; i<=nlstate;i++)
                   11595:                prlim[i][i]=probs[(int)age][i][k];
                   11596:            }else{ /* mobilav */ 
                   11597:              for(i=1; i<=nlstate;i++)
                   11598:                prlim[i][i]=mobaverage[(int)age][i][k];
                   11599:            }
                   11600:          }
1.219     brouard  11601:          
1.227     brouard  11602:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   11603:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   11604:          /* printf(" age %4.0f ",age); */
                   11605:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   11606:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   11607:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   11608:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   11609:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   11610:            }
                   11611:            epj[nlstate+1] +=epj[j];
                   11612:          }
                   11613:          /* printf(" age %4.0f \n",age); */
1.219     brouard  11614:          
1.227     brouard  11615:          for(i=1, vepp=0.;i <=nlstate;i++)
                   11616:            for(j=1;j <=nlstate;j++)
                   11617:              vepp += vareij[i][j][(int)age];
                   11618:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   11619:          for(j=1;j <=nlstate;j++){
                   11620:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   11621:          }
                   11622:          fprintf(ficrest,"\n");
                   11623:        }
1.208     brouard  11624:       } /* End vpopbased */
                   11625:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11626:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   11627:       free_vector(epj,1,nlstate+1);
1.235     brouard  11628:       printf("done selection\n");fflush(stdout);
                   11629:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  11630:       
1.145     brouard  11631:       /*}*/
1.235     brouard  11632:     } /* End k selection */
1.227     brouard  11633: 
                   11634:     printf("done State-specific expectancies\n");fflush(stdout);
                   11635:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   11636: 
1.126     brouard  11637:     /*------- Variance of period (stable) prevalence------*/   
1.227     brouard  11638:     
1.201     brouard  11639:     strcpy(fileresvpl,"VPL_");
                   11640:     strcat(fileresvpl,fileresu);
1.126     brouard  11641:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   11642:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   11643:       exit(0);
                   11644:     }
1.208     brouard  11645:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   11646:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.227     brouard  11647:     
1.145     brouard  11648:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   11649:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
1.227     brouard  11650:     
1.235     brouard  11651:     i1=pow(2,cptcoveff);
                   11652:     if (cptcovn < 1){i1=1;}
                   11653: 
                   11654:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   11655:     for(k=1; k<=i1;k++){
1.253     brouard  11656:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  11657:        continue;
1.227     brouard  11658:       fprintf(ficresvpl,"\n#****** ");
                   11659:       printf("\n#****** ");
                   11660:       fprintf(ficlog,"\n#****** ");
                   11661:       for(j=1;j<=cptcoveff;j++) {
                   11662:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11663:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11664:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   11665:       }
1.235     brouard  11666:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   11667:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11668:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11669:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   11670:       }        
1.227     brouard  11671:       fprintf(ficresvpl,"******\n");
                   11672:       printf("******\n");
                   11673:       fprintf(ficlog,"******\n");
                   11674:       
                   11675:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   11676:       oldm=oldms;savm=savms;
1.235     brouard  11677:       varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart, nres);
1.227     brouard  11678:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
1.145     brouard  11679:       /*}*/
1.126     brouard  11680:     }
1.227     brouard  11681:     
1.126     brouard  11682:     fclose(ficresvpl);
1.208     brouard  11683:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   11684:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
1.227     brouard  11685:     
                   11686:     free_vector(weight,1,n);
                   11687:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   11688:     free_imatrix(s,1,maxwav+1,1,n);
                   11689:     free_matrix(anint,1,maxwav,1,n); 
                   11690:     free_matrix(mint,1,maxwav,1,n);
                   11691:     free_ivector(cod,1,n);
                   11692:     free_ivector(tab,1,NCOVMAX);
                   11693:     fclose(ficresstdeij);
                   11694:     fclose(ficrescveij);
                   11695:     fclose(ficresvij);
                   11696:     fclose(ficrest);
                   11697:     fclose(ficpar);
                   11698:     
                   11699:     
1.126     brouard  11700:     /*---------- End : free ----------------*/
1.219     brouard  11701:     if (mobilav!=0 ||mobilavproj !=0)
                   11702:       free_ma3x(mobaverages,1, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
1.218     brouard  11703:     free_ma3x(probs,1,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  11704:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   11705:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  11706:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  11707:   /* endfree:*/
                   11708:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11709:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11710:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   11711:   free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
1.233     brouard  11712:   free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
1.227     brouard  11713:   free_matrix(coqvar,1,maxwav,1,n);
                   11714:   free_matrix(covar,0,NCOVMAX,1,n);
                   11715:   free_matrix(matcov,1,npar,1,npar);
                   11716:   free_matrix(hess,1,npar,1,npar);
                   11717:   /*free_vector(delti,1,npar);*/
                   11718:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11719:   free_matrix(agev,1,maxwav,1,imx);
                   11720:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   11721:   
                   11722:   free_ivector(ncodemax,1,NCOVMAX);
                   11723:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   11724:   free_ivector(Dummy,-1,NCOVMAX);
                   11725:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  11726:   free_ivector(DummyV,1,NCOVMAX);
                   11727:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  11728:   free_ivector(Typevar,-1,NCOVMAX);
                   11729:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  11730:   free_ivector(TvarsQ,1,NCOVMAX);
                   11731:   free_ivector(TvarsQind,1,NCOVMAX);
                   11732:   free_ivector(TvarsD,1,NCOVMAX);
                   11733:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  11734:   free_ivector(TvarFD,1,NCOVMAX);
                   11735:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  11736:   free_ivector(TvarF,1,NCOVMAX);
                   11737:   free_ivector(TvarFind,1,NCOVMAX);
                   11738:   free_ivector(TvarV,1,NCOVMAX);
                   11739:   free_ivector(TvarVind,1,NCOVMAX);
                   11740:   free_ivector(TvarA,1,NCOVMAX);
                   11741:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  11742:   free_ivector(TvarFQ,1,NCOVMAX);
                   11743:   free_ivector(TvarFQind,1,NCOVMAX);
                   11744:   free_ivector(TvarVD,1,NCOVMAX);
                   11745:   free_ivector(TvarVDind,1,NCOVMAX);
                   11746:   free_ivector(TvarVQ,1,NCOVMAX);
                   11747:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  11748:   free_ivector(Tvarsel,1,NCOVMAX);
                   11749:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  11750:   free_ivector(Tposprod,1,NCOVMAX);
                   11751:   free_ivector(Tprod,1,NCOVMAX);
                   11752:   free_ivector(Tvaraff,1,NCOVMAX);
                   11753:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   11754:   free_ivector(Tage,1,NCOVMAX);
                   11755:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  11756:   free_ivector(TmodelInvind,1,NCOVMAX);
                   11757:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  11758:   
                   11759:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   11760:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  11761:   fflush(fichtm);
                   11762:   fflush(ficgp);
                   11763:   
1.227     brouard  11764:   
1.126     brouard  11765:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  11766:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   11767:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  11768:   }else{
                   11769:     printf("End of Imach\n");
                   11770:     fprintf(ficlog,"End of Imach\n");
                   11771:   }
                   11772:   printf("See log file on %s\n",filelog);
                   11773:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  11774:   /*(void) gettimeofday(&end_time,&tzp);*/
                   11775:   rend_time = time(NULL);  
                   11776:   end_time = *localtime(&rend_time);
                   11777:   /* tml = *localtime(&end_time.tm_sec); */
                   11778:   strcpy(strtend,asctime(&end_time));
1.126     brouard  11779:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   11780:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  11781:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  11782:   
1.157     brouard  11783:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   11784:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   11785:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  11786:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   11787: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   11788:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11789:   fclose(fichtm);
                   11790:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   11791:   fclose(fichtmcov);
                   11792:   fclose(ficgp);
                   11793:   fclose(ficlog);
                   11794:   /*------ End -----------*/
1.227     brouard  11795:   
                   11796:   
                   11797:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  11798: #ifdef WIN32
1.227     brouard  11799:   if (_chdir(pathcd) != 0)
                   11800:     printf("Can't move to directory %s!\n",path);
                   11801:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  11802: #else
1.227     brouard  11803:     if(chdir(pathcd) != 0)
                   11804:       printf("Can't move to directory %s!\n", path);
                   11805:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  11806: #endif 
1.126     brouard  11807:     printf("Current directory %s!\n",pathcd);
                   11808:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   11809:   sprintf(plotcmd,"gnuplot");
1.157     brouard  11810: #ifdef _WIN32
1.126     brouard  11811:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   11812: #endif
                   11813:   if(!stat(plotcmd,&info)){
1.158     brouard  11814:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11815:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  11816:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  11817:     }else
                   11818:       strcpy(pplotcmd,plotcmd);
1.157     brouard  11819: #ifdef __unix
1.126     brouard  11820:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   11821:     if(!stat(plotcmd,&info)){
1.158     brouard  11822:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  11823:     }else
                   11824:       strcpy(pplotcmd,plotcmd);
                   11825: #endif
                   11826:   }else
                   11827:     strcpy(pplotcmd,plotcmd);
                   11828:   
                   11829:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  11830:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  11831:   
1.126     brouard  11832:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  11833:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  11834:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  11835:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  11836:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  11837:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  11838:   }
1.158     brouard  11839:   printf(" Successful, please wait...");
1.126     brouard  11840:   while (z[0] != 'q') {
                   11841:     /* chdir(path); */
1.154     brouard  11842:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  11843:     scanf("%s",z);
                   11844: /*     if (z[0] == 'c') system("./imach"); */
                   11845:     if (z[0] == 'e') {
1.158     brouard  11846: #ifdef __APPLE__
1.152     brouard  11847:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  11848: #elif __linux
                   11849:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  11850: #else
1.152     brouard  11851:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  11852: #endif
                   11853:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   11854:       system(pplotcmd);
1.126     brouard  11855:     }
                   11856:     else if (z[0] == 'g') system(plotcmd);
                   11857:     else if (z[0] == 'q') exit(0);
                   11858:   }
1.227     brouard  11859: end:
1.126     brouard  11860:   while (z[0] != 'q') {
1.195     brouard  11861:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  11862:     scanf("%s",z);
                   11863:   }
                   11864: }

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