Annotation of imach/src/imach.c, revision 1.269

1.269   ! brouard     1: /* $Id: imach.c,v 1.268 2017/05/18 20:09:32 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.269   ! brouard     4:   Revision 1.268  2017/05/18 20:09:32  brouard
        !             5:   Summary: backprojection and confidence intervals of backprevalence
        !             6: 
1.268     brouard     7:   Revision 1.267  2017/05/13 10:25:05  brouard
                      8:   Summary: temporary save for backprojection
                      9: 
1.267     brouard    10:   Revision 1.266  2017/05/13 07:26:12  brouard
                     11:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     12: 
1.266     brouard    13:   Revision 1.265  2017/04/26 16:22:11  brouard
                     14:   Summary: imach 0.99r13 Some bugs fixed
                     15: 
1.265     brouard    16:   Revision 1.264  2017/04/26 06:01:29  brouard
                     17:   Summary: Labels in graphs
                     18: 
1.264     brouard    19:   Revision 1.263  2017/04/24 15:23:15  brouard
                     20:   Summary: to save
                     21: 
1.263     brouard    22:   Revision 1.262  2017/04/18 16:48:12  brouard
                     23:   *** empty log message ***
                     24: 
1.262     brouard    25:   Revision 1.261  2017/04/05 10:14:09  brouard
                     26:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     27: 
1.261     brouard    28:   Revision 1.260  2017/04/04 17:46:59  brouard
                     29:   Summary: Gnuplot indexations fixed (humm)
                     30: 
1.260     brouard    31:   Revision 1.259  2017/04/04 13:01:16  brouard
                     32:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     33: 
1.259     brouard    34:   Revision 1.258  2017/04/03 10:17:47  brouard
                     35:   Summary: Version 0.99r12
                     36: 
                     37:   Some cleanings, conformed with updated documentation.
                     38: 
1.258     brouard    39:   Revision 1.257  2017/03/29 16:53:30  brouard
                     40:   Summary: Temp
                     41: 
1.257     brouard    42:   Revision 1.256  2017/03/27 05:50:23  brouard
                     43:   Summary: Temporary
                     44: 
1.256     brouard    45:   Revision 1.255  2017/03/08 16:02:28  brouard
                     46:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     47: 
1.255     brouard    48:   Revision 1.254  2017/03/08 07:13:00  brouard
                     49:   Summary: Fixing data parameter line
                     50: 
1.254     brouard    51:   Revision 1.253  2016/12/15 11:59:41  brouard
                     52:   Summary: 0.99 in progress
                     53: 
1.253     brouard    54:   Revision 1.252  2016/09/15 21:15:37  brouard
                     55:   *** empty log message ***
                     56: 
1.252     brouard    57:   Revision 1.251  2016/09/15 15:01:13  brouard
                     58:   Summary: not working
                     59: 
1.251     brouard    60:   Revision 1.250  2016/09/08 16:07:27  brouard
                     61:   Summary: continue
                     62: 
1.250     brouard    63:   Revision 1.249  2016/09/07 17:14:18  brouard
                     64:   Summary: Starting values from frequencies
                     65: 
1.249     brouard    66:   Revision 1.248  2016/09/07 14:10:18  brouard
                     67:   *** empty log message ***
                     68: 
1.248     brouard    69:   Revision 1.247  2016/09/02 11:11:21  brouard
                     70:   *** empty log message ***
                     71: 
1.247     brouard    72:   Revision 1.246  2016/09/02 08:49:22  brouard
                     73:   *** empty log message ***
                     74: 
1.246     brouard    75:   Revision 1.245  2016/09/02 07:25:01  brouard
                     76:   *** empty log message ***
                     77: 
1.245     brouard    78:   Revision 1.244  2016/09/02 07:17:34  brouard
                     79:   *** empty log message ***
                     80: 
1.244     brouard    81:   Revision 1.243  2016/09/02 06:45:35  brouard
                     82:   *** empty log message ***
                     83: 
1.243     brouard    84:   Revision 1.242  2016/08/30 15:01:20  brouard
                     85:   Summary: Fixing a lots
                     86: 
1.242     brouard    87:   Revision 1.241  2016/08/29 17:17:25  brouard
                     88:   Summary: gnuplot problem in Back projection to fix
                     89: 
1.241     brouard    90:   Revision 1.240  2016/08/29 07:53:18  brouard
                     91:   Summary: Better
                     92: 
1.240     brouard    93:   Revision 1.239  2016/08/26 15:51:03  brouard
                     94:   Summary: Improvement in Powell output in order to copy and paste
                     95: 
                     96:   Author:
                     97: 
1.239     brouard    98:   Revision 1.238  2016/08/26 14:23:35  brouard
                     99:   Summary: Starting tests of 0.99
                    100: 
1.238     brouard   101:   Revision 1.237  2016/08/26 09:20:19  brouard
                    102:   Summary: to valgrind
                    103: 
1.237     brouard   104:   Revision 1.236  2016/08/25 10:50:18  brouard
                    105:   *** empty log message ***
                    106: 
1.236     brouard   107:   Revision 1.235  2016/08/25 06:59:23  brouard
                    108:   *** empty log message ***
                    109: 
1.235     brouard   110:   Revision 1.234  2016/08/23 16:51:20  brouard
                    111:   *** empty log message ***
                    112: 
1.234     brouard   113:   Revision 1.233  2016/08/23 07:40:50  brouard
                    114:   Summary: not working
                    115: 
1.233     brouard   116:   Revision 1.232  2016/08/22 14:20:21  brouard
                    117:   Summary: not working
                    118: 
1.232     brouard   119:   Revision 1.231  2016/08/22 07:17:15  brouard
                    120:   Summary: not working
                    121: 
1.231     brouard   122:   Revision 1.230  2016/08/22 06:55:53  brouard
                    123:   Summary: Not working
                    124: 
1.230     brouard   125:   Revision 1.229  2016/07/23 09:45:53  brouard
                    126:   Summary: Completing for func too
                    127: 
1.229     brouard   128:   Revision 1.228  2016/07/22 17:45:30  brouard
                    129:   Summary: Fixing some arrays, still debugging
                    130: 
1.227     brouard   131:   Revision 1.226  2016/07/12 18:42:34  brouard
                    132:   Summary: temp
                    133: 
1.226     brouard   134:   Revision 1.225  2016/07/12 08:40:03  brouard
                    135:   Summary: saving but not running
                    136: 
1.225     brouard   137:   Revision 1.224  2016/07/01 13:16:01  brouard
                    138:   Summary: Fixes
                    139: 
1.224     brouard   140:   Revision 1.223  2016/02/19 09:23:35  brouard
                    141:   Summary: temporary
                    142: 
1.223     brouard   143:   Revision 1.222  2016/02/17 08:14:50  brouard
                    144:   Summary: Probably last 0.98 stable version 0.98r6
                    145: 
1.222     brouard   146:   Revision 1.221  2016/02/15 23:35:36  brouard
                    147:   Summary: minor bug
                    148: 
1.220     brouard   149:   Revision 1.219  2016/02/15 00:48:12  brouard
                    150:   *** empty log message ***
                    151: 
1.219     brouard   152:   Revision 1.218  2016/02/12 11:29:23  brouard
                    153:   Summary: 0.99 Back projections
                    154: 
1.218     brouard   155:   Revision 1.217  2015/12/23 17:18:31  brouard
                    156:   Summary: Experimental backcast
                    157: 
1.217     brouard   158:   Revision 1.216  2015/12/18 17:32:11  brouard
                    159:   Summary: 0.98r4 Warning and status=-2
                    160: 
                    161:   Version 0.98r4 is now:
                    162:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    163:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    164:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    165: 
1.216     brouard   166:   Revision 1.215  2015/12/16 08:52:24  brouard
                    167:   Summary: 0.98r4 working
                    168: 
1.215     brouard   169:   Revision 1.214  2015/12/16 06:57:54  brouard
                    170:   Summary: temporary not working
                    171: 
1.214     brouard   172:   Revision 1.213  2015/12/11 18:22:17  brouard
                    173:   Summary: 0.98r4
                    174: 
1.213     brouard   175:   Revision 1.212  2015/11/21 12:47:24  brouard
                    176:   Summary: minor typo
                    177: 
1.212     brouard   178:   Revision 1.211  2015/11/21 12:41:11  brouard
                    179:   Summary: 0.98r3 with some graph of projected cross-sectional
                    180: 
                    181:   Author: Nicolas Brouard
                    182: 
1.211     brouard   183:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   184:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   185:   Summary: Adding ftolpl parameter
                    186:   Author: N Brouard
                    187: 
                    188:   We had difficulties to get smoothed confidence intervals. It was due
                    189:   to the period prevalence which wasn't computed accurately. The inner
                    190:   parameter ftolpl is now an outer parameter of the .imach parameter
                    191:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    192:   computation are long.
                    193: 
1.209     brouard   194:   Revision 1.208  2015/11/17 14:31:57  brouard
                    195:   Summary: temporary
                    196: 
1.208     brouard   197:   Revision 1.207  2015/10/27 17:36:57  brouard
                    198:   *** empty log message ***
                    199: 
1.207     brouard   200:   Revision 1.206  2015/10/24 07:14:11  brouard
                    201:   *** empty log message ***
                    202: 
1.206     brouard   203:   Revision 1.205  2015/10/23 15:50:53  brouard
                    204:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    205: 
1.205     brouard   206:   Revision 1.204  2015/10/01 16:20:26  brouard
                    207:   Summary: Some new graphs of contribution to likelihood
                    208: 
1.204     brouard   209:   Revision 1.203  2015/09/30 17:45:14  brouard
                    210:   Summary: looking at better estimation of the hessian
                    211: 
                    212:   Also a better criteria for convergence to the period prevalence And
                    213:   therefore adding the number of years needed to converge. (The
                    214:   prevalence in any alive state shold sum to one
                    215: 
1.203     brouard   216:   Revision 1.202  2015/09/22 19:45:16  brouard
                    217:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    218: 
1.202     brouard   219:   Revision 1.201  2015/09/15 17:34:58  brouard
                    220:   Summary: 0.98r0
                    221: 
                    222:   - Some new graphs like suvival functions
                    223:   - Some bugs fixed like model=1+age+V2.
                    224: 
1.201     brouard   225:   Revision 1.200  2015/09/09 16:53:55  brouard
                    226:   Summary: Big bug thanks to Flavia
                    227: 
                    228:   Even model=1+age+V2. did not work anymore
                    229: 
1.200     brouard   230:   Revision 1.199  2015/09/07 14:09:23  brouard
                    231:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    232: 
1.199     brouard   233:   Revision 1.198  2015/09/03 07:14:39  brouard
                    234:   Summary: 0.98q5 Flavia
                    235: 
1.198     brouard   236:   Revision 1.197  2015/09/01 18:24:39  brouard
                    237:   *** empty log message ***
                    238: 
1.197     brouard   239:   Revision 1.196  2015/08/18 23:17:52  brouard
                    240:   Summary: 0.98q5
                    241: 
1.196     brouard   242:   Revision 1.195  2015/08/18 16:28:39  brouard
                    243:   Summary: Adding a hack for testing purpose
                    244: 
                    245:   After reading the title, ftol and model lines, if the comment line has
                    246:   a q, starting with #q, the answer at the end of the run is quit. It
                    247:   permits to run test files in batch with ctest. The former workaround was
                    248:   $ echo q | imach foo.imach
                    249: 
1.195     brouard   250:   Revision 1.194  2015/08/18 13:32:00  brouard
                    251:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    252: 
1.194     brouard   253:   Revision 1.193  2015/08/04 07:17:42  brouard
                    254:   Summary: 0.98q4
                    255: 
1.193     brouard   256:   Revision 1.192  2015/07/16 16:49:02  brouard
                    257:   Summary: Fixing some outputs
                    258: 
1.192     brouard   259:   Revision 1.191  2015/07/14 10:00:33  brouard
                    260:   Summary: Some fixes
                    261: 
1.191     brouard   262:   Revision 1.190  2015/05/05 08:51:13  brouard
                    263:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    264: 
                    265:   Fix 1+age+.
                    266: 
1.190     brouard   267:   Revision 1.189  2015/04/30 14:45:16  brouard
                    268:   Summary: 0.98q2
                    269: 
1.189     brouard   270:   Revision 1.188  2015/04/30 08:27:53  brouard
                    271:   *** empty log message ***
                    272: 
1.188     brouard   273:   Revision 1.187  2015/04/29 09:11:15  brouard
                    274:   *** empty log message ***
                    275: 
1.187     brouard   276:   Revision 1.186  2015/04/23 12:01:52  brouard
                    277:   Summary: V1*age is working now, version 0.98q1
                    278: 
                    279:   Some codes had been disabled in order to simplify and Vn*age was
                    280:   working in the optimization phase, ie, giving correct MLE parameters,
                    281:   but, as usual, outputs were not correct and program core dumped.
                    282: 
1.186     brouard   283:   Revision 1.185  2015/03/11 13:26:42  brouard
                    284:   Summary: Inclusion of compile and links command line for Intel Compiler
                    285: 
1.185     brouard   286:   Revision 1.184  2015/03/11 11:52:39  brouard
                    287:   Summary: Back from Windows 8. Intel Compiler
                    288: 
1.184     brouard   289:   Revision 1.183  2015/03/10 20:34:32  brouard
                    290:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    291: 
                    292:   We use directest instead of original Powell test; probably no
                    293:   incidence on the results, but better justifications;
                    294:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    295:   wrong results.
                    296: 
1.183     brouard   297:   Revision 1.182  2015/02/12 08:19:57  brouard
                    298:   Summary: Trying to keep directest which seems simpler and more general
                    299:   Author: Nicolas Brouard
                    300: 
1.182     brouard   301:   Revision 1.181  2015/02/11 23:22:24  brouard
                    302:   Summary: Comments on Powell added
                    303: 
                    304:   Author:
                    305: 
1.181     brouard   306:   Revision 1.180  2015/02/11 17:33:45  brouard
                    307:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    308: 
1.180     brouard   309:   Revision 1.179  2015/01/04 09:57:06  brouard
                    310:   Summary: back to OS/X
                    311: 
1.179     brouard   312:   Revision 1.178  2015/01/04 09:35:48  brouard
                    313:   *** empty log message ***
                    314: 
1.178     brouard   315:   Revision 1.177  2015/01/03 18:40:56  brouard
                    316:   Summary: Still testing ilc32 on OSX
                    317: 
1.177     brouard   318:   Revision 1.176  2015/01/03 16:45:04  brouard
                    319:   *** empty log message ***
                    320: 
1.176     brouard   321:   Revision 1.175  2015/01/03 16:33:42  brouard
                    322:   *** empty log message ***
                    323: 
1.175     brouard   324:   Revision 1.174  2015/01/03 16:15:49  brouard
                    325:   Summary: Still in cross-compilation
                    326: 
1.174     brouard   327:   Revision 1.173  2015/01/03 12:06:26  brouard
                    328:   Summary: trying to detect cross-compilation
                    329: 
1.173     brouard   330:   Revision 1.172  2014/12/27 12:07:47  brouard
                    331:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    332: 
1.172     brouard   333:   Revision 1.171  2014/12/23 13:26:59  brouard
                    334:   Summary: Back from Visual C
                    335: 
                    336:   Still problem with utsname.h on Windows
                    337: 
1.171     brouard   338:   Revision 1.170  2014/12/23 11:17:12  brouard
                    339:   Summary: Cleaning some \%% back to %%
                    340: 
                    341:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    342: 
1.170     brouard   343:   Revision 1.169  2014/12/22 23:08:31  brouard
                    344:   Summary: 0.98p
                    345: 
                    346:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    347: 
1.169     brouard   348:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   349:   Summary: update
1.169     brouard   350: 
1.168     brouard   351:   Revision 1.167  2014/12/22 13:50:56  brouard
                    352:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    353: 
                    354:   Testing on Linux 64
                    355: 
1.167     brouard   356:   Revision 1.166  2014/12/22 11:40:47  brouard
                    357:   *** empty log message ***
                    358: 
1.166     brouard   359:   Revision 1.165  2014/12/16 11:20:36  brouard
                    360:   Summary: After compiling on Visual C
                    361: 
                    362:   * imach.c (Module): Merging 1.61 to 1.162
                    363: 
1.165     brouard   364:   Revision 1.164  2014/12/16 10:52:11  brouard
                    365:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    366: 
                    367:   * imach.c (Module): Merging 1.61 to 1.162
                    368: 
1.164     brouard   369:   Revision 1.163  2014/12/16 10:30:11  brouard
                    370:   * imach.c (Module): Merging 1.61 to 1.162
                    371: 
1.163     brouard   372:   Revision 1.162  2014/09/25 11:43:39  brouard
                    373:   Summary: temporary backup 0.99!
                    374: 
1.162     brouard   375:   Revision 1.1  2014/09/16 11:06:58  brouard
                    376:   Summary: With some code (wrong) for nlopt
                    377: 
                    378:   Author:
                    379: 
                    380:   Revision 1.161  2014/09/15 20:41:41  brouard
                    381:   Summary: Problem with macro SQR on Intel compiler
                    382: 
1.161     brouard   383:   Revision 1.160  2014/09/02 09:24:05  brouard
                    384:   *** empty log message ***
                    385: 
1.160     brouard   386:   Revision 1.159  2014/09/01 10:34:10  brouard
                    387:   Summary: WIN32
                    388:   Author: Brouard
                    389: 
1.159     brouard   390:   Revision 1.158  2014/08/27 17:11:51  brouard
                    391:   *** empty log message ***
                    392: 
1.158     brouard   393:   Revision 1.157  2014/08/27 16:26:55  brouard
                    394:   Summary: Preparing windows Visual studio version
                    395:   Author: Brouard
                    396: 
                    397:   In order to compile on Visual studio, time.h is now correct and time_t
                    398:   and tm struct should be used. difftime should be used but sometimes I
                    399:   just make the differences in raw time format (time(&now).
                    400:   Trying to suppress #ifdef LINUX
                    401:   Add xdg-open for __linux in order to open default browser.
                    402: 
1.157     brouard   403:   Revision 1.156  2014/08/25 20:10:10  brouard
                    404:   *** empty log message ***
                    405: 
1.156     brouard   406:   Revision 1.155  2014/08/25 18:32:34  brouard
                    407:   Summary: New compile, minor changes
                    408:   Author: Brouard
                    409: 
1.155     brouard   410:   Revision 1.154  2014/06/20 17:32:08  brouard
                    411:   Summary: Outputs now all graphs of convergence to period prevalence
                    412: 
1.154     brouard   413:   Revision 1.153  2014/06/20 16:45:46  brouard
                    414:   Summary: If 3 live state, convergence to period prevalence on same graph
                    415:   Author: Brouard
                    416: 
1.153     brouard   417:   Revision 1.152  2014/06/18 17:54:09  brouard
                    418:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    419: 
1.152     brouard   420:   Revision 1.151  2014/06/18 16:43:30  brouard
                    421:   *** empty log message ***
                    422: 
1.151     brouard   423:   Revision 1.150  2014/06/18 16:42:35  brouard
                    424:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    425:   Author: brouard
                    426: 
1.150     brouard   427:   Revision 1.149  2014/06/18 15:51:14  brouard
                    428:   Summary: Some fixes in parameter files errors
                    429:   Author: Nicolas Brouard
                    430: 
1.149     brouard   431:   Revision 1.148  2014/06/17 17:38:48  brouard
                    432:   Summary: Nothing new
                    433:   Author: Brouard
                    434: 
                    435:   Just a new packaging for OS/X version 0.98nS
                    436: 
1.148     brouard   437:   Revision 1.147  2014/06/16 10:33:11  brouard
                    438:   *** empty log message ***
                    439: 
1.147     brouard   440:   Revision 1.146  2014/06/16 10:20:28  brouard
                    441:   Summary: Merge
                    442:   Author: Brouard
                    443: 
                    444:   Merge, before building revised version.
                    445: 
1.146     brouard   446:   Revision 1.145  2014/06/10 21:23:15  brouard
                    447:   Summary: Debugging with valgrind
                    448:   Author: Nicolas Brouard
                    449: 
                    450:   Lot of changes in order to output the results with some covariates
                    451:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    452:   improve the code.
                    453:   No more memory valgrind error but a lot has to be done in order to
                    454:   continue the work of splitting the code into subroutines.
                    455:   Also, decodemodel has been improved. Tricode is still not
                    456:   optimal. nbcode should be improved. Documentation has been added in
                    457:   the source code.
                    458: 
1.144     brouard   459:   Revision 1.143  2014/01/26 09:45:38  brouard
                    460:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    461: 
                    462:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    463:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    464: 
1.143     brouard   465:   Revision 1.142  2014/01/26 03:57:36  brouard
                    466:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    467: 
                    468:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    469: 
1.142     brouard   470:   Revision 1.141  2014/01/26 02:42:01  brouard
                    471:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    472: 
1.141     brouard   473:   Revision 1.140  2011/09/02 10:37:54  brouard
                    474:   Summary: times.h is ok with mingw32 now.
                    475: 
1.140     brouard   476:   Revision 1.139  2010/06/14 07:50:17  brouard
                    477:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    478:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    479: 
1.139     brouard   480:   Revision 1.138  2010/04/30 18:19:40  brouard
                    481:   *** empty log message ***
                    482: 
1.138     brouard   483:   Revision 1.137  2010/04/29 18:11:38  brouard
                    484:   (Module): Checking covariates for more complex models
                    485:   than V1+V2. A lot of change to be done. Unstable.
                    486: 
1.137     brouard   487:   Revision 1.136  2010/04/26 20:30:53  brouard
                    488:   (Module): merging some libgsl code. Fixing computation
                    489:   of likelione (using inter/intrapolation if mle = 0) in order to
                    490:   get same likelihood as if mle=1.
                    491:   Some cleaning of code and comments added.
                    492: 
1.136     brouard   493:   Revision 1.135  2009/10/29 15:33:14  brouard
                    494:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    495: 
1.135     brouard   496:   Revision 1.134  2009/10/29 13:18:53  brouard
                    497:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    498: 
1.134     brouard   499:   Revision 1.133  2009/07/06 10:21:25  brouard
                    500:   just nforces
                    501: 
1.133     brouard   502:   Revision 1.132  2009/07/06 08:22:05  brouard
                    503:   Many tings
                    504: 
1.132     brouard   505:   Revision 1.131  2009/06/20 16:22:47  brouard
                    506:   Some dimensions resccaled
                    507: 
1.131     brouard   508:   Revision 1.130  2009/05/26 06:44:34  brouard
                    509:   (Module): Max Covariate is now set to 20 instead of 8. A
                    510:   lot of cleaning with variables initialized to 0. Trying to make
                    511:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    512: 
1.130     brouard   513:   Revision 1.129  2007/08/31 13:49:27  lievre
                    514:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    515: 
1.129     lievre    516:   Revision 1.128  2006/06/30 13:02:05  brouard
                    517:   (Module): Clarifications on computing e.j
                    518: 
1.128     brouard   519:   Revision 1.127  2006/04/28 18:11:50  brouard
                    520:   (Module): Yes the sum of survivors was wrong since
                    521:   imach-114 because nhstepm was no more computed in the age
                    522:   loop. Now we define nhstepma in the age loop.
                    523:   (Module): In order to speed up (in case of numerous covariates) we
                    524:   compute health expectancies (without variances) in a first step
                    525:   and then all the health expectancies with variances or standard
                    526:   deviation (needs data from the Hessian matrices) which slows the
                    527:   computation.
                    528:   In the future we should be able to stop the program is only health
                    529:   expectancies and graph are needed without standard deviations.
                    530: 
1.127     brouard   531:   Revision 1.126  2006/04/28 17:23:28  brouard
                    532:   (Module): Yes the sum of survivors was wrong since
                    533:   imach-114 because nhstepm was no more computed in the age
                    534:   loop. Now we define nhstepma in the age loop.
                    535:   Version 0.98h
                    536: 
1.126     brouard   537:   Revision 1.125  2006/04/04 15:20:31  lievre
                    538:   Errors in calculation of health expectancies. Age was not initialized.
                    539:   Forecasting file added.
                    540: 
                    541:   Revision 1.124  2006/03/22 17:13:53  lievre
                    542:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    543:   The log-likelihood is printed in the log file
                    544: 
                    545:   Revision 1.123  2006/03/20 10:52:43  brouard
                    546:   * imach.c (Module): <title> changed, corresponds to .htm file
                    547:   name. <head> headers where missing.
                    548: 
                    549:   * imach.c (Module): Weights can have a decimal point as for
                    550:   English (a comma might work with a correct LC_NUMERIC environment,
                    551:   otherwise the weight is truncated).
                    552:   Modification of warning when the covariates values are not 0 or
                    553:   1.
                    554:   Version 0.98g
                    555: 
                    556:   Revision 1.122  2006/03/20 09:45:41  brouard
                    557:   (Module): Weights can have a decimal point as for
                    558:   English (a comma might work with a correct LC_NUMERIC environment,
                    559:   otherwise the weight is truncated).
                    560:   Modification of warning when the covariates values are not 0 or
                    561:   1.
                    562:   Version 0.98g
                    563: 
                    564:   Revision 1.121  2006/03/16 17:45:01  lievre
                    565:   * imach.c (Module): Comments concerning covariates added
                    566: 
                    567:   * imach.c (Module): refinements in the computation of lli if
                    568:   status=-2 in order to have more reliable computation if stepm is
                    569:   not 1 month. Version 0.98f
                    570: 
                    571:   Revision 1.120  2006/03/16 15:10:38  lievre
                    572:   (Module): refinements in the computation of lli if
                    573:   status=-2 in order to have more reliable computation if stepm is
                    574:   not 1 month. Version 0.98f
                    575: 
                    576:   Revision 1.119  2006/03/15 17:42:26  brouard
                    577:   (Module): Bug if status = -2, the loglikelihood was
                    578:   computed as likelihood omitting the logarithm. Version O.98e
                    579: 
                    580:   Revision 1.118  2006/03/14 18:20:07  brouard
                    581:   (Module): varevsij Comments added explaining the second
                    582:   table of variances if popbased=1 .
                    583:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    584:   (Module): Function pstamp added
                    585:   (Module): Version 0.98d
                    586: 
                    587:   Revision 1.117  2006/03/14 17:16:22  brouard
                    588:   (Module): varevsij Comments added explaining the second
                    589:   table of variances if popbased=1 .
                    590:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    591:   (Module): Function pstamp added
                    592:   (Module): Version 0.98d
                    593: 
                    594:   Revision 1.116  2006/03/06 10:29:27  brouard
                    595:   (Module): Variance-covariance wrong links and
                    596:   varian-covariance of ej. is needed (Saito).
                    597: 
                    598:   Revision 1.115  2006/02/27 12:17:45  brouard
                    599:   (Module): One freematrix added in mlikeli! 0.98c
                    600: 
                    601:   Revision 1.114  2006/02/26 12:57:58  brouard
                    602:   (Module): Some improvements in processing parameter
                    603:   filename with strsep.
                    604: 
                    605:   Revision 1.113  2006/02/24 14:20:24  brouard
                    606:   (Module): Memory leaks checks with valgrind and:
                    607:   datafile was not closed, some imatrix were not freed and on matrix
                    608:   allocation too.
                    609: 
                    610:   Revision 1.112  2006/01/30 09:55:26  brouard
                    611:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    612: 
                    613:   Revision 1.111  2006/01/25 20:38:18  brouard
                    614:   (Module): Lots of cleaning and bugs added (Gompertz)
                    615:   (Module): Comments can be added in data file. Missing date values
                    616:   can be a simple dot '.'.
                    617: 
                    618:   Revision 1.110  2006/01/25 00:51:50  brouard
                    619:   (Module): Lots of cleaning and bugs added (Gompertz)
                    620: 
                    621:   Revision 1.109  2006/01/24 19:37:15  brouard
                    622:   (Module): Comments (lines starting with a #) are allowed in data.
                    623: 
                    624:   Revision 1.108  2006/01/19 18:05:42  lievre
                    625:   Gnuplot problem appeared...
                    626:   To be fixed
                    627: 
                    628:   Revision 1.107  2006/01/19 16:20:37  brouard
                    629:   Test existence of gnuplot in imach path
                    630: 
                    631:   Revision 1.106  2006/01/19 13:24:36  brouard
                    632:   Some cleaning and links added in html output
                    633: 
                    634:   Revision 1.105  2006/01/05 20:23:19  lievre
                    635:   *** empty log message ***
                    636: 
                    637:   Revision 1.104  2005/09/30 16:11:43  lievre
                    638:   (Module): sump fixed, loop imx fixed, and simplifications.
                    639:   (Module): If the status is missing at the last wave but we know
                    640:   that the person is alive, then we can code his/her status as -2
                    641:   (instead of missing=-1 in earlier versions) and his/her
                    642:   contributions to the likelihood is 1 - Prob of dying from last
                    643:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    644:   the healthy state at last known wave). Version is 0.98
                    645: 
                    646:   Revision 1.103  2005/09/30 15:54:49  lievre
                    647:   (Module): sump fixed, loop imx fixed, and simplifications.
                    648: 
                    649:   Revision 1.102  2004/09/15 17:31:30  brouard
                    650:   Add the possibility to read data file including tab characters.
                    651: 
                    652:   Revision 1.101  2004/09/15 10:38:38  brouard
                    653:   Fix on curr_time
                    654: 
                    655:   Revision 1.100  2004/07/12 18:29:06  brouard
                    656:   Add version for Mac OS X. Just define UNIX in Makefile
                    657: 
                    658:   Revision 1.99  2004/06/05 08:57:40  brouard
                    659:   *** empty log message ***
                    660: 
                    661:   Revision 1.98  2004/05/16 15:05:56  brouard
                    662:   New version 0.97 . First attempt to estimate force of mortality
                    663:   directly from the data i.e. without the need of knowing the health
                    664:   state at each age, but using a Gompertz model: log u =a + b*age .
                    665:   This is the basic analysis of mortality and should be done before any
                    666:   other analysis, in order to test if the mortality estimated from the
                    667:   cross-longitudinal survey is different from the mortality estimated
                    668:   from other sources like vital statistic data.
                    669: 
                    670:   The same imach parameter file can be used but the option for mle should be -3.
                    671: 
1.133     brouard   672:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   673:   former routines in order to include the new code within the former code.
                    674: 
                    675:   The output is very simple: only an estimate of the intercept and of
                    676:   the slope with 95% confident intervals.
                    677: 
                    678:   Current limitations:
                    679:   A) Even if you enter covariates, i.e. with the
                    680:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    681:   B) There is no computation of Life Expectancy nor Life Table.
                    682: 
                    683:   Revision 1.97  2004/02/20 13:25:42  lievre
                    684:   Version 0.96d. Population forecasting command line is (temporarily)
                    685:   suppressed.
                    686: 
                    687:   Revision 1.96  2003/07/15 15:38:55  brouard
                    688:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    689:   rewritten within the same printf. Workaround: many printfs.
                    690: 
                    691:   Revision 1.95  2003/07/08 07:54:34  brouard
                    692:   * imach.c (Repository):
                    693:   (Repository): Using imachwizard code to output a more meaningful covariance
                    694:   matrix (cov(a12,c31) instead of numbers.
                    695: 
                    696:   Revision 1.94  2003/06/27 13:00:02  brouard
                    697:   Just cleaning
                    698: 
                    699:   Revision 1.93  2003/06/25 16:33:55  brouard
                    700:   (Module): On windows (cygwin) function asctime_r doesn't
                    701:   exist so I changed back to asctime which exists.
                    702:   (Module): Version 0.96b
                    703: 
                    704:   Revision 1.92  2003/06/25 16:30:45  brouard
                    705:   (Module): On windows (cygwin) function asctime_r doesn't
                    706:   exist so I changed back to asctime which exists.
                    707: 
                    708:   Revision 1.91  2003/06/25 15:30:29  brouard
                    709:   * imach.c (Repository): Duplicated warning errors corrected.
                    710:   (Repository): Elapsed time after each iteration is now output. It
                    711:   helps to forecast when convergence will be reached. Elapsed time
                    712:   is stamped in powell.  We created a new html file for the graphs
                    713:   concerning matrix of covariance. It has extension -cov.htm.
                    714: 
                    715:   Revision 1.90  2003/06/24 12:34:15  brouard
                    716:   (Module): Some bugs corrected for windows. Also, when
                    717:   mle=-1 a template is output in file "or"mypar.txt with the design
                    718:   of the covariance matrix to be input.
                    719: 
                    720:   Revision 1.89  2003/06/24 12:30:52  brouard
                    721:   (Module): Some bugs corrected for windows. Also, when
                    722:   mle=-1 a template is output in file "or"mypar.txt with the design
                    723:   of the covariance matrix to be input.
                    724: 
                    725:   Revision 1.88  2003/06/23 17:54:56  brouard
                    726:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    727: 
                    728:   Revision 1.87  2003/06/18 12:26:01  brouard
                    729:   Version 0.96
                    730: 
                    731:   Revision 1.86  2003/06/17 20:04:08  brouard
                    732:   (Module): Change position of html and gnuplot routines and added
                    733:   routine fileappend.
                    734: 
                    735:   Revision 1.85  2003/06/17 13:12:43  brouard
                    736:   * imach.c (Repository): Check when date of death was earlier that
                    737:   current date of interview. It may happen when the death was just
                    738:   prior to the death. In this case, dh was negative and likelihood
                    739:   was wrong (infinity). We still send an "Error" but patch by
                    740:   assuming that the date of death was just one stepm after the
                    741:   interview.
                    742:   (Repository): Because some people have very long ID (first column)
                    743:   we changed int to long in num[] and we added a new lvector for
                    744:   memory allocation. But we also truncated to 8 characters (left
                    745:   truncation)
                    746:   (Repository): No more line truncation errors.
                    747: 
                    748:   Revision 1.84  2003/06/13 21:44:43  brouard
                    749:   * imach.c (Repository): Replace "freqsummary" at a correct
                    750:   place. It differs from routine "prevalence" which may be called
                    751:   many times. Probs is memory consuming and must be used with
                    752:   parcimony.
                    753:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    754: 
                    755:   Revision 1.83  2003/06/10 13:39:11  lievre
                    756:   *** empty log message ***
                    757: 
                    758:   Revision 1.82  2003/06/05 15:57:20  brouard
                    759:   Add log in  imach.c and  fullversion number is now printed.
                    760: 
                    761: */
                    762: /*
                    763:    Interpolated Markov Chain
                    764: 
                    765:   Short summary of the programme:
                    766:   
1.227     brouard   767:   This program computes Healthy Life Expectancies or State-specific
                    768:   (if states aren't health statuses) Expectancies from
                    769:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    770: 
                    771:   -1- a first survey ("cross") where individuals from different ages
                    772:   are interviewed on their health status or degree of disability (in
                    773:   the case of a health survey which is our main interest)
                    774: 
                    775:   -2- at least a second wave of interviews ("longitudinal") which
                    776:   measure each change (if any) in individual health status.  Health
                    777:   expectancies are computed from the time spent in each health state
                    778:   according to a model. More health states you consider, more time is
                    779:   necessary to reach the Maximum Likelihood of the parameters involved
                    780:   in the model.  The simplest model is the multinomial logistic model
                    781:   where pij is the probability to be observed in state j at the second
                    782:   wave conditional to be observed in state i at the first
                    783:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    784:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    785:   have a more complex model than "constant and age", you should modify
                    786:   the program where the markup *Covariates have to be included here
                    787:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   788:   convergence.
                    789: 
                    790:   The advantage of this computer programme, compared to a simple
                    791:   multinomial logistic model, is clear when the delay between waves is not
                    792:   identical for each individual. Also, if a individual missed an
                    793:   intermediate interview, the information is lost, but taken into
                    794:   account using an interpolation or extrapolation.  
                    795: 
                    796:   hPijx is the probability to be observed in state i at age x+h
                    797:   conditional to the observed state i at age x. The delay 'h' can be
                    798:   split into an exact number (nh*stepm) of unobserved intermediate
                    799:   states. This elementary transition (by month, quarter,
                    800:   semester or year) is modelled as a multinomial logistic.  The hPx
                    801:   matrix is simply the matrix product of nh*stepm elementary matrices
                    802:   and the contribution of each individual to the likelihood is simply
                    803:   hPijx.
                    804: 
                    805:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   806:   of the life expectancies. It also computes the period (stable) prevalence.
                    807: 
                    808: Back prevalence and projections:
1.227     brouard   809: 
                    810:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    811:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    812:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    813:    mobilavproj)
                    814: 
                    815:     Computes the back prevalence limit for any combination of
                    816:     covariate values k at any age between ageminpar and agemaxpar and
                    817:     returns it in **bprlim. In the loops,
                    818: 
                    819:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    820:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    821: 
                    822:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   823:    Computes for any combination of covariates k and any age between bage and fage 
                    824:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    825:                        oldm=oldms;savm=savms;
1.227     brouard   826: 
1.267     brouard   827:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   828:      Computes the transition matrix starting at age 'age' over
                    829:      'nhstepm*hstepm*stepm' months (i.e. until
                    830:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   831:      nhstepm*hstepm matrices. 
                    832: 
                    833:      Returns p3mat[i][j][h] after calling
                    834:      p3mat[i][j][h]=matprod2(newm,
                    835:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    836:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    837:      oldm);
1.226     brouard   838: 
                    839: Important routines
                    840: 
                    841: - func (or funcone), computes logit (pij) distinguishing
                    842:   o fixed variables (single or product dummies or quantitative);
                    843:   o varying variables by:
                    844:    (1) wave (single, product dummies, quantitative), 
                    845:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    846:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    847:        % varying dummy (not done) or quantitative (not done);
                    848: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    849:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    850: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    851:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    852:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   853: 
1.226     brouard   854: 
                    855:   
1.133     brouard   856:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    857:            Institut national d'études démographiques, Paris.
1.126     brouard   858:   This software have been partly granted by Euro-REVES, a concerted action
                    859:   from the European Union.
                    860:   It is copyrighted identically to a GNU software product, ie programme and
                    861:   software can be distributed freely for non commercial use. Latest version
                    862:   can be accessed at http://euroreves.ined.fr/imach .
                    863: 
                    864:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    865:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    866:   
                    867:   **********************************************************************/
                    868: /*
                    869:   main
                    870:   read parameterfile
                    871:   read datafile
                    872:   concatwav
                    873:   freqsummary
                    874:   if (mle >= 1)
                    875:     mlikeli
                    876:   print results files
                    877:   if mle==1 
                    878:      computes hessian
                    879:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    880:       begin-prev-date,...
                    881:   open gnuplot file
                    882:   open html file
1.145     brouard   883:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    884:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    885:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    886:     freexexit2 possible for memory heap.
                    887: 
                    888:   h Pij x                         | pij_nom  ficrestpij
                    889:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    890:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    891:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    892: 
                    893:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    894:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    895:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    896:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    897:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    898: 
1.126     brouard   899:   forecasting if prevfcast==1 prevforecast call prevalence()
                    900:   health expectancies
                    901:   Variance-covariance of DFLE
                    902:   prevalence()
                    903:    movingaverage()
                    904:   varevsij() 
                    905:   if popbased==1 varevsij(,popbased)
                    906:   total life expectancies
                    907:   Variance of period (stable) prevalence
                    908:  end
                    909: */
                    910: 
1.187     brouard   911: /* #define DEBUG */
                    912: /* #define DEBUGBRENT */
1.203     brouard   913: /* #define DEBUGLINMIN */
                    914: /* #define DEBUGHESS */
                    915: #define DEBUGHESSIJ
1.224     brouard   916: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   917: #define POWELL /* Instead of NLOPT */
1.224     brouard   918: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   919: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    920: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   921: 
                    922: #include <math.h>
                    923: #include <stdio.h>
                    924: #include <stdlib.h>
                    925: #include <string.h>
1.226     brouard   926: #include <ctype.h>
1.159     brouard   927: 
                    928: #ifdef _WIN32
                    929: #include <io.h>
1.172     brouard   930: #include <windows.h>
                    931: #include <tchar.h>
1.159     brouard   932: #else
1.126     brouard   933: #include <unistd.h>
1.159     brouard   934: #endif
1.126     brouard   935: 
                    936: #include <limits.h>
                    937: #include <sys/types.h>
1.171     brouard   938: 
                    939: #if defined(__GNUC__)
                    940: #include <sys/utsname.h> /* Doesn't work on Windows */
                    941: #endif
                    942: 
1.126     brouard   943: #include <sys/stat.h>
                    944: #include <errno.h>
1.159     brouard   945: /* extern int errno; */
1.126     brouard   946: 
1.157     brouard   947: /* #ifdef LINUX */
                    948: /* #include <time.h> */
                    949: /* #include "timeval.h" */
                    950: /* #else */
                    951: /* #include <sys/time.h> */
                    952: /* #endif */
                    953: 
1.126     brouard   954: #include <time.h>
                    955: 
1.136     brouard   956: #ifdef GSL
                    957: #include <gsl/gsl_errno.h>
                    958: #include <gsl/gsl_multimin.h>
                    959: #endif
                    960: 
1.167     brouard   961: 
1.162     brouard   962: #ifdef NLOPT
                    963: #include <nlopt.h>
                    964: typedef struct {
                    965:   double (* function)(double [] );
                    966: } myfunc_data ;
                    967: #endif
                    968: 
1.126     brouard   969: /* #include <libintl.h> */
                    970: /* #define _(String) gettext (String) */
                    971: 
1.251     brouard   972: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   973: 
                    974: #define GNUPLOTPROGRAM "gnuplot"
                    975: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    976: #define FILENAMELENGTH 132
                    977: 
                    978: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    979: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    980: 
1.144     brouard   981: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    982: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   983: 
                    984: #define NINTERVMAX 8
1.144     brouard   985: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    986: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    987: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard   988: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard   989: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                    990: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard   991: #define MAXN 20000
1.144     brouard   992: #define YEARM 12. /**< Number of months per year */
1.218     brouard   993: /* #define AGESUP 130 */
                    994: #define AGESUP 150
1.268     brouard   995: #define AGEINF 0
1.218     brouard   996: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard   997: #define AGEBASE 40
1.194     brouard   998: #define AGEOVERFLOW 1.e20
1.164     brouard   999: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1000: #ifdef _WIN32
                   1001: #define DIRSEPARATOR '\\'
                   1002: #define CHARSEPARATOR "\\"
                   1003: #define ODIRSEPARATOR '/'
                   1004: #else
1.126     brouard  1005: #define DIRSEPARATOR '/'
                   1006: #define CHARSEPARATOR "/"
                   1007: #define ODIRSEPARATOR '\\'
                   1008: #endif
                   1009: 
1.269   ! brouard  1010: /* $Id: imach.c,v 1.268 2017/05/18 20:09:32 brouard Exp $ */
1.126     brouard  1011: /* $State: Exp $ */
1.196     brouard  1012: #include "version.h"
                   1013: char version[]=__IMACH_VERSION__;
1.224     brouard  1014: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.269   ! brouard  1015: char fullversion[]="$Revision: 1.268 $ $Date: 2017/05/18 20:09:32 $"; 
1.126     brouard  1016: char strstart[80];
                   1017: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1018: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1019: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1020: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1021: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1022: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1023: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1024: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1025: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1026: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1027: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1028: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1029: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1030: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1031: int nsd=0; /**< Total number of single dummy variables (output) */
                   1032: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1033: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1034: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1035: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1036: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1037: int cptcov=0; /* Working variable */
1.218     brouard  1038: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1039: int npar=NPARMAX;
                   1040: int nlstate=2; /* Number of live states */
                   1041: int ndeath=1; /* Number of dead states */
1.130     brouard  1042: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1043: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1044: int popbased=0;
                   1045: 
                   1046: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1047: int maxwav=0; /* Maxim number of waves */
                   1048: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1049: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1050: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1051:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1052: int mle=1, weightopt=0;
1.126     brouard  1053: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1054: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1055: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1056:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1057: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1058: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1059: 
1.130     brouard  1060: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1061: double **matprod2(); /* test */
1.126     brouard  1062: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1063: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1064: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1065: 
1.136     brouard  1066: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1067: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1068: FILE *ficlog, *ficrespow;
1.130     brouard  1069: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1070: double fretone; /* Only one call to likelihood */
1.130     brouard  1071: long ipmx=0; /* Number of contributions */
1.126     brouard  1072: double sw; /* Sum of weights */
                   1073: char filerespow[FILENAMELENGTH];
                   1074: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1075: FILE *ficresilk;
                   1076: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1077: FILE *ficresprobmorprev;
                   1078: FILE *fichtm, *fichtmcov; /* Html File */
                   1079: FILE *ficreseij;
                   1080: char filerese[FILENAMELENGTH];
                   1081: FILE *ficresstdeij;
                   1082: char fileresstde[FILENAMELENGTH];
                   1083: FILE *ficrescveij;
                   1084: char filerescve[FILENAMELENGTH];
                   1085: FILE  *ficresvij;
                   1086: char fileresv[FILENAMELENGTH];
1.269   ! brouard  1087: 
1.126     brouard  1088: char title[MAXLINE];
1.234     brouard  1089: char model[MAXLINE]; /**< The model line */
1.217     brouard  1090: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1091: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1092: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1093: char command[FILENAMELENGTH];
                   1094: int  outcmd=0;
                   1095: 
1.217     brouard  1096: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1097: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1098: char filelog[FILENAMELENGTH]; /* Log file */
                   1099: char filerest[FILENAMELENGTH];
                   1100: char fileregp[FILENAMELENGTH];
                   1101: char popfile[FILENAMELENGTH];
                   1102: 
                   1103: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1104: 
1.157     brouard  1105: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1106: /* struct timezone tzp; */
                   1107: /* extern int gettimeofday(); */
                   1108: struct tm tml, *gmtime(), *localtime();
                   1109: 
                   1110: extern time_t time();
                   1111: 
                   1112: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1113: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1114: struct tm tm;
                   1115: 
1.126     brouard  1116: char strcurr[80], strfor[80];
                   1117: 
                   1118: char *endptr;
                   1119: long lval;
                   1120: double dval;
                   1121: 
                   1122: #define NR_END 1
                   1123: #define FREE_ARG char*
                   1124: #define FTOL 1.0e-10
                   1125: 
                   1126: #define NRANSI 
1.240     brouard  1127: #define ITMAX 200
                   1128: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1129: 
                   1130: #define TOL 2.0e-4 
                   1131: 
                   1132: #define CGOLD 0.3819660 
                   1133: #define ZEPS 1.0e-10 
                   1134: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1135: 
                   1136: #define GOLD 1.618034 
                   1137: #define GLIMIT 100.0 
                   1138: #define TINY 1.0e-20 
                   1139: 
                   1140: static double maxarg1,maxarg2;
                   1141: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1142: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1143:   
                   1144: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1145: #define rint(a) floor(a+0.5)
1.166     brouard  1146: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1147: #define mytinydouble 1.0e-16
1.166     brouard  1148: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1149: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1150: /* static double dsqrarg; */
                   1151: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1152: static double sqrarg;
                   1153: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1154: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1155: int agegomp= AGEGOMP;
                   1156: 
                   1157: int imx; 
                   1158: int stepm=1;
                   1159: /* Stepm, step in month: minimum step interpolation*/
                   1160: 
                   1161: int estepm;
                   1162: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1163: 
                   1164: int m,nb;
                   1165: long *num;
1.197     brouard  1166: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1167: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1168:                   covariate for which somebody answered excluding 
                   1169:                   undefined. Usually 2: 0 and 1. */
                   1170: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1171:                             covariate for which somebody answered including 
                   1172:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1173: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1174: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1175: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1176: double *ageexmed,*agecens;
                   1177: double dateintmean=0;
                   1178: 
                   1179: double *weight;
                   1180: int **s; /* Status */
1.141     brouard  1181: double *agedc;
1.145     brouard  1182: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1183:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1184:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1185: double **coqvar; /* Fixed quantitative covariate nqv */
                   1186: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1187: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1188: double  idx; 
                   1189: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1190: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1191: /*k          1  2   3   4     5    6    7     8    9 */
                   1192: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1193: /* Tndvar[k]    1   2   3               4          5 */
                   1194: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1195: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1196: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1197: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1198: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1199: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1200: /* Tprod[i]=k           4               7            */
                   1201: /* Tage[i]=k                  5               8      */
                   1202: /* */
                   1203: /* Type                    */
                   1204: /* V         1  2  3  4  5 */
                   1205: /*           F  F  V  V  V */
                   1206: /*           D  Q  D  D  Q */
                   1207: /*                         */
                   1208: int *TvarsD;
                   1209: int *TvarsDind;
                   1210: int *TvarsQ;
                   1211: int *TvarsQind;
                   1212: 
1.235     brouard  1213: #define MAXRESULTLINES 10
                   1214: int nresult=0;
1.258     brouard  1215: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1216: int TKresult[MAXRESULTLINES];
1.237     brouard  1217: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1218: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1219: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1220: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1221: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1222: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1223: 
1.234     brouard  1224: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1225: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1226: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1227: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1228: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1229: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1230: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1231: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1232: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1233: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1234: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1235: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1236: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1237: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1238: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1239: 
1.230     brouard  1240: int *Tvarsel; /**< Selected covariates for output */
                   1241: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1242: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1243: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1244: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1245: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1246: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1247: int *Tage;
1.227     brouard  1248: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1249: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1250: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1251: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1252: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1253: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1254: int **Tvard;
                   1255: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1256: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1257: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1258:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1259:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1260: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1261: double *lsurv, *lpop, *tpop;
                   1262: 
1.231     brouard  1263: #define FD 1; /* Fixed dummy covariate */
                   1264: #define FQ 2; /* Fixed quantitative covariate */
                   1265: #define FP 3; /* Fixed product covariate */
                   1266: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1267: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1268: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1269: #define VD 10; /* Varying dummy covariate */
                   1270: #define VQ 11; /* Varying quantitative covariate */
                   1271: #define VP 12; /* Varying product covariate */
                   1272: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1273: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1274: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1275: #define APFD 16; /* Age product * fixed dummy covariate */
                   1276: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1277: #define APVD 18; /* Age product * varying dummy covariate */
                   1278: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1279: 
                   1280: #define FTYPE 1; /* Fixed covariate */
                   1281: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1282: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1283: 
                   1284: struct kmodel{
                   1285:        int maintype; /* main type */
                   1286:        int subtype; /* subtype */
                   1287: };
                   1288: struct kmodel modell[NCOVMAX];
                   1289: 
1.143     brouard  1290: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1291: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1292: 
                   1293: /**************** split *************************/
                   1294: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1295: {
                   1296:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1297:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1298:   */ 
                   1299:   char *ss;                            /* pointer */
1.186     brouard  1300:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1301: 
                   1302:   l1 = strlen(path );                  /* length of path */
                   1303:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1304:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1305:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1306:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1307:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1308:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1309:     /* get current working directory */
                   1310:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1311: #ifdef WIN32
                   1312:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1313: #else
                   1314:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1315: #endif
1.126     brouard  1316:       return( GLOCK_ERROR_GETCWD );
                   1317:     }
                   1318:     /* got dirc from getcwd*/
                   1319:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1320:   } else {                             /* strip directory from path */
1.126     brouard  1321:     ss++;                              /* after this, the filename */
                   1322:     l2 = strlen( ss );                 /* length of filename */
                   1323:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1324:     strcpy( name, ss );                /* save file name */
                   1325:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1326:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1327:     printf(" DIRC2 = %s \n",dirc);
                   1328:   }
                   1329:   /* We add a separator at the end of dirc if not exists */
                   1330:   l1 = strlen( dirc );                 /* length of directory */
                   1331:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1332:     dirc[l1] =  DIRSEPARATOR;
                   1333:     dirc[l1+1] = 0; 
                   1334:     printf(" DIRC3 = %s \n",dirc);
                   1335:   }
                   1336:   ss = strrchr( name, '.' );           /* find last / */
                   1337:   if (ss >0){
                   1338:     ss++;
                   1339:     strcpy(ext,ss);                    /* save extension */
                   1340:     l1= strlen( name);
                   1341:     l2= strlen(ss)+1;
                   1342:     strncpy( finame, name, l1-l2);
                   1343:     finame[l1-l2]= 0;
                   1344:   }
                   1345: 
                   1346:   return( 0 );                         /* we're done */
                   1347: }
                   1348: 
                   1349: 
                   1350: /******************************************/
                   1351: 
                   1352: void replace_back_to_slash(char *s, char*t)
                   1353: {
                   1354:   int i;
                   1355:   int lg=0;
                   1356:   i=0;
                   1357:   lg=strlen(t);
                   1358:   for(i=0; i<= lg; i++) {
                   1359:     (s[i] = t[i]);
                   1360:     if (t[i]== '\\') s[i]='/';
                   1361:   }
                   1362: }
                   1363: 
1.132     brouard  1364: char *trimbb(char *out, char *in)
1.137     brouard  1365: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1366:   char *s;
                   1367:   s=out;
                   1368:   while (*in != '\0'){
1.137     brouard  1369:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1370:       in++;
                   1371:     }
                   1372:     *out++ = *in++;
                   1373:   }
                   1374:   *out='\0';
                   1375:   return s;
                   1376: }
                   1377: 
1.187     brouard  1378: /* char *substrchaine(char *out, char *in, char *chain) */
                   1379: /* { */
                   1380: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1381: /*   char *s, *t; */
                   1382: /*   t=in;s=out; */
                   1383: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1384: /*     *out++ = *in++; */
                   1385: /*   } */
                   1386: 
                   1387: /*   /\* *in matches *chain *\/ */
                   1388: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1389: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1390: /*   } */
                   1391: /*   in--; chain--; */
                   1392: /*   while ( (*in != '\0')){ */
                   1393: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1394: /*     *out++ = *in++; */
                   1395: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1396: /*   } */
                   1397: /*   *out='\0'; */
                   1398: /*   out=s; */
                   1399: /*   return out; */
                   1400: /* } */
                   1401: char *substrchaine(char *out, char *in, char *chain)
                   1402: {
                   1403:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1404:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1405: 
                   1406:   char *strloc;
                   1407: 
                   1408:   strcpy (out, in); 
                   1409:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1410:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1411:   if(strloc != NULL){ 
                   1412:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1413:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1414:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1415:   }
                   1416:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1417:   return out;
                   1418: }
                   1419: 
                   1420: 
1.145     brouard  1421: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1422: {
1.187     brouard  1423:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1424:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1425:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1426:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1427:   */
1.160     brouard  1428:   char *s, *t;
1.145     brouard  1429:   t=in;s=in;
                   1430:   while ((*in != occ) && (*in != '\0')){
                   1431:     *alocc++ = *in++;
                   1432:   }
                   1433:   if( *in == occ){
                   1434:     *(alocc)='\0';
                   1435:     s=++in;
                   1436:   }
                   1437:  
                   1438:   if (s == t) {/* occ not found */
                   1439:     *(alocc-(in-s))='\0';
                   1440:     in=s;
                   1441:   }
                   1442:   while ( *in != '\0'){
                   1443:     *blocc++ = *in++;
                   1444:   }
                   1445: 
                   1446:   *blocc='\0';
                   1447:   return t;
                   1448: }
1.137     brouard  1449: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1450: {
1.187     brouard  1451:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1452:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1453:      gives blocc="abcdef2ghi" and alocc="j".
                   1454:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1455:   */
                   1456:   char *s, *t;
                   1457:   t=in;s=in;
                   1458:   while (*in != '\0'){
                   1459:     while( *in == occ){
                   1460:       *blocc++ = *in++;
                   1461:       s=in;
                   1462:     }
                   1463:     *blocc++ = *in++;
                   1464:   }
                   1465:   if (s == t) /* occ not found */
                   1466:     *(blocc-(in-s))='\0';
                   1467:   else
                   1468:     *(blocc-(in-s)-1)='\0';
                   1469:   in=s;
                   1470:   while ( *in != '\0'){
                   1471:     *alocc++ = *in++;
                   1472:   }
                   1473: 
                   1474:   *alocc='\0';
                   1475:   return s;
                   1476: }
                   1477: 
1.126     brouard  1478: int nbocc(char *s, char occ)
                   1479: {
                   1480:   int i,j=0;
                   1481:   int lg=20;
                   1482:   i=0;
                   1483:   lg=strlen(s);
                   1484:   for(i=0; i<= lg; i++) {
1.234     brouard  1485:     if  (s[i] == occ ) j++;
1.126     brouard  1486:   }
                   1487:   return j;
                   1488: }
                   1489: 
1.137     brouard  1490: /* void cutv(char *u,char *v, char*t, char occ) */
                   1491: /* { */
                   1492: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1493: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1494: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1495: /*   int i,lg,j,p=0; */
                   1496: /*   i=0; */
                   1497: /*   lg=strlen(t); */
                   1498: /*   for(j=0; j<=lg-1; j++) { */
                   1499: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1500: /*   } */
1.126     brouard  1501: 
1.137     brouard  1502: /*   for(j=0; j<p; j++) { */
                   1503: /*     (u[j] = t[j]); */
                   1504: /*   } */
                   1505: /*      u[p]='\0'; */
1.126     brouard  1506: 
1.137     brouard  1507: /*    for(j=0; j<= lg; j++) { */
                   1508: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1509: /*   } */
                   1510: /* } */
1.126     brouard  1511: 
1.160     brouard  1512: #ifdef _WIN32
                   1513: char * strsep(char **pp, const char *delim)
                   1514: {
                   1515:   char *p, *q;
                   1516:          
                   1517:   if ((p = *pp) == NULL)
                   1518:     return 0;
                   1519:   if ((q = strpbrk (p, delim)) != NULL)
                   1520:   {
                   1521:     *pp = q + 1;
                   1522:     *q = '\0';
                   1523:   }
                   1524:   else
                   1525:     *pp = 0;
                   1526:   return p;
                   1527: }
                   1528: #endif
                   1529: 
1.126     brouard  1530: /********************** nrerror ********************/
                   1531: 
                   1532: void nrerror(char error_text[])
                   1533: {
                   1534:   fprintf(stderr,"ERREUR ...\n");
                   1535:   fprintf(stderr,"%s\n",error_text);
                   1536:   exit(EXIT_FAILURE);
                   1537: }
                   1538: /*********************** vector *******************/
                   1539: double *vector(int nl, int nh)
                   1540: {
                   1541:   double *v;
                   1542:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1543:   if (!v) nrerror("allocation failure in vector");
                   1544:   return v-nl+NR_END;
                   1545: }
                   1546: 
                   1547: /************************ free vector ******************/
                   1548: void free_vector(double*v, int nl, int nh)
                   1549: {
                   1550:   free((FREE_ARG)(v+nl-NR_END));
                   1551: }
                   1552: 
                   1553: /************************ivector *******************************/
                   1554: int *ivector(long nl,long nh)
                   1555: {
                   1556:   int *v;
                   1557:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1558:   if (!v) nrerror("allocation failure in ivector");
                   1559:   return v-nl+NR_END;
                   1560: }
                   1561: 
                   1562: /******************free ivector **************************/
                   1563: void free_ivector(int *v, long nl, long nh)
                   1564: {
                   1565:   free((FREE_ARG)(v+nl-NR_END));
                   1566: }
                   1567: 
                   1568: /************************lvector *******************************/
                   1569: long *lvector(long nl,long nh)
                   1570: {
                   1571:   long *v;
                   1572:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1573:   if (!v) nrerror("allocation failure in ivector");
                   1574:   return v-nl+NR_END;
                   1575: }
                   1576: 
                   1577: /******************free lvector **************************/
                   1578: void free_lvector(long *v, long nl, long nh)
                   1579: {
                   1580:   free((FREE_ARG)(v+nl-NR_END));
                   1581: }
                   1582: 
                   1583: /******************* imatrix *******************************/
                   1584: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1585:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1586: { 
                   1587:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1588:   int **m; 
                   1589:   
                   1590:   /* allocate pointers to rows */ 
                   1591:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1592:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1593:   m += NR_END; 
                   1594:   m -= nrl; 
                   1595:   
                   1596:   
                   1597:   /* allocate rows and set pointers to them */ 
                   1598:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1599:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1600:   m[nrl] += NR_END; 
                   1601:   m[nrl] -= ncl; 
                   1602:   
                   1603:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1604:   
                   1605:   /* return pointer to array of pointers to rows */ 
                   1606:   return m; 
                   1607: } 
                   1608: 
                   1609: /****************** free_imatrix *************************/
                   1610: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1611:       int **m;
                   1612:       long nch,ncl,nrh,nrl; 
                   1613:      /* free an int matrix allocated by imatrix() */ 
                   1614: { 
                   1615:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1616:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1617: } 
                   1618: 
                   1619: /******************* matrix *******************************/
                   1620: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1621: {
                   1622:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1623:   double **m;
                   1624: 
                   1625:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1626:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1627:   m += NR_END;
                   1628:   m -= nrl;
                   1629: 
                   1630:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1631:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1632:   m[nrl] += NR_END;
                   1633:   m[nrl] -= ncl;
                   1634: 
                   1635:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1636:   return m;
1.145     brouard  1637:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1638: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1639: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1640:    */
                   1641: }
                   1642: 
                   1643: /*************************free matrix ************************/
                   1644: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1645: {
                   1646:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1647:   free((FREE_ARG)(m+nrl-NR_END));
                   1648: }
                   1649: 
                   1650: /******************* ma3x *******************************/
                   1651: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1652: {
                   1653:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1654:   double ***m;
                   1655: 
                   1656:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1657:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1658:   m += NR_END;
                   1659:   m -= nrl;
                   1660: 
                   1661:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1662:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1663:   m[nrl] += NR_END;
                   1664:   m[nrl] -= ncl;
                   1665: 
                   1666:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1667: 
                   1668:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1669:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1670:   m[nrl][ncl] += NR_END;
                   1671:   m[nrl][ncl] -= nll;
                   1672:   for (j=ncl+1; j<=nch; j++) 
                   1673:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1674:   
                   1675:   for (i=nrl+1; i<=nrh; i++) {
                   1676:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1677:     for (j=ncl+1; j<=nch; j++) 
                   1678:       m[i][j]=m[i][j-1]+nlay;
                   1679:   }
                   1680:   return m; 
                   1681:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1682:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1683:   */
                   1684: }
                   1685: 
                   1686: /*************************free ma3x ************************/
                   1687: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1688: {
                   1689:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1690:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1691:   free((FREE_ARG)(m+nrl-NR_END));
                   1692: }
                   1693: 
                   1694: /*************** function subdirf ***********/
                   1695: char *subdirf(char fileres[])
                   1696: {
                   1697:   /* Caution optionfilefiname is hidden */
                   1698:   strcpy(tmpout,optionfilefiname);
                   1699:   strcat(tmpout,"/"); /* Add to the right */
                   1700:   strcat(tmpout,fileres);
                   1701:   return tmpout;
                   1702: }
                   1703: 
                   1704: /*************** function subdirf2 ***********/
                   1705: char *subdirf2(char fileres[], char *preop)
                   1706: {
                   1707:   
                   1708:   /* Caution optionfilefiname is hidden */
                   1709:   strcpy(tmpout,optionfilefiname);
                   1710:   strcat(tmpout,"/");
                   1711:   strcat(tmpout,preop);
                   1712:   strcat(tmpout,fileres);
                   1713:   return tmpout;
                   1714: }
                   1715: 
                   1716: /*************** function subdirf3 ***********/
                   1717: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1718: {
                   1719:   
                   1720:   /* Caution optionfilefiname is hidden */
                   1721:   strcpy(tmpout,optionfilefiname);
                   1722:   strcat(tmpout,"/");
                   1723:   strcat(tmpout,preop);
                   1724:   strcat(tmpout,preop2);
                   1725:   strcat(tmpout,fileres);
                   1726:   return tmpout;
                   1727: }
1.213     brouard  1728:  
                   1729: /*************** function subdirfext ***********/
                   1730: char *subdirfext(char fileres[], char *preop, char *postop)
                   1731: {
                   1732:   
                   1733:   strcpy(tmpout,preop);
                   1734:   strcat(tmpout,fileres);
                   1735:   strcat(tmpout,postop);
                   1736:   return tmpout;
                   1737: }
1.126     brouard  1738: 
1.213     brouard  1739: /*************** function subdirfext3 ***********/
                   1740: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1741: {
                   1742:   
                   1743:   /* Caution optionfilefiname is hidden */
                   1744:   strcpy(tmpout,optionfilefiname);
                   1745:   strcat(tmpout,"/");
                   1746:   strcat(tmpout,preop);
                   1747:   strcat(tmpout,fileres);
                   1748:   strcat(tmpout,postop);
                   1749:   return tmpout;
                   1750: }
                   1751:  
1.162     brouard  1752: char *asc_diff_time(long time_sec, char ascdiff[])
                   1753: {
                   1754:   long sec_left, days, hours, minutes;
                   1755:   days = (time_sec) / (60*60*24);
                   1756:   sec_left = (time_sec) % (60*60*24);
                   1757:   hours = (sec_left) / (60*60) ;
                   1758:   sec_left = (sec_left) %(60*60);
                   1759:   minutes = (sec_left) /60;
                   1760:   sec_left = (sec_left) % (60);
                   1761:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1762:   return ascdiff;
                   1763: }
                   1764: 
1.126     brouard  1765: /***************** f1dim *************************/
                   1766: extern int ncom; 
                   1767: extern double *pcom,*xicom;
                   1768: extern double (*nrfunc)(double []); 
                   1769:  
                   1770: double f1dim(double x) 
                   1771: { 
                   1772:   int j; 
                   1773:   double f;
                   1774:   double *xt; 
                   1775:  
                   1776:   xt=vector(1,ncom); 
                   1777:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1778:   f=(*nrfunc)(xt); 
                   1779:   free_vector(xt,1,ncom); 
                   1780:   return f; 
                   1781: } 
                   1782: 
                   1783: /*****************brent *************************/
                   1784: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1785: {
                   1786:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1787:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1788:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1789:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1790:    * returned function value. 
                   1791:   */
1.126     brouard  1792:   int iter; 
                   1793:   double a,b,d,etemp;
1.159     brouard  1794:   double fu=0,fv,fw,fx;
1.164     brouard  1795:   double ftemp=0.;
1.126     brouard  1796:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1797:   double e=0.0; 
                   1798:  
                   1799:   a=(ax < cx ? ax : cx); 
                   1800:   b=(ax > cx ? ax : cx); 
                   1801:   x=w=v=bx; 
                   1802:   fw=fv=fx=(*f)(x); 
                   1803:   for (iter=1;iter<=ITMAX;iter++) { 
                   1804:     xm=0.5*(a+b); 
                   1805:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1806:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1807:     printf(".");fflush(stdout);
                   1808:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1809: #ifdef DEBUGBRENT
1.126     brouard  1810:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1811:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1812:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1813: #endif
                   1814:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1815:       *xmin=x; 
                   1816:       return fx; 
                   1817:     } 
                   1818:     ftemp=fu;
                   1819:     if (fabs(e) > tol1) { 
                   1820:       r=(x-w)*(fx-fv); 
                   1821:       q=(x-v)*(fx-fw); 
                   1822:       p=(x-v)*q-(x-w)*r; 
                   1823:       q=2.0*(q-r); 
                   1824:       if (q > 0.0) p = -p; 
                   1825:       q=fabs(q); 
                   1826:       etemp=e; 
                   1827:       e=d; 
                   1828:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1829:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1830:       else { 
1.224     brouard  1831:                                d=p/q; 
                   1832:                                u=x+d; 
                   1833:                                if (u-a < tol2 || b-u < tol2) 
                   1834:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1835:       } 
                   1836:     } else { 
                   1837:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1838:     } 
                   1839:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1840:     fu=(*f)(u); 
                   1841:     if (fu <= fx) { 
                   1842:       if (u >= x) a=x; else b=x; 
                   1843:       SHFT(v,w,x,u) 
1.183     brouard  1844:       SHFT(fv,fw,fx,fu) 
                   1845:     } else { 
                   1846:       if (u < x) a=u; else b=u; 
                   1847:       if (fu <= fw || w == x) { 
1.224     brouard  1848:                                v=w; 
                   1849:                                w=u; 
                   1850:                                fv=fw; 
                   1851:                                fw=fu; 
1.183     brouard  1852:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1853:                                v=u; 
                   1854:                                fv=fu; 
1.183     brouard  1855:       } 
                   1856:     } 
1.126     brouard  1857:   } 
                   1858:   nrerror("Too many iterations in brent"); 
                   1859:   *xmin=x; 
                   1860:   return fx; 
                   1861: } 
                   1862: 
                   1863: /****************** mnbrak ***********************/
                   1864: 
                   1865: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1866:            double (*func)(double)) 
1.183     brouard  1867: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1868: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1869: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1870: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1871:    */
1.126     brouard  1872:   double ulim,u,r,q, dum;
                   1873:   double fu; 
1.187     brouard  1874: 
                   1875:   double scale=10.;
                   1876:   int iterscale=0;
                   1877: 
                   1878:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1879:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1880: 
                   1881: 
                   1882:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1883:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1884:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1885:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1886:   /* } */
                   1887: 
1.126     brouard  1888:   if (*fb > *fa) { 
                   1889:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1890:     SHFT(dum,*fb,*fa,dum) 
                   1891:   } 
1.126     brouard  1892:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1893:   *fc=(*func)(*cx); 
1.183     brouard  1894: #ifdef DEBUG
1.224     brouard  1895:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1896:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1897: #endif
1.224     brouard  1898:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1899:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1900:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1901:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1902:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1903:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1904:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1905:       fu=(*func)(u); 
1.163     brouard  1906: #ifdef DEBUG
                   1907:       /* f(x)=A(x-u)**2+f(u) */
                   1908:       double A, fparabu; 
                   1909:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1910:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1911:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1912:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1913:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1914:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1915:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1916:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1917: #endif 
1.184     brouard  1918: #ifdef MNBRAKORIGINAL
1.183     brouard  1919: #else
1.191     brouard  1920: /*       if (fu > *fc) { */
                   1921: /* #ifdef DEBUG */
                   1922: /*       printf("mnbrak4  fu > fc \n"); */
                   1923: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1924: /* #endif */
                   1925: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1926: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1927: /*     dum=u; /\* Shifting c and u *\/ */
                   1928: /*     u = *cx; */
                   1929: /*     *cx = dum; */
                   1930: /*     dum = fu; */
                   1931: /*     fu = *fc; */
                   1932: /*     *fc =dum; */
                   1933: /*       } else { /\* end *\/ */
                   1934: /* #ifdef DEBUG */
                   1935: /*       printf("mnbrak3  fu < fc \n"); */
                   1936: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1937: /* #endif */
                   1938: /*     dum=u; /\* Shifting c and u *\/ */
                   1939: /*     u = *cx; */
                   1940: /*     *cx = dum; */
                   1941: /*     dum = fu; */
                   1942: /*     fu = *fc; */
                   1943: /*     *fc =dum; */
                   1944: /*       } */
1.224     brouard  1945: #ifdef DEBUGMNBRAK
                   1946:                 double A, fparabu; 
                   1947:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1948:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1949:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1950:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1951: #endif
1.191     brouard  1952:       dum=u; /* Shifting c and u */
                   1953:       u = *cx;
                   1954:       *cx = dum;
                   1955:       dum = fu;
                   1956:       fu = *fc;
                   1957:       *fc =dum;
1.183     brouard  1958: #endif
1.162     brouard  1959:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1960: #ifdef DEBUG
1.224     brouard  1961:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1962:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1963: #endif
1.126     brouard  1964:       fu=(*func)(u); 
                   1965:       if (fu < *fc) { 
1.183     brouard  1966: #ifdef DEBUG
1.224     brouard  1967:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1968:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1969: #endif
                   1970:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1971:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1972: #ifdef DEBUG
                   1973:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1974: #endif
                   1975:       } 
1.162     brouard  1976:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1977: #ifdef DEBUG
1.224     brouard  1978:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1979:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1980: #endif
1.126     brouard  1981:       u=ulim; 
                   1982:       fu=(*func)(u); 
1.183     brouard  1983:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1984: #ifdef DEBUG
1.224     brouard  1985:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1986:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1987: #endif
1.126     brouard  1988:       u=(*cx)+GOLD*(*cx-*bx); 
                   1989:       fu=(*func)(u); 
1.224     brouard  1990: #ifdef DEBUG
                   1991:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1992:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   1993: #endif
1.183     brouard  1994:     } /* end tests */
1.126     brouard  1995:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  1996:     SHFT(*fa,*fb,*fc,fu) 
                   1997: #ifdef DEBUG
1.224     brouard  1998:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   1999:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2000: #endif
                   2001:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2002: } 
                   2003: 
                   2004: /*************** linmin ************************/
1.162     brouard  2005: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2006: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2007: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2008: the value of func at the returned location p . This is actually all accomplished by calling the
                   2009: routines mnbrak and brent .*/
1.126     brouard  2010: int ncom; 
                   2011: double *pcom,*xicom;
                   2012: double (*nrfunc)(double []); 
                   2013:  
1.224     brouard  2014: #ifdef LINMINORIGINAL
1.126     brouard  2015: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2016: #else
                   2017: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2018: #endif
1.126     brouard  2019: { 
                   2020:   double brent(double ax, double bx, double cx, 
                   2021:               double (*f)(double), double tol, double *xmin); 
                   2022:   double f1dim(double x); 
                   2023:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2024:              double *fc, double (*func)(double)); 
                   2025:   int j; 
                   2026:   double xx,xmin,bx,ax; 
                   2027:   double fx,fb,fa;
1.187     brouard  2028: 
1.203     brouard  2029: #ifdef LINMINORIGINAL
                   2030: #else
                   2031:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2032: #endif
                   2033:   
1.126     brouard  2034:   ncom=n; 
                   2035:   pcom=vector(1,n); 
                   2036:   xicom=vector(1,n); 
                   2037:   nrfunc=func; 
                   2038:   for (j=1;j<=n;j++) { 
                   2039:     pcom[j]=p[j]; 
1.202     brouard  2040:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2041:   } 
1.187     brouard  2042: 
1.203     brouard  2043: #ifdef LINMINORIGINAL
                   2044:   xx=1.;
                   2045: #else
                   2046:   axs=0.0;
                   2047:   xxs=1.;
                   2048:   do{
                   2049:     xx= xxs;
                   2050: #endif
1.187     brouard  2051:     ax=0.;
                   2052:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2053:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2054:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2055:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2056:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2057:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2058:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2059: #ifdef LINMINORIGINAL
                   2060: #else
                   2061:     if (fx != fx){
1.224     brouard  2062:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2063:                        printf("|");
                   2064:                        fprintf(ficlog,"|");
1.203     brouard  2065: #ifdef DEBUGLINMIN
1.224     brouard  2066:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2067: #endif
                   2068:     }
1.224     brouard  2069:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2070: #endif
                   2071:   
1.191     brouard  2072: #ifdef DEBUGLINMIN
                   2073:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2074:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2075: #endif
1.224     brouard  2076: #ifdef LINMINORIGINAL
                   2077: #else
                   2078:        if(fb == fx){ /* Flat function in the direction */
                   2079:                xmin=xx;
                   2080:     *flat=1;
                   2081:        }else{
                   2082:     *flat=0;
                   2083: #endif
                   2084:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2085:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2086:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2087:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2088:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2089:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2090: #ifdef DEBUG
1.224     brouard  2091:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2092:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2093: #endif
                   2094: #ifdef LINMINORIGINAL
                   2095: #else
                   2096:                        }
1.126     brouard  2097: #endif
1.191     brouard  2098: #ifdef DEBUGLINMIN
                   2099:   printf("linmin end ");
1.202     brouard  2100:   fprintf(ficlog,"linmin end ");
1.191     brouard  2101: #endif
1.126     brouard  2102:   for (j=1;j<=n;j++) { 
1.203     brouard  2103: #ifdef LINMINORIGINAL
                   2104:     xi[j] *= xmin; 
                   2105: #else
                   2106: #ifdef DEBUGLINMIN
                   2107:     if(xxs <1.0)
                   2108:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2109: #endif
                   2110:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2111: #ifdef DEBUGLINMIN
                   2112:     if(xxs <1.0)
                   2113:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2114: #endif
                   2115: #endif
1.187     brouard  2116:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2117:   } 
1.191     brouard  2118: #ifdef DEBUGLINMIN
1.203     brouard  2119:   printf("\n");
1.191     brouard  2120:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2121:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2122:   for (j=1;j<=n;j++) { 
1.202     brouard  2123:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2124:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2125:     if(j % ncovmodel == 0){
1.191     brouard  2126:       printf("\n");
1.202     brouard  2127:       fprintf(ficlog,"\n");
                   2128:     }
1.191     brouard  2129:   }
1.203     brouard  2130: #else
1.191     brouard  2131: #endif
1.126     brouard  2132:   free_vector(xicom,1,n); 
                   2133:   free_vector(pcom,1,n); 
                   2134: } 
                   2135: 
                   2136: 
                   2137: /*************** powell ************************/
1.162     brouard  2138: /*
                   2139: Minimization of a function func of n variables. Input consists of an initial starting point
                   2140: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2141: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2142: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2143: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2144: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2145:  */
1.224     brouard  2146: #ifdef LINMINORIGINAL
                   2147: #else
                   2148:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2149:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2150: #endif
1.126     brouard  2151: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2152:            double (*func)(double [])) 
                   2153: { 
1.224     brouard  2154: #ifdef LINMINORIGINAL
                   2155:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2156:              double (*func)(double [])); 
1.224     brouard  2157: #else 
1.241     brouard  2158:  void linmin(double p[], double xi[], int n, double *fret,
                   2159:             double (*func)(double []),int *flat); 
1.224     brouard  2160: #endif
1.239     brouard  2161:  int i,ibig,j,jk,k; 
1.126     brouard  2162:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2163:   double directest;
1.126     brouard  2164:   double fp,fptt;
                   2165:   double *xits;
                   2166:   int niterf, itmp;
1.224     brouard  2167: #ifdef LINMINORIGINAL
                   2168: #else
                   2169: 
                   2170:   flatdir=ivector(1,n); 
                   2171:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2172: #endif
1.126     brouard  2173: 
                   2174:   pt=vector(1,n); 
                   2175:   ptt=vector(1,n); 
                   2176:   xit=vector(1,n); 
                   2177:   xits=vector(1,n); 
                   2178:   *fret=(*func)(p); 
                   2179:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2180:   rcurr_time = time(NULL);  
1.126     brouard  2181:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2182:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2183:     ibig=0; 
                   2184:     del=0.0; 
1.157     brouard  2185:     rlast_time=rcurr_time;
                   2186:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2187:     rcurr_time = time(NULL);  
                   2188:     curr_time = *localtime(&rcurr_time);
                   2189:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2190:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2191: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2192:     for (i=1;i<=n;i++) {
1.126     brouard  2193:       fprintf(ficrespow," %.12lf", p[i]);
                   2194:     }
1.239     brouard  2195:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2196:     printf("\n#model=  1      +     age ");
                   2197:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2198:     if(nagesqr==1){
1.241     brouard  2199:        printf("  + age*age  ");
                   2200:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2201:     }
                   2202:     for(j=1;j <=ncovmodel-2;j++){
                   2203:       if(Typevar[j]==0) {
                   2204:        printf("  +      V%d  ",Tvar[j]);
                   2205:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2206:       }else if(Typevar[j]==1) {
                   2207:        printf("  +    V%d*age ",Tvar[j]);
                   2208:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2209:       }else if(Typevar[j]==2) {
                   2210:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2211:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2212:       }
                   2213:     }
1.126     brouard  2214:     printf("\n");
1.239     brouard  2215: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2216: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2217:     fprintf(ficlog,"\n");
1.239     brouard  2218:     for(i=1,jk=1; i <=nlstate; i++){
                   2219:       for(k=1; k <=(nlstate+ndeath); k++){
                   2220:        if (k != i) {
                   2221:          printf("%d%d ",i,k);
                   2222:          fprintf(ficlog,"%d%d ",i,k);
                   2223:          for(j=1; j <=ncovmodel; j++){
                   2224:            printf("%12.7f ",p[jk]);
                   2225:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2226:            jk++; 
                   2227:          }
                   2228:          printf("\n");
                   2229:          fprintf(ficlog,"\n");
                   2230:        }
                   2231:       }
                   2232:     }
1.241     brouard  2233:     if(*iter <=3 && *iter >1){
1.157     brouard  2234:       tml = *localtime(&rcurr_time);
                   2235:       strcpy(strcurr,asctime(&tml));
                   2236:       rforecast_time=rcurr_time; 
1.126     brouard  2237:       itmp = strlen(strcurr);
                   2238:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2239:        strcurr[itmp-1]='\0';
1.162     brouard  2240:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2241:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2242:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2243:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2244:        forecast_time = *localtime(&rforecast_time);
                   2245:        strcpy(strfor,asctime(&forecast_time));
                   2246:        itmp = strlen(strfor);
                   2247:        if(strfor[itmp-1]=='\n')
                   2248:          strfor[itmp-1]='\0';
                   2249:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2250:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2251:       }
                   2252:     }
1.187     brouard  2253:     for (i=1;i<=n;i++) { /* For each direction i */
                   2254:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2255:       fptt=(*fret); 
                   2256: #ifdef DEBUG
1.203     brouard  2257:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2258:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2259: #endif
1.203     brouard  2260:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2261:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2262: #ifdef LINMINORIGINAL
1.188     brouard  2263:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2264: #else
                   2265:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2266:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2267: #endif
                   2268:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2269:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2270:                                /* because that direction will be replaced unless the gain del is small */
                   2271:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2272:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2273:                                /* with the new direction. */
                   2274:                                del=fabs(fptt-(*fret)); 
                   2275:                                ibig=i; 
1.126     brouard  2276:       } 
                   2277: #ifdef DEBUG
                   2278:       printf("%d %.12e",i,(*fret));
                   2279:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2280:       for (j=1;j<=n;j++) {
1.224     brouard  2281:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2282:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2283:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2284:       }
                   2285:       for(j=1;j<=n;j++) {
1.225     brouard  2286:                                printf(" p(%d)=%.12e",j,p[j]);
                   2287:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2288:       }
                   2289:       printf("\n");
                   2290:       fprintf(ficlog,"\n");
                   2291: #endif
1.187     brouard  2292:     } /* end loop on each direction i */
                   2293:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2294:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2295:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2296:       for(j=1;j<=n;j++) {
1.225     brouard  2297:                                if(flatdir[j] >0){
                   2298:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2299:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2300:                                }
                   2301:                                /* printf("\n"); */
                   2302:                                /* fprintf(ficlog,"\n"); */
                   2303:                        }
1.243     brouard  2304:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2305:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2306:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2307:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2308:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2309:       /* decreased of more than 3.84  */
                   2310:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2311:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2312:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2313:                        
1.188     brouard  2314:       /* Starting the program with initial values given by a former maximization will simply change */
                   2315:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2316:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2317:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2318: #ifdef DEBUG
                   2319:       int k[2],l;
                   2320:       k[0]=1;
                   2321:       k[1]=-1;
                   2322:       printf("Max: %.12e",(*func)(p));
                   2323:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2324:       for (j=1;j<=n;j++) {
                   2325:        printf(" %.12e",p[j]);
                   2326:        fprintf(ficlog," %.12e",p[j]);
                   2327:       }
                   2328:       printf("\n");
                   2329:       fprintf(ficlog,"\n");
                   2330:       for(l=0;l<=1;l++) {
                   2331:        for (j=1;j<=n;j++) {
                   2332:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2333:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2334:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2335:        }
                   2336:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2337:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2338:       }
                   2339: #endif
                   2340: 
1.224     brouard  2341: #ifdef LINMINORIGINAL
                   2342: #else
                   2343:       free_ivector(flatdir,1,n); 
                   2344: #endif
1.126     brouard  2345:       free_vector(xit,1,n); 
                   2346:       free_vector(xits,1,n); 
                   2347:       free_vector(ptt,1,n); 
                   2348:       free_vector(pt,1,n); 
                   2349:       return; 
1.192     brouard  2350:     } /* enough precision */ 
1.240     brouard  2351:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2352:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2353:       ptt[j]=2.0*p[j]-pt[j]; 
                   2354:       xit[j]=p[j]-pt[j]; 
                   2355:       pt[j]=p[j]; 
                   2356:     } 
1.181     brouard  2357:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2358: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2359:                if (*iter <=4) {
1.225     brouard  2360: #else
                   2361: #endif
1.224     brouard  2362: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2363: #else
1.161     brouard  2364:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2365: #endif
1.162     brouard  2366:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2367:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2368:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2369:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2370:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2371:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2372:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2373:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2374:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2375:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2376:       /* mu² and del² are equal when f3=f1 */
                   2377:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2378:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2379:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2380:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2381: #ifdef NRCORIGINAL
                   2382:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2383: #else
                   2384:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2385:       t= t- del*SQR(fp-fptt);
1.183     brouard  2386: #endif
1.202     brouard  2387:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2388: #ifdef DEBUG
1.181     brouard  2389:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2390:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2391:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2392:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2393:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2394:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2395:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2396:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2397: #endif
1.183     brouard  2398: #ifdef POWELLORIGINAL
                   2399:       if (t < 0.0) { /* Then we use it for new direction */
                   2400: #else
1.182     brouard  2401:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2402:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2403:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2404:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2405:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2406:       } 
1.181     brouard  2407:       if (directest < 0.0) { /* Then we use it for new direction */
                   2408: #endif
1.191     brouard  2409: #ifdef DEBUGLINMIN
1.234     brouard  2410:        printf("Before linmin in direction P%d-P0\n",n);
                   2411:        for (j=1;j<=n;j++) {
                   2412:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2413:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2414:          if(j % ncovmodel == 0){
                   2415:            printf("\n");
                   2416:            fprintf(ficlog,"\n");
                   2417:          }
                   2418:        }
1.224     brouard  2419: #endif
                   2420: #ifdef LINMINORIGINAL
1.234     brouard  2421:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2422: #else
1.234     brouard  2423:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2424:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2425: #endif
1.234     brouard  2426:        
1.191     brouard  2427: #ifdef DEBUGLINMIN
1.234     brouard  2428:        for (j=1;j<=n;j++) { 
                   2429:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2430:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2431:          if(j % ncovmodel == 0){
                   2432:            printf("\n");
                   2433:            fprintf(ficlog,"\n");
                   2434:          }
                   2435:        }
1.224     brouard  2436: #endif
1.234     brouard  2437:        for (j=1;j<=n;j++) { 
                   2438:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2439:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2440:        }
1.224     brouard  2441: #ifdef LINMINORIGINAL
                   2442: #else
1.234     brouard  2443:        for (j=1, flatd=0;j<=n;j++) {
                   2444:          if(flatdir[j]>0)
                   2445:            flatd++;
                   2446:        }
                   2447:        if(flatd >0){
1.255     brouard  2448:          printf("%d flat directions: ",flatd);
                   2449:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2450:          for (j=1;j<=n;j++) { 
                   2451:            if(flatdir[j]>0){
                   2452:              printf("%d ",j);
                   2453:              fprintf(ficlog,"%d ",j);
                   2454:            }
                   2455:          }
                   2456:          printf("\n");
                   2457:          fprintf(ficlog,"\n");
                   2458:        }
1.191     brouard  2459: #endif
1.234     brouard  2460:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2461:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2462:        
1.126     brouard  2463: #ifdef DEBUG
1.234     brouard  2464:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2465:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2466:        for(j=1;j<=n;j++){
                   2467:          printf(" %lf",xit[j]);
                   2468:          fprintf(ficlog," %lf",xit[j]);
                   2469:        }
                   2470:        printf("\n");
                   2471:        fprintf(ficlog,"\n");
1.126     brouard  2472: #endif
1.192     brouard  2473:       } /* end of t or directest negative */
1.224     brouard  2474: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2475: #else
1.234     brouard  2476:       } /* end if (fptt < fp)  */
1.192     brouard  2477: #endif
1.225     brouard  2478: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2479:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2480: #else
1.224     brouard  2481: #endif
1.234     brouard  2482:                } /* loop iteration */ 
1.126     brouard  2483: } 
1.234     brouard  2484:   
1.126     brouard  2485: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2486:   
1.235     brouard  2487:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2488:   {
1.235     brouard  2489:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2490:        (and selected quantitative values in nres)
                   2491:        by left multiplying the unit
1.234     brouard  2492:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2493:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2494:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2495:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2496:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2497:   /* Initial matrix pimij */
                   2498:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2499:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2500:   /*  0,                   0                  , 1} */
                   2501:   /*
                   2502:    * and after some iteration: */
                   2503:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2504:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2505:   /*  0,                   0                  , 1} */
                   2506:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2507:   /* {0.51571254859325999, 0.4842874514067399, */
                   2508:   /*  0.51326036147820708, 0.48673963852179264} */
                   2509:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2510:     
1.126     brouard  2511:   int i, ii,j,k;
1.209     brouard  2512:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2513:   /* double **matprod2(); */ /* test */
1.218     brouard  2514:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2515:   double **newm;
1.209     brouard  2516:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2517:   int ncvloop=0;
1.169     brouard  2518:   
1.209     brouard  2519:   min=vector(1,nlstate);
                   2520:   max=vector(1,nlstate);
                   2521:   meandiff=vector(1,nlstate);
                   2522: 
1.218     brouard  2523:        /* Starting with matrix unity */
1.126     brouard  2524:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2525:     for (j=1;j<=nlstate+ndeath;j++){
                   2526:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2527:     }
1.169     brouard  2528:   
                   2529:   cov[1]=1.;
                   2530:   
                   2531:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2532:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2533:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2534:     ncvloop++;
1.126     brouard  2535:     newm=savm;
                   2536:     /* Covariates have to be included here again */
1.138     brouard  2537:     cov[2]=agefin;
1.187     brouard  2538:     if(nagesqr==1)
                   2539:       cov[3]= agefin*agefin;;
1.234     brouard  2540:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2541:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2542:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2543:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2544:     }
                   2545:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2546:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2547:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2548:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2549:     }
1.237     brouard  2550:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2551:       if(Dummy[Tvar[Tage[k]]]){
                   2552:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2553:       } else{
1.235     brouard  2554:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2555:       }
1.235     brouard  2556:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2557:     }
1.237     brouard  2558:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2559:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2560:       if(Dummy[Tvard[k][1]==0]){
                   2561:        if(Dummy[Tvard[k][2]==0]){
                   2562:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2563:        }else{
                   2564:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2565:        }
                   2566:       }else{
                   2567:        if(Dummy[Tvard[k][2]==0]){
                   2568:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2569:        }else{
                   2570:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2571:        }
                   2572:       }
1.234     brouard  2573:     }
1.138     brouard  2574:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2575:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2576:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2577:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2578:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2579:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2580:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2581:     
1.126     brouard  2582:     savm=oldm;
                   2583:     oldm=newm;
1.209     brouard  2584: 
                   2585:     for(j=1; j<=nlstate; j++){
                   2586:       max[j]=0.;
                   2587:       min[j]=1.;
                   2588:     }
                   2589:     for(i=1;i<=nlstate;i++){
                   2590:       sumnew=0;
                   2591:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2592:       for(j=1; j<=nlstate; j++){ 
                   2593:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2594:        max[j]=FMAX(max[j],prlim[i][j]);
                   2595:        min[j]=FMIN(min[j],prlim[i][j]);
                   2596:       }
                   2597:     }
                   2598: 
1.126     brouard  2599:     maxmax=0.;
1.209     brouard  2600:     for(j=1; j<=nlstate; j++){
                   2601:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2602:       maxmax=FMAX(maxmax,meandiff[j]);
                   2603:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2604:     } /* j loop */
1.203     brouard  2605:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2606:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2607:     if(maxmax < ftolpl){
1.209     brouard  2608:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2609:       free_vector(min,1,nlstate);
                   2610:       free_vector(max,1,nlstate);
                   2611:       free_vector(meandiff,1,nlstate);
1.126     brouard  2612:       return prlim;
                   2613:     }
1.169     brouard  2614:   } /* age loop */
1.208     brouard  2615:     /* After some age loop it doesn't converge */
1.209     brouard  2616:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2617: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2618:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2619:   free_vector(min,1,nlstate);
                   2620:   free_vector(max,1,nlstate);
                   2621:   free_vector(meandiff,1,nlstate);
1.208     brouard  2622:   
1.169     brouard  2623:   return prlim; /* should not reach here */
1.126     brouard  2624: }
                   2625: 
1.217     brouard  2626: 
                   2627:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2628: 
1.218     brouard  2629:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2630:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2631:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2632: {
1.264     brouard  2633:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2634:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2635:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2636:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2637:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2638:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2639:   /* Initial matrix pimij */
                   2640:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2641:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2642:   /*  0,                   0                  , 1} */
                   2643:   /*
                   2644:    * and after some iteration: */
                   2645:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2646:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2647:   /*  0,                   0                  , 1} */
                   2648:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2649:   /* {0.51571254859325999, 0.4842874514067399, */
                   2650:   /*  0.51326036147820708, 0.48673963852179264} */
                   2651:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2652: 
                   2653:   int i, ii,j,k;
1.247     brouard  2654:   int first=0;
1.217     brouard  2655:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2656:   /* double **matprod2(); */ /* test */
                   2657:   double **out, cov[NCOVMAX+1], **bmij();
                   2658:   double **newm;
1.218     brouard  2659:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2660:   double        **oldm, **savm;  /* for use */
                   2661: 
1.217     brouard  2662:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2663:   int ncvloop=0;
                   2664:   
                   2665:   min=vector(1,nlstate);
                   2666:   max=vector(1,nlstate);
                   2667:   meandiff=vector(1,nlstate);
                   2668: 
1.266     brouard  2669:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2670:   oldm=oldms; savm=savms;
                   2671:   
                   2672:   /* Starting with matrix unity */
                   2673:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2674:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2675:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2676:     }
                   2677:   
                   2678:   cov[1]=1.;
                   2679:   
                   2680:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2681:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2682:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2683:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2684:     ncvloop++;
1.218     brouard  2685:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2686:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2687:     /* Covariates have to be included here again */
                   2688:     cov[2]=agefin;
                   2689:     if(nagesqr==1)
                   2690:       cov[3]= agefin*agefin;;
1.242     brouard  2691:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2692:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2693:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2694:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2695:     }
                   2696:     /* for (k=1; k<=cptcovn;k++) { */
                   2697:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2698:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2699:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2700:     /* } */
                   2701:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2702:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2703:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2704:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2705:     }
                   2706:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2707:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2708:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2709:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2710:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2711:       if(Dummy[Tvar[Tage[k]]]){
                   2712:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2713:       } else{
                   2714:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2715:       }
                   2716:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2717:     }
                   2718:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2719:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2720:       if(Dummy[Tvard[k][1]==0]){
                   2721:        if(Dummy[Tvard[k][2]==0]){
                   2722:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2723:        }else{
                   2724:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2725:        }
                   2726:       }else{
                   2727:        if(Dummy[Tvard[k][2]==0]){
                   2728:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2729:        }else{
                   2730:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2731:        }
                   2732:       }
1.217     brouard  2733:     }
                   2734:     
                   2735:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2736:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2737:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2738:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2739:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2740:                /* ij should be linked to the correct index of cov */
                   2741:                /* age and covariate values ij are in 'cov', but we need to pass
                   2742:                 * ij for the observed prevalence at age and status and covariate
                   2743:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2744:                 */
                   2745:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2746:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2747:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2748:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2749:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2750:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2751:     /*         printf("%d newm= ",i); */
                   2752:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2753:     /*           printf("%f ",newm[i][j]); */
                   2754:     /*         } */
                   2755:     /*         printf("oldm * "); */
                   2756:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2757:     /*           printf("%f ",oldm[i][j]); */
                   2758:     /*         } */
1.268     brouard  2759:     /*         printf(" bmmij "); */
1.266     brouard  2760:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2761:     /*           printf("%f ",pmmij[i][j]); */
                   2762:     /*         } */
                   2763:     /*         printf("\n"); */
                   2764:     /*   } */
                   2765:     /* } */
1.217     brouard  2766:     savm=oldm;
                   2767:     oldm=newm;
1.266     brouard  2768: 
1.217     brouard  2769:     for(j=1; j<=nlstate; j++){
                   2770:       max[j]=0.;
                   2771:       min[j]=1.;
                   2772:     }
                   2773:     for(j=1; j<=nlstate; j++){ 
                   2774:       for(i=1;i<=nlstate;i++){
1.234     brouard  2775:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2776:        bprlim[i][j]= newm[i][j];
                   2777:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2778:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2779:       }
                   2780:     }
1.218     brouard  2781:                
1.217     brouard  2782:     maxmax=0.;
                   2783:     for(i=1; i<=nlstate; i++){
                   2784:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2785:       maxmax=FMAX(maxmax,meandiff[i]);
                   2786:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2787:     } /* i loop */
1.217     brouard  2788:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2789:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2790:     if(maxmax < ftolpl){
1.220     brouard  2791:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2792:       free_vector(min,1,nlstate);
                   2793:       free_vector(max,1,nlstate);
                   2794:       free_vector(meandiff,1,nlstate);
                   2795:       return bprlim;
                   2796:     }
                   2797:   } /* age loop */
                   2798:     /* After some age loop it doesn't converge */
1.247     brouard  2799:   if(first){
                   2800:     first=1;
                   2801:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2802: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2803:   }
                   2804:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2805: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2806:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2807:   free_vector(min,1,nlstate);
                   2808:   free_vector(max,1,nlstate);
                   2809:   free_vector(meandiff,1,nlstate);
                   2810:   
                   2811:   return bprlim; /* should not reach here */
                   2812: }
                   2813: 
1.126     brouard  2814: /*************** transition probabilities ***************/ 
                   2815: 
                   2816: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2817: {
1.138     brouard  2818:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2819:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2820:      model to the ncovmodel covariates (including constant and age).
                   2821:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2822:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2823:      ncth covariate in the global vector x is given by the formula:
                   2824:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2825:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2826:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2827:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2828:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2829:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2830:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2831:   */
                   2832:   double s1, lnpijopii;
1.126     brouard  2833:   /*double t34;*/
1.164     brouard  2834:   int i,j, nc, ii, jj;
1.126     brouard  2835: 
1.223     brouard  2836:   for(i=1; i<= nlstate; i++){
                   2837:     for(j=1; j<i;j++){
                   2838:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2839:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2840:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2841:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2842:       }
                   2843:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2844:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2845:     }
                   2846:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2847:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2848:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2849:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2850:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2851:       }
                   2852:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2853:     }
                   2854:   }
1.218     brouard  2855:   
1.223     brouard  2856:   for(i=1; i<= nlstate; i++){
                   2857:     s1=0;
                   2858:     for(j=1; j<i; j++){
                   2859:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2860:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2861:     }
                   2862:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2863:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2864:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2865:     }
                   2866:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2867:     ps[i][i]=1./(s1+1.);
                   2868:     /* Computing other pijs */
                   2869:     for(j=1; j<i; j++)
                   2870:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2871:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2872:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2873:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2874:   } /* end i */
1.218     brouard  2875:   
1.223     brouard  2876:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2877:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2878:       ps[ii][jj]=0;
                   2879:       ps[ii][ii]=1;
                   2880:     }
                   2881:   }
1.218     brouard  2882:   
                   2883:   
1.223     brouard  2884:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2885:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2886:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2887:   /*   } */
                   2888:   /*   printf("\n "); */
                   2889:   /* } */
                   2890:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2891:   /*
                   2892:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2893:                goto end;*/
1.266     brouard  2894:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2895: }
                   2896: 
1.218     brouard  2897: /*************** backward transition probabilities ***************/ 
                   2898: 
                   2899:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2900: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2901:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2902: {
1.266     brouard  2903:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2904:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2905:    */
1.218     brouard  2906:   int i, ii, j,k;
1.222     brouard  2907:   
                   2908:   double **out, **pmij();
                   2909:   double sumnew=0.;
1.218     brouard  2910:   double agefin;
1.268     brouard  2911:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2912:   double **dnewm, **dsavm, **doldm;
                   2913:   double **bbmij;
                   2914:   
1.218     brouard  2915:   doldm=ddoldms; /* global pointers */
1.222     brouard  2916:   dnewm=ddnewms;
                   2917:   dsavm=ddsavms;
                   2918:   
                   2919:   agefin=cov[2];
1.268     brouard  2920:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2921:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2922:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2923:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2924: 
                   2925:   /* P_x */
1.266     brouard  2926:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2927:   /* outputs pmmij which is a stochastic matrix in row */
                   2928: 
                   2929:   /* Diag(w_x) */
                   2930:   /* Problem with prevacurrent which can be zero */
                   2931:   sumnew=0.;
1.269   ! brouard  2932:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2933:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269   ! brouard  2934:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2935:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2936:   }
                   2937:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2938:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2939:       for (j=1;j<=nlstate+ndeath;j++)
1.269   ! brouard  2940:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2941:     }
                   2942:   }else{
                   2943:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2944:       for (j=1;j<=nlstate+ndeath;j++)
                   2945:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2946:     }
                   2947:     /* if(sumnew <0.9){ */
                   2948:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   2949:     /* } */
                   2950:   }
                   2951:   k3=0.0;  /* We put the last diagonal to 0 */
                   2952:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   2953:       doldm[ii][ii]= k3;
                   2954:   }
                   2955:   /* End doldm, At the end doldm is diag[(w_i)] */
                   2956:   
                   2957:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   2958:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   2959: 
                   2960:   /* Diag(Sum_i w^i_x p^ij_x */
                   2961:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  2962:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  2963:     sumnew=0.;
1.222     brouard  2964:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  2965:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  2966:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  2967:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  2968:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  2969:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  2970:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2971:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  2972:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2973:        /* }else */
1.268     brouard  2974:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2975:     } /*End ii */
                   2976:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   2977: 
                   2978:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   2979:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  2980:   /* end bmij */
1.266     brouard  2981:   return ps; /*pointer is unchanged */
1.218     brouard  2982: }
1.217     brouard  2983: /*************** transition probabilities ***************/ 
                   2984: 
1.218     brouard  2985: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2986: {
                   2987:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   2988:      computes the probability to be observed in state j being in state i by appying the
                   2989:      model to the ncovmodel covariates (including constant and age).
                   2990:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2991:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2992:      ncth covariate in the global vector x is given by the formula:
                   2993:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2994:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2995:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2996:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   2997:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   2998:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   2999:   */
                   3000:   double s1, lnpijopii;
                   3001:   /*double t34;*/
                   3002:   int i,j, nc, ii, jj;
                   3003: 
1.234     brouard  3004:   for(i=1; i<= nlstate; i++){
                   3005:     for(j=1; j<i;j++){
                   3006:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3007:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3008:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3009:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3010:       }
                   3011:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3012:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3013:     }
                   3014:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3015:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3016:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3017:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3018:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3019:       }
                   3020:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3021:     }
                   3022:   }
                   3023:   
                   3024:   for(i=1; i<= nlstate; i++){
                   3025:     s1=0;
                   3026:     for(j=1; j<i; j++){
                   3027:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3028:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3029:     }
                   3030:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3031:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3032:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3033:     }
                   3034:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3035:     ps[i][i]=1./(s1+1.);
                   3036:     /* Computing other pijs */
                   3037:     for(j=1; j<i; j++)
                   3038:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3039:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3040:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3041:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3042:   } /* end i */
                   3043:   
                   3044:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3045:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3046:       ps[ii][jj]=0;
                   3047:       ps[ii][ii]=1;
                   3048:     }
                   3049:   }
                   3050:   /* Added for backcast */ /* Transposed matrix too */
                   3051:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3052:     s1=0.;
                   3053:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3054:       s1+=ps[ii][jj];
                   3055:     }
                   3056:     for(ii=1; ii<= nlstate; ii++){
                   3057:       ps[ii][jj]=ps[ii][jj]/s1;
                   3058:     }
                   3059:   }
                   3060:   /* Transposition */
                   3061:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3062:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3063:       s1=ps[ii][jj];
                   3064:       ps[ii][jj]=ps[jj][ii];
                   3065:       ps[jj][ii]=s1;
                   3066:     }
                   3067:   }
                   3068:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3069:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3070:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3071:   /*   } */
                   3072:   /*   printf("\n "); */
                   3073:   /* } */
                   3074:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3075:   /*
                   3076:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3077:     goto end;*/
                   3078:   return ps;
1.217     brouard  3079: }
                   3080: 
                   3081: 
1.126     brouard  3082: /**************** Product of 2 matrices ******************/
                   3083: 
1.145     brouard  3084: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3085: {
                   3086:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3087:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3088:   /* in, b, out are matrice of pointers which should have been initialized 
                   3089:      before: only the contents of out is modified. The function returns
                   3090:      a pointer to pointers identical to out */
1.145     brouard  3091:   int i, j, k;
1.126     brouard  3092:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3093:     for(k=ncolol; k<=ncoloh; k++){
                   3094:       out[i][k]=0.;
                   3095:       for(j=ncl; j<=nch; j++)
                   3096:        out[i][k] +=in[i][j]*b[j][k];
                   3097:     }
1.126     brouard  3098:   return out;
                   3099: }
                   3100: 
                   3101: 
                   3102: /************* Higher Matrix Product ***************/
                   3103: 
1.235     brouard  3104: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3105: {
1.218     brouard  3106:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3107:      'nhstepm*hstepm*stepm' months (i.e. until
                   3108:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3109:      nhstepm*hstepm matrices. 
                   3110:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3111:      (typically every 2 years instead of every month which is too big 
                   3112:      for the memory).
                   3113:      Model is determined by parameters x and covariates have to be 
                   3114:      included manually here. 
                   3115: 
                   3116:      */
                   3117: 
                   3118:   int i, j, d, h, k;
1.131     brouard  3119:   double **out, cov[NCOVMAX+1];
1.126     brouard  3120:   double **newm;
1.187     brouard  3121:   double agexact;
1.214     brouard  3122:   double agebegin, ageend;
1.126     brouard  3123: 
                   3124:   /* Hstepm could be zero and should return the unit matrix */
                   3125:   for (i=1;i<=nlstate+ndeath;i++)
                   3126:     for (j=1;j<=nlstate+ndeath;j++){
                   3127:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3128:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3129:     }
                   3130:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3131:   for(h=1; h <=nhstepm; h++){
                   3132:     for(d=1; d <=hstepm; d++){
                   3133:       newm=savm;
                   3134:       /* Covariates have to be included here again */
                   3135:       cov[1]=1.;
1.214     brouard  3136:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3137:       cov[2]=agexact;
                   3138:       if(nagesqr==1)
1.227     brouard  3139:        cov[3]= agexact*agexact;
1.235     brouard  3140:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3141:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3142:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3143:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3144:       }
                   3145:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3146:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3147:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3148:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3149:       }
                   3150:       for (k=1; k<=cptcovage;k++){
                   3151:        if(Dummy[Tvar[Tage[k]]]){
                   3152:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3153:        } else{
                   3154:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3155:        }
                   3156:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3157:       }
                   3158:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3159:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3160:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3161:       }
                   3162:       /* for (k=1; k<=cptcovn;k++)  */
                   3163:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3164:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3165:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3166:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3167:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3168:       
                   3169:       
1.126     brouard  3170:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3171:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3172:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3173:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3174:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3175:       /* if((int)age == 70){ */
                   3176:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3177:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3178:       /*         printf("%d pmmij ",i); */
                   3179:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3180:       /*           printf("%f ",pmmij[i][j]); */
                   3181:       /*         } */
                   3182:       /*         printf(" oldm "); */
                   3183:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3184:       /*           printf("%f ",oldm[i][j]); */
                   3185:       /*         } */
                   3186:       /*         printf("\n"); */
                   3187:       /*       } */
                   3188:       /* } */
1.126     brouard  3189:       savm=oldm;
                   3190:       oldm=newm;
                   3191:     }
                   3192:     for(i=1; i<=nlstate+ndeath; i++)
                   3193:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3194:        po[i][j][h]=newm[i][j];
                   3195:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3196:       }
1.128     brouard  3197:     /*printf("h=%d ",h);*/
1.126     brouard  3198:   } /* end h */
1.267     brouard  3199:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3200:   return po;
                   3201: }
                   3202: 
1.217     brouard  3203: /************* Higher Back Matrix Product ***************/
1.218     brouard  3204: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3205: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3206: {
1.266     brouard  3207:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3208:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3209:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3210:      nhstepm*hstepm matrices.
                   3211:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3212:      (typically every 2 years instead of every month which is too big
1.217     brouard  3213:      for the memory).
1.218     brouard  3214:      Model is determined by parameters x and covariates have to be
1.266     brouard  3215:      included manually here. Then we use a call to bmij(x and cov)
                   3216:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3217:   */
1.217     brouard  3218: 
                   3219:   int i, j, d, h, k;
1.266     brouard  3220:   double **out, cov[NCOVMAX+1], **bmij();
                   3221:   double **newm, ***newmm;
1.217     brouard  3222:   double agexact;
                   3223:   double agebegin, ageend;
1.222     brouard  3224:   double **oldm, **savm;
1.217     brouard  3225: 
1.266     brouard  3226:   newmm=po; /* To be saved */
                   3227:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3228:   /* Hstepm could be zero and should return the unit matrix */
                   3229:   for (i=1;i<=nlstate+ndeath;i++)
                   3230:     for (j=1;j<=nlstate+ndeath;j++){
                   3231:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3232:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3233:     }
                   3234:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3235:   for(h=1; h <=nhstepm; h++){
                   3236:     for(d=1; d <=hstepm; d++){
                   3237:       newm=savm;
                   3238:       /* Covariates have to be included here again */
                   3239:       cov[1]=1.;
1.266     brouard  3240:       agexact=age-((h-1)*hstepm + (d))*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3241:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3242:       cov[2]=agexact;
                   3243:       if(nagesqr==1)
1.222     brouard  3244:        cov[3]= agexact*agexact;
1.266     brouard  3245:       for (k=1; k<=cptcovn;k++){
                   3246:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3247:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3248:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3249:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3250:       }
1.267     brouard  3251:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3252:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3253:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3254:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3255:       }
                   3256:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3257:        if(Dummy[Tvar[Tage[k]]]){
                   3258:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3259:        } else{
                   3260:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3261:        }
                   3262:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3263:       }
                   3264:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3265:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3266:       }                        
1.217     brouard  3267:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3268:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3269: 
1.218     brouard  3270:       /* Careful transposed matrix */
1.266     brouard  3271:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3272:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3273:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3274:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3275:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3276:       /* if((int)age == 70){ */
                   3277:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3278:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3279:       /*         printf("%d pmmij ",i); */
                   3280:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3281:       /*           printf("%f ",pmmij[i][j]); */
                   3282:       /*         } */
                   3283:       /*         printf(" oldm "); */
                   3284:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3285:       /*           printf("%f ",oldm[i][j]); */
                   3286:       /*         } */
                   3287:       /*         printf("\n"); */
                   3288:       /*       } */
                   3289:       /* } */
                   3290:       savm=oldm;
                   3291:       oldm=newm;
                   3292:     }
                   3293:     for(i=1; i<=nlstate+ndeath; i++)
                   3294:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3295:        po[i][j][h]=newm[i][j];
1.268     brouard  3296:        /* if(h==nhstepm) */
                   3297:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3298:       }
1.268     brouard  3299:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3300:   } /* end h */
1.268     brouard  3301:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3302:   return po;
                   3303: }
                   3304: 
                   3305: 
1.162     brouard  3306: #ifdef NLOPT
                   3307:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3308:   double fret;
                   3309:   double *xt;
                   3310:   int j;
                   3311:   myfunc_data *d2 = (myfunc_data *) pd;
                   3312: /* xt = (p1-1); */
                   3313:   xt=vector(1,n); 
                   3314:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3315: 
                   3316:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3317:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3318:   printf("Function = %.12lf ",fret);
                   3319:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3320:   printf("\n");
                   3321:  free_vector(xt,1,n);
                   3322:   return fret;
                   3323: }
                   3324: #endif
1.126     brouard  3325: 
                   3326: /*************** log-likelihood *************/
                   3327: double func( double *x)
                   3328: {
1.226     brouard  3329:   int i, ii, j, k, mi, d, kk;
                   3330:   int ioffset=0;
                   3331:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3332:   double **out;
                   3333:   double lli; /* Individual log likelihood */
                   3334:   int s1, s2;
1.228     brouard  3335:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3336:   double bbh, survp;
                   3337:   long ipmx;
                   3338:   double agexact;
                   3339:   /*extern weight */
                   3340:   /* We are differentiating ll according to initial status */
                   3341:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3342:   /*for(i=1;i<imx;i++) 
                   3343:     printf(" %d\n",s[4][i]);
                   3344:   */
1.162     brouard  3345: 
1.226     brouard  3346:   ++countcallfunc;
1.162     brouard  3347: 
1.226     brouard  3348:   cov[1]=1.;
1.126     brouard  3349: 
1.226     brouard  3350:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3351:   ioffset=0;
1.226     brouard  3352:   if(mle==1){
                   3353:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3354:       /* Computes the values of the ncovmodel covariates of the model
                   3355:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3356:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3357:         to be observed in j being in i according to the model.
                   3358:       */
1.243     brouard  3359:       ioffset=2+nagesqr ;
1.233     brouard  3360:    /* Fixed */
1.234     brouard  3361:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3362:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3363:       }
1.226     brouard  3364:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3365:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3366:         has been calculated etc */
                   3367:       /* For an individual i, wav[i] gives the number of effective waves */
                   3368:       /* We compute the contribution to Likelihood of each effective transition
                   3369:         mw[mi][i] is real wave of the mi th effectve wave */
                   3370:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3371:         s2=s[mw[mi+1][i]][i];
                   3372:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3373:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3374:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3375:       */
                   3376:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3377:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3378:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3379:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3380:        }
                   3381:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3382:          for (j=1;j<=nlstate+ndeath;j++){
                   3383:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3384:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3385:          }
                   3386:        for(d=0; d<dh[mi][i]; d++){
                   3387:          newm=savm;
                   3388:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3389:          cov[2]=agexact;
                   3390:          if(nagesqr==1)
                   3391:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3392:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3393:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3394:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3395:          else
                   3396:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3397:          }
                   3398:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3399:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3400:          savm=oldm;
                   3401:          oldm=newm;
                   3402:        } /* end mult */
                   3403:        
                   3404:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3405:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3406:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3407:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3408:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3409:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3410:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3411:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3412:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3413:                                 * -stepm/2 to stepm/2 .
                   3414:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3415:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3416:                                 */
1.234     brouard  3417:        s1=s[mw[mi][i]][i];
                   3418:        s2=s[mw[mi+1][i]][i];
                   3419:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3420:        /* bias bh is positive if real duration
                   3421:         * is higher than the multiple of stepm and negative otherwise.
                   3422:         */
                   3423:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3424:        if( s2 > nlstate){ 
                   3425:          /* i.e. if s2 is a death state and if the date of death is known 
                   3426:             then the contribution to the likelihood is the probability to 
                   3427:             die between last step unit time and current  step unit time, 
                   3428:             which is also equal to probability to die before dh 
                   3429:             minus probability to die before dh-stepm . 
                   3430:             In version up to 0.92 likelihood was computed
                   3431:             as if date of death was unknown. Death was treated as any other
                   3432:             health state: the date of the interview describes the actual state
                   3433:             and not the date of a change in health state. The former idea was
                   3434:             to consider that at each interview the state was recorded
                   3435:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3436:             introduced the exact date of death then we should have modified
                   3437:             the contribution of an exact death to the likelihood. This new
                   3438:             contribution is smaller and very dependent of the step unit
                   3439:             stepm. It is no more the probability to die between last interview
                   3440:             and month of death but the probability to survive from last
                   3441:             interview up to one month before death multiplied by the
                   3442:             probability to die within a month. Thanks to Chris
                   3443:             Jackson for correcting this bug.  Former versions increased
                   3444:             mortality artificially. The bad side is that we add another loop
                   3445:             which slows down the processing. The difference can be up to 10%
                   3446:             lower mortality.
                   3447:          */
                   3448:          /* If, at the beginning of the maximization mostly, the
                   3449:             cumulative probability or probability to be dead is
                   3450:             constant (ie = 1) over time d, the difference is equal to
                   3451:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3452:             s1 at precedent wave, to be dead a month before current
                   3453:             wave is equal to probability, being at state s1 at
                   3454:             precedent wave, to be dead at mont of the current
                   3455:             wave. Then the observed probability (that this person died)
                   3456:             is null according to current estimated parameter. In fact,
                   3457:             it should be very low but not zero otherwise the log go to
                   3458:             infinity.
                   3459:          */
1.183     brouard  3460: /* #ifdef INFINITYORIGINAL */
                   3461: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3462: /* #else */
                   3463: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3464: /*         lli=log(mytinydouble); */
                   3465: /*       else */
                   3466: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3467: /* #endif */
1.226     brouard  3468:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3469:          
1.226     brouard  3470:        } else if  ( s2==-1 ) { /* alive */
                   3471:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3472:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3473:          /*survp += out[s1][j]; */
                   3474:          lli= log(survp);
                   3475:        }
                   3476:        else if  (s2==-4) { 
                   3477:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3478:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3479:          lli= log(survp); 
                   3480:        } 
                   3481:        else if  (s2==-5) { 
                   3482:          for (j=1,survp=0. ; j<=2; j++)  
                   3483:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3484:          lli= log(survp); 
                   3485:        } 
                   3486:        else{
                   3487:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3488:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3489:        } 
                   3490:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3491:        /*if(lli ==000.0)*/
                   3492:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3493:        ipmx +=1;
                   3494:        sw += weight[i];
                   3495:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3496:        /* if (lli < log(mytinydouble)){ */
                   3497:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3498:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3499:        /* } */
                   3500:       } /* end of wave */
                   3501:     } /* end of individual */
                   3502:   }  else if(mle==2){
                   3503:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3504:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3505:       for(mi=1; mi<= wav[i]-1; mi++){
                   3506:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3507:          for (j=1;j<=nlstate+ndeath;j++){
                   3508:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3509:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3510:          }
                   3511:        for(d=0; d<=dh[mi][i]; d++){
                   3512:          newm=savm;
                   3513:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3514:          cov[2]=agexact;
                   3515:          if(nagesqr==1)
                   3516:            cov[3]= agexact*agexact;
                   3517:          for (kk=1; kk<=cptcovage;kk++) {
                   3518:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3519:          }
                   3520:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3521:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3522:          savm=oldm;
                   3523:          oldm=newm;
                   3524:        } /* end mult */
                   3525:       
                   3526:        s1=s[mw[mi][i]][i];
                   3527:        s2=s[mw[mi+1][i]][i];
                   3528:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3529:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3530:        ipmx +=1;
                   3531:        sw += weight[i];
                   3532:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3533:       } /* end of wave */
                   3534:     } /* end of individual */
                   3535:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3536:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3537:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3538:       for(mi=1; mi<= wav[i]-1; mi++){
                   3539:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3540:          for (j=1;j<=nlstate+ndeath;j++){
                   3541:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3542:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3543:          }
                   3544:        for(d=0; d<dh[mi][i]; d++){
                   3545:          newm=savm;
                   3546:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3547:          cov[2]=agexact;
                   3548:          if(nagesqr==1)
                   3549:            cov[3]= agexact*agexact;
                   3550:          for (kk=1; kk<=cptcovage;kk++) {
                   3551:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3552:          }
                   3553:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3554:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3555:          savm=oldm;
                   3556:          oldm=newm;
                   3557:        } /* end mult */
                   3558:       
                   3559:        s1=s[mw[mi][i]][i];
                   3560:        s2=s[mw[mi+1][i]][i];
                   3561:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3562:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3563:        ipmx +=1;
                   3564:        sw += weight[i];
                   3565:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3566:       } /* end of wave */
                   3567:     } /* end of individual */
                   3568:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3569:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3570:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3571:       for(mi=1; mi<= wav[i]-1; mi++){
                   3572:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3573:          for (j=1;j<=nlstate+ndeath;j++){
                   3574:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3575:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3576:          }
                   3577:        for(d=0; d<dh[mi][i]; d++){
                   3578:          newm=savm;
                   3579:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3580:          cov[2]=agexact;
                   3581:          if(nagesqr==1)
                   3582:            cov[3]= agexact*agexact;
                   3583:          for (kk=1; kk<=cptcovage;kk++) {
                   3584:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3585:          }
1.126     brouard  3586:        
1.226     brouard  3587:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3588:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3589:          savm=oldm;
                   3590:          oldm=newm;
                   3591:        } /* end mult */
                   3592:       
                   3593:        s1=s[mw[mi][i]][i];
                   3594:        s2=s[mw[mi+1][i]][i];
                   3595:        if( s2 > nlstate){ 
                   3596:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3597:        } else if  ( s2==-1 ) { /* alive */
                   3598:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3599:            survp += out[s1][j];
                   3600:          lli= log(survp);
                   3601:        }else{
                   3602:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3603:        }
                   3604:        ipmx +=1;
                   3605:        sw += weight[i];
                   3606:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3607: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3608:       } /* end of wave */
                   3609:     } /* end of individual */
                   3610:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3611:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3612:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3613:       for(mi=1; mi<= wav[i]-1; mi++){
                   3614:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3615:          for (j=1;j<=nlstate+ndeath;j++){
                   3616:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3617:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3618:          }
                   3619:        for(d=0; d<dh[mi][i]; d++){
                   3620:          newm=savm;
                   3621:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3622:          cov[2]=agexact;
                   3623:          if(nagesqr==1)
                   3624:            cov[3]= agexact*agexact;
                   3625:          for (kk=1; kk<=cptcovage;kk++) {
                   3626:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3627:          }
1.126     brouard  3628:        
1.226     brouard  3629:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3630:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3631:          savm=oldm;
                   3632:          oldm=newm;
                   3633:        } /* end mult */
                   3634:       
                   3635:        s1=s[mw[mi][i]][i];
                   3636:        s2=s[mw[mi+1][i]][i];
                   3637:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3638:        ipmx +=1;
                   3639:        sw += weight[i];
                   3640:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3641:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3642:       } /* end of wave */
                   3643:     } /* end of individual */
                   3644:   } /* End of if */
                   3645:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3646:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3647:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3648:   return -l;
1.126     brouard  3649: }
                   3650: 
                   3651: /*************** log-likelihood *************/
                   3652: double funcone( double *x)
                   3653: {
1.228     brouard  3654:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3655:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3656:   int ioffset=0;
1.131     brouard  3657:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3658:   double **out;
                   3659:   double lli; /* Individual log likelihood */
                   3660:   double llt;
                   3661:   int s1, s2;
1.228     brouard  3662:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3663: 
1.126     brouard  3664:   double bbh, survp;
1.187     brouard  3665:   double agexact;
1.214     brouard  3666:   double agebegin, ageend;
1.126     brouard  3667:   /*extern weight */
                   3668:   /* We are differentiating ll according to initial status */
                   3669:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3670:   /*for(i=1;i<imx;i++) 
                   3671:     printf(" %d\n",s[4][i]);
                   3672:   */
                   3673:   cov[1]=1.;
                   3674: 
                   3675:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3676:   ioffset=0;
                   3677:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3678:     /* ioffset=2+nagesqr+cptcovage; */
                   3679:     ioffset=2+nagesqr;
1.232     brouard  3680:     /* Fixed */
1.224     brouard  3681:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3682:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3683:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3684:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3685: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3686: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3687: /*    cov[2+6]=covar[2][i]; V2  */
                   3688: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3689: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3690: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3691: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3692: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3693: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3694:     }
1.232     brouard  3695:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3696:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3697:     /* } */
1.231     brouard  3698:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3699:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3700:     /* } */
1.225     brouard  3701:     
1.233     brouard  3702: 
                   3703:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3704:     /* Wave varying (but not age varying) */
                   3705:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3706:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3707:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3708:       }
1.232     brouard  3709:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3710:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3711:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3712:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3713:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3714:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3715:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3716:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3717:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3718:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3719:       /* } */
1.126     brouard  3720:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3721:        for (j=1;j<=nlstate+ndeath;j++){
                   3722:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3723:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3724:        }
1.214     brouard  3725:       
                   3726:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3727:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3728:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3729:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3730:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3731:          and mw[mi+1][i]. dh depends on stepm.*/
                   3732:        newm=savm;
1.247     brouard  3733:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3734:        cov[2]=agexact;
                   3735:        if(nagesqr==1)
                   3736:          cov[3]= agexact*agexact;
                   3737:        for (kk=1; kk<=cptcovage;kk++) {
                   3738:          if(!FixedV[Tvar[Tage[kk]]])
                   3739:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3740:          else
                   3741:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3742:        }
                   3743:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3744:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3745:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3746:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3747:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3748:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3749:        savm=oldm;
                   3750:        oldm=newm;
1.126     brouard  3751:       } /* end mult */
                   3752:       
                   3753:       s1=s[mw[mi][i]][i];
                   3754:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3755:       /* if(s2==-1){ */
1.268     brouard  3756:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3757:       /*       /\* exit(1); *\/ */
                   3758:       /* } */
1.126     brouard  3759:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3760:       /* bias is positive if real duration
                   3761:        * is higher than the multiple of stepm and negative otherwise.
                   3762:        */
                   3763:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3764:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3765:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3766:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3767:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3768:        lli= log(survp);
1.126     brouard  3769:       }else if (mle==1){
1.242     brouard  3770:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3771:       } else if(mle==2){
1.242     brouard  3772:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3773:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3774:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3775:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3776:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3777:       } else{  /* mle=0 back to 1 */
1.242     brouard  3778:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3779:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3780:       } /* End of if */
                   3781:       ipmx +=1;
                   3782:       sw += weight[i];
                   3783:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3784:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3785:       if(globpr){
1.246     brouard  3786:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3787:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3788:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3789:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3790:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3791:          llt +=ll[k]*gipmx/gsw;
                   3792:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3793:        }
                   3794:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3795:       }
1.232     brouard  3796:        } /* end of wave */
                   3797: } /* end of individual */
                   3798: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3799: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3800: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3801: if(globpr==0){ /* First time we count the contributions and weights */
                   3802:        gipmx=ipmx;
                   3803:        gsw=sw;
                   3804: }
                   3805: return -l;
1.126     brouard  3806: }
                   3807: 
                   3808: 
                   3809: /*************** function likelione ***********/
                   3810: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3811: {
                   3812:   /* This routine should help understanding what is done with 
                   3813:      the selection of individuals/waves and
                   3814:      to check the exact contribution to the likelihood.
                   3815:      Plotting could be done.
                   3816:    */
                   3817:   int k;
                   3818: 
                   3819:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3820:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3821:     strcat(fileresilk,fileresu);
1.126     brouard  3822:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3823:       printf("Problem with resultfile: %s\n", fileresilk);
                   3824:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3825:     }
1.214     brouard  3826:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3827:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3828:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3829:     for(k=1; k<=nlstate; k++) 
                   3830:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3831:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3832:   }
                   3833: 
                   3834:   *fretone=(*funcone)(p);
                   3835:   if(*globpri !=0){
                   3836:     fclose(ficresilk);
1.205     brouard  3837:     if (mle ==0)
                   3838:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3839:     else if(mle >=1)
                   3840:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3841:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3842:     
1.208     brouard  3843:       
                   3844:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3845:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3846: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3847:     }
1.207     brouard  3848:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3849: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3850:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3851: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3852:     fflush(fichtm);
1.205     brouard  3853:   }
1.126     brouard  3854:   return;
                   3855: }
                   3856: 
                   3857: 
                   3858: /*********** Maximum Likelihood Estimation ***************/
                   3859: 
                   3860: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3861: {
1.165     brouard  3862:   int i,j, iter=0;
1.126     brouard  3863:   double **xi;
                   3864:   double fret;
                   3865:   double fretone; /* Only one call to likelihood */
                   3866:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3867: 
                   3868: #ifdef NLOPT
                   3869:   int creturn;
                   3870:   nlopt_opt opt;
                   3871:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3872:   double *lb;
                   3873:   double minf; /* the minimum objective value, upon return */
                   3874:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3875:   myfunc_data dinst, *d = &dinst;
                   3876: #endif
                   3877: 
                   3878: 
1.126     brouard  3879:   xi=matrix(1,npar,1,npar);
                   3880:   for (i=1;i<=npar;i++)
                   3881:     for (j=1;j<=npar;j++)
                   3882:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3883:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3884:   strcpy(filerespow,"POW_"); 
1.126     brouard  3885:   strcat(filerespow,fileres);
                   3886:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3887:     printf("Problem with resultfile: %s\n", filerespow);
                   3888:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3889:   }
                   3890:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3891:   for (i=1;i<=nlstate;i++)
                   3892:     for(j=1;j<=nlstate+ndeath;j++)
                   3893:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3894:   fprintf(ficrespow,"\n");
1.162     brouard  3895: #ifdef POWELL
1.126     brouard  3896:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3897: #endif
1.126     brouard  3898: 
1.162     brouard  3899: #ifdef NLOPT
                   3900: #ifdef NEWUOA
                   3901:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3902: #else
                   3903:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3904: #endif
                   3905:   lb=vector(0,npar-1);
                   3906:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3907:   nlopt_set_lower_bounds(opt, lb);
                   3908:   nlopt_set_initial_step1(opt, 0.1);
                   3909:   
                   3910:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3911:   d->function = func;
                   3912:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3913:   nlopt_set_min_objective(opt, myfunc, d);
                   3914:   nlopt_set_xtol_rel(opt, ftol);
                   3915:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3916:     printf("nlopt failed! %d\n",creturn); 
                   3917:   }
                   3918:   else {
                   3919:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3920:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3921:     iter=1; /* not equal */
                   3922:   }
                   3923:   nlopt_destroy(opt);
                   3924: #endif
1.126     brouard  3925:   free_matrix(xi,1,npar,1,npar);
                   3926:   fclose(ficrespow);
1.203     brouard  3927:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3928:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3929:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3930: 
                   3931: }
                   3932: 
                   3933: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3934: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3935: {
                   3936:   double  **a,**y,*x,pd;
1.203     brouard  3937:   /* double **hess; */
1.164     brouard  3938:   int i, j;
1.126     brouard  3939:   int *indx;
                   3940: 
                   3941:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3942:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3943:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3944:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3945:   double gompertz(double p[]);
1.203     brouard  3946:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3947: 
                   3948:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3949:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3950:   for (i=1;i<=npar;i++){
1.203     brouard  3951:     printf("%d-",i);fflush(stdout);
                   3952:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3953:    
                   3954:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3955:     
                   3956:     /*  printf(" %f ",p[i]);
                   3957:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3958:   }
                   3959:   
                   3960:   for (i=1;i<=npar;i++) {
                   3961:     for (j=1;j<=npar;j++)  {
                   3962:       if (j>i) { 
1.203     brouard  3963:        printf(".%d-%d",i,j);fflush(stdout);
                   3964:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3965:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3966:        
                   3967:        hess[j][i]=hess[i][j];    
                   3968:        /*printf(" %lf ",hess[i][j]);*/
                   3969:       }
                   3970:     }
                   3971:   }
                   3972:   printf("\n");
                   3973:   fprintf(ficlog,"\n");
                   3974: 
                   3975:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3976:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3977:   
                   3978:   a=matrix(1,npar,1,npar);
                   3979:   y=matrix(1,npar,1,npar);
                   3980:   x=vector(1,npar);
                   3981:   indx=ivector(1,npar);
                   3982:   for (i=1;i<=npar;i++)
                   3983:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3984:   ludcmp(a,npar,indx,&pd);
                   3985: 
                   3986:   for (j=1;j<=npar;j++) {
                   3987:     for (i=1;i<=npar;i++) x[i]=0;
                   3988:     x[j]=1;
                   3989:     lubksb(a,npar,indx,x);
                   3990:     for (i=1;i<=npar;i++){ 
                   3991:       matcov[i][j]=x[i];
                   3992:     }
                   3993:   }
                   3994: 
                   3995:   printf("\n#Hessian matrix#\n");
                   3996:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   3997:   for (i=1;i<=npar;i++) { 
                   3998:     for (j=1;j<=npar;j++) { 
1.203     brouard  3999:       printf("%.6e ",hess[i][j]);
                   4000:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4001:     }
                   4002:     printf("\n");
                   4003:     fprintf(ficlog,"\n");
                   4004:   }
                   4005: 
1.203     brouard  4006:   /* printf("\n#Covariance matrix#\n"); */
                   4007:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4008:   /* for (i=1;i<=npar;i++) {  */
                   4009:   /*   for (j=1;j<=npar;j++) {  */
                   4010:   /*     printf("%.6e ",matcov[i][j]); */
                   4011:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4012:   /*   } */
                   4013:   /*   printf("\n"); */
                   4014:   /*   fprintf(ficlog,"\n"); */
                   4015:   /* } */
                   4016: 
1.126     brouard  4017:   /* Recompute Inverse */
1.203     brouard  4018:   /* for (i=1;i<=npar;i++) */
                   4019:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4020:   /* ludcmp(a,npar,indx,&pd); */
                   4021: 
                   4022:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4023: 
                   4024:   /* for (j=1;j<=npar;j++) { */
                   4025:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4026:   /*   x[j]=1; */
                   4027:   /*   lubksb(a,npar,indx,x); */
                   4028:   /*   for (i=1;i<=npar;i++){  */
                   4029:   /*     y[i][j]=x[i]; */
                   4030:   /*     printf("%.3e ",y[i][j]); */
                   4031:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4032:   /*   } */
                   4033:   /*   printf("\n"); */
                   4034:   /*   fprintf(ficlog,"\n"); */
                   4035:   /* } */
                   4036: 
                   4037:   /* Verifying the inverse matrix */
                   4038: #ifdef DEBUGHESS
                   4039:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4040: 
1.203     brouard  4041:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4042:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4043: 
                   4044:   for (j=1;j<=npar;j++) {
                   4045:     for (i=1;i<=npar;i++){ 
1.203     brouard  4046:       printf("%.2f ",y[i][j]);
                   4047:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4048:     }
                   4049:     printf("\n");
                   4050:     fprintf(ficlog,"\n");
                   4051:   }
1.203     brouard  4052: #endif
1.126     brouard  4053: 
                   4054:   free_matrix(a,1,npar,1,npar);
                   4055:   free_matrix(y,1,npar,1,npar);
                   4056:   free_vector(x,1,npar);
                   4057:   free_ivector(indx,1,npar);
1.203     brouard  4058:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4059: 
                   4060: 
                   4061: }
                   4062: 
                   4063: /*************** hessian matrix ****************/
                   4064: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4065: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4066:   int i;
                   4067:   int l=1, lmax=20;
1.203     brouard  4068:   double k1,k2, res, fx;
1.132     brouard  4069:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4070:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4071:   int k=0,kmax=10;
                   4072:   double l1;
                   4073: 
                   4074:   fx=func(x);
                   4075:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4076:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4077:     l1=pow(10,l);
                   4078:     delts=delt;
                   4079:     for(k=1 ; k <kmax; k=k+1){
                   4080:       delt = delta*(l1*k);
                   4081:       p2[theta]=x[theta] +delt;
1.145     brouard  4082:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4083:       p2[theta]=x[theta]-delt;
                   4084:       k2=func(p2)-fx;
                   4085:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4086:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4087:       
1.203     brouard  4088: #ifdef DEBUGHESSII
1.126     brouard  4089:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4090:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4091: #endif
                   4092:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4093:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4094:        k=kmax;
                   4095:       }
                   4096:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4097:        k=kmax; l=lmax*10;
1.126     brouard  4098:       }
                   4099:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4100:        delts=delt;
                   4101:       }
1.203     brouard  4102:     } /* End loop k */
1.126     brouard  4103:   }
                   4104:   delti[theta]=delts;
                   4105:   return res; 
                   4106:   
                   4107: }
                   4108: 
1.203     brouard  4109: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4110: {
                   4111:   int i;
1.164     brouard  4112:   int l=1, lmax=20;
1.126     brouard  4113:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4114:   double p2[MAXPARM+1];
1.203     brouard  4115:   int k, kmax=1;
                   4116:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4117: 
                   4118:   int firstime=0;
1.203     brouard  4119:   
1.126     brouard  4120:   fx=func(x);
1.203     brouard  4121:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4122:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4123:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4124:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4125:     k1=func(p2)-fx;
                   4126:   
1.203     brouard  4127:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4128:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4129:     k2=func(p2)-fx;
                   4130:   
1.203     brouard  4131:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4132:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4133:     k3=func(p2)-fx;
                   4134:   
1.203     brouard  4135:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4136:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4137:     k4=func(p2)-fx;
1.203     brouard  4138:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4139:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4140:       firstime=1;
1.203     brouard  4141:       kmax=kmax+10;
1.208     brouard  4142:     }
                   4143:     if(kmax >=10 || firstime ==1){
1.246     brouard  4144:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4145:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4146:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4147:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4148:     }
                   4149: #ifdef DEBUGHESSIJ
                   4150:     v1=hess[thetai][thetai];
                   4151:     v2=hess[thetaj][thetaj];
                   4152:     cv12=res;
                   4153:     /* Computing eigen value of Hessian matrix */
                   4154:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4155:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4156:     if ((lc2 <0) || (lc1 <0) ){
                   4157:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4158:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4159:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4160:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4161:     }
1.126     brouard  4162: #endif
                   4163:   }
                   4164:   return res;
                   4165: }
                   4166: 
1.203     brouard  4167:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4168: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4169: /* { */
                   4170: /*   int i; */
                   4171: /*   int l=1, lmax=20; */
                   4172: /*   double k1,k2,k3,k4,res,fx; */
                   4173: /*   double p2[MAXPARM+1]; */
                   4174: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4175: /*   int k=0,kmax=10; */
                   4176: /*   double l1; */
                   4177:   
                   4178: /*   fx=func(x); */
                   4179: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4180: /*     l1=pow(10,l); */
                   4181: /*     delts=delt; */
                   4182: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4183: /*       delt = delti*(l1*k); */
                   4184: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4185: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4186: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4187: /*       k1=func(p2)-fx; */
                   4188:       
                   4189: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4190: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4191: /*       k2=func(p2)-fx; */
                   4192:       
                   4193: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4194: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4195: /*       k3=func(p2)-fx; */
                   4196:       
                   4197: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4198: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4199: /*       k4=func(p2)-fx; */
                   4200: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4201: /* #ifdef DEBUGHESSIJ */
                   4202: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4203: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4204: /* #endif */
                   4205: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4206: /*     k=kmax; */
                   4207: /*       } */
                   4208: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4209: /*     k=kmax; l=lmax*10; */
                   4210: /*       } */
                   4211: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4212: /*     delts=delt; */
                   4213: /*       } */
                   4214: /*     } /\* End loop k *\/ */
                   4215: /*   } */
                   4216: /*   delti[theta]=delts; */
                   4217: /*   return res;  */
                   4218: /* } */
                   4219: 
                   4220: 
1.126     brouard  4221: /************** Inverse of matrix **************/
                   4222: void ludcmp(double **a, int n, int *indx, double *d) 
                   4223: { 
                   4224:   int i,imax,j,k; 
                   4225:   double big,dum,sum,temp; 
                   4226:   double *vv; 
                   4227:  
                   4228:   vv=vector(1,n); 
                   4229:   *d=1.0; 
                   4230:   for (i=1;i<=n;i++) { 
                   4231:     big=0.0; 
                   4232:     for (j=1;j<=n;j++) 
                   4233:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4234:     if (big == 0.0){
                   4235:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4236:       for (j=1;j<=n;j++) {
                   4237:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4238:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4239:       }
                   4240:       fflush(ficlog);
                   4241:       fclose(ficlog);
                   4242:       nrerror("Singular matrix in routine ludcmp"); 
                   4243:     }
1.126     brouard  4244:     vv[i]=1.0/big; 
                   4245:   } 
                   4246:   for (j=1;j<=n;j++) { 
                   4247:     for (i=1;i<j;i++) { 
                   4248:       sum=a[i][j]; 
                   4249:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4250:       a[i][j]=sum; 
                   4251:     } 
                   4252:     big=0.0; 
                   4253:     for (i=j;i<=n;i++) { 
                   4254:       sum=a[i][j]; 
                   4255:       for (k=1;k<j;k++) 
                   4256:        sum -= a[i][k]*a[k][j]; 
                   4257:       a[i][j]=sum; 
                   4258:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4259:        big=dum; 
                   4260:        imax=i; 
                   4261:       } 
                   4262:     } 
                   4263:     if (j != imax) { 
                   4264:       for (k=1;k<=n;k++) { 
                   4265:        dum=a[imax][k]; 
                   4266:        a[imax][k]=a[j][k]; 
                   4267:        a[j][k]=dum; 
                   4268:       } 
                   4269:       *d = -(*d); 
                   4270:       vv[imax]=vv[j]; 
                   4271:     } 
                   4272:     indx[j]=imax; 
                   4273:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4274:     if (j != n) { 
                   4275:       dum=1.0/(a[j][j]); 
                   4276:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4277:     } 
                   4278:   } 
                   4279:   free_vector(vv,1,n);  /* Doesn't work */
                   4280: ;
                   4281: } 
                   4282: 
                   4283: void lubksb(double **a, int n, int *indx, double b[]) 
                   4284: { 
                   4285:   int i,ii=0,ip,j; 
                   4286:   double sum; 
                   4287:  
                   4288:   for (i=1;i<=n;i++) { 
                   4289:     ip=indx[i]; 
                   4290:     sum=b[ip]; 
                   4291:     b[ip]=b[i]; 
                   4292:     if (ii) 
                   4293:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4294:     else if (sum) ii=i; 
                   4295:     b[i]=sum; 
                   4296:   } 
                   4297:   for (i=n;i>=1;i--) { 
                   4298:     sum=b[i]; 
                   4299:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4300:     b[i]=sum/a[i][i]; 
                   4301:   } 
                   4302: } 
                   4303: 
                   4304: void pstamp(FILE *fichier)
                   4305: {
1.196     brouard  4306:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4307: }
                   4308: 
1.253     brouard  4309: 
                   4310: 
1.126     brouard  4311: /************ Frequencies ********************/
1.251     brouard  4312: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4313:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4314:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4315: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4316:   
1.265     brouard  4317:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4318:   int iind=0, iage=0;
                   4319:   int mi; /* Effective wave */
                   4320:   int first;
                   4321:   double ***freq; /* Frequencies */
1.268     brouard  4322:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4323:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.226     brouard  4324:   double *meanq;
                   4325:   double **meanqt;
                   4326:   double *pp, **prop, *posprop, *pospropt;
                   4327:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4328:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4329:   double agebegin, ageend;
                   4330:     
                   4331:   pp=vector(1,nlstate);
1.251     brouard  4332:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4333:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4334:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4335:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4336:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4337:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4338:   strcpy(fileresp,"P_");
                   4339:   strcat(fileresp,fileresu);
                   4340:   /*strcat(fileresphtm,fileresu);*/
                   4341:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4342:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4343:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4344:     exit(0);
                   4345:   }
1.240     brouard  4346:   
1.226     brouard  4347:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4348:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4349:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4350:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4351:     fflush(ficlog);
                   4352:     exit(70); 
                   4353:   }
                   4354:   else{
                   4355:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4356: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4357: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4358:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4359:   }
1.237     brouard  4360:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4361:   
1.226     brouard  4362:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4363:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4364:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4365:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4366:     fflush(ficlog);
                   4367:     exit(70); 
1.240     brouard  4368:   } else{
1.226     brouard  4369:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4370: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4371: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4372:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4373:   }
1.240     brouard  4374:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4375:   
1.253     brouard  4376:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4377:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4378:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4379:   j1=0;
1.126     brouard  4380:   
1.227     brouard  4381:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4382:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4383:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4384:   
                   4385:   
1.226     brouard  4386:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4387:      reference=low_education V1=0,V2=0
                   4388:      med_educ                V1=1 V2=0, 
                   4389:      high_educ               V1=0 V2=1
                   4390:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4391:   */
1.249     brouard  4392:   dateintsum=0;
                   4393:   k2cpt=0;
                   4394: 
1.253     brouard  4395:   if(cptcoveff == 0 )
1.265     brouard  4396:     nl=1;  /* Constant and age model only */
1.253     brouard  4397:   else
                   4398:     nl=2;
1.265     brouard  4399: 
                   4400:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4401:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4402:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4403:    *     freq[s1][s2][iage] =0.
                   4404:    *     Loop on iind
                   4405:    *       ++freq[s1][s2][iage] weighted
                   4406:    *     end iind
                   4407:    *     if covariate and j!0
                   4408:    *       headers Variable on one line
                   4409:    *     endif cov j!=0
                   4410:    *     header of frequency table by age
                   4411:    *     Loop on age
                   4412:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4413:    *       pos+=freq[s1][s2][iage] weighted
                   4414:    *       Loop on s1 initial state
                   4415:    *         fprintf(ficresp
                   4416:    *       end s1
                   4417:    *     end age
                   4418:    *     if j!=0 computes starting values
                   4419:    *     end compute starting values
                   4420:    *   end j1
                   4421:    * end nl 
                   4422:    */
1.253     brouard  4423:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4424:     if(nj==1)
                   4425:       j=0;  /* First pass for the constant */
1.265     brouard  4426:     else{
1.253     brouard  4427:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4428:     }
1.251     brouard  4429:     first=1;
1.265     brouard  4430:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4431:       posproptt=0.;
                   4432:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4433:        scanf("%d", i);*/
                   4434:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4435:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4436:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4437:            freq[i][s2][m]=0;
1.251     brouard  4438:       
                   4439:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4440:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4441:          prop[i][m]=0;
                   4442:        posprop[i]=0;
                   4443:        pospropt[i]=0;
                   4444:       }
                   4445:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4446:       /*   meanq[z1]+=0.; */
                   4447:       /*   for(m=1;m<=lastpass;m++){ */
                   4448:       /*       meanqt[m][z1]=0.; */
                   4449:       /*   } */
                   4450:       /* } */
                   4451:       
                   4452:       /* dateintsum=0; */
                   4453:       /* k2cpt=0; */
                   4454:       
1.265     brouard  4455:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4456:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4457:        bool=1;
                   4458:        if(j !=0){
                   4459:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4460:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4461:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4462:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4463:              /* } */
                   4464:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4465:                /* if(Tvaraff[z1] ==-20){ */
                   4466:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4467:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4468:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4469:                /* }else  */
                   4470:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4471:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4472:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4473:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4474:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4475:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4476:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4477:                } /* Onlyf fixed */
                   4478:              } /* end z1 */
                   4479:            } /* cptcovn > 0 */
                   4480:          } /* end any */
                   4481:        }/* end j==0 */
1.265     brouard  4482:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4483:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4484:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4485:            m=mw[mi][iind];
                   4486:            if(j!=0){
                   4487:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4488:                for (z1=1; z1<=cptcoveff; z1++) {
                   4489:                  if( Fixed[Tmodelind[z1]]==1){
                   4490:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4491:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4492:                                                                                      value is -1, we don't select. It differs from the 
                   4493:                                                                                      constant and age model which counts them. */
                   4494:                      bool=0; /* not selected */
                   4495:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4496:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4497:                      bool=0;
                   4498:                    }
                   4499:                  }
                   4500:                }
                   4501:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4502:            } /* end j==0 */
                   4503:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4504:            if(bool==1){
                   4505:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4506:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4507:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4508:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4509:              if(m >=firstpass && m <=lastpass){
                   4510:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4511:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4512:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4513:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4514:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4515:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4516:                if (m<lastpass) {
                   4517:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4518:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4519:                  if(s[m][iind]==-1)
                   4520:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4521:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4522:                  /* if((int)agev[m][iind] == 55) */
                   4523:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4524:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4525:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4526:                }
1.251     brouard  4527:              } /* end if between passes */  
                   4528:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4529:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4530:                k2cpt++;
                   4531:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4532:              }
1.251     brouard  4533:            }else{
                   4534:              bool=1;
                   4535:            }/* end bool 2 */
                   4536:          } /* end m */
                   4537:        } /* end bool */
                   4538:       } /* end iind = 1 to imx */
                   4539:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4540:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4541:       
                   4542:       
                   4543:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4544:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4545:         pstamp(ficresp);
1.251     brouard  4546:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4547:         pstamp(ficresp);
1.251     brouard  4548:        printf( "\n#********** Variable "); 
                   4549:        fprintf(ficresp, "\n#********** Variable "); 
                   4550:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4551:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4552:        fprintf(ficlog, "\n#********** Variable "); 
                   4553:        for (z1=1; z1<=cptcoveff; z1++){
                   4554:          if(!FixedV[Tvaraff[z1]]){
                   4555:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4556:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4557:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4558:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4559:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4560:          }else{
1.251     brouard  4561:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4562:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4563:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4564:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4565:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4566:          }
                   4567:        }
                   4568:        printf( "**********\n#");
                   4569:        fprintf(ficresp, "**********\n#");
                   4570:        fprintf(ficresphtm, "**********</h3>\n");
                   4571:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4572:        fprintf(ficlog, "**********\n");
                   4573:       }
                   4574:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4575:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4576:         fprintf(ficresp, " Age");
                   4577:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4578:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4579:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4580:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4581:       }
1.265     brouard  4582:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4583:       fprintf(ficresphtm, "\n");
                   4584:       
                   4585:       /* Header of frequency table by age */
                   4586:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4587:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4588:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4589:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4590:          if(s2!=0 && m!=0)
                   4591:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4592:        }
1.226     brouard  4593:       }
1.251     brouard  4594:       fprintf(ficresphtmfr, "\n");
                   4595:     
                   4596:       /* For each age */
                   4597:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4598:        fprintf(ficresphtm,"<tr>");
                   4599:        if(iage==iagemax+1){
                   4600:          fprintf(ficlog,"1");
                   4601:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4602:        }else if(iage==iagemax+2){
                   4603:          fprintf(ficlog,"0");
                   4604:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4605:        }else if(iage==iagemax+3){
                   4606:          fprintf(ficlog,"Total");
                   4607:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4608:        }else{
1.240     brouard  4609:          if(first==1){
1.251     brouard  4610:            first=0;
                   4611:            printf("See log file for details...\n");
                   4612:          }
                   4613:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4614:          fprintf(ficlog,"Age %d", iage);
                   4615:        }
1.265     brouard  4616:        for(s1=1; s1 <=nlstate ; s1++){
                   4617:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4618:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4619:        }
1.265     brouard  4620:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4621:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4622:            pos += freq[s1][m][iage];
                   4623:          if(pp[s1]>=1.e-10){
1.251     brouard  4624:            if(first==1){
1.265     brouard  4625:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4626:            }
1.265     brouard  4627:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4628:          }else{
                   4629:            if(first==1)
1.265     brouard  4630:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4631:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4632:          }
                   4633:        }
                   4634:       
1.265     brouard  4635:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4636:          /* posprop[s1]=0; */
                   4637:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4638:            pp[s1] += freq[s1][m][iage];
                   4639:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4640:       
                   4641:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4642:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4643:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4644:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4645:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4646:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4647:        }
                   4648:        
                   4649:        /* Writing ficresp */
                   4650:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4651:           if( iage <= iagemax){
                   4652:            fprintf(ficresp," %d",iage);
                   4653:           }
                   4654:         }else if( nj==2){
                   4655:           if( iage <= iagemax){
                   4656:            fprintf(ficresp," %d",iage);
                   4657:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4658:           }
1.240     brouard  4659:        }
1.265     brouard  4660:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4661:          if(pos>=1.e-5){
1.251     brouard  4662:            if(first==1)
1.265     brouard  4663:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4664:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4665:          }else{
                   4666:            if(first==1)
1.265     brouard  4667:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4668:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4669:          }
                   4670:          if( iage <= iagemax){
                   4671:            if(pos>=1.e-5){
1.265     brouard  4672:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4673:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4674:               }else if( nj==2){
                   4675:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4676:               }
                   4677:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4678:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4679:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4680:            } else{
                   4681:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4682:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4683:            }
1.240     brouard  4684:          }
1.265     brouard  4685:          pospropt[s1] +=posprop[s1];
                   4686:        } /* end loop s1 */
1.251     brouard  4687:        /* pospropt=0.; */
1.265     brouard  4688:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4689:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4690:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4691:              if(first==1){
1.265     brouard  4692:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4693:              }
1.265     brouard  4694:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4695:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4696:            }
1.265     brouard  4697:            if(s1!=0 && m!=0)
                   4698:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4699:          }
1.265     brouard  4700:        } /* end loop s1 */
1.251     brouard  4701:        posproptt=0.; 
1.265     brouard  4702:        for(s1=1; s1 <=nlstate; s1++){
                   4703:          posproptt += pospropt[s1];
1.251     brouard  4704:        }
                   4705:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4706:        fprintf(ficresphtm,"</tr>\n");
                   4707:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4708:          if(iage <= iagemax)
                   4709:            fprintf(ficresp,"\n");
1.240     brouard  4710:        }
1.251     brouard  4711:        if(first==1)
                   4712:          printf("Others in log...\n");
                   4713:        fprintf(ficlog,"\n");
                   4714:       } /* end loop age iage */
1.265     brouard  4715:       
1.251     brouard  4716:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4717:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4718:        if(posproptt < 1.e-5){
1.265     brouard  4719:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4720:        }else{
1.265     brouard  4721:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4722:        }
1.226     brouard  4723:       }
1.251     brouard  4724:       fprintf(ficresphtm,"</tr>\n");
                   4725:       fprintf(ficresphtm,"</table>\n");
                   4726:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4727:       if(posproptt < 1.e-5){
1.251     brouard  4728:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4729:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4730:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4731:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4732:        invalidvarcomb[j1]=1;
1.226     brouard  4733:       }else{
1.251     brouard  4734:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4735:        invalidvarcomb[j1]=0;
1.226     brouard  4736:       }
1.251     brouard  4737:       fprintf(ficresphtmfr,"</table>\n");
                   4738:       fprintf(ficlog,"\n");
                   4739:       if(j!=0){
                   4740:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4741:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4742:          for(k=1; k <=(nlstate+ndeath); k++){
                   4743:            if (k != i) {
1.265     brouard  4744:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4745:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4746:                  if(j1==1){ /* All dummy covariates to zero */
                   4747:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4748:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4749:                    printf("%d%d ",i,k);
                   4750:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4751:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4752:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4753:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4754:                  }
1.253     brouard  4755:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4756:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4757:                    x[iage]= (double)iage;
                   4758:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4759:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4760:                  }
1.268     brouard  4761:                  /* Some are not finite, but linreg will ignore these ages */
                   4762:                  no=0;
1.253     brouard  4763:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4764:                  pstart[s1]=b;
                   4765:                  pstart[s1-1]=a;
1.252     brouard  4766:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4767:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4768:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4769:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4770:                  printf("%d%d ",i,k);
                   4771:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4772:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4773:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4774:                  ;
                   4775:                }
                   4776:                /* printf("%12.7f )", param[i][jj][k]); */
                   4777:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4778:                s1++; 
1.251     brouard  4779:              } /* end jj */
                   4780:            } /* end k!= i */
                   4781:          } /* end k */
1.265     brouard  4782:        } /* end i, s1 */
1.251     brouard  4783:       } /* end j !=0 */
                   4784:     } /* end selected combination of covariate j1 */
                   4785:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4786:       printf("#Freqsummary: Starting values for the constants:\n");
                   4787:       fprintf(ficlog,"\n");
1.265     brouard  4788:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4789:        for(k=1; k <=(nlstate+ndeath); k++){
                   4790:          if (k != i) {
                   4791:            printf("%d%d ",i,k);
                   4792:            fprintf(ficlog,"%d%d ",i,k);
                   4793:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4794:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4795:              if(jj==1){ /* Age has to be done */
1.265     brouard  4796:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4797:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4798:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4799:              }
                   4800:              /* printf("%12.7f )", param[i][jj][k]); */
                   4801:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4802:              s1++; 
1.250     brouard  4803:            }
1.251     brouard  4804:            printf("\n");
                   4805:            fprintf(ficlog,"\n");
1.250     brouard  4806:          }
                   4807:        }
                   4808:       }
1.251     brouard  4809:       printf("#Freqsummary\n");
                   4810:       fprintf(ficlog,"\n");
1.265     brouard  4811:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4812:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4813:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4814:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4815:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4816:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4817:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4818:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4819:          /* } */
                   4820:        }
1.265     brouard  4821:       } /* end loop s1 */
1.251     brouard  4822:       
                   4823:       printf("\n");
                   4824:       fprintf(ficlog,"\n");
                   4825:     } /* end j=0 */
1.249     brouard  4826:   } /* end j */
1.252     brouard  4827: 
1.253     brouard  4828:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4829:     for(i=1, jk=1; i <=nlstate; i++){
                   4830:       for(j=1; j <=nlstate+ndeath; j++){
                   4831:        if(j!=i){
                   4832:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4833:          printf("%1d%1d",i,j);
                   4834:          fprintf(ficparo,"%1d%1d",i,j);
                   4835:          for(k=1; k<=ncovmodel;k++){
                   4836:            /*    printf(" %lf",param[i][j][k]); */
                   4837:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4838:            p[jk]=pstart[jk];
                   4839:            printf(" %f ",pstart[jk]);
                   4840:            fprintf(ficparo," %f ",pstart[jk]);
                   4841:            jk++;
                   4842:          }
                   4843:          printf("\n");
                   4844:          fprintf(ficparo,"\n");
                   4845:        }
                   4846:       }
                   4847:     }
                   4848:   } /* end mle=-2 */
1.226     brouard  4849:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4850:   
1.226     brouard  4851:   fclose(ficresp);
                   4852:   fclose(ficresphtm);
                   4853:   fclose(ficresphtmfr);
                   4854:   free_vector(meanq,1,nqfveff);
                   4855:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4856:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4857:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4858:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4859:   free_vector(pospropt,1,nlstate);
                   4860:   free_vector(posprop,1,nlstate);
1.251     brouard  4861:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4862:   free_vector(pp,1,nlstate);
                   4863:   /* End of freqsummary */
                   4864: }
1.126     brouard  4865: 
1.268     brouard  4866: /* Simple linear regression */
                   4867: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4868: 
                   4869:   /* y=a+bx regression */
                   4870:   double   sumx = 0.0;                        /* sum of x                      */
                   4871:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4872:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4873:   double   sumy = 0.0;                        /* sum of y                      */
                   4874:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4875:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4876:   double yhat;
                   4877:   
                   4878:   double denom=0;
                   4879:   int i;
                   4880:   int ne=*no;
                   4881:   
                   4882:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4883:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4884:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4885:       continue;
                   4886:     }
                   4887:     ne=ne+1;
                   4888:     sumx  += x[i];       
                   4889:     sumx2 += x[i]*x[i];  
                   4890:     sumxy += x[i] * y[i];
                   4891:     sumy  += y[i];      
                   4892:     sumy2 += y[i]*y[i]; 
                   4893:     denom = (ne * sumx2 - sumx*sumx);
                   4894:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4895:   } 
                   4896:   
                   4897:   denom = (ne * sumx2 - sumx*sumx);
                   4898:   if (denom == 0) {
                   4899:     // vertical, slope m is infinity
                   4900:     *b = INFINITY;
                   4901:     *a = 0;
                   4902:     if (r) *r = 0;
                   4903:     return 1;
                   4904:   }
                   4905:   
                   4906:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4907:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4908:   if (r!=NULL) {
                   4909:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4910:       sqrt((sumx2 - sumx*sumx/ne) *
                   4911:           (sumy2 - sumy*sumy/ne));
                   4912:   }
                   4913:   *no=ne;
                   4914:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4915:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4916:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4917:       continue;
                   4918:     }
                   4919:     ne=ne+1;
                   4920:     yhat = y[i] - *a -*b* x[i];
                   4921:     sume2  += yhat * yhat ;       
                   4922:     
                   4923:     denom = (ne * sumx2 - sumx*sumx);
                   4924:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4925:   } 
                   4926:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   4927:   *sa= *sb * sqrt(sumx2/ne);
                   4928:   
                   4929:   return 0; 
                   4930: }
                   4931: 
1.126     brouard  4932: /************ Prevalence ********************/
1.227     brouard  4933: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4934: {  
                   4935:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4936:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4937:      We still use firstpass and lastpass as another selection.
                   4938:   */
1.126     brouard  4939:  
1.227     brouard  4940:   int i, m, jk, j1, bool, z1,j, iv;
                   4941:   int mi; /* Effective wave */
                   4942:   int iage;
                   4943:   double agebegin, ageend;
                   4944: 
                   4945:   double **prop;
                   4946:   double posprop; 
                   4947:   double  y2; /* in fractional years */
                   4948:   int iagemin, iagemax;
                   4949:   int first; /** to stop verbosity which is redirected to log file */
                   4950: 
                   4951:   iagemin= (int) agemin;
                   4952:   iagemax= (int) agemax;
                   4953:   /*pp=vector(1,nlstate);*/
1.251     brouard  4954:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4955:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4956:   j1=0;
1.222     brouard  4957:   
1.227     brouard  4958:   /*j=cptcoveff;*/
                   4959:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4960:   
1.227     brouard  4961:   first=1;
                   4962:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4963:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4964:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4965:        prop[i][iage]=0.0;
                   4966:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4967:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4968:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4969:     
                   4970:     for (i=1; i<=imx; i++) { /* Each individual */
                   4971:       bool=1;
                   4972:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4973:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4974:        m=mw[mi][i];
                   4975:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4976:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4977:        for (z1=1; z1<=cptcoveff; z1++){
                   4978:          if( Fixed[Tmodelind[z1]]==1){
                   4979:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4980:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4981:              bool=0;
                   4982:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4983:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4984:              bool=0;
                   4985:            }
                   4986:        }
                   4987:        if(bool==1){ /* Otherwise we skip that wave/person */
                   4988:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   4989:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   4990:          if(m >=firstpass && m <=lastpass){
                   4991:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   4992:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   4993:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   4994:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  4995:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  4996:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   4997:                exit(1);
                   4998:              }
                   4999:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5000:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5001:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5002:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5003:              } /* end valid statuses */ 
                   5004:            } /* end selection of dates */
                   5005:          } /* end selection of waves */
                   5006:        } /* end bool */
                   5007:       } /* end wave */
                   5008:     } /* end individual */
                   5009:     for(i=iagemin; i <= iagemax+3; i++){  
                   5010:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5011:        posprop += prop[jk][i]; 
                   5012:       } 
                   5013:       
                   5014:       for(jk=1; jk <=nlstate ; jk++){      
                   5015:        if( i <=  iagemax){ 
                   5016:          if(posprop>=1.e-5){ 
                   5017:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5018:          } else{
                   5019:            if(first==1){
                   5020:              first=0;
1.266     brouard  5021:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5022:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5023:            }else{
                   5024:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5025:            }
                   5026:          }
                   5027:        } 
                   5028:       }/* end jk */ 
                   5029:     }/* end i */ 
1.222     brouard  5030:      /*} *//* end i1 */
1.227     brouard  5031:   } /* end j1 */
1.222     brouard  5032:   
1.227     brouard  5033:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5034:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5035:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5036: }  /* End of prevalence */
1.126     brouard  5037: 
                   5038: /************* Waves Concatenation ***************/
                   5039: 
                   5040: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5041: {
                   5042:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5043:      Death is a valid wave (if date is known).
                   5044:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5045:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5046:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5047:   */
1.126     brouard  5048: 
1.224     brouard  5049:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5050:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5051:      double sum=0., jmean=0.;*/
1.224     brouard  5052:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5053:   int j, k=0,jk, ju, jl;
                   5054:   double sum=0.;
                   5055:   first=0;
1.214     brouard  5056:   firstwo=0;
1.217     brouard  5057:   firsthree=0;
1.218     brouard  5058:   firstfour=0;
1.164     brouard  5059:   jmin=100000;
1.126     brouard  5060:   jmax=-1;
                   5061:   jmean=0.;
1.224     brouard  5062: 
                   5063: /* Treating live states */
1.214     brouard  5064:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5065:     mi=0;  /* First valid wave */
1.227     brouard  5066:     mli=0; /* Last valid wave */
1.126     brouard  5067:     m=firstpass;
1.214     brouard  5068:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5069:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5070:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5071:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5072:        mw[++mi][i]=m;
                   5073:        mli=m;
1.224     brouard  5074:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5075:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5076:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5077:       }
1.227     brouard  5078:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5079: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5080:        break;
1.224     brouard  5081: #else
1.227     brouard  5082:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5083:          if(firsthree == 0){
1.262     brouard  5084:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5085:            firsthree=1;
                   5086:          }
1.262     brouard  5087:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5088:          mw[++mi][i]=m;
                   5089:          mli=m;
                   5090:        }
                   5091:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5092:          nbwarn++;
                   5093:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5094:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5095:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5096:          }
                   5097:          break;
                   5098:        }
                   5099:        break;
1.224     brouard  5100: #endif
1.227     brouard  5101:       }/* End m >= lastpass */
1.126     brouard  5102:     }/* end while */
1.224     brouard  5103: 
1.227     brouard  5104:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5105:     /* After last pass */
1.224     brouard  5106: /* Treating death states */
1.214     brouard  5107:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5108:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5109:       /* } */
1.126     brouard  5110:       mi++;    /* Death is another wave */
                   5111:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5112:       /* Only death is a correct wave */
1.126     brouard  5113:       mw[mi][i]=m;
1.257     brouard  5114:     } /* else not in a death state */
1.224     brouard  5115: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5116:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5117:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5118:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5119:          nbwarn++;
                   5120:          if(firstfiv==0){
                   5121:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5122:            firstfiv=1;
                   5123:          }else{
                   5124:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5125:          }
                   5126:        }else{ /* Death occured afer last wave potential bias */
                   5127:          nberr++;
                   5128:          if(firstwo==0){
1.257     brouard  5129:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5130:            firstwo=1;
                   5131:          }
1.257     brouard  5132:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5133:        }
1.257     brouard  5134:       }else{ /* if date of interview is unknown */
1.227     brouard  5135:        /* death is known but not confirmed by death status at any wave */
                   5136:        if(firstfour==0){
                   5137:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5138:          firstfour=1;
                   5139:        }
                   5140:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5141:       }
1.224     brouard  5142:     } /* end if date of death is known */
                   5143: #endif
                   5144:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5145:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5146:     if(mi==0){
                   5147:       nbwarn++;
                   5148:       if(first==0){
1.227     brouard  5149:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5150:        first=1;
1.126     brouard  5151:       }
                   5152:       if(first==1){
1.227     brouard  5153:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5154:       }
                   5155:     } /* end mi==0 */
                   5156:   } /* End individuals */
1.214     brouard  5157:   /* wav and mw are no more changed */
1.223     brouard  5158:        
1.214     brouard  5159:   
1.126     brouard  5160:   for(i=1; i<=imx; i++){
                   5161:     for(mi=1; mi<wav[i];mi++){
                   5162:       if (stepm <=0)
1.227     brouard  5163:        dh[mi][i]=1;
1.126     brouard  5164:       else{
1.260     brouard  5165:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5166:          if (agedc[i] < 2*AGESUP) {
                   5167:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5168:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5169:            else if(j<0){
                   5170:              nberr++;
                   5171:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5172:              j=1; /* Temporary Dangerous patch */
                   5173:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5174:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5175:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5176:            }
                   5177:            k=k+1;
                   5178:            if (j >= jmax){
                   5179:              jmax=j;
                   5180:              ijmax=i;
                   5181:            }
                   5182:            if (j <= jmin){
                   5183:              jmin=j;
                   5184:              ijmin=i;
                   5185:            }
                   5186:            sum=sum+j;
                   5187:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5188:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5189:          }
                   5190:        }
                   5191:        else{
                   5192:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5193: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5194:                                        
1.227     brouard  5195:          k=k+1;
                   5196:          if (j >= jmax) {
                   5197:            jmax=j;
                   5198:            ijmax=i;
                   5199:          }
                   5200:          else if (j <= jmin){
                   5201:            jmin=j;
                   5202:            ijmin=i;
                   5203:          }
                   5204:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5205:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5206:          if(j<0){
                   5207:            nberr++;
                   5208:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5209:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5210:          }
                   5211:          sum=sum+j;
                   5212:        }
                   5213:        jk= j/stepm;
                   5214:        jl= j -jk*stepm;
                   5215:        ju= j -(jk+1)*stepm;
                   5216:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5217:          if(jl==0){
                   5218:            dh[mi][i]=jk;
                   5219:            bh[mi][i]=0;
                   5220:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5221:                  * to avoid the price of an extra matrix product in likelihood */
                   5222:            dh[mi][i]=jk+1;
                   5223:            bh[mi][i]=ju;
                   5224:          }
                   5225:        }else{
                   5226:          if(jl <= -ju){
                   5227:            dh[mi][i]=jk;
                   5228:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5229:                                 * is higher than the multiple of stepm and negative otherwise.
                   5230:                                 */
                   5231:          }
                   5232:          else{
                   5233:            dh[mi][i]=jk+1;
                   5234:            bh[mi][i]=ju;
                   5235:          }
                   5236:          if(dh[mi][i]==0){
                   5237:            dh[mi][i]=1; /* At least one step */
                   5238:            bh[mi][i]=ju; /* At least one step */
                   5239:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5240:          }
                   5241:        } /* end if mle */
1.126     brouard  5242:       }
                   5243:     } /* end wave */
                   5244:   }
                   5245:   jmean=sum/k;
                   5246:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5247:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5248: }
1.126     brouard  5249: 
                   5250: /*********** Tricode ****************************/
1.220     brouard  5251:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5252:  {
                   5253:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5254:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5255:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5256:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5257:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5258:     */
1.130     brouard  5259: 
1.242     brouard  5260:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5261:    int modmaxcovj=0; /* Modality max of covariates j */
                   5262:    int cptcode=0; /* Modality max of covariates j */
                   5263:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5264: 
                   5265: 
1.242     brouard  5266:    /* cptcoveff=0;  */
                   5267:    /* *cptcov=0; */
1.126     brouard  5268:  
1.242     brouard  5269:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5270: 
1.242     brouard  5271:    /* Loop on covariates without age and products and no quantitative variable */
                   5272:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5273:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5274:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5275:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5276:        switch(Fixed[k]) {
                   5277:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5278:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5279:           ij=(int)(covar[Tvar[k]][i]);
                   5280:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5281:            * If product of Vn*Vm, still boolean *:
                   5282:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5283:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5284:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5285:              modality of the nth covariate of individual i. */
                   5286:           if (ij > modmaxcovj)
                   5287:             modmaxcovj=ij; 
                   5288:           else if (ij < modmincovj) 
                   5289:             modmincovj=ij; 
                   5290:           if ((ij < -1) && (ij > NCOVMAX)){
                   5291:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5292:             exit(1);
                   5293:           }else
                   5294:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5295:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5296:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5297:           /* getting the maximum value of the modality of the covariate
                   5298:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5299:              female ies 1, then modmaxcovj=1.
                   5300:           */
                   5301:         } /* end for loop on individuals i */
                   5302:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5303:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5304:         cptcode=modmaxcovj;
                   5305:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5306:         /*for (i=0; i<=cptcode; i++) {*/
                   5307:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5308:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5309:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5310:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5311:             if( j != -1){
                   5312:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5313:                                  covariate for which somebody answered excluding 
                   5314:                                  undefined. Usually 2: 0 and 1. */
                   5315:             }
                   5316:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5317:                                     covariate for which somebody answered including 
                   5318:                                     undefined. Usually 3: -1, 0 and 1. */
                   5319:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5320:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5321:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5322:                        
1.242     brouard  5323:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5324:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5325:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5326:         /* modmincovj=3; modmaxcovj = 7; */
                   5327:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5328:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5329:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5330:         /* nbcode[Tvar[j]][ij]=k; */
                   5331:         /* nbcode[Tvar[j]][1]=0; */
                   5332:         /* nbcode[Tvar[j]][2]=1; */
                   5333:         /* nbcode[Tvar[j]][3]=2; */
                   5334:         /* To be continued (not working yet). */
                   5335:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5336:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5337:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5338:             break;
                   5339:           }
                   5340:           ij++;
                   5341:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5342:           cptcode = ij; /* New max modality for covar j */
                   5343:         } /* end of loop on modality i=-1 to 1 or more */
                   5344:         break;
                   5345:        case 1: /* Testing on varying covariate, could be simple and
                   5346:                * should look at waves or product of fixed *
                   5347:                * varying. No time to test -1, assuming 0 and 1 only */
                   5348:         ij=0;
                   5349:         for(i=0; i<=1;i++){
                   5350:           nbcode[Tvar[k]][++ij]=i;
                   5351:         }
                   5352:         break;
                   5353:        default:
                   5354:         break;
                   5355:        } /* end switch */
                   5356:      } /* end dummy test */
                   5357:     
                   5358:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5359:      /*        /\*recode from 0 *\/ */
                   5360:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5361:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5362:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5363:      /*        } */
                   5364:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5365:      /*        if (ij > ncodemax[j]) { */
                   5366:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5367:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5368:      /*          break; */
                   5369:      /*        } */
                   5370:      /*   }  /\* end of loop on modality k *\/ */
                   5371:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5372:   
                   5373:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5374:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5375:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5376:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5377:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5378:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5379:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5380:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5381:   
                   5382:    ij=0;
                   5383:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5384:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5385:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5386:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5387:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5388:        /* If product not in single variable we don't print results */
                   5389:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5390:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5391:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5392:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5393:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5394:        if(Fixed[k]!=0)
                   5395:         anyvaryingduminmodel=1;
                   5396:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5397:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5398:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5399:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5400:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5401:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5402:      } 
                   5403:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5404:    /* ij--; */
                   5405:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5406:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5407:                * because they can be excluded from the model and real
                   5408:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5409:    for(j=ij+1; j<= cptcovt; j++){
                   5410:      Tvaraff[j]=0;
                   5411:      Tmodelind[j]=0;
                   5412:    }
                   5413:    for(j=ntveff+1; j<= cptcovt; j++){
                   5414:      TmodelInvind[j]=0;
                   5415:    }
                   5416:    /* To be sorted */
                   5417:    ;
                   5418:  }
1.126     brouard  5419: 
1.145     brouard  5420: 
1.126     brouard  5421: /*********** Health Expectancies ****************/
                   5422: 
1.235     brouard  5423:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5424: 
                   5425: {
                   5426:   /* Health expectancies, no variances */
1.164     brouard  5427:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5428:   int nhstepma, nstepma; /* Decreasing with age */
                   5429:   double age, agelim, hf;
                   5430:   double ***p3mat;
                   5431:   double eip;
                   5432: 
1.238     brouard  5433:   /* pstamp(ficreseij); */
1.126     brouard  5434:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5435:   fprintf(ficreseij,"# Age");
                   5436:   for(i=1; i<=nlstate;i++){
                   5437:     for(j=1; j<=nlstate;j++){
                   5438:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5439:     }
                   5440:     fprintf(ficreseij," e%1d. ",i);
                   5441:   }
                   5442:   fprintf(ficreseij,"\n");
                   5443: 
                   5444:   
                   5445:   if(estepm < stepm){
                   5446:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5447:   }
                   5448:   else  hstepm=estepm;   
                   5449:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5450:    * This is mainly to measure the difference between two models: for example
                   5451:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5452:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5453:    * progression in between and thus overestimating or underestimating according
                   5454:    * to the curvature of the survival function. If, for the same date, we 
                   5455:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5456:    * to compare the new estimate of Life expectancy with the same linear 
                   5457:    * hypothesis. A more precise result, taking into account a more precise
                   5458:    * curvature will be obtained if estepm is as small as stepm. */
                   5459: 
                   5460:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5461:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5462:      nhstepm is the number of hstepm from age to agelim 
                   5463:      nstepm is the number of stepm from age to agelin. 
                   5464:      Look at hpijx to understand the reason of that which relies in memory size
                   5465:      and note for a fixed period like estepm months */
                   5466:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5467:      survival function given by stepm (the optimization length). Unfortunately it
                   5468:      means that if the survival funtion is printed only each two years of age and if
                   5469:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5470:      results. So we changed our mind and took the option of the best precision.
                   5471:   */
                   5472:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5473: 
                   5474:   agelim=AGESUP;
                   5475:   /* If stepm=6 months */
                   5476:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5477:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5478:     
                   5479: /* nhstepm age range expressed in number of stepm */
                   5480:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5481:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5482:   /* if (stepm >= YEARM) hstepm=1;*/
                   5483:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5484:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5485: 
                   5486:   for (age=bage; age<=fage; age ++){ 
                   5487:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5488:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5489:     /* if (stepm >= YEARM) hstepm=1;*/
                   5490:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5491: 
                   5492:     /* If stepm=6 months */
                   5493:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5494:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5495:     
1.235     brouard  5496:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5497:     
                   5498:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5499:     
                   5500:     printf("%d|",(int)age);fflush(stdout);
                   5501:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5502:     
                   5503:     /* Computing expectancies */
                   5504:     for(i=1; i<=nlstate;i++)
                   5505:       for(j=1; j<=nlstate;j++)
                   5506:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5507:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5508:          
                   5509:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5510: 
                   5511:        }
                   5512: 
                   5513:     fprintf(ficreseij,"%3.0f",age );
                   5514:     for(i=1; i<=nlstate;i++){
                   5515:       eip=0;
                   5516:       for(j=1; j<=nlstate;j++){
                   5517:        eip +=eij[i][j][(int)age];
                   5518:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5519:       }
                   5520:       fprintf(ficreseij,"%9.4f", eip );
                   5521:     }
                   5522:     fprintf(ficreseij,"\n");
                   5523:     
                   5524:   }
                   5525:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5526:   printf("\n");
                   5527:   fprintf(ficlog,"\n");
                   5528:   
                   5529: }
                   5530: 
1.235     brouard  5531:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5532: 
                   5533: {
                   5534:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5535:      to initial status i, ei. .
1.126     brouard  5536:   */
                   5537:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5538:   int nhstepma, nstepma; /* Decreasing with age */
                   5539:   double age, agelim, hf;
                   5540:   double ***p3matp, ***p3matm, ***varhe;
                   5541:   double **dnewm,**doldm;
                   5542:   double *xp, *xm;
                   5543:   double **gp, **gm;
                   5544:   double ***gradg, ***trgradg;
                   5545:   int theta;
                   5546: 
                   5547:   double eip, vip;
                   5548: 
                   5549:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5550:   xp=vector(1,npar);
                   5551:   xm=vector(1,npar);
                   5552:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5553:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5554:   
                   5555:   pstamp(ficresstdeij);
                   5556:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5557:   fprintf(ficresstdeij,"# Age");
                   5558:   for(i=1; i<=nlstate;i++){
                   5559:     for(j=1; j<=nlstate;j++)
                   5560:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5561:     fprintf(ficresstdeij," e%1d. ",i);
                   5562:   }
                   5563:   fprintf(ficresstdeij,"\n");
                   5564: 
                   5565:   pstamp(ficrescveij);
                   5566:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5567:   fprintf(ficrescveij,"# Age");
                   5568:   for(i=1; i<=nlstate;i++)
                   5569:     for(j=1; j<=nlstate;j++){
                   5570:       cptj= (j-1)*nlstate+i;
                   5571:       for(i2=1; i2<=nlstate;i2++)
                   5572:        for(j2=1; j2<=nlstate;j2++){
                   5573:          cptj2= (j2-1)*nlstate+i2;
                   5574:          if(cptj2 <= cptj)
                   5575:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5576:        }
                   5577:     }
                   5578:   fprintf(ficrescveij,"\n");
                   5579:   
                   5580:   if(estepm < stepm){
                   5581:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5582:   }
                   5583:   else  hstepm=estepm;   
                   5584:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5585:    * This is mainly to measure the difference between two models: for example
                   5586:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5587:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5588:    * progression in between and thus overestimating or underestimating according
                   5589:    * to the curvature of the survival function. If, for the same date, we 
                   5590:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5591:    * to compare the new estimate of Life expectancy with the same linear 
                   5592:    * hypothesis. A more precise result, taking into account a more precise
                   5593:    * curvature will be obtained if estepm is as small as stepm. */
                   5594: 
                   5595:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5596:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5597:      nhstepm is the number of hstepm from age to agelim 
                   5598:      nstepm is the number of stepm from age to agelin. 
                   5599:      Look at hpijx to understand the reason of that which relies in memory size
                   5600:      and note for a fixed period like estepm months */
                   5601:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5602:      survival function given by stepm (the optimization length). Unfortunately it
                   5603:      means that if the survival funtion is printed only each two years of age and if
                   5604:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5605:      results. So we changed our mind and took the option of the best precision.
                   5606:   */
                   5607:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5608: 
                   5609:   /* If stepm=6 months */
                   5610:   /* nhstepm age range expressed in number of stepm */
                   5611:   agelim=AGESUP;
                   5612:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5613:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5614:   /* if (stepm >= YEARM) hstepm=1;*/
                   5615:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5616:   
                   5617:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5618:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5619:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5620:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5621:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5622:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5623: 
                   5624:   for (age=bage; age<=fage; age ++){ 
                   5625:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5626:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5627:     /* if (stepm >= YEARM) hstepm=1;*/
                   5628:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5629:                
1.126     brouard  5630:     /* If stepm=6 months */
                   5631:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5632:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5633:     
                   5634:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5635:                
1.126     brouard  5636:     /* Computing  Variances of health expectancies */
                   5637:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5638:        decrease memory allocation */
                   5639:     for(theta=1; theta <=npar; theta++){
                   5640:       for(i=1; i<=npar; i++){ 
1.222     brouard  5641:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5642:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5643:       }
1.235     brouard  5644:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5645:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5646:                        
1.126     brouard  5647:       for(j=1; j<= nlstate; j++){
1.222     brouard  5648:        for(i=1; i<=nlstate; i++){
                   5649:          for(h=0; h<=nhstepm-1; h++){
                   5650:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5651:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5652:          }
                   5653:        }
1.126     brouard  5654:       }
1.218     brouard  5655:                        
1.126     brouard  5656:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5657:        for(h=0; h<=nhstepm-1; h++){
                   5658:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5659:        }
1.126     brouard  5660:     }/* End theta */
                   5661:     
                   5662:     
                   5663:     for(h=0; h<=nhstepm-1; h++)
                   5664:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5665:        for(theta=1; theta <=npar; theta++)
                   5666:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5667:     
1.218     brouard  5668:                
1.222     brouard  5669:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5670:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5671:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5672:                
1.222     brouard  5673:     printf("%d|",(int)age);fflush(stdout);
                   5674:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5675:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5676:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5677:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5678:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5679:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5680:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5681:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5682:       }
                   5683:     }
1.218     brouard  5684:                
1.126     brouard  5685:     /* Computing expectancies */
1.235     brouard  5686:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5687:     for(i=1; i<=nlstate;i++)
                   5688:       for(j=1; j<=nlstate;j++)
1.222     brouard  5689:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5690:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5691:                                        
1.222     brouard  5692:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5693:                                        
1.222     brouard  5694:        }
1.269   ! brouard  5695: 
        !          5696:     /* Standard deviation of expectancies ij */                
1.126     brouard  5697:     fprintf(ficresstdeij,"%3.0f",age );
                   5698:     for(i=1; i<=nlstate;i++){
                   5699:       eip=0.;
                   5700:       vip=0.;
                   5701:       for(j=1; j<=nlstate;j++){
1.222     brouard  5702:        eip += eij[i][j][(int)age];
                   5703:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5704:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5705:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5706:       }
                   5707:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5708:     }
                   5709:     fprintf(ficresstdeij,"\n");
1.218     brouard  5710:                
1.269   ! brouard  5711:     /* Variance of expectancies ij */          
1.126     brouard  5712:     fprintf(ficrescveij,"%3.0f",age );
                   5713:     for(i=1; i<=nlstate;i++)
                   5714:       for(j=1; j<=nlstate;j++){
1.222     brouard  5715:        cptj= (j-1)*nlstate+i;
                   5716:        for(i2=1; i2<=nlstate;i2++)
                   5717:          for(j2=1; j2<=nlstate;j2++){
                   5718:            cptj2= (j2-1)*nlstate+i2;
                   5719:            if(cptj2 <= cptj)
                   5720:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5721:          }
1.126     brouard  5722:       }
                   5723:     fprintf(ficrescveij,"\n");
1.218     brouard  5724:                
1.126     brouard  5725:   }
                   5726:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5727:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5728:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5729:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5730:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5731:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5732:   printf("\n");
                   5733:   fprintf(ficlog,"\n");
1.218     brouard  5734:        
1.126     brouard  5735:   free_vector(xm,1,npar);
                   5736:   free_vector(xp,1,npar);
                   5737:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5738:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5739:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5740: }
1.218     brouard  5741:  
1.126     brouard  5742: /************ Variance ******************/
1.235     brouard  5743:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5744:  {
                   5745:    /* Variance of health expectancies */
                   5746:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5747:    /* double **newm;*/
                   5748:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5749:   
                   5750:    /* int movingaverage(); */
                   5751:    double **dnewm,**doldm;
                   5752:    double **dnewmp,**doldmp;
                   5753:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5754:    int k;
                   5755:    double *xp;
                   5756:    double **gp, **gm;  /* for var eij */
                   5757:    double ***gradg, ***trgradg; /*for var eij */
                   5758:    double **gradgp, **trgradgp; /* for var p point j */
                   5759:    double *gpp, *gmp; /* for var p point j */
                   5760:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5761:    double ***p3mat;
                   5762:    double age,agelim, hf;
                   5763:    /* double ***mobaverage; */
                   5764:    int theta;
                   5765:    char digit[4];
                   5766:    char digitp[25];
                   5767: 
                   5768:    char fileresprobmorprev[FILENAMELENGTH];
                   5769: 
                   5770:    if(popbased==1){
                   5771:      if(mobilav!=0)
                   5772:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5773:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5774:    }
                   5775:    else 
                   5776:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5777: 
1.218     brouard  5778:    /* if (mobilav!=0) { */
                   5779:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5780:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5781:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5782:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5783:    /*   } */
                   5784:    /* } */
                   5785: 
                   5786:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5787:    sprintf(digit,"%-d",ij);
                   5788:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5789:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5790:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5791:    strcat(fileresprobmorprev,fileresu);
                   5792:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5793:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5794:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5795:    }
                   5796:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5797:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5798:    pstamp(ficresprobmorprev);
                   5799:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5800:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5801:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5802:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5803:    }
                   5804:    for(j=1;j<=cptcoveff;j++) 
                   5805:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5806:    fprintf(ficresprobmorprev,"\n");
                   5807: 
1.218     brouard  5808:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5809:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5810:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5811:      for(i=1; i<=nlstate;i++)
                   5812:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5813:    }  
                   5814:    fprintf(ficresprobmorprev,"\n");
                   5815:   
                   5816:    fprintf(ficgp,"\n# Routine varevsij");
                   5817:    fprintf(ficgp,"\nunset title \n");
                   5818:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5819:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5820:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5821:    /*   } */
                   5822:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5823:    pstamp(ficresvij);
                   5824:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5825:    if(popbased==1)
                   5826:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5827:    else
                   5828:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5829:    fprintf(ficresvij,"# Age");
                   5830:    for(i=1; i<=nlstate;i++)
                   5831:      for(j=1; j<=nlstate;j++)
                   5832:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5833:    fprintf(ficresvij,"\n");
                   5834: 
                   5835:    xp=vector(1,npar);
                   5836:    dnewm=matrix(1,nlstate,1,npar);
                   5837:    doldm=matrix(1,nlstate,1,nlstate);
                   5838:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5839:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5840: 
                   5841:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5842:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5843:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5844:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5845:   
1.218     brouard  5846:    if(estepm < stepm){
                   5847:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5848:    }
                   5849:    else  hstepm=estepm;   
                   5850:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5851:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5852:       nhstepm is the number of hstepm from age to agelim 
                   5853:       nstepm is the number of stepm from age to agelim. 
                   5854:       Look at function hpijx to understand why because of memory size limitations, 
                   5855:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5856:       survival function given by stepm (the optimization length). Unfortunately it
                   5857:       means that if the survival funtion is printed every two years of age and if
                   5858:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5859:       results. So we changed our mind and took the option of the best precision.
                   5860:    */
                   5861:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5862:    agelim = AGESUP;
                   5863:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5864:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5865:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5866:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5867:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5868:      gp=matrix(0,nhstepm,1,nlstate);
                   5869:      gm=matrix(0,nhstepm,1,nlstate);
                   5870:                
                   5871:                
                   5872:      for(theta=1; theta <=npar; theta++){
                   5873:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5874:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5875:        }
                   5876:                        
1.242     brouard  5877:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5878:                        
                   5879:        if (popbased==1) {
                   5880:         if(mobilav ==0){
                   5881:           for(i=1; i<=nlstate;i++)
                   5882:             prlim[i][i]=probs[(int)age][i][ij];
                   5883:         }else{ /* mobilav */ 
                   5884:           for(i=1; i<=nlstate;i++)
                   5885:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5886:         }
                   5887:        }
                   5888:                        
1.235     brouard  5889:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5890:        for(j=1; j<= nlstate; j++){
                   5891:         for(h=0; h<=nhstepm; h++){
                   5892:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5893:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5894:         }
                   5895:        }
                   5896:        /* Next for computing probability of death (h=1 means
                   5897:          computed over hstepm matrices product = hstepm*stepm months) 
                   5898:          as a weighted average of prlim.
                   5899:        */
                   5900:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5901:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5902:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5903:        }    
                   5904:        /* end probability of death */
                   5905:                        
                   5906:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5907:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5908:                        
1.242     brouard  5909:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5910:                        
                   5911:        if (popbased==1) {
                   5912:         if(mobilav ==0){
                   5913:           for(i=1; i<=nlstate;i++)
                   5914:             prlim[i][i]=probs[(int)age][i][ij];
                   5915:         }else{ /* mobilav */ 
                   5916:           for(i=1; i<=nlstate;i++)
                   5917:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5918:         }
                   5919:        }
                   5920:                        
1.235     brouard  5921:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5922:                        
                   5923:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5924:         for(h=0; h<=nhstepm; h++){
                   5925:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5926:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5927:         }
                   5928:        }
                   5929:        /* This for computing probability of death (h=1 means
                   5930:          computed over hstepm matrices product = hstepm*stepm months) 
                   5931:          as a weighted average of prlim.
                   5932:        */
                   5933:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5934:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5935:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5936:        }    
                   5937:        /* end probability of death */
                   5938:                        
                   5939:        for(j=1; j<= nlstate; j++) /* vareij */
                   5940:         for(h=0; h<=nhstepm; h++){
                   5941:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5942:         }
                   5943:                        
                   5944:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5945:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5946:        }
                   5947:                        
                   5948:      } /* End theta */
                   5949:                
                   5950:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5951:                
                   5952:      for(h=0; h<=nhstepm; h++) /* veij */
                   5953:        for(j=1; j<=nlstate;j++)
                   5954:         for(theta=1; theta <=npar; theta++)
                   5955:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5956:                
                   5957:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5958:        for(theta=1; theta <=npar; theta++)
                   5959:         trgradgp[j][theta]=gradgp[theta][j];
                   5960:                
                   5961:                
                   5962:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5963:      for(i=1;i<=nlstate;i++)
                   5964:        for(j=1;j<=nlstate;j++)
                   5965:         vareij[i][j][(int)age] =0.;
                   5966:                
                   5967:      for(h=0;h<=nhstepm;h++){
                   5968:        for(k=0;k<=nhstepm;k++){
                   5969:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5970:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5971:         for(i=1;i<=nlstate;i++)
                   5972:           for(j=1;j<=nlstate;j++)
                   5973:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5974:        }
                   5975:      }
                   5976:                
                   5977:      /* pptj */
                   5978:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5979:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5980:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5981:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5982:         varppt[j][i]=doldmp[j][i];
                   5983:      /* end ppptj */
                   5984:      /*  x centered again */
                   5985:                
1.242     brouard  5986:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5987:                
                   5988:      if (popbased==1) {
                   5989:        if(mobilav ==0){
                   5990:         for(i=1; i<=nlstate;i++)
                   5991:           prlim[i][i]=probs[(int)age][i][ij];
                   5992:        }else{ /* mobilav */ 
                   5993:         for(i=1; i<=nlstate;i++)
                   5994:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   5995:        }
                   5996:      }
                   5997:                
                   5998:      /* This for computing probability of death (h=1 means
                   5999:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6000:        as a weighted average of prlim.
                   6001:      */
1.235     brouard  6002:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6003:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6004:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6005:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6006:      }    
                   6007:      /* end probability of death */
                   6008:                
                   6009:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6010:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6011:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6012:        for(i=1; i<=nlstate;i++){
                   6013:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6014:        }
                   6015:      } 
                   6016:      fprintf(ficresprobmorprev,"\n");
                   6017:                
                   6018:      fprintf(ficresvij,"%.0f ",age );
                   6019:      for(i=1; i<=nlstate;i++)
                   6020:        for(j=1; j<=nlstate;j++){
                   6021:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6022:        }
                   6023:      fprintf(ficresvij,"\n");
                   6024:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6025:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6026:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6027:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6028:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6029:    } /* End age */
                   6030:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6031:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6032:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6033:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6034:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6035:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6036:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6037:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6038:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6039:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6040:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6041:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6042:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6043:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6044:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6045:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6046:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6047:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6048:     */
1.218     brouard  6049:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6050:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6051: 
1.218     brouard  6052:    free_vector(xp,1,npar);
                   6053:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6054:    free_matrix(dnewm,1,nlstate,1,npar);
                   6055:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6056:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6057:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6058:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6059:    fclose(ficresprobmorprev);
                   6060:    fflush(ficgp);
                   6061:    fflush(fichtm); 
                   6062:  }  /* end varevsij */
1.126     brouard  6063: 
                   6064: /************ Variance of prevlim ******************/
1.269   ! brouard  6065:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6066: {
1.205     brouard  6067:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6068:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6069: 
1.268     brouard  6070:   double **dnewmpar,**doldm;
1.126     brouard  6071:   int i, j, nhstepm, hstepm;
                   6072:   double *xp;
                   6073:   double *gp, *gm;
                   6074:   double **gradg, **trgradg;
1.208     brouard  6075:   double **mgm, **mgp;
1.126     brouard  6076:   double age,agelim;
                   6077:   int theta;
                   6078:   
                   6079:   pstamp(ficresvpl);
                   6080:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6081:   fprintf(ficresvpl,"# Age ");
                   6082:   if(nresult >=1)
                   6083:     fprintf(ficresvpl," Result# ");
1.126     brouard  6084:   for(i=1; i<=nlstate;i++)
                   6085:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6086:   fprintf(ficresvpl,"\n");
                   6087: 
                   6088:   xp=vector(1,npar);
1.268     brouard  6089:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6090:   doldm=matrix(1,nlstate,1,nlstate);
                   6091:   
                   6092:   hstepm=1*YEARM; /* Every year of age */
                   6093:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6094:   agelim = AGESUP;
                   6095:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6096:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6097:     if (stepm >= YEARM) hstepm=1;
                   6098:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6099:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6100:     mgp=matrix(1,npar,1,nlstate);
                   6101:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6102:     gp=vector(1,nlstate);
                   6103:     gm=vector(1,nlstate);
                   6104: 
                   6105:     for(theta=1; theta <=npar; theta++){
                   6106:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6107:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6108:       }
1.209     brouard  6109:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6110:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6111:       else
1.235     brouard  6112:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6113:       for(i=1;i<=nlstate;i++){
1.126     brouard  6114:        gp[i] = prlim[i][i];
1.208     brouard  6115:        mgp[theta][i] = prlim[i][i];
                   6116:       }
1.126     brouard  6117:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6118:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6119:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6120:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6121:       else
1.235     brouard  6122:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6123:       for(i=1;i<=nlstate;i++){
1.126     brouard  6124:        gm[i] = prlim[i][i];
1.208     brouard  6125:        mgm[theta][i] = prlim[i][i];
                   6126:       }
1.126     brouard  6127:       for(i=1;i<=nlstate;i++)
                   6128:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6129:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6130:     } /* End theta */
                   6131: 
                   6132:     trgradg =matrix(1,nlstate,1,npar);
                   6133: 
                   6134:     for(j=1; j<=nlstate;j++)
                   6135:       for(theta=1; theta <=npar; theta++)
                   6136:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6137:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6138:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6139:     /*   for(j=1; j<=nlstate;j++){ */
                   6140:     /*         printf(" %d ",j); */
                   6141:     /*         for(theta=1; theta <=npar; theta++) */
                   6142:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6143:     /*         printf("\n "); */
                   6144:     /*   } */
                   6145:     /* } */
                   6146:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6147:     /*   printf("\n gradg %d ",(int)age); */
                   6148:     /*   for(j=1; j<=nlstate;j++){ */
                   6149:     /*         printf("%d ",j); */
                   6150:     /*         for(theta=1; theta <=npar; theta++) */
                   6151:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6152:     /*         printf("\n "); */
                   6153:     /*   } */
                   6154:     /* } */
1.126     brouard  6155: 
                   6156:     for(i=1;i<=nlstate;i++)
                   6157:       varpl[i][(int)age] =0.;
1.209     brouard  6158:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6159:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6160:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6161:     }else{
1.268     brouard  6162:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6163:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6164:     }
1.126     brouard  6165:     for(i=1;i<=nlstate;i++)
                   6166:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6167: 
                   6168:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6169:     if(nresult >=1)
                   6170:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6171:     for(i=1; i<=nlstate;i++)
                   6172:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6173:     fprintf(ficresvpl,"\n");
                   6174:     free_vector(gp,1,nlstate);
                   6175:     free_vector(gm,1,nlstate);
1.208     brouard  6176:     free_matrix(mgm,1,npar,1,nlstate);
                   6177:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6178:     free_matrix(gradg,1,npar,1,nlstate);
                   6179:     free_matrix(trgradg,1,nlstate,1,npar);
                   6180:   } /* End age */
                   6181: 
                   6182:   free_vector(xp,1,npar);
                   6183:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6184:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6185: 
                   6186: }
                   6187: 
                   6188: 
                   6189: /************ Variance of backprevalence limit ******************/
1.269   ! brouard  6190:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6191: {
                   6192:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6193:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6194: 
                   6195:   double **dnewmpar,**doldm;
                   6196:   int i, j, nhstepm, hstepm;
                   6197:   double *xp;
                   6198:   double *gp, *gm;
                   6199:   double **gradg, **trgradg;
                   6200:   double **mgm, **mgp;
                   6201:   double age,agelim;
                   6202:   int theta;
                   6203:   
                   6204:   pstamp(ficresvbl);
                   6205:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6206:   fprintf(ficresvbl,"# Age ");
                   6207:   if(nresult >=1)
                   6208:     fprintf(ficresvbl," Result# ");
                   6209:   for(i=1; i<=nlstate;i++)
                   6210:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6211:   fprintf(ficresvbl,"\n");
                   6212: 
                   6213:   xp=vector(1,npar);
                   6214:   dnewmpar=matrix(1,nlstate,1,npar);
                   6215:   doldm=matrix(1,nlstate,1,nlstate);
                   6216:   
                   6217:   hstepm=1*YEARM; /* Every year of age */
                   6218:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6219:   agelim = AGEINF;
                   6220:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6221:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6222:     if (stepm >= YEARM) hstepm=1;
                   6223:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6224:     gradg=matrix(1,npar,1,nlstate);
                   6225:     mgp=matrix(1,npar,1,nlstate);
                   6226:     mgm=matrix(1,npar,1,nlstate);
                   6227:     gp=vector(1,nlstate);
                   6228:     gm=vector(1,nlstate);
                   6229: 
                   6230:     for(theta=1; theta <=npar; theta++){
                   6231:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6232:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6233:       }
                   6234:       if(mobilavproj > 0 )
                   6235:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6236:       else
                   6237:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6238:       for(i=1;i<=nlstate;i++){
                   6239:        gp[i] = bprlim[i][i];
                   6240:        mgp[theta][i] = bprlim[i][i];
                   6241:       }
                   6242:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6243:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6244:        if(mobilavproj > 0 )
                   6245:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6246:        else
                   6247:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6248:       for(i=1;i<=nlstate;i++){
                   6249:        gm[i] = bprlim[i][i];
                   6250:        mgm[theta][i] = bprlim[i][i];
                   6251:       }
                   6252:       for(i=1;i<=nlstate;i++)
                   6253:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6254:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6255:     } /* End theta */
                   6256: 
                   6257:     trgradg =matrix(1,nlstate,1,npar);
                   6258: 
                   6259:     for(j=1; j<=nlstate;j++)
                   6260:       for(theta=1; theta <=npar; theta++)
                   6261:        trgradg[j][theta]=gradg[theta][j];
                   6262:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6263:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6264:     /*   for(j=1; j<=nlstate;j++){ */
                   6265:     /*         printf(" %d ",j); */
                   6266:     /*         for(theta=1; theta <=npar; theta++) */
                   6267:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6268:     /*         printf("\n "); */
                   6269:     /*   } */
                   6270:     /* } */
                   6271:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6272:     /*   printf("\n gradg %d ",(int)age); */
                   6273:     /*   for(j=1; j<=nlstate;j++){ */
                   6274:     /*         printf("%d ",j); */
                   6275:     /*         for(theta=1; theta <=npar; theta++) */
                   6276:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6277:     /*         printf("\n "); */
                   6278:     /*   } */
                   6279:     /* } */
                   6280: 
                   6281:     for(i=1;i<=nlstate;i++)
                   6282:       varbpl[i][(int)age] =0.;
                   6283:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6284:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6285:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6286:     }else{
                   6287:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6288:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6289:     }
                   6290:     for(i=1;i<=nlstate;i++)
                   6291:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6292: 
                   6293:     fprintf(ficresvbl,"%.0f ",age );
                   6294:     if(nresult >=1)
                   6295:       fprintf(ficresvbl,"%d ",nres );
                   6296:     for(i=1; i<=nlstate;i++)
                   6297:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6298:     fprintf(ficresvbl,"\n");
                   6299:     free_vector(gp,1,nlstate);
                   6300:     free_vector(gm,1,nlstate);
                   6301:     free_matrix(mgm,1,npar,1,nlstate);
                   6302:     free_matrix(mgp,1,npar,1,nlstate);
                   6303:     free_matrix(gradg,1,npar,1,nlstate);
                   6304:     free_matrix(trgradg,1,nlstate,1,npar);
                   6305:   } /* End age */
                   6306: 
                   6307:   free_vector(xp,1,npar);
                   6308:   free_matrix(doldm,1,nlstate,1,npar);
                   6309:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6310: 
                   6311: }
                   6312: 
                   6313: /************ Variance of one-step probabilities  ******************/
                   6314: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6315:  {
                   6316:    int i, j=0,  k1, l1, tj;
                   6317:    int k2, l2, j1,  z1;
                   6318:    int k=0, l;
                   6319:    int first=1, first1, first2;
                   6320:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6321:    double **dnewm,**doldm;
                   6322:    double *xp;
                   6323:    double *gp, *gm;
                   6324:    double **gradg, **trgradg;
                   6325:    double **mu;
                   6326:    double age, cov[NCOVMAX+1];
                   6327:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6328:    int theta;
                   6329:    char fileresprob[FILENAMELENGTH];
                   6330:    char fileresprobcov[FILENAMELENGTH];
                   6331:    char fileresprobcor[FILENAMELENGTH];
                   6332:    double ***varpij;
                   6333: 
                   6334:    strcpy(fileresprob,"PROB_"); 
                   6335:    strcat(fileresprob,fileres);
                   6336:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6337:      printf("Problem with resultfile: %s\n", fileresprob);
                   6338:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6339:    }
                   6340:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6341:    strcat(fileresprobcov,fileresu);
                   6342:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6343:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6344:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6345:    }
                   6346:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6347:    strcat(fileresprobcor,fileresu);
                   6348:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6349:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6350:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6351:    }
                   6352:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6353:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6354:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6355:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6356:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6357:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6358:    pstamp(ficresprob);
                   6359:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6360:    fprintf(ficresprob,"# Age");
                   6361:    pstamp(ficresprobcov);
                   6362:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6363:    fprintf(ficresprobcov,"# Age");
                   6364:    pstamp(ficresprobcor);
                   6365:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6366:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6367: 
                   6368: 
1.222     brouard  6369:    for(i=1; i<=nlstate;i++)
                   6370:      for(j=1; j<=(nlstate+ndeath);j++){
                   6371:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6372:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6373:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6374:      }  
                   6375:    /* fprintf(ficresprob,"\n");
                   6376:       fprintf(ficresprobcov,"\n");
                   6377:       fprintf(ficresprobcor,"\n");
                   6378:    */
                   6379:    xp=vector(1,npar);
                   6380:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6381:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6382:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6383:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6384:    first=1;
                   6385:    fprintf(ficgp,"\n# Routine varprob");
                   6386:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6387:    fprintf(fichtm,"\n");
                   6388: 
1.266     brouard  6389:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6390:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6391:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6392: and drawn. It helps understanding how is the covariance between two incidences.\
                   6393:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6394:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6395: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6396: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6397: standard deviations wide on each axis. <br>\
                   6398:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6399:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6400: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6401: 
1.222     brouard  6402:    cov[1]=1;
                   6403:    /* tj=cptcoveff; */
1.225     brouard  6404:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6405:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6406:    j1=0;
1.224     brouard  6407:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6408:      if  (cptcovn>0) {
                   6409:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6410:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6411:        fprintf(ficresprob, "**********\n#\n");
                   6412:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6413:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6414:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6415:                        
1.222     brouard  6416:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6417:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6418:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6419:                        
                   6420:                        
1.222     brouard  6421:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6422:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6423:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6424:                        
1.222     brouard  6425:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6426:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6427:        fprintf(ficresprobcor, "**********\n#");    
                   6428:        if(invalidvarcomb[j1]){
                   6429:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6430:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6431:         continue;
                   6432:        }
                   6433:      }
                   6434:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6435:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6436:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6437:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6438:      for (age=bage; age<=fage; age ++){ 
                   6439:        cov[2]=age;
                   6440:        if(nagesqr==1)
                   6441:         cov[3]= age*age;
                   6442:        for (k=1; k<=cptcovn;k++) {
                   6443:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6444:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6445:                                                                    * 1  1 1 1 1
                   6446:                                                                    * 2  2 1 1 1
                   6447:                                                                    * 3  1 2 1 1
                   6448:                                                                    */
                   6449:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6450:        }
                   6451:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6452:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6453:        for (k=1; k<=cptcovprod;k++)
                   6454:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6455:                        
                   6456:                        
1.222     brouard  6457:        for(theta=1; theta <=npar; theta++){
                   6458:         for(i=1; i<=npar; i++)
                   6459:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6460:                                
1.222     brouard  6461:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6462:                                
1.222     brouard  6463:         k=0;
                   6464:         for(i=1; i<= (nlstate); i++){
                   6465:           for(j=1; j<=(nlstate+ndeath);j++){
                   6466:             k=k+1;
                   6467:             gp[k]=pmmij[i][j];
                   6468:           }
                   6469:         }
1.220     brouard  6470:                                
1.222     brouard  6471:         for(i=1; i<=npar; i++)
                   6472:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6473:                                
1.222     brouard  6474:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6475:         k=0;
                   6476:         for(i=1; i<=(nlstate); i++){
                   6477:           for(j=1; j<=(nlstate+ndeath);j++){
                   6478:             k=k+1;
                   6479:             gm[k]=pmmij[i][j];
                   6480:           }
                   6481:         }
1.220     brouard  6482:                                
1.222     brouard  6483:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6484:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6485:        }
1.126     brouard  6486: 
1.222     brouard  6487:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6488:         for(theta=1; theta <=npar; theta++)
                   6489:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6490:                        
1.222     brouard  6491:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6492:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6493:                        
1.222     brouard  6494:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6495:                        
1.222     brouard  6496:        k=0;
                   6497:        for(i=1; i<=(nlstate); i++){
                   6498:         for(j=1; j<=(nlstate+ndeath);j++){
                   6499:           k=k+1;
                   6500:           mu[k][(int) age]=pmmij[i][j];
                   6501:         }
                   6502:        }
                   6503:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6504:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6505:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6506:                        
1.222     brouard  6507:        /*printf("\n%d ",(int)age);
                   6508:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6509:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6510:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6511:         }*/
1.220     brouard  6512:                        
1.222     brouard  6513:        fprintf(ficresprob,"\n%d ",(int)age);
                   6514:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6515:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6516:                        
1.222     brouard  6517:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6518:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6519:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6520:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6521:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6522:        }
                   6523:        i=0;
                   6524:        for (k=1; k<=(nlstate);k++){
                   6525:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6526:           i++;
                   6527:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6528:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6529:           for (j=1; j<=i;j++){
                   6530:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6531:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6532:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6533:           }
                   6534:         }
                   6535:        }/* end of loop for state */
                   6536:      } /* end of loop for age */
                   6537:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6538:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6539:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6540:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6541:     
                   6542:      /* Confidence intervalle of pij  */
                   6543:      /*
                   6544:        fprintf(ficgp,"\nunset parametric;unset label");
                   6545:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6546:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6547:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6548:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6549:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6550:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6551:      */
                   6552:                
                   6553:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6554:      first1=1;first2=2;
                   6555:      for (k2=1; k2<=(nlstate);k2++){
                   6556:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6557:         if(l2==k2) continue;
                   6558:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6559:         for (k1=1; k1<=(nlstate);k1++){
                   6560:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6561:             if(l1==k1) continue;
                   6562:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6563:             if(i<=j) continue;
                   6564:             for (age=bage; age<=fage; age ++){ 
                   6565:               if ((int)age %5==0){
                   6566:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6567:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6568:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6569:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6570:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6571:                 c12=cv12/sqrt(v1*v2);
                   6572:                 /* Computing eigen value of matrix of covariance */
                   6573:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6574:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6575:                 if ((lc2 <0) || (lc1 <0) ){
                   6576:                   if(first2==1){
                   6577:                     first1=0;
                   6578:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6579:                   }
                   6580:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6581:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6582:                   /* lc2=fabs(lc2); */
                   6583:                 }
1.220     brouard  6584:                                                                
1.222     brouard  6585:                 /* Eigen vectors */
                   6586:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6587:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6588:                 v21=(lc1-v1)/cv12*v11;
                   6589:                 v12=-v21;
                   6590:                 v22=v11;
                   6591:                 tnalp=v21/v11;
                   6592:                 if(first1==1){
                   6593:                   first1=0;
                   6594:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6595:                 }
                   6596:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6597:                 /*printf(fignu*/
                   6598:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6599:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6600:                 if(first==1){
                   6601:                   first=0;
                   6602:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6603:                   fprintf(ficgp,"\nset parametric;unset label");
                   6604:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6605:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6606:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6607:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6608: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6609:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6610:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6611:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6612:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6613:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6614:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6615:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6616:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.266     brouard  6617:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6618:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6619:                 }else{
                   6620:                   first=0;
                   6621:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6622:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6623:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6624:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6625:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6626:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6627:                 }/* if first */
                   6628:               } /* age mod 5 */
                   6629:             } /* end loop age */
                   6630:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6631:             first=1;
                   6632:           } /*l12 */
                   6633:         } /* k12 */
                   6634:        } /*l1 */
                   6635:      }/* k1 */
                   6636:    }  /* loop on combination of covariates j1 */
                   6637:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6638:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6639:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6640:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6641:    free_vector(xp,1,npar);
                   6642:    fclose(ficresprob);
                   6643:    fclose(ficresprobcov);
                   6644:    fclose(ficresprobcor);
                   6645:    fflush(ficgp);
                   6646:    fflush(fichtmcov);
                   6647:  }
1.126     brouard  6648: 
                   6649: 
                   6650: /******************* Printing html file ***********/
1.201     brouard  6651: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6652:                  int lastpass, int stepm, int weightopt, char model[],\
                   6653:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6654:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.213     brouard  6655:                  double jprev1, double mprev1,double anprev1, double dateprev1, \
                   6656:                  double jprev2, double mprev2,double anprev2, double dateprev2){
1.237     brouard  6657:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6658: 
                   6659:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6660:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6661: </ul>");
1.237     brouard  6662:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6663: </ul>", model);
1.214     brouard  6664:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6665:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6666:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6667:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6668:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6669:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6670:    fprintf(fichtm,"\
                   6671:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6672:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6673:    fprintf(fichtm,"\
1.217     brouard  6674:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6675:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6676:    fprintf(fichtm,"\
1.126     brouard  6677:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6678:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6679:    fprintf(fichtm,"\
1.217     brouard  6680:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6681:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6682:    fprintf(fichtm,"\
1.211     brouard  6683:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6684:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6685:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6686:    if(prevfcast==1){
                   6687:      fprintf(fichtm,"\
                   6688:  - Prevalence projections by age and states:                           \
1.201     brouard  6689:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6690:    }
1.126     brouard  6691: 
                   6692: 
1.225     brouard  6693:    m=pow(2,cptcoveff);
1.222     brouard  6694:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6695: 
1.264     brouard  6696:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6697: 
                   6698:    jj1=0;
                   6699: 
                   6700:    fprintf(fichtm," \n<ul>");
                   6701:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6702:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6703:      if(m != 1 && TKresult[nres]!= k1)
                   6704:        continue;
                   6705:      jj1++;
                   6706:      if (cptcovn > 0) {
                   6707:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6708:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6709:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6710:        }
                   6711:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6712:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6713:        }
                   6714:        fprintf(fichtm,"\">");
                   6715:        
                   6716:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6717:        fprintf(fichtm,"************ Results for covariates");
                   6718:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6719:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6720:        }
                   6721:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6722:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6723:        }
                   6724:        if(invalidvarcomb[k1]){
                   6725:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6726:         continue;
                   6727:        }
                   6728:        fprintf(fichtm,"</a></li>");
                   6729:      } /* cptcovn >0 */
                   6730:    }
                   6731:      fprintf(fichtm," \n</ul>");
                   6732: 
1.222     brouard  6733:    jj1=0;
1.237     brouard  6734: 
                   6735:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6736:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6737:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6738:        continue;
1.220     brouard  6739: 
1.222     brouard  6740:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6741:      jj1++;
                   6742:      if (cptcovn > 0) {
1.264     brouard  6743:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6744:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6745:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6746:        }
                   6747:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6748:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6749:        }
                   6750:        fprintf(fichtm,"\"</a>");
                   6751:  
1.222     brouard  6752:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6753:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6754:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6755:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6756:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6757:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6758:        }
1.237     brouard  6759:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6760:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6761:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6762:       }
                   6763:        
1.230     brouard  6764:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6765:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6766:        if(invalidvarcomb[k1]){
                   6767:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6768:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6769:         continue;
                   6770:        }
                   6771:      }
                   6772:      /* aij, bij */
1.259     brouard  6773:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6774: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6775:      /* Pij */
1.241     brouard  6776:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6777: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6778:      /* Quasi-incidences */
                   6779:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6780:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6781:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6782: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6783: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6784:      /* Survival functions (period) in state j */
                   6785:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6786:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6787: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6788:      }
                   6789:      /* State specific survival functions (period) */
                   6790:      for(cpt=1; cpt<=nlstate;cpt++){
                   6791:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6792:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6793:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6794:      }
                   6795:      /* Period (stable) prevalence in each health state */
                   6796:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6797:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6798: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6799:      }
                   6800:      if(backcast==1){
                   6801:        /* Period (stable) back prevalence in each health state */
                   6802:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6803:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6804: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6805:        }
1.217     brouard  6806:      }
1.222     brouard  6807:      if(prevfcast==1){
                   6808:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6809:        for(cpt=1; cpt<=nlstate;cpt++){
1.268     brouard  6810:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.258     brouard  6811: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6812:        }
                   6813:      }
1.268     brouard  6814:      if(backcast==1){
                   6815:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6816:        for(cpt=1; cpt<=nlstate;cpt++){
                   6817:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d) up to stable (mixed) back prevalence in state %d. Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) with weights corresponding to observed prevalence  at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6818: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   6819:        }
                   6820:      }
1.220     brouard  6821:         
1.222     brouard  6822:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6823:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6824: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6825:      }
                   6826:      /* } /\* end i1 *\/ */
                   6827:    }/* End k1 */
                   6828:    fprintf(fichtm,"</ul>");
1.126     brouard  6829: 
1.222     brouard  6830:    fprintf(fichtm,"\
1.126     brouard  6831: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6832:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6833:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6834: But because parameters are usually highly correlated (a higher incidence of disability \
                   6835: and a higher incidence of recovery can give very close observed transition) it might \
                   6836: be very useful to look not only at linear confidence intervals estimated from the \
                   6837: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6838: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6839: covariance matrix of the one-step probabilities. \
                   6840: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6841: 
1.222     brouard  6842:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6843:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6844:    fprintf(fichtm,"\
1.126     brouard  6845:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6846:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6847: 
1.222     brouard  6848:    fprintf(fichtm,"\
1.126     brouard  6849:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6850:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6851:    fprintf(fichtm,"\
1.126     brouard  6852:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6853:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6854:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6855:    fprintf(fichtm,"\
1.126     brouard  6856:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6857:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6858:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6859:    fprintf(fichtm,"\
1.128     brouard  6860:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6861:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6862:    fprintf(fichtm,"\
1.128     brouard  6863:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6864:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6865:    fprintf(fichtm,"\
1.126     brouard  6866:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6867:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6868: 
                   6869: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6870: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6871: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6872: /*     <br>",fileres,fileres,fileres,fileres); */
                   6873: /*  else  */
                   6874: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6875:    fflush(fichtm);
                   6876:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6877: 
1.225     brouard  6878:    m=pow(2,cptcoveff);
1.222     brouard  6879:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6880: 
1.222     brouard  6881:    jj1=0;
1.237     brouard  6882: 
1.241     brouard  6883:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6884:    for(k1=1; k1<=m;k1++){
1.253     brouard  6885:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6886:        continue;
1.222     brouard  6887:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6888:      jj1++;
1.126     brouard  6889:      if (cptcovn > 0) {
                   6890:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6891:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6892:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6893:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6894:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6895:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6896:       }
                   6897: 
1.126     brouard  6898:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6899: 
1.222     brouard  6900:        if(invalidvarcomb[k1]){
                   6901:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6902:         continue;
                   6903:        }
1.126     brouard  6904:      }
                   6905:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6906:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6907: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6908: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6909:      }
                   6910:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6911: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6912: true period expectancies (those weighted with period prevalences are also\
                   6913:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6914:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6915: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6916:      /* } /\* end i1 *\/ */
                   6917:    }/* End k1 */
1.241     brouard  6918:   }/* End nres */
1.222     brouard  6919:    fprintf(fichtm,"</ul>");
                   6920:    fflush(fichtm);
1.126     brouard  6921: }
                   6922: 
                   6923: /******************* Gnuplot file **************/
1.268     brouard  6924: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  6925: 
                   6926:   char dirfileres[132],optfileres[132];
1.264     brouard  6927:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  6928:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6929:   int lv=0, vlv=0, kl=0;
1.130     brouard  6930:   int ng=0;
1.201     brouard  6931:   int vpopbased;
1.223     brouard  6932:   int ioffset; /* variable offset for columns */
1.235     brouard  6933:   int nres=0; /* Index of resultline */
1.266     brouard  6934:   int istart=1; /* For starting graphs in projections */
1.219     brouard  6935: 
1.126     brouard  6936: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6937: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6938: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6939: /*   } */
                   6940: 
                   6941:   /*#ifdef windows */
                   6942:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6943:   /*#endif */
1.225     brouard  6944:   m=pow(2,cptcoveff);
1.126     brouard  6945: 
1.202     brouard  6946:   /* Contribution to likelihood */
                   6947:   /* Plot the probability implied in the likelihood */
1.223     brouard  6948:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6949:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6950:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6951:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6952: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6953:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6954: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6955:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6956:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6957:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6958:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6959:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6960:   for (i=1; i<= nlstate ; i ++) {
                   6961:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6962:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6963:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6964:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6965:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6966:     }
                   6967:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6968:   }
                   6969:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6970:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6971:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6972:   fprintf(ficgp,"\nset out;unset log\n");
                   6973:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6974: 
1.126     brouard  6975:   strcpy(dirfileres,optionfilefiname);
                   6976:   strcpy(optfileres,"vpl");
1.223     brouard  6977:   /* 1eme*/
1.238     brouard  6978:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6979:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6980:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6981:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6982:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  6983:          continue;
                   6984:        /* We are interested in selected combination by the resultline */
1.246     brouard  6985:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  6986:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  6987:        strcpy(gplotlabel,"(");
1.238     brouard  6988:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   6989:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   6990:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   6991:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   6992:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   6993:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   6994:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  6995:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  6996:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  6997:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  6998:        }
                   6999:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7000:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7001:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7002:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7003:        }
                   7004:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7005:        /* printf("\n#\n"); */
1.238     brouard  7006:        fprintf(ficgp,"\n#\n");
                   7007:        if(invalidvarcomb[k1]){
1.260     brouard  7008:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7009:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7010:          continue;
                   7011:        }
1.235     brouard  7012:       
1.241     brouard  7013:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7014:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.264     brouard  7015:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7016:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7017:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7018:       /* k1-1 error should be nres-1*/
1.238     brouard  7019:        for (i=1; i<= nlstate ; i ++) {
                   7020:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7021:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7022:        }
1.260     brouard  7023:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7024:        for (i=1; i<= nlstate ; i ++) {
                   7025:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7026:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7027:        } 
1.260     brouard  7028:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7029:        for (i=1; i<= nlstate ; i ++) {
                   7030:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7031:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7032:        }  
1.265     brouard  7033:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7034:        
                   7035:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7036:         if(cptcoveff ==0){
                   7037:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+(cpt-1),  cpt );
                   7038:        }else{
                   7039:          kl=0;
                   7040:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7041:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7042:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7043:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7044:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7045:            vlv= nbcode[Tvaraff[k]][lv];
                   7046:            kl++;
                   7047:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7048:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7049:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7050:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7051:            if(k==cptcoveff){
                   7052:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7053:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7054:            }else{
                   7055:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7056:              kl++;
                   7057:            }
                   7058:          } /* end covariate */
                   7059:        } /* end if no covariate */
                   7060: 
1.238     brouard  7061:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7062:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7063:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7064:          if(cptcoveff ==0){
1.245     brouard  7065:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7066:          }else{
                   7067:            kl=0;
                   7068:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7069:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7070:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7071:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7072:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7073:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7074:              kl++;
1.238     brouard  7075:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7076:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7077:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7078:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7079:              if(k==cptcoveff){
1.245     brouard  7080:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7081:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7082:              }else{
                   7083:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7084:                kl++;
                   7085:              }
                   7086:            } /* end covariate */
                   7087:          } /* end if no covariate */
1.268     brouard  7088:          if(backcast == 1){
                   7089:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7090:            /* k1-1 error should be nres-1*/
                   7091:            for (i=1; i<= nlstate ; i ++) {
                   7092:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7093:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7094:            }
                   7095:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7096:            for (i=1; i<= nlstate ; i ++) {
                   7097:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7098:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7099:            } 
                   7100:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
                   7101:            for (i=1; i<= nlstate ; i ++) {
                   7102:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7103:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7104:            } 
                   7105:            fprintf(ficgp,"\" t\"\" w l lt 1");
                   7106:          } /* end if backprojcast */
1.238     brouard  7107:        } /* end if backcast */
1.264     brouard  7108:        fprintf(ficgp,"\nset out ;unset label;\n");
1.238     brouard  7109:       } /* nres */
1.201     brouard  7110:     } /* k1 */
                   7111:   } /* cpt */
1.235     brouard  7112: 
                   7113:   
1.126     brouard  7114:   /*2 eme*/
1.238     brouard  7115:   for (k1=1; k1<= m ; k1 ++){  
                   7116:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7117:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7118:        continue;
                   7119:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7120:       strcpy(gplotlabel,"(");
1.238     brouard  7121:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7122:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7123:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7124:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7125:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7126:        vlv= nbcode[Tvaraff[k]][lv];
                   7127:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7128:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7129:       }
1.237     brouard  7130:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7131:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7132:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7133:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7134:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7135:       }
1.264     brouard  7136:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7137:       fprintf(ficgp,"\n#\n");
1.223     brouard  7138:       if(invalidvarcomb[k1]){
                   7139:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7140:        continue;
                   7141:       }
1.219     brouard  7142:                        
1.241     brouard  7143:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7144:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7145:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7146:        if(vpopbased==0){
1.238     brouard  7147:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7148:        }else
1.238     brouard  7149:          fprintf(ficgp,"\nreplot ");
                   7150:        for (i=1; i<= nlstate+1 ; i ++) {
                   7151:          k=2*i;
1.261     brouard  7152:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7153:          for (j=1; j<= nlstate+1 ; j ++) {
                   7154:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7155:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7156:          }   
                   7157:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7158:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7159:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7160:          for (j=1; j<= nlstate+1 ; j ++) {
                   7161:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7162:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7163:          }   
                   7164:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7165:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7166:          for (j=1; j<= nlstate+1 ; j ++) {
                   7167:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7168:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7169:          }   
                   7170:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7171:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7172:        } /* state */
                   7173:       } /* vpopbased */
1.264     brouard  7174:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7175:     } /* end nres */
                   7176:   } /* k1 end 2 eme*/
                   7177:        
                   7178:        
                   7179:   /*3eme*/
                   7180:   for (k1=1; k1<= m ; k1 ++){
                   7181:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7182:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7183:        continue;
                   7184: 
                   7185:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7186:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7187:        strcpy(gplotlabel,"(");
1.238     brouard  7188:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7189:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7190:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7191:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7192:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7193:          vlv= nbcode[Tvaraff[k]][lv];
                   7194:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7195:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7196:        }
                   7197:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7198:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7199:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7200:        }       
1.264     brouard  7201:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7202:        fprintf(ficgp,"\n#\n");
                   7203:        if(invalidvarcomb[k1]){
                   7204:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7205:          continue;
                   7206:        }
                   7207:                        
                   7208:        /*       k=2+nlstate*(2*cpt-2); */
                   7209:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7210:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7211:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7212:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7213: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7214:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7215:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7216:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7217:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7218:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7219:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7220:                                
1.238     brouard  7221:        */
                   7222:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7223:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7224:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7225:                                
1.238     brouard  7226:        } 
1.261     brouard  7227:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7228:       }
1.264     brouard  7229:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7230:     } /* end nres */
                   7231:   } /* end kl 3eme */
1.126     brouard  7232:   
1.223     brouard  7233:   /* 4eme */
1.201     brouard  7234:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7235:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7236:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7237:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7238:        continue;
1.238     brouard  7239:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7240:        strcpy(gplotlabel,"(");
1.238     brouard  7241:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7242:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7243:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7244:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7245:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7246:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7247:          vlv= nbcode[Tvaraff[k]][lv];
                   7248:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7249:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7250:        }
                   7251:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7252:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7253:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7254:        }       
1.264     brouard  7255:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7256:        fprintf(ficgp,"\n#\n");
                   7257:        if(invalidvarcomb[k1]){
                   7258:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7259:          continue;
1.223     brouard  7260:        }
1.238     brouard  7261:       
1.241     brouard  7262:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7263:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7264:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7265: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7266:        k=3;
                   7267:        for (i=1; i<= nlstate ; i ++){
                   7268:          if(i==1){
                   7269:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7270:          }else{
                   7271:            fprintf(ficgp,", '' ");
                   7272:          }
                   7273:          l=(nlstate+ndeath)*(i-1)+1;
                   7274:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7275:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7276:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7277:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7278:        } /* nlstate */
1.264     brouard  7279:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7280:       } /* end cpt state*/ 
                   7281:     } /* end nres */
                   7282:   } /* end covariate k1 */  
                   7283: 
1.220     brouard  7284: /* 5eme */
1.201     brouard  7285:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7286:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7287:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7288:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7289:        continue;
1.238     brouard  7290:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7291:        strcpy(gplotlabel,"(");
1.238     brouard  7292:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7293:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7294:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7295:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7296:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7297:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7298:          vlv= nbcode[Tvaraff[k]][lv];
                   7299:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7300:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7301:        }
                   7302:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7303:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7304:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7305:        }       
1.264     brouard  7306:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7307:        fprintf(ficgp,"\n#\n");
                   7308:        if(invalidvarcomb[k1]){
                   7309:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7310:          continue;
                   7311:        }
1.227     brouard  7312:       
1.241     brouard  7313:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7314:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7315:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7316: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7317:        k=3;
                   7318:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7319:          if(j==1)
                   7320:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7321:          else
                   7322:            fprintf(ficgp,", '' ");
                   7323:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7324:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7325:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7326:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7327:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7328:        } /* nlstate */
                   7329:        fprintf(ficgp,", '' ");
                   7330:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7331:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7332:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7333:          if(j < nlstate)
                   7334:            fprintf(ficgp,"$%d +",k+l);
                   7335:          else
                   7336:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7337:        }
1.264     brouard  7338:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7339:       } /* end cpt state*/ 
                   7340:     } /* end covariate */  
                   7341:   } /* end nres */
1.227     brouard  7342:   
1.220     brouard  7343: /* 6eme */
1.202     brouard  7344:   /* CV preval stable (period) for each covariate */
1.237     brouard  7345:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7346:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7347:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7348:       continue;
1.255     brouard  7349:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7350:       strcpy(gplotlabel,"(");      
1.211     brouard  7351:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7352:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7353:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7354:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7355:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7356:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7357:        vlv= nbcode[Tvaraff[k]][lv];
                   7358:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7359:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7360:       }
1.237     brouard  7361:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7362:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7363:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7364:       }        
1.264     brouard  7365:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7366:       fprintf(ficgp,"\n#\n");
1.223     brouard  7367:       if(invalidvarcomb[k1]){
1.227     brouard  7368:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7369:        continue;
1.223     brouard  7370:       }
1.227     brouard  7371:       
1.241     brouard  7372:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7373:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7374:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7375: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7376:       k=3; /* Offset */
1.255     brouard  7377:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7378:        if(i==1)
                   7379:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7380:        else
                   7381:          fprintf(ficgp,", '' ");
1.255     brouard  7382:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7383:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7384:        for (j=2; j<= nlstate ; j ++)
                   7385:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7386:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7387:       } /* nlstate */
1.264     brouard  7388:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7389:     } /* end cpt state*/ 
                   7390:   } /* end covariate */  
1.227     brouard  7391:   
                   7392:   
1.220     brouard  7393: /* 7eme */
1.218     brouard  7394:   if(backcast == 1){
1.217     brouard  7395:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7396:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7397:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7398:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7399:        continue;
1.268     brouard  7400:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7401:        strcpy(gplotlabel,"(");      
                   7402:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7403:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7404:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7405:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7406:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7407:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7408:          vlv= nbcode[Tvaraff[k]][lv];
                   7409:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7410:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7411:        }
1.237     brouard  7412:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7413:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7414:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7415:        }       
1.264     brouard  7416:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7417:        fprintf(ficgp,"\n#\n");
                   7418:        if(invalidvarcomb[k1]){
                   7419:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7420:          continue;
                   7421:        }
                   7422:        
1.241     brouard  7423:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7424:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7425:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7426: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7427:        k=3; /* Offset */
1.268     brouard  7428:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7429:          if(i==1)
                   7430:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7431:          else
                   7432:            fprintf(ficgp,", '' ");
                   7433:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7434:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7435:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7436:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7437:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7438:          /* for (j=2; j<= nlstate ; j ++) */
                   7439:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7440:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7441:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7442:        } /* nlstate */
1.264     brouard  7443:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7444:       } /* end cpt state*/ 
                   7445:     } /* end covariate */  
                   7446:   } /* End if backcast */
                   7447:   
1.223     brouard  7448:   /* 8eme */
1.218     brouard  7449:   if(prevfcast==1){
                   7450:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7451:     
1.237     brouard  7452:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7453:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7454:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7455:        continue;
1.211     brouard  7456:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7457:        strcpy(gplotlabel,"(");      
1.227     brouard  7458:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7459:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7460:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7461:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7462:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7463:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7464:          vlv= nbcode[Tvaraff[k]][lv];
                   7465:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7466:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7467:        }
1.237     brouard  7468:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7469:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7470:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7471:        }       
1.264     brouard  7472:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7473:        fprintf(ficgp,"\n#\n");
                   7474:        if(invalidvarcomb[k1]){
                   7475:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7476:          continue;
                   7477:        }
                   7478:        
                   7479:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7480:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7481:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7482:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7483: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7484: 
                   7485:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7486:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7487:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7488:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7489:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7490:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7491:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7492:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7493:          if(i==istart){
1.227     brouard  7494:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7495:          }else{
                   7496:            fprintf(ficgp,",\\\n '' ");
                   7497:          }
                   7498:          if(cptcoveff ==0){ /* No covariate */
                   7499:            ioffset=2; /* Age is in 2 */
                   7500:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7501:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7502:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7503:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7504:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7505:            if(i==nlstate+1){
                   7506:              fprintf(ficgp," $%d/(1.-$%d)):5 t 'pw.%d' with line lc variable ",        \
                   7507:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7508:              fprintf(ficgp,",\\\n '' ");
                   7509:              fprintf(ficgp," u %d:(",ioffset); 
                   7510:              fprintf(ficgp," (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", \
                   7511:                     offyear,                           \
1.268     brouard  7512:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7513:            }else
1.227     brouard  7514:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7515:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7516:          }else{ /* more than 2 covariates */
                   7517:            if(cptcoveff ==1){
                   7518:              ioffset=4; /* Age is in 4 */
                   7519:            }else{
                   7520:              ioffset=6; /* Age is in 6 */
                   7521:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7522:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7523:            }   
                   7524:            fprintf(ficgp," u %d:(",ioffset); 
                   7525:            kl=0;
                   7526:            strcpy(gplotcondition,"(");
                   7527:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7528:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7529:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7530:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7531:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7532:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7533:              kl++;
                   7534:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7535:              kl++;
                   7536:              if(k <cptcoveff && cptcoveff>1)
                   7537:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7538:            }
                   7539:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7540:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7541:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7542:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7543:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7544:            if(i==nlstate+1){
1.266     brouard  7545:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):5 t 'p.%d' with line lc variable", gplotcondition, \
                   7546:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7547:              fprintf(ficgp,",\\\n '' ");
                   7548:              fprintf(ficgp," u %d:(",ioffset); 
                   7549:              fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \
                   7550:                     offyear,                           \
1.268     brouard  7551:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7552: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7553:            }else{
                   7554:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7555:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7556:            }
                   7557:          } /* end if covariate */
                   7558:        } /* nlstate */
1.264     brouard  7559:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7560:       } /* end cpt state*/
                   7561:     } /* end covariate */
                   7562:   } /* End if prevfcast */
1.227     brouard  7563:   
1.268     brouard  7564:   if(backcast==1){
                   7565:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7566:     
                   7567:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7568:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7569:       if(m != 1 && TKresult[nres]!= k1)
                   7570:        continue;
                   7571:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7572:        strcpy(gplotlabel,"(");      
                   7573:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7574:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7575:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7576:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7577:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7578:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7579:          vlv= nbcode[Tvaraff[k]][lv];
                   7580:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7581:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7582:        }
                   7583:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7584:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7585:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7586:        }       
                   7587:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7588:        fprintf(ficgp,"\n#\n");
                   7589:        if(invalidvarcomb[k1]){
                   7590:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7591:          continue;
                   7592:        }
                   7593:        
                   7594:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7595:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7596:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7597:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7598: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7599: 
                   7600:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7601:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7602:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7603:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7604:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7605:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7606:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7607:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7608:          if(i==istart){
                   7609:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7610:          }else{
                   7611:            fprintf(ficgp,",\\\n '' ");
                   7612:          }
                   7613:          if(cptcoveff ==0){ /* No covariate */
                   7614:            ioffset=2; /* Age is in 2 */
                   7615:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7616:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7617:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7618:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7619:            fprintf(ficgp," u %d:(", ioffset); 
                   7620:            if(i==nlstate+1){
                   7621:              fprintf(ficgp," $%d/(1.-$%d)):5 t 'bw%d' with line lc variable ", \
                   7622:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7623:              fprintf(ficgp,",\\\n '' ");
                   7624:              fprintf(ficgp," u %d:(",ioffset); 
                   7625:              fprintf(ficgp," (($5-$6) == %d ) ? $%d : 1/0):5 with labels center not ", \
                   7626:                     offbyear,                          \
                   7627:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7628:            }else
                   7629:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7630:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7631:          }else{ /* more than 2 covariates */
                   7632:            if(cptcoveff ==1){
                   7633:              ioffset=4; /* Age is in 4 */
                   7634:            }else{
                   7635:              ioffset=6; /* Age is in 6 */
                   7636:              /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7637:              /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7638:            }   
                   7639:            fprintf(ficgp," u %d:(",ioffset); 
                   7640:            kl=0;
                   7641:            strcpy(gplotcondition,"(");
                   7642:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7643:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7644:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7645:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7646:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7647:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7648:              kl++;
                   7649:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7650:              kl++;
                   7651:              if(k <cptcoveff && cptcoveff>1)
                   7652:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7653:            }
                   7654:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7655:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7656:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7657:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7658:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7659:            if(i==nlstate+1){
                   7660:              fprintf(ficgp,"%s ? $%d : 1/0):5 t 'bw%d' with line lc variable", gplotcondition, \
                   7661:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),cpt );
                   7662:              fprintf(ficgp,",\\\n '' ");
                   7663:              fprintf(ficgp," u %d:(",ioffset); 
                   7664:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
                   7665:              fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d : 1/0):5 with labels center not ", gplotcondition, \
                   7666:                     offbyear,                          \
                   7667:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7668: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7669:            }else{
                   7670:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7671:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7672:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7673:            }
                   7674:          } /* end if covariate */
                   7675:        } /* nlstate */
                   7676:        fprintf(ficgp,"\nset out; unset label;\n");
                   7677:       } /* end cpt state*/
                   7678:     } /* end covariate */
                   7679:   } /* End if backcast */
                   7680:   
1.227     brouard  7681:   
1.238     brouard  7682:   /* 9eme writing MLE parameters */
                   7683:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7684:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7685:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7686:     for(k=1; k <=(nlstate+ndeath); k++){
                   7687:       if (k != i) {
1.227     brouard  7688:        fprintf(ficgp,"#   current state %d\n",k);
                   7689:        for(j=1; j <=ncovmodel; j++){
                   7690:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7691:          jk++; 
                   7692:        }
                   7693:        fprintf(ficgp,"\n");
1.126     brouard  7694:       }
                   7695:     }
1.223     brouard  7696:   }
1.187     brouard  7697:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7698:   
1.145     brouard  7699:   /*goto avoid;*/
1.238     brouard  7700:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7701:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7702:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7703:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7704:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7705:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7706:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7707:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7708:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7709:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7710:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7711:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7712:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7713:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7714:   fprintf(ficgp,"#\n");
1.223     brouard  7715:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7716:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7717:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7718:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7719:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7720:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7721:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7722:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7723:        continue;
1.264     brouard  7724:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7725:       strcpy(gplotlabel,"(");
                   7726:       sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);
                   7727:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7728:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7729:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7730:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7731:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7732:        vlv= nbcode[Tvaraff[k]][lv];
                   7733:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7734:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7735:       }
1.237     brouard  7736:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7737:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7738:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7739:       }        
1.264     brouard  7740:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7741:       fprintf(ficgp,"\n#\n");
1.264     brouard  7742:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
                   7743:       fprintf(ficgp,"\nset label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7744:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7745:       if (ng==1){
                   7746:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7747:        fprintf(ficgp,"\nunset log y");
                   7748:       }else if (ng==2){
                   7749:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7750:        fprintf(ficgp,"\nset log y");
                   7751:       }else if (ng==3){
                   7752:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7753:        fprintf(ficgp,"\nset log y");
                   7754:       }else
                   7755:        fprintf(ficgp,"\nunset title ");
                   7756:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7757:       i=1;
                   7758:       for(k2=1; k2<=nlstate; k2++) {
                   7759:        k3=i;
                   7760:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7761:          if (k != k2){
                   7762:            switch( ng) {
                   7763:            case 1:
                   7764:              if(nagesqr==0)
                   7765:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7766:              else /* nagesqr =1 */
                   7767:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7768:              break;
                   7769:            case 2: /* ng=2 */
                   7770:              if(nagesqr==0)
                   7771:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7772:              else /* nagesqr =1 */
                   7773:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7774:              break;
                   7775:            case 3:
                   7776:              if(nagesqr==0)
                   7777:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7778:              else /* nagesqr =1 */
                   7779:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7780:              break;
                   7781:            }
                   7782:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7783:            ijp=1; /* product no age */
                   7784:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7785:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7786:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7787:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7788:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7789:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7790:                    if(DummyV[j]==0){
                   7791:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7792:                    }else{ /* quantitative */
                   7793:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7794:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7795:                    }
                   7796:                    ij++;
1.237     brouard  7797:                  }
1.268     brouard  7798:                } 
                   7799:              }else if(cptcovprod >0){
                   7800:                if(j==Tprod[ijp]) { /* */ 
                   7801:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7802:                  if(ijp <=cptcovprod) { /* Product */
                   7803:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7804:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7805:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7806:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7807:                      }else{ /* Vn is dummy and Vm is quanti */
                   7808:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7809:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7810:                      }
                   7811:                    }else{ /* Vn*Vm Vn is quanti */
                   7812:                      if(DummyV[Tvard[ijp][2]]==0){
                   7813:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7814:                      }else{ /* Both quanti */
                   7815:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7816:                      }
1.237     brouard  7817:                    }
1.268     brouard  7818:                    ijp++;
1.237     brouard  7819:                  }
1.268     brouard  7820:                } /* end Tprod */
1.237     brouard  7821:              } else{  /* simple covariate */
1.264     brouard  7822:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7823:                if(Dummy[j]==0){
                   7824:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7825:                }else{ /* quantitative */
                   7826:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7827:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7828:                }
1.237     brouard  7829:              } /* end simple */
                   7830:            } /* end j */
1.223     brouard  7831:          }else{
                   7832:            i=i-ncovmodel;
                   7833:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7834:              fprintf(ficgp," (1.");
                   7835:          }
1.227     brouard  7836:          
1.223     brouard  7837:          if(ng != 1){
                   7838:            fprintf(ficgp,")/(1");
1.227     brouard  7839:            
1.264     brouard  7840:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7841:              if(nagesqr==0)
1.264     brouard  7842:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7843:              else /* nagesqr =1 */
1.264     brouard  7844:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7845:               
1.223     brouard  7846:              ij=1;
                   7847:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7848:                 if(cptcovage >0){ 
                   7849:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7850:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7851:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7852:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7853:                       ij++;
                   7854:                     }
                   7855:                   }
                   7856:                 }else
                   7857:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7858:              }
                   7859:              fprintf(ficgp,")");
                   7860:            }
                   7861:            fprintf(ficgp,")");
                   7862:            if(ng ==2)
                   7863:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7864:            else /* ng= 3 */
                   7865:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7866:          }else{ /* end ng <> 1 */
                   7867:            if( k !=k2) /* logit p11 is hard to draw */
                   7868:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7869:          }
                   7870:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7871:            fprintf(ficgp,",");
                   7872:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7873:            fprintf(ficgp,",");
                   7874:          i=i+ncovmodel;
                   7875:        } /* end k */
                   7876:       } /* end k2 */
1.264     brouard  7877:       fprintf(ficgp,"\n set out; unset label;\n");
                   7878:     } /* end k1 */
1.223     brouard  7879:   } /* end ng */
                   7880:   /* avoid: */
                   7881:   fflush(ficgp); 
1.126     brouard  7882: }  /* end gnuplot */
                   7883: 
                   7884: 
                   7885: /*************** Moving average **************/
1.219     brouard  7886: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7887:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7888:    
1.222     brouard  7889:    int i, cpt, cptcod;
                   7890:    int modcovmax =1;
                   7891:    int mobilavrange, mob;
                   7892:    int iage=0;
                   7893: 
1.266     brouard  7894:    double sum=0., sumr=0.;
1.222     brouard  7895:    double age;
1.266     brouard  7896:    double *sumnewp, *sumnewm, *sumnewmr;
                   7897:    double *agemingood, *agemaxgood; 
                   7898:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  7899:   
                   7900:   
1.225     brouard  7901:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7902:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7903: 
                   7904:    sumnewp = vector(1,ncovcombmax);
                   7905:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  7906:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  7907:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  7908:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  7909:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  7910:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  7911: 
                   7912:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  7913:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  7914:      sumnewp[cptcod]=0.;
1.266     brouard  7915:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   7916:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  7917:    }
                   7918:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7919:   
1.266     brouard  7920:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7921:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  7922:      else mobilavrange=mobilav;
                   7923:      for (age=bage; age<=fage; age++)
                   7924:        for (i=1; i<=nlstate;i++)
                   7925:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7926:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7927:      /* We keep the original values on the extreme ages bage, fage and for 
                   7928:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7929:        we use a 5 terms etc. until the borders are no more concerned. 
                   7930:      */ 
                   7931:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7932:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  7933:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7934:           sumnewm[cptcod]=0.;
                   7935:           for (i=1; i<=nlstate;i++){
1.222     brouard  7936:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7937:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7938:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7939:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7940:             }
                   7941:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  7942:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7943:           } /* end i */
                   7944:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   7945:         } /* end cptcod */
1.222     brouard  7946:        }/* end age */
                   7947:      }/* end mob */
1.266     brouard  7948:    }else{
                   7949:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  7950:      return -1;
1.266     brouard  7951:    }
                   7952: 
                   7953:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  7954:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7955:      if(invalidvarcomb[cptcod]){
                   7956:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7957:        continue;
                   7958:      }
1.219     brouard  7959: 
1.266     brouard  7960:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   7961:        sumnewm[cptcod]=0.;
                   7962:        sumnewmr[cptcod]=0.;
                   7963:        for (i=1; i<=nlstate;i++){
                   7964:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7965:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7966:        }
                   7967:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7968:         agemingoodr[cptcod]=age;
                   7969:        }
                   7970:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7971:           agemingood[cptcod]=age;
                   7972:        }
                   7973:      } /* age */
                   7974:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  7975:        sumnewm[cptcod]=0.;
1.266     brouard  7976:        sumnewmr[cptcod]=0.;
1.222     brouard  7977:        for (i=1; i<=nlstate;i++){
                   7978:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  7979:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7980:        }
                   7981:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7982:         agemaxgoodr[cptcod]=age;
1.222     brouard  7983:        }
                   7984:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  7985:         agemaxgood[cptcod]=age;
                   7986:        }
                   7987:      } /* age */
                   7988:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   7989:      /* but they will change */
                   7990:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   7991:        sumnewm[cptcod]=0.;
                   7992:        sumnewmr[cptcod]=0.;
                   7993:        for (i=1; i<=nlstate;i++){
                   7994:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7995:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7996:        }
                   7997:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   7998:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7999:           agemaxgoodr[cptcod]=age;  /* age min */
                   8000:           for (i=1; i<=nlstate;i++)
                   8001:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8002:         }else{ /* bad we change the value with the values of good ages */
                   8003:           for (i=1; i<=nlstate;i++){
                   8004:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8005:           } /* i */
                   8006:         } /* end bad */
                   8007:        }else{
                   8008:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8009:           agemaxgood[cptcod]=age;
                   8010:         }else{ /* bad we change the value with the values of good ages */
                   8011:           for (i=1; i<=nlstate;i++){
                   8012:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8013:           } /* i */
                   8014:         } /* end bad */
                   8015:        }/* end else */
                   8016:        sum=0.;sumr=0.;
                   8017:        for (i=1; i<=nlstate;i++){
                   8018:         sum+=mobaverage[(int)age][i][cptcod];
                   8019:         sumr+=probs[(int)age][i][cptcod];
                   8020:        }
                   8021:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8022:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8023:        } /* end bad */
                   8024:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8025:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8026:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8027:        } /* end bad */
                   8028:      }/* age */
1.266     brouard  8029: 
                   8030:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8031:        sumnewm[cptcod]=0.;
1.266     brouard  8032:        sumnewmr[cptcod]=0.;
1.222     brouard  8033:        for (i=1; i<=nlstate;i++){
                   8034:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8035:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8036:        } 
                   8037:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8038:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8039:           agemingoodr[cptcod]=age;
                   8040:           for (i=1; i<=nlstate;i++)
                   8041:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8042:         }else{ /* bad we change the value with the values of good ages */
                   8043:           for (i=1; i<=nlstate;i++){
                   8044:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8045:           } /* i */
                   8046:         } /* end bad */
                   8047:        }else{
                   8048:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8049:           agemingood[cptcod]=age;
                   8050:         }else{ /* bad */
                   8051:           for (i=1; i<=nlstate;i++){
                   8052:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8053:           } /* i */
                   8054:         } /* end bad */
                   8055:        }/* end else */
                   8056:        sum=0.;sumr=0.;
                   8057:        for (i=1; i<=nlstate;i++){
                   8058:         sum+=mobaverage[(int)age][i][cptcod];
                   8059:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8060:        }
1.266     brouard  8061:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8062:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8063:        } /* end bad */
                   8064:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8065:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8066:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8067:        } /* end bad */
                   8068:      }/* age */
1.266     brouard  8069: 
1.222     brouard  8070:                
                   8071:      for (age=bage; age<=fage; age++){
1.235     brouard  8072:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8073:        sumnewp[cptcod]=0.;
                   8074:        sumnewm[cptcod]=0.;
                   8075:        for (i=1; i<=nlstate;i++){
                   8076:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8077:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8078:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8079:        }
                   8080:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8081:      }
                   8082:      /* printf("\n"); */
                   8083:      /* } */
1.266     brouard  8084: 
1.222     brouard  8085:      /* brutal averaging */
1.266     brouard  8086:      /* for (i=1; i<=nlstate;i++){ */
                   8087:      /*   for (age=1; age<=bage; age++){ */
                   8088:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8089:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8090:      /*   }     */
                   8091:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8092:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8093:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8094:      /*   } */
                   8095:      /* } /\* end i status *\/ */
                   8096:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8097:      /*   for (age=1; age<=AGESUP; age++){ */
                   8098:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8099:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8100:      /*   } */
                   8101:      /* } */
1.222     brouard  8102:    }/* end cptcod */
1.266     brouard  8103:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8104:    free_vector(agemaxgood,1, ncovcombmax);
                   8105:    free_vector(agemingood,1, ncovcombmax);
                   8106:    free_vector(agemingoodr,1, ncovcombmax);
                   8107:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8108:    free_vector(sumnewm,1, ncovcombmax);
                   8109:    free_vector(sumnewp,1, ncovcombmax);
                   8110:    return 0;
                   8111:  }/* End movingaverage */
1.218     brouard  8112:  
1.126     brouard  8113: 
                   8114: /************** Forecasting ******************/
1.269   ! brouard  8115:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8116:   /* proj1, year, month, day of starting projection 
                   8117:      agemin, agemax range of age
                   8118:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8119:      anproj2 year of en of projection (same day and month as proj1).
                   8120:   */
1.267     brouard  8121:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8122:   double agec; /* generic age */
                   8123:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8124:   double *popeffectif,*popcount;
                   8125:   double ***p3mat;
1.218     brouard  8126:   /* double ***mobaverage; */
1.126     brouard  8127:   char fileresf[FILENAMELENGTH];
                   8128: 
                   8129:   agelim=AGESUP;
1.211     brouard  8130:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8131:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8132:      We still use firstpass and lastpass as another selection.
                   8133:   */
1.214     brouard  8134:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8135:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8136:  
1.201     brouard  8137:   strcpy(fileresf,"F_"); 
                   8138:   strcat(fileresf,fileresu);
1.126     brouard  8139:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8140:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8141:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8142:   }
1.235     brouard  8143:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8144:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8145: 
1.225     brouard  8146:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8147: 
                   8148: 
                   8149:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8150:   if (stepm<=12) stepsize=1;
                   8151:   if(estepm < stepm){
                   8152:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8153:   }
                   8154:   else  hstepm=estepm;   
                   8155: 
                   8156:   hstepm=hstepm/stepm; 
                   8157:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8158:                                fractional in yp1 */
                   8159:   anprojmean=yp;
                   8160:   yp2=modf((yp1*12),&yp);
                   8161:   mprojmean=yp;
                   8162:   yp1=modf((yp2*30.5),&yp);
                   8163:   jprojmean=yp;
                   8164:   if(jprojmean==0) jprojmean=1;
                   8165:   if(mprojmean==0) jprojmean=1;
                   8166: 
1.227     brouard  8167:   i1=pow(2,cptcoveff);
1.126     brouard  8168:   if (cptcovn < 1){i1=1;}
                   8169:   
                   8170:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8171:   
                   8172:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8173:   
1.126     brouard  8174: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8175:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8176:   for(k=1; k<=i1;k++){
1.253     brouard  8177:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8178:       continue;
1.227     brouard  8179:     if(invalidvarcomb[k]){
                   8180:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8181:       continue;
                   8182:     }
                   8183:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8184:     for(j=1;j<=cptcoveff;j++) {
                   8185:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8186:     }
1.235     brouard  8187:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8188:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8189:     }
1.227     brouard  8190:     fprintf(ficresf," yearproj age");
                   8191:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8192:       for(i=1; i<=nlstate;i++)               
                   8193:        fprintf(ficresf," p%d%d",i,j);
                   8194:       fprintf(ficresf," wp.%d",j);
                   8195:     }
                   8196:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8197:       fprintf(ficresf,"\n");
                   8198:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
                   8199:       for (agec=fage; agec>=(ageminpar-1); agec--){ 
                   8200:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8201:        nhstepm = nhstepm/hstepm; 
                   8202:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8203:        oldm=oldms;savm=savms;
1.268     brouard  8204:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8205:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8206:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8207:        for (h=0; h<=nhstepm; h++){
                   8208:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8209:            break;
                   8210:          }
                   8211:        }
                   8212:        fprintf(ficresf,"\n");
                   8213:        for(j=1;j<=cptcoveff;j++) 
                   8214:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8215:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8216:        
                   8217:        for(j=1; j<=nlstate+ndeath;j++) {
                   8218:          ppij=0.;
                   8219:          for(i=1; i<=nlstate;i++) {
                   8220:            /* if (mobilav>=1)  */
1.269   ! brouard  8221:            ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
1.268     brouard  8222:            /* else { */ /* even if mobilav==-1 we use mobaverage */
                   8223:            /*  ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8224:            /* } */
                   8225:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8226:          } /* end i */
                   8227:          fprintf(ficresf," %.3f", ppij);
                   8228:        }/* end j */
1.227     brouard  8229:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8230:       } /* end agec */
1.266     brouard  8231:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8232:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8233:     } /* end yearp */
                   8234:   } /* end  k */
1.219     brouard  8235:        
1.126     brouard  8236:   fclose(ficresf);
1.215     brouard  8237:   printf("End of Computing forecasting \n");
                   8238:   fprintf(ficlog,"End of Computing forecasting\n");
                   8239: 
1.126     brouard  8240: }
                   8241: 
1.269   ! brouard  8242: /************** Back Forecasting ******************/
        !          8243:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8244:   /* back1, year, month, day of starting backection
                   8245:      agemin, agemax range of age
                   8246:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269   ! brouard  8247:      anback2 year of end of backprojection (same day and month as back1).
        !          8248:      prevacurrent and prev are prevalences.
1.267     brouard  8249:   */
                   8250:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8251:   double agec; /* generic age */
1.268     brouard  8252:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8253:   double *popeffectif,*popcount;
                   8254:   double ***p3mat;
                   8255:   /* double ***mobaverage; */
                   8256:   char fileresfb[FILENAMELENGTH];
                   8257:  
1.268     brouard  8258:   agelim=AGEINF;
1.267     brouard  8259:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8260:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8261:      We still use firstpass and lastpass as another selection.
                   8262:   */
                   8263:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8264:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8265: 
                   8266:   /*Do we need to compute prevalence again?*/
                   8267: 
                   8268:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8269:   
                   8270:   strcpy(fileresfb,"FB_");
                   8271:   strcat(fileresfb,fileresu);
                   8272:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8273:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8274:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8275:   }
                   8276:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8277:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8278:   
                   8279:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8280:   
                   8281:    
                   8282:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8283:   if (stepm<=12) stepsize=1;
                   8284:   if(estepm < stepm){
                   8285:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8286:   }
                   8287:   else  hstepm=estepm;
                   8288:   
                   8289:   hstepm=hstepm/stepm;
                   8290:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8291:                                fractional in yp1 */
                   8292:   anprojmean=yp;
                   8293:   yp2=modf((yp1*12),&yp);
                   8294:   mprojmean=yp;
                   8295:   yp1=modf((yp2*30.5),&yp);
                   8296:   jprojmean=yp;
                   8297:   if(jprojmean==0) jprojmean=1;
                   8298:   if(mprojmean==0) jprojmean=1;
                   8299:   
                   8300:   i1=pow(2,cptcoveff);
                   8301:   if (cptcovn < 1){i1=1;}
                   8302:   
                   8303:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8304:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8305:   
                   8306:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8307:   
                   8308:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8309:   for(k=1; k<=i1;k++){
                   8310:     if(i1 != 1 && TKresult[nres]!= k)
                   8311:       continue;
                   8312:     if(invalidvarcomb[k]){
                   8313:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8314:       continue;
                   8315:     }
1.268     brouard  8316:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8317:     for(j=1;j<=cptcoveff;j++) {
                   8318:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8319:     }
                   8320:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8321:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8322:     }
                   8323:     fprintf(ficresfb," yearbproj age");
                   8324:     for(j=1; j<=nlstate+ndeath;j++){
                   8325:       for(i=1; i<=nlstate;i++)
1.268     brouard  8326:        fprintf(ficresfb," b%d%d",i,j);
                   8327:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8328:     }
                   8329:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8330:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8331:       fprintf(ficresfb,"\n");
                   8332:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.269   ! brouard  8333:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.268     brouard  8334:       for (agec=bage; agec<=agemax-1; agec++){  /* testing */
                   8335:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
                   8336:        nhstepm=(int) rint((agec-agelim)*YEARM/stepm);
1.267     brouard  8337:        nhstepm = nhstepm/hstepm;
                   8338:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8339:        oldm=oldms;savm=savms;
1.268     brouard  8340:        /* computes hbxij at age agec over 1 to nhstepm */
1.267     brouard  8341:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8342:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8343:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8344:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8345:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8346:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8347:            break;
                   8348:          }
                   8349:        }
                   8350:        fprintf(ficresfb,"\n");
                   8351:        for(j=1;j<=cptcoveff;j++)
                   8352:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8353:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8354:        for(i=1; i<=nlstate+ndeath;i++) {
                   8355:          ppij=0.;ppi=0.;
                   8356:          for(j=1; j<=nlstate;j++) {
                   8357:            /* if (mobilav==1) */
1.269   ! brouard  8358:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
        !          8359:            ppi=ppi+prevacurrent[(int)agec][j][k];
        !          8360:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
        !          8361:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8362:              /* else { */
                   8363:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8364:              /* } */
1.268     brouard  8365:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8366:          } /* end j */
                   8367:          if(ppi <0.99){
                   8368:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8369:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8370:          }
                   8371:          fprintf(ficresfb," %.3f", ppij);
                   8372:        }/* end j */
1.267     brouard  8373:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8374:       } /* end agec */
                   8375:     } /* end yearp */
                   8376:   } /* end k */
1.217     brouard  8377:   
1.267     brouard  8378:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8379:   
1.267     brouard  8380:   fclose(ficresfb);
                   8381:   printf("End of Computing Back forecasting \n");
                   8382:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8383:        
1.267     brouard  8384: }
1.217     brouard  8385: 
1.269   ! brouard  8386: /* Variance of prevalence limit: varprlim */
        !          8387:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
        !          8388:     /*------- Variance of period (stable) prevalence------*/   
        !          8389:  
        !          8390:    char fileresvpl[FILENAMELENGTH];  
        !          8391:    FILE *ficresvpl;
        !          8392:    double **oldm, **savm;
        !          8393:    double **varpl; /* Variances of prevalence limits by age */   
        !          8394:    int i1, k, nres, j ;
        !          8395:    
        !          8396:     strcpy(fileresvpl,"VPL_");
        !          8397:     strcat(fileresvpl,fileresu);
        !          8398:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
        !          8399:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
        !          8400:       exit(0);
        !          8401:     }
        !          8402:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
        !          8403:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
        !          8404:     
        !          8405:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
        !          8406:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
        !          8407:     
        !          8408:     i1=pow(2,cptcoveff);
        !          8409:     if (cptcovn < 1){i1=1;}
        !          8410: 
        !          8411:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          8412:     for(k=1; k<=i1;k++){
        !          8413:       if(i1 != 1 && TKresult[nres]!= k)
        !          8414:        continue;
        !          8415:       fprintf(ficresvpl,"\n#****** ");
        !          8416:       printf("\n#****** ");
        !          8417:       fprintf(ficlog,"\n#****** ");
        !          8418:       for(j=1;j<=cptcoveff;j++) {
        !          8419:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
        !          8420:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
        !          8421:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
        !          8422:       }
        !          8423:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
        !          8424:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          8425:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          8426:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          8427:       }        
        !          8428:       fprintf(ficresvpl,"******\n");
        !          8429:       printf("******\n");
        !          8430:       fprintf(ficlog,"******\n");
        !          8431:       
        !          8432:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
        !          8433:       oldm=oldms;savm=savms;
        !          8434:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
        !          8435:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
        !          8436:       /*}*/
        !          8437:     }
        !          8438:     
        !          8439:     fclose(ficresvpl);
        !          8440:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
        !          8441:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
        !          8442: 
        !          8443:  }
        !          8444: /* Variance of back prevalence: varbprlim */
        !          8445:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
        !          8446:       /*------- Variance of back (stable) prevalence------*/
        !          8447: 
        !          8448:    char fileresvbl[FILENAMELENGTH];  
        !          8449:    FILE  *ficresvbl;
        !          8450: 
        !          8451:    double **oldm, **savm;
        !          8452:    double **varbpl; /* Variances of back prevalence limits by age */   
        !          8453:    int i1, k, nres, j ;
        !          8454: 
        !          8455:    strcpy(fileresvbl,"VBL_");
        !          8456:    strcat(fileresvbl,fileresu);
        !          8457:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
        !          8458:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
        !          8459:      exit(0);
        !          8460:    }
        !          8461:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
        !          8462:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
        !          8463:    
        !          8464:    
        !          8465:    i1=pow(2,cptcoveff);
        !          8466:    if (cptcovn < 1){i1=1;}
        !          8467:    
        !          8468:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
        !          8469:      for(k=1; k<=i1;k++){
        !          8470:        if(i1 != 1 && TKresult[nres]!= k)
        !          8471:         continue;
        !          8472:        fprintf(ficresvbl,"\n#****** ");
        !          8473:        printf("\n#****** ");
        !          8474:        fprintf(ficlog,"\n#****** ");
        !          8475:        for(j=1;j<=cptcoveff;j++) {
        !          8476:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
        !          8477:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
        !          8478:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
        !          8479:        }
        !          8480:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
        !          8481:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          8482:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          8483:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
        !          8484:        }
        !          8485:        fprintf(ficresvbl,"******\n");
        !          8486:        printf("******\n");
        !          8487:        fprintf(ficlog,"******\n");
        !          8488:        
        !          8489:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
        !          8490:        oldm=oldms;savm=savms;
        !          8491:        
        !          8492:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
        !          8493:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
        !          8494:        /*}*/
        !          8495:      }
        !          8496:    
        !          8497:    fclose(ficresvbl);
        !          8498:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
        !          8499:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
        !          8500: 
        !          8501:  } /* End of varbprlim */
        !          8502: 
1.126     brouard  8503: /************** Forecasting *****not tested NB*************/
1.227     brouard  8504: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8505:   
1.227     brouard  8506: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8507: /*   int *popage; */
                   8508: /*   double calagedatem, agelim, kk1, kk2; */
                   8509: /*   double *popeffectif,*popcount; */
                   8510: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8511: /*   /\* double ***mobaverage; *\/ */
                   8512: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8513: 
1.227     brouard  8514: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8515: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8516: /*   agelim=AGESUP; */
                   8517: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8518:   
1.227     brouard  8519: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8520:   
                   8521:   
1.227     brouard  8522: /*   strcpy(filerespop,"POP_");  */
                   8523: /*   strcat(filerespop,fileresu); */
                   8524: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8525: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8526: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8527: /*   } */
                   8528: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8529: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8530: 
1.227     brouard  8531: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8532: 
1.227     brouard  8533: /*   /\* if (mobilav!=0) { *\/ */
                   8534: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8535: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8536: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8537: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8538: /*   /\*   } *\/ */
                   8539: /*   /\* } *\/ */
1.126     brouard  8540: 
1.227     brouard  8541: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8542: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8543:   
1.227     brouard  8544: /*   agelim=AGESUP; */
1.126     brouard  8545:   
1.227     brouard  8546: /*   hstepm=1; */
                   8547: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8548:        
1.227     brouard  8549: /*   if (popforecast==1) { */
                   8550: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8551: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8552: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8553: /*     }  */
                   8554: /*     popage=ivector(0,AGESUP); */
                   8555: /*     popeffectif=vector(0,AGESUP); */
                   8556: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8557:     
1.227     brouard  8558: /*     i=1;    */
                   8559: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8560:     
1.227     brouard  8561: /*     imx=i; */
                   8562: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8563: /*   } */
1.218     brouard  8564:   
1.227     brouard  8565: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8566: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8567: /*       k=k+1; */
                   8568: /*       fprintf(ficrespop,"\n#******"); */
                   8569: /*       for(j=1;j<=cptcoveff;j++) { */
                   8570: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8571: /*       } */
                   8572: /*       fprintf(ficrespop,"******\n"); */
                   8573: /*       fprintf(ficrespop,"# Age"); */
                   8574: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8575: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8576:       
1.227     brouard  8577: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8578: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8579:        
1.227     brouard  8580: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8581: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8582: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8583:          
1.227     brouard  8584: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8585: /*       oldm=oldms;savm=savms; */
                   8586: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8587:          
1.227     brouard  8588: /*       for (h=0; h<=nhstepm; h++){ */
                   8589: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8590: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8591: /*         }  */
                   8592: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8593: /*           kk1=0.;kk2=0; */
                   8594: /*           for(i=1; i<=nlstate;i++) {               */
                   8595: /*             if (mobilav==1)  */
                   8596: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8597: /*             else { */
                   8598: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8599: /*             } */
                   8600: /*           } */
                   8601: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8602: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8603: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8604: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8605: /*           } */
                   8606: /*         } */
                   8607: /*         for(i=1; i<=nlstate;i++){ */
                   8608: /*           kk1=0.; */
                   8609: /*           for(j=1; j<=nlstate;j++){ */
                   8610: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8611: /*           } */
                   8612: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8613: /*         } */
1.218     brouard  8614:            
1.227     brouard  8615: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8616: /*           for(j=1; j<=nlstate;j++)  */
                   8617: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8618: /*       } */
                   8619: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8620: /*     } */
                   8621: /*       } */
1.218     brouard  8622:       
1.227     brouard  8623: /*       /\******\/ */
1.218     brouard  8624:       
1.227     brouard  8625: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8626: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8627: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8628: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8629: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8630:          
1.227     brouard  8631: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8632: /*       oldm=oldms;savm=savms; */
                   8633: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8634: /*       for (h=0; h<=nhstepm; h++){ */
                   8635: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8636: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8637: /*         }  */
                   8638: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8639: /*           kk1=0.;kk2=0; */
                   8640: /*           for(i=1; i<=nlstate;i++) {               */
                   8641: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8642: /*           } */
                   8643: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8644: /*         } */
                   8645: /*       } */
                   8646: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8647: /*     } */
                   8648: /*       } */
                   8649: /*     }  */
                   8650: /*   } */
1.218     brouard  8651:   
1.227     brouard  8652: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8653:   
1.227     brouard  8654: /*   if (popforecast==1) { */
                   8655: /*     free_ivector(popage,0,AGESUP); */
                   8656: /*     free_vector(popeffectif,0,AGESUP); */
                   8657: /*     free_vector(popcount,0,AGESUP); */
                   8658: /*   } */
                   8659: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8660: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8661: /*   fclose(ficrespop); */
                   8662: /* } /\* End of popforecast *\/ */
1.218     brouard  8663:  
1.126     brouard  8664: int fileappend(FILE *fichier, char *optionfich)
                   8665: {
                   8666:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8667:     printf("Problem with file: %s\n", optionfich);
                   8668:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8669:     return (0);
                   8670:   }
                   8671:   fflush(fichier);
                   8672:   return (1);
                   8673: }
                   8674: 
                   8675: 
                   8676: /**************** function prwizard **********************/
                   8677: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8678: {
                   8679: 
                   8680:   /* Wizard to print covariance matrix template */
                   8681: 
1.164     brouard  8682:   char ca[32], cb[32];
                   8683:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8684:   int numlinepar;
                   8685: 
                   8686:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8687:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8688:   for(i=1; i <=nlstate; i++){
                   8689:     jj=0;
                   8690:     for(j=1; j <=nlstate+ndeath; j++){
                   8691:       if(j==i) continue;
                   8692:       jj++;
                   8693:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8694:       printf("%1d%1d",i,j);
                   8695:       fprintf(ficparo,"%1d%1d",i,j);
                   8696:       for(k=1; k<=ncovmodel;k++){
                   8697:        /*        printf(" %lf",param[i][j][k]); */
                   8698:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8699:        printf(" 0.");
                   8700:        fprintf(ficparo," 0.");
                   8701:       }
                   8702:       printf("\n");
                   8703:       fprintf(ficparo,"\n");
                   8704:     }
                   8705:   }
                   8706:   printf("# Scales (for hessian or gradient estimation)\n");
                   8707:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8708:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8709:   for(i=1; i <=nlstate; i++){
                   8710:     jj=0;
                   8711:     for(j=1; j <=nlstate+ndeath; j++){
                   8712:       if(j==i) continue;
                   8713:       jj++;
                   8714:       fprintf(ficparo,"%1d%1d",i,j);
                   8715:       printf("%1d%1d",i,j);
                   8716:       fflush(stdout);
                   8717:       for(k=1; k<=ncovmodel;k++){
                   8718:        /*      printf(" %le",delti3[i][j][k]); */
                   8719:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8720:        printf(" 0.");
                   8721:        fprintf(ficparo," 0.");
                   8722:       }
                   8723:       numlinepar++;
                   8724:       printf("\n");
                   8725:       fprintf(ficparo,"\n");
                   8726:     }
                   8727:   }
                   8728:   printf("# Covariance matrix\n");
                   8729: /* # 121 Var(a12)\n\ */
                   8730: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8731: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8732: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8733: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8734: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8735: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8736: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8737:   fflush(stdout);
                   8738:   fprintf(ficparo,"# Covariance matrix\n");
                   8739:   /* # 121 Var(a12)\n\ */
                   8740:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8741:   /* #   ...\n\ */
                   8742:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8743:   
                   8744:   for(itimes=1;itimes<=2;itimes++){
                   8745:     jj=0;
                   8746:     for(i=1; i <=nlstate; i++){
                   8747:       for(j=1; j <=nlstate+ndeath; j++){
                   8748:        if(j==i) continue;
                   8749:        for(k=1; k<=ncovmodel;k++){
                   8750:          jj++;
                   8751:          ca[0]= k+'a'-1;ca[1]='\0';
                   8752:          if(itimes==1){
                   8753:            printf("#%1d%1d%d",i,j,k);
                   8754:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8755:          }else{
                   8756:            printf("%1d%1d%d",i,j,k);
                   8757:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8758:            /*  printf(" %.5le",matcov[i][j]); */
                   8759:          }
                   8760:          ll=0;
                   8761:          for(li=1;li <=nlstate; li++){
                   8762:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8763:              if(lj==li) continue;
                   8764:              for(lk=1;lk<=ncovmodel;lk++){
                   8765:                ll++;
                   8766:                if(ll<=jj){
                   8767:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8768:                  if(ll<jj){
                   8769:                    if(itimes==1){
                   8770:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8771:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8772:                    }else{
                   8773:                      printf(" 0.");
                   8774:                      fprintf(ficparo," 0.");
                   8775:                    }
                   8776:                  }else{
                   8777:                    if(itimes==1){
                   8778:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8779:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8780:                    }else{
                   8781:                      printf(" 0.");
                   8782:                      fprintf(ficparo," 0.");
                   8783:                    }
                   8784:                  }
                   8785:                }
                   8786:              } /* end lk */
                   8787:            } /* end lj */
                   8788:          } /* end li */
                   8789:          printf("\n");
                   8790:          fprintf(ficparo,"\n");
                   8791:          numlinepar++;
                   8792:        } /* end k*/
                   8793:       } /*end j */
                   8794:     } /* end i */
                   8795:   } /* end itimes */
                   8796: 
                   8797: } /* end of prwizard */
                   8798: /******************* Gompertz Likelihood ******************************/
                   8799: double gompertz(double x[])
                   8800: { 
                   8801:   double A,B,L=0.0,sump=0.,num=0.;
                   8802:   int i,n=0; /* n is the size of the sample */
                   8803: 
1.220     brouard  8804:   for (i=1;i<=imx ; i++) {
1.126     brouard  8805:     sump=sump+weight[i];
                   8806:     /*    sump=sump+1;*/
                   8807:     num=num+1;
                   8808:   }
                   8809:  
                   8810:  
                   8811:   /* for (i=0; i<=imx; i++) 
                   8812:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8813: 
                   8814:   for (i=1;i<=imx ; i++)
                   8815:     {
                   8816:       if (cens[i] == 1 && wav[i]>1)
                   8817:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8818:       
                   8819:       if (cens[i] == 0 && wav[i]>1)
                   8820:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8821:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8822:       
                   8823:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8824:       if (wav[i] > 1 ) { /* ??? */
                   8825:        L=L+A*weight[i];
                   8826:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8827:       }
                   8828:     }
                   8829: 
                   8830:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8831:  
                   8832:   return -2*L*num/sump;
                   8833: }
                   8834: 
1.136     brouard  8835: #ifdef GSL
                   8836: /******************* Gompertz_f Likelihood ******************************/
                   8837: double gompertz_f(const gsl_vector *v, void *params)
                   8838: { 
                   8839:   double A,B,LL=0.0,sump=0.,num=0.;
                   8840:   double *x= (double *) v->data;
                   8841:   int i,n=0; /* n is the size of the sample */
                   8842: 
                   8843:   for (i=0;i<=imx-1 ; i++) {
                   8844:     sump=sump+weight[i];
                   8845:     /*    sump=sump+1;*/
                   8846:     num=num+1;
                   8847:   }
                   8848:  
                   8849:  
                   8850:   /* for (i=0; i<=imx; i++) 
                   8851:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8852:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8853:   for (i=1;i<=imx ; i++)
                   8854:     {
                   8855:       if (cens[i] == 1 && wav[i]>1)
                   8856:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8857:       
                   8858:       if (cens[i] == 0 && wav[i]>1)
                   8859:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8860:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8861:       
                   8862:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8863:       if (wav[i] > 1 ) { /* ??? */
                   8864:        LL=LL+A*weight[i];
                   8865:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8866:       }
                   8867:     }
                   8868: 
                   8869:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8870:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8871:  
                   8872:   return -2*LL*num/sump;
                   8873: }
                   8874: #endif
                   8875: 
1.126     brouard  8876: /******************* Printing html file ***********/
1.201     brouard  8877: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8878:                  int lastpass, int stepm, int weightopt, char model[],\
                   8879:                  int imx,  double p[],double **matcov,double agemortsup){
                   8880:   int i,k;
                   8881: 
                   8882:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8883:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8884:   for (i=1;i<=2;i++) 
                   8885:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8886:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8887:   fprintf(fichtm,"</ul>");
                   8888: 
                   8889: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8890: 
                   8891:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8892: 
                   8893:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8894:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8895: 
                   8896:  
                   8897:   fflush(fichtm);
                   8898: }
                   8899: 
                   8900: /******************* Gnuplot file **************/
1.201     brouard  8901: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8902: 
                   8903:   char dirfileres[132],optfileres[132];
1.164     brouard  8904: 
1.126     brouard  8905:   int ng;
                   8906: 
                   8907: 
                   8908:   /*#ifdef windows */
                   8909:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8910:     /*#endif */
                   8911: 
                   8912: 
                   8913:   strcpy(dirfileres,optionfilefiname);
                   8914:   strcpy(optfileres,"vpl");
1.199     brouard  8915:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8916:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8917:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8918:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8919:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8920: 
                   8921: } 
                   8922: 
1.136     brouard  8923: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8924: {
1.126     brouard  8925: 
1.136     brouard  8926:   /*-------- data file ----------*/
                   8927:   FILE *fic;
                   8928:   char dummy[]="                         ";
1.240     brouard  8929:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8930:   int lstra;
1.136     brouard  8931:   int linei, month, year,iout;
                   8932:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8933:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8934:   char *stratrunc;
1.223     brouard  8935: 
1.240     brouard  8936:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8937:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8938: 
1.240     brouard  8939:   for(v=1; v <=ncovcol;v++){
                   8940:     DummyV[v]=0;
                   8941:     FixedV[v]=0;
                   8942:   }
                   8943:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8944:     DummyV[v]=1;
                   8945:     FixedV[v]=0;
                   8946:   }
                   8947:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8948:     DummyV[v]=0;
                   8949:     FixedV[v]=1;
                   8950:   }
                   8951:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8952:     DummyV[v]=1;
                   8953:     FixedV[v]=1;
                   8954:   }
                   8955:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8956:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8957:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8958:   }
1.126     brouard  8959: 
1.136     brouard  8960:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8961:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8962:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8963:   }
1.126     brouard  8964: 
1.136     brouard  8965:   i=1;
                   8966:   linei=0;
                   8967:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8968:     linei=linei+1;
                   8969:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8970:       if(line[j] == '\t')
                   8971:        line[j] = ' ';
                   8972:     }
                   8973:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   8974:       ;
                   8975:     };
                   8976:     line[j+1]=0;  /* Trims blanks at end of line */
                   8977:     if(line[0]=='#'){
                   8978:       fprintf(ficlog,"Comment line\n%s\n",line);
                   8979:       printf("Comment line\n%s\n",line);
                   8980:       continue;
                   8981:     }
                   8982:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  8983:     strcpy(line, linetmp);
1.223     brouard  8984:     
                   8985:     /* Loops on waves */
                   8986:     for (j=maxwav;j>=1;j--){
                   8987:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  8988:        cutv(stra, strb, line, ' '); 
                   8989:        if(strb[0]=='.') { /* Missing value */
                   8990:          lval=-1;
                   8991:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   8992:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   8993:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   8994:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   8995:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   8996:            return 1;
                   8997:          }
                   8998:        }else{
                   8999:          errno=0;
                   9000:          /* what_kind_of_number(strb); */
                   9001:          dval=strtod(strb,&endptr); 
                   9002:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9003:          /* if(strb != endptr && *endptr == '\0') */
                   9004:          /*    dval=dlval; */
                   9005:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9006:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9007:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9008:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9009:            return 1;
                   9010:          }
                   9011:          cotqvar[j][iv][i]=dval; 
                   9012:          cotvar[j][ntv+iv][i]=dval; 
                   9013:        }
                   9014:        strcpy(line,stra);
1.223     brouard  9015:       }/* end loop ntqv */
1.225     brouard  9016:       
1.223     brouard  9017:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9018:        cutv(stra, strb, line, ' '); 
                   9019:        if(strb[0]=='.') { /* Missing value */
                   9020:          lval=-1;
                   9021:        }else{
                   9022:          errno=0;
                   9023:          lval=strtol(strb,&endptr,10); 
                   9024:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9025:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9026:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9027:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9028:            return 1;
                   9029:          }
                   9030:        }
                   9031:        if(lval <-1 || lval >1){
                   9032:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9033:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9034:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9035:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9036:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9037:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9038:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9039:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9040:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9041:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9042:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9043:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9044:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9045:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9046:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9047:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9048:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9049:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9050:          return 1;
                   9051:        }
                   9052:        cotvar[j][iv][i]=(double)(lval);
                   9053:        strcpy(line,stra);
1.223     brouard  9054:       }/* end loop ntv */
1.225     brouard  9055:       
1.223     brouard  9056:       /* Statuses  at wave */
1.137     brouard  9057:       cutv(stra, strb, line, ' '); 
1.223     brouard  9058:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9059:        lval=-1;
1.136     brouard  9060:       }else{
1.238     brouard  9061:        errno=0;
                   9062:        lval=strtol(strb,&endptr,10); 
                   9063:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9064:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9065:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9066:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9067:          return 1;
                   9068:        }
1.136     brouard  9069:       }
1.225     brouard  9070:       
1.136     brouard  9071:       s[j][i]=lval;
1.225     brouard  9072:       
1.223     brouard  9073:       /* Date of Interview */
1.136     brouard  9074:       strcpy(line,stra);
                   9075:       cutv(stra, strb,line,' ');
1.169     brouard  9076:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9077:       }
1.169     brouard  9078:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9079:        month=99;
                   9080:        year=9999;
1.136     brouard  9081:       }else{
1.225     brouard  9082:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9083:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9084:        return 1;
1.136     brouard  9085:       }
                   9086:       anint[j][i]= (double) year; 
                   9087:       mint[j][i]= (double)month; 
                   9088:       strcpy(line,stra);
1.223     brouard  9089:     } /* End loop on waves */
1.225     brouard  9090:     
1.223     brouard  9091:     /* Date of death */
1.136     brouard  9092:     cutv(stra, strb,line,' '); 
1.169     brouard  9093:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9094:     }
1.169     brouard  9095:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9096:       month=99;
                   9097:       year=9999;
                   9098:     }else{
1.141     brouard  9099:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9100:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9101:       return 1;
1.136     brouard  9102:     }
                   9103:     andc[i]=(double) year; 
                   9104:     moisdc[i]=(double) month; 
                   9105:     strcpy(line,stra);
                   9106:     
1.223     brouard  9107:     /* Date of birth */
1.136     brouard  9108:     cutv(stra, strb,line,' '); 
1.169     brouard  9109:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9110:     }
1.169     brouard  9111:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9112:       month=99;
                   9113:       year=9999;
                   9114:     }else{
1.141     brouard  9115:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9116:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9117:       return 1;
1.136     brouard  9118:     }
                   9119:     if (year==9999) {
1.141     brouard  9120:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9121:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9122:       return 1;
                   9123:       
1.136     brouard  9124:     }
                   9125:     annais[i]=(double)(year);
                   9126:     moisnais[i]=(double)(month); 
                   9127:     strcpy(line,stra);
1.225     brouard  9128:     
1.223     brouard  9129:     /* Sample weight */
1.136     brouard  9130:     cutv(stra, strb,line,' '); 
                   9131:     errno=0;
                   9132:     dval=strtod(strb,&endptr); 
                   9133:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9134:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9135:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9136:       fflush(ficlog);
                   9137:       return 1;
                   9138:     }
                   9139:     weight[i]=dval; 
                   9140:     strcpy(line,stra);
1.225     brouard  9141:     
1.223     brouard  9142:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9143:       cutv(stra, strb, line, ' '); 
                   9144:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9145:        lval=-1;
1.223     brouard  9146:       }else{
1.225     brouard  9147:        errno=0;
                   9148:        /* what_kind_of_number(strb); */
                   9149:        dval=strtod(strb,&endptr);
                   9150:        /* if(strb != endptr && *endptr == '\0') */
                   9151:        /*   dval=dlval; */
                   9152:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9153:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9154:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9155:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9156:          return 1;
                   9157:        }
                   9158:        coqvar[iv][i]=dval; 
1.226     brouard  9159:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9160:       }
                   9161:       strcpy(line,stra);
                   9162:     }/* end loop nqv */
1.136     brouard  9163:     
1.223     brouard  9164:     /* Covariate values */
1.136     brouard  9165:     for (j=ncovcol;j>=1;j--){
                   9166:       cutv(stra, strb,line,' '); 
1.223     brouard  9167:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9168:        lval=-1;
1.136     brouard  9169:       }else{
1.225     brouard  9170:        errno=0;
                   9171:        lval=strtol(strb,&endptr,10); 
                   9172:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9173:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9174:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9175:          return 1;
                   9176:        }
1.136     brouard  9177:       }
                   9178:       if(lval <-1 || lval >1){
1.225     brouard  9179:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9180:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9181:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9182:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9183:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9184:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9185:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9186:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9187:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9188:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9189:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9190:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9191:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9192:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9193:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9194:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9195:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9196:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9197:        return 1;
1.136     brouard  9198:       }
                   9199:       covar[j][i]=(double)(lval);
                   9200:       strcpy(line,stra);
                   9201:     }  
                   9202:     lstra=strlen(stra);
1.225     brouard  9203:     
1.136     brouard  9204:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9205:       stratrunc = &(stra[lstra-9]);
                   9206:       num[i]=atol(stratrunc);
                   9207:     }
                   9208:     else
                   9209:       num[i]=atol(stra);
                   9210:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9211:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9212:     
                   9213:     i=i+1;
                   9214:   } /* End loop reading  data */
1.225     brouard  9215:   
1.136     brouard  9216:   *imax=i-1; /* Number of individuals */
                   9217:   fclose(fic);
1.225     brouard  9218:   
1.136     brouard  9219:   return (0);
1.164     brouard  9220:   /* endread: */
1.225     brouard  9221:   printf("Exiting readdata: ");
                   9222:   fclose(fic);
                   9223:   return (1);
1.223     brouard  9224: }
1.126     brouard  9225: 
1.234     brouard  9226: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9227:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9228:   while (*p2 == ' ')
1.234     brouard  9229:     p2++; 
                   9230:   /* while ((*p1++ = *p2++) !=0) */
                   9231:   /*   ; */
                   9232:   /* do */
                   9233:   /*   while (*p2 == ' ') */
                   9234:   /*     p2++; */
                   9235:   /* while (*p1++ == *p2++); */
                   9236:   *stri=p2; 
1.145     brouard  9237: }
                   9238: 
1.235     brouard  9239: int decoderesult ( char resultline[], int nres)
1.230     brouard  9240: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9241: {
1.235     brouard  9242:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9243:   char resultsav[MAXLINE];
1.234     brouard  9244:   int resultmodel[MAXLINE];
                   9245:   int modelresult[MAXLINE];
1.230     brouard  9246:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9247: 
1.234     brouard  9248:   removefirstspace(&resultline);
1.233     brouard  9249:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9250: 
                   9251:   if (strstr(resultline,"v") !=0){
                   9252:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9253:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9254:     return 1;
                   9255:   }
                   9256:   trimbb(resultsav, resultline);
                   9257:   if (strlen(resultsav) >1){
                   9258:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9259:   }
1.253     brouard  9260:   if(j == 0){ /* Resultline but no = */
                   9261:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9262:     return (0);
                   9263:   }
                   9264:     
1.234     brouard  9265:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9266:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9267:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9268:   }
                   9269:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9270:     if(nbocc(resultsav,'=') >1){
                   9271:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9272:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9273:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9274:     }else
                   9275:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9276:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9277:     
1.230     brouard  9278:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9279:     Tvarsel[k]=atoi(strc);
                   9280:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9281:     /* cptcovsel++;     */
                   9282:     if (nbocc(stra,'=') >0)
                   9283:       strcpy(resultsav,stra); /* and analyzes it */
                   9284:   }
1.235     brouard  9285:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9286:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9287:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9288:       match=0;
1.236     brouard  9289:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9290:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9291:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9292:          match=1;
                   9293:          break;
                   9294:        }
                   9295:       }
                   9296:       if(match == 0){
                   9297:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9298:       }
                   9299:     }
                   9300:   }
1.235     brouard  9301:   /* Checking for missing or useless values in comparison of current model needs */
                   9302:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9303:     match=0;
1.235     brouard  9304:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9305:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9306:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9307:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9308:          ++match;
                   9309:        }
                   9310:       }
                   9311:     }
                   9312:     if(match == 0){
                   9313:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9314:     }else if(match > 1){
                   9315:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9316:     }
                   9317:   }
1.235     brouard  9318:       
1.234     brouard  9319:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9320:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9321:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9322:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9323:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9324:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9325:   /*    1 0 0 0 */
                   9326:   /*    2 1 0 0 */
                   9327:   /*    3 0 1 0 */ 
                   9328:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9329:   /*    5 0 0 1 */
                   9330:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9331:   /*    7 0 1 1 */
                   9332:   /*    8 1 1 1 */
1.237     brouard  9333:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9334:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9335:   /* V5*age V5 known which value for nres?  */
                   9336:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9337:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9338:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9339:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9340:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9341:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9342:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9343:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9344:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9345:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9346:       k4++;;
                   9347:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9348:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9349:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9350:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9351:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9352:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9353:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9354:       k4q++;;
                   9355:     }
                   9356:   }
1.234     brouard  9357:   
1.235     brouard  9358:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9359:   return (0);
                   9360: }
1.235     brouard  9361: 
1.230     brouard  9362: int decodemodel( char model[], int lastobs)
                   9363:  /**< This routine decodes the model and returns:
1.224     brouard  9364:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9365:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9366:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9367:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9368:        * - cptcovage number of covariates with age*products =2
                   9369:        * - cptcovs number of simple covariates
                   9370:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9371:        *     which is a new column after the 9 (ncovcol) variables. 
                   9372:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9373:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9374:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9375:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9376:        */
1.136     brouard  9377: {
1.238     brouard  9378:   int i, j, k, ks, v;
1.227     brouard  9379:   int  j1, k1, k2, k3, k4;
1.136     brouard  9380:   char modelsav[80];
1.145     brouard  9381:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9382:   char *strpt;
1.136     brouard  9383: 
1.145     brouard  9384:   /*removespace(model);*/
1.136     brouard  9385:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9386:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9387:     if (strstr(model,"AGE") !=0){
1.192     brouard  9388:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9389:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9390:       return 1;
                   9391:     }
1.141     brouard  9392:     if (strstr(model,"v") !=0){
                   9393:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9394:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9395:       return 1;
                   9396:     }
1.187     brouard  9397:     strcpy(modelsav,model); 
                   9398:     if ((strpt=strstr(model,"age*age")) !=0){
                   9399:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9400:       if(strpt != model){
1.234     brouard  9401:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9402:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9403:  corresponding column of parameters.\n",model);
1.234     brouard  9404:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9405:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9406:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9407:        return 1;
1.225     brouard  9408:       }
1.187     brouard  9409:       nagesqr=1;
                   9410:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9411:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9412:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9413:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9414:       else 
1.234     brouard  9415:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9416:     }else
                   9417:       nagesqr=0;
                   9418:     if (strlen(modelsav) >1){
                   9419:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9420:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9421:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9422:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9423:                     * cst, age and age*age 
                   9424:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9425:       /* including age products which are counted in cptcovage.
                   9426:        * but the covariates which are products must be treated 
                   9427:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9428:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9429:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9430:       
                   9431:       
1.187     brouard  9432:       /*   Design
                   9433:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9434:        *  <          ncovcol=8                >
                   9435:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9436:        *   k=  1    2      3       4     5       6      7        8
                   9437:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9438:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9439:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9440:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9441:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9442:        *  Tage[++cptcovage]=k
                   9443:        *       if products, new covar are created after ncovcol with k1
                   9444:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9445:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9446:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9447:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9448:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9449:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9450:        *  <          ncovcol=8                >
                   9451:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9452:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9453:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9454:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9455:        * p Tprod[1]@2={                         6, 5}
                   9456:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9457:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9458:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9459:        *How to reorganize?
                   9460:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9461:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9462:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9463:        * Struct []
                   9464:        */
1.225     brouard  9465:       
1.187     brouard  9466:       /* This loop fills the array Tvar from the string 'model'.*/
                   9467:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9468:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9469:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9470:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9471:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9472:       /*       k=1 Tvar[1]=2 (from V2) */
                   9473:       /*       k=5 Tvar[5] */
                   9474:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9475:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9476:       /*       } */
1.198     brouard  9477:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9478:       /*
                   9479:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9480:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9481:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9482:       }
1.187     brouard  9483:       cptcovage=0;
                   9484:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9485:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9486:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9487:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9488:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9489:        /*scanf("%d",i);*/
                   9490:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9491:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9492:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9493:            /* covar is not filled and then is empty */
                   9494:            cptcovprod--;
                   9495:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9496:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9497:            Typevar[k]=1;  /* 1 for age product */
                   9498:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9499:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9500:            /*printf("stre=%s ", stre);*/
                   9501:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9502:            cptcovprod--;
                   9503:            cutl(stre,strb,strc,'V');
                   9504:            Tvar[k]=atoi(stre);
                   9505:            Typevar[k]=1;  /* 1 for age product */
                   9506:            cptcovage++;
                   9507:            Tage[cptcovage]=k;
                   9508:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9509:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9510:            cptcovn++;
                   9511:            cptcovprodnoage++;k1++;
                   9512:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9513:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9514:                                                because this model-covariate is a construction we invent a new column
                   9515:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9516:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9517:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9518:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9519:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9520:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9521:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9522:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9523:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9524:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9525:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9526:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9527:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9528:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9529:            for (i=1; i<=lastobs;i++){
                   9530:              /* Computes the new covariate which is a product of
                   9531:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9532:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9533:            }
                   9534:          } /* End age is not in the model */
                   9535:        } /* End if model includes a product */
                   9536:        else { /* no more sum */
                   9537:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9538:          /*  scanf("%d",i);*/
                   9539:          cutl(strd,strc,strb,'V');
                   9540:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9541:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9542:          Tvar[k]=atoi(strd);
                   9543:          Typevar[k]=0;  /* 0 for simple covariates */
                   9544:        }
                   9545:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9546:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9547:                                  scanf("%d",i);*/
1.187     brouard  9548:       } /* end of loop + on total covariates */
                   9549:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9550:   } /* end if strlen(model == 0) */
1.136     brouard  9551:   
                   9552:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9553:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9554:   
1.136     brouard  9555:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9556:      printf("cptcovprod=%d ", cptcovprod);
                   9557:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9558:      scanf("%d ",i);*/
                   9559: 
                   9560: 
1.230     brouard  9561: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9562:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9563: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9564:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9565:    k =           1    2   3     4       5       6      7      8        9
                   9566:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9567:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9568:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9569:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9570:          Tmodelind[combination of covar]=k;
1.225     brouard  9571: */  
                   9572: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9573:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9574:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9575:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9576:   printf("Model=%s\n\
                   9577: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9578: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9579: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9580:   fprintf(ficlog,"Model=%s\n\
                   9581: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9582: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9583: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9584:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9585:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9586:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9587:       Fixed[k]= 0;
                   9588:       Dummy[k]= 0;
1.225     brouard  9589:       ncoveff++;
1.232     brouard  9590:       ncovf++;
1.234     brouard  9591:       nsd++;
                   9592:       modell[k].maintype= FTYPE;
                   9593:       TvarsD[nsd]=Tvar[k];
                   9594:       TvarsDind[nsd]=k;
                   9595:       TvarF[ncovf]=Tvar[k];
                   9596:       TvarFind[ncovf]=k;
                   9597:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9598:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9599:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9600:       Fixed[k]= 0;
                   9601:       Dummy[k]= 0;
                   9602:       ncoveff++;
                   9603:       ncovf++;
                   9604:       modell[k].maintype= FTYPE;
                   9605:       TvarF[ncovf]=Tvar[k];
                   9606:       TvarFind[ncovf]=k;
1.230     brouard  9607:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9608:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9609:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9610:       Fixed[k]= 0;
                   9611:       Dummy[k]= 1;
1.230     brouard  9612:       nqfveff++;
1.234     brouard  9613:       modell[k].maintype= FTYPE;
                   9614:       modell[k].subtype= FQ;
                   9615:       nsq++;
                   9616:       TvarsQ[nsq]=Tvar[k];
                   9617:       TvarsQind[nsq]=k;
1.232     brouard  9618:       ncovf++;
1.234     brouard  9619:       TvarF[ncovf]=Tvar[k];
                   9620:       TvarFind[ncovf]=k;
1.231     brouard  9621:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9622:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9623:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9624:       Fixed[k]= 1;
                   9625:       Dummy[k]= 0;
1.225     brouard  9626:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9627:       modell[k].maintype= VTYPE;
                   9628:       modell[k].subtype= VD;
                   9629:       nsd++;
                   9630:       TvarsD[nsd]=Tvar[k];
                   9631:       TvarsDind[nsd]=k;
                   9632:       ncovv++; /* Only simple time varying variables */
                   9633:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9634:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9635:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9636:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9637:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9638:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9639:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9640:       Fixed[k]= 1;
                   9641:       Dummy[k]= 1;
                   9642:       nqtveff++;
                   9643:       modell[k].maintype= VTYPE;
                   9644:       modell[k].subtype= VQ;
                   9645:       ncovv++; /* Only simple time varying variables */
                   9646:       nsq++;
                   9647:       TvarsQ[nsq]=Tvar[k];
                   9648:       TvarsQind[nsq]=k;
                   9649:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9650:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9651:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9652:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9653:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9654:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9655:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9656:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9657:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9658:       ncova++;
                   9659:       TvarA[ncova]=Tvar[k];
                   9660:       TvarAind[ncova]=k;
1.231     brouard  9661:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9662:        Fixed[k]= 2;
                   9663:        Dummy[k]= 2;
                   9664:        modell[k].maintype= ATYPE;
                   9665:        modell[k].subtype= APFD;
                   9666:        /* ncoveff++; */
1.227     brouard  9667:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9668:        Fixed[k]= 2;
                   9669:        Dummy[k]= 3;
                   9670:        modell[k].maintype= ATYPE;
                   9671:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9672:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9673:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9674:        Fixed[k]= 3;
                   9675:        Dummy[k]= 2;
                   9676:        modell[k].maintype= ATYPE;
                   9677:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9678:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9679:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9680:        Fixed[k]= 3;
                   9681:        Dummy[k]= 3;
                   9682:        modell[k].maintype= ATYPE;
                   9683:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9684:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9685:       }
                   9686:     }else if (Typevar[k] == 2) {  /* product without age */
                   9687:       k1=Tposprod[k];
                   9688:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9689:        if(Tvard[k1][2] <=ncovcol){
                   9690:          Fixed[k]= 1;
                   9691:          Dummy[k]= 0;
                   9692:          modell[k].maintype= FTYPE;
                   9693:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9694:          ncovf++; /* Fixed variables without age */
                   9695:          TvarF[ncovf]=Tvar[k];
                   9696:          TvarFind[ncovf]=k;
                   9697:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9698:          Fixed[k]= 0;  /* or 2 ?*/
                   9699:          Dummy[k]= 1;
                   9700:          modell[k].maintype= FTYPE;
                   9701:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9702:          ncovf++; /* Varying variables without age */
                   9703:          TvarF[ncovf]=Tvar[k];
                   9704:          TvarFind[ncovf]=k;
                   9705:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9706:          Fixed[k]= 1;
                   9707:          Dummy[k]= 0;
                   9708:          modell[k].maintype= VTYPE;
                   9709:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9710:          ncovv++; /* Varying variables without age */
                   9711:          TvarV[ncovv]=Tvar[k];
                   9712:          TvarVind[ncovv]=k;
                   9713:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9714:          Fixed[k]= 1;
                   9715:          Dummy[k]= 1;
                   9716:          modell[k].maintype= VTYPE;
                   9717:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9718:          ncovv++; /* Varying variables without age */
                   9719:          TvarV[ncovv]=Tvar[k];
                   9720:          TvarVind[ncovv]=k;
                   9721:        }
1.227     brouard  9722:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9723:        if(Tvard[k1][2] <=ncovcol){
                   9724:          Fixed[k]= 0;  /* or 2 ?*/
                   9725:          Dummy[k]= 1;
                   9726:          modell[k].maintype= FTYPE;
                   9727:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9728:          ncovf++; /* Fixed variables without age */
                   9729:          TvarF[ncovf]=Tvar[k];
                   9730:          TvarFind[ncovf]=k;
                   9731:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9732:          Fixed[k]= 1;
                   9733:          Dummy[k]= 1;
                   9734:          modell[k].maintype= VTYPE;
                   9735:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9736:          ncovv++; /* Varying variables without age */
                   9737:          TvarV[ncovv]=Tvar[k];
                   9738:          TvarVind[ncovv]=k;
                   9739:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9740:          Fixed[k]= 1;
                   9741:          Dummy[k]= 1;
                   9742:          modell[k].maintype= VTYPE;
                   9743:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9744:          ncovv++; /* Varying variables without age */
                   9745:          TvarV[ncovv]=Tvar[k];
                   9746:          TvarVind[ncovv]=k;
                   9747:          ncovv++; /* Varying variables without age */
                   9748:          TvarV[ncovv]=Tvar[k];
                   9749:          TvarVind[ncovv]=k;
                   9750:        }
1.227     brouard  9751:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9752:        if(Tvard[k1][2] <=ncovcol){
                   9753:          Fixed[k]= 1;
                   9754:          Dummy[k]= 1;
                   9755:          modell[k].maintype= VTYPE;
                   9756:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9757:          ncovv++; /* Varying variables without age */
                   9758:          TvarV[ncovv]=Tvar[k];
                   9759:          TvarVind[ncovv]=k;
                   9760:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9761:          Fixed[k]= 1;
                   9762:          Dummy[k]= 1;
                   9763:          modell[k].maintype= VTYPE;
                   9764:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9765:          ncovv++; /* Varying variables without age */
                   9766:          TvarV[ncovv]=Tvar[k];
                   9767:          TvarVind[ncovv]=k;
                   9768:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9769:          Fixed[k]= 1;
                   9770:          Dummy[k]= 0;
                   9771:          modell[k].maintype= VTYPE;
                   9772:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9773:          ncovv++; /* Varying variables without age */
                   9774:          TvarV[ncovv]=Tvar[k];
                   9775:          TvarVind[ncovv]=k;
                   9776:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9777:          Fixed[k]= 1;
                   9778:          Dummy[k]= 1;
                   9779:          modell[k].maintype= VTYPE;
                   9780:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9781:          ncovv++; /* Varying variables without age */
                   9782:          TvarV[ncovv]=Tvar[k];
                   9783:          TvarVind[ncovv]=k;
                   9784:        }
1.227     brouard  9785:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9786:        if(Tvard[k1][2] <=ncovcol){
                   9787:          Fixed[k]= 1;
                   9788:          Dummy[k]= 1;
                   9789:          modell[k].maintype= VTYPE;
                   9790:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9791:          ncovv++; /* Varying variables without age */
                   9792:          TvarV[ncovv]=Tvar[k];
                   9793:          TvarVind[ncovv]=k;
                   9794:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9795:          Fixed[k]= 1;
                   9796:          Dummy[k]= 1;
                   9797:          modell[k].maintype= VTYPE;
                   9798:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9799:          ncovv++; /* Varying variables without age */
                   9800:          TvarV[ncovv]=Tvar[k];
                   9801:          TvarVind[ncovv]=k;
                   9802:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9803:          Fixed[k]= 1;
                   9804:          Dummy[k]= 1;
                   9805:          modell[k].maintype= VTYPE;
                   9806:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9807:          ncovv++; /* Varying variables without age */
                   9808:          TvarV[ncovv]=Tvar[k];
                   9809:          TvarVind[ncovv]=k;
                   9810:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9811:          Fixed[k]= 1;
                   9812:          Dummy[k]= 1;
                   9813:          modell[k].maintype= VTYPE;
                   9814:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9815:          ncovv++; /* Varying variables without age */
                   9816:          TvarV[ncovv]=Tvar[k];
                   9817:          TvarVind[ncovv]=k;
                   9818:        }
1.227     brouard  9819:       }else{
1.240     brouard  9820:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9821:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9822:       } /*end k1*/
1.225     brouard  9823:     }else{
1.226     brouard  9824:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9825:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9826:     }
1.227     brouard  9827:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9828:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9829:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9830:   }
                   9831:   /* Searching for doublons in the model */
                   9832:   for(k1=1; k1<= cptcovt;k1++){
                   9833:     for(k2=1; k2 <k1;k2++){
                   9834:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9835:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9836:          if(Tvar[k1]==Tvar[k2]){
                   9837:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9838:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9839:            return(1);
                   9840:          }
                   9841:        }else if (Typevar[k1] ==2){
                   9842:          k3=Tposprod[k1];
                   9843:          k4=Tposprod[k2];
                   9844:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9845:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9846:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9847:            return(1);
                   9848:          }
                   9849:        }
1.227     brouard  9850:       }
                   9851:     }
1.225     brouard  9852:   }
                   9853:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9854:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9855:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9856:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9857:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9858:   /*endread:*/
1.225     brouard  9859:   printf("Exiting decodemodel: ");
                   9860:   return (1);
1.136     brouard  9861: }
                   9862: 
1.169     brouard  9863: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9864: {/* Check ages at death */
1.136     brouard  9865:   int i, m;
1.218     brouard  9866:   int firstone=0;
                   9867:   
1.136     brouard  9868:   for (i=1; i<=imx; i++) {
                   9869:     for(m=2; (m<= maxwav); m++) {
                   9870:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9871:        anint[m][i]=9999;
1.216     brouard  9872:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9873:          s[m][i]=-1;
1.136     brouard  9874:       }
                   9875:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9876:        *nberr = *nberr + 1;
1.218     brouard  9877:        if(firstone == 0){
                   9878:          firstone=1;
1.260     brouard  9879:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9880:        }
1.262     brouard  9881:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9882:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9883:       }
                   9884:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9885:        (*nberr)++;
1.259     brouard  9886:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9887:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9888:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9889:       }
                   9890:     }
                   9891:   }
                   9892: 
                   9893:   for (i=1; i<=imx; i++)  {
                   9894:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9895:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9896:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9897:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9898:          if(agedc[i]>0){
                   9899:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9900:              agev[m][i]=agedc[i];
1.214     brouard  9901:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9902:            }else {
1.136     brouard  9903:              if ((int)andc[i]!=9999){
                   9904:                nbwarn++;
                   9905:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9906:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9907:                agev[m][i]=-1;
                   9908:              }
                   9909:            }
1.169     brouard  9910:          } /* agedc > 0 */
1.214     brouard  9911:        } /* end if */
1.136     brouard  9912:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9913:                                 years but with the precision of a month */
                   9914:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9915:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9916:            agev[m][i]=1;
                   9917:          else if(agev[m][i] < *agemin){ 
                   9918:            *agemin=agev[m][i];
                   9919:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9920:          }
                   9921:          else if(agev[m][i] >*agemax){
                   9922:            *agemax=agev[m][i];
1.156     brouard  9923:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9924:          }
                   9925:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9926:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9927:        } /* en if 9*/
1.136     brouard  9928:        else { /* =9 */
1.214     brouard  9929:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9930:          agev[m][i]=1;
                   9931:          s[m][i]=-1;
                   9932:        }
                   9933:       }
1.214     brouard  9934:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9935:        agev[m][i]=1;
1.214     brouard  9936:       else{
                   9937:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9938:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9939:        agev[m][i]=0;
                   9940:       }
                   9941:     } /* End for lastpass */
                   9942:   }
1.136     brouard  9943:     
                   9944:   for (i=1; i<=imx; i++)  {
                   9945:     for(m=firstpass; (m<=lastpass); m++){
                   9946:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9947:        (*nberr)++;
1.136     brouard  9948:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9949:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9950:        return 1;
                   9951:       }
                   9952:     }
                   9953:   }
                   9954: 
                   9955:   /*for (i=1; i<=imx; i++){
                   9956:   for (m=firstpass; (m<lastpass); m++){
                   9957:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9958: }
                   9959: 
                   9960: }*/
                   9961: 
                   9962: 
1.139     brouard  9963:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9964:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9965: 
                   9966:   return (0);
1.164     brouard  9967:  /* endread:*/
1.136     brouard  9968:     printf("Exiting calandcheckages: ");
                   9969:     return (1);
                   9970: }
                   9971: 
1.172     brouard  9972: #if defined(_MSC_VER)
                   9973: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9974: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   9975: //#include "stdafx.h"
                   9976: //#include <stdio.h>
                   9977: //#include <tchar.h>
                   9978: //#include <windows.h>
                   9979: //#include <iostream>
                   9980: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   9981: 
                   9982: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9983: 
                   9984: BOOL IsWow64()
                   9985: {
                   9986:        BOOL bIsWow64 = FALSE;
                   9987: 
                   9988:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   9989:        //  (HANDLE, PBOOL);
                   9990: 
                   9991:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   9992: 
                   9993:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   9994:        const char funcName[] = "IsWow64Process";
                   9995:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   9996:                GetProcAddress(module, funcName);
                   9997: 
                   9998:        if (NULL != fnIsWow64Process)
                   9999:        {
                   10000:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10001:                        &bIsWow64))
                   10002:                        //throw std::exception("Unknown error");
                   10003:                        printf("Unknown error\n");
                   10004:        }
                   10005:        return bIsWow64 != FALSE;
                   10006: }
                   10007: #endif
1.177     brouard  10008: 
1.191     brouard  10009: void syscompilerinfo(int logged)
1.167     brouard  10010:  {
                   10011:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10012:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10013:    /* /GS /W3 /Gy
                   10014:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10015:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10016:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10017:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10018:    */ 
                   10019:    /* 64 bits */
1.185     brouard  10020:    /*
                   10021:      /GS /W3 /Gy
                   10022:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10023:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10024:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10025:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10026:    /* Optimization are useless and O3 is slower than O2 */
                   10027:    /*
                   10028:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10029:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10030:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10031:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10032:    */
1.186     brouard  10033:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10034:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10035:       /PDB:"visual studio
                   10036:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10037:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10038:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10039:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10040:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10041:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10042:       uiAccess='false'"
                   10043:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10044:       /NOLOGO /TLBID:1
                   10045:    */
1.177     brouard  10046: #if defined __INTEL_COMPILER
1.178     brouard  10047: #if defined(__GNUC__)
                   10048:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10049: #endif
1.177     brouard  10050: #elif defined(__GNUC__) 
1.179     brouard  10051: #ifndef  __APPLE__
1.174     brouard  10052: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10053: #endif
1.177     brouard  10054:    struct utsname sysInfo;
1.178     brouard  10055:    int cross = CROSS;
                   10056:    if (cross){
                   10057:           printf("Cross-");
1.191     brouard  10058:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10059:    }
1.174     brouard  10060: #endif
                   10061: 
1.171     brouard  10062: #include <stdint.h>
1.178     brouard  10063: 
1.191     brouard  10064:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10065: #if defined(__clang__)
1.191     brouard  10066:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10067: #endif
                   10068: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10069:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10070: #endif
                   10071: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10072:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10073: #endif
                   10074: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10075:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10076: #endif
                   10077: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10078:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10079: #endif
                   10080: #if defined(_MSC_VER)
1.191     brouard  10081:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10082: #endif
                   10083: #if defined(__PGI)
1.191     brouard  10084:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10085: #endif
                   10086: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10087:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10088: #endif
1.191     brouard  10089:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10090:    
1.167     brouard  10091: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10092: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10093:     // Windows (x64 and x86)
1.191     brouard  10094:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10095: #elif __unix__ // all unices, not all compilers
                   10096:     // Unix
1.191     brouard  10097:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10098: #elif __linux__
                   10099:     // linux
1.191     brouard  10100:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10101: #elif __APPLE__
1.174     brouard  10102:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10103:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10104: #endif
                   10105: 
                   10106: /*  __MINGW32__          */
                   10107: /*  __CYGWIN__  */
                   10108: /* __MINGW64__  */
                   10109: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10110: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10111: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10112: /* _WIN64  // Defined for applications for Win64. */
                   10113: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10114: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10115: 
1.167     brouard  10116: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10117:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10118: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10119:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10120: #else
1.191     brouard  10121:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10122: #endif
                   10123: 
1.169     brouard  10124: #if defined(__GNUC__)
                   10125: # if defined(__GNUC_PATCHLEVEL__)
                   10126: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10127:                             + __GNUC_MINOR__ * 100 \
                   10128:                             + __GNUC_PATCHLEVEL__)
                   10129: # else
                   10130: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10131:                             + __GNUC_MINOR__ * 100)
                   10132: # endif
1.174     brouard  10133:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10134:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10135: 
                   10136:    if (uname(&sysInfo) != -1) {
                   10137:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10138:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10139:    }
                   10140:    else
                   10141:       perror("uname() error");
1.179     brouard  10142:    //#ifndef __INTEL_COMPILER 
                   10143: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10144:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10145:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10146: #endif
1.169     brouard  10147: #endif
1.172     brouard  10148: 
                   10149:    //   void main()
                   10150:    //   {
1.169     brouard  10151: #if defined(_MSC_VER)
1.174     brouard  10152:    if (IsWow64()){
1.191     brouard  10153:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10154:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10155:    }
                   10156:    else{
1.191     brouard  10157:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10158:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10159:    }
1.172     brouard  10160:    //     printf("\nPress Enter to continue...");
                   10161:    //     getchar();
                   10162:    //   }
                   10163: 
1.169     brouard  10164: #endif
                   10165:    
1.167     brouard  10166: 
1.219     brouard  10167: }
1.136     brouard  10168: 
1.219     brouard  10169: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10170:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10171:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10172:   /* double ftolpl = 1.e-10; */
1.180     brouard  10173:   double age, agebase, agelim;
1.203     brouard  10174:   double tot;
1.180     brouard  10175: 
1.202     brouard  10176:   strcpy(filerespl,"PL_");
                   10177:   strcat(filerespl,fileresu);
                   10178:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10179:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10180:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10181:   }
1.227     brouard  10182:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10183:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10184:   pstamp(ficrespl);
1.203     brouard  10185:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10186:   fprintf(ficrespl,"#Age ");
                   10187:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10188:   fprintf(ficrespl,"\n");
1.180     brouard  10189:   
1.219     brouard  10190:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10191: 
1.219     brouard  10192:   agebase=ageminpar;
                   10193:   agelim=agemaxpar;
1.180     brouard  10194: 
1.227     brouard  10195:   /* i1=pow(2,ncoveff); */
1.234     brouard  10196:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10197:   if (cptcovn < 1){i1=1;}
1.180     brouard  10198: 
1.238     brouard  10199:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10200:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10201:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10202:        continue;
1.235     brouard  10203: 
1.238     brouard  10204:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10205:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10206:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10207:       /* k=k+1; */
                   10208:       /* to clean */
                   10209:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10210:       fprintf(ficrespl,"#******");
                   10211:       printf("#******");
                   10212:       fprintf(ficlog,"#******");
                   10213:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10214:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10215:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10216:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10217:       }
                   10218:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10219:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10220:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10221:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10222:       }
                   10223:       fprintf(ficrespl,"******\n");
                   10224:       printf("******\n");
                   10225:       fprintf(ficlog,"******\n");
                   10226:       if(invalidvarcomb[k]){
                   10227:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10228:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10229:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10230:        continue;
                   10231:       }
1.219     brouard  10232: 
1.238     brouard  10233:       fprintf(ficrespl,"#Age ");
                   10234:       for(j=1;j<=cptcoveff;j++) {
                   10235:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10236:       }
                   10237:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10238:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10239:     
1.238     brouard  10240:       for (age=agebase; age<=agelim; age++){
                   10241:        /* for (age=agebase; age<=agebase; age++){ */
                   10242:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10243:        fprintf(ficrespl,"%.0f ",age );
                   10244:        for(j=1;j<=cptcoveff;j++)
                   10245:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10246:        tot=0.;
                   10247:        for(i=1; i<=nlstate;i++){
                   10248:          tot +=  prlim[i][i];
                   10249:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10250:        }
                   10251:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10252:       } /* Age */
                   10253:       /* was end of cptcod */
                   10254:     } /* cptcov */
                   10255:   } /* nres */
1.219     brouard  10256:   return 0;
1.180     brouard  10257: }
                   10258: 
1.218     brouard  10259: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10260:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10261:        
                   10262:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10263:    * at any age between ageminpar and agemaxpar
                   10264:         */
1.235     brouard  10265:   int i, j, k, i1, nres=0 ;
1.217     brouard  10266:   /* double ftolpl = 1.e-10; */
                   10267:   double age, agebase, agelim;
                   10268:   double tot;
1.218     brouard  10269:   /* double ***mobaverage; */
                   10270:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10271: 
                   10272:   strcpy(fileresplb,"PLB_");
                   10273:   strcat(fileresplb,fileresu);
                   10274:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10275:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10276:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10277:   }
                   10278:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10279:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10280:   pstamp(ficresplb);
                   10281:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10282:   fprintf(ficresplb,"#Age ");
                   10283:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10284:   fprintf(ficresplb,"\n");
                   10285:   
1.218     brouard  10286:   
                   10287:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10288:   
                   10289:   agebase=ageminpar;
                   10290:   agelim=agemaxpar;
                   10291:   
                   10292:   
1.227     brouard  10293:   i1=pow(2,cptcoveff);
1.218     brouard  10294:   if (cptcovn < 1){i1=1;}
1.227     brouard  10295:   
1.238     brouard  10296:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10297:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10298:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10299:        continue;
                   10300:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10301:       fprintf(ficresplb,"#******");
                   10302:       printf("#******");
                   10303:       fprintf(ficlog,"#******");
                   10304:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10305:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10306:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10307:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10308:       }
                   10309:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10310:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10311:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10312:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10313:       }
                   10314:       fprintf(ficresplb,"******\n");
                   10315:       printf("******\n");
                   10316:       fprintf(ficlog,"******\n");
                   10317:       if(invalidvarcomb[k]){
                   10318:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10319:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10320:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10321:        continue;
                   10322:       }
1.218     brouard  10323:     
1.238     brouard  10324:       fprintf(ficresplb,"#Age ");
                   10325:       for(j=1;j<=cptcoveff;j++) {
                   10326:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10327:       }
                   10328:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10329:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10330:     
                   10331:     
1.238     brouard  10332:       for (age=agebase; age<=agelim; age++){
                   10333:        /* for (age=agebase; age<=agebase; age++){ */
                   10334:        if(mobilavproj > 0){
                   10335:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10336:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10337:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10338:        }else if (mobilavproj == 0){
                   10339:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10340:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10341:          exit(1);
                   10342:        }else{
                   10343:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10344:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10345:          /* printf("TOTOT\n"); */
                   10346:           /* exit(1); */
1.238     brouard  10347:        }
                   10348:        fprintf(ficresplb,"%.0f ",age );
                   10349:        for(j=1;j<=cptcoveff;j++)
                   10350:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10351:        tot=0.;
                   10352:        for(i=1; i<=nlstate;i++){
                   10353:          tot +=  bprlim[i][i];
                   10354:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10355:        }
                   10356:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10357:       } /* Age */
                   10358:       /* was end of cptcod */
1.255     brouard  10359:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10360:     } /* end of any combination */
                   10361:   } /* end of nres */  
1.218     brouard  10362:   /* hBijx(p, bage, fage); */
                   10363:   /* fclose(ficrespijb); */
                   10364:   
                   10365:   return 0;
1.217     brouard  10366: }
1.218     brouard  10367:  
1.180     brouard  10368: int hPijx(double *p, int bage, int fage){
                   10369:     /*------------- h Pij x at various ages ------------*/
                   10370: 
                   10371:   int stepsize;
                   10372:   int agelim;
                   10373:   int hstepm;
                   10374:   int nhstepm;
1.235     brouard  10375:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10376: 
                   10377:   double agedeb;
                   10378:   double ***p3mat;
                   10379: 
1.201     brouard  10380:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10381:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10382:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10383:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10384:     }
                   10385:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10386:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10387:   
                   10388:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10389:     /*if (stepm<=24) stepsize=2;*/
                   10390: 
                   10391:     agelim=AGESUP;
                   10392:     hstepm=stepsize*YEARM; /* Every year of age */
                   10393:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10394:                
1.180     brouard  10395:     /* hstepm=1;   aff par mois*/
                   10396:     pstamp(ficrespij);
                   10397:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10398:     i1= pow(2,cptcoveff);
1.218     brouard  10399:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10400:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10401:                /*      k=k+1;  */
1.235     brouard  10402:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10403:     for(k=1; k<=i1;k++){
1.253     brouard  10404:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10405:        continue;
1.183     brouard  10406:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10407:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10408:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10409:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10410:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10411:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10412:       }
1.183     brouard  10413:       fprintf(ficrespij,"******\n");
                   10414:       
                   10415:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10416:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10417:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10418:        
                   10419:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10420:        
1.183     brouard  10421:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10422:        oldm=oldms;savm=savms;
1.235     brouard  10423:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10424:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10425:        for(i=1; i<=nlstate;i++)
                   10426:          for(j=1; j<=nlstate+ndeath;j++)
                   10427:            fprintf(ficrespij," %1d-%1d",i,j);
                   10428:        fprintf(ficrespij,"\n");
                   10429:        for (h=0; h<=nhstepm; h++){
                   10430:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10431:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10432:          for(i=1; i<=nlstate;i++)
                   10433:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10434:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10435:          fprintf(ficrespij,"\n");
                   10436:        }
1.183     brouard  10437:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10438:        fprintf(ficrespij,"\n");
                   10439:       }
1.180     brouard  10440:       /*}*/
                   10441:     }
1.218     brouard  10442:     return 0;
1.180     brouard  10443: }
1.218     brouard  10444:  
                   10445:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10446:     /*------------- h Bij x at various ages ------------*/
                   10447: 
                   10448:   int stepsize;
1.218     brouard  10449:   /* int agelim; */
                   10450:        int ageminl;
1.217     brouard  10451:   int hstepm;
                   10452:   int nhstepm;
1.238     brouard  10453:   int h, i, i1, j, k, nres;
1.218     brouard  10454:        
1.217     brouard  10455:   double agedeb;
                   10456:   double ***p3mat;
1.218     brouard  10457:        
                   10458:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10459:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10460:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10461:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10462:   }
                   10463:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10464:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10465:   
                   10466:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10467:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10468:   
1.218     brouard  10469:   /* agelim=AGESUP; */
                   10470:   ageminl=30;
                   10471:   hstepm=stepsize*YEARM; /* Every year of age */
                   10472:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10473:   
                   10474:   /* hstepm=1;   aff par mois*/
                   10475:   pstamp(ficrespijb);
1.255     brouard  10476:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10477:   i1= pow(2,cptcoveff);
1.218     brouard  10478:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10479:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10480:   /*   k=k+1;  */
1.238     brouard  10481:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10482:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10483:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10484:        continue;
                   10485:       fprintf(ficrespijb,"\n#****** ");
                   10486:       for(j=1;j<=cptcoveff;j++)
                   10487:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10488:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10489:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10490:       }
                   10491:       fprintf(ficrespijb,"******\n");
1.264     brouard  10492:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10493:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10494:        continue;
                   10495:       }
                   10496:       
                   10497:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10498:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10499:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10500:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10501:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10502:        
                   10503:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10504:        
1.266     brouard  10505:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10506:        /* and memory limitations if stepm is small */
                   10507: 
1.238     brouard  10508:        /* oldm=oldms;savm=savms; */
                   10509:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10510:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10511:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10512:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10513:        for(i=1; i<=nlstate;i++)
                   10514:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10515:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10516:        fprintf(ficrespijb,"\n");
1.238     brouard  10517:        for (h=0; h<=nhstepm; h++){
                   10518:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10519:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10520:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10521:          for(i=1; i<=nlstate;i++)
                   10522:            for(j=1; j<=nlstate+ndeath;j++)
                   10523:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10524:          fprintf(ficrespijb,"\n");
                   10525:        }
                   10526:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10527:        fprintf(ficrespijb,"\n");
                   10528:       } /* end age deb */
                   10529:     } /* end combination */
                   10530:   } /* end nres */
1.218     brouard  10531:   return 0;
                   10532:  } /*  hBijx */
1.217     brouard  10533: 
1.180     brouard  10534: 
1.136     brouard  10535: /***********************************************/
                   10536: /**************** Main Program *****************/
                   10537: /***********************************************/
                   10538: 
                   10539: int main(int argc, char *argv[])
                   10540: {
                   10541: #ifdef GSL
                   10542:   const gsl_multimin_fminimizer_type *T;
                   10543:   size_t iteri = 0, it;
                   10544:   int rval = GSL_CONTINUE;
                   10545:   int status = GSL_SUCCESS;
                   10546:   double ssval;
                   10547: #endif
                   10548:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10549:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10550:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10551:   int jj, ll, li, lj, lk;
1.136     brouard  10552:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10553:   int num_filled;
1.136     brouard  10554:   int itimes;
                   10555:   int NDIM=2;
                   10556:   int vpopbased=0;
1.235     brouard  10557:   int nres=0;
1.258     brouard  10558:   int endishere=0;
1.136     brouard  10559: 
1.164     brouard  10560:   char ca[32], cb[32];
1.136     brouard  10561:   /*  FILE *fichtm; *//* Html File */
                   10562:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10563:   struct stat info;
1.191     brouard  10564:   double agedeb=0.;
1.194     brouard  10565: 
                   10566:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10567:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10568: 
1.165     brouard  10569:   double fret;
1.191     brouard  10570:   double dum=0.; /* Dummy variable */
1.136     brouard  10571:   double ***p3mat;
1.218     brouard  10572:   /* double ***mobaverage; */
1.164     brouard  10573: 
                   10574:   char line[MAXLINE];
1.197     brouard  10575:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10576: 
1.234     brouard  10577:   char  modeltemp[MAXLINE];
1.230     brouard  10578:   char resultline[MAXLINE];
                   10579:   
1.136     brouard  10580:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10581:   char *tok, *val; /* pathtot */
1.136     brouard  10582:   int firstobs=1, lastobs=10;
1.195     brouard  10583:   int c,  h , cpt, c2;
1.191     brouard  10584:   int jl=0;
                   10585:   int i1, j1, jk, stepsize=0;
1.194     brouard  10586:   int count=0;
                   10587: 
1.164     brouard  10588:   int *tab; 
1.136     brouard  10589:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10590:   int backcast=0;
1.136     brouard  10591:   int mobilav=0,popforecast=0;
1.191     brouard  10592:   int hstepm=0, nhstepm=0;
1.136     brouard  10593:   int agemortsup;
                   10594:   float  sumlpop=0.;
                   10595:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10596:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10597: 
1.191     brouard  10598:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10599:   double ftolpl=FTOL;
                   10600:   double **prlim;
1.217     brouard  10601:   double **bprlim;
1.136     brouard  10602:   double ***param; /* Matrix of parameters */
1.251     brouard  10603:   double ***paramstart; /* Matrix of starting parameter values */
                   10604:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10605:   double **matcov; /* Matrix of covariance */
1.203     brouard  10606:   double **hess; /* Hessian matrix */
1.136     brouard  10607:   double ***delti3; /* Scale */
                   10608:   double *delti; /* Scale */
                   10609:   double ***eij, ***vareij;
                   10610:   double **varpl; /* Variances of prevalence limits by age */
1.269   ! brouard  10611: 
1.136     brouard  10612:   double *epj, vepp;
1.164     brouard  10613: 
1.136     brouard  10614:   double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
1.217     brouard  10615:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000;
                   10616: 
1.136     brouard  10617:   double **ximort;
1.145     brouard  10618:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10619:   int *dcwave;
                   10620: 
1.164     brouard  10621:   char z[1]="c";
1.136     brouard  10622: 
                   10623:   /*char  *strt;*/
                   10624:   char strtend[80];
1.126     brouard  10625: 
1.164     brouard  10626: 
1.126     brouard  10627: /*   setlocale (LC_ALL, ""); */
                   10628: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10629: /*   textdomain (PACKAGE); */
                   10630: /*   setlocale (LC_CTYPE, ""); */
                   10631: /*   setlocale (LC_MESSAGES, ""); */
                   10632: 
                   10633:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10634:   rstart_time = time(NULL);  
                   10635:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10636:   start_time = *localtime(&rstart_time);
1.126     brouard  10637:   curr_time=start_time;
1.157     brouard  10638:   /*tml = *localtime(&start_time.tm_sec);*/
                   10639:   /* strcpy(strstart,asctime(&tml)); */
                   10640:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10641: 
                   10642: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10643: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10644: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10645: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10646: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10647: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10648: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10649: /*   strt=asctime(&tmg); */
                   10650: /*   printf("Time(after) =%s",strstart);  */
                   10651: /*  (void) time (&time_value);
                   10652: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10653: *  tm = *localtime(&time_value);
                   10654: *  strstart=asctime(&tm);
                   10655: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10656: */
                   10657: 
                   10658:   nberr=0; /* Number of errors and warnings */
                   10659:   nbwarn=0;
1.184     brouard  10660: #ifdef WIN32
                   10661:   _getcwd(pathcd, size);
                   10662: #else
1.126     brouard  10663:   getcwd(pathcd, size);
1.184     brouard  10664: #endif
1.191     brouard  10665:   syscompilerinfo(0);
1.196     brouard  10666:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10667:   if(argc <=1){
                   10668:     printf("\nEnter the parameter file name: ");
1.205     brouard  10669:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10670:       printf("ERROR Empty parameter file name\n");
                   10671:       goto end;
                   10672:     }
1.126     brouard  10673:     i=strlen(pathr);
                   10674:     if(pathr[i-1]=='\n')
                   10675:       pathr[i-1]='\0';
1.156     brouard  10676:     i=strlen(pathr);
1.205     brouard  10677:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10678:       pathr[i-1]='\0';
1.205     brouard  10679:     }
                   10680:     i=strlen(pathr);
                   10681:     if( i==0 ){
                   10682:       printf("ERROR Empty parameter file name\n");
                   10683:       goto end;
                   10684:     }
                   10685:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10686:       printf("Pathr |%s|\n",pathr);
                   10687:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10688:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10689:       strcpy (pathtot, val);
                   10690:       if(pathr[0] == '\0') break; /* Dirty */
                   10691:     }
                   10692:   }
                   10693:   else{
                   10694:     strcpy(pathtot,argv[1]);
                   10695:   }
                   10696:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10697:   /*cygwin_split_path(pathtot,path,optionfile);
                   10698:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10699:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10700: 
                   10701:   /* Split argv[0], imach program to get pathimach */
                   10702:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10703:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10704:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10705:  /*   strcpy(pathimach,argv[0]); */
                   10706:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10707:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10708:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10709: #ifdef WIN32
                   10710:   _chdir(path); /* Can be a relative path */
                   10711:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10712: #else
1.126     brouard  10713:   chdir(path); /* Can be a relative path */
1.184     brouard  10714:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10715: #endif
                   10716:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10717:   strcpy(command,"mkdir ");
                   10718:   strcat(command,optionfilefiname);
                   10719:   if((outcmd=system(command)) != 0){
1.169     brouard  10720:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10721:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10722:     /* fclose(ficlog); */
                   10723: /*     exit(1); */
                   10724:   }
                   10725: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10726: /*     perror("mkdir"); */
                   10727: /*   } */
                   10728: 
                   10729:   /*-------- arguments in the command line --------*/
                   10730: 
1.186     brouard  10731:   /* Main Log file */
1.126     brouard  10732:   strcat(filelog, optionfilefiname);
                   10733:   strcat(filelog,".log");    /* */
                   10734:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10735:     printf("Problem with logfile %s\n",filelog);
                   10736:     goto end;
                   10737:   }
                   10738:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10739:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10740:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10741:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10742:  path=%s \n\
                   10743:  optionfile=%s\n\
                   10744:  optionfilext=%s\n\
1.156     brouard  10745:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10746: 
1.197     brouard  10747:   syscompilerinfo(1);
1.167     brouard  10748: 
1.126     brouard  10749:   printf("Local time (at start):%s",strstart);
                   10750:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10751:   fflush(ficlog);
                   10752: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10753: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10754: 
                   10755:   /* */
                   10756:   strcpy(fileres,"r");
                   10757:   strcat(fileres, optionfilefiname);
1.201     brouard  10758:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10759:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10760:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10761: 
1.186     brouard  10762:   /* Main ---------arguments file --------*/
1.126     brouard  10763: 
                   10764:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10765:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10766:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10767:     fflush(ficlog);
1.149     brouard  10768:     /* goto end; */
                   10769:     exit(70); 
1.126     brouard  10770:   }
                   10771: 
                   10772: 
                   10773: 
                   10774:   strcpy(filereso,"o");
1.201     brouard  10775:   strcat(filereso,fileresu);
1.126     brouard  10776:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10777:     printf("Problem with Output resultfile: %s\n", filereso);
                   10778:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10779:     fflush(ficlog);
                   10780:     goto end;
                   10781:   }
                   10782: 
                   10783:   /* Reads comments: lines beginning with '#' */
                   10784:   numlinepar=0;
1.197     brouard  10785: 
                   10786:     /* First parameter line */
                   10787:   while(fgets(line, MAXLINE, ficpar)) {
                   10788:     /* If line starts with a # it is a comment */
                   10789:     if (line[0] == '#') {
                   10790:       numlinepar++;
                   10791:       fputs(line,stdout);
                   10792:       fputs(line,ficparo);
                   10793:       fputs(line,ficlog);
                   10794:       continue;
                   10795:     }else
                   10796:       break;
                   10797:   }
                   10798:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10799:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10800:     if (num_filled != 5) {
                   10801:       printf("Should be 5 parameters\n");
                   10802:     }
1.126     brouard  10803:     numlinepar++;
1.197     brouard  10804:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10805:   }
                   10806:   /* Second parameter line */
                   10807:   while(fgets(line, MAXLINE, ficpar)) {
                   10808:     /* If line starts with a # it is a comment */
                   10809:     if (line[0] == '#') {
                   10810:       numlinepar++;
                   10811:       fputs(line,stdout);
                   10812:       fputs(line,ficparo);
                   10813:       fputs(line,ficlog);
                   10814:       continue;
                   10815:     }else
                   10816:       break;
                   10817:   }
1.223     brouard  10818:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10819:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10820:     if (num_filled != 11) {
                   10821:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10822:       printf("but line=%s\n",line);
1.197     brouard  10823:     }
1.223     brouard  10824:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10825:   }
1.203     brouard  10826:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10827:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10828:   /* Third parameter line */
                   10829:   while(fgets(line, MAXLINE, ficpar)) {
                   10830:     /* If line starts with a # it is a comment */
                   10831:     if (line[0] == '#') {
                   10832:       numlinepar++;
                   10833:       fputs(line,stdout);
                   10834:       fputs(line,ficparo);
                   10835:       fputs(line,ficlog);
                   10836:       continue;
                   10837:     }else
                   10838:       break;
                   10839:   }
1.201     brouard  10840:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263     brouard  10841:     if (num_filled == 0){
                   10842:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10843:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10844:       model[0]='\0';
                   10845:       goto end;
                   10846:     } else if (num_filled != 1){
1.197     brouard  10847:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10848:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10849:       model[0]='\0';
                   10850:       goto end;
                   10851:     }
                   10852:     else{
                   10853:       if (model[0]=='+'){
                   10854:        for(i=1; i<=strlen(model);i++)
                   10855:          modeltemp[i-1]=model[i];
1.201     brouard  10856:        strcpy(model,modeltemp); 
1.197     brouard  10857:       }
                   10858:     }
1.199     brouard  10859:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10860:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10861:   }
                   10862:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10863:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10864:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10865:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10866:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10867:   fflush(ficlog);
1.190     brouard  10868:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10869:   if(model[0]=='#'){
1.187     brouard  10870:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10871:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10872:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10873:     if(mle != -1){
                   10874:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10875:       exit(1);
                   10876:     }
                   10877:   }
1.126     brouard  10878:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10879:     ungetc(c,ficpar);
                   10880:     fgets(line, MAXLINE, ficpar);
                   10881:     numlinepar++;
1.195     brouard  10882:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10883:       z[0]=line[1];
                   10884:     }
                   10885:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10886:     fputs(line, stdout);
                   10887:     //puts(line);
1.126     brouard  10888:     fputs(line,ficparo);
                   10889:     fputs(line,ficlog);
                   10890:   }
                   10891:   ungetc(c,ficpar);
                   10892: 
                   10893:    
1.145     brouard  10894:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  10895:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   10896:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   10897:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  10898:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10899:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10900:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10901:   */
                   10902:   if (strlen(model)>1) 
1.187     brouard  10903:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10904:   else
1.187     brouard  10905:     ncovmodel=2; /* Constant and age */
1.133     brouard  10906:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10907:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10908:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10909:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10910:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10911:     fflush(stdout);
                   10912:     fclose (ficlog);
                   10913:     goto end;
                   10914:   }
1.126     brouard  10915:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10916:   delti=delti3[1][1];
                   10917:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10918:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10919: /* We could also provide initial parameters values giving by simple logistic regression 
                   10920:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10921:       /* for(i=1;i<nlstate;i++){ */
                   10922:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10923:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10924:       /* } */
1.126     brouard  10925:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10926:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10927:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10928:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10929:     fclose (ficparo);
                   10930:     fclose (ficlog);
                   10931:     goto end;
                   10932:     exit(0);
1.220     brouard  10933:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10934:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10935:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10936:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10937:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10938:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10939:     hess=matrix(1,npar,1,npar);
1.220     brouard  10940:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10941:     /* Read guessed parameters */
1.126     brouard  10942:     /* Reads comments: lines beginning with '#' */
                   10943:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10944:       ungetc(c,ficpar);
                   10945:       fgets(line, MAXLINE, ficpar);
                   10946:       numlinepar++;
1.141     brouard  10947:       fputs(line,stdout);
1.126     brouard  10948:       fputs(line,ficparo);
                   10949:       fputs(line,ficlog);
                   10950:     }
                   10951:     ungetc(c,ficpar);
                   10952:     
                   10953:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10954:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10955:     for(i=1; i <=nlstate; i++){
1.234     brouard  10956:       j=0;
1.126     brouard  10957:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10958:        if(jj==i) continue;
                   10959:        j++;
                   10960:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10961:        if ((i1 != i) || (j1 != jj)){
                   10962:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10963: It might be a problem of design; if ncovcol and the model are correct\n \
                   10964: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10965:          exit(1);
                   10966:        }
                   10967:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10968:        if(mle==1)
                   10969:          printf("%1d%1d",i,jj);
                   10970:        fprintf(ficlog,"%1d%1d",i,jj);
                   10971:        for(k=1; k<=ncovmodel;k++){
                   10972:          fscanf(ficpar," %lf",&param[i][j][k]);
                   10973:          if(mle==1){
                   10974:            printf(" %lf",param[i][j][k]);
                   10975:            fprintf(ficlog," %lf",param[i][j][k]);
                   10976:          }
                   10977:          else
                   10978:            fprintf(ficlog," %lf",param[i][j][k]);
                   10979:          fprintf(ficparo," %lf",param[i][j][k]);
                   10980:        }
                   10981:        fscanf(ficpar,"\n");
                   10982:        numlinepar++;
                   10983:        if(mle==1)
                   10984:          printf("\n");
                   10985:        fprintf(ficlog,"\n");
                   10986:        fprintf(ficparo,"\n");
1.126     brouard  10987:       }
                   10988:     }  
                   10989:     fflush(ficlog);
1.234     brouard  10990:     
1.251     brouard  10991:     /* Reads parameters values */
1.126     brouard  10992:     p=param[1][1];
1.251     brouard  10993:     pstart=paramstart[1][1];
1.126     brouard  10994:     
                   10995:     /* Reads comments: lines beginning with '#' */
                   10996:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10997:       ungetc(c,ficpar);
                   10998:       fgets(line, MAXLINE, ficpar);
                   10999:       numlinepar++;
1.141     brouard  11000:       fputs(line,stdout);
1.126     brouard  11001:       fputs(line,ficparo);
                   11002:       fputs(line,ficlog);
                   11003:     }
                   11004:     ungetc(c,ficpar);
                   11005: 
                   11006:     for(i=1; i <=nlstate; i++){
                   11007:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11008:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11009:        if ( (i1-i) * (j1-j) != 0){
                   11010:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11011:          exit(1);
                   11012:        }
                   11013:        printf("%1d%1d",i,j);
                   11014:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11015:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11016:        for(k=1; k<=ncovmodel;k++){
                   11017:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11018:          printf(" %le",delti3[i][j][k]);
                   11019:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11020:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11021:        }
                   11022:        fscanf(ficpar,"\n");
                   11023:        numlinepar++;
                   11024:        printf("\n");
                   11025:        fprintf(ficparo,"\n");
                   11026:        fprintf(ficlog,"\n");
1.126     brouard  11027:       }
                   11028:     }
                   11029:     fflush(ficlog);
1.234     brouard  11030:     
1.145     brouard  11031:     /* Reads covariance matrix */
1.126     brouard  11032:     delti=delti3[1][1];
1.220     brouard  11033:                
                   11034:                
1.126     brouard  11035:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11036:                
1.126     brouard  11037:     /* Reads comments: lines beginning with '#' */
                   11038:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11039:       ungetc(c,ficpar);
                   11040:       fgets(line, MAXLINE, ficpar);
                   11041:       numlinepar++;
1.141     brouard  11042:       fputs(line,stdout);
1.126     brouard  11043:       fputs(line,ficparo);
                   11044:       fputs(line,ficlog);
                   11045:     }
                   11046:     ungetc(c,ficpar);
1.220     brouard  11047:                
1.126     brouard  11048:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11049:     hess=matrix(1,npar,1,npar);
1.131     brouard  11050:     for(i=1; i <=npar; i++)
                   11051:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11052:                
1.194     brouard  11053:     /* Scans npar lines */
1.126     brouard  11054:     for(i=1; i <=npar; i++){
1.226     brouard  11055:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11056:       if(count != 3){
1.226     brouard  11057:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11058: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11059: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11060:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11061: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11062: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11063:        exit(1);
1.220     brouard  11064:       }else{
1.226     brouard  11065:        if(mle==1)
                   11066:          printf("%1d%1d%d",i1,j1,jk);
                   11067:       }
                   11068:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11069:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11070:       for(j=1; j <=i; j++){
1.226     brouard  11071:        fscanf(ficpar," %le",&matcov[i][j]);
                   11072:        if(mle==1){
                   11073:          printf(" %.5le",matcov[i][j]);
                   11074:        }
                   11075:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11076:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11077:       }
                   11078:       fscanf(ficpar,"\n");
                   11079:       numlinepar++;
                   11080:       if(mle==1)
1.220     brouard  11081:                                printf("\n");
1.126     brouard  11082:       fprintf(ficlog,"\n");
                   11083:       fprintf(ficparo,"\n");
                   11084:     }
1.194     brouard  11085:     /* End of read covariance matrix npar lines */
1.126     brouard  11086:     for(i=1; i <=npar; i++)
                   11087:       for(j=i+1;j<=npar;j++)
1.226     brouard  11088:        matcov[i][j]=matcov[j][i];
1.126     brouard  11089:     
                   11090:     if(mle==1)
                   11091:       printf("\n");
                   11092:     fprintf(ficlog,"\n");
                   11093:     
                   11094:     fflush(ficlog);
                   11095:     
                   11096:     /*-------- Rewriting parameter file ----------*/
                   11097:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   11098:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   11099:     strcat(rfileres,".");    /* */
                   11100:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11101:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  11102:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11103:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  11104:     }
                   11105:     fprintf(ficres,"#%s\n",version);
                   11106:   }    /* End of mle != -3 */
1.218     brouard  11107:   
1.186     brouard  11108:   /*  Main data
                   11109:    */
1.126     brouard  11110:   n= lastobs;
                   11111:   num=lvector(1,n);
                   11112:   moisnais=vector(1,n);
                   11113:   annais=vector(1,n);
                   11114:   moisdc=vector(1,n);
                   11115:   andc=vector(1,n);
1.220     brouard  11116:   weight=vector(1,n);
1.126     brouard  11117:   agedc=vector(1,n);
                   11118:   cod=ivector(1,n);
1.220     brouard  11119:   for(i=1;i<=n;i++){
1.234     brouard  11120:     num[i]=0;
                   11121:     moisnais[i]=0;
                   11122:     annais[i]=0;
                   11123:     moisdc[i]=0;
                   11124:     andc[i]=0;
                   11125:     agedc[i]=0;
                   11126:     cod[i]=0;
                   11127:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11128:   }
1.126     brouard  11129:   mint=matrix(1,maxwav,1,n);
                   11130:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11131:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11132:   tab=ivector(1,NCOVMAX);
1.144     brouard  11133:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11134:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11135: 
1.136     brouard  11136:   /* Reads data from file datafile */
                   11137:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11138:     goto end;
                   11139: 
                   11140:   /* Calculation of the number of parameters from char model */
1.234     brouard  11141:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11142:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11143:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11144:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11145:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11146:   */
                   11147:   
                   11148:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11149:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11150:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11151:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11152:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11153:   TvarF=ivector(1,NCOVMAX); /*  */
                   11154:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11155:   TvarV=ivector(1,NCOVMAX); /*  */
                   11156:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11157:   TvarA=ivector(1,NCOVMAX); /*  */
                   11158:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11159:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11160:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11161:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11162:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11163:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11164:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11165:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11166:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11167: 
1.230     brouard  11168:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11169:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11170:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11171:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11172:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11173:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11174:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11175:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11176:   */
                   11177:   /* For model-covariate k tells which data-covariate to use but
                   11178:     because this model-covariate is a construction we invent a new column
                   11179:     ncovcol + k1
                   11180:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11181:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11182:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11183:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11184:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11185:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11186:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11187:   */
1.145     brouard  11188:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11189:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11190:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11191:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11192:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11193:                         4 covariates (3 plus signs)
                   11194:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11195:                      */  
1.230     brouard  11196:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11197:                                * individual dummy, fixed or varying:
                   11198:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11199:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11200:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11201:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11202:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11203:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11204:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11205:                                * individual quantitative, fixed or varying:
                   11206:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11207:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11208:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11209: /* Main decodemodel */
                   11210: 
1.187     brouard  11211: 
1.223     brouard  11212:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11213:     goto end;
                   11214: 
1.137     brouard  11215:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11216:     nbwarn++;
                   11217:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11218:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11219:   }
1.136     brouard  11220:     /*  if(mle==1){*/
1.137     brouard  11221:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11222:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11223:   }
                   11224: 
                   11225:     /*-calculation of age at interview from date of interview and age at death -*/
                   11226:   agev=matrix(1,maxwav,1,imx);
                   11227: 
                   11228:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11229:     goto end;
                   11230: 
1.126     brouard  11231: 
1.136     brouard  11232:   agegomp=(int)agemin;
                   11233:   free_vector(moisnais,1,n);
                   11234:   free_vector(annais,1,n);
1.126     brouard  11235:   /* free_matrix(mint,1,maxwav,1,n);
                   11236:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11237:   /* free_vector(moisdc,1,n); */
                   11238:   /* free_vector(andc,1,n); */
1.145     brouard  11239:   /* */
                   11240:   
1.126     brouard  11241:   wav=ivector(1,imx);
1.214     brouard  11242:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11243:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11244:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11245:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11246:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11247:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11248:    
                   11249:   /* Concatenates waves */
1.214     brouard  11250:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11251:      Death is a valid wave (if date is known).
                   11252:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11253:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11254:      and mw[mi+1][i]. dh depends on stepm.
                   11255:   */
                   11256: 
1.126     brouard  11257:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11258:   /* Concatenates waves */
1.145     brouard  11259:  
1.215     brouard  11260:   free_vector(moisdc,1,n);
                   11261:   free_vector(andc,1,n);
                   11262: 
1.126     brouard  11263:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11264:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11265:   ncodemax[1]=1;
1.145     brouard  11266:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11267:   cptcoveff=0;
1.220     brouard  11268:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11269:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11270:   }
                   11271:   
                   11272:   ncovcombmax=pow(2,cptcoveff);
                   11273:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11274:   for(i=1;i<ncovcombmax;i++)
                   11275:     invalidvarcomb[i]=0;
                   11276:   
1.211     brouard  11277:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11278:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11279:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11280:   
1.200     brouard  11281:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11282:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11283:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11284:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11285:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11286:    * (currently 0 or 1) in the data.
                   11287:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11288:    * corresponding modality (h,j).
                   11289:    */
                   11290: 
1.145     brouard  11291:   h=0;
                   11292:   /*if (cptcovn > 0) */
1.126     brouard  11293:   m=pow(2,cptcoveff);
                   11294:  
1.144     brouard  11295:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11296:           * For k=4 covariates, h goes from 1 to m=2**k
                   11297:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11298:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11299:           *     h\k   1     2     3     4
1.143     brouard  11300:           *______________________________  
                   11301:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11302:           *     2     2     1     1     1
                   11303:           *     3 i=2 1     2     1     1
                   11304:           *     4     2     2     1     1
                   11305:           *     5 i=3 1 i=2 1     2     1
                   11306:           *     6     2     1     2     1
                   11307:           *     7 i=4 1     2     2     1
                   11308:           *     8     2     2     2     1
1.197     brouard  11309:           *     9 i=5 1 i=3 1 i=2 1     2
                   11310:           *    10     2     1     1     2
                   11311:           *    11 i=6 1     2     1     2
                   11312:           *    12     2     2     1     2
                   11313:           *    13 i=7 1 i=4 1     2     2    
                   11314:           *    14     2     1     2     2
                   11315:           *    15 i=8 1     2     2     2
                   11316:           *    16     2     2     2     2
1.143     brouard  11317:           */
1.212     brouard  11318:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11319:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11320:      * and the value of each covariate?
                   11321:      * V1=1, V2=1, V3=2, V4=1 ?
                   11322:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11323:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11324:      * In order to get the real value in the data, we use nbcode
                   11325:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11326:      * We are keeping this crazy system in order to be able (in the future?) 
                   11327:      * to have more than 2 values (0 or 1) for a covariate.
                   11328:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11329:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11330:      *              bbbbbbbb
                   11331:      *              76543210     
                   11332:      *   h-1        00000101 (6-1=5)
1.219     brouard  11333:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11334:      *           &
                   11335:      *     1        00000001 (1)
1.219     brouard  11336:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11337:      *          +1= 00000001 =1 
1.211     brouard  11338:      *
                   11339:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11340:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11341:      *    >>k'            11
                   11342:      *          &   00000001
                   11343:      *            = 00000001
                   11344:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11345:      * Reverse h=6 and m=16?
                   11346:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11347:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11348:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11349:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11350:      * V3=decodtabm(14,3,2**4)=2
                   11351:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11352:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11353:      *          &1 000000001
                   11354:      *           = 000000001
                   11355:      *         +1= 000000010 =2
                   11356:      *                  2211
                   11357:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11358:      *                  V3=2
1.220     brouard  11359:                 * codtabm and decodtabm are identical
1.211     brouard  11360:      */
                   11361: 
1.145     brouard  11362: 
                   11363:  free_ivector(Ndum,-1,NCOVMAX);
                   11364: 
                   11365: 
1.126     brouard  11366:     
1.186     brouard  11367:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11368:   strcpy(optionfilegnuplot,optionfilefiname);
                   11369:   if(mle==-3)
1.201     brouard  11370:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11371:   strcat(optionfilegnuplot,".gp");
                   11372: 
                   11373:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11374:     printf("Problem with file %s",optionfilegnuplot);
                   11375:   }
                   11376:   else{
1.204     brouard  11377:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11378:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11379:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11380:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11381:   }
                   11382:   /*  fclose(ficgp);*/
1.186     brouard  11383: 
                   11384: 
                   11385:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11386: 
                   11387:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11388:   if(mle==-3)
1.201     brouard  11389:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11390:   strcat(optionfilehtm,".htm");
                   11391:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11392:     printf("Problem with %s \n",optionfilehtm);
                   11393:     exit(0);
1.126     brouard  11394:   }
                   11395: 
                   11396:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11397:   strcat(optionfilehtmcov,"-cov.htm");
                   11398:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11399:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11400:   }
                   11401:   else{
                   11402:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11403: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11404: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11405:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11406:   }
                   11407: 
1.213     brouard  11408:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11409: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11410: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11411: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11412: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11413: \n\
                   11414: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11415:  <ul><li><h4>Parameter files</h4>\n\
                   11416:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11417:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11418:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11419:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11420:  - Date and time at start: %s</ul>\n",\
                   11421:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11422:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11423:          fileres,fileres,\
                   11424:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11425:   fflush(fichtm);
                   11426: 
                   11427:   strcpy(pathr,path);
                   11428:   strcat(pathr,optionfilefiname);
1.184     brouard  11429: #ifdef WIN32
                   11430:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11431: #else
1.126     brouard  11432:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11433: #endif
                   11434:          
1.126     brouard  11435:   
1.220     brouard  11436:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11437:                 and for any valid combination of covariates
1.126     brouard  11438:      and prints on file fileres'p'. */
1.251     brouard  11439:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11440:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11441: 
                   11442:   fprintf(fichtm,"\n");
                   11443:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   11444: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11445: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   11446:          imx,agemin,agemax,jmin,jmax,jmean);
                   11447:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11448:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11449:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11450:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11451:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11452: 
1.126     brouard  11453:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11454:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11455:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11456: 
                   11457:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11458:   /* For mortality only */
1.126     brouard  11459:   if (mle==-3){
1.136     brouard  11460:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11461:     for(i=1;i<=NDIM;i++)
                   11462:       for(j=1;j<=NDIM;j++)
                   11463:        ximort[i][j]=0.;
1.186     brouard  11464:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11465:     cens=ivector(1,n);
                   11466:     ageexmed=vector(1,n);
                   11467:     agecens=vector(1,n);
                   11468:     dcwave=ivector(1,n);
1.223     brouard  11469:                
1.126     brouard  11470:     for (i=1; i<=imx; i++){
                   11471:       dcwave[i]=-1;
                   11472:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11473:        if (s[m][i]>nlstate) {
                   11474:          dcwave[i]=m;
                   11475:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11476:          break;
                   11477:        }
1.126     brouard  11478:     }
1.226     brouard  11479:     
1.126     brouard  11480:     for (i=1; i<=imx; i++) {
                   11481:       if (wav[i]>0){
1.226     brouard  11482:        ageexmed[i]=agev[mw[1][i]][i];
                   11483:        j=wav[i];
                   11484:        agecens[i]=1.; 
                   11485:        
                   11486:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11487:          agecens[i]=agev[mw[j][i]][i];
                   11488:          cens[i]= 1;
                   11489:        }else if (ageexmed[i]< 1) 
                   11490:          cens[i]= -1;
                   11491:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11492:          cens[i]=0 ;
1.126     brouard  11493:       }
                   11494:       else cens[i]=-1;
                   11495:     }
                   11496:     
                   11497:     for (i=1;i<=NDIM;i++) {
                   11498:       for (j=1;j<=NDIM;j++)
1.226     brouard  11499:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11500:     }
                   11501:     
1.145     brouard  11502:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11503:     /*printf("%lf %lf", p[1], p[2]);*/
                   11504:     
                   11505:     
1.136     brouard  11506: #ifdef GSL
                   11507:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11508: #else
1.126     brouard  11509:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11510: #endif
1.201     brouard  11511:     strcpy(filerespow,"POW-MORT_"); 
                   11512:     strcat(filerespow,fileresu);
1.126     brouard  11513:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11514:       printf("Problem with resultfile: %s\n", filerespow);
                   11515:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11516:     }
1.136     brouard  11517: #ifdef GSL
                   11518:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11519: #else
1.126     brouard  11520:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11521: #endif
1.126     brouard  11522:     /*  for (i=1;i<=nlstate;i++)
                   11523:        for(j=1;j<=nlstate+ndeath;j++)
                   11524:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11525:     */
                   11526:     fprintf(ficrespow,"\n");
1.136     brouard  11527: #ifdef GSL
                   11528:     /* gsl starts here */ 
                   11529:     T = gsl_multimin_fminimizer_nmsimplex;
                   11530:     gsl_multimin_fminimizer *sfm = NULL;
                   11531:     gsl_vector *ss, *x;
                   11532:     gsl_multimin_function minex_func;
                   11533: 
                   11534:     /* Initial vertex size vector */
                   11535:     ss = gsl_vector_alloc (NDIM);
                   11536:     
                   11537:     if (ss == NULL){
                   11538:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11539:     }
                   11540:     /* Set all step sizes to 1 */
                   11541:     gsl_vector_set_all (ss, 0.001);
                   11542: 
                   11543:     /* Starting point */
1.126     brouard  11544:     
1.136     brouard  11545:     x = gsl_vector_alloc (NDIM);
                   11546:     
                   11547:     if (x == NULL){
                   11548:       gsl_vector_free(ss);
                   11549:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11550:     }
                   11551:   
                   11552:     /* Initialize method and iterate */
                   11553:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11554:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11555:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11556:     gsl_vector_set(x, 0, p[1]);
                   11557:     gsl_vector_set(x, 1, p[2]);
                   11558: 
                   11559:     minex_func.f = &gompertz_f;
                   11560:     minex_func.n = NDIM;
                   11561:     minex_func.params = (void *)&p; /* ??? */
                   11562:     
                   11563:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11564:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11565:     
                   11566:     printf("Iterations beginning .....\n\n");
                   11567:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11568: 
                   11569:     iteri=0;
                   11570:     while (rval == GSL_CONTINUE){
                   11571:       iteri++;
                   11572:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11573:       
                   11574:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11575:       fflush(0);
                   11576:       
                   11577:       if (status) 
                   11578:         break;
                   11579:       
                   11580:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11581:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11582:       
                   11583:       if (rval == GSL_SUCCESS)
                   11584:         printf ("converged to a local maximum at\n");
                   11585:       
                   11586:       printf("%5d ", iteri);
                   11587:       for (it = 0; it < NDIM; it++){
                   11588:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11589:       }
                   11590:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11591:     }
                   11592:     
                   11593:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11594:     
                   11595:     gsl_vector_free(x); /* initial values */
                   11596:     gsl_vector_free(ss); /* inital step size */
                   11597:     for (it=0; it<NDIM; it++){
                   11598:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11599:       fprintf(ficrespow," %.12lf", p[it]);
                   11600:     }
                   11601:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11602: #endif
                   11603: #ifdef POWELL
                   11604:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11605: #endif  
1.126     brouard  11606:     fclose(ficrespow);
                   11607:     
1.203     brouard  11608:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11609: 
                   11610:     for(i=1; i <=NDIM; i++)
                   11611:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11612:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11613:     
                   11614:     printf("\nCovariance matrix\n ");
1.203     brouard  11615:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11616:     for(i=1; i <=NDIM; i++) {
                   11617:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11618:                                printf("%f ",matcov[i][j]);
                   11619:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11620:       }
1.203     brouard  11621:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11622:     }
                   11623:     
                   11624:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11625:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11626:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11627:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11628:     }
1.126     brouard  11629:     lsurv=vector(1,AGESUP);
                   11630:     lpop=vector(1,AGESUP);
                   11631:     tpop=vector(1,AGESUP);
                   11632:     lsurv[agegomp]=100000;
                   11633:     
                   11634:     for (k=agegomp;k<=AGESUP;k++) {
                   11635:       agemortsup=k;
                   11636:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11637:     }
                   11638:     
                   11639:     for (k=agegomp;k<agemortsup;k++)
                   11640:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11641:     
                   11642:     for (k=agegomp;k<agemortsup;k++){
                   11643:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11644:       sumlpop=sumlpop+lpop[k];
                   11645:     }
                   11646:     
                   11647:     tpop[agegomp]=sumlpop;
                   11648:     for (k=agegomp;k<(agemortsup-3);k++){
                   11649:       /*  tpop[k+1]=2;*/
                   11650:       tpop[k+1]=tpop[k]-lpop[k];
                   11651:     }
                   11652:     
                   11653:     
                   11654:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11655:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11656:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11657:     
                   11658:     
                   11659:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11660:                ageminpar=50;
                   11661:                agemaxpar=100;
1.194     brouard  11662:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11663:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11664: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11665: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11666:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11667: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11668: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11669:     }else{
                   11670:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11671:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11672:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11673:                }
1.201     brouard  11674:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11675:                     stepm, weightopt,\
                   11676:                     model,imx,p,matcov,agemortsup);
                   11677:     
                   11678:     free_vector(lsurv,1,AGESUP);
                   11679:     free_vector(lpop,1,AGESUP);
                   11680:     free_vector(tpop,1,AGESUP);
1.220     brouard  11681:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11682:     free_ivector(cens,1,n);
                   11683:     free_vector(agecens,1,n);
                   11684:     free_ivector(dcwave,1,n);
1.220     brouard  11685: #ifdef GSL
1.136     brouard  11686: #endif
1.186     brouard  11687:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11688:   /* Standard  */
                   11689:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11690:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11691:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11692:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11693:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11694:     for (k=1; k<=npar;k++)
                   11695:       printf(" %d %8.5f",k,p[k]);
                   11696:     printf("\n");
1.205     brouard  11697:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11698:       /* mlikeli uses func not funcone */
1.247     brouard  11699:       /* for(i=1;i<nlstate;i++){ */
                   11700:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11701:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11702:       /* } */
1.205     brouard  11703:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11704:     }
                   11705:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11706:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11707:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11708:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11709:     }
                   11710:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11711:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11712:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11713:     for (k=1; k<=npar;k++)
                   11714:       printf(" %d %8.5f",k,p[k]);
                   11715:     printf("\n");
                   11716:     
                   11717:     /*--------- results files --------------*/
1.224     brouard  11718:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  11719:     
                   11720:     
                   11721:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11722:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11723:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11724:     for(i=1,jk=1; i <=nlstate; i++){
                   11725:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11726:        if (k != i) {
                   11727:          printf("%d%d ",i,k);
                   11728:          fprintf(ficlog,"%d%d ",i,k);
                   11729:          fprintf(ficres,"%1d%1d ",i,k);
                   11730:          for(j=1; j <=ncovmodel; j++){
                   11731:            printf("%12.7f ",p[jk]);
                   11732:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11733:            fprintf(ficres,"%12.7f ",p[jk]);
                   11734:            jk++; 
                   11735:          }
                   11736:          printf("\n");
                   11737:          fprintf(ficlog,"\n");
                   11738:          fprintf(ficres,"\n");
                   11739:        }
1.126     brouard  11740:       }
                   11741:     }
1.203     brouard  11742:     if(mle != 0){
                   11743:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11744:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11745:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11746:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11747:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11748:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11749:        for(k=1; k <=(nlstate+ndeath); k++){
                   11750:          if (k != i) {
                   11751:            printf("%d%d ",i,k);
                   11752:            fprintf(ficlog,"%d%d ",i,k);
                   11753:            for(j=1; j <=ncovmodel; j++){
                   11754:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11755:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11756:              jk++; 
                   11757:            }
                   11758:            printf("\n");
                   11759:            fprintf(ficlog,"\n");
                   11760:          }
                   11761:        }
1.193     brouard  11762:       }
1.203     brouard  11763:     } /* end of hesscov and Wald tests */
1.225     brouard  11764:     
1.203     brouard  11765:     /*  */
1.126     brouard  11766:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11767:     printf("# Scales (for hessian or gradient estimation)\n");
                   11768:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11769:     for(i=1,jk=1; i <=nlstate; i++){
                   11770:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11771:        if (j!=i) {
                   11772:          fprintf(ficres,"%1d%1d",i,j);
                   11773:          printf("%1d%1d",i,j);
                   11774:          fprintf(ficlog,"%1d%1d",i,j);
                   11775:          for(k=1; k<=ncovmodel;k++){
                   11776:            printf(" %.5e",delti[jk]);
                   11777:            fprintf(ficlog," %.5e",delti[jk]);
                   11778:            fprintf(ficres," %.5e",delti[jk]);
                   11779:            jk++;
                   11780:          }
                   11781:          printf("\n");
                   11782:          fprintf(ficlog,"\n");
                   11783:          fprintf(ficres,"\n");
                   11784:        }
1.126     brouard  11785:       }
                   11786:     }
                   11787:     
                   11788:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11789:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11790:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11791:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11792:     /* # 121 Var(a12)\n\ */
                   11793:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11794:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11795:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11796:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11797:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11798:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11799:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11800:     
                   11801:     
                   11802:     /* Just to have a covariance matrix which will be more understandable
                   11803:        even is we still don't want to manage dictionary of variables
                   11804:     */
                   11805:     for(itimes=1;itimes<=2;itimes++){
                   11806:       jj=0;
                   11807:       for(i=1; i <=nlstate; i++){
1.225     brouard  11808:        for(j=1; j <=nlstate+ndeath; j++){
                   11809:          if(j==i) continue;
                   11810:          for(k=1; k<=ncovmodel;k++){
                   11811:            jj++;
                   11812:            ca[0]= k+'a'-1;ca[1]='\0';
                   11813:            if(itimes==1){
                   11814:              if(mle>=1)
                   11815:                printf("#%1d%1d%d",i,j,k);
                   11816:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11817:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11818:            }else{
                   11819:              if(mle>=1)
                   11820:                printf("%1d%1d%d",i,j,k);
                   11821:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11822:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11823:            }
                   11824:            ll=0;
                   11825:            for(li=1;li <=nlstate; li++){
                   11826:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11827:                if(lj==li) continue;
                   11828:                for(lk=1;lk<=ncovmodel;lk++){
                   11829:                  ll++;
                   11830:                  if(ll<=jj){
                   11831:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11832:                    if(ll<jj){
                   11833:                      if(itimes==1){
                   11834:                        if(mle>=1)
                   11835:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11836:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11837:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11838:                      }else{
                   11839:                        if(mle>=1)
                   11840:                          printf(" %.5e",matcov[jj][ll]); 
                   11841:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11842:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11843:                      }
                   11844:                    }else{
                   11845:                      if(itimes==1){
                   11846:                        if(mle>=1)
                   11847:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11848:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11849:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11850:                      }else{
                   11851:                        if(mle>=1)
                   11852:                          printf(" %.7e",matcov[jj][ll]); 
                   11853:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11854:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11855:                      }
                   11856:                    }
                   11857:                  }
                   11858:                } /* end lk */
                   11859:              } /* end lj */
                   11860:            } /* end li */
                   11861:            if(mle>=1)
                   11862:              printf("\n");
                   11863:            fprintf(ficlog,"\n");
                   11864:            fprintf(ficres,"\n");
                   11865:            numlinepar++;
                   11866:          } /* end k*/
                   11867:        } /*end j */
1.126     brouard  11868:       } /* end i */
                   11869:     } /* end itimes */
                   11870:     
                   11871:     fflush(ficlog);
                   11872:     fflush(ficres);
1.225     brouard  11873:     while(fgets(line, MAXLINE, ficpar)) {
                   11874:       /* If line starts with a # it is a comment */
                   11875:       if (line[0] == '#') {
                   11876:        numlinepar++;
                   11877:        fputs(line,stdout);
                   11878:        fputs(line,ficparo);
                   11879:        fputs(line,ficlog);
                   11880:        continue;
                   11881:       }else
                   11882:        break;
                   11883:     }
                   11884:     
1.209     brouard  11885:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11886:     /*   ungetc(c,ficpar); */
                   11887:     /*   fgets(line, MAXLINE, ficpar); */
                   11888:     /*   fputs(line,stdout); */
                   11889:     /*   fputs(line,ficparo); */
                   11890:     /* } */
                   11891:     /* ungetc(c,ficpar); */
1.126     brouard  11892:     
                   11893:     estepm=0;
1.209     brouard  11894:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11895:       
                   11896:       if (num_filled != 6) {
                   11897:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11898:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11899:        goto end;
                   11900:       }
                   11901:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11902:     }
                   11903:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11904:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11905:     
1.209     brouard  11906:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11907:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11908:     if (fage <= 2) {
                   11909:       bage = ageminpar;
                   11910:       fage = agemaxpar;
                   11911:     }
                   11912:     
                   11913:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11914:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11915:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11916:                
1.186     brouard  11917:     /* Other stuffs, more or less useful */    
1.254     brouard  11918:     while(fgets(line, MAXLINE, ficpar)) {
                   11919:       /* If line starts with a # it is a comment */
                   11920:       if (line[0] == '#') {
                   11921:        numlinepar++;
                   11922:        fputs(line,stdout);
                   11923:        fputs(line,ficparo);
                   11924:        fputs(line,ficlog);
                   11925:        continue;
                   11926:       }else
                   11927:        break;
                   11928:     }
                   11929: 
                   11930:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11931:       
                   11932:       if (num_filled != 7) {
                   11933:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11934:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11935:        goto end;
                   11936:       }
                   11937:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11938:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11939:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11940:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11941:     }
1.254     brouard  11942: 
                   11943:     while(fgets(line, MAXLINE, ficpar)) {
                   11944:       /* If line starts with a # it is a comment */
                   11945:       if (line[0] == '#') {
                   11946:        numlinepar++;
                   11947:        fputs(line,stdout);
                   11948:        fputs(line,ficparo);
                   11949:        fputs(line,ficlog);
                   11950:        continue;
                   11951:       }else
                   11952:        break;
1.126     brouard  11953:     }
                   11954:     
                   11955:     
                   11956:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11957:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11958:     
1.254     brouard  11959:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11960:       if (num_filled != 1) {
                   11961:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11962:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11963:        goto end;
                   11964:       }
                   11965:       printf("pop_based=%d\n",popbased);
                   11966:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11967:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11968:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11969:     }
                   11970:      
1.258     brouard  11971:     /* Results */
                   11972:     nresult=0;
                   11973:     do{
                   11974:       if(!fgets(line, MAXLINE, ficpar)){
                   11975:        endishere=1;
                   11976:        parameterline=14;
                   11977:       }else if (line[0] == '#') {
                   11978:        /* If line starts with a # it is a comment */
1.254     brouard  11979:        numlinepar++;
                   11980:        fputs(line,stdout);
                   11981:        fputs(line,ficparo);
                   11982:        fputs(line,ficlog);
                   11983:        continue;
1.258     brouard  11984:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   11985:        parameterline=11;
                   11986:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   11987:        parameterline=12;
                   11988:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   11989:        parameterline=13;
                   11990:       else{
                   11991:        parameterline=14;
1.254     brouard  11992:       }
1.258     brouard  11993:       switch (parameterline){ 
                   11994:       case 11:
                   11995:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   11996:          if (num_filled != 8) {
                   11997:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11998:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11999:            goto end;
                   12000:          }
                   12001:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12002:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12003:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12004:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12005:          /* day and month of proj2 are not used but only year anproj2.*/
                   12006:        }
1.254     brouard  12007:        break;
1.258     brouard  12008:       case 12:
                   12009:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12010:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12011:          if (num_filled != 8) {
1.262     brouard  12012:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12013:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12014:            goto end;
                   12015:          }
                   12016:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12017:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12018:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12019:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12020:          /* day and month of proj2 are not used but only year anproj2.*/
                   12021:        }
1.230     brouard  12022:        break;
1.258     brouard  12023:       case 13:
                   12024:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12025:          if (num_filled == 0){
                   12026:            resultline[0]='\0';
                   12027:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12028:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12029:            break;
                   12030:          } else if (num_filled != 1){
                   12031:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12032:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12033:          }
                   12034:          nresult++; /* Sum of resultlines */
                   12035:          printf("Result %d: result=%s\n",nresult, resultline);
                   12036:          if(nresult > MAXRESULTLINES){
                   12037:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12038:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12039:            goto end;
                   12040:          }
                   12041:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12042:          fprintf(ficparo,"result: %s\n",resultline);
                   12043:          fprintf(ficres,"result: %s\n",resultline);
                   12044:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12045:          break;
1.258     brouard  12046:        case 14: 
1.259     brouard  12047:          if(ncovmodel >2 && nresult==0 ){
                   12048:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12049:            goto end;
                   12050:          }
1.259     brouard  12051:          break;
1.258     brouard  12052:        default:
                   12053:          nresult=1;
                   12054:          decoderesult(".",nresult ); /* No covariate */
                   12055:        }
                   12056:       } /* End switch parameterline */
                   12057:     }while(endishere==0); /* End do */
1.126     brouard  12058:     
1.230     brouard  12059:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12060:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12061:     
                   12062:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12063:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12064:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12065: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12066: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12067:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12068: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12069: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12070:     }else{
1.268     brouard  12071:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1);
1.220     brouard  12072:     }
                   12073:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12074:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.225     brouard  12075:                 jprev1,mprev1,anprev1,dateprev1,jprev2,mprev2,anprev2,dateprev2);
1.220     brouard  12076:                
1.225     brouard  12077:     /*------------ free_vector  -------------*/
                   12078:     /*  chdir(path); */
1.220     brouard  12079:                
1.215     brouard  12080:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12081:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12082:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12083:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12084:     free_lvector(num,1,n);
                   12085:     free_vector(agedc,1,n);
                   12086:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12087:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12088:     fclose(ficparo);
                   12089:     fclose(ficres);
1.220     brouard  12090:                
                   12091:                
1.186     brouard  12092:     /* Other results (useful)*/
1.220     brouard  12093:                
                   12094:                
1.126     brouard  12095:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12096:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12097:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12098:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12099:     fclose(ficrespl);
                   12100: 
                   12101:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12102:     /*#include "hpijx.h"*/
                   12103:     hPijx(p, bage, fage);
1.145     brouard  12104:     fclose(ficrespij);
1.227     brouard  12105:     
1.220     brouard  12106:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12107:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12108:     k=1;
1.126     brouard  12109:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12110:     
1.269   ! brouard  12111:     /* Prevalence for each covariate combination in probs[age][status][cov] */
        !          12112:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
        !          12113:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12114:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12115:        for(k=1;k<=ncovcombmax;k++)
                   12116:          probs[i][j][k]=0.;
1.269   ! brouard  12117:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
        !          12118:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12119:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269   ! brouard  12120:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
        !          12121:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12122:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12123:          for(k=1;k<=ncovcombmax;k++)
                   12124:            mobaverages[i][j][k]=0.;
1.219     brouard  12125:       mobaverage=mobaverages;
                   12126:       if (mobilav!=0) {
1.235     brouard  12127:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12128:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12129:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12130:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12131:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12132:        }
1.269   ! brouard  12133:       } else if (mobilavproj !=0) {
1.235     brouard  12134:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12135:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12136:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12137:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12138:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12139:        }
1.269   ! brouard  12140:       }else{
        !          12141:        printf("Internal error moving average\n");
        !          12142:        fflush(stdout);
        !          12143:        exit(1);
1.219     brouard  12144:       }
                   12145:     }/* end if moving average */
1.227     brouard  12146:     
1.126     brouard  12147:     /*---------- Forecasting ------------------*/
                   12148:     if(prevfcast==1){
                   12149:       /*    if(stepm ==1){*/
1.269   ! brouard  12150:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12151:     }
1.269   ! brouard  12152: 
        !          12153:     /* Backcasting */
1.217     brouard  12154:     if(backcast==1){
1.219     brouard  12155:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12156:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12157:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12158: 
                   12159:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12160: 
                   12161:       bprlim=matrix(1,nlstate,1,nlstate);
1.269   ! brouard  12162: 
1.219     brouard  12163:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12164:       fclose(ficresplb);
                   12165: 
1.222     brouard  12166:       hBijx(p, bage, fage, mobaverage);
                   12167:       fclose(ficrespijb);
1.219     brouard  12168: 
1.269   ! brouard  12169:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
        !          12170:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
        !          12171:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12172: 
                   12173:       
1.269   ! brouard  12174:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12175:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12176:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12177:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269   ! brouard  12178:     }    /* end  Backcasting */
1.268     brouard  12179:  
1.186     brouard  12180:  
                   12181:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12182: 
1.215     brouard  12183:     free_ivector(wav,1,imx);
                   12184:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12185:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12186:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12187:                
                   12188:                
1.127     brouard  12189:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12190:                
1.201     brouard  12191:     strcpy(filerese,"E_");
                   12192:     strcat(filerese,fileresu);
1.126     brouard  12193:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12194:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12195:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12196:     }
1.208     brouard  12197:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12198:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12199: 
                   12200:     pstamp(ficreseij);
1.219     brouard  12201:                
1.235     brouard  12202:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12203:     if (cptcovn < 1){i1=1;}
                   12204:     
                   12205:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12206:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12207:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12208:        continue;
1.219     brouard  12209:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12210:       printf("\n#****** ");
1.225     brouard  12211:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12212:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12213:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12214:       }
                   12215:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12216:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12217:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12218:       }
                   12219:       fprintf(ficreseij,"******\n");
1.235     brouard  12220:       printf("******\n");
1.219     brouard  12221:       
                   12222:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12223:       oldm=oldms;savm=savms;
1.235     brouard  12224:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12225:       
1.219     brouard  12226:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12227:     }
                   12228:     fclose(ficreseij);
1.208     brouard  12229:     printf("done evsij\n");fflush(stdout);
                   12230:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269   ! brouard  12231: 
1.218     brouard  12232:                
1.227     brouard  12233:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12234:                
1.201     brouard  12235:     strcpy(filerest,"T_");
                   12236:     strcat(filerest,fileresu);
1.127     brouard  12237:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12238:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12239:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12240:     }
1.208     brouard  12241:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12242:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12243:     strcpy(fileresstde,"STDE_");
                   12244:     strcat(fileresstde,fileresu);
1.126     brouard  12245:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12246:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12247:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12248:     }
1.227     brouard  12249:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12250:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12251: 
1.201     brouard  12252:     strcpy(filerescve,"CVE_");
                   12253:     strcat(filerescve,fileresu);
1.126     brouard  12254:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12255:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12256:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12257:     }
1.227     brouard  12258:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12259:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12260: 
1.201     brouard  12261:     strcpy(fileresv,"V_");
                   12262:     strcat(fileresv,fileresu);
1.126     brouard  12263:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12264:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12265:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12266:     }
1.227     brouard  12267:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12268:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12269: 
1.235     brouard  12270:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12271:     if (cptcovn < 1){i1=1;}
                   12272:     
                   12273:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12274:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12275:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12276:        continue;
1.242     brouard  12277:       printf("\n#****** Result for:");
                   12278:       fprintf(ficrest,"\n#****** Result for:");
                   12279:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12280:       for(j=1;j<=cptcoveff;j++){ 
                   12281:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12282:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12283:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12284:       }
1.235     brouard  12285:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12286:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12287:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12288:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12289:       }        
1.208     brouard  12290:       fprintf(ficrest,"******\n");
1.227     brouard  12291:       fprintf(ficlog,"******\n");
                   12292:       printf("******\n");
1.208     brouard  12293:       
                   12294:       fprintf(ficresstdeij,"\n#****** ");
                   12295:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12296:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12297:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12298:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12299:       }
1.235     brouard  12300:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12301:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12302:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12303:       }        
1.208     brouard  12304:       fprintf(ficresstdeij,"******\n");
                   12305:       fprintf(ficrescveij,"******\n");
                   12306:       
                   12307:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12308:       /* pstamp(ficresvij); */
1.225     brouard  12309:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12310:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12311:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12312:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12313:       }        
1.208     brouard  12314:       fprintf(ficresvij,"******\n");
                   12315:       
                   12316:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12317:       oldm=oldms;savm=savms;
1.235     brouard  12318:       printf(" cvevsij ");
                   12319:       fprintf(ficlog, " cvevsij ");
                   12320:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12321:       printf(" end cvevsij \n ");
                   12322:       fprintf(ficlog, " end cvevsij \n ");
                   12323:       
                   12324:       /*
                   12325:        */
                   12326:       /* goto endfree; */
                   12327:       
                   12328:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12329:       pstamp(ficrest);
                   12330:       
1.269   ! brouard  12331:       epj=vector(1,nlstate+1);
1.208     brouard  12332:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12333:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12334:        cptcod= 0; /* To be deleted */
                   12335:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12336:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12337:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12338:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12339:        if(vpopbased==1)
                   12340:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12341:        else
                   12342:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12343:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12344:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12345:        fprintf(ficrest,"\n");
                   12346:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12347:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12348:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12349:        for(age=bage; age <=fage ;age++){
1.235     brouard  12350:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12351:          if (vpopbased==1) {
                   12352:            if(mobilav ==0){
                   12353:              for(i=1; i<=nlstate;i++)
                   12354:                prlim[i][i]=probs[(int)age][i][k];
                   12355:            }else{ /* mobilav */ 
                   12356:              for(i=1; i<=nlstate;i++)
                   12357:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12358:            }
                   12359:          }
1.219     brouard  12360:          
1.227     brouard  12361:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12362:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12363:          /* printf(" age %4.0f ",age); */
                   12364:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12365:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12366:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12367:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12368:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12369:            }
                   12370:            epj[nlstate+1] +=epj[j];
                   12371:          }
                   12372:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12373:          
1.227     brouard  12374:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12375:            for(j=1;j <=nlstate;j++)
                   12376:              vepp += vareij[i][j][(int)age];
                   12377:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12378:          for(j=1;j <=nlstate;j++){
                   12379:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12380:          }
                   12381:          fprintf(ficrest,"\n");
                   12382:        }
1.208     brouard  12383:       } /* End vpopbased */
1.269   ! brouard  12384:       free_vector(epj,1,nlstate+1);
1.208     brouard  12385:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12386:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12387:       printf("done selection\n");fflush(stdout);
                   12388:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12389:       
1.235     brouard  12390:     } /* End k selection */
1.227     brouard  12391: 
                   12392:     printf("done State-specific expectancies\n");fflush(stdout);
                   12393:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12394: 
1.269   ! brouard  12395:     /* variance-covariance of period prevalence*/
        !          12396:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12397: 
1.227     brouard  12398:     
                   12399:     free_vector(weight,1,n);
                   12400:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12401:     free_imatrix(s,1,maxwav+1,1,n);
                   12402:     free_matrix(anint,1,maxwav,1,n); 
                   12403:     free_matrix(mint,1,maxwav,1,n);
                   12404:     free_ivector(cod,1,n);
                   12405:     free_ivector(tab,1,NCOVMAX);
                   12406:     fclose(ficresstdeij);
                   12407:     fclose(ficrescveij);
                   12408:     fclose(ficresvij);
                   12409:     fclose(ficrest);
                   12410:     fclose(ficpar);
                   12411:     
                   12412:     
1.126     brouard  12413:     /*---------- End : free ----------------*/
1.219     brouard  12414:     if (mobilav!=0 ||mobilavproj !=0)
1.269   ! brouard  12415:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
        !          12416:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12417:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12418:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12419:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12420:   /* endfree:*/
                   12421:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12422:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12423:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12424:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12425:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12426:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12427:   free_matrix(covar,0,NCOVMAX,1,n);
                   12428:   free_matrix(matcov,1,npar,1,npar);
                   12429:   free_matrix(hess,1,npar,1,npar);
                   12430:   /*free_vector(delti,1,npar);*/
                   12431:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12432:   free_matrix(agev,1,maxwav,1,imx);
1.269   ! brouard  12433:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12434:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12435:   
                   12436:   free_ivector(ncodemax,1,NCOVMAX);
                   12437:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12438:   free_ivector(Dummy,-1,NCOVMAX);
                   12439:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12440:   free_ivector(DummyV,1,NCOVMAX);
                   12441:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12442:   free_ivector(Typevar,-1,NCOVMAX);
                   12443:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12444:   free_ivector(TvarsQ,1,NCOVMAX);
                   12445:   free_ivector(TvarsQind,1,NCOVMAX);
                   12446:   free_ivector(TvarsD,1,NCOVMAX);
                   12447:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12448:   free_ivector(TvarFD,1,NCOVMAX);
                   12449:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12450:   free_ivector(TvarF,1,NCOVMAX);
                   12451:   free_ivector(TvarFind,1,NCOVMAX);
                   12452:   free_ivector(TvarV,1,NCOVMAX);
                   12453:   free_ivector(TvarVind,1,NCOVMAX);
                   12454:   free_ivector(TvarA,1,NCOVMAX);
                   12455:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12456:   free_ivector(TvarFQ,1,NCOVMAX);
                   12457:   free_ivector(TvarFQind,1,NCOVMAX);
                   12458:   free_ivector(TvarVD,1,NCOVMAX);
                   12459:   free_ivector(TvarVDind,1,NCOVMAX);
                   12460:   free_ivector(TvarVQ,1,NCOVMAX);
                   12461:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12462:   free_ivector(Tvarsel,1,NCOVMAX);
                   12463:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12464:   free_ivector(Tposprod,1,NCOVMAX);
                   12465:   free_ivector(Tprod,1,NCOVMAX);
                   12466:   free_ivector(Tvaraff,1,NCOVMAX);
                   12467:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12468:   free_ivector(Tage,1,NCOVMAX);
                   12469:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12470:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12471:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12472:   
                   12473:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12474:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12475:   fflush(fichtm);
                   12476:   fflush(ficgp);
                   12477:   
1.227     brouard  12478:   
1.126     brouard  12479:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12480:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12481:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12482:   }else{
                   12483:     printf("End of Imach\n");
                   12484:     fprintf(ficlog,"End of Imach\n");
                   12485:   }
                   12486:   printf("See log file on %s\n",filelog);
                   12487:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12488:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12489:   rend_time = time(NULL);  
                   12490:   end_time = *localtime(&rend_time);
                   12491:   /* tml = *localtime(&end_time.tm_sec); */
                   12492:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12493:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12494:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12495:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12496:   
1.157     brouard  12497:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12498:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12499:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12500:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12501: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12502:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12503:   fclose(fichtm);
                   12504:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12505:   fclose(fichtmcov);
                   12506:   fclose(ficgp);
                   12507:   fclose(ficlog);
                   12508:   /*------ End -----------*/
1.227     brouard  12509:   
                   12510:   
                   12511:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12512: #ifdef WIN32
1.227     brouard  12513:   if (_chdir(pathcd) != 0)
                   12514:     printf("Can't move to directory %s!\n",path);
                   12515:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12516: #else
1.227     brouard  12517:     if(chdir(pathcd) != 0)
                   12518:       printf("Can't move to directory %s!\n", path);
                   12519:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12520: #endif 
1.126     brouard  12521:     printf("Current directory %s!\n",pathcd);
                   12522:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12523:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12524: #ifdef _WIN32
1.126     brouard  12525:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12526: #endif
                   12527:   if(!stat(plotcmd,&info)){
1.158     brouard  12528:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12529:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12530:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12531:     }else
                   12532:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12533: #ifdef __unix
1.126     brouard  12534:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12535:     if(!stat(plotcmd,&info)){
1.158     brouard  12536:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12537:     }else
                   12538:       strcpy(pplotcmd,plotcmd);
                   12539: #endif
                   12540:   }else
                   12541:     strcpy(pplotcmd,plotcmd);
                   12542:   
                   12543:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12544:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12545:   
1.126     brouard  12546:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12547:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12548:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12549:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12550:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12551:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12552:   }
1.158     brouard  12553:   printf(" Successful, please wait...");
1.126     brouard  12554:   while (z[0] != 'q') {
                   12555:     /* chdir(path); */
1.154     brouard  12556:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12557:     scanf("%s",z);
                   12558: /*     if (z[0] == 'c') system("./imach"); */
                   12559:     if (z[0] == 'e') {
1.158     brouard  12560: #ifdef __APPLE__
1.152     brouard  12561:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12562: #elif __linux
                   12563:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12564: #else
1.152     brouard  12565:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12566: #endif
                   12567:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12568:       system(pplotcmd);
1.126     brouard  12569:     }
                   12570:     else if (z[0] == 'g') system(plotcmd);
                   12571:     else if (z[0] == 'q') exit(0);
                   12572:   }
1.227     brouard  12573: end:
1.126     brouard  12574:   while (z[0] != 'q') {
1.195     brouard  12575:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12576:     scanf("%s",z);
                   12577:   }
                   12578: }

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