Annotation of imach/src/imach.c, revision 1.273

1.273   ! brouard     1: /* $Id: imach.c,v 1.272 2017/06/27 10:22:40 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.273   ! brouard     4:   Revision 1.272  2017/06/27 10:22:40  brouard
        !             5:   Summary: Color of backprojection changed from 6 to 5(yellow)
        !             6: 
1.272     brouard     7:   Revision 1.271  2017/06/27 10:17:50  brouard
                      8:   Summary: Some bug with rint
                      9: 
1.271     brouard    10:   Revision 1.270  2017/05/24 05:45:29  brouard
                     11:   *** empty log message ***
                     12: 
1.270     brouard    13:   Revision 1.269  2017/05/23 08:39:25  brouard
                     14:   Summary: Code into subroutine, cleanings
                     15: 
1.269     brouard    16:   Revision 1.268  2017/05/18 20:09:32  brouard
                     17:   Summary: backprojection and confidence intervals of backprevalence
                     18: 
1.268     brouard    19:   Revision 1.267  2017/05/13 10:25:05  brouard
                     20:   Summary: temporary save for backprojection
                     21: 
1.267     brouard    22:   Revision 1.266  2017/05/13 07:26:12  brouard
                     23:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     24: 
1.266     brouard    25:   Revision 1.265  2017/04/26 16:22:11  brouard
                     26:   Summary: imach 0.99r13 Some bugs fixed
                     27: 
1.265     brouard    28:   Revision 1.264  2017/04/26 06:01:29  brouard
                     29:   Summary: Labels in graphs
                     30: 
1.264     brouard    31:   Revision 1.263  2017/04/24 15:23:15  brouard
                     32:   Summary: to save
                     33: 
1.263     brouard    34:   Revision 1.262  2017/04/18 16:48:12  brouard
                     35:   *** empty log message ***
                     36: 
1.262     brouard    37:   Revision 1.261  2017/04/05 10:14:09  brouard
                     38:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     39: 
1.261     brouard    40:   Revision 1.260  2017/04/04 17:46:59  brouard
                     41:   Summary: Gnuplot indexations fixed (humm)
                     42: 
1.260     brouard    43:   Revision 1.259  2017/04/04 13:01:16  brouard
                     44:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     45: 
1.259     brouard    46:   Revision 1.258  2017/04/03 10:17:47  brouard
                     47:   Summary: Version 0.99r12
                     48: 
                     49:   Some cleanings, conformed with updated documentation.
                     50: 
1.258     brouard    51:   Revision 1.257  2017/03/29 16:53:30  brouard
                     52:   Summary: Temp
                     53: 
1.257     brouard    54:   Revision 1.256  2017/03/27 05:50:23  brouard
                     55:   Summary: Temporary
                     56: 
1.256     brouard    57:   Revision 1.255  2017/03/08 16:02:28  brouard
                     58:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                     59: 
1.255     brouard    60:   Revision 1.254  2017/03/08 07:13:00  brouard
                     61:   Summary: Fixing data parameter line
                     62: 
1.254     brouard    63:   Revision 1.253  2016/12/15 11:59:41  brouard
                     64:   Summary: 0.99 in progress
                     65: 
1.253     brouard    66:   Revision 1.252  2016/09/15 21:15:37  brouard
                     67:   *** empty log message ***
                     68: 
1.252     brouard    69:   Revision 1.251  2016/09/15 15:01:13  brouard
                     70:   Summary: not working
                     71: 
1.251     brouard    72:   Revision 1.250  2016/09/08 16:07:27  brouard
                     73:   Summary: continue
                     74: 
1.250     brouard    75:   Revision 1.249  2016/09/07 17:14:18  brouard
                     76:   Summary: Starting values from frequencies
                     77: 
1.249     brouard    78:   Revision 1.248  2016/09/07 14:10:18  brouard
                     79:   *** empty log message ***
                     80: 
1.248     brouard    81:   Revision 1.247  2016/09/02 11:11:21  brouard
                     82:   *** empty log message ***
                     83: 
1.247     brouard    84:   Revision 1.246  2016/09/02 08:49:22  brouard
                     85:   *** empty log message ***
                     86: 
1.246     brouard    87:   Revision 1.245  2016/09/02 07:25:01  brouard
                     88:   *** empty log message ***
                     89: 
1.245     brouard    90:   Revision 1.244  2016/09/02 07:17:34  brouard
                     91:   *** empty log message ***
                     92: 
1.244     brouard    93:   Revision 1.243  2016/09/02 06:45:35  brouard
                     94:   *** empty log message ***
                     95: 
1.243     brouard    96:   Revision 1.242  2016/08/30 15:01:20  brouard
                     97:   Summary: Fixing a lots
                     98: 
1.242     brouard    99:   Revision 1.241  2016/08/29 17:17:25  brouard
                    100:   Summary: gnuplot problem in Back projection to fix
                    101: 
1.241     brouard   102:   Revision 1.240  2016/08/29 07:53:18  brouard
                    103:   Summary: Better
                    104: 
1.240     brouard   105:   Revision 1.239  2016/08/26 15:51:03  brouard
                    106:   Summary: Improvement in Powell output in order to copy and paste
                    107: 
                    108:   Author:
                    109: 
1.239     brouard   110:   Revision 1.238  2016/08/26 14:23:35  brouard
                    111:   Summary: Starting tests of 0.99
                    112: 
1.238     brouard   113:   Revision 1.237  2016/08/26 09:20:19  brouard
                    114:   Summary: to valgrind
                    115: 
1.237     brouard   116:   Revision 1.236  2016/08/25 10:50:18  brouard
                    117:   *** empty log message ***
                    118: 
1.236     brouard   119:   Revision 1.235  2016/08/25 06:59:23  brouard
                    120:   *** empty log message ***
                    121: 
1.235     brouard   122:   Revision 1.234  2016/08/23 16:51:20  brouard
                    123:   *** empty log message ***
                    124: 
1.234     brouard   125:   Revision 1.233  2016/08/23 07:40:50  brouard
                    126:   Summary: not working
                    127: 
1.233     brouard   128:   Revision 1.232  2016/08/22 14:20:21  brouard
                    129:   Summary: not working
                    130: 
1.232     brouard   131:   Revision 1.231  2016/08/22 07:17:15  brouard
                    132:   Summary: not working
                    133: 
1.231     brouard   134:   Revision 1.230  2016/08/22 06:55:53  brouard
                    135:   Summary: Not working
                    136: 
1.230     brouard   137:   Revision 1.229  2016/07/23 09:45:53  brouard
                    138:   Summary: Completing for func too
                    139: 
1.229     brouard   140:   Revision 1.228  2016/07/22 17:45:30  brouard
                    141:   Summary: Fixing some arrays, still debugging
                    142: 
1.227     brouard   143:   Revision 1.226  2016/07/12 18:42:34  brouard
                    144:   Summary: temp
                    145: 
1.226     brouard   146:   Revision 1.225  2016/07/12 08:40:03  brouard
                    147:   Summary: saving but not running
                    148: 
1.225     brouard   149:   Revision 1.224  2016/07/01 13:16:01  brouard
                    150:   Summary: Fixes
                    151: 
1.224     brouard   152:   Revision 1.223  2016/02/19 09:23:35  brouard
                    153:   Summary: temporary
                    154: 
1.223     brouard   155:   Revision 1.222  2016/02/17 08:14:50  brouard
                    156:   Summary: Probably last 0.98 stable version 0.98r6
                    157: 
1.222     brouard   158:   Revision 1.221  2016/02/15 23:35:36  brouard
                    159:   Summary: minor bug
                    160: 
1.220     brouard   161:   Revision 1.219  2016/02/15 00:48:12  brouard
                    162:   *** empty log message ***
                    163: 
1.219     brouard   164:   Revision 1.218  2016/02/12 11:29:23  brouard
                    165:   Summary: 0.99 Back projections
                    166: 
1.218     brouard   167:   Revision 1.217  2015/12/23 17:18:31  brouard
                    168:   Summary: Experimental backcast
                    169: 
1.217     brouard   170:   Revision 1.216  2015/12/18 17:32:11  brouard
                    171:   Summary: 0.98r4 Warning and status=-2
                    172: 
                    173:   Version 0.98r4 is now:
                    174:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    175:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    176:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    177: 
1.216     brouard   178:   Revision 1.215  2015/12/16 08:52:24  brouard
                    179:   Summary: 0.98r4 working
                    180: 
1.215     brouard   181:   Revision 1.214  2015/12/16 06:57:54  brouard
                    182:   Summary: temporary not working
                    183: 
1.214     brouard   184:   Revision 1.213  2015/12/11 18:22:17  brouard
                    185:   Summary: 0.98r4
                    186: 
1.213     brouard   187:   Revision 1.212  2015/11/21 12:47:24  brouard
                    188:   Summary: minor typo
                    189: 
1.212     brouard   190:   Revision 1.211  2015/11/21 12:41:11  brouard
                    191:   Summary: 0.98r3 with some graph of projected cross-sectional
                    192: 
                    193:   Author: Nicolas Brouard
                    194: 
1.211     brouard   195:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   196:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   197:   Summary: Adding ftolpl parameter
                    198:   Author: N Brouard
                    199: 
                    200:   We had difficulties to get smoothed confidence intervals. It was due
                    201:   to the period prevalence which wasn't computed accurately. The inner
                    202:   parameter ftolpl is now an outer parameter of the .imach parameter
                    203:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    204:   computation are long.
                    205: 
1.209     brouard   206:   Revision 1.208  2015/11/17 14:31:57  brouard
                    207:   Summary: temporary
                    208: 
1.208     brouard   209:   Revision 1.207  2015/10/27 17:36:57  brouard
                    210:   *** empty log message ***
                    211: 
1.207     brouard   212:   Revision 1.206  2015/10/24 07:14:11  brouard
                    213:   *** empty log message ***
                    214: 
1.206     brouard   215:   Revision 1.205  2015/10/23 15:50:53  brouard
                    216:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    217: 
1.205     brouard   218:   Revision 1.204  2015/10/01 16:20:26  brouard
                    219:   Summary: Some new graphs of contribution to likelihood
                    220: 
1.204     brouard   221:   Revision 1.203  2015/09/30 17:45:14  brouard
                    222:   Summary: looking at better estimation of the hessian
                    223: 
                    224:   Also a better criteria for convergence to the period prevalence And
                    225:   therefore adding the number of years needed to converge. (The
                    226:   prevalence in any alive state shold sum to one
                    227: 
1.203     brouard   228:   Revision 1.202  2015/09/22 19:45:16  brouard
                    229:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    230: 
1.202     brouard   231:   Revision 1.201  2015/09/15 17:34:58  brouard
                    232:   Summary: 0.98r0
                    233: 
                    234:   - Some new graphs like suvival functions
                    235:   - Some bugs fixed like model=1+age+V2.
                    236: 
1.201     brouard   237:   Revision 1.200  2015/09/09 16:53:55  brouard
                    238:   Summary: Big bug thanks to Flavia
                    239: 
                    240:   Even model=1+age+V2. did not work anymore
                    241: 
1.200     brouard   242:   Revision 1.199  2015/09/07 14:09:23  brouard
                    243:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    244: 
1.199     brouard   245:   Revision 1.198  2015/09/03 07:14:39  brouard
                    246:   Summary: 0.98q5 Flavia
                    247: 
1.198     brouard   248:   Revision 1.197  2015/09/01 18:24:39  brouard
                    249:   *** empty log message ***
                    250: 
1.197     brouard   251:   Revision 1.196  2015/08/18 23:17:52  brouard
                    252:   Summary: 0.98q5
                    253: 
1.196     brouard   254:   Revision 1.195  2015/08/18 16:28:39  brouard
                    255:   Summary: Adding a hack for testing purpose
                    256: 
                    257:   After reading the title, ftol and model lines, if the comment line has
                    258:   a q, starting with #q, the answer at the end of the run is quit. It
                    259:   permits to run test files in batch with ctest. The former workaround was
                    260:   $ echo q | imach foo.imach
                    261: 
1.195     brouard   262:   Revision 1.194  2015/08/18 13:32:00  brouard
                    263:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    264: 
1.194     brouard   265:   Revision 1.193  2015/08/04 07:17:42  brouard
                    266:   Summary: 0.98q4
                    267: 
1.193     brouard   268:   Revision 1.192  2015/07/16 16:49:02  brouard
                    269:   Summary: Fixing some outputs
                    270: 
1.192     brouard   271:   Revision 1.191  2015/07/14 10:00:33  brouard
                    272:   Summary: Some fixes
                    273: 
1.191     brouard   274:   Revision 1.190  2015/05/05 08:51:13  brouard
                    275:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    276: 
                    277:   Fix 1+age+.
                    278: 
1.190     brouard   279:   Revision 1.189  2015/04/30 14:45:16  brouard
                    280:   Summary: 0.98q2
                    281: 
1.189     brouard   282:   Revision 1.188  2015/04/30 08:27:53  brouard
                    283:   *** empty log message ***
                    284: 
1.188     brouard   285:   Revision 1.187  2015/04/29 09:11:15  brouard
                    286:   *** empty log message ***
                    287: 
1.187     brouard   288:   Revision 1.186  2015/04/23 12:01:52  brouard
                    289:   Summary: V1*age is working now, version 0.98q1
                    290: 
                    291:   Some codes had been disabled in order to simplify and Vn*age was
                    292:   working in the optimization phase, ie, giving correct MLE parameters,
                    293:   but, as usual, outputs were not correct and program core dumped.
                    294: 
1.186     brouard   295:   Revision 1.185  2015/03/11 13:26:42  brouard
                    296:   Summary: Inclusion of compile and links command line for Intel Compiler
                    297: 
1.185     brouard   298:   Revision 1.184  2015/03/11 11:52:39  brouard
                    299:   Summary: Back from Windows 8. Intel Compiler
                    300: 
1.184     brouard   301:   Revision 1.183  2015/03/10 20:34:32  brouard
                    302:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    303: 
                    304:   We use directest instead of original Powell test; probably no
                    305:   incidence on the results, but better justifications;
                    306:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    307:   wrong results.
                    308: 
1.183     brouard   309:   Revision 1.182  2015/02/12 08:19:57  brouard
                    310:   Summary: Trying to keep directest which seems simpler and more general
                    311:   Author: Nicolas Brouard
                    312: 
1.182     brouard   313:   Revision 1.181  2015/02/11 23:22:24  brouard
                    314:   Summary: Comments on Powell added
                    315: 
                    316:   Author:
                    317: 
1.181     brouard   318:   Revision 1.180  2015/02/11 17:33:45  brouard
                    319:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    320: 
1.180     brouard   321:   Revision 1.179  2015/01/04 09:57:06  brouard
                    322:   Summary: back to OS/X
                    323: 
1.179     brouard   324:   Revision 1.178  2015/01/04 09:35:48  brouard
                    325:   *** empty log message ***
                    326: 
1.178     brouard   327:   Revision 1.177  2015/01/03 18:40:56  brouard
                    328:   Summary: Still testing ilc32 on OSX
                    329: 
1.177     brouard   330:   Revision 1.176  2015/01/03 16:45:04  brouard
                    331:   *** empty log message ***
                    332: 
1.176     brouard   333:   Revision 1.175  2015/01/03 16:33:42  brouard
                    334:   *** empty log message ***
                    335: 
1.175     brouard   336:   Revision 1.174  2015/01/03 16:15:49  brouard
                    337:   Summary: Still in cross-compilation
                    338: 
1.174     brouard   339:   Revision 1.173  2015/01/03 12:06:26  brouard
                    340:   Summary: trying to detect cross-compilation
                    341: 
1.173     brouard   342:   Revision 1.172  2014/12/27 12:07:47  brouard
                    343:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    344: 
1.172     brouard   345:   Revision 1.171  2014/12/23 13:26:59  brouard
                    346:   Summary: Back from Visual C
                    347: 
                    348:   Still problem with utsname.h on Windows
                    349: 
1.171     brouard   350:   Revision 1.170  2014/12/23 11:17:12  brouard
                    351:   Summary: Cleaning some \%% back to %%
                    352: 
                    353:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    354: 
1.170     brouard   355:   Revision 1.169  2014/12/22 23:08:31  brouard
                    356:   Summary: 0.98p
                    357: 
                    358:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    359: 
1.169     brouard   360:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   361:   Summary: update
1.169     brouard   362: 
1.168     brouard   363:   Revision 1.167  2014/12/22 13:50:56  brouard
                    364:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    365: 
                    366:   Testing on Linux 64
                    367: 
1.167     brouard   368:   Revision 1.166  2014/12/22 11:40:47  brouard
                    369:   *** empty log message ***
                    370: 
1.166     brouard   371:   Revision 1.165  2014/12/16 11:20:36  brouard
                    372:   Summary: After compiling on Visual C
                    373: 
                    374:   * imach.c (Module): Merging 1.61 to 1.162
                    375: 
1.165     brouard   376:   Revision 1.164  2014/12/16 10:52:11  brouard
                    377:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    378: 
                    379:   * imach.c (Module): Merging 1.61 to 1.162
                    380: 
1.164     brouard   381:   Revision 1.163  2014/12/16 10:30:11  brouard
                    382:   * imach.c (Module): Merging 1.61 to 1.162
                    383: 
1.163     brouard   384:   Revision 1.162  2014/09/25 11:43:39  brouard
                    385:   Summary: temporary backup 0.99!
                    386: 
1.162     brouard   387:   Revision 1.1  2014/09/16 11:06:58  brouard
                    388:   Summary: With some code (wrong) for nlopt
                    389: 
                    390:   Author:
                    391: 
                    392:   Revision 1.161  2014/09/15 20:41:41  brouard
                    393:   Summary: Problem with macro SQR on Intel compiler
                    394: 
1.161     brouard   395:   Revision 1.160  2014/09/02 09:24:05  brouard
                    396:   *** empty log message ***
                    397: 
1.160     brouard   398:   Revision 1.159  2014/09/01 10:34:10  brouard
                    399:   Summary: WIN32
                    400:   Author: Brouard
                    401: 
1.159     brouard   402:   Revision 1.158  2014/08/27 17:11:51  brouard
                    403:   *** empty log message ***
                    404: 
1.158     brouard   405:   Revision 1.157  2014/08/27 16:26:55  brouard
                    406:   Summary: Preparing windows Visual studio version
                    407:   Author: Brouard
                    408: 
                    409:   In order to compile on Visual studio, time.h is now correct and time_t
                    410:   and tm struct should be used. difftime should be used but sometimes I
                    411:   just make the differences in raw time format (time(&now).
                    412:   Trying to suppress #ifdef LINUX
                    413:   Add xdg-open for __linux in order to open default browser.
                    414: 
1.157     brouard   415:   Revision 1.156  2014/08/25 20:10:10  brouard
                    416:   *** empty log message ***
                    417: 
1.156     brouard   418:   Revision 1.155  2014/08/25 18:32:34  brouard
                    419:   Summary: New compile, minor changes
                    420:   Author: Brouard
                    421: 
1.155     brouard   422:   Revision 1.154  2014/06/20 17:32:08  brouard
                    423:   Summary: Outputs now all graphs of convergence to period prevalence
                    424: 
1.154     brouard   425:   Revision 1.153  2014/06/20 16:45:46  brouard
                    426:   Summary: If 3 live state, convergence to period prevalence on same graph
                    427:   Author: Brouard
                    428: 
1.153     brouard   429:   Revision 1.152  2014/06/18 17:54:09  brouard
                    430:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    431: 
1.152     brouard   432:   Revision 1.151  2014/06/18 16:43:30  brouard
                    433:   *** empty log message ***
                    434: 
1.151     brouard   435:   Revision 1.150  2014/06/18 16:42:35  brouard
                    436:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    437:   Author: brouard
                    438: 
1.150     brouard   439:   Revision 1.149  2014/06/18 15:51:14  brouard
                    440:   Summary: Some fixes in parameter files errors
                    441:   Author: Nicolas Brouard
                    442: 
1.149     brouard   443:   Revision 1.148  2014/06/17 17:38:48  brouard
                    444:   Summary: Nothing new
                    445:   Author: Brouard
                    446: 
                    447:   Just a new packaging for OS/X version 0.98nS
                    448: 
1.148     brouard   449:   Revision 1.147  2014/06/16 10:33:11  brouard
                    450:   *** empty log message ***
                    451: 
1.147     brouard   452:   Revision 1.146  2014/06/16 10:20:28  brouard
                    453:   Summary: Merge
                    454:   Author: Brouard
                    455: 
                    456:   Merge, before building revised version.
                    457: 
1.146     brouard   458:   Revision 1.145  2014/06/10 21:23:15  brouard
                    459:   Summary: Debugging with valgrind
                    460:   Author: Nicolas Brouard
                    461: 
                    462:   Lot of changes in order to output the results with some covariates
                    463:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    464:   improve the code.
                    465:   No more memory valgrind error but a lot has to be done in order to
                    466:   continue the work of splitting the code into subroutines.
                    467:   Also, decodemodel has been improved. Tricode is still not
                    468:   optimal. nbcode should be improved. Documentation has been added in
                    469:   the source code.
                    470: 
1.144     brouard   471:   Revision 1.143  2014/01/26 09:45:38  brouard
                    472:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    473: 
                    474:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    475:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    476: 
1.143     brouard   477:   Revision 1.142  2014/01/26 03:57:36  brouard
                    478:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    479: 
                    480:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    481: 
1.142     brouard   482:   Revision 1.141  2014/01/26 02:42:01  brouard
                    483:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    484: 
1.141     brouard   485:   Revision 1.140  2011/09/02 10:37:54  brouard
                    486:   Summary: times.h is ok with mingw32 now.
                    487: 
1.140     brouard   488:   Revision 1.139  2010/06/14 07:50:17  brouard
                    489:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    490:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    491: 
1.139     brouard   492:   Revision 1.138  2010/04/30 18:19:40  brouard
                    493:   *** empty log message ***
                    494: 
1.138     brouard   495:   Revision 1.137  2010/04/29 18:11:38  brouard
                    496:   (Module): Checking covariates for more complex models
                    497:   than V1+V2. A lot of change to be done. Unstable.
                    498: 
1.137     brouard   499:   Revision 1.136  2010/04/26 20:30:53  brouard
                    500:   (Module): merging some libgsl code. Fixing computation
                    501:   of likelione (using inter/intrapolation if mle = 0) in order to
                    502:   get same likelihood as if mle=1.
                    503:   Some cleaning of code and comments added.
                    504: 
1.136     brouard   505:   Revision 1.135  2009/10/29 15:33:14  brouard
                    506:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    507: 
1.135     brouard   508:   Revision 1.134  2009/10/29 13:18:53  brouard
                    509:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    510: 
1.134     brouard   511:   Revision 1.133  2009/07/06 10:21:25  brouard
                    512:   just nforces
                    513: 
1.133     brouard   514:   Revision 1.132  2009/07/06 08:22:05  brouard
                    515:   Many tings
                    516: 
1.132     brouard   517:   Revision 1.131  2009/06/20 16:22:47  brouard
                    518:   Some dimensions resccaled
                    519: 
1.131     brouard   520:   Revision 1.130  2009/05/26 06:44:34  brouard
                    521:   (Module): Max Covariate is now set to 20 instead of 8. A
                    522:   lot of cleaning with variables initialized to 0. Trying to make
                    523:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    524: 
1.130     brouard   525:   Revision 1.129  2007/08/31 13:49:27  lievre
                    526:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    527: 
1.129     lievre    528:   Revision 1.128  2006/06/30 13:02:05  brouard
                    529:   (Module): Clarifications on computing e.j
                    530: 
1.128     brouard   531:   Revision 1.127  2006/04/28 18:11:50  brouard
                    532:   (Module): Yes the sum of survivors was wrong since
                    533:   imach-114 because nhstepm was no more computed in the age
                    534:   loop. Now we define nhstepma in the age loop.
                    535:   (Module): In order to speed up (in case of numerous covariates) we
                    536:   compute health expectancies (without variances) in a first step
                    537:   and then all the health expectancies with variances or standard
                    538:   deviation (needs data from the Hessian matrices) which slows the
                    539:   computation.
                    540:   In the future we should be able to stop the program is only health
                    541:   expectancies and graph are needed without standard deviations.
                    542: 
1.127     brouard   543:   Revision 1.126  2006/04/28 17:23:28  brouard
                    544:   (Module): Yes the sum of survivors was wrong since
                    545:   imach-114 because nhstepm was no more computed in the age
                    546:   loop. Now we define nhstepma in the age loop.
                    547:   Version 0.98h
                    548: 
1.126     brouard   549:   Revision 1.125  2006/04/04 15:20:31  lievre
                    550:   Errors in calculation of health expectancies. Age was not initialized.
                    551:   Forecasting file added.
                    552: 
                    553:   Revision 1.124  2006/03/22 17:13:53  lievre
                    554:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    555:   The log-likelihood is printed in the log file
                    556: 
                    557:   Revision 1.123  2006/03/20 10:52:43  brouard
                    558:   * imach.c (Module): <title> changed, corresponds to .htm file
                    559:   name. <head> headers where missing.
                    560: 
                    561:   * imach.c (Module): Weights can have a decimal point as for
                    562:   English (a comma might work with a correct LC_NUMERIC environment,
                    563:   otherwise the weight is truncated).
                    564:   Modification of warning when the covariates values are not 0 or
                    565:   1.
                    566:   Version 0.98g
                    567: 
                    568:   Revision 1.122  2006/03/20 09:45:41  brouard
                    569:   (Module): Weights can have a decimal point as for
                    570:   English (a comma might work with a correct LC_NUMERIC environment,
                    571:   otherwise the weight is truncated).
                    572:   Modification of warning when the covariates values are not 0 or
                    573:   1.
                    574:   Version 0.98g
                    575: 
                    576:   Revision 1.121  2006/03/16 17:45:01  lievre
                    577:   * imach.c (Module): Comments concerning covariates added
                    578: 
                    579:   * imach.c (Module): refinements in the computation of lli if
                    580:   status=-2 in order to have more reliable computation if stepm is
                    581:   not 1 month. Version 0.98f
                    582: 
                    583:   Revision 1.120  2006/03/16 15:10:38  lievre
                    584:   (Module): refinements in the computation of lli if
                    585:   status=-2 in order to have more reliable computation if stepm is
                    586:   not 1 month. Version 0.98f
                    587: 
                    588:   Revision 1.119  2006/03/15 17:42:26  brouard
                    589:   (Module): Bug if status = -2, the loglikelihood was
                    590:   computed as likelihood omitting the logarithm. Version O.98e
                    591: 
                    592:   Revision 1.118  2006/03/14 18:20:07  brouard
                    593:   (Module): varevsij Comments added explaining the second
                    594:   table of variances if popbased=1 .
                    595:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    596:   (Module): Function pstamp added
                    597:   (Module): Version 0.98d
                    598: 
                    599:   Revision 1.117  2006/03/14 17:16:22  brouard
                    600:   (Module): varevsij Comments added explaining the second
                    601:   table of variances if popbased=1 .
                    602:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    603:   (Module): Function pstamp added
                    604:   (Module): Version 0.98d
                    605: 
                    606:   Revision 1.116  2006/03/06 10:29:27  brouard
                    607:   (Module): Variance-covariance wrong links and
                    608:   varian-covariance of ej. is needed (Saito).
                    609: 
                    610:   Revision 1.115  2006/02/27 12:17:45  brouard
                    611:   (Module): One freematrix added in mlikeli! 0.98c
                    612: 
                    613:   Revision 1.114  2006/02/26 12:57:58  brouard
                    614:   (Module): Some improvements in processing parameter
                    615:   filename with strsep.
                    616: 
                    617:   Revision 1.113  2006/02/24 14:20:24  brouard
                    618:   (Module): Memory leaks checks with valgrind and:
                    619:   datafile was not closed, some imatrix were not freed and on matrix
                    620:   allocation too.
                    621: 
                    622:   Revision 1.112  2006/01/30 09:55:26  brouard
                    623:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    624: 
                    625:   Revision 1.111  2006/01/25 20:38:18  brouard
                    626:   (Module): Lots of cleaning and bugs added (Gompertz)
                    627:   (Module): Comments can be added in data file. Missing date values
                    628:   can be a simple dot '.'.
                    629: 
                    630:   Revision 1.110  2006/01/25 00:51:50  brouard
                    631:   (Module): Lots of cleaning and bugs added (Gompertz)
                    632: 
                    633:   Revision 1.109  2006/01/24 19:37:15  brouard
                    634:   (Module): Comments (lines starting with a #) are allowed in data.
                    635: 
                    636:   Revision 1.108  2006/01/19 18:05:42  lievre
                    637:   Gnuplot problem appeared...
                    638:   To be fixed
                    639: 
                    640:   Revision 1.107  2006/01/19 16:20:37  brouard
                    641:   Test existence of gnuplot in imach path
                    642: 
                    643:   Revision 1.106  2006/01/19 13:24:36  brouard
                    644:   Some cleaning and links added in html output
                    645: 
                    646:   Revision 1.105  2006/01/05 20:23:19  lievre
                    647:   *** empty log message ***
                    648: 
                    649:   Revision 1.104  2005/09/30 16:11:43  lievre
                    650:   (Module): sump fixed, loop imx fixed, and simplifications.
                    651:   (Module): If the status is missing at the last wave but we know
                    652:   that the person is alive, then we can code his/her status as -2
                    653:   (instead of missing=-1 in earlier versions) and his/her
                    654:   contributions to the likelihood is 1 - Prob of dying from last
                    655:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    656:   the healthy state at last known wave). Version is 0.98
                    657: 
                    658:   Revision 1.103  2005/09/30 15:54:49  lievre
                    659:   (Module): sump fixed, loop imx fixed, and simplifications.
                    660: 
                    661:   Revision 1.102  2004/09/15 17:31:30  brouard
                    662:   Add the possibility to read data file including tab characters.
                    663: 
                    664:   Revision 1.101  2004/09/15 10:38:38  brouard
                    665:   Fix on curr_time
                    666: 
                    667:   Revision 1.100  2004/07/12 18:29:06  brouard
                    668:   Add version for Mac OS X. Just define UNIX in Makefile
                    669: 
                    670:   Revision 1.99  2004/06/05 08:57:40  brouard
                    671:   *** empty log message ***
                    672: 
                    673:   Revision 1.98  2004/05/16 15:05:56  brouard
                    674:   New version 0.97 . First attempt to estimate force of mortality
                    675:   directly from the data i.e. without the need of knowing the health
                    676:   state at each age, but using a Gompertz model: log u =a + b*age .
                    677:   This is the basic analysis of mortality and should be done before any
                    678:   other analysis, in order to test if the mortality estimated from the
                    679:   cross-longitudinal survey is different from the mortality estimated
                    680:   from other sources like vital statistic data.
                    681: 
                    682:   The same imach parameter file can be used but the option for mle should be -3.
                    683: 
1.133     brouard   684:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   685:   former routines in order to include the new code within the former code.
                    686: 
                    687:   The output is very simple: only an estimate of the intercept and of
                    688:   the slope with 95% confident intervals.
                    689: 
                    690:   Current limitations:
                    691:   A) Even if you enter covariates, i.e. with the
                    692:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    693:   B) There is no computation of Life Expectancy nor Life Table.
                    694: 
                    695:   Revision 1.97  2004/02/20 13:25:42  lievre
                    696:   Version 0.96d. Population forecasting command line is (temporarily)
                    697:   suppressed.
                    698: 
                    699:   Revision 1.96  2003/07/15 15:38:55  brouard
                    700:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    701:   rewritten within the same printf. Workaround: many printfs.
                    702: 
                    703:   Revision 1.95  2003/07/08 07:54:34  brouard
                    704:   * imach.c (Repository):
                    705:   (Repository): Using imachwizard code to output a more meaningful covariance
                    706:   matrix (cov(a12,c31) instead of numbers.
                    707: 
                    708:   Revision 1.94  2003/06/27 13:00:02  brouard
                    709:   Just cleaning
                    710: 
                    711:   Revision 1.93  2003/06/25 16:33:55  brouard
                    712:   (Module): On windows (cygwin) function asctime_r doesn't
                    713:   exist so I changed back to asctime which exists.
                    714:   (Module): Version 0.96b
                    715: 
                    716:   Revision 1.92  2003/06/25 16:30:45  brouard
                    717:   (Module): On windows (cygwin) function asctime_r doesn't
                    718:   exist so I changed back to asctime which exists.
                    719: 
                    720:   Revision 1.91  2003/06/25 15:30:29  brouard
                    721:   * imach.c (Repository): Duplicated warning errors corrected.
                    722:   (Repository): Elapsed time after each iteration is now output. It
                    723:   helps to forecast when convergence will be reached. Elapsed time
                    724:   is stamped in powell.  We created a new html file for the graphs
                    725:   concerning matrix of covariance. It has extension -cov.htm.
                    726: 
                    727:   Revision 1.90  2003/06/24 12:34:15  brouard
                    728:   (Module): Some bugs corrected for windows. Also, when
                    729:   mle=-1 a template is output in file "or"mypar.txt with the design
                    730:   of the covariance matrix to be input.
                    731: 
                    732:   Revision 1.89  2003/06/24 12:30:52  brouard
                    733:   (Module): Some bugs corrected for windows. Also, when
                    734:   mle=-1 a template is output in file "or"mypar.txt with the design
                    735:   of the covariance matrix to be input.
                    736: 
                    737:   Revision 1.88  2003/06/23 17:54:56  brouard
                    738:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    739: 
                    740:   Revision 1.87  2003/06/18 12:26:01  brouard
                    741:   Version 0.96
                    742: 
                    743:   Revision 1.86  2003/06/17 20:04:08  brouard
                    744:   (Module): Change position of html and gnuplot routines and added
                    745:   routine fileappend.
                    746: 
                    747:   Revision 1.85  2003/06/17 13:12:43  brouard
                    748:   * imach.c (Repository): Check when date of death was earlier that
                    749:   current date of interview. It may happen when the death was just
                    750:   prior to the death. In this case, dh was negative and likelihood
                    751:   was wrong (infinity). We still send an "Error" but patch by
                    752:   assuming that the date of death was just one stepm after the
                    753:   interview.
                    754:   (Repository): Because some people have very long ID (first column)
                    755:   we changed int to long in num[] and we added a new lvector for
                    756:   memory allocation. But we also truncated to 8 characters (left
                    757:   truncation)
                    758:   (Repository): No more line truncation errors.
                    759: 
                    760:   Revision 1.84  2003/06/13 21:44:43  brouard
                    761:   * imach.c (Repository): Replace "freqsummary" at a correct
                    762:   place. It differs from routine "prevalence" which may be called
                    763:   many times. Probs is memory consuming and must be used with
                    764:   parcimony.
                    765:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    766: 
                    767:   Revision 1.83  2003/06/10 13:39:11  lievre
                    768:   *** empty log message ***
                    769: 
                    770:   Revision 1.82  2003/06/05 15:57:20  brouard
                    771:   Add log in  imach.c and  fullversion number is now printed.
                    772: 
                    773: */
                    774: /*
                    775:    Interpolated Markov Chain
                    776: 
                    777:   Short summary of the programme:
                    778:   
1.227     brouard   779:   This program computes Healthy Life Expectancies or State-specific
                    780:   (if states aren't health statuses) Expectancies from
                    781:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    782: 
                    783:   -1- a first survey ("cross") where individuals from different ages
                    784:   are interviewed on their health status or degree of disability (in
                    785:   the case of a health survey which is our main interest)
                    786: 
                    787:   -2- at least a second wave of interviews ("longitudinal") which
                    788:   measure each change (if any) in individual health status.  Health
                    789:   expectancies are computed from the time spent in each health state
                    790:   according to a model. More health states you consider, more time is
                    791:   necessary to reach the Maximum Likelihood of the parameters involved
                    792:   in the model.  The simplest model is the multinomial logistic model
                    793:   where pij is the probability to be observed in state j at the second
                    794:   wave conditional to be observed in state i at the first
                    795:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    796:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    797:   have a more complex model than "constant and age", you should modify
                    798:   the program where the markup *Covariates have to be included here
                    799:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   800:   convergence.
                    801: 
                    802:   The advantage of this computer programme, compared to a simple
                    803:   multinomial logistic model, is clear when the delay between waves is not
                    804:   identical for each individual. Also, if a individual missed an
                    805:   intermediate interview, the information is lost, but taken into
                    806:   account using an interpolation or extrapolation.  
                    807: 
                    808:   hPijx is the probability to be observed in state i at age x+h
                    809:   conditional to the observed state i at age x. The delay 'h' can be
                    810:   split into an exact number (nh*stepm) of unobserved intermediate
                    811:   states. This elementary transition (by month, quarter,
                    812:   semester or year) is modelled as a multinomial logistic.  The hPx
                    813:   matrix is simply the matrix product of nh*stepm elementary matrices
                    814:   and the contribution of each individual to the likelihood is simply
                    815:   hPijx.
                    816: 
                    817:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   818:   of the life expectancies. It also computes the period (stable) prevalence.
                    819: 
                    820: Back prevalence and projections:
1.227     brouard   821: 
                    822:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    823:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    824:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    825:    mobilavproj)
                    826: 
                    827:     Computes the back prevalence limit for any combination of
                    828:     covariate values k at any age between ageminpar and agemaxpar and
                    829:     returns it in **bprlim. In the loops,
                    830: 
                    831:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    832:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    833: 
                    834:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   835:    Computes for any combination of covariates k and any age between bage and fage 
                    836:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    837:                        oldm=oldms;savm=savms;
1.227     brouard   838: 
1.267     brouard   839:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   840:      Computes the transition matrix starting at age 'age' over
                    841:      'nhstepm*hstepm*stepm' months (i.e. until
                    842:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   843:      nhstepm*hstepm matrices. 
                    844: 
                    845:      Returns p3mat[i][j][h] after calling
                    846:      p3mat[i][j][h]=matprod2(newm,
                    847:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    848:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    849:      oldm);
1.226     brouard   850: 
                    851: Important routines
                    852: 
                    853: - func (or funcone), computes logit (pij) distinguishing
                    854:   o fixed variables (single or product dummies or quantitative);
                    855:   o varying variables by:
                    856:    (1) wave (single, product dummies, quantitative), 
                    857:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    858:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    859:        % varying dummy (not done) or quantitative (not done);
                    860: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    861:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    862: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    863:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    864:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   865: 
1.226     brouard   866: 
                    867:   
1.133     brouard   868:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    869:            Institut national d'études démographiques, Paris.
1.126     brouard   870:   This software have been partly granted by Euro-REVES, a concerted action
                    871:   from the European Union.
                    872:   It is copyrighted identically to a GNU software product, ie programme and
                    873:   software can be distributed freely for non commercial use. Latest version
                    874:   can be accessed at http://euroreves.ined.fr/imach .
                    875: 
                    876:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    877:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    878:   
                    879:   **********************************************************************/
                    880: /*
                    881:   main
                    882:   read parameterfile
                    883:   read datafile
                    884:   concatwav
                    885:   freqsummary
                    886:   if (mle >= 1)
                    887:     mlikeli
                    888:   print results files
                    889:   if mle==1 
                    890:      computes hessian
                    891:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    892:       begin-prev-date,...
                    893:   open gnuplot file
                    894:   open html file
1.145     brouard   895:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    896:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    897:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    898:     freexexit2 possible for memory heap.
                    899: 
                    900:   h Pij x                         | pij_nom  ficrestpij
                    901:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    902:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    903:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    904: 
                    905:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    906:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    907:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    908:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    909:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    910: 
1.126     brouard   911:   forecasting if prevfcast==1 prevforecast call prevalence()
                    912:   health expectancies
                    913:   Variance-covariance of DFLE
                    914:   prevalence()
                    915:    movingaverage()
                    916:   varevsij() 
                    917:   if popbased==1 varevsij(,popbased)
                    918:   total life expectancies
                    919:   Variance of period (stable) prevalence
                    920:  end
                    921: */
                    922: 
1.187     brouard   923: /* #define DEBUG */
                    924: /* #define DEBUGBRENT */
1.203     brouard   925: /* #define DEBUGLINMIN */
                    926: /* #define DEBUGHESS */
                    927: #define DEBUGHESSIJ
1.224     brouard   928: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   929: #define POWELL /* Instead of NLOPT */
1.224     brouard   930: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   931: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    932: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   933: 
                    934: #include <math.h>
                    935: #include <stdio.h>
                    936: #include <stdlib.h>
                    937: #include <string.h>
1.226     brouard   938: #include <ctype.h>
1.159     brouard   939: 
                    940: #ifdef _WIN32
                    941: #include <io.h>
1.172     brouard   942: #include <windows.h>
                    943: #include <tchar.h>
1.159     brouard   944: #else
1.126     brouard   945: #include <unistd.h>
1.159     brouard   946: #endif
1.126     brouard   947: 
                    948: #include <limits.h>
                    949: #include <sys/types.h>
1.171     brouard   950: 
                    951: #if defined(__GNUC__)
                    952: #include <sys/utsname.h> /* Doesn't work on Windows */
                    953: #endif
                    954: 
1.126     brouard   955: #include <sys/stat.h>
                    956: #include <errno.h>
1.159     brouard   957: /* extern int errno; */
1.126     brouard   958: 
1.157     brouard   959: /* #ifdef LINUX */
                    960: /* #include <time.h> */
                    961: /* #include "timeval.h" */
                    962: /* #else */
                    963: /* #include <sys/time.h> */
                    964: /* #endif */
                    965: 
1.126     brouard   966: #include <time.h>
                    967: 
1.136     brouard   968: #ifdef GSL
                    969: #include <gsl/gsl_errno.h>
                    970: #include <gsl/gsl_multimin.h>
                    971: #endif
                    972: 
1.167     brouard   973: 
1.162     brouard   974: #ifdef NLOPT
                    975: #include <nlopt.h>
                    976: typedef struct {
                    977:   double (* function)(double [] );
                    978: } myfunc_data ;
                    979: #endif
                    980: 
1.126     brouard   981: /* #include <libintl.h> */
                    982: /* #define _(String) gettext (String) */
                    983: 
1.251     brouard   984: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard   985: 
                    986: #define GNUPLOTPROGRAM "gnuplot"
                    987: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                    988: #define FILENAMELENGTH 132
                    989: 
                    990: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                    991: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                    992: 
1.144     brouard   993: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                    994: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard   995: 
                    996: #define NINTERVMAX 8
1.144     brouard   997: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                    998: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                    999: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1000: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1001: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1002: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1003: #define MAXN 20000
1.144     brouard  1004: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1005: /* #define AGESUP 130 */
                   1006: #define AGESUP 150
1.268     brouard  1007: #define AGEINF 0
1.218     brouard  1008: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1009: #define AGEBASE 40
1.194     brouard  1010: #define AGEOVERFLOW 1.e20
1.164     brouard  1011: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1012: #ifdef _WIN32
                   1013: #define DIRSEPARATOR '\\'
                   1014: #define CHARSEPARATOR "\\"
                   1015: #define ODIRSEPARATOR '/'
                   1016: #else
1.126     brouard  1017: #define DIRSEPARATOR '/'
                   1018: #define CHARSEPARATOR "/"
                   1019: #define ODIRSEPARATOR '\\'
                   1020: #endif
                   1021: 
1.273   ! brouard  1022: /* $Id: imach.c,v 1.272 2017/06/27 10:22:40 brouard Exp $ */
1.126     brouard  1023: /* $State: Exp $ */
1.196     brouard  1024: #include "version.h"
                   1025: char version[]=__IMACH_VERSION__;
1.224     brouard  1026: char copyright[]="February 2016,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.273   ! brouard  1027: char fullversion[]="$Revision: 1.272 $ $Date: 2017/06/27 10:22:40 $"; 
1.126     brouard  1028: char strstart[80];
                   1029: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1030: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1031: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1032: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1033: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1034: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1035: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1036: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1037: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1038: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1039: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1040: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1041: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1042: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1043: int nsd=0; /**< Total number of single dummy variables (output) */
                   1044: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1045: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1046: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1047: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1048: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1049: int cptcov=0; /* Working variable */
1.218     brouard  1050: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1051: int npar=NPARMAX;
                   1052: int nlstate=2; /* Number of live states */
                   1053: int ndeath=1; /* Number of dead states */
1.130     brouard  1054: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1055: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1056: int popbased=0;
                   1057: 
                   1058: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1059: int maxwav=0; /* Maxim number of waves */
                   1060: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1061: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1062: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1063:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1064: int mle=1, weightopt=0;
1.126     brouard  1065: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1066: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1067: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1068:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1069: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1070: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1071: 
1.130     brouard  1072: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1073: double **matprod2(); /* test */
1.126     brouard  1074: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1075: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1076: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1077: 
1.136     brouard  1078: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1079: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1080: FILE *ficlog, *ficrespow;
1.130     brouard  1081: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1082: double fretone; /* Only one call to likelihood */
1.130     brouard  1083: long ipmx=0; /* Number of contributions */
1.126     brouard  1084: double sw; /* Sum of weights */
                   1085: char filerespow[FILENAMELENGTH];
                   1086: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1087: FILE *ficresilk;
                   1088: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1089: FILE *ficresprobmorprev;
                   1090: FILE *fichtm, *fichtmcov; /* Html File */
                   1091: FILE *ficreseij;
                   1092: char filerese[FILENAMELENGTH];
                   1093: FILE *ficresstdeij;
                   1094: char fileresstde[FILENAMELENGTH];
                   1095: FILE *ficrescveij;
                   1096: char filerescve[FILENAMELENGTH];
                   1097: FILE  *ficresvij;
                   1098: char fileresv[FILENAMELENGTH];
1.269     brouard  1099: 
1.126     brouard  1100: char title[MAXLINE];
1.234     brouard  1101: char model[MAXLINE]; /**< The model line */
1.217     brouard  1102: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1103: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1104: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1105: char command[FILENAMELENGTH];
                   1106: int  outcmd=0;
                   1107: 
1.217     brouard  1108: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1109: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1110: char filelog[FILENAMELENGTH]; /* Log file */
                   1111: char filerest[FILENAMELENGTH];
                   1112: char fileregp[FILENAMELENGTH];
                   1113: char popfile[FILENAMELENGTH];
                   1114: 
                   1115: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1116: 
1.157     brouard  1117: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1118: /* struct timezone tzp; */
                   1119: /* extern int gettimeofday(); */
                   1120: struct tm tml, *gmtime(), *localtime();
                   1121: 
                   1122: extern time_t time();
                   1123: 
                   1124: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1125: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1126: struct tm tm;
                   1127: 
1.126     brouard  1128: char strcurr[80], strfor[80];
                   1129: 
                   1130: char *endptr;
                   1131: long lval;
                   1132: double dval;
                   1133: 
                   1134: #define NR_END 1
                   1135: #define FREE_ARG char*
                   1136: #define FTOL 1.0e-10
                   1137: 
                   1138: #define NRANSI 
1.240     brouard  1139: #define ITMAX 200
                   1140: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1141: 
                   1142: #define TOL 2.0e-4 
                   1143: 
                   1144: #define CGOLD 0.3819660 
                   1145: #define ZEPS 1.0e-10 
                   1146: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1147: 
                   1148: #define GOLD 1.618034 
                   1149: #define GLIMIT 100.0 
                   1150: #define TINY 1.0e-20 
                   1151: 
                   1152: static double maxarg1,maxarg2;
                   1153: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1154: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1155:   
                   1156: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1157: #define rint(a) floor(a+0.5)
1.166     brouard  1158: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1159: #define mytinydouble 1.0e-16
1.166     brouard  1160: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1161: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1162: /* static double dsqrarg; */
                   1163: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1164: static double sqrarg;
                   1165: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1166: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1167: int agegomp= AGEGOMP;
                   1168: 
                   1169: int imx; 
                   1170: int stepm=1;
                   1171: /* Stepm, step in month: minimum step interpolation*/
                   1172: 
                   1173: int estepm;
                   1174: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1175: 
                   1176: int m,nb;
                   1177: long *num;
1.197     brouard  1178: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1179: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1180:                   covariate for which somebody answered excluding 
                   1181:                   undefined. Usually 2: 0 and 1. */
                   1182: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1183:                             covariate for which somebody answered including 
                   1184:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1185: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1186: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1187: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1188: double *ageexmed,*agecens;
                   1189: double dateintmean=0;
                   1190: 
                   1191: double *weight;
                   1192: int **s; /* Status */
1.141     brouard  1193: double *agedc;
1.145     brouard  1194: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1195:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1196:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1197: double **coqvar; /* Fixed quantitative covariate nqv */
                   1198: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1199: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1200: double  idx; 
                   1201: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1202: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1203: /*k          1  2   3   4     5    6    7     8    9 */
                   1204: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1205: /* Tndvar[k]    1   2   3               4          5 */
                   1206: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1207: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1208: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1209: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1210: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1211: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1212: /* Tprod[i]=k           4               7            */
                   1213: /* Tage[i]=k                  5               8      */
                   1214: /* */
                   1215: /* Type                    */
                   1216: /* V         1  2  3  4  5 */
                   1217: /*           F  F  V  V  V */
                   1218: /*           D  Q  D  D  Q */
                   1219: /*                         */
                   1220: int *TvarsD;
                   1221: int *TvarsDind;
                   1222: int *TvarsQ;
                   1223: int *TvarsQind;
                   1224: 
1.235     brouard  1225: #define MAXRESULTLINES 10
                   1226: int nresult=0;
1.258     brouard  1227: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1228: int TKresult[MAXRESULTLINES];
1.237     brouard  1229: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1230: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1231: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1232: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1233: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1234: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1235: 
1.234     brouard  1236: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1237: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1238: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1239: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1240: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1241: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1242: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1243: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1244: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1245: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1246: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1247: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1248: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1249: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1250: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1251: 
1.230     brouard  1252: int *Tvarsel; /**< Selected covariates for output */
                   1253: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1254: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1255: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1256: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1257: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1258: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1259: int *Tage;
1.227     brouard  1260: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1261: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1262: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1263: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1264: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1265: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1266: int **Tvard;
                   1267: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1268: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1269: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1270:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1271:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1272: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1273: double *lsurv, *lpop, *tpop;
                   1274: 
1.231     brouard  1275: #define FD 1; /* Fixed dummy covariate */
                   1276: #define FQ 2; /* Fixed quantitative covariate */
                   1277: #define FP 3; /* Fixed product covariate */
                   1278: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1279: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1280: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1281: #define VD 10; /* Varying dummy covariate */
                   1282: #define VQ 11; /* Varying quantitative covariate */
                   1283: #define VP 12; /* Varying product covariate */
                   1284: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1285: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1286: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1287: #define APFD 16; /* Age product * fixed dummy covariate */
                   1288: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1289: #define APVD 18; /* Age product * varying dummy covariate */
                   1290: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1291: 
                   1292: #define FTYPE 1; /* Fixed covariate */
                   1293: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1294: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1295: 
                   1296: struct kmodel{
                   1297:        int maintype; /* main type */
                   1298:        int subtype; /* subtype */
                   1299: };
                   1300: struct kmodel modell[NCOVMAX];
                   1301: 
1.143     brouard  1302: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1303: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1304: 
                   1305: /**************** split *************************/
                   1306: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1307: {
                   1308:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1309:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1310:   */ 
                   1311:   char *ss;                            /* pointer */
1.186     brouard  1312:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1313: 
                   1314:   l1 = strlen(path );                  /* length of path */
                   1315:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1316:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1317:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1318:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1319:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1320:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1321:     /* get current working directory */
                   1322:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1323: #ifdef WIN32
                   1324:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1325: #else
                   1326:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1327: #endif
1.126     brouard  1328:       return( GLOCK_ERROR_GETCWD );
                   1329:     }
                   1330:     /* got dirc from getcwd*/
                   1331:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1332:   } else {                             /* strip directory from path */
1.126     brouard  1333:     ss++;                              /* after this, the filename */
                   1334:     l2 = strlen( ss );                 /* length of filename */
                   1335:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1336:     strcpy( name, ss );                /* save file name */
                   1337:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1338:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1339:     printf(" DIRC2 = %s \n",dirc);
                   1340:   }
                   1341:   /* We add a separator at the end of dirc if not exists */
                   1342:   l1 = strlen( dirc );                 /* length of directory */
                   1343:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1344:     dirc[l1] =  DIRSEPARATOR;
                   1345:     dirc[l1+1] = 0; 
                   1346:     printf(" DIRC3 = %s \n",dirc);
                   1347:   }
                   1348:   ss = strrchr( name, '.' );           /* find last / */
                   1349:   if (ss >0){
                   1350:     ss++;
                   1351:     strcpy(ext,ss);                    /* save extension */
                   1352:     l1= strlen( name);
                   1353:     l2= strlen(ss)+1;
                   1354:     strncpy( finame, name, l1-l2);
                   1355:     finame[l1-l2]= 0;
                   1356:   }
                   1357: 
                   1358:   return( 0 );                         /* we're done */
                   1359: }
                   1360: 
                   1361: 
                   1362: /******************************************/
                   1363: 
                   1364: void replace_back_to_slash(char *s, char*t)
                   1365: {
                   1366:   int i;
                   1367:   int lg=0;
                   1368:   i=0;
                   1369:   lg=strlen(t);
                   1370:   for(i=0; i<= lg; i++) {
                   1371:     (s[i] = t[i]);
                   1372:     if (t[i]== '\\') s[i]='/';
                   1373:   }
                   1374: }
                   1375: 
1.132     brouard  1376: char *trimbb(char *out, char *in)
1.137     brouard  1377: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1378:   char *s;
                   1379:   s=out;
                   1380:   while (*in != '\0'){
1.137     brouard  1381:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1382:       in++;
                   1383:     }
                   1384:     *out++ = *in++;
                   1385:   }
                   1386:   *out='\0';
                   1387:   return s;
                   1388: }
                   1389: 
1.187     brouard  1390: /* char *substrchaine(char *out, char *in, char *chain) */
                   1391: /* { */
                   1392: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1393: /*   char *s, *t; */
                   1394: /*   t=in;s=out; */
                   1395: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1396: /*     *out++ = *in++; */
                   1397: /*   } */
                   1398: 
                   1399: /*   /\* *in matches *chain *\/ */
                   1400: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1401: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1402: /*   } */
                   1403: /*   in--; chain--; */
                   1404: /*   while ( (*in != '\0')){ */
                   1405: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1406: /*     *out++ = *in++; */
                   1407: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1408: /*   } */
                   1409: /*   *out='\0'; */
                   1410: /*   out=s; */
                   1411: /*   return out; */
                   1412: /* } */
                   1413: char *substrchaine(char *out, char *in, char *chain)
                   1414: {
                   1415:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1416:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1417: 
                   1418:   char *strloc;
                   1419: 
                   1420:   strcpy (out, in); 
                   1421:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1422:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1423:   if(strloc != NULL){ 
                   1424:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1425:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1426:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1427:   }
                   1428:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1429:   return out;
                   1430: }
                   1431: 
                   1432: 
1.145     brouard  1433: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1434: {
1.187     brouard  1435:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1436:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1437:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1438:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1439:   */
1.160     brouard  1440:   char *s, *t;
1.145     brouard  1441:   t=in;s=in;
                   1442:   while ((*in != occ) && (*in != '\0')){
                   1443:     *alocc++ = *in++;
                   1444:   }
                   1445:   if( *in == occ){
                   1446:     *(alocc)='\0';
                   1447:     s=++in;
                   1448:   }
                   1449:  
                   1450:   if (s == t) {/* occ not found */
                   1451:     *(alocc-(in-s))='\0';
                   1452:     in=s;
                   1453:   }
                   1454:   while ( *in != '\0'){
                   1455:     *blocc++ = *in++;
                   1456:   }
                   1457: 
                   1458:   *blocc='\0';
                   1459:   return t;
                   1460: }
1.137     brouard  1461: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1462: {
1.187     brouard  1463:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1464:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1465:      gives blocc="abcdef2ghi" and alocc="j".
                   1466:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1467:   */
                   1468:   char *s, *t;
                   1469:   t=in;s=in;
                   1470:   while (*in != '\0'){
                   1471:     while( *in == occ){
                   1472:       *blocc++ = *in++;
                   1473:       s=in;
                   1474:     }
                   1475:     *blocc++ = *in++;
                   1476:   }
                   1477:   if (s == t) /* occ not found */
                   1478:     *(blocc-(in-s))='\0';
                   1479:   else
                   1480:     *(blocc-(in-s)-1)='\0';
                   1481:   in=s;
                   1482:   while ( *in != '\0'){
                   1483:     *alocc++ = *in++;
                   1484:   }
                   1485: 
                   1486:   *alocc='\0';
                   1487:   return s;
                   1488: }
                   1489: 
1.126     brouard  1490: int nbocc(char *s, char occ)
                   1491: {
                   1492:   int i,j=0;
                   1493:   int lg=20;
                   1494:   i=0;
                   1495:   lg=strlen(s);
                   1496:   for(i=0; i<= lg; i++) {
1.234     brouard  1497:     if  (s[i] == occ ) j++;
1.126     brouard  1498:   }
                   1499:   return j;
                   1500: }
                   1501: 
1.137     brouard  1502: /* void cutv(char *u,char *v, char*t, char occ) */
                   1503: /* { */
                   1504: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1505: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1506: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1507: /*   int i,lg,j,p=0; */
                   1508: /*   i=0; */
                   1509: /*   lg=strlen(t); */
                   1510: /*   for(j=0; j<=lg-1; j++) { */
                   1511: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1512: /*   } */
1.126     brouard  1513: 
1.137     brouard  1514: /*   for(j=0; j<p; j++) { */
                   1515: /*     (u[j] = t[j]); */
                   1516: /*   } */
                   1517: /*      u[p]='\0'; */
1.126     brouard  1518: 
1.137     brouard  1519: /*    for(j=0; j<= lg; j++) { */
                   1520: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1521: /*   } */
                   1522: /* } */
1.126     brouard  1523: 
1.160     brouard  1524: #ifdef _WIN32
                   1525: char * strsep(char **pp, const char *delim)
                   1526: {
                   1527:   char *p, *q;
                   1528:          
                   1529:   if ((p = *pp) == NULL)
                   1530:     return 0;
                   1531:   if ((q = strpbrk (p, delim)) != NULL)
                   1532:   {
                   1533:     *pp = q + 1;
                   1534:     *q = '\0';
                   1535:   }
                   1536:   else
                   1537:     *pp = 0;
                   1538:   return p;
                   1539: }
                   1540: #endif
                   1541: 
1.126     brouard  1542: /********************** nrerror ********************/
                   1543: 
                   1544: void nrerror(char error_text[])
                   1545: {
                   1546:   fprintf(stderr,"ERREUR ...\n");
                   1547:   fprintf(stderr,"%s\n",error_text);
                   1548:   exit(EXIT_FAILURE);
                   1549: }
                   1550: /*********************** vector *******************/
                   1551: double *vector(int nl, int nh)
                   1552: {
                   1553:   double *v;
                   1554:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1555:   if (!v) nrerror("allocation failure in vector");
                   1556:   return v-nl+NR_END;
                   1557: }
                   1558: 
                   1559: /************************ free vector ******************/
                   1560: void free_vector(double*v, int nl, int nh)
                   1561: {
                   1562:   free((FREE_ARG)(v+nl-NR_END));
                   1563: }
                   1564: 
                   1565: /************************ivector *******************************/
                   1566: int *ivector(long nl,long nh)
                   1567: {
                   1568:   int *v;
                   1569:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1570:   if (!v) nrerror("allocation failure in ivector");
                   1571:   return v-nl+NR_END;
                   1572: }
                   1573: 
                   1574: /******************free ivector **************************/
                   1575: void free_ivector(int *v, long nl, long nh)
                   1576: {
                   1577:   free((FREE_ARG)(v+nl-NR_END));
                   1578: }
                   1579: 
                   1580: /************************lvector *******************************/
                   1581: long *lvector(long nl,long nh)
                   1582: {
                   1583:   long *v;
                   1584:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1585:   if (!v) nrerror("allocation failure in ivector");
                   1586:   return v-nl+NR_END;
                   1587: }
                   1588: 
                   1589: /******************free lvector **************************/
                   1590: void free_lvector(long *v, long nl, long nh)
                   1591: {
                   1592:   free((FREE_ARG)(v+nl-NR_END));
                   1593: }
                   1594: 
                   1595: /******************* imatrix *******************************/
                   1596: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1597:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1598: { 
                   1599:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1600:   int **m; 
                   1601:   
                   1602:   /* allocate pointers to rows */ 
                   1603:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1604:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1605:   m += NR_END; 
                   1606:   m -= nrl; 
                   1607:   
                   1608:   
                   1609:   /* allocate rows and set pointers to them */ 
                   1610:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1611:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1612:   m[nrl] += NR_END; 
                   1613:   m[nrl] -= ncl; 
                   1614:   
                   1615:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1616:   
                   1617:   /* return pointer to array of pointers to rows */ 
                   1618:   return m; 
                   1619: } 
                   1620: 
                   1621: /****************** free_imatrix *************************/
                   1622: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1623:       int **m;
                   1624:       long nch,ncl,nrh,nrl; 
                   1625:      /* free an int matrix allocated by imatrix() */ 
                   1626: { 
                   1627:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1628:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1629: } 
                   1630: 
                   1631: /******************* matrix *******************************/
                   1632: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1633: {
                   1634:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1635:   double **m;
                   1636: 
                   1637:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1638:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1639:   m += NR_END;
                   1640:   m -= nrl;
                   1641: 
                   1642:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1643:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1644:   m[nrl] += NR_END;
                   1645:   m[nrl] -= ncl;
                   1646: 
                   1647:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1648:   return m;
1.145     brouard  1649:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1650: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1651: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1652:    */
                   1653: }
                   1654: 
                   1655: /*************************free matrix ************************/
                   1656: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1657: {
                   1658:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1659:   free((FREE_ARG)(m+nrl-NR_END));
                   1660: }
                   1661: 
                   1662: /******************* ma3x *******************************/
                   1663: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1664: {
                   1665:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1666:   double ***m;
                   1667: 
                   1668:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1669:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1670:   m += NR_END;
                   1671:   m -= nrl;
                   1672: 
                   1673:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1674:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1675:   m[nrl] += NR_END;
                   1676:   m[nrl] -= ncl;
                   1677: 
                   1678:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1679: 
                   1680:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1681:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1682:   m[nrl][ncl] += NR_END;
                   1683:   m[nrl][ncl] -= nll;
                   1684:   for (j=ncl+1; j<=nch; j++) 
                   1685:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1686:   
                   1687:   for (i=nrl+1; i<=nrh; i++) {
                   1688:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1689:     for (j=ncl+1; j<=nch; j++) 
                   1690:       m[i][j]=m[i][j-1]+nlay;
                   1691:   }
                   1692:   return m; 
                   1693:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1694:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1695:   */
                   1696: }
                   1697: 
                   1698: /*************************free ma3x ************************/
                   1699: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1700: {
                   1701:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1702:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1703:   free((FREE_ARG)(m+nrl-NR_END));
                   1704: }
                   1705: 
                   1706: /*************** function subdirf ***********/
                   1707: char *subdirf(char fileres[])
                   1708: {
                   1709:   /* Caution optionfilefiname is hidden */
                   1710:   strcpy(tmpout,optionfilefiname);
                   1711:   strcat(tmpout,"/"); /* Add to the right */
                   1712:   strcat(tmpout,fileres);
                   1713:   return tmpout;
                   1714: }
                   1715: 
                   1716: /*************** function subdirf2 ***********/
                   1717: char *subdirf2(char fileres[], char *preop)
                   1718: {
                   1719:   
                   1720:   /* Caution optionfilefiname is hidden */
                   1721:   strcpy(tmpout,optionfilefiname);
                   1722:   strcat(tmpout,"/");
                   1723:   strcat(tmpout,preop);
                   1724:   strcat(tmpout,fileres);
                   1725:   return tmpout;
                   1726: }
                   1727: 
                   1728: /*************** function subdirf3 ***********/
                   1729: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1730: {
                   1731:   
                   1732:   /* Caution optionfilefiname is hidden */
                   1733:   strcpy(tmpout,optionfilefiname);
                   1734:   strcat(tmpout,"/");
                   1735:   strcat(tmpout,preop);
                   1736:   strcat(tmpout,preop2);
                   1737:   strcat(tmpout,fileres);
                   1738:   return tmpout;
                   1739: }
1.213     brouard  1740:  
                   1741: /*************** function subdirfext ***********/
                   1742: char *subdirfext(char fileres[], char *preop, char *postop)
                   1743: {
                   1744:   
                   1745:   strcpy(tmpout,preop);
                   1746:   strcat(tmpout,fileres);
                   1747:   strcat(tmpout,postop);
                   1748:   return tmpout;
                   1749: }
1.126     brouard  1750: 
1.213     brouard  1751: /*************** function subdirfext3 ***********/
                   1752: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1753: {
                   1754:   
                   1755:   /* Caution optionfilefiname is hidden */
                   1756:   strcpy(tmpout,optionfilefiname);
                   1757:   strcat(tmpout,"/");
                   1758:   strcat(tmpout,preop);
                   1759:   strcat(tmpout,fileres);
                   1760:   strcat(tmpout,postop);
                   1761:   return tmpout;
                   1762: }
                   1763:  
1.162     brouard  1764: char *asc_diff_time(long time_sec, char ascdiff[])
                   1765: {
                   1766:   long sec_left, days, hours, minutes;
                   1767:   days = (time_sec) / (60*60*24);
                   1768:   sec_left = (time_sec) % (60*60*24);
                   1769:   hours = (sec_left) / (60*60) ;
                   1770:   sec_left = (sec_left) %(60*60);
                   1771:   minutes = (sec_left) /60;
                   1772:   sec_left = (sec_left) % (60);
                   1773:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1774:   return ascdiff;
                   1775: }
                   1776: 
1.126     brouard  1777: /***************** f1dim *************************/
                   1778: extern int ncom; 
                   1779: extern double *pcom,*xicom;
                   1780: extern double (*nrfunc)(double []); 
                   1781:  
                   1782: double f1dim(double x) 
                   1783: { 
                   1784:   int j; 
                   1785:   double f;
                   1786:   double *xt; 
                   1787:  
                   1788:   xt=vector(1,ncom); 
                   1789:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1790:   f=(*nrfunc)(xt); 
                   1791:   free_vector(xt,1,ncom); 
                   1792:   return f; 
                   1793: } 
                   1794: 
                   1795: /*****************brent *************************/
                   1796: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1797: {
                   1798:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1799:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1800:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1801:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1802:    * returned function value. 
                   1803:   */
1.126     brouard  1804:   int iter; 
                   1805:   double a,b,d,etemp;
1.159     brouard  1806:   double fu=0,fv,fw,fx;
1.164     brouard  1807:   double ftemp=0.;
1.126     brouard  1808:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1809:   double e=0.0; 
                   1810:  
                   1811:   a=(ax < cx ? ax : cx); 
                   1812:   b=(ax > cx ? ax : cx); 
                   1813:   x=w=v=bx; 
                   1814:   fw=fv=fx=(*f)(x); 
                   1815:   for (iter=1;iter<=ITMAX;iter++) { 
                   1816:     xm=0.5*(a+b); 
                   1817:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1818:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1819:     printf(".");fflush(stdout);
                   1820:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1821: #ifdef DEBUGBRENT
1.126     brouard  1822:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1823:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1824:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1825: #endif
                   1826:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1827:       *xmin=x; 
                   1828:       return fx; 
                   1829:     } 
                   1830:     ftemp=fu;
                   1831:     if (fabs(e) > tol1) { 
                   1832:       r=(x-w)*(fx-fv); 
                   1833:       q=(x-v)*(fx-fw); 
                   1834:       p=(x-v)*q-(x-w)*r; 
                   1835:       q=2.0*(q-r); 
                   1836:       if (q > 0.0) p = -p; 
                   1837:       q=fabs(q); 
                   1838:       etemp=e; 
                   1839:       e=d; 
                   1840:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1841:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1842:       else { 
1.224     brouard  1843:                                d=p/q; 
                   1844:                                u=x+d; 
                   1845:                                if (u-a < tol2 || b-u < tol2) 
                   1846:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1847:       } 
                   1848:     } else { 
                   1849:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1850:     } 
                   1851:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1852:     fu=(*f)(u); 
                   1853:     if (fu <= fx) { 
                   1854:       if (u >= x) a=x; else b=x; 
                   1855:       SHFT(v,w,x,u) 
1.183     brouard  1856:       SHFT(fv,fw,fx,fu) 
                   1857:     } else { 
                   1858:       if (u < x) a=u; else b=u; 
                   1859:       if (fu <= fw || w == x) { 
1.224     brouard  1860:                                v=w; 
                   1861:                                w=u; 
                   1862:                                fv=fw; 
                   1863:                                fw=fu; 
1.183     brouard  1864:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1865:                                v=u; 
                   1866:                                fv=fu; 
1.183     brouard  1867:       } 
                   1868:     } 
1.126     brouard  1869:   } 
                   1870:   nrerror("Too many iterations in brent"); 
                   1871:   *xmin=x; 
                   1872:   return fx; 
                   1873: } 
                   1874: 
                   1875: /****************** mnbrak ***********************/
                   1876: 
                   1877: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1878:            double (*func)(double)) 
1.183     brouard  1879: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1880: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1881: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1882: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1883:    */
1.126     brouard  1884:   double ulim,u,r,q, dum;
                   1885:   double fu; 
1.187     brouard  1886: 
                   1887:   double scale=10.;
                   1888:   int iterscale=0;
                   1889: 
                   1890:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1891:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1892: 
                   1893: 
                   1894:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1895:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1896:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1897:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1898:   /* } */
                   1899: 
1.126     brouard  1900:   if (*fb > *fa) { 
                   1901:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1902:     SHFT(dum,*fb,*fa,dum) 
                   1903:   } 
1.126     brouard  1904:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1905:   *fc=(*func)(*cx); 
1.183     brouard  1906: #ifdef DEBUG
1.224     brouard  1907:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1908:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1909: #endif
1.224     brouard  1910:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1911:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1912:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1913:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1914:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1915:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1916:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1917:       fu=(*func)(u); 
1.163     brouard  1918: #ifdef DEBUG
                   1919:       /* f(x)=A(x-u)**2+f(u) */
                   1920:       double A, fparabu; 
                   1921:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1922:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1923:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1924:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1925:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1926:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1927:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1928:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1929: #endif 
1.184     brouard  1930: #ifdef MNBRAKORIGINAL
1.183     brouard  1931: #else
1.191     brouard  1932: /*       if (fu > *fc) { */
                   1933: /* #ifdef DEBUG */
                   1934: /*       printf("mnbrak4  fu > fc \n"); */
                   1935: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1936: /* #endif */
                   1937: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1938: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1939: /*     dum=u; /\* Shifting c and u *\/ */
                   1940: /*     u = *cx; */
                   1941: /*     *cx = dum; */
                   1942: /*     dum = fu; */
                   1943: /*     fu = *fc; */
                   1944: /*     *fc =dum; */
                   1945: /*       } else { /\* end *\/ */
                   1946: /* #ifdef DEBUG */
                   1947: /*       printf("mnbrak3  fu < fc \n"); */
                   1948: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1949: /* #endif */
                   1950: /*     dum=u; /\* Shifting c and u *\/ */
                   1951: /*     u = *cx; */
                   1952: /*     *cx = dum; */
                   1953: /*     dum = fu; */
                   1954: /*     fu = *fc; */
                   1955: /*     *fc =dum; */
                   1956: /*       } */
1.224     brouard  1957: #ifdef DEBUGMNBRAK
                   1958:                 double A, fparabu; 
                   1959:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1960:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   1961:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   1962:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  1963: #endif
1.191     brouard  1964:       dum=u; /* Shifting c and u */
                   1965:       u = *cx;
                   1966:       *cx = dum;
                   1967:       dum = fu;
                   1968:       fu = *fc;
                   1969:       *fc =dum;
1.183     brouard  1970: #endif
1.162     brouard  1971:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  1972: #ifdef DEBUG
1.224     brouard  1973:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   1974:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  1975: #endif
1.126     brouard  1976:       fu=(*func)(u); 
                   1977:       if (fu < *fc) { 
1.183     brouard  1978: #ifdef DEBUG
1.224     brouard  1979:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1980:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   1981: #endif
                   1982:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   1983:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   1984: #ifdef DEBUG
                   1985:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  1986: #endif
                   1987:       } 
1.162     brouard  1988:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  1989: #ifdef DEBUG
1.224     brouard  1990:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   1991:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  1992: #endif
1.126     brouard  1993:       u=ulim; 
                   1994:       fu=(*func)(u); 
1.183     brouard  1995:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   1996: #ifdef DEBUG
1.224     brouard  1997:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   1998:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  1999: #endif
1.126     brouard  2000:       u=(*cx)+GOLD*(*cx-*bx); 
                   2001:       fu=(*func)(u); 
1.224     brouard  2002: #ifdef DEBUG
                   2003:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2004:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2005: #endif
1.183     brouard  2006:     } /* end tests */
1.126     brouard  2007:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2008:     SHFT(*fa,*fb,*fc,fu) 
                   2009: #ifdef DEBUG
1.224     brouard  2010:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2011:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2012: #endif
                   2013:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2014: } 
                   2015: 
                   2016: /*************** linmin ************************/
1.162     brouard  2017: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2018: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2019: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2020: the value of func at the returned location p . This is actually all accomplished by calling the
                   2021: routines mnbrak and brent .*/
1.126     brouard  2022: int ncom; 
                   2023: double *pcom,*xicom;
                   2024: double (*nrfunc)(double []); 
                   2025:  
1.224     brouard  2026: #ifdef LINMINORIGINAL
1.126     brouard  2027: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2028: #else
                   2029: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2030: #endif
1.126     brouard  2031: { 
                   2032:   double brent(double ax, double bx, double cx, 
                   2033:               double (*f)(double), double tol, double *xmin); 
                   2034:   double f1dim(double x); 
                   2035:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2036:              double *fc, double (*func)(double)); 
                   2037:   int j; 
                   2038:   double xx,xmin,bx,ax; 
                   2039:   double fx,fb,fa;
1.187     brouard  2040: 
1.203     brouard  2041: #ifdef LINMINORIGINAL
                   2042: #else
                   2043:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2044: #endif
                   2045:   
1.126     brouard  2046:   ncom=n; 
                   2047:   pcom=vector(1,n); 
                   2048:   xicom=vector(1,n); 
                   2049:   nrfunc=func; 
                   2050:   for (j=1;j<=n;j++) { 
                   2051:     pcom[j]=p[j]; 
1.202     brouard  2052:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2053:   } 
1.187     brouard  2054: 
1.203     brouard  2055: #ifdef LINMINORIGINAL
                   2056:   xx=1.;
                   2057: #else
                   2058:   axs=0.0;
                   2059:   xxs=1.;
                   2060:   do{
                   2061:     xx= xxs;
                   2062: #endif
1.187     brouard  2063:     ax=0.;
                   2064:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2065:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2066:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2067:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2068:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2069:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2070:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2071: #ifdef LINMINORIGINAL
                   2072: #else
                   2073:     if (fx != fx){
1.224     brouard  2074:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2075:                        printf("|");
                   2076:                        fprintf(ficlog,"|");
1.203     brouard  2077: #ifdef DEBUGLINMIN
1.224     brouard  2078:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2079: #endif
                   2080:     }
1.224     brouard  2081:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2082: #endif
                   2083:   
1.191     brouard  2084: #ifdef DEBUGLINMIN
                   2085:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2086:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2087: #endif
1.224     brouard  2088: #ifdef LINMINORIGINAL
                   2089: #else
                   2090:        if(fb == fx){ /* Flat function in the direction */
                   2091:                xmin=xx;
                   2092:     *flat=1;
                   2093:        }else{
                   2094:     *flat=0;
                   2095: #endif
                   2096:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2097:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2098:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2099:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2100:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2101:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2102: #ifdef DEBUG
1.224     brouard  2103:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2104:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2105: #endif
                   2106: #ifdef LINMINORIGINAL
                   2107: #else
                   2108:                        }
1.126     brouard  2109: #endif
1.191     brouard  2110: #ifdef DEBUGLINMIN
                   2111:   printf("linmin end ");
1.202     brouard  2112:   fprintf(ficlog,"linmin end ");
1.191     brouard  2113: #endif
1.126     brouard  2114:   for (j=1;j<=n;j++) { 
1.203     brouard  2115: #ifdef LINMINORIGINAL
                   2116:     xi[j] *= xmin; 
                   2117: #else
                   2118: #ifdef DEBUGLINMIN
                   2119:     if(xxs <1.0)
                   2120:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2121: #endif
                   2122:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2123: #ifdef DEBUGLINMIN
                   2124:     if(xxs <1.0)
                   2125:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2126: #endif
                   2127: #endif
1.187     brouard  2128:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2129:   } 
1.191     brouard  2130: #ifdef DEBUGLINMIN
1.203     brouard  2131:   printf("\n");
1.191     brouard  2132:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2133:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2134:   for (j=1;j<=n;j++) { 
1.202     brouard  2135:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2136:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2137:     if(j % ncovmodel == 0){
1.191     brouard  2138:       printf("\n");
1.202     brouard  2139:       fprintf(ficlog,"\n");
                   2140:     }
1.191     brouard  2141:   }
1.203     brouard  2142: #else
1.191     brouard  2143: #endif
1.126     brouard  2144:   free_vector(xicom,1,n); 
                   2145:   free_vector(pcom,1,n); 
                   2146: } 
                   2147: 
                   2148: 
                   2149: /*************** powell ************************/
1.162     brouard  2150: /*
                   2151: Minimization of a function func of n variables. Input consists of an initial starting point
                   2152: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2153: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2154: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2155: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2156: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2157:  */
1.224     brouard  2158: #ifdef LINMINORIGINAL
                   2159: #else
                   2160:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2161:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2162: #endif
1.126     brouard  2163: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2164:            double (*func)(double [])) 
                   2165: { 
1.224     brouard  2166: #ifdef LINMINORIGINAL
                   2167:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2168:              double (*func)(double [])); 
1.224     brouard  2169: #else 
1.241     brouard  2170:  void linmin(double p[], double xi[], int n, double *fret,
                   2171:             double (*func)(double []),int *flat); 
1.224     brouard  2172: #endif
1.239     brouard  2173:  int i,ibig,j,jk,k; 
1.126     brouard  2174:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2175:   double directest;
1.126     brouard  2176:   double fp,fptt;
                   2177:   double *xits;
                   2178:   int niterf, itmp;
1.224     brouard  2179: #ifdef LINMINORIGINAL
                   2180: #else
                   2181: 
                   2182:   flatdir=ivector(1,n); 
                   2183:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2184: #endif
1.126     brouard  2185: 
                   2186:   pt=vector(1,n); 
                   2187:   ptt=vector(1,n); 
                   2188:   xit=vector(1,n); 
                   2189:   xits=vector(1,n); 
                   2190:   *fret=(*func)(p); 
                   2191:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2192:   rcurr_time = time(NULL);  
1.126     brouard  2193:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2194:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2195:     ibig=0; 
                   2196:     del=0.0; 
1.157     brouard  2197:     rlast_time=rcurr_time;
                   2198:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2199:     rcurr_time = time(NULL);  
                   2200:     curr_time = *localtime(&rcurr_time);
                   2201:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2202:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2203: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2204:     for (i=1;i<=n;i++) {
1.126     brouard  2205:       fprintf(ficrespow," %.12lf", p[i]);
                   2206:     }
1.239     brouard  2207:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2208:     printf("\n#model=  1      +     age ");
                   2209:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2210:     if(nagesqr==1){
1.241     brouard  2211:        printf("  + age*age  ");
                   2212:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2213:     }
                   2214:     for(j=1;j <=ncovmodel-2;j++){
                   2215:       if(Typevar[j]==0) {
                   2216:        printf("  +      V%d  ",Tvar[j]);
                   2217:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2218:       }else if(Typevar[j]==1) {
                   2219:        printf("  +    V%d*age ",Tvar[j]);
                   2220:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2221:       }else if(Typevar[j]==2) {
                   2222:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2223:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2224:       }
                   2225:     }
1.126     brouard  2226:     printf("\n");
1.239     brouard  2227: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2228: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2229:     fprintf(ficlog,"\n");
1.239     brouard  2230:     for(i=1,jk=1; i <=nlstate; i++){
                   2231:       for(k=1; k <=(nlstate+ndeath); k++){
                   2232:        if (k != i) {
                   2233:          printf("%d%d ",i,k);
                   2234:          fprintf(ficlog,"%d%d ",i,k);
                   2235:          for(j=1; j <=ncovmodel; j++){
                   2236:            printf("%12.7f ",p[jk]);
                   2237:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2238:            jk++; 
                   2239:          }
                   2240:          printf("\n");
                   2241:          fprintf(ficlog,"\n");
                   2242:        }
                   2243:       }
                   2244:     }
1.241     brouard  2245:     if(*iter <=3 && *iter >1){
1.157     brouard  2246:       tml = *localtime(&rcurr_time);
                   2247:       strcpy(strcurr,asctime(&tml));
                   2248:       rforecast_time=rcurr_time; 
1.126     brouard  2249:       itmp = strlen(strcurr);
                   2250:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2251:        strcurr[itmp-1]='\0';
1.162     brouard  2252:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2253:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2254:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2255:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2256:        forecast_time = *localtime(&rforecast_time);
                   2257:        strcpy(strfor,asctime(&forecast_time));
                   2258:        itmp = strlen(strfor);
                   2259:        if(strfor[itmp-1]=='\n')
                   2260:          strfor[itmp-1]='\0';
                   2261:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2262:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2263:       }
                   2264:     }
1.187     brouard  2265:     for (i=1;i<=n;i++) { /* For each direction i */
                   2266:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2267:       fptt=(*fret); 
                   2268: #ifdef DEBUG
1.203     brouard  2269:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2270:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2271: #endif
1.203     brouard  2272:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2273:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2274: #ifdef LINMINORIGINAL
1.188     brouard  2275:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2276: #else
                   2277:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2278:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2279: #endif
                   2280:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2281:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2282:                                /* because that direction will be replaced unless the gain del is small */
                   2283:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2284:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2285:                                /* with the new direction. */
                   2286:                                del=fabs(fptt-(*fret)); 
                   2287:                                ibig=i; 
1.126     brouard  2288:       } 
                   2289: #ifdef DEBUG
                   2290:       printf("%d %.12e",i,(*fret));
                   2291:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2292:       for (j=1;j<=n;j++) {
1.224     brouard  2293:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2294:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2295:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2296:       }
                   2297:       for(j=1;j<=n;j++) {
1.225     brouard  2298:                                printf(" p(%d)=%.12e",j,p[j]);
                   2299:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2300:       }
                   2301:       printf("\n");
                   2302:       fprintf(ficlog,"\n");
                   2303: #endif
1.187     brouard  2304:     } /* end loop on each direction i */
                   2305:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2306:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2307:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2308:       for(j=1;j<=n;j++) {
1.225     brouard  2309:                                if(flatdir[j] >0){
                   2310:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2311:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2312:                                }
                   2313:                                /* printf("\n"); */
                   2314:                                /* fprintf(ficlog,"\n"); */
                   2315:                        }
1.243     brouard  2316:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2317:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2318:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2319:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2320:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2321:       /* decreased of more than 3.84  */
                   2322:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2323:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2324:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2325:                        
1.188     brouard  2326:       /* Starting the program with initial values given by a former maximization will simply change */
                   2327:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2328:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2329:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2330: #ifdef DEBUG
                   2331:       int k[2],l;
                   2332:       k[0]=1;
                   2333:       k[1]=-1;
                   2334:       printf("Max: %.12e",(*func)(p));
                   2335:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2336:       for (j=1;j<=n;j++) {
                   2337:        printf(" %.12e",p[j]);
                   2338:        fprintf(ficlog," %.12e",p[j]);
                   2339:       }
                   2340:       printf("\n");
                   2341:       fprintf(ficlog,"\n");
                   2342:       for(l=0;l<=1;l++) {
                   2343:        for (j=1;j<=n;j++) {
                   2344:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2345:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2346:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2347:        }
                   2348:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2349:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2350:       }
                   2351: #endif
                   2352: 
1.224     brouard  2353: #ifdef LINMINORIGINAL
                   2354: #else
                   2355:       free_ivector(flatdir,1,n); 
                   2356: #endif
1.126     brouard  2357:       free_vector(xit,1,n); 
                   2358:       free_vector(xits,1,n); 
                   2359:       free_vector(ptt,1,n); 
                   2360:       free_vector(pt,1,n); 
                   2361:       return; 
1.192     brouard  2362:     } /* enough precision */ 
1.240     brouard  2363:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2364:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2365:       ptt[j]=2.0*p[j]-pt[j]; 
                   2366:       xit[j]=p[j]-pt[j]; 
                   2367:       pt[j]=p[j]; 
                   2368:     } 
1.181     brouard  2369:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2370: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2371:                if (*iter <=4) {
1.225     brouard  2372: #else
                   2373: #endif
1.224     brouard  2374: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2375: #else
1.161     brouard  2376:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2377: #endif
1.162     brouard  2378:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2379:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2380:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2381:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2382:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2383:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2384:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2385:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2386:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2387:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2388:       /* mu² and del² are equal when f3=f1 */
                   2389:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2390:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2391:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2392:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2393: #ifdef NRCORIGINAL
                   2394:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2395: #else
                   2396:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2397:       t= t- del*SQR(fp-fptt);
1.183     brouard  2398: #endif
1.202     brouard  2399:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2400: #ifdef DEBUG
1.181     brouard  2401:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2402:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2403:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2404:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2405:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2406:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2407:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2408:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2409: #endif
1.183     brouard  2410: #ifdef POWELLORIGINAL
                   2411:       if (t < 0.0) { /* Then we use it for new direction */
                   2412: #else
1.182     brouard  2413:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2414:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2415:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2416:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2417:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2418:       } 
1.181     brouard  2419:       if (directest < 0.0) { /* Then we use it for new direction */
                   2420: #endif
1.191     brouard  2421: #ifdef DEBUGLINMIN
1.234     brouard  2422:        printf("Before linmin in direction P%d-P0\n",n);
                   2423:        for (j=1;j<=n;j++) {
                   2424:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2425:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2426:          if(j % ncovmodel == 0){
                   2427:            printf("\n");
                   2428:            fprintf(ficlog,"\n");
                   2429:          }
                   2430:        }
1.224     brouard  2431: #endif
                   2432: #ifdef LINMINORIGINAL
1.234     brouard  2433:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2434: #else
1.234     brouard  2435:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2436:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2437: #endif
1.234     brouard  2438:        
1.191     brouard  2439: #ifdef DEBUGLINMIN
1.234     brouard  2440:        for (j=1;j<=n;j++) { 
                   2441:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2442:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2443:          if(j % ncovmodel == 0){
                   2444:            printf("\n");
                   2445:            fprintf(ficlog,"\n");
                   2446:          }
                   2447:        }
1.224     brouard  2448: #endif
1.234     brouard  2449:        for (j=1;j<=n;j++) { 
                   2450:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2451:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2452:        }
1.224     brouard  2453: #ifdef LINMINORIGINAL
                   2454: #else
1.234     brouard  2455:        for (j=1, flatd=0;j<=n;j++) {
                   2456:          if(flatdir[j]>0)
                   2457:            flatd++;
                   2458:        }
                   2459:        if(flatd >0){
1.255     brouard  2460:          printf("%d flat directions: ",flatd);
                   2461:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2462:          for (j=1;j<=n;j++) { 
                   2463:            if(flatdir[j]>0){
                   2464:              printf("%d ",j);
                   2465:              fprintf(ficlog,"%d ",j);
                   2466:            }
                   2467:          }
                   2468:          printf("\n");
                   2469:          fprintf(ficlog,"\n");
                   2470:        }
1.191     brouard  2471: #endif
1.234     brouard  2472:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2473:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2474:        
1.126     brouard  2475: #ifdef DEBUG
1.234     brouard  2476:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2477:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2478:        for(j=1;j<=n;j++){
                   2479:          printf(" %lf",xit[j]);
                   2480:          fprintf(ficlog," %lf",xit[j]);
                   2481:        }
                   2482:        printf("\n");
                   2483:        fprintf(ficlog,"\n");
1.126     brouard  2484: #endif
1.192     brouard  2485:       } /* end of t or directest negative */
1.224     brouard  2486: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2487: #else
1.234     brouard  2488:       } /* end if (fptt < fp)  */
1.192     brouard  2489: #endif
1.225     brouard  2490: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2491:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2492: #else
1.224     brouard  2493: #endif
1.234     brouard  2494:                } /* loop iteration */ 
1.126     brouard  2495: } 
1.234     brouard  2496:   
1.126     brouard  2497: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2498:   
1.235     brouard  2499:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2500:   {
1.235     brouard  2501:     /* Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2502:        (and selected quantitative values in nres)
                   2503:        by left multiplying the unit
1.234     brouard  2504:        matrix by transitions matrix until convergence is reached with precision ftolpl */
1.206     brouard  2505:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2506:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2507:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2508:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2509:   /* Initial matrix pimij */
                   2510:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2511:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2512:   /*  0,                   0                  , 1} */
                   2513:   /*
                   2514:    * and after some iteration: */
                   2515:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2516:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2517:   /*  0,                   0                  , 1} */
                   2518:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2519:   /* {0.51571254859325999, 0.4842874514067399, */
                   2520:   /*  0.51326036147820708, 0.48673963852179264} */
                   2521:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2522:     
1.126     brouard  2523:   int i, ii,j,k;
1.209     brouard  2524:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2525:   /* double **matprod2(); */ /* test */
1.218     brouard  2526:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2527:   double **newm;
1.209     brouard  2528:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2529:   int ncvloop=0;
1.169     brouard  2530:   
1.209     brouard  2531:   min=vector(1,nlstate);
                   2532:   max=vector(1,nlstate);
                   2533:   meandiff=vector(1,nlstate);
                   2534: 
1.218     brouard  2535:        /* Starting with matrix unity */
1.126     brouard  2536:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2537:     for (j=1;j<=nlstate+ndeath;j++){
                   2538:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2539:     }
1.169     brouard  2540:   
                   2541:   cov[1]=1.;
                   2542:   
                   2543:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2544:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2545:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2546:     ncvloop++;
1.126     brouard  2547:     newm=savm;
                   2548:     /* Covariates have to be included here again */
1.138     brouard  2549:     cov[2]=agefin;
1.187     brouard  2550:     if(nagesqr==1)
                   2551:       cov[3]= agefin*agefin;;
1.234     brouard  2552:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2553:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2554:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2555:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2556:     }
                   2557:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2558:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2559:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2560:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2561:     }
1.237     brouard  2562:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2563:       if(Dummy[Tvar[Tage[k]]]){
                   2564:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2565:       } else{
1.235     brouard  2566:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2567:       }
1.235     brouard  2568:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2569:     }
1.237     brouard  2570:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2571:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2572:       if(Dummy[Tvard[k][1]==0]){
                   2573:        if(Dummy[Tvard[k][2]==0]){
                   2574:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2575:        }else{
                   2576:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2577:        }
                   2578:       }else{
                   2579:        if(Dummy[Tvard[k][2]==0]){
                   2580:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2581:        }else{
                   2582:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2583:        }
                   2584:       }
1.234     brouard  2585:     }
1.138     brouard  2586:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2587:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2588:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2589:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2590:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2591:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2592:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2593:     
1.126     brouard  2594:     savm=oldm;
                   2595:     oldm=newm;
1.209     brouard  2596: 
                   2597:     for(j=1; j<=nlstate; j++){
                   2598:       max[j]=0.;
                   2599:       min[j]=1.;
                   2600:     }
                   2601:     for(i=1;i<=nlstate;i++){
                   2602:       sumnew=0;
                   2603:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2604:       for(j=1; j<=nlstate; j++){ 
                   2605:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2606:        max[j]=FMAX(max[j],prlim[i][j]);
                   2607:        min[j]=FMIN(min[j],prlim[i][j]);
                   2608:       }
                   2609:     }
                   2610: 
1.126     brouard  2611:     maxmax=0.;
1.209     brouard  2612:     for(j=1; j<=nlstate; j++){
                   2613:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2614:       maxmax=FMAX(maxmax,meandiff[j]);
                   2615:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2616:     } /* j loop */
1.203     brouard  2617:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2618:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2619:     if(maxmax < ftolpl){
1.209     brouard  2620:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2621:       free_vector(min,1,nlstate);
                   2622:       free_vector(max,1,nlstate);
                   2623:       free_vector(meandiff,1,nlstate);
1.126     brouard  2624:       return prlim;
                   2625:     }
1.169     brouard  2626:   } /* age loop */
1.208     brouard  2627:     /* After some age loop it doesn't converge */
1.209     brouard  2628:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2629: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2630:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2631:   free_vector(min,1,nlstate);
                   2632:   free_vector(max,1,nlstate);
                   2633:   free_vector(meandiff,1,nlstate);
1.208     brouard  2634:   
1.169     brouard  2635:   return prlim; /* should not reach here */
1.126     brouard  2636: }
                   2637: 
1.217     brouard  2638: 
                   2639:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2640: 
1.218     brouard  2641:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2642:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2643:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2644: {
1.264     brouard  2645:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2646:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2647:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2648:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2649:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2650:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2651:   /* Initial matrix pimij */
                   2652:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2653:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2654:   /*  0,                   0                  , 1} */
                   2655:   /*
                   2656:    * and after some iteration: */
                   2657:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2658:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2659:   /*  0,                   0                  , 1} */
                   2660:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2661:   /* {0.51571254859325999, 0.4842874514067399, */
                   2662:   /*  0.51326036147820708, 0.48673963852179264} */
                   2663:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2664: 
                   2665:   int i, ii,j,k;
1.247     brouard  2666:   int first=0;
1.217     brouard  2667:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2668:   /* double **matprod2(); */ /* test */
                   2669:   double **out, cov[NCOVMAX+1], **bmij();
                   2670:   double **newm;
1.218     brouard  2671:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2672:   double        **oldm, **savm;  /* for use */
                   2673: 
1.217     brouard  2674:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2675:   int ncvloop=0;
                   2676:   
                   2677:   min=vector(1,nlstate);
                   2678:   max=vector(1,nlstate);
                   2679:   meandiff=vector(1,nlstate);
                   2680: 
1.266     brouard  2681:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2682:   oldm=oldms; savm=savms;
                   2683:   
                   2684:   /* Starting with matrix unity */
                   2685:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2686:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2687:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2688:     }
                   2689:   
                   2690:   cov[1]=1.;
                   2691:   
                   2692:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2693:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2694:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2695:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2696:     ncvloop++;
1.218     brouard  2697:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2698:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2699:     /* Covariates have to be included here again */
                   2700:     cov[2]=agefin;
                   2701:     if(nagesqr==1)
                   2702:       cov[3]= agefin*agefin;;
1.242     brouard  2703:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2704:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2705:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2706:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2707:     }
                   2708:     /* for (k=1; k<=cptcovn;k++) { */
                   2709:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2710:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2711:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2712:     /* } */
                   2713:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2714:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2715:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2716:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2717:     }
                   2718:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2719:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2720:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2721:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2722:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2723:       if(Dummy[Tvar[Tage[k]]]){
                   2724:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2725:       } else{
                   2726:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2727:       }
                   2728:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2729:     }
                   2730:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2731:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2732:       if(Dummy[Tvard[k][1]==0]){
                   2733:        if(Dummy[Tvard[k][2]==0]){
                   2734:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2735:        }else{
                   2736:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2737:        }
                   2738:       }else{
                   2739:        if(Dummy[Tvard[k][2]==0]){
                   2740:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2741:        }else{
                   2742:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2743:        }
                   2744:       }
1.217     brouard  2745:     }
                   2746:     
                   2747:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2748:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2749:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2750:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2751:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2752:                /* ij should be linked to the correct index of cov */
                   2753:                /* age and covariate values ij are in 'cov', but we need to pass
                   2754:                 * ij for the observed prevalence at age and status and covariate
                   2755:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2756:                 */
                   2757:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2758:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2759:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2760:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2761:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2762:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2763:     /*         printf("%d newm= ",i); */
                   2764:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2765:     /*           printf("%f ",newm[i][j]); */
                   2766:     /*         } */
                   2767:     /*         printf("oldm * "); */
                   2768:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2769:     /*           printf("%f ",oldm[i][j]); */
                   2770:     /*         } */
1.268     brouard  2771:     /*         printf(" bmmij "); */
1.266     brouard  2772:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2773:     /*           printf("%f ",pmmij[i][j]); */
                   2774:     /*         } */
                   2775:     /*         printf("\n"); */
                   2776:     /*   } */
                   2777:     /* } */
1.217     brouard  2778:     savm=oldm;
                   2779:     oldm=newm;
1.266     brouard  2780: 
1.217     brouard  2781:     for(j=1; j<=nlstate; j++){
                   2782:       max[j]=0.;
                   2783:       min[j]=1.;
                   2784:     }
                   2785:     for(j=1; j<=nlstate; j++){ 
                   2786:       for(i=1;i<=nlstate;i++){
1.234     brouard  2787:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2788:        bprlim[i][j]= newm[i][j];
                   2789:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2790:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2791:       }
                   2792:     }
1.218     brouard  2793:                
1.217     brouard  2794:     maxmax=0.;
                   2795:     for(i=1; i<=nlstate; i++){
                   2796:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2797:       maxmax=FMAX(maxmax,meandiff[i]);
                   2798:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2799:     } /* i loop */
1.217     brouard  2800:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2801:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2802:     if(maxmax < ftolpl){
1.220     brouard  2803:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2804:       free_vector(min,1,nlstate);
                   2805:       free_vector(max,1,nlstate);
                   2806:       free_vector(meandiff,1,nlstate);
                   2807:       return bprlim;
                   2808:     }
                   2809:   } /* age loop */
                   2810:     /* After some age loop it doesn't converge */
1.247     brouard  2811:   if(first){
                   2812:     first=1;
                   2813:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2814: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2815:   }
                   2816:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2817: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2818:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2819:   free_vector(min,1,nlstate);
                   2820:   free_vector(max,1,nlstate);
                   2821:   free_vector(meandiff,1,nlstate);
                   2822:   
                   2823:   return bprlim; /* should not reach here */
                   2824: }
                   2825: 
1.126     brouard  2826: /*************** transition probabilities ***************/ 
                   2827: 
                   2828: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2829: {
1.138     brouard  2830:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2831:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2832:      model to the ncovmodel covariates (including constant and age).
                   2833:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2834:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2835:      ncth covariate in the global vector x is given by the formula:
                   2836:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2837:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2838:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2839:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2840:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2841:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2842:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2843:   */
                   2844:   double s1, lnpijopii;
1.126     brouard  2845:   /*double t34;*/
1.164     brouard  2846:   int i,j, nc, ii, jj;
1.126     brouard  2847: 
1.223     brouard  2848:   for(i=1; i<= nlstate; i++){
                   2849:     for(j=1; j<i;j++){
                   2850:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2851:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2852:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2853:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2854:       }
                   2855:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2856:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2857:     }
                   2858:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2859:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2860:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2861:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2862:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2863:       }
                   2864:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2865:     }
                   2866:   }
1.218     brouard  2867:   
1.223     brouard  2868:   for(i=1; i<= nlstate; i++){
                   2869:     s1=0;
                   2870:     for(j=1; j<i; j++){
                   2871:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2872:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2873:     }
                   2874:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2875:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2876:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2877:     }
                   2878:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2879:     ps[i][i]=1./(s1+1.);
                   2880:     /* Computing other pijs */
                   2881:     for(j=1; j<i; j++)
                   2882:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2883:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2884:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2885:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2886:   } /* end i */
1.218     brouard  2887:   
1.223     brouard  2888:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2889:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2890:       ps[ii][jj]=0;
                   2891:       ps[ii][ii]=1;
                   2892:     }
                   2893:   }
1.218     brouard  2894:   
                   2895:   
1.223     brouard  2896:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2897:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2898:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2899:   /*   } */
                   2900:   /*   printf("\n "); */
                   2901:   /* } */
                   2902:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2903:   /*
                   2904:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2905:                goto end;*/
1.266     brouard  2906:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2907: }
                   2908: 
1.218     brouard  2909: /*************** backward transition probabilities ***************/ 
                   2910: 
                   2911:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2912: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2913:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2914: {
1.266     brouard  2915:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2916:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2917:    */
1.218     brouard  2918:   int i, ii, j,k;
1.222     brouard  2919:   
                   2920:   double **out, **pmij();
                   2921:   double sumnew=0.;
1.218     brouard  2922:   double agefin;
1.268     brouard  2923:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2924:   double **dnewm, **dsavm, **doldm;
                   2925:   double **bbmij;
                   2926:   
1.218     brouard  2927:   doldm=ddoldms; /* global pointers */
1.222     brouard  2928:   dnewm=ddnewms;
                   2929:   dsavm=ddsavms;
                   2930:   
                   2931:   agefin=cov[2];
1.268     brouard  2932:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2933:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2934:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2935:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2936: 
                   2937:   /* P_x */
1.266     brouard  2938:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2939:   /* outputs pmmij which is a stochastic matrix in row */
                   2940: 
                   2941:   /* Diag(w_x) */
                   2942:   /* Problem with prevacurrent which can be zero */
                   2943:   sumnew=0.;
1.269     brouard  2944:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2945:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2946:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2947:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2948:   }
                   2949:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2950:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2951:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2952:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2953:     }
                   2954:   }else{
                   2955:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2956:       for (j=1;j<=nlstate+ndeath;j++)
                   2957:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   2958:     }
                   2959:     /* if(sumnew <0.9){ */
                   2960:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   2961:     /* } */
                   2962:   }
                   2963:   k3=0.0;  /* We put the last diagonal to 0 */
                   2964:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   2965:       doldm[ii][ii]= k3;
                   2966:   }
                   2967:   /* End doldm, At the end doldm is diag[(w_i)] */
                   2968:   
                   2969:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   2970:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   2971: 
                   2972:   /* Diag(Sum_i w^i_x p^ij_x */
                   2973:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  2974:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  2975:     sumnew=0.;
1.222     brouard  2976:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  2977:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  2978:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  2979:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  2980:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  2981:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  2982:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2983:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  2984:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  2985:        /* }else */
1.268     brouard  2986:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   2987:     } /*End ii */
                   2988:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   2989: 
                   2990:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   2991:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  2992:   /* end bmij */
1.266     brouard  2993:   return ps; /*pointer is unchanged */
1.218     brouard  2994: }
1.217     brouard  2995: /*************** transition probabilities ***************/ 
                   2996: 
1.218     brouard  2997: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  2998: {
                   2999:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3000:      computes the probability to be observed in state j being in state i by appying the
                   3001:      model to the ncovmodel covariates (including constant and age).
                   3002:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3003:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3004:      ncth covariate in the global vector x is given by the formula:
                   3005:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3006:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3007:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3008:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3009:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3010:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3011:   */
                   3012:   double s1, lnpijopii;
                   3013:   /*double t34;*/
                   3014:   int i,j, nc, ii, jj;
                   3015: 
1.234     brouard  3016:   for(i=1; i<= nlstate; i++){
                   3017:     for(j=1; j<i;j++){
                   3018:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3019:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3020:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3021:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3022:       }
                   3023:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3024:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3025:     }
                   3026:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3027:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3028:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3029:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3030:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3031:       }
                   3032:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3033:     }
                   3034:   }
                   3035:   
                   3036:   for(i=1; i<= nlstate; i++){
                   3037:     s1=0;
                   3038:     for(j=1; j<i; j++){
                   3039:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3040:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3041:     }
                   3042:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3043:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3044:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3045:     }
                   3046:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3047:     ps[i][i]=1./(s1+1.);
                   3048:     /* Computing other pijs */
                   3049:     for(j=1; j<i; j++)
                   3050:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3051:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3052:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3053:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3054:   } /* end i */
                   3055:   
                   3056:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3057:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3058:       ps[ii][jj]=0;
                   3059:       ps[ii][ii]=1;
                   3060:     }
                   3061:   }
                   3062:   /* Added for backcast */ /* Transposed matrix too */
                   3063:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3064:     s1=0.;
                   3065:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3066:       s1+=ps[ii][jj];
                   3067:     }
                   3068:     for(ii=1; ii<= nlstate; ii++){
                   3069:       ps[ii][jj]=ps[ii][jj]/s1;
                   3070:     }
                   3071:   }
                   3072:   /* Transposition */
                   3073:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3074:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3075:       s1=ps[ii][jj];
                   3076:       ps[ii][jj]=ps[jj][ii];
                   3077:       ps[jj][ii]=s1;
                   3078:     }
                   3079:   }
                   3080:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3081:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3082:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3083:   /*   } */
                   3084:   /*   printf("\n "); */
                   3085:   /* } */
                   3086:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3087:   /*
                   3088:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3089:     goto end;*/
                   3090:   return ps;
1.217     brouard  3091: }
                   3092: 
                   3093: 
1.126     brouard  3094: /**************** Product of 2 matrices ******************/
                   3095: 
1.145     brouard  3096: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3097: {
                   3098:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3099:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3100:   /* in, b, out are matrice of pointers which should have been initialized 
                   3101:      before: only the contents of out is modified. The function returns
                   3102:      a pointer to pointers identical to out */
1.145     brouard  3103:   int i, j, k;
1.126     brouard  3104:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3105:     for(k=ncolol; k<=ncoloh; k++){
                   3106:       out[i][k]=0.;
                   3107:       for(j=ncl; j<=nch; j++)
                   3108:        out[i][k] +=in[i][j]*b[j][k];
                   3109:     }
1.126     brouard  3110:   return out;
                   3111: }
                   3112: 
                   3113: 
                   3114: /************* Higher Matrix Product ***************/
                   3115: 
1.235     brouard  3116: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3117: {
1.218     brouard  3118:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3119:      'nhstepm*hstepm*stepm' months (i.e. until
                   3120:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3121:      nhstepm*hstepm matrices. 
                   3122:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3123:      (typically every 2 years instead of every month which is too big 
                   3124:      for the memory).
                   3125:      Model is determined by parameters x and covariates have to be 
                   3126:      included manually here. 
                   3127: 
                   3128:      */
                   3129: 
                   3130:   int i, j, d, h, k;
1.131     brouard  3131:   double **out, cov[NCOVMAX+1];
1.126     brouard  3132:   double **newm;
1.187     brouard  3133:   double agexact;
1.214     brouard  3134:   double agebegin, ageend;
1.126     brouard  3135: 
                   3136:   /* Hstepm could be zero and should return the unit matrix */
                   3137:   for (i=1;i<=nlstate+ndeath;i++)
                   3138:     for (j=1;j<=nlstate+ndeath;j++){
                   3139:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3140:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3141:     }
                   3142:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3143:   for(h=1; h <=nhstepm; h++){
                   3144:     for(d=1; d <=hstepm; d++){
                   3145:       newm=savm;
                   3146:       /* Covariates have to be included here again */
                   3147:       cov[1]=1.;
1.214     brouard  3148:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3149:       cov[2]=agexact;
                   3150:       if(nagesqr==1)
1.227     brouard  3151:        cov[3]= agexact*agexact;
1.235     brouard  3152:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3153:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3154:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3155:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3156:       }
                   3157:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3158:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3159:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3160:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3161:       }
                   3162:       for (k=1; k<=cptcovage;k++){
                   3163:        if(Dummy[Tvar[Tage[k]]]){
                   3164:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3165:        } else{
                   3166:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3167:        }
                   3168:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3169:       }
                   3170:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3171:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3172:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3173:       }
                   3174:       /* for (k=1; k<=cptcovn;k++)  */
                   3175:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3176:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3177:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3178:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3179:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3180:       
                   3181:       
1.126     brouard  3182:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3183:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3184:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3185:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3186:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3187:       /* if((int)age == 70){ */
                   3188:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3189:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3190:       /*         printf("%d pmmij ",i); */
                   3191:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3192:       /*           printf("%f ",pmmij[i][j]); */
                   3193:       /*         } */
                   3194:       /*         printf(" oldm "); */
                   3195:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3196:       /*           printf("%f ",oldm[i][j]); */
                   3197:       /*         } */
                   3198:       /*         printf("\n"); */
                   3199:       /*       } */
                   3200:       /* } */
1.126     brouard  3201:       savm=oldm;
                   3202:       oldm=newm;
                   3203:     }
                   3204:     for(i=1; i<=nlstate+ndeath; i++)
                   3205:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3206:        po[i][j][h]=newm[i][j];
                   3207:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3208:       }
1.128     brouard  3209:     /*printf("h=%d ",h);*/
1.126     brouard  3210:   } /* end h */
1.267     brouard  3211:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3212:   return po;
                   3213: }
                   3214: 
1.217     brouard  3215: /************* Higher Back Matrix Product ***************/
1.218     brouard  3216: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3217: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3218: {
1.266     brouard  3219:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3220:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3221:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3222:      nhstepm*hstepm matrices.
                   3223:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3224:      (typically every 2 years instead of every month which is too big
1.217     brouard  3225:      for the memory).
1.218     brouard  3226:      Model is determined by parameters x and covariates have to be
1.266     brouard  3227:      included manually here. Then we use a call to bmij(x and cov)
                   3228:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3229:   */
1.217     brouard  3230: 
                   3231:   int i, j, d, h, k;
1.266     brouard  3232:   double **out, cov[NCOVMAX+1], **bmij();
                   3233:   double **newm, ***newmm;
1.217     brouard  3234:   double agexact;
                   3235:   double agebegin, ageend;
1.222     brouard  3236:   double **oldm, **savm;
1.217     brouard  3237: 
1.266     brouard  3238:   newmm=po; /* To be saved */
                   3239:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3240:   /* Hstepm could be zero and should return the unit matrix */
                   3241:   for (i=1;i<=nlstate+ndeath;i++)
                   3242:     for (j=1;j<=nlstate+ndeath;j++){
                   3243:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3244:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3245:     }
                   3246:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3247:   for(h=1; h <=nhstepm; h++){
                   3248:     for(d=1; d <=hstepm; d++){
                   3249:       newm=savm;
                   3250:       /* Covariates have to be included here again */
                   3251:       cov[1]=1.;
1.271     brouard  3252:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3253:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3254:       cov[2]=agexact;
                   3255:       if(nagesqr==1)
1.222     brouard  3256:        cov[3]= agexact*agexact;
1.266     brouard  3257:       for (k=1; k<=cptcovn;k++){
                   3258:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3259:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3260:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3261:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3262:       }
1.267     brouard  3263:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3264:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3265:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3266:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3267:       }
                   3268:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3269:        if(Dummy[Tvar[Tage[k]]]){
                   3270:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3271:        } else{
                   3272:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3273:        }
                   3274:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3275:       }
                   3276:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3277:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3278:       }                        
1.217     brouard  3279:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3280:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3281: 
1.218     brouard  3282:       /* Careful transposed matrix */
1.266     brouard  3283:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3284:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3285:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3286:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3287:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3288:       /* if((int)age == 70){ */
                   3289:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3290:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3291:       /*         printf("%d pmmij ",i); */
                   3292:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3293:       /*           printf("%f ",pmmij[i][j]); */
                   3294:       /*         } */
                   3295:       /*         printf(" oldm "); */
                   3296:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3297:       /*           printf("%f ",oldm[i][j]); */
                   3298:       /*         } */
                   3299:       /*         printf("\n"); */
                   3300:       /*       } */
                   3301:       /* } */
                   3302:       savm=oldm;
                   3303:       oldm=newm;
                   3304:     }
                   3305:     for(i=1; i<=nlstate+ndeath; i++)
                   3306:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3307:        po[i][j][h]=newm[i][j];
1.268     brouard  3308:        /* if(h==nhstepm) */
                   3309:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3310:       }
1.268     brouard  3311:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3312:   } /* end h */
1.268     brouard  3313:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3314:   return po;
                   3315: }
                   3316: 
                   3317: 
1.162     brouard  3318: #ifdef NLOPT
                   3319:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3320:   double fret;
                   3321:   double *xt;
                   3322:   int j;
                   3323:   myfunc_data *d2 = (myfunc_data *) pd;
                   3324: /* xt = (p1-1); */
                   3325:   xt=vector(1,n); 
                   3326:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3327: 
                   3328:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3329:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3330:   printf("Function = %.12lf ",fret);
                   3331:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3332:   printf("\n");
                   3333:  free_vector(xt,1,n);
                   3334:   return fret;
                   3335: }
                   3336: #endif
1.126     brouard  3337: 
                   3338: /*************** log-likelihood *************/
                   3339: double func( double *x)
                   3340: {
1.226     brouard  3341:   int i, ii, j, k, mi, d, kk;
                   3342:   int ioffset=0;
                   3343:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3344:   double **out;
                   3345:   double lli; /* Individual log likelihood */
                   3346:   int s1, s2;
1.228     brouard  3347:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3348:   double bbh, survp;
                   3349:   long ipmx;
                   3350:   double agexact;
                   3351:   /*extern weight */
                   3352:   /* We are differentiating ll according to initial status */
                   3353:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3354:   /*for(i=1;i<imx;i++) 
                   3355:     printf(" %d\n",s[4][i]);
                   3356:   */
1.162     brouard  3357: 
1.226     brouard  3358:   ++countcallfunc;
1.162     brouard  3359: 
1.226     brouard  3360:   cov[1]=1.;
1.126     brouard  3361: 
1.226     brouard  3362:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3363:   ioffset=0;
1.226     brouard  3364:   if(mle==1){
                   3365:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3366:       /* Computes the values of the ncovmodel covariates of the model
                   3367:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3368:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3369:         to be observed in j being in i according to the model.
                   3370:       */
1.243     brouard  3371:       ioffset=2+nagesqr ;
1.233     brouard  3372:    /* Fixed */
1.234     brouard  3373:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3374:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3375:       }
1.226     brouard  3376:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3377:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3378:         has been calculated etc */
                   3379:       /* For an individual i, wav[i] gives the number of effective waves */
                   3380:       /* We compute the contribution to Likelihood of each effective transition
                   3381:         mw[mi][i] is real wave of the mi th effectve wave */
                   3382:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3383:         s2=s[mw[mi+1][i]][i];
                   3384:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3385:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3386:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3387:       */
                   3388:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3389:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3390:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3391:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3392:        }
                   3393:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3394:          for (j=1;j<=nlstate+ndeath;j++){
                   3395:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3396:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3397:          }
                   3398:        for(d=0; d<dh[mi][i]; d++){
                   3399:          newm=savm;
                   3400:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3401:          cov[2]=agexact;
                   3402:          if(nagesqr==1)
                   3403:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3404:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3405:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3406:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3407:          else
                   3408:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3409:          }
                   3410:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3411:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3412:          savm=oldm;
                   3413:          oldm=newm;
                   3414:        } /* end mult */
                   3415:        
                   3416:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3417:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3418:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3419:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3420:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3421:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3422:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3423:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3424:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3425:                                 * -stepm/2 to stepm/2 .
                   3426:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3427:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3428:                                 */
1.234     brouard  3429:        s1=s[mw[mi][i]][i];
                   3430:        s2=s[mw[mi+1][i]][i];
                   3431:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3432:        /* bias bh is positive if real duration
                   3433:         * is higher than the multiple of stepm and negative otherwise.
                   3434:         */
                   3435:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3436:        if( s2 > nlstate){ 
                   3437:          /* i.e. if s2 is a death state and if the date of death is known 
                   3438:             then the contribution to the likelihood is the probability to 
                   3439:             die between last step unit time and current  step unit time, 
                   3440:             which is also equal to probability to die before dh 
                   3441:             minus probability to die before dh-stepm . 
                   3442:             In version up to 0.92 likelihood was computed
                   3443:             as if date of death was unknown. Death was treated as any other
                   3444:             health state: the date of the interview describes the actual state
                   3445:             and not the date of a change in health state. The former idea was
                   3446:             to consider that at each interview the state was recorded
                   3447:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3448:             introduced the exact date of death then we should have modified
                   3449:             the contribution of an exact death to the likelihood. This new
                   3450:             contribution is smaller and very dependent of the step unit
                   3451:             stepm. It is no more the probability to die between last interview
                   3452:             and month of death but the probability to survive from last
                   3453:             interview up to one month before death multiplied by the
                   3454:             probability to die within a month. Thanks to Chris
                   3455:             Jackson for correcting this bug.  Former versions increased
                   3456:             mortality artificially. The bad side is that we add another loop
                   3457:             which slows down the processing. The difference can be up to 10%
                   3458:             lower mortality.
                   3459:          */
                   3460:          /* If, at the beginning of the maximization mostly, the
                   3461:             cumulative probability or probability to be dead is
                   3462:             constant (ie = 1) over time d, the difference is equal to
                   3463:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3464:             s1 at precedent wave, to be dead a month before current
                   3465:             wave is equal to probability, being at state s1 at
                   3466:             precedent wave, to be dead at mont of the current
                   3467:             wave. Then the observed probability (that this person died)
                   3468:             is null according to current estimated parameter. In fact,
                   3469:             it should be very low but not zero otherwise the log go to
                   3470:             infinity.
                   3471:          */
1.183     brouard  3472: /* #ifdef INFINITYORIGINAL */
                   3473: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3474: /* #else */
                   3475: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3476: /*         lli=log(mytinydouble); */
                   3477: /*       else */
                   3478: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3479: /* #endif */
1.226     brouard  3480:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3481:          
1.226     brouard  3482:        } else if  ( s2==-1 ) { /* alive */
                   3483:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3484:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3485:          /*survp += out[s1][j]; */
                   3486:          lli= log(survp);
                   3487:        }
                   3488:        else if  (s2==-4) { 
                   3489:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3490:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3491:          lli= log(survp); 
                   3492:        } 
                   3493:        else if  (s2==-5) { 
                   3494:          for (j=1,survp=0. ; j<=2; j++)  
                   3495:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3496:          lli= log(survp); 
                   3497:        } 
                   3498:        else{
                   3499:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3500:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3501:        } 
                   3502:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3503:        /*if(lli ==000.0)*/
                   3504:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3505:        ipmx +=1;
                   3506:        sw += weight[i];
                   3507:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3508:        /* if (lli < log(mytinydouble)){ */
                   3509:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3510:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3511:        /* } */
                   3512:       } /* end of wave */
                   3513:     } /* end of individual */
                   3514:   }  else if(mle==2){
                   3515:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3516:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3517:       for(mi=1; mi<= wav[i]-1; mi++){
                   3518:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3519:          for (j=1;j<=nlstate+ndeath;j++){
                   3520:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3521:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3522:          }
                   3523:        for(d=0; d<=dh[mi][i]; d++){
                   3524:          newm=savm;
                   3525:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3526:          cov[2]=agexact;
                   3527:          if(nagesqr==1)
                   3528:            cov[3]= agexact*agexact;
                   3529:          for (kk=1; kk<=cptcovage;kk++) {
                   3530:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3531:          }
                   3532:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3533:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3534:          savm=oldm;
                   3535:          oldm=newm;
                   3536:        } /* end mult */
                   3537:       
                   3538:        s1=s[mw[mi][i]][i];
                   3539:        s2=s[mw[mi+1][i]][i];
                   3540:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3541:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3542:        ipmx +=1;
                   3543:        sw += weight[i];
                   3544:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3545:       } /* end of wave */
                   3546:     } /* end of individual */
                   3547:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3548:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3549:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3550:       for(mi=1; mi<= wav[i]-1; mi++){
                   3551:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3552:          for (j=1;j<=nlstate+ndeath;j++){
                   3553:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3554:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3555:          }
                   3556:        for(d=0; d<dh[mi][i]; d++){
                   3557:          newm=savm;
                   3558:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3559:          cov[2]=agexact;
                   3560:          if(nagesqr==1)
                   3561:            cov[3]= agexact*agexact;
                   3562:          for (kk=1; kk<=cptcovage;kk++) {
                   3563:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3564:          }
                   3565:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3566:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3567:          savm=oldm;
                   3568:          oldm=newm;
                   3569:        } /* end mult */
                   3570:       
                   3571:        s1=s[mw[mi][i]][i];
                   3572:        s2=s[mw[mi+1][i]][i];
                   3573:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3574:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3575:        ipmx +=1;
                   3576:        sw += weight[i];
                   3577:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3578:       } /* end of wave */
                   3579:     } /* end of individual */
                   3580:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3581:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3582:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3583:       for(mi=1; mi<= wav[i]-1; mi++){
                   3584:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3585:          for (j=1;j<=nlstate+ndeath;j++){
                   3586:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3587:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3588:          }
                   3589:        for(d=0; d<dh[mi][i]; d++){
                   3590:          newm=savm;
                   3591:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3592:          cov[2]=agexact;
                   3593:          if(nagesqr==1)
                   3594:            cov[3]= agexact*agexact;
                   3595:          for (kk=1; kk<=cptcovage;kk++) {
                   3596:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3597:          }
1.126     brouard  3598:        
1.226     brouard  3599:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3600:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3601:          savm=oldm;
                   3602:          oldm=newm;
                   3603:        } /* end mult */
                   3604:       
                   3605:        s1=s[mw[mi][i]][i];
                   3606:        s2=s[mw[mi+1][i]][i];
                   3607:        if( s2 > nlstate){ 
                   3608:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3609:        } else if  ( s2==-1 ) { /* alive */
                   3610:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3611:            survp += out[s1][j];
                   3612:          lli= log(survp);
                   3613:        }else{
                   3614:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3615:        }
                   3616:        ipmx +=1;
                   3617:        sw += weight[i];
                   3618:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3619: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3620:       } /* end of wave */
                   3621:     } /* end of individual */
                   3622:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3623:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3624:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3625:       for(mi=1; mi<= wav[i]-1; mi++){
                   3626:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3627:          for (j=1;j<=nlstate+ndeath;j++){
                   3628:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3629:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3630:          }
                   3631:        for(d=0; d<dh[mi][i]; d++){
                   3632:          newm=savm;
                   3633:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3634:          cov[2]=agexact;
                   3635:          if(nagesqr==1)
                   3636:            cov[3]= agexact*agexact;
                   3637:          for (kk=1; kk<=cptcovage;kk++) {
                   3638:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3639:          }
1.126     brouard  3640:        
1.226     brouard  3641:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3642:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3643:          savm=oldm;
                   3644:          oldm=newm;
                   3645:        } /* end mult */
                   3646:       
                   3647:        s1=s[mw[mi][i]][i];
                   3648:        s2=s[mw[mi+1][i]][i];
                   3649:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3650:        ipmx +=1;
                   3651:        sw += weight[i];
                   3652:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3653:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3654:       } /* end of wave */
                   3655:     } /* end of individual */
                   3656:   } /* End of if */
                   3657:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3658:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3659:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3660:   return -l;
1.126     brouard  3661: }
                   3662: 
                   3663: /*************** log-likelihood *************/
                   3664: double funcone( double *x)
                   3665: {
1.228     brouard  3666:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3667:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3668:   int ioffset=0;
1.131     brouard  3669:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3670:   double **out;
                   3671:   double lli; /* Individual log likelihood */
                   3672:   double llt;
                   3673:   int s1, s2;
1.228     brouard  3674:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3675: 
1.126     brouard  3676:   double bbh, survp;
1.187     brouard  3677:   double agexact;
1.214     brouard  3678:   double agebegin, ageend;
1.126     brouard  3679:   /*extern weight */
                   3680:   /* We are differentiating ll according to initial status */
                   3681:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3682:   /*for(i=1;i<imx;i++) 
                   3683:     printf(" %d\n",s[4][i]);
                   3684:   */
                   3685:   cov[1]=1.;
                   3686: 
                   3687:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3688:   ioffset=0;
                   3689:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3690:     /* ioffset=2+nagesqr+cptcovage; */
                   3691:     ioffset=2+nagesqr;
1.232     brouard  3692:     /* Fixed */
1.224     brouard  3693:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3694:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3695:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3696:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3697: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3698: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3699: /*    cov[2+6]=covar[2][i]; V2  */
                   3700: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3701: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3702: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3703: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3704: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3705: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3706:     }
1.232     brouard  3707:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3708:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3709:     /* } */
1.231     brouard  3710:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3711:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3712:     /* } */
1.225     brouard  3713:     
1.233     brouard  3714: 
                   3715:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3716:     /* Wave varying (but not age varying) */
                   3717:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3718:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3719:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3720:       }
1.232     brouard  3721:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3722:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3723:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3724:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3725:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3726:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3727:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3728:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3729:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3730:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3731:       /* } */
1.126     brouard  3732:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3733:        for (j=1;j<=nlstate+ndeath;j++){
                   3734:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3735:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3736:        }
1.214     brouard  3737:       
                   3738:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3739:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3740:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3741:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3742:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3743:          and mw[mi+1][i]. dh depends on stepm.*/
                   3744:        newm=savm;
1.247     brouard  3745:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3746:        cov[2]=agexact;
                   3747:        if(nagesqr==1)
                   3748:          cov[3]= agexact*agexact;
                   3749:        for (kk=1; kk<=cptcovage;kk++) {
                   3750:          if(!FixedV[Tvar[Tage[kk]]])
                   3751:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3752:          else
                   3753:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3754:        }
                   3755:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3756:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3757:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3758:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3759:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3760:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3761:        savm=oldm;
                   3762:        oldm=newm;
1.126     brouard  3763:       } /* end mult */
                   3764:       
                   3765:       s1=s[mw[mi][i]][i];
                   3766:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3767:       /* if(s2==-1){ */
1.268     brouard  3768:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3769:       /*       /\* exit(1); *\/ */
                   3770:       /* } */
1.126     brouard  3771:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3772:       /* bias is positive if real duration
                   3773:        * is higher than the multiple of stepm and negative otherwise.
                   3774:        */
                   3775:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3776:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3777:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3778:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3779:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3780:        lli= log(survp);
1.126     brouard  3781:       }else if (mle==1){
1.242     brouard  3782:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3783:       } else if(mle==2){
1.242     brouard  3784:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3785:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3786:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3787:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3788:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3789:       } else{  /* mle=0 back to 1 */
1.242     brouard  3790:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3791:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3792:       } /* End of if */
                   3793:       ipmx +=1;
                   3794:       sw += weight[i];
                   3795:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3796:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3797:       if(globpr){
1.246     brouard  3798:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3799:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3800:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3801:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3802:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3803:          llt +=ll[k]*gipmx/gsw;
                   3804:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3805:        }
                   3806:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3807:       }
1.232     brouard  3808:        } /* end of wave */
                   3809: } /* end of individual */
                   3810: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3811: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3812: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3813: if(globpr==0){ /* First time we count the contributions and weights */
                   3814:        gipmx=ipmx;
                   3815:        gsw=sw;
                   3816: }
                   3817: return -l;
1.126     brouard  3818: }
                   3819: 
                   3820: 
                   3821: /*************** function likelione ***********/
                   3822: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3823: {
                   3824:   /* This routine should help understanding what is done with 
                   3825:      the selection of individuals/waves and
                   3826:      to check the exact contribution to the likelihood.
                   3827:      Plotting could be done.
                   3828:    */
                   3829:   int k;
                   3830: 
                   3831:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3832:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3833:     strcat(fileresilk,fileresu);
1.126     brouard  3834:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3835:       printf("Problem with resultfile: %s\n", fileresilk);
                   3836:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3837:     }
1.214     brouard  3838:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3839:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3840:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3841:     for(k=1; k<=nlstate; k++) 
                   3842:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3843:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3844:   }
                   3845: 
                   3846:   *fretone=(*funcone)(p);
                   3847:   if(*globpri !=0){
                   3848:     fclose(ficresilk);
1.205     brouard  3849:     if (mle ==0)
                   3850:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3851:     else if(mle >=1)
                   3852:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3853:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.207     brouard  3854:     
1.208     brouard  3855:       
                   3856:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3857:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3858: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3859:     }
1.207     brouard  3860:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3861: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3862:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3863: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3864:     fflush(fichtm);
1.205     brouard  3865:   }
1.126     brouard  3866:   return;
                   3867: }
                   3868: 
                   3869: 
                   3870: /*********** Maximum Likelihood Estimation ***************/
                   3871: 
                   3872: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3873: {
1.165     brouard  3874:   int i,j, iter=0;
1.126     brouard  3875:   double **xi;
                   3876:   double fret;
                   3877:   double fretone; /* Only one call to likelihood */
                   3878:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3879: 
                   3880: #ifdef NLOPT
                   3881:   int creturn;
                   3882:   nlopt_opt opt;
                   3883:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3884:   double *lb;
                   3885:   double minf; /* the minimum objective value, upon return */
                   3886:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3887:   myfunc_data dinst, *d = &dinst;
                   3888: #endif
                   3889: 
                   3890: 
1.126     brouard  3891:   xi=matrix(1,npar,1,npar);
                   3892:   for (i=1;i<=npar;i++)
                   3893:     for (j=1;j<=npar;j++)
                   3894:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3895:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3896:   strcpy(filerespow,"POW_"); 
1.126     brouard  3897:   strcat(filerespow,fileres);
                   3898:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3899:     printf("Problem with resultfile: %s\n", filerespow);
                   3900:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3901:   }
                   3902:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3903:   for (i=1;i<=nlstate;i++)
                   3904:     for(j=1;j<=nlstate+ndeath;j++)
                   3905:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3906:   fprintf(ficrespow,"\n");
1.162     brouard  3907: #ifdef POWELL
1.126     brouard  3908:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3909: #endif
1.126     brouard  3910: 
1.162     brouard  3911: #ifdef NLOPT
                   3912: #ifdef NEWUOA
                   3913:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3914: #else
                   3915:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3916: #endif
                   3917:   lb=vector(0,npar-1);
                   3918:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3919:   nlopt_set_lower_bounds(opt, lb);
                   3920:   nlopt_set_initial_step1(opt, 0.1);
                   3921:   
                   3922:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3923:   d->function = func;
                   3924:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3925:   nlopt_set_min_objective(opt, myfunc, d);
                   3926:   nlopt_set_xtol_rel(opt, ftol);
                   3927:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3928:     printf("nlopt failed! %d\n",creturn); 
                   3929:   }
                   3930:   else {
                   3931:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3932:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3933:     iter=1; /* not equal */
                   3934:   }
                   3935:   nlopt_destroy(opt);
                   3936: #endif
1.126     brouard  3937:   free_matrix(xi,1,npar,1,npar);
                   3938:   fclose(ficrespow);
1.203     brouard  3939:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3940:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3941:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3942: 
                   3943: }
                   3944: 
                   3945: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3946: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3947: {
                   3948:   double  **a,**y,*x,pd;
1.203     brouard  3949:   /* double **hess; */
1.164     brouard  3950:   int i, j;
1.126     brouard  3951:   int *indx;
                   3952: 
                   3953:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3954:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3955:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   3956:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   3957:   double gompertz(double p[]);
1.203     brouard  3958:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  3959: 
                   3960:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   3961:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   3962:   for (i=1;i<=npar;i++){
1.203     brouard  3963:     printf("%d-",i);fflush(stdout);
                   3964:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  3965:    
                   3966:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   3967:     
                   3968:     /*  printf(" %f ",p[i]);
                   3969:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   3970:   }
                   3971:   
                   3972:   for (i=1;i<=npar;i++) {
                   3973:     for (j=1;j<=npar;j++)  {
                   3974:       if (j>i) { 
1.203     brouard  3975:        printf(".%d-%d",i,j);fflush(stdout);
                   3976:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   3977:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  3978:        
                   3979:        hess[j][i]=hess[i][j];    
                   3980:        /*printf(" %lf ",hess[i][j]);*/
                   3981:       }
                   3982:     }
                   3983:   }
                   3984:   printf("\n");
                   3985:   fprintf(ficlog,"\n");
                   3986: 
                   3987:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3988:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   3989:   
                   3990:   a=matrix(1,npar,1,npar);
                   3991:   y=matrix(1,npar,1,npar);
                   3992:   x=vector(1,npar);
                   3993:   indx=ivector(1,npar);
                   3994:   for (i=1;i<=npar;i++)
                   3995:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   3996:   ludcmp(a,npar,indx,&pd);
                   3997: 
                   3998:   for (j=1;j<=npar;j++) {
                   3999:     for (i=1;i<=npar;i++) x[i]=0;
                   4000:     x[j]=1;
                   4001:     lubksb(a,npar,indx,x);
                   4002:     for (i=1;i<=npar;i++){ 
                   4003:       matcov[i][j]=x[i];
                   4004:     }
                   4005:   }
                   4006: 
                   4007:   printf("\n#Hessian matrix#\n");
                   4008:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4009:   for (i=1;i<=npar;i++) { 
                   4010:     for (j=1;j<=npar;j++) { 
1.203     brouard  4011:       printf("%.6e ",hess[i][j]);
                   4012:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4013:     }
                   4014:     printf("\n");
                   4015:     fprintf(ficlog,"\n");
                   4016:   }
                   4017: 
1.203     brouard  4018:   /* printf("\n#Covariance matrix#\n"); */
                   4019:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4020:   /* for (i=1;i<=npar;i++) {  */
                   4021:   /*   for (j=1;j<=npar;j++) {  */
                   4022:   /*     printf("%.6e ",matcov[i][j]); */
                   4023:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4024:   /*   } */
                   4025:   /*   printf("\n"); */
                   4026:   /*   fprintf(ficlog,"\n"); */
                   4027:   /* } */
                   4028: 
1.126     brouard  4029:   /* Recompute Inverse */
1.203     brouard  4030:   /* for (i=1;i<=npar;i++) */
                   4031:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4032:   /* ludcmp(a,npar,indx,&pd); */
                   4033: 
                   4034:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4035: 
                   4036:   /* for (j=1;j<=npar;j++) { */
                   4037:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4038:   /*   x[j]=1; */
                   4039:   /*   lubksb(a,npar,indx,x); */
                   4040:   /*   for (i=1;i<=npar;i++){  */
                   4041:   /*     y[i][j]=x[i]; */
                   4042:   /*     printf("%.3e ",y[i][j]); */
                   4043:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4044:   /*   } */
                   4045:   /*   printf("\n"); */
                   4046:   /*   fprintf(ficlog,"\n"); */
                   4047:   /* } */
                   4048: 
                   4049:   /* Verifying the inverse matrix */
                   4050: #ifdef DEBUGHESS
                   4051:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4052: 
1.203     brouard  4053:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4054:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4055: 
                   4056:   for (j=1;j<=npar;j++) {
                   4057:     for (i=1;i<=npar;i++){ 
1.203     brouard  4058:       printf("%.2f ",y[i][j]);
                   4059:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4060:     }
                   4061:     printf("\n");
                   4062:     fprintf(ficlog,"\n");
                   4063:   }
1.203     brouard  4064: #endif
1.126     brouard  4065: 
                   4066:   free_matrix(a,1,npar,1,npar);
                   4067:   free_matrix(y,1,npar,1,npar);
                   4068:   free_vector(x,1,npar);
                   4069:   free_ivector(indx,1,npar);
1.203     brouard  4070:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4071: 
                   4072: 
                   4073: }
                   4074: 
                   4075: /*************** hessian matrix ****************/
                   4076: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4077: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4078:   int i;
                   4079:   int l=1, lmax=20;
1.203     brouard  4080:   double k1,k2, res, fx;
1.132     brouard  4081:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4082:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4083:   int k=0,kmax=10;
                   4084:   double l1;
                   4085: 
                   4086:   fx=func(x);
                   4087:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4088:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4089:     l1=pow(10,l);
                   4090:     delts=delt;
                   4091:     for(k=1 ; k <kmax; k=k+1){
                   4092:       delt = delta*(l1*k);
                   4093:       p2[theta]=x[theta] +delt;
1.145     brouard  4094:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4095:       p2[theta]=x[theta]-delt;
                   4096:       k2=func(p2)-fx;
                   4097:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4098:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4099:       
1.203     brouard  4100: #ifdef DEBUGHESSII
1.126     brouard  4101:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4102:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4103: #endif
                   4104:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4105:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4106:        k=kmax;
                   4107:       }
                   4108:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4109:        k=kmax; l=lmax*10;
1.126     brouard  4110:       }
                   4111:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4112:        delts=delt;
                   4113:       }
1.203     brouard  4114:     } /* End loop k */
1.126     brouard  4115:   }
                   4116:   delti[theta]=delts;
                   4117:   return res; 
                   4118:   
                   4119: }
                   4120: 
1.203     brouard  4121: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4122: {
                   4123:   int i;
1.164     brouard  4124:   int l=1, lmax=20;
1.126     brouard  4125:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4126:   double p2[MAXPARM+1];
1.203     brouard  4127:   int k, kmax=1;
                   4128:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4129: 
                   4130:   int firstime=0;
1.203     brouard  4131:   
1.126     brouard  4132:   fx=func(x);
1.203     brouard  4133:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4134:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4135:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4136:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4137:     k1=func(p2)-fx;
                   4138:   
1.203     brouard  4139:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4140:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4141:     k2=func(p2)-fx;
                   4142:   
1.203     brouard  4143:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4144:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4145:     k3=func(p2)-fx;
                   4146:   
1.203     brouard  4147:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4148:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4149:     k4=func(p2)-fx;
1.203     brouard  4150:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4151:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4152:       firstime=1;
1.203     brouard  4153:       kmax=kmax+10;
1.208     brouard  4154:     }
                   4155:     if(kmax >=10 || firstime ==1){
1.246     brouard  4156:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4157:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4158:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4159:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4160:     }
                   4161: #ifdef DEBUGHESSIJ
                   4162:     v1=hess[thetai][thetai];
                   4163:     v2=hess[thetaj][thetaj];
                   4164:     cv12=res;
                   4165:     /* Computing eigen value of Hessian matrix */
                   4166:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4167:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4168:     if ((lc2 <0) || (lc1 <0) ){
                   4169:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4170:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4171:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4172:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4173:     }
1.126     brouard  4174: #endif
                   4175:   }
                   4176:   return res;
                   4177: }
                   4178: 
1.203     brouard  4179:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4180: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4181: /* { */
                   4182: /*   int i; */
                   4183: /*   int l=1, lmax=20; */
                   4184: /*   double k1,k2,k3,k4,res,fx; */
                   4185: /*   double p2[MAXPARM+1]; */
                   4186: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4187: /*   int k=0,kmax=10; */
                   4188: /*   double l1; */
                   4189:   
                   4190: /*   fx=func(x); */
                   4191: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4192: /*     l1=pow(10,l); */
                   4193: /*     delts=delt; */
                   4194: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4195: /*       delt = delti*(l1*k); */
                   4196: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4197: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4198: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4199: /*       k1=func(p2)-fx; */
                   4200:       
                   4201: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4202: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4203: /*       k2=func(p2)-fx; */
                   4204:       
                   4205: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4206: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4207: /*       k3=func(p2)-fx; */
                   4208:       
                   4209: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4210: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4211: /*       k4=func(p2)-fx; */
                   4212: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4213: /* #ifdef DEBUGHESSIJ */
                   4214: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4215: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4216: /* #endif */
                   4217: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4218: /*     k=kmax; */
                   4219: /*       } */
                   4220: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4221: /*     k=kmax; l=lmax*10; */
                   4222: /*       } */
                   4223: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4224: /*     delts=delt; */
                   4225: /*       } */
                   4226: /*     } /\* End loop k *\/ */
                   4227: /*   } */
                   4228: /*   delti[theta]=delts; */
                   4229: /*   return res;  */
                   4230: /* } */
                   4231: 
                   4232: 
1.126     brouard  4233: /************** Inverse of matrix **************/
                   4234: void ludcmp(double **a, int n, int *indx, double *d) 
                   4235: { 
                   4236:   int i,imax,j,k; 
                   4237:   double big,dum,sum,temp; 
                   4238:   double *vv; 
                   4239:  
                   4240:   vv=vector(1,n); 
                   4241:   *d=1.0; 
                   4242:   for (i=1;i<=n;i++) { 
                   4243:     big=0.0; 
                   4244:     for (j=1;j<=n;j++) 
                   4245:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4246:     if (big == 0.0){
                   4247:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4248:       for (j=1;j<=n;j++) {
                   4249:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4250:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4251:       }
                   4252:       fflush(ficlog);
                   4253:       fclose(ficlog);
                   4254:       nrerror("Singular matrix in routine ludcmp"); 
                   4255:     }
1.126     brouard  4256:     vv[i]=1.0/big; 
                   4257:   } 
                   4258:   for (j=1;j<=n;j++) { 
                   4259:     for (i=1;i<j;i++) { 
                   4260:       sum=a[i][j]; 
                   4261:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4262:       a[i][j]=sum; 
                   4263:     } 
                   4264:     big=0.0; 
                   4265:     for (i=j;i<=n;i++) { 
                   4266:       sum=a[i][j]; 
                   4267:       for (k=1;k<j;k++) 
                   4268:        sum -= a[i][k]*a[k][j]; 
                   4269:       a[i][j]=sum; 
                   4270:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4271:        big=dum; 
                   4272:        imax=i; 
                   4273:       } 
                   4274:     } 
                   4275:     if (j != imax) { 
                   4276:       for (k=1;k<=n;k++) { 
                   4277:        dum=a[imax][k]; 
                   4278:        a[imax][k]=a[j][k]; 
                   4279:        a[j][k]=dum; 
                   4280:       } 
                   4281:       *d = -(*d); 
                   4282:       vv[imax]=vv[j]; 
                   4283:     } 
                   4284:     indx[j]=imax; 
                   4285:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4286:     if (j != n) { 
                   4287:       dum=1.0/(a[j][j]); 
                   4288:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4289:     } 
                   4290:   } 
                   4291:   free_vector(vv,1,n);  /* Doesn't work */
                   4292: ;
                   4293: } 
                   4294: 
                   4295: void lubksb(double **a, int n, int *indx, double b[]) 
                   4296: { 
                   4297:   int i,ii=0,ip,j; 
                   4298:   double sum; 
                   4299:  
                   4300:   for (i=1;i<=n;i++) { 
                   4301:     ip=indx[i]; 
                   4302:     sum=b[ip]; 
                   4303:     b[ip]=b[i]; 
                   4304:     if (ii) 
                   4305:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4306:     else if (sum) ii=i; 
                   4307:     b[i]=sum; 
                   4308:   } 
                   4309:   for (i=n;i>=1;i--) { 
                   4310:     sum=b[i]; 
                   4311:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4312:     b[i]=sum/a[i][i]; 
                   4313:   } 
                   4314: } 
                   4315: 
                   4316: void pstamp(FILE *fichier)
                   4317: {
1.196     brouard  4318:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4319: }
                   4320: 
1.253     brouard  4321: 
                   4322: 
1.126     brouard  4323: /************ Frequencies ********************/
1.251     brouard  4324: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4325:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4326:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4327: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4328:   
1.265     brouard  4329:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4330:   int iind=0, iage=0;
                   4331:   int mi; /* Effective wave */
                   4332:   int first;
                   4333:   double ***freq; /* Frequencies */
1.268     brouard  4334:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4335:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.226     brouard  4336:   double *meanq;
                   4337:   double **meanqt;
                   4338:   double *pp, **prop, *posprop, *pospropt;
                   4339:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4340:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4341:   double agebegin, ageend;
                   4342:     
                   4343:   pp=vector(1,nlstate);
1.251     brouard  4344:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4345:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4346:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4347:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4348:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
                   4349:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4350:   strcpy(fileresp,"P_");
                   4351:   strcat(fileresp,fileresu);
                   4352:   /*strcat(fileresphtm,fileresu);*/
                   4353:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4354:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4355:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4356:     exit(0);
                   4357:   }
1.240     brouard  4358:   
1.226     brouard  4359:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4360:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4361:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4362:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4363:     fflush(ficlog);
                   4364:     exit(70); 
                   4365:   }
                   4366:   else{
                   4367:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4368: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4369: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4370:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4371:   }
1.237     brouard  4372:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4373:   
1.226     brouard  4374:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4375:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4376:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4377:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4378:     fflush(ficlog);
                   4379:     exit(70); 
1.240     brouard  4380:   } else{
1.226     brouard  4381:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4382: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4383: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4384:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4385:   }
1.240     brouard  4386:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4387:   
1.253     brouard  4388:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4389:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4390:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4391:   j1=0;
1.126     brouard  4392:   
1.227     brouard  4393:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4394:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4395:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4396:   
                   4397:   
1.226     brouard  4398:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4399:      reference=low_education V1=0,V2=0
                   4400:      med_educ                V1=1 V2=0, 
                   4401:      high_educ               V1=0 V2=1
                   4402:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4403:   */
1.249     brouard  4404:   dateintsum=0;
                   4405:   k2cpt=0;
                   4406: 
1.253     brouard  4407:   if(cptcoveff == 0 )
1.265     brouard  4408:     nl=1;  /* Constant and age model only */
1.253     brouard  4409:   else
                   4410:     nl=2;
1.265     brouard  4411: 
                   4412:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4413:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4414:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4415:    *     freq[s1][s2][iage] =0.
                   4416:    *     Loop on iind
                   4417:    *       ++freq[s1][s2][iage] weighted
                   4418:    *     end iind
                   4419:    *     if covariate and j!0
                   4420:    *       headers Variable on one line
                   4421:    *     endif cov j!=0
                   4422:    *     header of frequency table by age
                   4423:    *     Loop on age
                   4424:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4425:    *       pos+=freq[s1][s2][iage] weighted
                   4426:    *       Loop on s1 initial state
                   4427:    *         fprintf(ficresp
                   4428:    *       end s1
                   4429:    *     end age
                   4430:    *     if j!=0 computes starting values
                   4431:    *     end compute starting values
                   4432:    *   end j1
                   4433:    * end nl 
                   4434:    */
1.253     brouard  4435:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4436:     if(nj==1)
                   4437:       j=0;  /* First pass for the constant */
1.265     brouard  4438:     else{
1.253     brouard  4439:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4440:     }
1.251     brouard  4441:     first=1;
1.265     brouard  4442:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4443:       posproptt=0.;
                   4444:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4445:        scanf("%d", i);*/
                   4446:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4447:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4448:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4449:            freq[i][s2][m]=0;
1.251     brouard  4450:       
                   4451:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4452:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4453:          prop[i][m]=0;
                   4454:        posprop[i]=0;
                   4455:        pospropt[i]=0;
                   4456:       }
                   4457:       /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4458:       /*   meanq[z1]+=0.; */
                   4459:       /*   for(m=1;m<=lastpass;m++){ */
                   4460:       /*       meanqt[m][z1]=0.; */
                   4461:       /*   } */
                   4462:       /* } */
                   4463:       
                   4464:       /* dateintsum=0; */
                   4465:       /* k2cpt=0; */
                   4466:       
1.265     brouard  4467:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4468:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4469:        bool=1;
                   4470:        if(j !=0){
                   4471:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4472:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4473:              /* for (z1=1; z1<= nqfveff; z1++) {   */
                   4474:              /*   meanq[z1]+=coqvar[Tvar[z1]][iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4475:              /* } */
                   4476:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4477:                /* if(Tvaraff[z1] ==-20){ */
                   4478:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4479:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4480:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4481:                /* }else  */
                   4482:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4483:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4484:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4485:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4486:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4487:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4488:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4489:                } /* Onlyf fixed */
                   4490:              } /* end z1 */
                   4491:            } /* cptcovn > 0 */
                   4492:          } /* end any */
                   4493:        }/* end j==0 */
1.265     brouard  4494:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4495:          /* for(m=firstpass; m<=lastpass; m++){ */
                   4496:          for(mi=1; mi<wav[iind];mi++){ /* For that wave */
                   4497:            m=mw[mi][iind];
                   4498:            if(j!=0){
                   4499:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4500:                for (z1=1; z1<=cptcoveff; z1++) {
                   4501:                  if( Fixed[Tmodelind[z1]]==1){
                   4502:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4503:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4504:                                                                                      value is -1, we don't select. It differs from the 
                   4505:                                                                                      constant and age model which counts them. */
                   4506:                      bool=0; /* not selected */
                   4507:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4508:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4509:                      bool=0;
                   4510:                    }
                   4511:                  }
                   4512:                }
                   4513:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4514:            } /* end j==0 */
                   4515:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
                   4516:            if(bool==1){
                   4517:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4518:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4519:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4520:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4521:              if(m >=firstpass && m <=lastpass){
                   4522:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4523:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4524:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4525:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4526:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4527:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4528:                if (m<lastpass) {
                   4529:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4530:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4531:                  if(s[m][iind]==-1)
                   4532:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4533:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
                   4534:                  /* if((int)agev[m][iind] == 55) */
                   4535:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4536:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4537:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4538:                }
1.251     brouard  4539:              } /* end if between passes */  
                   4540:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4541:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4542:                k2cpt++;
                   4543:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4544:              }
1.251     brouard  4545:            }else{
                   4546:              bool=1;
                   4547:            }/* end bool 2 */
                   4548:          } /* end m */
                   4549:        } /* end bool */
                   4550:       } /* end iind = 1 to imx */
                   4551:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4552:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4553:       
                   4554:       
                   4555:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4556:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4557:         pstamp(ficresp);
1.251     brouard  4558:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4559:         pstamp(ficresp);
1.251     brouard  4560:        printf( "\n#********** Variable "); 
                   4561:        fprintf(ficresp, "\n#********** Variable "); 
                   4562:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4563:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4564:        fprintf(ficlog, "\n#********** Variable "); 
                   4565:        for (z1=1; z1<=cptcoveff; z1++){
                   4566:          if(!FixedV[Tvaraff[z1]]){
                   4567:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4568:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4569:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4570:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4571:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4572:          }else{
1.251     brouard  4573:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4574:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4575:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4576:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4577:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4578:          }
                   4579:        }
                   4580:        printf( "**********\n#");
                   4581:        fprintf(ficresp, "**********\n#");
                   4582:        fprintf(ficresphtm, "**********</h3>\n");
                   4583:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4584:        fprintf(ficlog, "**********\n");
                   4585:       }
                   4586:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4587:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4588:         fprintf(ficresp, " Age");
                   4589:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4590:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4591:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4592:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4593:       }
1.265     brouard  4594:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4595:       fprintf(ficresphtm, "\n");
                   4596:       
                   4597:       /* Header of frequency table by age */
                   4598:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4599:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4600:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4601:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4602:          if(s2!=0 && m!=0)
                   4603:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4604:        }
1.226     brouard  4605:       }
1.251     brouard  4606:       fprintf(ficresphtmfr, "\n");
                   4607:     
                   4608:       /* For each age */
                   4609:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4610:        fprintf(ficresphtm,"<tr>");
                   4611:        if(iage==iagemax+1){
                   4612:          fprintf(ficlog,"1");
                   4613:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4614:        }else if(iage==iagemax+2){
                   4615:          fprintf(ficlog,"0");
                   4616:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4617:        }else if(iage==iagemax+3){
                   4618:          fprintf(ficlog,"Total");
                   4619:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4620:        }else{
1.240     brouard  4621:          if(first==1){
1.251     brouard  4622:            first=0;
                   4623:            printf("See log file for details...\n");
                   4624:          }
                   4625:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4626:          fprintf(ficlog,"Age %d", iage);
                   4627:        }
1.265     brouard  4628:        for(s1=1; s1 <=nlstate ; s1++){
                   4629:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4630:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4631:        }
1.265     brouard  4632:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4633:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4634:            pos += freq[s1][m][iage];
                   4635:          if(pp[s1]>=1.e-10){
1.251     brouard  4636:            if(first==1){
1.265     brouard  4637:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4638:            }
1.265     brouard  4639:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4640:          }else{
                   4641:            if(first==1)
1.265     brouard  4642:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4643:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4644:          }
                   4645:        }
                   4646:       
1.265     brouard  4647:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4648:          /* posprop[s1]=0; */
                   4649:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4650:            pp[s1] += freq[s1][m][iage];
                   4651:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4652:       
                   4653:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4654:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4655:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4656:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4657:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4658:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4659:        }
                   4660:        
                   4661:        /* Writing ficresp */
                   4662:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4663:           if( iage <= iagemax){
                   4664:            fprintf(ficresp," %d",iage);
                   4665:           }
                   4666:         }else if( nj==2){
                   4667:           if( iage <= iagemax){
                   4668:            fprintf(ficresp," %d",iage);
                   4669:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4670:           }
1.240     brouard  4671:        }
1.265     brouard  4672:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4673:          if(pos>=1.e-5){
1.251     brouard  4674:            if(first==1)
1.265     brouard  4675:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4676:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4677:          }else{
                   4678:            if(first==1)
1.265     brouard  4679:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4680:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4681:          }
                   4682:          if( iage <= iagemax){
                   4683:            if(pos>=1.e-5){
1.265     brouard  4684:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4685:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4686:               }else if( nj==2){
                   4687:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4688:               }
                   4689:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4690:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4691:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4692:            } else{
                   4693:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4694:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4695:            }
1.240     brouard  4696:          }
1.265     brouard  4697:          pospropt[s1] +=posprop[s1];
                   4698:        } /* end loop s1 */
1.251     brouard  4699:        /* pospropt=0.; */
1.265     brouard  4700:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4701:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4702:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4703:              if(first==1){
1.265     brouard  4704:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4705:              }
1.265     brouard  4706:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4707:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4708:            }
1.265     brouard  4709:            if(s1!=0 && m!=0)
                   4710:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4711:          }
1.265     brouard  4712:        } /* end loop s1 */
1.251     brouard  4713:        posproptt=0.; 
1.265     brouard  4714:        for(s1=1; s1 <=nlstate; s1++){
                   4715:          posproptt += pospropt[s1];
1.251     brouard  4716:        }
                   4717:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4718:        fprintf(ficresphtm,"</tr>\n");
                   4719:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4720:          if(iage <= iagemax)
                   4721:            fprintf(ficresp,"\n");
1.240     brouard  4722:        }
1.251     brouard  4723:        if(first==1)
                   4724:          printf("Others in log...\n");
                   4725:        fprintf(ficlog,"\n");
                   4726:       } /* end loop age iage */
1.265     brouard  4727:       
1.251     brouard  4728:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4729:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4730:        if(posproptt < 1.e-5){
1.265     brouard  4731:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4732:        }else{
1.265     brouard  4733:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4734:        }
1.226     brouard  4735:       }
1.251     brouard  4736:       fprintf(ficresphtm,"</tr>\n");
                   4737:       fprintf(ficresphtm,"</table>\n");
                   4738:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4739:       if(posproptt < 1.e-5){
1.251     brouard  4740:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4741:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4742:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4743:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4744:        invalidvarcomb[j1]=1;
1.226     brouard  4745:       }else{
1.251     brouard  4746:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4747:        invalidvarcomb[j1]=0;
1.226     brouard  4748:       }
1.251     brouard  4749:       fprintf(ficresphtmfr,"</table>\n");
                   4750:       fprintf(ficlog,"\n");
                   4751:       if(j!=0){
                   4752:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4753:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4754:          for(k=1; k <=(nlstate+ndeath); k++){
                   4755:            if (k != i) {
1.265     brouard  4756:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4757:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4758:                  if(j1==1){ /* All dummy covariates to zero */
                   4759:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4760:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4761:                    printf("%d%d ",i,k);
                   4762:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4763:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4764:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4765:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4766:                  }
1.253     brouard  4767:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4768:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4769:                    x[iage]= (double)iage;
                   4770:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4771:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4772:                  }
1.268     brouard  4773:                  /* Some are not finite, but linreg will ignore these ages */
                   4774:                  no=0;
1.253     brouard  4775:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4776:                  pstart[s1]=b;
                   4777:                  pstart[s1-1]=a;
1.252     brouard  4778:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4779:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4780:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4781:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4782:                  printf("%d%d ",i,k);
                   4783:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4784:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4785:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4786:                  ;
                   4787:                }
                   4788:                /* printf("%12.7f )", param[i][jj][k]); */
                   4789:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4790:                s1++; 
1.251     brouard  4791:              } /* end jj */
                   4792:            } /* end k!= i */
                   4793:          } /* end k */
1.265     brouard  4794:        } /* end i, s1 */
1.251     brouard  4795:       } /* end j !=0 */
                   4796:     } /* end selected combination of covariate j1 */
                   4797:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4798:       printf("#Freqsummary: Starting values for the constants:\n");
                   4799:       fprintf(ficlog,"\n");
1.265     brouard  4800:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4801:        for(k=1; k <=(nlstate+ndeath); k++){
                   4802:          if (k != i) {
                   4803:            printf("%d%d ",i,k);
                   4804:            fprintf(ficlog,"%d%d ",i,k);
                   4805:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4806:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4807:              if(jj==1){ /* Age has to be done */
1.265     brouard  4808:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4809:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4810:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4811:              }
                   4812:              /* printf("%12.7f )", param[i][jj][k]); */
                   4813:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4814:              s1++; 
1.250     brouard  4815:            }
1.251     brouard  4816:            printf("\n");
                   4817:            fprintf(ficlog,"\n");
1.250     brouard  4818:          }
                   4819:        }
                   4820:       }
1.251     brouard  4821:       printf("#Freqsummary\n");
                   4822:       fprintf(ficlog,"\n");
1.265     brouard  4823:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4824:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4825:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4826:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4827:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4828:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4829:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4830:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4831:          /* } */
                   4832:        }
1.265     brouard  4833:       } /* end loop s1 */
1.251     brouard  4834:       
                   4835:       printf("\n");
                   4836:       fprintf(ficlog,"\n");
                   4837:     } /* end j=0 */
1.249     brouard  4838:   } /* end j */
1.252     brouard  4839: 
1.253     brouard  4840:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4841:     for(i=1, jk=1; i <=nlstate; i++){
                   4842:       for(j=1; j <=nlstate+ndeath; j++){
                   4843:        if(j!=i){
                   4844:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4845:          printf("%1d%1d",i,j);
                   4846:          fprintf(ficparo,"%1d%1d",i,j);
                   4847:          for(k=1; k<=ncovmodel;k++){
                   4848:            /*    printf(" %lf",param[i][j][k]); */
                   4849:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4850:            p[jk]=pstart[jk];
                   4851:            printf(" %f ",pstart[jk]);
                   4852:            fprintf(ficparo," %f ",pstart[jk]);
                   4853:            jk++;
                   4854:          }
                   4855:          printf("\n");
                   4856:          fprintf(ficparo,"\n");
                   4857:        }
                   4858:       }
                   4859:     }
                   4860:   } /* end mle=-2 */
1.226     brouard  4861:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4862:   
1.226     brouard  4863:   fclose(ficresp);
                   4864:   fclose(ficresphtm);
                   4865:   fclose(ficresphtmfr);
                   4866:   free_vector(meanq,1,nqfveff);
                   4867:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4868:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4869:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4870:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4871:   free_vector(pospropt,1,nlstate);
                   4872:   free_vector(posprop,1,nlstate);
1.251     brouard  4873:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4874:   free_vector(pp,1,nlstate);
                   4875:   /* End of freqsummary */
                   4876: }
1.126     brouard  4877: 
1.268     brouard  4878: /* Simple linear regression */
                   4879: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4880: 
                   4881:   /* y=a+bx regression */
                   4882:   double   sumx = 0.0;                        /* sum of x                      */
                   4883:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4884:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4885:   double   sumy = 0.0;                        /* sum of y                      */
                   4886:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4887:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4888:   double yhat;
                   4889:   
                   4890:   double denom=0;
                   4891:   int i;
                   4892:   int ne=*no;
                   4893:   
                   4894:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4895:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4896:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4897:       continue;
                   4898:     }
                   4899:     ne=ne+1;
                   4900:     sumx  += x[i];       
                   4901:     sumx2 += x[i]*x[i];  
                   4902:     sumxy += x[i] * y[i];
                   4903:     sumy  += y[i];      
                   4904:     sumy2 += y[i]*y[i]; 
                   4905:     denom = (ne * sumx2 - sumx*sumx);
                   4906:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4907:   } 
                   4908:   
                   4909:   denom = (ne * sumx2 - sumx*sumx);
                   4910:   if (denom == 0) {
                   4911:     // vertical, slope m is infinity
                   4912:     *b = INFINITY;
                   4913:     *a = 0;
                   4914:     if (r) *r = 0;
                   4915:     return 1;
                   4916:   }
                   4917:   
                   4918:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4919:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4920:   if (r!=NULL) {
                   4921:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   4922:       sqrt((sumx2 - sumx*sumx/ne) *
                   4923:           (sumy2 - sumy*sumy/ne));
                   4924:   }
                   4925:   *no=ne;
                   4926:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4927:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4928:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4929:       continue;
                   4930:     }
                   4931:     ne=ne+1;
                   4932:     yhat = y[i] - *a -*b* x[i];
                   4933:     sume2  += yhat * yhat ;       
                   4934:     
                   4935:     denom = (ne * sumx2 - sumx*sumx);
                   4936:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4937:   } 
                   4938:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   4939:   *sa= *sb * sqrt(sumx2/ne);
                   4940:   
                   4941:   return 0; 
                   4942: }
                   4943: 
1.126     brouard  4944: /************ Prevalence ********************/
1.227     brouard  4945: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   4946: {  
                   4947:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   4948:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   4949:      We still use firstpass and lastpass as another selection.
                   4950:   */
1.126     brouard  4951:  
1.227     brouard  4952:   int i, m, jk, j1, bool, z1,j, iv;
                   4953:   int mi; /* Effective wave */
                   4954:   int iage;
                   4955:   double agebegin, ageend;
                   4956: 
                   4957:   double **prop;
                   4958:   double posprop; 
                   4959:   double  y2; /* in fractional years */
                   4960:   int iagemin, iagemax;
                   4961:   int first; /** to stop verbosity which is redirected to log file */
                   4962: 
                   4963:   iagemin= (int) agemin;
                   4964:   iagemax= (int) agemax;
                   4965:   /*pp=vector(1,nlstate);*/
1.251     brouard  4966:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  4967:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   4968:   j1=0;
1.222     brouard  4969:   
1.227     brouard  4970:   /*j=cptcoveff;*/
                   4971:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  4972:   
1.227     brouard  4973:   first=1;
                   4974:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   4975:     for (i=1; i<=nlstate; i++)  
1.251     brouard  4976:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  4977:        prop[i][iage]=0.0;
                   4978:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   4979:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   4980:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   4981:     
                   4982:     for (i=1; i<=imx; i++) { /* Each individual */
                   4983:       bool=1;
                   4984:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   4985:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   4986:        m=mw[mi][i];
                   4987:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   4988:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   4989:        for (z1=1; z1<=cptcoveff; z1++){
                   4990:          if( Fixed[Tmodelind[z1]]==1){
                   4991:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4992:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   4993:              bool=0;
                   4994:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   4995:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4996:              bool=0;
                   4997:            }
                   4998:        }
                   4999:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5000:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5001:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5002:          if(m >=firstpass && m <=lastpass){
                   5003:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5004:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5005:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5006:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5007:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5008:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5009:                exit(1);
                   5010:              }
                   5011:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5012:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5013:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5014:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5015:              } /* end valid statuses */ 
                   5016:            } /* end selection of dates */
                   5017:          } /* end selection of waves */
                   5018:        } /* end bool */
                   5019:       } /* end wave */
                   5020:     } /* end individual */
                   5021:     for(i=iagemin; i <= iagemax+3; i++){  
                   5022:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5023:        posprop += prop[jk][i]; 
                   5024:       } 
                   5025:       
                   5026:       for(jk=1; jk <=nlstate ; jk++){      
                   5027:        if( i <=  iagemax){ 
                   5028:          if(posprop>=1.e-5){ 
                   5029:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5030:          } else{
                   5031:            if(first==1){
                   5032:              first=0;
1.266     brouard  5033:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5034:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5035:            }else{
                   5036:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5037:            }
                   5038:          }
                   5039:        } 
                   5040:       }/* end jk */ 
                   5041:     }/* end i */ 
1.222     brouard  5042:      /*} *//* end i1 */
1.227     brouard  5043:   } /* end j1 */
1.222     brouard  5044:   
1.227     brouard  5045:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5046:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5047:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5048: }  /* End of prevalence */
1.126     brouard  5049: 
                   5050: /************* Waves Concatenation ***************/
                   5051: 
                   5052: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5053: {
                   5054:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5055:      Death is a valid wave (if date is known).
                   5056:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5057:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5058:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5059:   */
1.126     brouard  5060: 
1.224     brouard  5061:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5062:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5063:      double sum=0., jmean=0.;*/
1.224     brouard  5064:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5065:   int j, k=0,jk, ju, jl;
                   5066:   double sum=0.;
                   5067:   first=0;
1.214     brouard  5068:   firstwo=0;
1.217     brouard  5069:   firsthree=0;
1.218     brouard  5070:   firstfour=0;
1.164     brouard  5071:   jmin=100000;
1.126     brouard  5072:   jmax=-1;
                   5073:   jmean=0.;
1.224     brouard  5074: 
                   5075: /* Treating live states */
1.214     brouard  5076:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5077:     mi=0;  /* First valid wave */
1.227     brouard  5078:     mli=0; /* Last valid wave */
1.126     brouard  5079:     m=firstpass;
1.214     brouard  5080:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5081:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5082:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5083:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5084:        mw[++mi][i]=m;
                   5085:        mli=m;
1.224     brouard  5086:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5087:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5088:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5089:       }
1.227     brouard  5090:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5091: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5092:        break;
1.224     brouard  5093: #else
1.227     brouard  5094:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5095:          if(firsthree == 0){
1.262     brouard  5096:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5097:            firsthree=1;
                   5098:          }
1.262     brouard  5099:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5100:          mw[++mi][i]=m;
                   5101:          mli=m;
                   5102:        }
                   5103:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5104:          nbwarn++;
                   5105:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5106:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5107:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5108:          }
                   5109:          break;
                   5110:        }
                   5111:        break;
1.224     brouard  5112: #endif
1.227     brouard  5113:       }/* End m >= lastpass */
1.126     brouard  5114:     }/* end while */
1.224     brouard  5115: 
1.227     brouard  5116:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5117:     /* After last pass */
1.224     brouard  5118: /* Treating death states */
1.214     brouard  5119:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5120:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5121:       /* } */
1.126     brouard  5122:       mi++;    /* Death is another wave */
                   5123:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5124:       /* Only death is a correct wave */
1.126     brouard  5125:       mw[mi][i]=m;
1.257     brouard  5126:     } /* else not in a death state */
1.224     brouard  5127: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5128:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5129:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5130:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5131:          nbwarn++;
                   5132:          if(firstfiv==0){
                   5133:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5134:            firstfiv=1;
                   5135:          }else{
                   5136:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5137:          }
                   5138:        }else{ /* Death occured afer last wave potential bias */
                   5139:          nberr++;
                   5140:          if(firstwo==0){
1.257     brouard  5141:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5142:            firstwo=1;
                   5143:          }
1.257     brouard  5144:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5145:        }
1.257     brouard  5146:       }else{ /* if date of interview is unknown */
1.227     brouard  5147:        /* death is known but not confirmed by death status at any wave */
                   5148:        if(firstfour==0){
                   5149:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5150:          firstfour=1;
                   5151:        }
                   5152:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5153:       }
1.224     brouard  5154:     } /* end if date of death is known */
                   5155: #endif
                   5156:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5157:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5158:     if(mi==0){
                   5159:       nbwarn++;
                   5160:       if(first==0){
1.227     brouard  5161:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5162:        first=1;
1.126     brouard  5163:       }
                   5164:       if(first==1){
1.227     brouard  5165:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5166:       }
                   5167:     } /* end mi==0 */
                   5168:   } /* End individuals */
1.214     brouard  5169:   /* wav and mw are no more changed */
1.223     brouard  5170:        
1.214     brouard  5171:   
1.126     brouard  5172:   for(i=1; i<=imx; i++){
                   5173:     for(mi=1; mi<wav[i];mi++){
                   5174:       if (stepm <=0)
1.227     brouard  5175:        dh[mi][i]=1;
1.126     brouard  5176:       else{
1.260     brouard  5177:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5178:          if (agedc[i] < 2*AGESUP) {
                   5179:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5180:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5181:            else if(j<0){
                   5182:              nberr++;
                   5183:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5184:              j=1; /* Temporary Dangerous patch */
                   5185:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5186:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5187:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5188:            }
                   5189:            k=k+1;
                   5190:            if (j >= jmax){
                   5191:              jmax=j;
                   5192:              ijmax=i;
                   5193:            }
                   5194:            if (j <= jmin){
                   5195:              jmin=j;
                   5196:              ijmin=i;
                   5197:            }
                   5198:            sum=sum+j;
                   5199:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5200:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5201:          }
                   5202:        }
                   5203:        else{
                   5204:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5205: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5206:                                        
1.227     brouard  5207:          k=k+1;
                   5208:          if (j >= jmax) {
                   5209:            jmax=j;
                   5210:            ijmax=i;
                   5211:          }
                   5212:          else if (j <= jmin){
                   5213:            jmin=j;
                   5214:            ijmin=i;
                   5215:          }
                   5216:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5217:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5218:          if(j<0){
                   5219:            nberr++;
                   5220:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5221:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5222:          }
                   5223:          sum=sum+j;
                   5224:        }
                   5225:        jk= j/stepm;
                   5226:        jl= j -jk*stepm;
                   5227:        ju= j -(jk+1)*stepm;
                   5228:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5229:          if(jl==0){
                   5230:            dh[mi][i]=jk;
                   5231:            bh[mi][i]=0;
                   5232:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5233:                  * to avoid the price of an extra matrix product in likelihood */
                   5234:            dh[mi][i]=jk+1;
                   5235:            bh[mi][i]=ju;
                   5236:          }
                   5237:        }else{
                   5238:          if(jl <= -ju){
                   5239:            dh[mi][i]=jk;
                   5240:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5241:                                 * is higher than the multiple of stepm and negative otherwise.
                   5242:                                 */
                   5243:          }
                   5244:          else{
                   5245:            dh[mi][i]=jk+1;
                   5246:            bh[mi][i]=ju;
                   5247:          }
                   5248:          if(dh[mi][i]==0){
                   5249:            dh[mi][i]=1; /* At least one step */
                   5250:            bh[mi][i]=ju; /* At least one step */
                   5251:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5252:          }
                   5253:        } /* end if mle */
1.126     brouard  5254:       }
                   5255:     } /* end wave */
                   5256:   }
                   5257:   jmean=sum/k;
                   5258:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5259:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5260: }
1.126     brouard  5261: 
                   5262: /*********** Tricode ****************************/
1.220     brouard  5263:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5264:  {
                   5265:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5266:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5267:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5268:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5269:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5270:     */
1.130     brouard  5271: 
1.242     brouard  5272:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5273:    int modmaxcovj=0; /* Modality max of covariates j */
                   5274:    int cptcode=0; /* Modality max of covariates j */
                   5275:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5276: 
                   5277: 
1.242     brouard  5278:    /* cptcoveff=0;  */
                   5279:    /* *cptcov=0; */
1.126     brouard  5280:  
1.242     brouard  5281:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.126     brouard  5282: 
1.242     brouard  5283:    /* Loop on covariates without age and products and no quantitative variable */
                   5284:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5285:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5286:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5287:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5288:        switch(Fixed[k]) {
                   5289:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5290:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5291:           ij=(int)(covar[Tvar[k]][i]);
                   5292:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5293:            * If product of Vn*Vm, still boolean *:
                   5294:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5295:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5296:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5297:              modality of the nth covariate of individual i. */
                   5298:           if (ij > modmaxcovj)
                   5299:             modmaxcovj=ij; 
                   5300:           else if (ij < modmincovj) 
                   5301:             modmincovj=ij; 
                   5302:           if ((ij < -1) && (ij > NCOVMAX)){
                   5303:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5304:             exit(1);
                   5305:           }else
                   5306:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5307:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5308:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5309:           /* getting the maximum value of the modality of the covariate
                   5310:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5311:              female ies 1, then modmaxcovj=1.
                   5312:           */
                   5313:         } /* end for loop on individuals i */
                   5314:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5315:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5316:         cptcode=modmaxcovj;
                   5317:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5318:         /*for (i=0; i<=cptcode; i++) {*/
                   5319:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5320:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5321:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5322:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5323:             if( j != -1){
                   5324:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5325:                                  covariate for which somebody answered excluding 
                   5326:                                  undefined. Usually 2: 0 and 1. */
                   5327:             }
                   5328:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5329:                                     covariate for which somebody answered including 
                   5330:                                     undefined. Usually 3: -1, 0 and 1. */
                   5331:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5332:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5333:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5334:                        
1.242     brouard  5335:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5336:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5337:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5338:         /* modmincovj=3; modmaxcovj = 7; */
                   5339:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5340:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5341:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5342:         /* nbcode[Tvar[j]][ij]=k; */
                   5343:         /* nbcode[Tvar[j]][1]=0; */
                   5344:         /* nbcode[Tvar[j]][2]=1; */
                   5345:         /* nbcode[Tvar[j]][3]=2; */
                   5346:         /* To be continued (not working yet). */
                   5347:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5348:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5349:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5350:             break;
                   5351:           }
                   5352:           ij++;
                   5353:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5354:           cptcode = ij; /* New max modality for covar j */
                   5355:         } /* end of loop on modality i=-1 to 1 or more */
                   5356:         break;
                   5357:        case 1: /* Testing on varying covariate, could be simple and
                   5358:                * should look at waves or product of fixed *
                   5359:                * varying. No time to test -1, assuming 0 and 1 only */
                   5360:         ij=0;
                   5361:         for(i=0; i<=1;i++){
                   5362:           nbcode[Tvar[k]][++ij]=i;
                   5363:         }
                   5364:         break;
                   5365:        default:
                   5366:         break;
                   5367:        } /* end switch */
                   5368:      } /* end dummy test */
                   5369:     
                   5370:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5371:      /*        /\*recode from 0 *\/ */
                   5372:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5373:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5374:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5375:      /*        } */
                   5376:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5377:      /*        if (ij > ncodemax[j]) { */
                   5378:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5379:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5380:      /*          break; */
                   5381:      /*        } */
                   5382:      /*   }  /\* end of loop on modality k *\/ */
                   5383:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5384:   
                   5385:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5386:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5387:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5388:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5389:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5390:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5391:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5392:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5393:   
                   5394:    ij=0;
                   5395:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5396:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5397:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5398:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5399:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5400:        /* If product not in single variable we don't print results */
                   5401:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5402:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5403:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5404:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5405:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5406:        if(Fixed[k]!=0)
                   5407:         anyvaryingduminmodel=1;
                   5408:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5409:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5410:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5411:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5412:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5413:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5414:      } 
                   5415:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5416:    /* ij--; */
                   5417:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5418:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5419:                * because they can be excluded from the model and real
                   5420:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5421:    for(j=ij+1; j<= cptcovt; j++){
                   5422:      Tvaraff[j]=0;
                   5423:      Tmodelind[j]=0;
                   5424:    }
                   5425:    for(j=ntveff+1; j<= cptcovt; j++){
                   5426:      TmodelInvind[j]=0;
                   5427:    }
                   5428:    /* To be sorted */
                   5429:    ;
                   5430:  }
1.126     brouard  5431: 
1.145     brouard  5432: 
1.126     brouard  5433: /*********** Health Expectancies ****************/
                   5434: 
1.235     brouard  5435:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5436: 
                   5437: {
                   5438:   /* Health expectancies, no variances */
1.164     brouard  5439:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5440:   int nhstepma, nstepma; /* Decreasing with age */
                   5441:   double age, agelim, hf;
                   5442:   double ***p3mat;
                   5443:   double eip;
                   5444: 
1.238     brouard  5445:   /* pstamp(ficreseij); */
1.126     brouard  5446:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5447:   fprintf(ficreseij,"# Age");
                   5448:   for(i=1; i<=nlstate;i++){
                   5449:     for(j=1; j<=nlstate;j++){
                   5450:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5451:     }
                   5452:     fprintf(ficreseij," e%1d. ",i);
                   5453:   }
                   5454:   fprintf(ficreseij,"\n");
                   5455: 
                   5456:   
                   5457:   if(estepm < stepm){
                   5458:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5459:   }
                   5460:   else  hstepm=estepm;   
                   5461:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5462:    * This is mainly to measure the difference between two models: for example
                   5463:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5464:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5465:    * progression in between and thus overestimating or underestimating according
                   5466:    * to the curvature of the survival function. If, for the same date, we 
                   5467:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5468:    * to compare the new estimate of Life expectancy with the same linear 
                   5469:    * hypothesis. A more precise result, taking into account a more precise
                   5470:    * curvature will be obtained if estepm is as small as stepm. */
                   5471: 
                   5472:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5473:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5474:      nhstepm is the number of hstepm from age to agelim 
                   5475:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5476:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5477:      and note for a fixed period like estepm months */
                   5478:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5479:      survival function given by stepm (the optimization length). Unfortunately it
                   5480:      means that if the survival funtion is printed only each two years of age and if
                   5481:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5482:      results. So we changed our mind and took the option of the best precision.
                   5483:   */
                   5484:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5485: 
                   5486:   agelim=AGESUP;
                   5487:   /* If stepm=6 months */
                   5488:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5489:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5490:     
                   5491: /* nhstepm age range expressed in number of stepm */
                   5492:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5493:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5494:   /* if (stepm >= YEARM) hstepm=1;*/
                   5495:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5496:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5497: 
                   5498:   for (age=bage; age<=fage; age ++){ 
                   5499:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5500:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5501:     /* if (stepm >= YEARM) hstepm=1;*/
                   5502:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5503: 
                   5504:     /* If stepm=6 months */
                   5505:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5506:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5507:     
1.235     brouard  5508:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5509:     
                   5510:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5511:     
                   5512:     printf("%d|",(int)age);fflush(stdout);
                   5513:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5514:     
                   5515:     /* Computing expectancies */
                   5516:     for(i=1; i<=nlstate;i++)
                   5517:       for(j=1; j<=nlstate;j++)
                   5518:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5519:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5520:          
                   5521:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5522: 
                   5523:        }
                   5524: 
                   5525:     fprintf(ficreseij,"%3.0f",age );
                   5526:     for(i=1; i<=nlstate;i++){
                   5527:       eip=0;
                   5528:       for(j=1; j<=nlstate;j++){
                   5529:        eip +=eij[i][j][(int)age];
                   5530:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5531:       }
                   5532:       fprintf(ficreseij,"%9.4f", eip );
                   5533:     }
                   5534:     fprintf(ficreseij,"\n");
                   5535:     
                   5536:   }
                   5537:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5538:   printf("\n");
                   5539:   fprintf(ficlog,"\n");
                   5540:   
                   5541: }
                   5542: 
1.235     brouard  5543:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5544: 
                   5545: {
                   5546:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5547:      to initial status i, ei. .
1.126     brouard  5548:   */
                   5549:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5550:   int nhstepma, nstepma; /* Decreasing with age */
                   5551:   double age, agelim, hf;
                   5552:   double ***p3matp, ***p3matm, ***varhe;
                   5553:   double **dnewm,**doldm;
                   5554:   double *xp, *xm;
                   5555:   double **gp, **gm;
                   5556:   double ***gradg, ***trgradg;
                   5557:   int theta;
                   5558: 
                   5559:   double eip, vip;
                   5560: 
                   5561:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5562:   xp=vector(1,npar);
                   5563:   xm=vector(1,npar);
                   5564:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5565:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5566:   
                   5567:   pstamp(ficresstdeij);
                   5568:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5569:   fprintf(ficresstdeij,"# Age");
                   5570:   for(i=1; i<=nlstate;i++){
                   5571:     for(j=1; j<=nlstate;j++)
                   5572:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5573:     fprintf(ficresstdeij," e%1d. ",i);
                   5574:   }
                   5575:   fprintf(ficresstdeij,"\n");
                   5576: 
                   5577:   pstamp(ficrescveij);
                   5578:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5579:   fprintf(ficrescveij,"# Age");
                   5580:   for(i=1; i<=nlstate;i++)
                   5581:     for(j=1; j<=nlstate;j++){
                   5582:       cptj= (j-1)*nlstate+i;
                   5583:       for(i2=1; i2<=nlstate;i2++)
                   5584:        for(j2=1; j2<=nlstate;j2++){
                   5585:          cptj2= (j2-1)*nlstate+i2;
                   5586:          if(cptj2 <= cptj)
                   5587:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5588:        }
                   5589:     }
                   5590:   fprintf(ficrescveij,"\n");
                   5591:   
                   5592:   if(estepm < stepm){
                   5593:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5594:   }
                   5595:   else  hstepm=estepm;   
                   5596:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5597:    * This is mainly to measure the difference between two models: for example
                   5598:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5599:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5600:    * progression in between and thus overestimating or underestimating according
                   5601:    * to the curvature of the survival function. If, for the same date, we 
                   5602:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5603:    * to compare the new estimate of Life expectancy with the same linear 
                   5604:    * hypothesis. A more precise result, taking into account a more precise
                   5605:    * curvature will be obtained if estepm is as small as stepm. */
                   5606: 
                   5607:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5608:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5609:      nhstepm is the number of hstepm from age to agelim 
                   5610:      nstepm is the number of stepm from age to agelin. 
                   5611:      Look at hpijx to understand the reason of that which relies in memory size
                   5612:      and note for a fixed period like estepm months */
                   5613:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5614:      survival function given by stepm (the optimization length). Unfortunately it
                   5615:      means that if the survival funtion is printed only each two years of age and if
                   5616:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5617:      results. So we changed our mind and took the option of the best precision.
                   5618:   */
                   5619:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5620: 
                   5621:   /* If stepm=6 months */
                   5622:   /* nhstepm age range expressed in number of stepm */
                   5623:   agelim=AGESUP;
                   5624:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5625:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5626:   /* if (stepm >= YEARM) hstepm=1;*/
                   5627:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5628:   
                   5629:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5630:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5631:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5632:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5633:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5634:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5635: 
                   5636:   for (age=bage; age<=fage; age ++){ 
                   5637:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5638:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5639:     /* if (stepm >= YEARM) hstepm=1;*/
                   5640:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5641:                
1.126     brouard  5642:     /* If stepm=6 months */
                   5643:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5644:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5645:     
                   5646:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5647:                
1.126     brouard  5648:     /* Computing  Variances of health expectancies */
                   5649:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5650:        decrease memory allocation */
                   5651:     for(theta=1; theta <=npar; theta++){
                   5652:       for(i=1; i<=npar; i++){ 
1.222     brouard  5653:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5654:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5655:       }
1.235     brouard  5656:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5657:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5658:                        
1.126     brouard  5659:       for(j=1; j<= nlstate; j++){
1.222     brouard  5660:        for(i=1; i<=nlstate; i++){
                   5661:          for(h=0; h<=nhstepm-1; h++){
                   5662:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5663:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5664:          }
                   5665:        }
1.126     brouard  5666:       }
1.218     brouard  5667:                        
1.126     brouard  5668:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5669:        for(h=0; h<=nhstepm-1; h++){
                   5670:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5671:        }
1.126     brouard  5672:     }/* End theta */
                   5673:     
                   5674:     
                   5675:     for(h=0; h<=nhstepm-1; h++)
                   5676:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5677:        for(theta=1; theta <=npar; theta++)
                   5678:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5679:     
1.218     brouard  5680:                
1.222     brouard  5681:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5682:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5683:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5684:                
1.222     brouard  5685:     printf("%d|",(int)age);fflush(stdout);
                   5686:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5687:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5688:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5689:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5690:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5691:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5692:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5693:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5694:       }
                   5695:     }
1.218     brouard  5696:                
1.126     brouard  5697:     /* Computing expectancies */
1.235     brouard  5698:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5699:     for(i=1; i<=nlstate;i++)
                   5700:       for(j=1; j<=nlstate;j++)
1.222     brouard  5701:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5702:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5703:                                        
1.222     brouard  5704:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5705:                                        
1.222     brouard  5706:        }
1.269     brouard  5707: 
                   5708:     /* Standard deviation of expectancies ij */                
1.126     brouard  5709:     fprintf(ficresstdeij,"%3.0f",age );
                   5710:     for(i=1; i<=nlstate;i++){
                   5711:       eip=0.;
                   5712:       vip=0.;
                   5713:       for(j=1; j<=nlstate;j++){
1.222     brouard  5714:        eip += eij[i][j][(int)age];
                   5715:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5716:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5717:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5718:       }
                   5719:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5720:     }
                   5721:     fprintf(ficresstdeij,"\n");
1.218     brouard  5722:                
1.269     brouard  5723:     /* Variance of expectancies ij */          
1.126     brouard  5724:     fprintf(ficrescveij,"%3.0f",age );
                   5725:     for(i=1; i<=nlstate;i++)
                   5726:       for(j=1; j<=nlstate;j++){
1.222     brouard  5727:        cptj= (j-1)*nlstate+i;
                   5728:        for(i2=1; i2<=nlstate;i2++)
                   5729:          for(j2=1; j2<=nlstate;j2++){
                   5730:            cptj2= (j2-1)*nlstate+i2;
                   5731:            if(cptj2 <= cptj)
                   5732:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5733:          }
1.126     brouard  5734:       }
                   5735:     fprintf(ficrescveij,"\n");
1.218     brouard  5736:                
1.126     brouard  5737:   }
                   5738:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5739:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5740:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5741:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5742:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5743:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5744:   printf("\n");
                   5745:   fprintf(ficlog,"\n");
1.218     brouard  5746:        
1.126     brouard  5747:   free_vector(xm,1,npar);
                   5748:   free_vector(xp,1,npar);
                   5749:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5750:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5751:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5752: }
1.218     brouard  5753:  
1.126     brouard  5754: /************ Variance ******************/
1.235     brouard  5755:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5756:  {
                   5757:    /* Variance of health expectancies */
                   5758:    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
                   5759:    /* double **newm;*/
                   5760:    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
                   5761:   
                   5762:    /* int movingaverage(); */
                   5763:    double **dnewm,**doldm;
                   5764:    double **dnewmp,**doldmp;
                   5765:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5766:    int k;
                   5767:    double *xp;
                   5768:    double **gp, **gm;  /* for var eij */
                   5769:    double ***gradg, ***trgradg; /*for var eij */
                   5770:    double **gradgp, **trgradgp; /* for var p point j */
                   5771:    double *gpp, *gmp; /* for var p point j */
                   5772:    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
                   5773:    double ***p3mat;
                   5774:    double age,agelim, hf;
                   5775:    /* double ***mobaverage; */
                   5776:    int theta;
                   5777:    char digit[4];
                   5778:    char digitp[25];
                   5779: 
                   5780:    char fileresprobmorprev[FILENAMELENGTH];
                   5781: 
                   5782:    if(popbased==1){
                   5783:      if(mobilav!=0)
                   5784:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5785:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5786:    }
                   5787:    else 
                   5788:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5789: 
1.218     brouard  5790:    /* if (mobilav!=0) { */
                   5791:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5792:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5793:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5794:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5795:    /*   } */
                   5796:    /* } */
                   5797: 
                   5798:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5799:    sprintf(digit,"%-d",ij);
                   5800:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5801:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5802:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5803:    strcat(fileresprobmorprev,fileresu);
                   5804:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5805:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5806:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5807:    }
                   5808:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5809:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5810:    pstamp(ficresprobmorprev);
                   5811:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5812:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5813:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5814:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5815:    }
                   5816:    for(j=1;j<=cptcoveff;j++) 
                   5817:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5818:    fprintf(ficresprobmorprev,"\n");
                   5819: 
1.218     brouard  5820:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5821:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5822:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5823:      for(i=1; i<=nlstate;i++)
                   5824:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5825:    }  
                   5826:    fprintf(ficresprobmorprev,"\n");
                   5827:   
                   5828:    fprintf(ficgp,"\n# Routine varevsij");
                   5829:    fprintf(ficgp,"\nunset title \n");
                   5830:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5831:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5832:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
                   5833:    /*   } */
                   5834:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5835:    pstamp(ficresvij);
                   5836:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5837:    if(popbased==1)
                   5838:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5839:    else
                   5840:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5841:    fprintf(ficresvij,"# Age");
                   5842:    for(i=1; i<=nlstate;i++)
                   5843:      for(j=1; j<=nlstate;j++)
                   5844:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5845:    fprintf(ficresvij,"\n");
                   5846: 
                   5847:    xp=vector(1,npar);
                   5848:    dnewm=matrix(1,nlstate,1,npar);
                   5849:    doldm=matrix(1,nlstate,1,nlstate);
                   5850:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5851:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5852: 
                   5853:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5854:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5855:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5856:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5857:   
1.218     brouard  5858:    if(estepm < stepm){
                   5859:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5860:    }
                   5861:    else  hstepm=estepm;   
                   5862:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5863:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5864:       nhstepm is the number of hstepm from age to agelim 
                   5865:       nstepm is the number of stepm from age to agelim. 
                   5866:       Look at function hpijx to understand why because of memory size limitations, 
                   5867:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5868:       survival function given by stepm (the optimization length). Unfortunately it
                   5869:       means that if the survival funtion is printed every two years of age and if
                   5870:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5871:       results. So we changed our mind and took the option of the best precision.
                   5872:    */
                   5873:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5874:    agelim = AGESUP;
                   5875:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5876:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5877:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5878:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5879:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5880:      gp=matrix(0,nhstepm,1,nlstate);
                   5881:      gm=matrix(0,nhstepm,1,nlstate);
                   5882:                
                   5883:                
                   5884:      for(theta=1; theta <=npar; theta++){
                   5885:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5886:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5887:        }
                   5888:                        
1.242     brouard  5889:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5890:                        
                   5891:        if (popbased==1) {
                   5892:         if(mobilav ==0){
                   5893:           for(i=1; i<=nlstate;i++)
                   5894:             prlim[i][i]=probs[(int)age][i][ij];
                   5895:         }else{ /* mobilav */ 
                   5896:           for(i=1; i<=nlstate;i++)
                   5897:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5898:         }
                   5899:        }
                   5900:                        
1.235     brouard  5901:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
1.218     brouard  5902:        for(j=1; j<= nlstate; j++){
                   5903:         for(h=0; h<=nhstepm; h++){
                   5904:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5905:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5906:         }
                   5907:        }
                   5908:        /* Next for computing probability of death (h=1 means
                   5909:          computed over hstepm matrices product = hstepm*stepm months) 
                   5910:          as a weighted average of prlim.
                   5911:        */
                   5912:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5913:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   5914:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
                   5915:        }    
                   5916:        /* end probability of death */
                   5917:                        
                   5918:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   5919:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   5920:                        
1.242     brouard  5921:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  5922:                        
                   5923:        if (popbased==1) {
                   5924:         if(mobilav ==0){
                   5925:           for(i=1; i<=nlstate;i++)
                   5926:             prlim[i][i]=probs[(int)age][i][ij];
                   5927:         }else{ /* mobilav */ 
                   5928:           for(i=1; i<=nlstate;i++)
                   5929:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5930:         }
                   5931:        }
                   5932:                        
1.235     brouard  5933:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  5934:                        
                   5935:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   5936:         for(h=0; h<=nhstepm; h++){
                   5937:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   5938:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5939:         }
                   5940:        }
                   5941:        /* This for computing probability of death (h=1 means
                   5942:          computed over hstepm matrices product = hstepm*stepm months) 
                   5943:          as a weighted average of prlim.
                   5944:        */
                   5945:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   5946:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   5947:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   5948:        }    
                   5949:        /* end probability of death */
                   5950:                        
                   5951:        for(j=1; j<= nlstate; j++) /* vareij */
                   5952:         for(h=0; h<=nhstepm; h++){
                   5953:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   5954:         }
                   5955:                        
                   5956:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
                   5957:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   5958:        }
                   5959:                        
                   5960:      } /* End theta */
                   5961:                
                   5962:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   5963:                
                   5964:      for(h=0; h<=nhstepm; h++) /* veij */
                   5965:        for(j=1; j<=nlstate;j++)
                   5966:         for(theta=1; theta <=npar; theta++)
                   5967:           trgradg[h][j][theta]=gradg[h][theta][j];
                   5968:                
                   5969:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   5970:        for(theta=1; theta <=npar; theta++)
                   5971:         trgradgp[j][theta]=gradgp[theta][j];
                   5972:                
                   5973:                
                   5974:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5975:      for(i=1;i<=nlstate;i++)
                   5976:        for(j=1;j<=nlstate;j++)
                   5977:         vareij[i][j][(int)age] =0.;
                   5978:                
                   5979:      for(h=0;h<=nhstepm;h++){
                   5980:        for(k=0;k<=nhstepm;k++){
                   5981:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   5982:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   5983:         for(i=1;i<=nlstate;i++)
                   5984:           for(j=1;j<=nlstate;j++)
                   5985:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   5986:        }
                   5987:      }
                   5988:                
                   5989:      /* pptj */
                   5990:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   5991:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   5992:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   5993:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   5994:         varppt[j][i]=doldmp[j][i];
                   5995:      /* end ppptj */
                   5996:      /*  x centered again */
                   5997:                
1.242     brouard  5998:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  5999:                
                   6000:      if (popbased==1) {
                   6001:        if(mobilav ==0){
                   6002:         for(i=1; i<=nlstate;i++)
                   6003:           prlim[i][i]=probs[(int)age][i][ij];
                   6004:        }else{ /* mobilav */ 
                   6005:         for(i=1; i<=nlstate;i++)
                   6006:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6007:        }
                   6008:      }
                   6009:                
                   6010:      /* This for computing probability of death (h=1 means
                   6011:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6012:        as a weighted average of prlim.
                   6013:      */
1.235     brouard  6014:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6015:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6016:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6017:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6018:      }    
                   6019:      /* end probability of death */
                   6020:                
                   6021:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6022:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6023:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6024:        for(i=1; i<=nlstate;i++){
                   6025:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6026:        }
                   6027:      } 
                   6028:      fprintf(ficresprobmorprev,"\n");
                   6029:                
                   6030:      fprintf(ficresvij,"%.0f ",age );
                   6031:      for(i=1; i<=nlstate;i++)
                   6032:        for(j=1; j<=nlstate;j++){
                   6033:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6034:        }
                   6035:      fprintf(ficresvij,"\n");
                   6036:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6037:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6038:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6039:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6040:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6041:    } /* End age */
                   6042:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6043:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6044:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6045:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6046:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6047:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6048:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6049:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6050:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6051:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6052:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6053:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6054:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6055:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6056:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6057:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6058:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6059:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6060:     */
1.218     brouard  6061:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6062:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6063: 
1.218     brouard  6064:    free_vector(xp,1,npar);
                   6065:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6066:    free_matrix(dnewm,1,nlstate,1,npar);
                   6067:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6068:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6069:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6070:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6071:    fclose(ficresprobmorprev);
                   6072:    fflush(ficgp);
                   6073:    fflush(fichtm); 
                   6074:  }  /* end varevsij */
1.126     brouard  6075: 
                   6076: /************ Variance of prevlim ******************/
1.269     brouard  6077:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6078: {
1.205     brouard  6079:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6080:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6081: 
1.268     brouard  6082:   double **dnewmpar,**doldm;
1.126     brouard  6083:   int i, j, nhstepm, hstepm;
                   6084:   double *xp;
                   6085:   double *gp, *gm;
                   6086:   double **gradg, **trgradg;
1.208     brouard  6087:   double **mgm, **mgp;
1.126     brouard  6088:   double age,agelim;
                   6089:   int theta;
                   6090:   
                   6091:   pstamp(ficresvpl);
                   6092:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6093:   fprintf(ficresvpl,"# Age ");
                   6094:   if(nresult >=1)
                   6095:     fprintf(ficresvpl," Result# ");
1.126     brouard  6096:   for(i=1; i<=nlstate;i++)
                   6097:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6098:   fprintf(ficresvpl,"\n");
                   6099: 
                   6100:   xp=vector(1,npar);
1.268     brouard  6101:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6102:   doldm=matrix(1,nlstate,1,nlstate);
                   6103:   
                   6104:   hstepm=1*YEARM; /* Every year of age */
                   6105:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6106:   agelim = AGESUP;
                   6107:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6108:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6109:     if (stepm >= YEARM) hstepm=1;
                   6110:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6111:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6112:     mgp=matrix(1,npar,1,nlstate);
                   6113:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6114:     gp=vector(1,nlstate);
                   6115:     gm=vector(1,nlstate);
                   6116: 
                   6117:     for(theta=1; theta <=npar; theta++){
                   6118:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6119:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6120:       }
1.209     brouard  6121:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6122:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6123:       else
1.235     brouard  6124:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6125:       for(i=1;i<=nlstate;i++){
1.126     brouard  6126:        gp[i] = prlim[i][i];
1.208     brouard  6127:        mgp[theta][i] = prlim[i][i];
                   6128:       }
1.126     brouard  6129:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6130:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6131:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6132:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6133:       else
1.235     brouard  6134:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6135:       for(i=1;i<=nlstate;i++){
1.126     brouard  6136:        gm[i] = prlim[i][i];
1.208     brouard  6137:        mgm[theta][i] = prlim[i][i];
                   6138:       }
1.126     brouard  6139:       for(i=1;i<=nlstate;i++)
                   6140:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6141:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6142:     } /* End theta */
                   6143: 
                   6144:     trgradg =matrix(1,nlstate,1,npar);
                   6145: 
                   6146:     for(j=1; j<=nlstate;j++)
                   6147:       for(theta=1; theta <=npar; theta++)
                   6148:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6149:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6150:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6151:     /*   for(j=1; j<=nlstate;j++){ */
                   6152:     /*         printf(" %d ",j); */
                   6153:     /*         for(theta=1; theta <=npar; theta++) */
                   6154:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6155:     /*         printf("\n "); */
                   6156:     /*   } */
                   6157:     /* } */
                   6158:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6159:     /*   printf("\n gradg %d ",(int)age); */
                   6160:     /*   for(j=1; j<=nlstate;j++){ */
                   6161:     /*         printf("%d ",j); */
                   6162:     /*         for(theta=1; theta <=npar; theta++) */
                   6163:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6164:     /*         printf("\n "); */
                   6165:     /*   } */
                   6166:     /* } */
1.126     brouard  6167: 
                   6168:     for(i=1;i<=nlstate;i++)
                   6169:       varpl[i][(int)age] =0.;
1.209     brouard  6170:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6171:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6172:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6173:     }else{
1.268     brouard  6174:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6175:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6176:     }
1.126     brouard  6177:     for(i=1;i<=nlstate;i++)
                   6178:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6179: 
                   6180:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6181:     if(nresult >=1)
                   6182:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6183:     for(i=1; i<=nlstate;i++)
                   6184:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6185:     fprintf(ficresvpl,"\n");
                   6186:     free_vector(gp,1,nlstate);
                   6187:     free_vector(gm,1,nlstate);
1.208     brouard  6188:     free_matrix(mgm,1,npar,1,nlstate);
                   6189:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6190:     free_matrix(gradg,1,npar,1,nlstate);
                   6191:     free_matrix(trgradg,1,nlstate,1,npar);
                   6192:   } /* End age */
                   6193: 
                   6194:   free_vector(xp,1,npar);
                   6195:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6196:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6197: 
                   6198: }
                   6199: 
                   6200: 
                   6201: /************ Variance of backprevalence limit ******************/
1.269     brouard  6202:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6203: {
                   6204:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6205:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6206: 
                   6207:   double **dnewmpar,**doldm;
                   6208:   int i, j, nhstepm, hstepm;
                   6209:   double *xp;
                   6210:   double *gp, *gm;
                   6211:   double **gradg, **trgradg;
                   6212:   double **mgm, **mgp;
                   6213:   double age,agelim;
                   6214:   int theta;
                   6215:   
                   6216:   pstamp(ficresvbl);
                   6217:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6218:   fprintf(ficresvbl,"# Age ");
                   6219:   if(nresult >=1)
                   6220:     fprintf(ficresvbl," Result# ");
                   6221:   for(i=1; i<=nlstate;i++)
                   6222:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6223:   fprintf(ficresvbl,"\n");
                   6224: 
                   6225:   xp=vector(1,npar);
                   6226:   dnewmpar=matrix(1,nlstate,1,npar);
                   6227:   doldm=matrix(1,nlstate,1,nlstate);
                   6228:   
                   6229:   hstepm=1*YEARM; /* Every year of age */
                   6230:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6231:   agelim = AGEINF;
                   6232:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6233:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6234:     if (stepm >= YEARM) hstepm=1;
                   6235:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6236:     gradg=matrix(1,npar,1,nlstate);
                   6237:     mgp=matrix(1,npar,1,nlstate);
                   6238:     mgm=matrix(1,npar,1,nlstate);
                   6239:     gp=vector(1,nlstate);
                   6240:     gm=vector(1,nlstate);
                   6241: 
                   6242:     for(theta=1; theta <=npar; theta++){
                   6243:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6244:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6245:       }
                   6246:       if(mobilavproj > 0 )
                   6247:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6248:       else
                   6249:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6250:       for(i=1;i<=nlstate;i++){
                   6251:        gp[i] = bprlim[i][i];
                   6252:        mgp[theta][i] = bprlim[i][i];
                   6253:       }
                   6254:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6255:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6256:        if(mobilavproj > 0 )
                   6257:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6258:        else
                   6259:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6260:       for(i=1;i<=nlstate;i++){
                   6261:        gm[i] = bprlim[i][i];
                   6262:        mgm[theta][i] = bprlim[i][i];
                   6263:       }
                   6264:       for(i=1;i<=nlstate;i++)
                   6265:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6266:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6267:     } /* End theta */
                   6268: 
                   6269:     trgradg =matrix(1,nlstate,1,npar);
                   6270: 
                   6271:     for(j=1; j<=nlstate;j++)
                   6272:       for(theta=1; theta <=npar; theta++)
                   6273:        trgradg[j][theta]=gradg[theta][j];
                   6274:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6275:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6276:     /*   for(j=1; j<=nlstate;j++){ */
                   6277:     /*         printf(" %d ",j); */
                   6278:     /*         for(theta=1; theta <=npar; theta++) */
                   6279:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6280:     /*         printf("\n "); */
                   6281:     /*   } */
                   6282:     /* } */
                   6283:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6284:     /*   printf("\n gradg %d ",(int)age); */
                   6285:     /*   for(j=1; j<=nlstate;j++){ */
                   6286:     /*         printf("%d ",j); */
                   6287:     /*         for(theta=1; theta <=npar; theta++) */
                   6288:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6289:     /*         printf("\n "); */
                   6290:     /*   } */
                   6291:     /* } */
                   6292: 
                   6293:     for(i=1;i<=nlstate;i++)
                   6294:       varbpl[i][(int)age] =0.;
                   6295:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6296:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6297:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6298:     }else{
                   6299:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6300:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6301:     }
                   6302:     for(i=1;i<=nlstate;i++)
                   6303:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6304: 
                   6305:     fprintf(ficresvbl,"%.0f ",age );
                   6306:     if(nresult >=1)
                   6307:       fprintf(ficresvbl,"%d ",nres );
                   6308:     for(i=1; i<=nlstate;i++)
                   6309:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6310:     fprintf(ficresvbl,"\n");
                   6311:     free_vector(gp,1,nlstate);
                   6312:     free_vector(gm,1,nlstate);
                   6313:     free_matrix(mgm,1,npar,1,nlstate);
                   6314:     free_matrix(mgp,1,npar,1,nlstate);
                   6315:     free_matrix(gradg,1,npar,1,nlstate);
                   6316:     free_matrix(trgradg,1,nlstate,1,npar);
                   6317:   } /* End age */
                   6318: 
                   6319:   free_vector(xp,1,npar);
                   6320:   free_matrix(doldm,1,nlstate,1,npar);
                   6321:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6322: 
                   6323: }
                   6324: 
                   6325: /************ Variance of one-step probabilities  ******************/
                   6326: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6327:  {
                   6328:    int i, j=0,  k1, l1, tj;
                   6329:    int k2, l2, j1,  z1;
                   6330:    int k=0, l;
                   6331:    int first=1, first1, first2;
                   6332:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6333:    double **dnewm,**doldm;
                   6334:    double *xp;
                   6335:    double *gp, *gm;
                   6336:    double **gradg, **trgradg;
                   6337:    double **mu;
                   6338:    double age, cov[NCOVMAX+1];
                   6339:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6340:    int theta;
                   6341:    char fileresprob[FILENAMELENGTH];
                   6342:    char fileresprobcov[FILENAMELENGTH];
                   6343:    char fileresprobcor[FILENAMELENGTH];
                   6344:    double ***varpij;
                   6345: 
                   6346:    strcpy(fileresprob,"PROB_"); 
                   6347:    strcat(fileresprob,fileres);
                   6348:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6349:      printf("Problem with resultfile: %s\n", fileresprob);
                   6350:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6351:    }
                   6352:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6353:    strcat(fileresprobcov,fileresu);
                   6354:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6355:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6356:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6357:    }
                   6358:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6359:    strcat(fileresprobcor,fileresu);
                   6360:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6361:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6362:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6363:    }
                   6364:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6365:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6366:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6367:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6368:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6369:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6370:    pstamp(ficresprob);
                   6371:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6372:    fprintf(ficresprob,"# Age");
                   6373:    pstamp(ficresprobcov);
                   6374:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6375:    fprintf(ficresprobcov,"# Age");
                   6376:    pstamp(ficresprobcor);
                   6377:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6378:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6379: 
                   6380: 
1.222     brouard  6381:    for(i=1; i<=nlstate;i++)
                   6382:      for(j=1; j<=(nlstate+ndeath);j++){
                   6383:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6384:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6385:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6386:      }  
                   6387:    /* fprintf(ficresprob,"\n");
                   6388:       fprintf(ficresprobcov,"\n");
                   6389:       fprintf(ficresprobcor,"\n");
                   6390:    */
                   6391:    xp=vector(1,npar);
                   6392:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6393:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6394:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6395:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6396:    first=1;
                   6397:    fprintf(ficgp,"\n# Routine varprob");
                   6398:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6399:    fprintf(fichtm,"\n");
                   6400: 
1.266     brouard  6401:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6402:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6403:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6404: and drawn. It helps understanding how is the covariance between two incidences.\
                   6405:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6406:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6407: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6408: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6409: standard deviations wide on each axis. <br>\
                   6410:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6411:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6412: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6413: 
1.222     brouard  6414:    cov[1]=1;
                   6415:    /* tj=cptcoveff; */
1.225     brouard  6416:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6417:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6418:    j1=0;
1.224     brouard  6419:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6420:      if  (cptcovn>0) {
                   6421:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6422:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6423:        fprintf(ficresprob, "**********\n#\n");
                   6424:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6425:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6426:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6427:                        
1.222     brouard  6428:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6429:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6430:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6431:                        
                   6432:                        
1.222     brouard  6433:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6434:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6435:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6436:                        
1.222     brouard  6437:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6438:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6439:        fprintf(ficresprobcor, "**********\n#");    
                   6440:        if(invalidvarcomb[j1]){
                   6441:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6442:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6443:         continue;
                   6444:        }
                   6445:      }
                   6446:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6447:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6448:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6449:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6450:      for (age=bage; age<=fage; age ++){ 
                   6451:        cov[2]=age;
                   6452:        if(nagesqr==1)
                   6453:         cov[3]= age*age;
                   6454:        for (k=1; k<=cptcovn;k++) {
                   6455:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6456:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6457:                                                                    * 1  1 1 1 1
                   6458:                                                                    * 2  2 1 1 1
                   6459:                                                                    * 3  1 2 1 1
                   6460:                                                                    */
                   6461:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6462:        }
                   6463:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6464:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6465:        for (k=1; k<=cptcovprod;k++)
                   6466:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6467:                        
                   6468:                        
1.222     brouard  6469:        for(theta=1; theta <=npar; theta++){
                   6470:         for(i=1; i<=npar; i++)
                   6471:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6472:                                
1.222     brouard  6473:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6474:                                
1.222     brouard  6475:         k=0;
                   6476:         for(i=1; i<= (nlstate); i++){
                   6477:           for(j=1; j<=(nlstate+ndeath);j++){
                   6478:             k=k+1;
                   6479:             gp[k]=pmmij[i][j];
                   6480:           }
                   6481:         }
1.220     brouard  6482:                                
1.222     brouard  6483:         for(i=1; i<=npar; i++)
                   6484:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6485:                                
1.222     brouard  6486:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6487:         k=0;
                   6488:         for(i=1; i<=(nlstate); i++){
                   6489:           for(j=1; j<=(nlstate+ndeath);j++){
                   6490:             k=k+1;
                   6491:             gm[k]=pmmij[i][j];
                   6492:           }
                   6493:         }
1.220     brouard  6494:                                
1.222     brouard  6495:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6496:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6497:        }
1.126     brouard  6498: 
1.222     brouard  6499:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6500:         for(theta=1; theta <=npar; theta++)
                   6501:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6502:                        
1.222     brouard  6503:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6504:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6505:                        
1.222     brouard  6506:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6507:                        
1.222     brouard  6508:        k=0;
                   6509:        for(i=1; i<=(nlstate); i++){
                   6510:         for(j=1; j<=(nlstate+ndeath);j++){
                   6511:           k=k+1;
                   6512:           mu[k][(int) age]=pmmij[i][j];
                   6513:         }
                   6514:        }
                   6515:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6516:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6517:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6518:                        
1.222     brouard  6519:        /*printf("\n%d ",(int)age);
                   6520:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6521:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6522:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6523:         }*/
1.220     brouard  6524:                        
1.222     brouard  6525:        fprintf(ficresprob,"\n%d ",(int)age);
                   6526:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6527:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6528:                        
1.222     brouard  6529:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6530:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6531:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6532:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6533:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6534:        }
                   6535:        i=0;
                   6536:        for (k=1; k<=(nlstate);k++){
                   6537:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6538:           i++;
                   6539:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6540:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6541:           for (j=1; j<=i;j++){
                   6542:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6543:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6544:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6545:           }
                   6546:         }
                   6547:        }/* end of loop for state */
                   6548:      } /* end of loop for age */
                   6549:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6550:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6551:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6552:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6553:     
                   6554:      /* Confidence intervalle of pij  */
                   6555:      /*
                   6556:        fprintf(ficgp,"\nunset parametric;unset label");
                   6557:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6558:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6559:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6560:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6561:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6562:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6563:      */
                   6564:                
                   6565:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6566:      first1=1;first2=2;
                   6567:      for (k2=1; k2<=(nlstate);k2++){
                   6568:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6569:         if(l2==k2) continue;
                   6570:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6571:         for (k1=1; k1<=(nlstate);k1++){
                   6572:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6573:             if(l1==k1) continue;
                   6574:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6575:             if(i<=j) continue;
                   6576:             for (age=bage; age<=fage; age ++){ 
                   6577:               if ((int)age %5==0){
                   6578:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6579:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6580:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6581:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6582:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6583:                 c12=cv12/sqrt(v1*v2);
                   6584:                 /* Computing eigen value of matrix of covariance */
                   6585:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6586:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6587:                 if ((lc2 <0) || (lc1 <0) ){
                   6588:                   if(first2==1){
                   6589:                     first1=0;
                   6590:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6591:                   }
                   6592:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6593:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6594:                   /* lc2=fabs(lc2); */
                   6595:                 }
1.220     brouard  6596:                                                                
1.222     brouard  6597:                 /* Eigen vectors */
                   6598:                 v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                   6599:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6600:                 v21=(lc1-v1)/cv12*v11;
                   6601:                 v12=-v21;
                   6602:                 v22=v11;
                   6603:                 tnalp=v21/v11;
                   6604:                 if(first1==1){
                   6605:                   first1=0;
                   6606:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6607:                 }
                   6608:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6609:                 /*printf(fignu*/
                   6610:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6611:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6612:                 if(first==1){
                   6613:                   first=0;
                   6614:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6615:                   fprintf(ficgp,"\nset parametric;unset label");
                   6616:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6617:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6618:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6619:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6620: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6621:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6622:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6623:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6624:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6625:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6626:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6627:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6628:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.266     brouard  6629:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6630:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6631:                 }else{
                   6632:                   first=0;
                   6633:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6634:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6635:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6636:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6637:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6638:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6639:                 }/* if first */
                   6640:               } /* age mod 5 */
                   6641:             } /* end loop age */
                   6642:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6643:             first=1;
                   6644:           } /*l12 */
                   6645:         } /* k12 */
                   6646:        } /*l1 */
                   6647:      }/* k1 */
                   6648:    }  /* loop on combination of covariates j1 */
                   6649:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6650:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6651:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6652:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6653:    free_vector(xp,1,npar);
                   6654:    fclose(ficresprob);
                   6655:    fclose(ficresprobcov);
                   6656:    fclose(ficresprobcor);
                   6657:    fflush(ficgp);
                   6658:    fflush(fichtmcov);
                   6659:  }
1.126     brouard  6660: 
                   6661: 
                   6662: /******************* Printing html file ***********/
1.201     brouard  6663: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6664:                  int lastpass, int stepm, int weightopt, char model[],\
                   6665:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6666:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273   ! brouard  6667:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
        !          6668:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6669:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6670: 
                   6671:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6672:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6673: </ul>");
1.237     brouard  6674:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6675: </ul>", model);
1.214     brouard  6676:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6677:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6678:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6679:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6680:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6681:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6682:    fprintf(fichtm,"\
                   6683:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6684:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6685:    fprintf(fichtm,"\
1.217     brouard  6686:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6687:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6688:    fprintf(fichtm,"\
1.126     brouard  6689:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6690:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6691:    fprintf(fichtm,"\
1.217     brouard  6692:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6693:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6694:    fprintf(fichtm,"\
1.211     brouard  6695:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6696:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6697:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6698:    if(prevfcast==1){
                   6699:      fprintf(fichtm,"\
                   6700:  - Prevalence projections by age and states:                           \
1.201     brouard  6701:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6702:    }
1.126     brouard  6703: 
                   6704: 
1.225     brouard  6705:    m=pow(2,cptcoveff);
1.222     brouard  6706:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6707: 
1.264     brouard  6708:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6709: 
                   6710:    jj1=0;
                   6711: 
                   6712:    fprintf(fichtm," \n<ul>");
                   6713:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6714:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6715:      if(m != 1 && TKresult[nres]!= k1)
                   6716:        continue;
                   6717:      jj1++;
                   6718:      if (cptcovn > 0) {
                   6719:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6720:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6721:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6722:        }
                   6723:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6724:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6725:        }
                   6726:        fprintf(fichtm,"\">");
                   6727:        
                   6728:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6729:        fprintf(fichtm,"************ Results for covariates");
                   6730:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6731:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6732:        }
                   6733:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6734:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6735:        }
                   6736:        if(invalidvarcomb[k1]){
                   6737:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6738:         continue;
                   6739:        }
                   6740:        fprintf(fichtm,"</a></li>");
                   6741:      } /* cptcovn >0 */
                   6742:    }
                   6743:      fprintf(fichtm," \n</ul>");
                   6744: 
1.222     brouard  6745:    jj1=0;
1.237     brouard  6746: 
                   6747:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6748:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6749:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6750:        continue;
1.220     brouard  6751: 
1.222     brouard  6752:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6753:      jj1++;
                   6754:      if (cptcovn > 0) {
1.264     brouard  6755:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6756:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6757:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6758:        }
                   6759:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6760:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6761:        }
                   6762:        fprintf(fichtm,"\"</a>");
                   6763:  
1.222     brouard  6764:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6765:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6766:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6767:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6768:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6769:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6770:        }
1.237     brouard  6771:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6772:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6773:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6774:       }
                   6775:        
1.230     brouard  6776:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6777:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6778:        if(invalidvarcomb[k1]){
                   6779:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6780:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6781:         continue;
                   6782:        }
                   6783:      }
                   6784:      /* aij, bij */
1.259     brouard  6785:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6786: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6787:      /* Pij */
1.241     brouard  6788:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6789: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6790:      /* Quasi-incidences */
                   6791:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6792:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6793:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6794: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6795: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6796:      /* Survival functions (period) in state j */
                   6797:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6798:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6799: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6800:      }
                   6801:      /* State specific survival functions (period) */
                   6802:      for(cpt=1; cpt<=nlstate;cpt++){
                   6803:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6804:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.241     brouard  6805:  <a href=\"%s_%d-%d-%d.svg\">%s_%d%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6806:      }
                   6807:      /* Period (stable) prevalence in each health state */
                   6808:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6809:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6810: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6811:      }
                   6812:      if(backcast==1){
                   6813:        /* Period (stable) back prevalence in each health state */
                   6814:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6815:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6816: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6817:        }
1.217     brouard  6818:      }
1.222     brouard  6819:      if(prevfcast==1){
                   6820:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6821:        for(cpt=1; cpt<=nlstate;cpt++){
1.273   ! brouard  6822:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
        !          6823: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6824:        }
                   6825:      }
1.268     brouard  6826:      if(backcast==1){
                   6827:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6828:        for(cpt=1; cpt<=nlstate;cpt++){
1.273   ! brouard  6829:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
        !          6830:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
        !          6831:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
        !          6832: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
        !          6833:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6834:        }
                   6835:      }
1.220     brouard  6836:         
1.222     brouard  6837:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6838:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6839: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6840:      }
                   6841:      /* } /\* end i1 *\/ */
                   6842:    }/* End k1 */
                   6843:    fprintf(fichtm,"</ul>");
1.126     brouard  6844: 
1.222     brouard  6845:    fprintf(fichtm,"\
1.126     brouard  6846: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6847:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6848:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6849: But because parameters are usually highly correlated (a higher incidence of disability \
                   6850: and a higher incidence of recovery can give very close observed transition) it might \
                   6851: be very useful to look not only at linear confidence intervals estimated from the \
                   6852: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6853: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6854: covariance matrix of the one-step probabilities. \
                   6855: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6856: 
1.222     brouard  6857:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6858:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6859:    fprintf(fichtm,"\
1.126     brouard  6860:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6861:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6862: 
1.222     brouard  6863:    fprintf(fichtm,"\
1.126     brouard  6864:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6865:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6866:    fprintf(fichtm,"\
1.126     brouard  6867:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6868:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6869:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6870:    fprintf(fichtm,"\
1.126     brouard  6871:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6872:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6873:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6874:    fprintf(fichtm,"\
1.128     brouard  6875:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6876:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6877:    fprintf(fichtm,"\
1.128     brouard  6878:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6879:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6880:    fprintf(fichtm,"\
1.126     brouard  6881:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6882:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6883: 
                   6884: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6885: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6886: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6887: /*     <br>",fileres,fileres,fileres,fileres); */
                   6888: /*  else  */
                   6889: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  6890:    fflush(fichtm);
                   6891:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  6892: 
1.225     brouard  6893:    m=pow(2,cptcoveff);
1.222     brouard  6894:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6895: 
1.222     brouard  6896:    jj1=0;
1.237     brouard  6897: 
1.241     brouard  6898:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  6899:    for(k1=1; k1<=m;k1++){
1.253     brouard  6900:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6901:        continue;
1.222     brouard  6902:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6903:      jj1++;
1.126     brouard  6904:      if (cptcovn > 0) {
                   6905:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6906:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  6907:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   6908:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6909:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6910:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6911:       }
                   6912: 
1.126     brouard  6913:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6914: 
1.222     brouard  6915:        if(invalidvarcomb[k1]){
                   6916:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   6917:         continue;
                   6918:        }
1.126     brouard  6919:      }
                   6920:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  6921:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  6922: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  6923: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  6924:      }
                   6925:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  6926: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   6927: true period expectancies (those weighted with period prevalences are also\
                   6928:  drawn in addition to the population based expectancies computed using\
1.241     brouard  6929:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   6930: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  6931:      /* } /\* end i1 *\/ */
                   6932:    }/* End k1 */
1.241     brouard  6933:   }/* End nres */
1.222     brouard  6934:    fprintf(fichtm,"</ul>");
                   6935:    fflush(fichtm);
1.126     brouard  6936: }
                   6937: 
                   6938: /******************* Gnuplot file **************/
1.270     brouard  6939: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  6940: 
                   6941:   char dirfileres[132],optfileres[132];
1.264     brouard  6942:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  6943:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  6944:   int lv=0, vlv=0, kl=0;
1.130     brouard  6945:   int ng=0;
1.201     brouard  6946:   int vpopbased;
1.223     brouard  6947:   int ioffset; /* variable offset for columns */
1.270     brouard  6948:   int iyearc=1; /* variable column for year of projection  */
                   6949:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  6950:   int nres=0; /* Index of resultline */
1.266     brouard  6951:   int istart=1; /* For starting graphs in projections */
1.219     brouard  6952: 
1.126     brouard  6953: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   6954: /*     printf("Problem with file %s",optionfilegnuplot); */
                   6955: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   6956: /*   } */
                   6957: 
                   6958:   /*#ifdef windows */
                   6959:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  6960:   /*#endif */
1.225     brouard  6961:   m=pow(2,cptcoveff);
1.126     brouard  6962: 
1.202     brouard  6963:   /* Contribution to likelihood */
                   6964:   /* Plot the probability implied in the likelihood */
1.223     brouard  6965:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   6966:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   6967:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   6968:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  6969: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  6970:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   6971: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  6972:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   6973:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6974:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   6975:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   6976:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   6977:   for (i=1; i<= nlstate ; i ++) {
                   6978:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   6979:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   6980:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   6981:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   6982:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   6983:     }
                   6984:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   6985:   }
                   6986:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   6987:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   6988:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   6989:   fprintf(ficgp,"\nset out;unset log\n");
                   6990:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  6991: 
1.126     brouard  6992:   strcpy(dirfileres,optionfilefiname);
                   6993:   strcpy(optfileres,"vpl");
1.223     brouard  6994:   /* 1eme*/
1.238     brouard  6995:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   6996:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  6997:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  6998:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  6999:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7000:          continue;
                   7001:        /* We are interested in selected combination by the resultline */
1.246     brouard  7002:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  7003:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7004:        strcpy(gplotlabel,"(");
1.238     brouard  7005:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7006:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7007:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7008:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7009:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7010:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7011:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7012:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7013:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7014:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7015:        }
                   7016:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7017:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7018:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7019:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7020:        }
                   7021:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7022:        /* printf("\n#\n"); */
1.238     brouard  7023:        fprintf(ficgp,"\n#\n");
                   7024:        if(invalidvarcomb[k1]){
1.260     brouard  7025:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7026:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7027:          continue;
                   7028:        }
1.235     brouard  7029:       
1.241     brouard  7030:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7031:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.264     brouard  7032:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7033:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7034:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7035:       /* k1-1 error should be nres-1*/
1.238     brouard  7036:        for (i=1; i<= nlstate ; i ++) {
                   7037:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7038:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7039:        }
1.260     brouard  7040:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7041:        for (i=1; i<= nlstate ; i ++) {
                   7042:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7043:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7044:        } 
1.260     brouard  7045:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7046:        for (i=1; i<= nlstate ; i ++) {
                   7047:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7048:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7049:        }  
1.265     brouard  7050:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7051:        
                   7052:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7053:         if(cptcoveff ==0){
1.271     brouard  7054:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7055:        }else{
                   7056:          kl=0;
                   7057:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7058:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7059:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7060:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7061:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7062:            vlv= nbcode[Tvaraff[k]][lv];
                   7063:            kl++;
                   7064:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7065:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7066:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7067:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7068:            if(k==cptcoveff){
                   7069:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7070:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7071:            }else{
                   7072:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7073:              kl++;
                   7074:            }
                   7075:          } /* end covariate */
                   7076:        } /* end if no covariate */
                   7077: 
1.238     brouard  7078:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7079:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7080:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7081:          if(cptcoveff ==0){
1.245     brouard  7082:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7083:          }else{
                   7084:            kl=0;
                   7085:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7086:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7087:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7088:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7089:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7090:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7091:              kl++;
1.238     brouard  7092:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7093:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7094:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7095:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7096:              if(k==cptcoveff){
1.245     brouard  7097:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7098:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7099:              }else{
                   7100:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7101:                kl++;
                   7102:              }
                   7103:            } /* end covariate */
                   7104:          } /* end if no covariate */
1.268     brouard  7105:          if(backcast == 1){
                   7106:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7107:            /* k1-1 error should be nres-1*/
                   7108:            for (i=1; i<= nlstate ; i ++) {
                   7109:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7110:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7111:            }
1.271     brouard  7112:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7113:            for (i=1; i<= nlstate ; i ++) {
                   7114:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7115:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7116:            } 
1.272     brouard  7117:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 5,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7118:            for (i=1; i<= nlstate ; i ++) {
                   7119:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7120:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7121:            } 
1.272     brouard  7122:            fprintf(ficgp,"\" t\"\" w l lt 5");
1.268     brouard  7123:          } /* end if backprojcast */
1.238     brouard  7124:        } /* end if backcast */
1.264     brouard  7125:        fprintf(ficgp,"\nset out ;unset label;\n");
1.238     brouard  7126:       } /* nres */
1.201     brouard  7127:     } /* k1 */
                   7128:   } /* cpt */
1.235     brouard  7129: 
                   7130:   
1.126     brouard  7131:   /*2 eme*/
1.238     brouard  7132:   for (k1=1; k1<= m ; k1 ++){  
                   7133:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7134:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7135:        continue;
                   7136:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7137:       strcpy(gplotlabel,"(");
1.238     brouard  7138:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7139:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7140:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7141:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7142:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7143:        vlv= nbcode[Tvaraff[k]][lv];
                   7144:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7145:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7146:       }
1.237     brouard  7147:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7148:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7149:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7150:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7151:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7152:       }
1.264     brouard  7153:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7154:       fprintf(ficgp,"\n#\n");
1.223     brouard  7155:       if(invalidvarcomb[k1]){
                   7156:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7157:        continue;
                   7158:       }
1.219     brouard  7159:                        
1.241     brouard  7160:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7161:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7162:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7163:        if(vpopbased==0){
1.238     brouard  7164:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7165:        }else
1.238     brouard  7166:          fprintf(ficgp,"\nreplot ");
                   7167:        for (i=1; i<= nlstate+1 ; i ++) {
                   7168:          k=2*i;
1.261     brouard  7169:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7170:          for (j=1; j<= nlstate+1 ; j ++) {
                   7171:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7172:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7173:          }   
                   7174:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7175:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7176:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7177:          for (j=1; j<= nlstate+1 ; j ++) {
                   7178:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7179:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7180:          }   
                   7181:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7182:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7183:          for (j=1; j<= nlstate+1 ; j ++) {
                   7184:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7185:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7186:          }   
                   7187:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7188:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7189:        } /* state */
                   7190:       } /* vpopbased */
1.264     brouard  7191:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7192:     } /* end nres */
                   7193:   } /* k1 end 2 eme*/
                   7194:        
                   7195:        
                   7196:   /*3eme*/
                   7197:   for (k1=1; k1<= m ; k1 ++){
                   7198:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7199:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7200:        continue;
                   7201: 
                   7202:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7203:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7204:        strcpy(gplotlabel,"(");
1.238     brouard  7205:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7206:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7207:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7208:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7209:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7210:          vlv= nbcode[Tvaraff[k]][lv];
                   7211:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7212:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7213:        }
                   7214:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7215:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7216:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7217:        }       
1.264     brouard  7218:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7219:        fprintf(ficgp,"\n#\n");
                   7220:        if(invalidvarcomb[k1]){
                   7221:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7222:          continue;
                   7223:        }
                   7224:                        
                   7225:        /*       k=2+nlstate*(2*cpt-2); */
                   7226:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7227:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7228:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7229:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7230: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7231:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7232:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7233:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7234:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7235:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7236:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7237:                                
1.238     brouard  7238:        */
                   7239:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7240:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7241:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7242:                                
1.238     brouard  7243:        } 
1.261     brouard  7244:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7245:       }
1.264     brouard  7246:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7247:     } /* end nres */
                   7248:   } /* end kl 3eme */
1.126     brouard  7249:   
1.223     brouard  7250:   /* 4eme */
1.201     brouard  7251:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7252:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7253:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7254:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7255:        continue;
1.238     brouard  7256:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7257:        strcpy(gplotlabel,"(");
1.238     brouard  7258:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7259:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7260:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7261:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7262:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7263:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7264:          vlv= nbcode[Tvaraff[k]][lv];
                   7265:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7266:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7267:        }
                   7268:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7269:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7270:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7271:        }       
1.264     brouard  7272:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7273:        fprintf(ficgp,"\n#\n");
                   7274:        if(invalidvarcomb[k1]){
                   7275:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7276:          continue;
1.223     brouard  7277:        }
1.238     brouard  7278:       
1.241     brouard  7279:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7280:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7281:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7282: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7283:        k=3;
                   7284:        for (i=1; i<= nlstate ; i ++){
                   7285:          if(i==1){
                   7286:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7287:          }else{
                   7288:            fprintf(ficgp,", '' ");
                   7289:          }
                   7290:          l=(nlstate+ndeath)*(i-1)+1;
                   7291:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7292:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7293:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7294:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7295:        } /* nlstate */
1.264     brouard  7296:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7297:       } /* end cpt state*/ 
                   7298:     } /* end nres */
                   7299:   } /* end covariate k1 */  
                   7300: 
1.220     brouard  7301: /* 5eme */
1.201     brouard  7302:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7303:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7304:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7305:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7306:        continue;
1.238     brouard  7307:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7308:        strcpy(gplotlabel,"(");
1.238     brouard  7309:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7310:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7311:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7312:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7313:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7314:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7315:          vlv= nbcode[Tvaraff[k]][lv];
                   7316:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7317:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7318:        }
                   7319:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7320:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7321:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7322:        }       
1.264     brouard  7323:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7324:        fprintf(ficgp,"\n#\n");
                   7325:        if(invalidvarcomb[k1]){
                   7326:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7327:          continue;
                   7328:        }
1.227     brouard  7329:       
1.241     brouard  7330:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7331:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7332:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7333: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7334:        k=3;
                   7335:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7336:          if(j==1)
                   7337:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7338:          else
                   7339:            fprintf(ficgp,", '' ");
                   7340:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7341:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7342:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7343:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7344:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7345:        } /* nlstate */
                   7346:        fprintf(ficgp,", '' ");
                   7347:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7348:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7349:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7350:          if(j < nlstate)
                   7351:            fprintf(ficgp,"$%d +",k+l);
                   7352:          else
                   7353:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7354:        }
1.264     brouard  7355:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7356:       } /* end cpt state*/ 
                   7357:     } /* end covariate */  
                   7358:   } /* end nres */
1.227     brouard  7359:   
1.220     brouard  7360: /* 6eme */
1.202     brouard  7361:   /* CV preval stable (period) for each covariate */
1.237     brouard  7362:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7363:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7364:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7365:       continue;
1.255     brouard  7366:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7367:       strcpy(gplotlabel,"(");      
1.211     brouard  7368:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7369:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7370:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7371:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7372:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7373:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7374:        vlv= nbcode[Tvaraff[k]][lv];
                   7375:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7376:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7377:       }
1.237     brouard  7378:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7379:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7380:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7381:       }        
1.264     brouard  7382:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7383:       fprintf(ficgp,"\n#\n");
1.223     brouard  7384:       if(invalidvarcomb[k1]){
1.227     brouard  7385:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7386:        continue;
1.223     brouard  7387:       }
1.227     brouard  7388:       
1.241     brouard  7389:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7390:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7391:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7392: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7393:       k=3; /* Offset */
1.255     brouard  7394:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7395:        if(i==1)
                   7396:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7397:        else
                   7398:          fprintf(ficgp,", '' ");
1.255     brouard  7399:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7400:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7401:        for (j=2; j<= nlstate ; j ++)
                   7402:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7403:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7404:       } /* nlstate */
1.264     brouard  7405:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7406:     } /* end cpt state*/ 
                   7407:   } /* end covariate */  
1.227     brouard  7408:   
                   7409:   
1.220     brouard  7410: /* 7eme */
1.218     brouard  7411:   if(backcast == 1){
1.217     brouard  7412:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7413:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7414:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7415:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7416:        continue;
1.268     brouard  7417:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7418:        strcpy(gplotlabel,"(");      
                   7419:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7420:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7421:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7422:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7423:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7424:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7425:          vlv= nbcode[Tvaraff[k]][lv];
                   7426:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7427:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7428:        }
1.237     brouard  7429:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7430:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7431:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7432:        }       
1.264     brouard  7433:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7434:        fprintf(ficgp,"\n#\n");
                   7435:        if(invalidvarcomb[k1]){
                   7436:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7437:          continue;
                   7438:        }
                   7439:        
1.241     brouard  7440:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7441:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7442:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7443: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7444:        k=3; /* Offset */
1.268     brouard  7445:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7446:          if(i==1)
                   7447:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7448:          else
                   7449:            fprintf(ficgp,", '' ");
                   7450:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7451:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7452:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7453:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7454:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7455:          /* for (j=2; j<= nlstate ; j ++) */
                   7456:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7457:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7458:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7459:        } /* nlstate */
1.264     brouard  7460:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7461:       } /* end cpt state*/ 
                   7462:     } /* end covariate */  
                   7463:   } /* End if backcast */
                   7464:   
1.223     brouard  7465:   /* 8eme */
1.218     brouard  7466:   if(prevfcast==1){
                   7467:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7468:     
1.237     brouard  7469:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7470:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7471:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7472:        continue;
1.211     brouard  7473:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7474:        strcpy(gplotlabel,"(");      
1.227     brouard  7475:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7476:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7477:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7478:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7479:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7480:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7481:          vlv= nbcode[Tvaraff[k]][lv];
                   7482:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7483:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7484:        }
1.237     brouard  7485:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7486:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7487:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7488:        }       
1.264     brouard  7489:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7490:        fprintf(ficgp,"\n#\n");
                   7491:        if(invalidvarcomb[k1]){
                   7492:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7493:          continue;
                   7494:        }
                   7495:        
                   7496:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7497:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7498:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7499:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7500: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7501: 
                   7502:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7503:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7504:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7505:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7506:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7507:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7508:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7509:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7510:          if(i==istart){
1.227     brouard  7511:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7512:          }else{
                   7513:            fprintf(ficgp,",\\\n '' ");
                   7514:          }
                   7515:          if(cptcoveff ==0){ /* No covariate */
                   7516:            ioffset=2; /* Age is in 2 */
                   7517:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7518:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7519:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7520:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7521:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7522:            if(i==nlstate+1){
1.270     brouard  7523:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7524:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7525:              fprintf(ficgp,",\\\n '' ");
                   7526:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7527:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7528:                     offyear,                           \
1.268     brouard  7529:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7530:            }else
1.227     brouard  7531:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7532:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7533:          }else{ /* more than 2 covariates */
1.270     brouard  7534:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7535:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7536:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7537:            iyearc=ioffset-1;
                   7538:            iagec=ioffset;
1.227     brouard  7539:            fprintf(ficgp," u %d:(",ioffset); 
                   7540:            kl=0;
                   7541:            strcpy(gplotcondition,"(");
                   7542:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7543:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7544:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7545:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7546:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7547:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7548:              kl++;
                   7549:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7550:              kl++;
                   7551:              if(k <cptcoveff && cptcoveff>1)
                   7552:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7553:            }
                   7554:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7555:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7556:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7557:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7558:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7559:            if(i==nlstate+1){
1.270     brouard  7560:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7561:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7562:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7563:              fprintf(ficgp," u %d:(",iagec); 
                   7564:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7565:                      iyearc, iagec, offyear,                           \
                   7566:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7567: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7568:            }else{
                   7569:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7570:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7571:            }
                   7572:          } /* end if covariate */
                   7573:        } /* nlstate */
1.264     brouard  7574:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7575:       } /* end cpt state*/
                   7576:     } /* end covariate */
                   7577:   } /* End if prevfcast */
1.227     brouard  7578:   
1.268     brouard  7579:   if(backcast==1){
                   7580:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7581:     
                   7582:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7583:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7584:       if(m != 1 && TKresult[nres]!= k1)
                   7585:        continue;
                   7586:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7587:        strcpy(gplotlabel,"(");      
                   7588:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7589:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7590:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7591:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7592:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7593:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7594:          vlv= nbcode[Tvaraff[k]][lv];
                   7595:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7596:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7597:        }
                   7598:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7599:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7600:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7601:        }       
                   7602:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7603:        fprintf(ficgp,"\n#\n");
                   7604:        if(invalidvarcomb[k1]){
                   7605:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7606:          continue;
                   7607:        }
                   7608:        
                   7609:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7610:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7611:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7612:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7613: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7614: 
                   7615:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7616:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7617:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7618:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7619:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7620:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7621:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7622:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7623:          if(i==istart){
                   7624:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7625:          }else{
                   7626:            fprintf(ficgp,",\\\n '' ");
                   7627:          }
                   7628:          if(cptcoveff ==0){ /* No covariate */
                   7629:            ioffset=2; /* Age is in 2 */
                   7630:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7631:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7632:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7633:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7634:            fprintf(ficgp," u %d:(", ioffset); 
                   7635:            if(i==nlstate+1){
1.270     brouard  7636:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7637:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7638:              fprintf(ficgp,",\\\n '' ");
                   7639:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7640:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7641:                     offbyear,                          \
                   7642:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7643:            }else
                   7644:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7645:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7646:          }else{ /* more than 2 covariates */
1.270     brouard  7647:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7648:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7649:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7650:            iyearc=ioffset-1;
                   7651:            iagec=ioffset;
1.268     brouard  7652:            fprintf(ficgp," u %d:(",ioffset); 
                   7653:            kl=0;
                   7654:            strcpy(gplotcondition,"(");
                   7655:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7656:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7657:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7658:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7659:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7660:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7661:              kl++;
                   7662:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7663:              kl++;
                   7664:              if(k <cptcoveff && cptcoveff>1)
                   7665:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7666:            }
                   7667:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7668:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7669:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7670:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7671:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7672:            if(i==nlstate+1){
1.270     brouard  7673:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7674:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7675:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7676:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7677:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7678:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7679:                      iyearc,iagec,offbyear,                            \
                   7680:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7681: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7682:            }else{
                   7683:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7684:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7685:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7686:            }
                   7687:          } /* end if covariate */
                   7688:        } /* nlstate */
                   7689:        fprintf(ficgp,"\nset out; unset label;\n");
                   7690:       } /* end cpt state*/
                   7691:     } /* end covariate */
                   7692:   } /* End if backcast */
                   7693:   
1.227     brouard  7694:   
1.238     brouard  7695:   /* 9eme writing MLE parameters */
                   7696:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7697:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7698:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7699:     for(k=1; k <=(nlstate+ndeath); k++){
                   7700:       if (k != i) {
1.227     brouard  7701:        fprintf(ficgp,"#   current state %d\n",k);
                   7702:        for(j=1; j <=ncovmodel; j++){
                   7703:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7704:          jk++; 
                   7705:        }
                   7706:        fprintf(ficgp,"\n");
1.126     brouard  7707:       }
                   7708:     }
1.223     brouard  7709:   }
1.187     brouard  7710:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7711:   
1.145     brouard  7712:   /*goto avoid;*/
1.238     brouard  7713:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7714:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7715:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7716:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7717:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7718:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7719:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7720:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7721:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7722:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7723:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7724:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7725:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7726:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7727:   fprintf(ficgp,"#\n");
1.223     brouard  7728:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7729:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7730:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7731:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7732:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7733:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7734:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7735:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7736:        continue;
1.264     brouard  7737:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7738:       strcpy(gplotlabel,"(");
                   7739:       sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);
                   7740:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7741:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7742:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7743:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7744:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7745:        vlv= nbcode[Tvaraff[k]][lv];
                   7746:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7747:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7748:       }
1.237     brouard  7749:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7750:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7751:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7752:       }        
1.264     brouard  7753:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7754:       fprintf(ficgp,"\n#\n");
1.264     brouard  7755:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
                   7756:       fprintf(ficgp,"\nset label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7757:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7758:       if (ng==1){
                   7759:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7760:        fprintf(ficgp,"\nunset log y");
                   7761:       }else if (ng==2){
                   7762:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7763:        fprintf(ficgp,"\nset log y");
                   7764:       }else if (ng==3){
                   7765:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7766:        fprintf(ficgp,"\nset log y");
                   7767:       }else
                   7768:        fprintf(ficgp,"\nunset title ");
                   7769:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7770:       i=1;
                   7771:       for(k2=1; k2<=nlstate; k2++) {
                   7772:        k3=i;
                   7773:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7774:          if (k != k2){
                   7775:            switch( ng) {
                   7776:            case 1:
                   7777:              if(nagesqr==0)
                   7778:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7779:              else /* nagesqr =1 */
                   7780:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7781:              break;
                   7782:            case 2: /* ng=2 */
                   7783:              if(nagesqr==0)
                   7784:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7785:              else /* nagesqr =1 */
                   7786:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7787:              break;
                   7788:            case 3:
                   7789:              if(nagesqr==0)
                   7790:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7791:              else /* nagesqr =1 */
                   7792:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7793:              break;
                   7794:            }
                   7795:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7796:            ijp=1; /* product no age */
                   7797:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7798:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7799:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7800:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7801:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7802:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7803:                    if(DummyV[j]==0){
                   7804:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7805:                    }else{ /* quantitative */
                   7806:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7807:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7808:                    }
                   7809:                    ij++;
1.237     brouard  7810:                  }
1.268     brouard  7811:                } 
                   7812:              }else if(cptcovprod >0){
                   7813:                if(j==Tprod[ijp]) { /* */ 
                   7814:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7815:                  if(ijp <=cptcovprod) { /* Product */
                   7816:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7817:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7818:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7819:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7820:                      }else{ /* Vn is dummy and Vm is quanti */
                   7821:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7822:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7823:                      }
                   7824:                    }else{ /* Vn*Vm Vn is quanti */
                   7825:                      if(DummyV[Tvard[ijp][2]]==0){
                   7826:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7827:                      }else{ /* Both quanti */
                   7828:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7829:                      }
1.237     brouard  7830:                    }
1.268     brouard  7831:                    ijp++;
1.237     brouard  7832:                  }
1.268     brouard  7833:                } /* end Tprod */
1.237     brouard  7834:              } else{  /* simple covariate */
1.264     brouard  7835:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7836:                if(Dummy[j]==0){
                   7837:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7838:                }else{ /* quantitative */
                   7839:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7840:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7841:                }
1.237     brouard  7842:              } /* end simple */
                   7843:            } /* end j */
1.223     brouard  7844:          }else{
                   7845:            i=i-ncovmodel;
                   7846:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7847:              fprintf(ficgp," (1.");
                   7848:          }
1.227     brouard  7849:          
1.223     brouard  7850:          if(ng != 1){
                   7851:            fprintf(ficgp,")/(1");
1.227     brouard  7852:            
1.264     brouard  7853:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7854:              if(nagesqr==0)
1.264     brouard  7855:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7856:              else /* nagesqr =1 */
1.264     brouard  7857:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7858:               
1.223     brouard  7859:              ij=1;
                   7860:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7861:                 if(cptcovage >0){ 
                   7862:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7863:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7864:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7865:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7866:                       ij++;
                   7867:                     }
                   7868:                   }
                   7869:                 }else
                   7870:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7871:              }
                   7872:              fprintf(ficgp,")");
                   7873:            }
                   7874:            fprintf(ficgp,")");
                   7875:            if(ng ==2)
                   7876:              fprintf(ficgp," t \"p%d%d\" ", k2,k);
                   7877:            else /* ng= 3 */
                   7878:              fprintf(ficgp," t \"i%d%d\" ", k2,k);
                   7879:          }else{ /* end ng <> 1 */
                   7880:            if( k !=k2) /* logit p11 is hard to draw */
                   7881:              fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                   7882:          }
                   7883:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   7884:            fprintf(ficgp,",");
                   7885:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   7886:            fprintf(ficgp,",");
                   7887:          i=i+ncovmodel;
                   7888:        } /* end k */
                   7889:       } /* end k2 */
1.264     brouard  7890:       fprintf(ficgp,"\n set out; unset label;\n");
                   7891:     } /* end k1 */
1.223     brouard  7892:   } /* end ng */
                   7893:   /* avoid: */
                   7894:   fflush(ficgp); 
1.126     brouard  7895: }  /* end gnuplot */
                   7896: 
                   7897: 
                   7898: /*************** Moving average **************/
1.219     brouard  7899: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  7900:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  7901:    
1.222     brouard  7902:    int i, cpt, cptcod;
                   7903:    int modcovmax =1;
                   7904:    int mobilavrange, mob;
                   7905:    int iage=0;
                   7906: 
1.266     brouard  7907:    double sum=0., sumr=0.;
1.222     brouard  7908:    double age;
1.266     brouard  7909:    double *sumnewp, *sumnewm, *sumnewmr;
                   7910:    double *agemingood, *agemaxgood; 
                   7911:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  7912:   
                   7913:   
1.225     brouard  7914:    /* modcovmax=2*cptcoveff;/\* Max number of modalities. We suppose  */
1.222     brouard  7915:    /*             a covariate has 2 modalities, should be equal to ncovcombmax  *\/ */
                   7916: 
                   7917:    sumnewp = vector(1,ncovcombmax);
                   7918:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  7919:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  7920:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  7921:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  7922:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  7923:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  7924: 
                   7925:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  7926:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  7927:      sumnewp[cptcod]=0.;
1.266     brouard  7928:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   7929:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  7930:    }
                   7931:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   7932:   
1.266     brouard  7933:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   7934:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  7935:      else mobilavrange=mobilav;
                   7936:      for (age=bage; age<=fage; age++)
                   7937:        for (i=1; i<=nlstate;i++)
                   7938:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   7939:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   7940:      /* We keep the original values on the extreme ages bage, fage and for 
                   7941:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   7942:        we use a 5 terms etc. until the borders are no more concerned. 
                   7943:      */ 
                   7944:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   7945:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  7946:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   7947:           sumnewm[cptcod]=0.;
                   7948:           for (i=1; i<=nlstate;i++){
1.222     brouard  7949:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   7950:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   7951:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   7952:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   7953:             }
                   7954:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  7955:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7956:           } /* end i */
                   7957:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   7958:         } /* end cptcod */
1.222     brouard  7959:        }/* end age */
                   7960:      }/* end mob */
1.266     brouard  7961:    }else{
                   7962:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  7963:      return -1;
1.266     brouard  7964:    }
                   7965: 
                   7966:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  7967:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   7968:      if(invalidvarcomb[cptcod]){
                   7969:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   7970:        continue;
                   7971:      }
1.219     brouard  7972: 
1.266     brouard  7973:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   7974:        sumnewm[cptcod]=0.;
                   7975:        sumnewmr[cptcod]=0.;
                   7976:        for (i=1; i<=nlstate;i++){
                   7977:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   7978:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7979:        }
                   7980:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7981:         agemingoodr[cptcod]=age;
                   7982:        }
                   7983:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   7984:           agemingood[cptcod]=age;
                   7985:        }
                   7986:      } /* age */
                   7987:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  7988:        sumnewm[cptcod]=0.;
1.266     brouard  7989:        sumnewmr[cptcod]=0.;
1.222     brouard  7990:        for (i=1; i<=nlstate;i++){
                   7991:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  7992:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   7993:        }
                   7994:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   7995:         agemaxgoodr[cptcod]=age;
1.222     brouard  7996:        }
                   7997:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  7998:         agemaxgood[cptcod]=age;
                   7999:        }
                   8000:      } /* age */
                   8001:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8002:      /* but they will change */
                   8003:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8004:        sumnewm[cptcod]=0.;
                   8005:        sumnewmr[cptcod]=0.;
                   8006:        for (i=1; i<=nlstate;i++){
                   8007:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8008:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8009:        }
                   8010:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8011:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8012:           agemaxgoodr[cptcod]=age;  /* age min */
                   8013:           for (i=1; i<=nlstate;i++)
                   8014:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8015:         }else{ /* bad we change the value with the values of good ages */
                   8016:           for (i=1; i<=nlstate;i++){
                   8017:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8018:           } /* i */
                   8019:         } /* end bad */
                   8020:        }else{
                   8021:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8022:           agemaxgood[cptcod]=age;
                   8023:         }else{ /* bad we change the value with the values of good ages */
                   8024:           for (i=1; i<=nlstate;i++){
                   8025:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8026:           } /* i */
                   8027:         } /* end bad */
                   8028:        }/* end else */
                   8029:        sum=0.;sumr=0.;
                   8030:        for (i=1; i<=nlstate;i++){
                   8031:         sum+=mobaverage[(int)age][i][cptcod];
                   8032:         sumr+=probs[(int)age][i][cptcod];
                   8033:        }
                   8034:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8035:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8036:        } /* end bad */
                   8037:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8038:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8039:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8040:        } /* end bad */
                   8041:      }/* age */
1.266     brouard  8042: 
                   8043:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8044:        sumnewm[cptcod]=0.;
1.266     brouard  8045:        sumnewmr[cptcod]=0.;
1.222     brouard  8046:        for (i=1; i<=nlstate;i++){
                   8047:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8048:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8049:        } 
                   8050:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8051:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8052:           agemingoodr[cptcod]=age;
                   8053:           for (i=1; i<=nlstate;i++)
                   8054:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8055:         }else{ /* bad we change the value with the values of good ages */
                   8056:           for (i=1; i<=nlstate;i++){
                   8057:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8058:           } /* i */
                   8059:         } /* end bad */
                   8060:        }else{
                   8061:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8062:           agemingood[cptcod]=age;
                   8063:         }else{ /* bad */
                   8064:           for (i=1; i<=nlstate;i++){
                   8065:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8066:           } /* i */
                   8067:         } /* end bad */
                   8068:        }/* end else */
                   8069:        sum=0.;sumr=0.;
                   8070:        for (i=1; i<=nlstate;i++){
                   8071:         sum+=mobaverage[(int)age][i][cptcod];
                   8072:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8073:        }
1.266     brouard  8074:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8075:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8076:        } /* end bad */
                   8077:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8078:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8079:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8080:        } /* end bad */
                   8081:      }/* age */
1.266     brouard  8082: 
1.222     brouard  8083:                
                   8084:      for (age=bage; age<=fage; age++){
1.235     brouard  8085:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8086:        sumnewp[cptcod]=0.;
                   8087:        sumnewm[cptcod]=0.;
                   8088:        for (i=1; i<=nlstate;i++){
                   8089:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8090:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8091:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8092:        }
                   8093:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8094:      }
                   8095:      /* printf("\n"); */
                   8096:      /* } */
1.266     brouard  8097: 
1.222     brouard  8098:      /* brutal averaging */
1.266     brouard  8099:      /* for (i=1; i<=nlstate;i++){ */
                   8100:      /*   for (age=1; age<=bage; age++){ */
                   8101:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8102:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8103:      /*   }     */
                   8104:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8105:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8106:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8107:      /*   } */
                   8108:      /* } /\* end i status *\/ */
                   8109:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8110:      /*   for (age=1; age<=AGESUP; age++){ */
                   8111:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8112:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8113:      /*   } */
                   8114:      /* } */
1.222     brouard  8115:    }/* end cptcod */
1.266     brouard  8116:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8117:    free_vector(agemaxgood,1, ncovcombmax);
                   8118:    free_vector(agemingood,1, ncovcombmax);
                   8119:    free_vector(agemingoodr,1, ncovcombmax);
                   8120:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8121:    free_vector(sumnewm,1, ncovcombmax);
                   8122:    free_vector(sumnewp,1, ncovcombmax);
                   8123:    return 0;
                   8124:  }/* End movingaverage */
1.218     brouard  8125:  
1.126     brouard  8126: 
                   8127: /************** Forecasting ******************/
1.269     brouard  8128:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8129:   /* proj1, year, month, day of starting projection 
                   8130:      agemin, agemax range of age
                   8131:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8132:      anproj2 year of en of projection (same day and month as proj1).
                   8133:   */
1.267     brouard  8134:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8135:   double agec; /* generic age */
                   8136:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8137:   double *popeffectif,*popcount;
                   8138:   double ***p3mat;
1.218     brouard  8139:   /* double ***mobaverage; */
1.126     brouard  8140:   char fileresf[FILENAMELENGTH];
                   8141: 
                   8142:   agelim=AGESUP;
1.211     brouard  8143:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8144:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8145:      We still use firstpass and lastpass as another selection.
                   8146:   */
1.214     brouard  8147:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8148:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8149:  
1.201     brouard  8150:   strcpy(fileresf,"F_"); 
                   8151:   strcat(fileresf,fileresu);
1.126     brouard  8152:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8153:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8154:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8155:   }
1.235     brouard  8156:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8157:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8158: 
1.225     brouard  8159:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8160: 
                   8161: 
                   8162:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8163:   if (stepm<=12) stepsize=1;
                   8164:   if(estepm < stepm){
                   8165:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8166:   }
1.270     brouard  8167:   else{
                   8168:     hstepm=estepm;   
                   8169:   }
                   8170:   if(estepm > stepm){ /* Yes every two year */
                   8171:     stepsize=2;
                   8172:   }
1.126     brouard  8173: 
                   8174:   hstepm=hstepm/stepm; 
                   8175:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8176:                                fractional in yp1 */
                   8177:   anprojmean=yp;
                   8178:   yp2=modf((yp1*12),&yp);
                   8179:   mprojmean=yp;
                   8180:   yp1=modf((yp2*30.5),&yp);
                   8181:   jprojmean=yp;
                   8182:   if(jprojmean==0) jprojmean=1;
                   8183:   if(mprojmean==0) jprojmean=1;
                   8184: 
1.227     brouard  8185:   i1=pow(2,cptcoveff);
1.126     brouard  8186:   if (cptcovn < 1){i1=1;}
                   8187:   
                   8188:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8189:   
                   8190:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8191:   
1.126     brouard  8192: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8193:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8194:   for(k=1; k<=i1;k++){
1.253     brouard  8195:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8196:       continue;
1.227     brouard  8197:     if(invalidvarcomb[k]){
                   8198:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8199:       continue;
                   8200:     }
                   8201:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8202:     for(j=1;j<=cptcoveff;j++) {
                   8203:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8204:     }
1.235     brouard  8205:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8206:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8207:     }
1.227     brouard  8208:     fprintf(ficresf," yearproj age");
                   8209:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8210:       for(i=1; i<=nlstate;i++)               
                   8211:        fprintf(ficresf," p%d%d",i,j);
                   8212:       fprintf(ficresf," wp.%d",j);
                   8213:     }
                   8214:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8215:       fprintf(ficresf,"\n");
                   8216:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8217:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8218:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8219:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8220:        nhstepm = nhstepm/hstepm; 
                   8221:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8222:        oldm=oldms;savm=savms;
1.268     brouard  8223:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8224:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8225:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8226:        for (h=0; h<=nhstepm; h++){
                   8227:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8228:            break;
                   8229:          }
                   8230:        }
                   8231:        fprintf(ficresf,"\n");
                   8232:        for(j=1;j<=cptcoveff;j++) 
                   8233:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8234:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8235:        
                   8236:        for(j=1; j<=nlstate+ndeath;j++) {
                   8237:          ppij=0.;
                   8238:          for(i=1; i<=nlstate;i++) {
                   8239:            /* if (mobilav>=1)  */
1.269     brouard  8240:            ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
1.268     brouard  8241:            /* else { */ /* even if mobilav==-1 we use mobaverage */
                   8242:            /*  ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8243:            /* } */
                   8244:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8245:          } /* end i */
                   8246:          fprintf(ficresf," %.3f", ppij);
                   8247:        }/* end j */
1.227     brouard  8248:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8249:       } /* end agec */
1.266     brouard  8250:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8251:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8252:     } /* end yearp */
                   8253:   } /* end  k */
1.219     brouard  8254:        
1.126     brouard  8255:   fclose(ficresf);
1.215     brouard  8256:   printf("End of Computing forecasting \n");
                   8257:   fprintf(ficlog,"End of Computing forecasting\n");
                   8258: 
1.126     brouard  8259: }
                   8260: 
1.269     brouard  8261: /************** Back Forecasting ******************/
                   8262:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8263:   /* back1, year, month, day of starting backection
                   8264:      agemin, agemax range of age
                   8265:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8266:      anback2 year of end of backprojection (same day and month as back1).
                   8267:      prevacurrent and prev are prevalences.
1.267     brouard  8268:   */
                   8269:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8270:   double agec; /* generic age */
1.268     brouard  8271:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8272:   double *popeffectif,*popcount;
                   8273:   double ***p3mat;
                   8274:   /* double ***mobaverage; */
                   8275:   char fileresfb[FILENAMELENGTH];
                   8276:  
1.268     brouard  8277:   agelim=AGEINF;
1.267     brouard  8278:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8279:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8280:      We still use firstpass and lastpass as another selection.
                   8281:   */
                   8282:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8283:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8284: 
                   8285:   /*Do we need to compute prevalence again?*/
                   8286: 
                   8287:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8288:   
                   8289:   strcpy(fileresfb,"FB_");
                   8290:   strcat(fileresfb,fileresu);
                   8291:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8292:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8293:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8294:   }
                   8295:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8296:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8297:   
                   8298:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8299:   
                   8300:    
                   8301:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8302:   if (stepm<=12) stepsize=1;
                   8303:   if(estepm < stepm){
                   8304:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8305:   }
1.270     brouard  8306:   else{
                   8307:     hstepm=estepm;   
                   8308:   }
                   8309:   if(estepm >= stepm){ /* Yes every two year */
                   8310:     stepsize=2;
                   8311:   }
1.267     brouard  8312:   
                   8313:   hstepm=hstepm/stepm;
                   8314:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8315:                                fractional in yp1 */
                   8316:   anprojmean=yp;
                   8317:   yp2=modf((yp1*12),&yp);
                   8318:   mprojmean=yp;
                   8319:   yp1=modf((yp2*30.5),&yp);
                   8320:   jprojmean=yp;
                   8321:   if(jprojmean==0) jprojmean=1;
                   8322:   if(mprojmean==0) jprojmean=1;
                   8323:   
                   8324:   i1=pow(2,cptcoveff);
                   8325:   if (cptcovn < 1){i1=1;}
                   8326:   
                   8327:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8328:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8329:   
                   8330:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8331:   
                   8332:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8333:   for(k=1; k<=i1;k++){
                   8334:     if(i1 != 1 && TKresult[nres]!= k)
                   8335:       continue;
                   8336:     if(invalidvarcomb[k]){
                   8337:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8338:       continue;
                   8339:     }
1.268     brouard  8340:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8341:     for(j=1;j<=cptcoveff;j++) {
                   8342:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8343:     }
                   8344:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8345:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8346:     }
                   8347:     fprintf(ficresfb," yearbproj age");
                   8348:     for(j=1; j<=nlstate+ndeath;j++){
                   8349:       for(i=1; i<=nlstate;i++)
1.268     brouard  8350:        fprintf(ficresfb," b%d%d",i,j);
                   8351:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8352:     }
                   8353:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8354:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8355:       fprintf(ficresfb,"\n");
                   8356:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273   ! brouard  8357:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8358:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8359:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8360:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8361:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8362:        nhstepm = nhstepm/hstepm;
                   8363:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8364:        oldm=oldms;savm=savms;
1.268     brouard  8365:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8366:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8367:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8368:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8369:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8370:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8371:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8372:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8373:            break;
                   8374:          }
                   8375:        }
                   8376:        fprintf(ficresfb,"\n");
                   8377:        for(j=1;j<=cptcoveff;j++)
                   8378:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8379:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8380:        for(i=1; i<=nlstate+ndeath;i++) {
                   8381:          ppij=0.;ppi=0.;
                   8382:          for(j=1; j<=nlstate;j++) {
                   8383:            /* if (mobilav==1) */
1.269     brouard  8384:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8385:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8386:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8387:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8388:              /* else { */
                   8389:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8390:              /* } */
1.268     brouard  8391:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8392:          } /* end j */
                   8393:          if(ppi <0.99){
                   8394:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8395:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8396:          }
                   8397:          fprintf(ficresfb," %.3f", ppij);
                   8398:        }/* end j */
1.267     brouard  8399:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8400:       } /* end agec */
                   8401:     } /* end yearp */
                   8402:   } /* end k */
1.217     brouard  8403:   
1.267     brouard  8404:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8405:   
1.267     brouard  8406:   fclose(ficresfb);
                   8407:   printf("End of Computing Back forecasting \n");
                   8408:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8409:        
1.267     brouard  8410: }
1.217     brouard  8411: 
1.269     brouard  8412: /* Variance of prevalence limit: varprlim */
                   8413:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8414:     /*------- Variance of period (stable) prevalence------*/   
                   8415:  
                   8416:    char fileresvpl[FILENAMELENGTH];  
                   8417:    FILE *ficresvpl;
                   8418:    double **oldm, **savm;
                   8419:    double **varpl; /* Variances of prevalence limits by age */   
                   8420:    int i1, k, nres, j ;
                   8421:    
                   8422:     strcpy(fileresvpl,"VPL_");
                   8423:     strcat(fileresvpl,fileresu);
                   8424:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8425:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8426:       exit(0);
                   8427:     }
                   8428:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8429:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8430:     
                   8431:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8432:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8433:     
                   8434:     i1=pow(2,cptcoveff);
                   8435:     if (cptcovn < 1){i1=1;}
                   8436: 
                   8437:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8438:     for(k=1; k<=i1;k++){
                   8439:       if(i1 != 1 && TKresult[nres]!= k)
                   8440:        continue;
                   8441:       fprintf(ficresvpl,"\n#****** ");
                   8442:       printf("\n#****** ");
                   8443:       fprintf(ficlog,"\n#****** ");
                   8444:       for(j=1;j<=cptcoveff;j++) {
                   8445:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8446:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8447:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8448:       }
                   8449:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8450:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8451:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8452:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8453:       }        
                   8454:       fprintf(ficresvpl,"******\n");
                   8455:       printf("******\n");
                   8456:       fprintf(ficlog,"******\n");
                   8457:       
                   8458:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8459:       oldm=oldms;savm=savms;
                   8460:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8461:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8462:       /*}*/
                   8463:     }
                   8464:     
                   8465:     fclose(ficresvpl);
                   8466:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8467:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8468: 
                   8469:  }
                   8470: /* Variance of back prevalence: varbprlim */
                   8471:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8472:       /*------- Variance of back (stable) prevalence------*/
                   8473: 
                   8474:    char fileresvbl[FILENAMELENGTH];  
                   8475:    FILE  *ficresvbl;
                   8476: 
                   8477:    double **oldm, **savm;
                   8478:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8479:    int i1, k, nres, j ;
                   8480: 
                   8481:    strcpy(fileresvbl,"VBL_");
                   8482:    strcat(fileresvbl,fileresu);
                   8483:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8484:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8485:      exit(0);
                   8486:    }
                   8487:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8488:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8489:    
                   8490:    
                   8491:    i1=pow(2,cptcoveff);
                   8492:    if (cptcovn < 1){i1=1;}
                   8493:    
                   8494:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8495:      for(k=1; k<=i1;k++){
                   8496:        if(i1 != 1 && TKresult[nres]!= k)
                   8497:         continue;
                   8498:        fprintf(ficresvbl,"\n#****** ");
                   8499:        printf("\n#****** ");
                   8500:        fprintf(ficlog,"\n#****** ");
                   8501:        for(j=1;j<=cptcoveff;j++) {
                   8502:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8503:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8504:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8505:        }
                   8506:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8507:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8508:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8509:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8510:        }
                   8511:        fprintf(ficresvbl,"******\n");
                   8512:        printf("******\n");
                   8513:        fprintf(ficlog,"******\n");
                   8514:        
                   8515:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8516:        oldm=oldms;savm=savms;
                   8517:        
                   8518:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8519:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8520:        /*}*/
                   8521:      }
                   8522:    
                   8523:    fclose(ficresvbl);
                   8524:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8525:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8526: 
                   8527:  } /* End of varbprlim */
                   8528: 
1.126     brouard  8529: /************** Forecasting *****not tested NB*************/
1.227     brouard  8530: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8531:   
1.227     brouard  8532: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8533: /*   int *popage; */
                   8534: /*   double calagedatem, agelim, kk1, kk2; */
                   8535: /*   double *popeffectif,*popcount; */
                   8536: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8537: /*   /\* double ***mobaverage; *\/ */
                   8538: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8539: 
1.227     brouard  8540: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8541: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8542: /*   agelim=AGESUP; */
                   8543: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8544:   
1.227     brouard  8545: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8546:   
                   8547:   
1.227     brouard  8548: /*   strcpy(filerespop,"POP_");  */
                   8549: /*   strcat(filerespop,fileresu); */
                   8550: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8551: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8552: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8553: /*   } */
                   8554: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8555: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8556: 
1.227     brouard  8557: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8558: 
1.227     brouard  8559: /*   /\* if (mobilav!=0) { *\/ */
                   8560: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8561: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8562: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8563: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8564: /*   /\*   } *\/ */
                   8565: /*   /\* } *\/ */
1.126     brouard  8566: 
1.227     brouard  8567: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8568: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8569:   
1.227     brouard  8570: /*   agelim=AGESUP; */
1.126     brouard  8571:   
1.227     brouard  8572: /*   hstepm=1; */
                   8573: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8574:        
1.227     brouard  8575: /*   if (popforecast==1) { */
                   8576: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8577: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8578: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8579: /*     }  */
                   8580: /*     popage=ivector(0,AGESUP); */
                   8581: /*     popeffectif=vector(0,AGESUP); */
                   8582: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8583:     
1.227     brouard  8584: /*     i=1;    */
                   8585: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8586:     
1.227     brouard  8587: /*     imx=i; */
                   8588: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8589: /*   } */
1.218     brouard  8590:   
1.227     brouard  8591: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8592: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8593: /*       k=k+1; */
                   8594: /*       fprintf(ficrespop,"\n#******"); */
                   8595: /*       for(j=1;j<=cptcoveff;j++) { */
                   8596: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8597: /*       } */
                   8598: /*       fprintf(ficrespop,"******\n"); */
                   8599: /*       fprintf(ficrespop,"# Age"); */
                   8600: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8601: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8602:       
1.227     brouard  8603: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8604: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8605:        
1.227     brouard  8606: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8607: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8608: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8609:          
1.227     brouard  8610: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8611: /*       oldm=oldms;savm=savms; */
                   8612: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8613:          
1.227     brouard  8614: /*       for (h=0; h<=nhstepm; h++){ */
                   8615: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8616: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8617: /*         }  */
                   8618: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8619: /*           kk1=0.;kk2=0; */
                   8620: /*           for(i=1; i<=nlstate;i++) {               */
                   8621: /*             if (mobilav==1)  */
                   8622: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8623: /*             else { */
                   8624: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8625: /*             } */
                   8626: /*           } */
                   8627: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8628: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8629: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8630: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8631: /*           } */
                   8632: /*         } */
                   8633: /*         for(i=1; i<=nlstate;i++){ */
                   8634: /*           kk1=0.; */
                   8635: /*           for(j=1; j<=nlstate;j++){ */
                   8636: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8637: /*           } */
                   8638: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8639: /*         } */
1.218     brouard  8640:            
1.227     brouard  8641: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8642: /*           for(j=1; j<=nlstate;j++)  */
                   8643: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8644: /*       } */
                   8645: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8646: /*     } */
                   8647: /*       } */
1.218     brouard  8648:       
1.227     brouard  8649: /*       /\******\/ */
1.218     brouard  8650:       
1.227     brouard  8651: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8652: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8653: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8654: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8655: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8656:          
1.227     brouard  8657: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8658: /*       oldm=oldms;savm=savms; */
                   8659: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8660: /*       for (h=0; h<=nhstepm; h++){ */
                   8661: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8662: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8663: /*         }  */
                   8664: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8665: /*           kk1=0.;kk2=0; */
                   8666: /*           for(i=1; i<=nlstate;i++) {               */
                   8667: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8668: /*           } */
                   8669: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8670: /*         } */
                   8671: /*       } */
                   8672: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8673: /*     } */
                   8674: /*       } */
                   8675: /*     }  */
                   8676: /*   } */
1.218     brouard  8677:   
1.227     brouard  8678: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8679:   
1.227     brouard  8680: /*   if (popforecast==1) { */
                   8681: /*     free_ivector(popage,0,AGESUP); */
                   8682: /*     free_vector(popeffectif,0,AGESUP); */
                   8683: /*     free_vector(popcount,0,AGESUP); */
                   8684: /*   } */
                   8685: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8686: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8687: /*   fclose(ficrespop); */
                   8688: /* } /\* End of popforecast *\/ */
1.218     brouard  8689:  
1.126     brouard  8690: int fileappend(FILE *fichier, char *optionfich)
                   8691: {
                   8692:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8693:     printf("Problem with file: %s\n", optionfich);
                   8694:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8695:     return (0);
                   8696:   }
                   8697:   fflush(fichier);
                   8698:   return (1);
                   8699: }
                   8700: 
                   8701: 
                   8702: /**************** function prwizard **********************/
                   8703: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8704: {
                   8705: 
                   8706:   /* Wizard to print covariance matrix template */
                   8707: 
1.164     brouard  8708:   char ca[32], cb[32];
                   8709:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8710:   int numlinepar;
                   8711: 
                   8712:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8713:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8714:   for(i=1; i <=nlstate; i++){
                   8715:     jj=0;
                   8716:     for(j=1; j <=nlstate+ndeath; j++){
                   8717:       if(j==i) continue;
                   8718:       jj++;
                   8719:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8720:       printf("%1d%1d",i,j);
                   8721:       fprintf(ficparo,"%1d%1d",i,j);
                   8722:       for(k=1; k<=ncovmodel;k++){
                   8723:        /*        printf(" %lf",param[i][j][k]); */
                   8724:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8725:        printf(" 0.");
                   8726:        fprintf(ficparo," 0.");
                   8727:       }
                   8728:       printf("\n");
                   8729:       fprintf(ficparo,"\n");
                   8730:     }
                   8731:   }
                   8732:   printf("# Scales (for hessian or gradient estimation)\n");
                   8733:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8734:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8735:   for(i=1; i <=nlstate; i++){
                   8736:     jj=0;
                   8737:     for(j=1; j <=nlstate+ndeath; j++){
                   8738:       if(j==i) continue;
                   8739:       jj++;
                   8740:       fprintf(ficparo,"%1d%1d",i,j);
                   8741:       printf("%1d%1d",i,j);
                   8742:       fflush(stdout);
                   8743:       for(k=1; k<=ncovmodel;k++){
                   8744:        /*      printf(" %le",delti3[i][j][k]); */
                   8745:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8746:        printf(" 0.");
                   8747:        fprintf(ficparo," 0.");
                   8748:       }
                   8749:       numlinepar++;
                   8750:       printf("\n");
                   8751:       fprintf(ficparo,"\n");
                   8752:     }
                   8753:   }
                   8754:   printf("# Covariance matrix\n");
                   8755: /* # 121 Var(a12)\n\ */
                   8756: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8757: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8758: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8759: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8760: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8761: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8762: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8763:   fflush(stdout);
                   8764:   fprintf(ficparo,"# Covariance matrix\n");
                   8765:   /* # 121 Var(a12)\n\ */
                   8766:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8767:   /* #   ...\n\ */
                   8768:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8769:   
                   8770:   for(itimes=1;itimes<=2;itimes++){
                   8771:     jj=0;
                   8772:     for(i=1; i <=nlstate; i++){
                   8773:       for(j=1; j <=nlstate+ndeath; j++){
                   8774:        if(j==i) continue;
                   8775:        for(k=1; k<=ncovmodel;k++){
                   8776:          jj++;
                   8777:          ca[0]= k+'a'-1;ca[1]='\0';
                   8778:          if(itimes==1){
                   8779:            printf("#%1d%1d%d",i,j,k);
                   8780:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8781:          }else{
                   8782:            printf("%1d%1d%d",i,j,k);
                   8783:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8784:            /*  printf(" %.5le",matcov[i][j]); */
                   8785:          }
                   8786:          ll=0;
                   8787:          for(li=1;li <=nlstate; li++){
                   8788:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8789:              if(lj==li) continue;
                   8790:              for(lk=1;lk<=ncovmodel;lk++){
                   8791:                ll++;
                   8792:                if(ll<=jj){
                   8793:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8794:                  if(ll<jj){
                   8795:                    if(itimes==1){
                   8796:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8797:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8798:                    }else{
                   8799:                      printf(" 0.");
                   8800:                      fprintf(ficparo," 0.");
                   8801:                    }
                   8802:                  }else{
                   8803:                    if(itimes==1){
                   8804:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8805:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8806:                    }else{
                   8807:                      printf(" 0.");
                   8808:                      fprintf(ficparo," 0.");
                   8809:                    }
                   8810:                  }
                   8811:                }
                   8812:              } /* end lk */
                   8813:            } /* end lj */
                   8814:          } /* end li */
                   8815:          printf("\n");
                   8816:          fprintf(ficparo,"\n");
                   8817:          numlinepar++;
                   8818:        } /* end k*/
                   8819:       } /*end j */
                   8820:     } /* end i */
                   8821:   } /* end itimes */
                   8822: 
                   8823: } /* end of prwizard */
                   8824: /******************* Gompertz Likelihood ******************************/
                   8825: double gompertz(double x[])
                   8826: { 
                   8827:   double A,B,L=0.0,sump=0.,num=0.;
                   8828:   int i,n=0; /* n is the size of the sample */
                   8829: 
1.220     brouard  8830:   for (i=1;i<=imx ; i++) {
1.126     brouard  8831:     sump=sump+weight[i];
                   8832:     /*    sump=sump+1;*/
                   8833:     num=num+1;
                   8834:   }
                   8835:  
                   8836:  
                   8837:   /* for (i=0; i<=imx; i++) 
                   8838:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8839: 
                   8840:   for (i=1;i<=imx ; i++)
                   8841:     {
                   8842:       if (cens[i] == 1 && wav[i]>1)
                   8843:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8844:       
                   8845:       if (cens[i] == 0 && wav[i]>1)
                   8846:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8847:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8848:       
                   8849:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8850:       if (wav[i] > 1 ) { /* ??? */
                   8851:        L=L+A*weight[i];
                   8852:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8853:       }
                   8854:     }
                   8855: 
                   8856:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8857:  
                   8858:   return -2*L*num/sump;
                   8859: }
                   8860: 
1.136     brouard  8861: #ifdef GSL
                   8862: /******************* Gompertz_f Likelihood ******************************/
                   8863: double gompertz_f(const gsl_vector *v, void *params)
                   8864: { 
                   8865:   double A,B,LL=0.0,sump=0.,num=0.;
                   8866:   double *x= (double *) v->data;
                   8867:   int i,n=0; /* n is the size of the sample */
                   8868: 
                   8869:   for (i=0;i<=imx-1 ; i++) {
                   8870:     sump=sump+weight[i];
                   8871:     /*    sump=sump+1;*/
                   8872:     num=num+1;
                   8873:   }
                   8874:  
                   8875:  
                   8876:   /* for (i=0; i<=imx; i++) 
                   8877:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8878:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   8879:   for (i=1;i<=imx ; i++)
                   8880:     {
                   8881:       if (cens[i] == 1 && wav[i]>1)
                   8882:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   8883:       
                   8884:       if (cens[i] == 0 && wav[i]>1)
                   8885:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   8886:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   8887:       
                   8888:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8889:       if (wav[i] > 1 ) { /* ??? */
                   8890:        LL=LL+A*weight[i];
                   8891:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8892:       }
                   8893:     }
                   8894: 
                   8895:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8896:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   8897:  
                   8898:   return -2*LL*num/sump;
                   8899: }
                   8900: #endif
                   8901: 
1.126     brouard  8902: /******************* Printing html file ***********/
1.201     brouard  8903: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  8904:                  int lastpass, int stepm, int weightopt, char model[],\
                   8905:                  int imx,  double p[],double **matcov,double agemortsup){
                   8906:   int i,k;
                   8907: 
                   8908:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   8909:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   8910:   for (i=1;i<=2;i++) 
                   8911:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  8912:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  8913:   fprintf(fichtm,"</ul>");
                   8914: 
                   8915: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   8916: 
                   8917:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   8918: 
                   8919:  for (k=agegomp;k<(agemortsup-2);k++) 
                   8920:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   8921: 
                   8922:  
                   8923:   fflush(fichtm);
                   8924: }
                   8925: 
                   8926: /******************* Gnuplot file **************/
1.201     brouard  8927: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  8928: 
                   8929:   char dirfileres[132],optfileres[132];
1.164     brouard  8930: 
1.126     brouard  8931:   int ng;
                   8932: 
                   8933: 
                   8934:   /*#ifdef windows */
                   8935:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   8936:     /*#endif */
                   8937: 
                   8938: 
                   8939:   strcpy(dirfileres,optionfilefiname);
                   8940:   strcpy(optfileres,"vpl");
1.199     brouard  8941:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  8942:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  8943:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  8944:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  8945:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   8946: 
                   8947: } 
                   8948: 
1.136     brouard  8949: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   8950: {
1.126     brouard  8951: 
1.136     brouard  8952:   /*-------- data file ----------*/
                   8953:   FILE *fic;
                   8954:   char dummy[]="                         ";
1.240     brouard  8955:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  8956:   int lstra;
1.136     brouard  8957:   int linei, month, year,iout;
                   8958:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  8959:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  8960:   char *stratrunc;
1.223     brouard  8961: 
1.240     brouard  8962:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   8963:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  8964: 
1.240     brouard  8965:   for(v=1; v <=ncovcol;v++){
                   8966:     DummyV[v]=0;
                   8967:     FixedV[v]=0;
                   8968:   }
                   8969:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   8970:     DummyV[v]=1;
                   8971:     FixedV[v]=0;
                   8972:   }
                   8973:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   8974:     DummyV[v]=0;
                   8975:     FixedV[v]=1;
                   8976:   }
                   8977:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8978:     DummyV[v]=1;
                   8979:     FixedV[v]=1;
                   8980:   }
                   8981:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   8982:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8983:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   8984:   }
1.126     brouard  8985: 
1.136     brouard  8986:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  8987:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   8988:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  8989:   }
1.126     brouard  8990: 
1.136     brouard  8991:   i=1;
                   8992:   linei=0;
                   8993:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   8994:     linei=linei+1;
                   8995:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   8996:       if(line[j] == '\t')
                   8997:        line[j] = ' ';
                   8998:     }
                   8999:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9000:       ;
                   9001:     };
                   9002:     line[j+1]=0;  /* Trims blanks at end of line */
                   9003:     if(line[0]=='#'){
                   9004:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9005:       printf("Comment line\n%s\n",line);
                   9006:       continue;
                   9007:     }
                   9008:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9009:     strcpy(line, linetmp);
1.223     brouard  9010:     
                   9011:     /* Loops on waves */
                   9012:     for (j=maxwav;j>=1;j--){
                   9013:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9014:        cutv(stra, strb, line, ' '); 
                   9015:        if(strb[0]=='.') { /* Missing value */
                   9016:          lval=-1;
                   9017:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9018:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9019:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9020:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9021:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9022:            return 1;
                   9023:          }
                   9024:        }else{
                   9025:          errno=0;
                   9026:          /* what_kind_of_number(strb); */
                   9027:          dval=strtod(strb,&endptr); 
                   9028:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9029:          /* if(strb != endptr && *endptr == '\0') */
                   9030:          /*    dval=dlval; */
                   9031:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9032:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9033:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9034:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9035:            return 1;
                   9036:          }
                   9037:          cotqvar[j][iv][i]=dval; 
                   9038:          cotvar[j][ntv+iv][i]=dval; 
                   9039:        }
                   9040:        strcpy(line,stra);
1.223     brouard  9041:       }/* end loop ntqv */
1.225     brouard  9042:       
1.223     brouard  9043:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9044:        cutv(stra, strb, line, ' '); 
                   9045:        if(strb[0]=='.') { /* Missing value */
                   9046:          lval=-1;
                   9047:        }else{
                   9048:          errno=0;
                   9049:          lval=strtol(strb,&endptr,10); 
                   9050:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9051:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9052:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9053:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9054:            return 1;
                   9055:          }
                   9056:        }
                   9057:        if(lval <-1 || lval >1){
                   9058:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9059:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9060:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9061:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9062:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9063:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9064:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9065:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9066:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9067:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9068:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9069:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9070:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9071:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9072:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9073:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9074:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9075:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9076:          return 1;
                   9077:        }
                   9078:        cotvar[j][iv][i]=(double)(lval);
                   9079:        strcpy(line,stra);
1.223     brouard  9080:       }/* end loop ntv */
1.225     brouard  9081:       
1.223     brouard  9082:       /* Statuses  at wave */
1.137     brouard  9083:       cutv(stra, strb, line, ' '); 
1.223     brouard  9084:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9085:        lval=-1;
1.136     brouard  9086:       }else{
1.238     brouard  9087:        errno=0;
                   9088:        lval=strtol(strb,&endptr,10); 
                   9089:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9090:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9091:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9092:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9093:          return 1;
                   9094:        }
1.136     brouard  9095:       }
1.225     brouard  9096:       
1.136     brouard  9097:       s[j][i]=lval;
1.225     brouard  9098:       
1.223     brouard  9099:       /* Date of Interview */
1.136     brouard  9100:       strcpy(line,stra);
                   9101:       cutv(stra, strb,line,' ');
1.169     brouard  9102:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9103:       }
1.169     brouard  9104:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9105:        month=99;
                   9106:        year=9999;
1.136     brouard  9107:       }else{
1.225     brouard  9108:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9109:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9110:        return 1;
1.136     brouard  9111:       }
                   9112:       anint[j][i]= (double) year; 
                   9113:       mint[j][i]= (double)month; 
                   9114:       strcpy(line,stra);
1.223     brouard  9115:     } /* End loop on waves */
1.225     brouard  9116:     
1.223     brouard  9117:     /* Date of death */
1.136     brouard  9118:     cutv(stra, strb,line,' '); 
1.169     brouard  9119:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9120:     }
1.169     brouard  9121:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9122:       month=99;
                   9123:       year=9999;
                   9124:     }else{
1.141     brouard  9125:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9126:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9127:       return 1;
1.136     brouard  9128:     }
                   9129:     andc[i]=(double) year; 
                   9130:     moisdc[i]=(double) month; 
                   9131:     strcpy(line,stra);
                   9132:     
1.223     brouard  9133:     /* Date of birth */
1.136     brouard  9134:     cutv(stra, strb,line,' '); 
1.169     brouard  9135:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9136:     }
1.169     brouard  9137:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9138:       month=99;
                   9139:       year=9999;
                   9140:     }else{
1.141     brouard  9141:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9142:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9143:       return 1;
1.136     brouard  9144:     }
                   9145:     if (year==9999) {
1.141     brouard  9146:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9147:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9148:       return 1;
                   9149:       
1.136     brouard  9150:     }
                   9151:     annais[i]=(double)(year);
                   9152:     moisnais[i]=(double)(month); 
                   9153:     strcpy(line,stra);
1.225     brouard  9154:     
1.223     brouard  9155:     /* Sample weight */
1.136     brouard  9156:     cutv(stra, strb,line,' '); 
                   9157:     errno=0;
                   9158:     dval=strtod(strb,&endptr); 
                   9159:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9160:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9161:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9162:       fflush(ficlog);
                   9163:       return 1;
                   9164:     }
                   9165:     weight[i]=dval; 
                   9166:     strcpy(line,stra);
1.225     brouard  9167:     
1.223     brouard  9168:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9169:       cutv(stra, strb, line, ' '); 
                   9170:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9171:        lval=-1;
1.223     brouard  9172:       }else{
1.225     brouard  9173:        errno=0;
                   9174:        /* what_kind_of_number(strb); */
                   9175:        dval=strtod(strb,&endptr);
                   9176:        /* if(strb != endptr && *endptr == '\0') */
                   9177:        /*   dval=dlval; */
                   9178:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9179:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9180:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9181:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9182:          return 1;
                   9183:        }
                   9184:        coqvar[iv][i]=dval; 
1.226     brouard  9185:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9186:       }
                   9187:       strcpy(line,stra);
                   9188:     }/* end loop nqv */
1.136     brouard  9189:     
1.223     brouard  9190:     /* Covariate values */
1.136     brouard  9191:     for (j=ncovcol;j>=1;j--){
                   9192:       cutv(stra, strb,line,' '); 
1.223     brouard  9193:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9194:        lval=-1;
1.136     brouard  9195:       }else{
1.225     brouard  9196:        errno=0;
                   9197:        lval=strtol(strb,&endptr,10); 
                   9198:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9199:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9200:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9201:          return 1;
                   9202:        }
1.136     brouard  9203:       }
                   9204:       if(lval <-1 || lval >1){
1.225     brouard  9205:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9206:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9207:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9208:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9209:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9210:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9211:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9212:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9213:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9214:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9215:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9216:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9217:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9218:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9219:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9220:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9221:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9222:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9223:        return 1;
1.136     brouard  9224:       }
                   9225:       covar[j][i]=(double)(lval);
                   9226:       strcpy(line,stra);
                   9227:     }  
                   9228:     lstra=strlen(stra);
1.225     brouard  9229:     
1.136     brouard  9230:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9231:       stratrunc = &(stra[lstra-9]);
                   9232:       num[i]=atol(stratrunc);
                   9233:     }
                   9234:     else
                   9235:       num[i]=atol(stra);
                   9236:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9237:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9238:     
                   9239:     i=i+1;
                   9240:   } /* End loop reading  data */
1.225     brouard  9241:   
1.136     brouard  9242:   *imax=i-1; /* Number of individuals */
                   9243:   fclose(fic);
1.225     brouard  9244:   
1.136     brouard  9245:   return (0);
1.164     brouard  9246:   /* endread: */
1.225     brouard  9247:   printf("Exiting readdata: ");
                   9248:   fclose(fic);
                   9249:   return (1);
1.223     brouard  9250: }
1.126     brouard  9251: 
1.234     brouard  9252: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9253:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9254:   while (*p2 == ' ')
1.234     brouard  9255:     p2++; 
                   9256:   /* while ((*p1++ = *p2++) !=0) */
                   9257:   /*   ; */
                   9258:   /* do */
                   9259:   /*   while (*p2 == ' ') */
                   9260:   /*     p2++; */
                   9261:   /* while (*p1++ == *p2++); */
                   9262:   *stri=p2; 
1.145     brouard  9263: }
                   9264: 
1.235     brouard  9265: int decoderesult ( char resultline[], int nres)
1.230     brouard  9266: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9267: {
1.235     brouard  9268:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9269:   char resultsav[MAXLINE];
1.234     brouard  9270:   int resultmodel[MAXLINE];
                   9271:   int modelresult[MAXLINE];
1.230     brouard  9272:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9273: 
1.234     brouard  9274:   removefirstspace(&resultline);
1.233     brouard  9275:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9276: 
                   9277:   if (strstr(resultline,"v") !=0){
                   9278:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9279:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9280:     return 1;
                   9281:   }
                   9282:   trimbb(resultsav, resultline);
                   9283:   if (strlen(resultsav) >1){
                   9284:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9285:   }
1.253     brouard  9286:   if(j == 0){ /* Resultline but no = */
                   9287:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9288:     return (0);
                   9289:   }
                   9290:     
1.234     brouard  9291:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9292:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9293:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9294:   }
                   9295:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9296:     if(nbocc(resultsav,'=') >1){
                   9297:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9298:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9299:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9300:     }else
                   9301:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9302:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9303:     
1.230     brouard  9304:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9305:     Tvarsel[k]=atoi(strc);
                   9306:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9307:     /* cptcovsel++;     */
                   9308:     if (nbocc(stra,'=') >0)
                   9309:       strcpy(resultsav,stra); /* and analyzes it */
                   9310:   }
1.235     brouard  9311:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9312:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9313:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9314:       match=0;
1.236     brouard  9315:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9316:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9317:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9318:          match=1;
                   9319:          break;
                   9320:        }
                   9321:       }
                   9322:       if(match == 0){
                   9323:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9324:       }
                   9325:     }
                   9326:   }
1.235     brouard  9327:   /* Checking for missing or useless values in comparison of current model needs */
                   9328:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9329:     match=0;
1.235     brouard  9330:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9331:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9332:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9333:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9334:          ++match;
                   9335:        }
                   9336:       }
                   9337:     }
                   9338:     if(match == 0){
                   9339:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9340:     }else if(match > 1){
                   9341:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9342:     }
                   9343:   }
1.235     brouard  9344:       
1.234     brouard  9345:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9346:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9347:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9348:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9349:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9350:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9351:   /*    1 0 0 0 */
                   9352:   /*    2 1 0 0 */
                   9353:   /*    3 0 1 0 */ 
                   9354:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9355:   /*    5 0 0 1 */
                   9356:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9357:   /*    7 0 1 1 */
                   9358:   /*    8 1 1 1 */
1.237     brouard  9359:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9360:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9361:   /* V5*age V5 known which value for nres?  */
                   9362:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9363:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9364:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9365:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9366:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9367:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9368:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9369:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9370:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9371:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9372:       k4++;;
                   9373:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9374:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9375:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9376:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9377:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9378:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9379:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9380:       k4q++;;
                   9381:     }
                   9382:   }
1.234     brouard  9383:   
1.235     brouard  9384:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9385:   return (0);
                   9386: }
1.235     brouard  9387: 
1.230     brouard  9388: int decodemodel( char model[], int lastobs)
                   9389:  /**< This routine decodes the model and returns:
1.224     brouard  9390:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9391:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9392:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9393:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9394:        * - cptcovage number of covariates with age*products =2
                   9395:        * - cptcovs number of simple covariates
                   9396:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9397:        *     which is a new column after the 9 (ncovcol) variables. 
                   9398:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9399:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9400:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9401:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9402:        */
1.136     brouard  9403: {
1.238     brouard  9404:   int i, j, k, ks, v;
1.227     brouard  9405:   int  j1, k1, k2, k3, k4;
1.136     brouard  9406:   char modelsav[80];
1.145     brouard  9407:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9408:   char *strpt;
1.136     brouard  9409: 
1.145     brouard  9410:   /*removespace(model);*/
1.136     brouard  9411:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9412:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9413:     if (strstr(model,"AGE") !=0){
1.192     brouard  9414:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9415:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9416:       return 1;
                   9417:     }
1.141     brouard  9418:     if (strstr(model,"v") !=0){
                   9419:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9420:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9421:       return 1;
                   9422:     }
1.187     brouard  9423:     strcpy(modelsav,model); 
                   9424:     if ((strpt=strstr(model,"age*age")) !=0){
                   9425:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9426:       if(strpt != model){
1.234     brouard  9427:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9428:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9429:  corresponding column of parameters.\n",model);
1.234     brouard  9430:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9431:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9432:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9433:        return 1;
1.225     brouard  9434:       }
1.187     brouard  9435:       nagesqr=1;
                   9436:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9437:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9438:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9439:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9440:       else 
1.234     brouard  9441:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9442:     }else
                   9443:       nagesqr=0;
                   9444:     if (strlen(modelsav) >1){
                   9445:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9446:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9447:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9448:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9449:                     * cst, age and age*age 
                   9450:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9451:       /* including age products which are counted in cptcovage.
                   9452:        * but the covariates which are products must be treated 
                   9453:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9454:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9455:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9456:       
                   9457:       
1.187     brouard  9458:       /*   Design
                   9459:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9460:        *  <          ncovcol=8                >
                   9461:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9462:        *   k=  1    2      3       4     5       6      7        8
                   9463:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9464:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9465:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9466:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9467:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9468:        *  Tage[++cptcovage]=k
                   9469:        *       if products, new covar are created after ncovcol with k1
                   9470:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9471:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9472:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9473:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9474:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9475:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9476:        *  <          ncovcol=8                >
                   9477:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9478:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9479:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9480:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9481:        * p Tprod[1]@2={                         6, 5}
                   9482:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9483:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9484:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9485:        *How to reorganize?
                   9486:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9487:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9488:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9489:        * Struct []
                   9490:        */
1.225     brouard  9491:       
1.187     brouard  9492:       /* This loop fills the array Tvar from the string 'model'.*/
                   9493:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9494:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9495:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9496:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9497:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9498:       /*       k=1 Tvar[1]=2 (from V2) */
                   9499:       /*       k=5 Tvar[5] */
                   9500:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9501:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9502:       /*       } */
1.198     brouard  9503:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9504:       /*
                   9505:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9506:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9507:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9508:       }
1.187     brouard  9509:       cptcovage=0;
                   9510:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9511:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9512:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9513:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9514:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9515:        /*scanf("%d",i);*/
                   9516:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9517:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9518:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9519:            /* covar is not filled and then is empty */
                   9520:            cptcovprod--;
                   9521:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9522:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9523:            Typevar[k]=1;  /* 1 for age product */
                   9524:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9525:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9526:            /*printf("stre=%s ", stre);*/
                   9527:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9528:            cptcovprod--;
                   9529:            cutl(stre,strb,strc,'V');
                   9530:            Tvar[k]=atoi(stre);
                   9531:            Typevar[k]=1;  /* 1 for age product */
                   9532:            cptcovage++;
                   9533:            Tage[cptcovage]=k;
                   9534:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9535:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9536:            cptcovn++;
                   9537:            cptcovprodnoage++;k1++;
                   9538:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9539:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9540:                                                because this model-covariate is a construction we invent a new column
                   9541:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9542:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9543:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9544:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9545:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9546:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9547:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9548:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9549:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9550:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9551:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9552:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9553:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9554:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9555:            for (i=1; i<=lastobs;i++){
                   9556:              /* Computes the new covariate which is a product of
                   9557:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9558:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9559:            }
                   9560:          } /* End age is not in the model */
                   9561:        } /* End if model includes a product */
                   9562:        else { /* no more sum */
                   9563:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9564:          /*  scanf("%d",i);*/
                   9565:          cutl(strd,strc,strb,'V');
                   9566:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9567:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9568:          Tvar[k]=atoi(strd);
                   9569:          Typevar[k]=0;  /* 0 for simple covariates */
                   9570:        }
                   9571:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9572:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9573:                                  scanf("%d",i);*/
1.187     brouard  9574:       } /* end of loop + on total covariates */
                   9575:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9576:   } /* end if strlen(model == 0) */
1.136     brouard  9577:   
                   9578:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9579:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9580:   
1.136     brouard  9581:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9582:      printf("cptcovprod=%d ", cptcovprod);
                   9583:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9584:      scanf("%d ",i);*/
                   9585: 
                   9586: 
1.230     brouard  9587: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9588:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9589: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9590:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9591:    k =           1    2   3     4       5       6      7      8        9
                   9592:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9593:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9594:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9595:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9596:          Tmodelind[combination of covar]=k;
1.225     brouard  9597: */  
                   9598: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9599:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9600:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9601:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9602:   printf("Model=%s\n\
                   9603: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9604: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9605: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9606:   fprintf(ficlog,"Model=%s\n\
                   9607: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9608: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9609: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.240     brouard  9610:   for(k=1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9611:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9612:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9613:       Fixed[k]= 0;
                   9614:       Dummy[k]= 0;
1.225     brouard  9615:       ncoveff++;
1.232     brouard  9616:       ncovf++;
1.234     brouard  9617:       nsd++;
                   9618:       modell[k].maintype= FTYPE;
                   9619:       TvarsD[nsd]=Tvar[k];
                   9620:       TvarsDind[nsd]=k;
                   9621:       TvarF[ncovf]=Tvar[k];
                   9622:       TvarFind[ncovf]=k;
                   9623:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9624:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9625:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9626:       Fixed[k]= 0;
                   9627:       Dummy[k]= 0;
                   9628:       ncoveff++;
                   9629:       ncovf++;
                   9630:       modell[k].maintype= FTYPE;
                   9631:       TvarF[ncovf]=Tvar[k];
                   9632:       TvarFind[ncovf]=k;
1.230     brouard  9633:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9634:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9635:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9636:       Fixed[k]= 0;
                   9637:       Dummy[k]= 1;
1.230     brouard  9638:       nqfveff++;
1.234     brouard  9639:       modell[k].maintype= FTYPE;
                   9640:       modell[k].subtype= FQ;
                   9641:       nsq++;
                   9642:       TvarsQ[nsq]=Tvar[k];
                   9643:       TvarsQind[nsq]=k;
1.232     brouard  9644:       ncovf++;
1.234     brouard  9645:       TvarF[ncovf]=Tvar[k];
                   9646:       TvarFind[ncovf]=k;
1.231     brouard  9647:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9648:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9649:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9650:       Fixed[k]= 1;
                   9651:       Dummy[k]= 0;
1.225     brouard  9652:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9653:       modell[k].maintype= VTYPE;
                   9654:       modell[k].subtype= VD;
                   9655:       nsd++;
                   9656:       TvarsD[nsd]=Tvar[k];
                   9657:       TvarsDind[nsd]=k;
                   9658:       ncovv++; /* Only simple time varying variables */
                   9659:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9660:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9661:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9662:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9663:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9664:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9665:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9666:       Fixed[k]= 1;
                   9667:       Dummy[k]= 1;
                   9668:       nqtveff++;
                   9669:       modell[k].maintype= VTYPE;
                   9670:       modell[k].subtype= VQ;
                   9671:       ncovv++; /* Only simple time varying variables */
                   9672:       nsq++;
                   9673:       TvarsQ[nsq]=Tvar[k];
                   9674:       TvarsQind[nsq]=k;
                   9675:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9676:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9677:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9678:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9679:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9680:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9681:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9682:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9683:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9684:       ncova++;
                   9685:       TvarA[ncova]=Tvar[k];
                   9686:       TvarAind[ncova]=k;
1.231     brouard  9687:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9688:        Fixed[k]= 2;
                   9689:        Dummy[k]= 2;
                   9690:        modell[k].maintype= ATYPE;
                   9691:        modell[k].subtype= APFD;
                   9692:        /* ncoveff++; */
1.227     brouard  9693:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9694:        Fixed[k]= 2;
                   9695:        Dummy[k]= 3;
                   9696:        modell[k].maintype= ATYPE;
                   9697:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9698:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9699:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9700:        Fixed[k]= 3;
                   9701:        Dummy[k]= 2;
                   9702:        modell[k].maintype= ATYPE;
                   9703:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9704:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9705:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9706:        Fixed[k]= 3;
                   9707:        Dummy[k]= 3;
                   9708:        modell[k].maintype= ATYPE;
                   9709:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9710:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9711:       }
                   9712:     }else if (Typevar[k] == 2) {  /* product without age */
                   9713:       k1=Tposprod[k];
                   9714:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9715:        if(Tvard[k1][2] <=ncovcol){
                   9716:          Fixed[k]= 1;
                   9717:          Dummy[k]= 0;
                   9718:          modell[k].maintype= FTYPE;
                   9719:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9720:          ncovf++; /* Fixed variables without age */
                   9721:          TvarF[ncovf]=Tvar[k];
                   9722:          TvarFind[ncovf]=k;
                   9723:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9724:          Fixed[k]= 0;  /* or 2 ?*/
                   9725:          Dummy[k]= 1;
                   9726:          modell[k].maintype= FTYPE;
                   9727:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9728:          ncovf++; /* Varying variables without age */
                   9729:          TvarF[ncovf]=Tvar[k];
                   9730:          TvarFind[ncovf]=k;
                   9731:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9732:          Fixed[k]= 1;
                   9733:          Dummy[k]= 0;
                   9734:          modell[k].maintype= VTYPE;
                   9735:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9736:          ncovv++; /* Varying variables without age */
                   9737:          TvarV[ncovv]=Tvar[k];
                   9738:          TvarVind[ncovv]=k;
                   9739:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9740:          Fixed[k]= 1;
                   9741:          Dummy[k]= 1;
                   9742:          modell[k].maintype= VTYPE;
                   9743:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9744:          ncovv++; /* Varying variables without age */
                   9745:          TvarV[ncovv]=Tvar[k];
                   9746:          TvarVind[ncovv]=k;
                   9747:        }
1.227     brouard  9748:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9749:        if(Tvard[k1][2] <=ncovcol){
                   9750:          Fixed[k]= 0;  /* or 2 ?*/
                   9751:          Dummy[k]= 1;
                   9752:          modell[k].maintype= FTYPE;
                   9753:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9754:          ncovf++; /* Fixed variables without age */
                   9755:          TvarF[ncovf]=Tvar[k];
                   9756:          TvarFind[ncovf]=k;
                   9757:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9758:          Fixed[k]= 1;
                   9759:          Dummy[k]= 1;
                   9760:          modell[k].maintype= VTYPE;
                   9761:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9762:          ncovv++; /* Varying variables without age */
                   9763:          TvarV[ncovv]=Tvar[k];
                   9764:          TvarVind[ncovv]=k;
                   9765:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9766:          Fixed[k]= 1;
                   9767:          Dummy[k]= 1;
                   9768:          modell[k].maintype= VTYPE;
                   9769:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9770:          ncovv++; /* Varying variables without age */
                   9771:          TvarV[ncovv]=Tvar[k];
                   9772:          TvarVind[ncovv]=k;
                   9773:          ncovv++; /* Varying variables without age */
                   9774:          TvarV[ncovv]=Tvar[k];
                   9775:          TvarVind[ncovv]=k;
                   9776:        }
1.227     brouard  9777:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9778:        if(Tvard[k1][2] <=ncovcol){
                   9779:          Fixed[k]= 1;
                   9780:          Dummy[k]= 1;
                   9781:          modell[k].maintype= VTYPE;
                   9782:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9783:          ncovv++; /* Varying variables without age */
                   9784:          TvarV[ncovv]=Tvar[k];
                   9785:          TvarVind[ncovv]=k;
                   9786:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9787:          Fixed[k]= 1;
                   9788:          Dummy[k]= 1;
                   9789:          modell[k].maintype= VTYPE;
                   9790:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9791:          ncovv++; /* Varying variables without age */
                   9792:          TvarV[ncovv]=Tvar[k];
                   9793:          TvarVind[ncovv]=k;
                   9794:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9795:          Fixed[k]= 1;
                   9796:          Dummy[k]= 0;
                   9797:          modell[k].maintype= VTYPE;
                   9798:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9799:          ncovv++; /* Varying variables without age */
                   9800:          TvarV[ncovv]=Tvar[k];
                   9801:          TvarVind[ncovv]=k;
                   9802:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9803:          Fixed[k]= 1;
                   9804:          Dummy[k]= 1;
                   9805:          modell[k].maintype= VTYPE;
                   9806:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9807:          ncovv++; /* Varying variables without age */
                   9808:          TvarV[ncovv]=Tvar[k];
                   9809:          TvarVind[ncovv]=k;
                   9810:        }
1.227     brouard  9811:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9812:        if(Tvard[k1][2] <=ncovcol){
                   9813:          Fixed[k]= 1;
                   9814:          Dummy[k]= 1;
                   9815:          modell[k].maintype= VTYPE;
                   9816:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9817:          ncovv++; /* Varying variables without age */
                   9818:          TvarV[ncovv]=Tvar[k];
                   9819:          TvarVind[ncovv]=k;
                   9820:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9821:          Fixed[k]= 1;
                   9822:          Dummy[k]= 1;
                   9823:          modell[k].maintype= VTYPE;
                   9824:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9825:          ncovv++; /* Varying variables without age */
                   9826:          TvarV[ncovv]=Tvar[k];
                   9827:          TvarVind[ncovv]=k;
                   9828:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9829:          Fixed[k]= 1;
                   9830:          Dummy[k]= 1;
                   9831:          modell[k].maintype= VTYPE;
                   9832:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9833:          ncovv++; /* Varying variables without age */
                   9834:          TvarV[ncovv]=Tvar[k];
                   9835:          TvarVind[ncovv]=k;
                   9836:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9837:          Fixed[k]= 1;
                   9838:          Dummy[k]= 1;
                   9839:          modell[k].maintype= VTYPE;
                   9840:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9841:          ncovv++; /* Varying variables without age */
                   9842:          TvarV[ncovv]=Tvar[k];
                   9843:          TvarVind[ncovv]=k;
                   9844:        }
1.227     brouard  9845:       }else{
1.240     brouard  9846:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9847:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9848:       } /*end k1*/
1.225     brouard  9849:     }else{
1.226     brouard  9850:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9851:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9852:     }
1.227     brouard  9853:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9854:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9855:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9856:   }
                   9857:   /* Searching for doublons in the model */
                   9858:   for(k1=1; k1<= cptcovt;k1++){
                   9859:     for(k2=1; k2 <k1;k2++){
                   9860:       if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){
1.234     brouard  9861:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9862:          if(Tvar[k1]==Tvar[k2]){
                   9863:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9864:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9865:            return(1);
                   9866:          }
                   9867:        }else if (Typevar[k1] ==2){
                   9868:          k3=Tposprod[k1];
                   9869:          k4=Tposprod[k2];
                   9870:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   9871:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   9872:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   9873:            return(1);
                   9874:          }
                   9875:        }
1.227     brouard  9876:       }
                   9877:     }
1.225     brouard  9878:   }
                   9879:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   9880:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  9881:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   9882:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  9883:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  9884:   /*endread:*/
1.225     brouard  9885:   printf("Exiting decodemodel: ");
                   9886:   return (1);
1.136     brouard  9887: }
                   9888: 
1.169     brouard  9889: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  9890: {/* Check ages at death */
1.136     brouard  9891:   int i, m;
1.218     brouard  9892:   int firstone=0;
                   9893:   
1.136     brouard  9894:   for (i=1; i<=imx; i++) {
                   9895:     for(m=2; (m<= maxwav); m++) {
                   9896:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   9897:        anint[m][i]=9999;
1.216     brouard  9898:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   9899:          s[m][i]=-1;
1.136     brouard  9900:       }
                   9901:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  9902:        *nberr = *nberr + 1;
1.218     brouard  9903:        if(firstone == 0){
                   9904:          firstone=1;
1.260     brouard  9905:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  9906:        }
1.262     brouard  9907:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  9908:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  9909:       }
                   9910:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  9911:        (*nberr)++;
1.259     brouard  9912:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  9913:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  9914:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  9915:       }
                   9916:     }
                   9917:   }
                   9918: 
                   9919:   for (i=1; i<=imx; i++)  {
                   9920:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   9921:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  9922:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  9923:        if (s[m][i] >= nlstate+1) {
1.169     brouard  9924:          if(agedc[i]>0){
                   9925:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  9926:              agev[m][i]=agedc[i];
1.214     brouard  9927:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  9928:            }else {
1.136     brouard  9929:              if ((int)andc[i]!=9999){
                   9930:                nbwarn++;
                   9931:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   9932:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   9933:                agev[m][i]=-1;
                   9934:              }
                   9935:            }
1.169     brouard  9936:          } /* agedc > 0 */
1.214     brouard  9937:        } /* end if */
1.136     brouard  9938:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   9939:                                 years but with the precision of a month */
                   9940:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   9941:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   9942:            agev[m][i]=1;
                   9943:          else if(agev[m][i] < *agemin){ 
                   9944:            *agemin=agev[m][i];
                   9945:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   9946:          }
                   9947:          else if(agev[m][i] >*agemax){
                   9948:            *agemax=agev[m][i];
1.156     brouard  9949:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  9950:          }
                   9951:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   9952:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  9953:        } /* en if 9*/
1.136     brouard  9954:        else { /* =9 */
1.214     brouard  9955:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  9956:          agev[m][i]=1;
                   9957:          s[m][i]=-1;
                   9958:        }
                   9959:       }
1.214     brouard  9960:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  9961:        agev[m][i]=1;
1.214     brouard  9962:       else{
                   9963:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9964:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   9965:        agev[m][i]=0;
                   9966:       }
                   9967:     } /* End for lastpass */
                   9968:   }
1.136     brouard  9969:     
                   9970:   for (i=1; i<=imx; i++)  {
                   9971:     for(m=firstpass; (m<=lastpass); m++){
                   9972:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  9973:        (*nberr)++;
1.136     brouard  9974:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9975:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   9976:        return 1;
                   9977:       }
                   9978:     }
                   9979:   }
                   9980: 
                   9981:   /*for (i=1; i<=imx; i++){
                   9982:   for (m=firstpass; (m<lastpass); m++){
                   9983:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   9984: }
                   9985: 
                   9986: }*/
                   9987: 
                   9988: 
1.139     brouard  9989:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   9990:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  9991: 
                   9992:   return (0);
1.164     brouard  9993:  /* endread:*/
1.136     brouard  9994:     printf("Exiting calandcheckages: ");
                   9995:     return (1);
                   9996: }
                   9997: 
1.172     brouard  9998: #if defined(_MSC_VER)
                   9999: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10000: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10001: //#include "stdafx.h"
                   10002: //#include <stdio.h>
                   10003: //#include <tchar.h>
                   10004: //#include <windows.h>
                   10005: //#include <iostream>
                   10006: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10007: 
                   10008: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10009: 
                   10010: BOOL IsWow64()
                   10011: {
                   10012:        BOOL bIsWow64 = FALSE;
                   10013: 
                   10014:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10015:        //  (HANDLE, PBOOL);
                   10016: 
                   10017:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10018: 
                   10019:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10020:        const char funcName[] = "IsWow64Process";
                   10021:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10022:                GetProcAddress(module, funcName);
                   10023: 
                   10024:        if (NULL != fnIsWow64Process)
                   10025:        {
                   10026:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10027:                        &bIsWow64))
                   10028:                        //throw std::exception("Unknown error");
                   10029:                        printf("Unknown error\n");
                   10030:        }
                   10031:        return bIsWow64 != FALSE;
                   10032: }
                   10033: #endif
1.177     brouard  10034: 
1.191     brouard  10035: void syscompilerinfo(int logged)
1.167     brouard  10036:  {
                   10037:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10038:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10039:    /* /GS /W3 /Gy
                   10040:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10041:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10042:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10043:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10044:    */ 
                   10045:    /* 64 bits */
1.185     brouard  10046:    /*
                   10047:      /GS /W3 /Gy
                   10048:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10049:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10050:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10051:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10052:    /* Optimization are useless and O3 is slower than O2 */
                   10053:    /*
                   10054:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10055:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10056:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10057:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10058:    */
1.186     brouard  10059:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10060:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10061:       /PDB:"visual studio
                   10062:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10063:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10064:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10065:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10066:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10067:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10068:       uiAccess='false'"
                   10069:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10070:       /NOLOGO /TLBID:1
                   10071:    */
1.177     brouard  10072: #if defined __INTEL_COMPILER
1.178     brouard  10073: #if defined(__GNUC__)
                   10074:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10075: #endif
1.177     brouard  10076: #elif defined(__GNUC__) 
1.179     brouard  10077: #ifndef  __APPLE__
1.174     brouard  10078: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10079: #endif
1.177     brouard  10080:    struct utsname sysInfo;
1.178     brouard  10081:    int cross = CROSS;
                   10082:    if (cross){
                   10083:           printf("Cross-");
1.191     brouard  10084:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10085:    }
1.174     brouard  10086: #endif
                   10087: 
1.171     brouard  10088: #include <stdint.h>
1.178     brouard  10089: 
1.191     brouard  10090:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10091: #if defined(__clang__)
1.191     brouard  10092:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10093: #endif
                   10094: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10095:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10096: #endif
                   10097: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10098:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10099: #endif
                   10100: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10101:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10102: #endif
                   10103: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10104:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10105: #endif
                   10106: #if defined(_MSC_VER)
1.191     brouard  10107:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10108: #endif
                   10109: #if defined(__PGI)
1.191     brouard  10110:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10111: #endif
                   10112: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10113:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10114: #endif
1.191     brouard  10115:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10116:    
1.167     brouard  10117: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10118: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10119:     // Windows (x64 and x86)
1.191     brouard  10120:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10121: #elif __unix__ // all unices, not all compilers
                   10122:     // Unix
1.191     brouard  10123:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10124: #elif __linux__
                   10125:     // linux
1.191     brouard  10126:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10127: #elif __APPLE__
1.174     brouard  10128:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10129:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10130: #endif
                   10131: 
                   10132: /*  __MINGW32__          */
                   10133: /*  __CYGWIN__  */
                   10134: /* __MINGW64__  */
                   10135: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10136: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10137: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10138: /* _WIN64  // Defined for applications for Win64. */
                   10139: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10140: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10141: 
1.167     brouard  10142: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10143:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10144: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10145:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10146: #else
1.191     brouard  10147:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10148: #endif
                   10149: 
1.169     brouard  10150: #if defined(__GNUC__)
                   10151: # if defined(__GNUC_PATCHLEVEL__)
                   10152: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10153:                             + __GNUC_MINOR__ * 100 \
                   10154:                             + __GNUC_PATCHLEVEL__)
                   10155: # else
                   10156: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10157:                             + __GNUC_MINOR__ * 100)
                   10158: # endif
1.174     brouard  10159:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10160:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10161: 
                   10162:    if (uname(&sysInfo) != -1) {
                   10163:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10164:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10165:    }
                   10166:    else
                   10167:       perror("uname() error");
1.179     brouard  10168:    //#ifndef __INTEL_COMPILER 
                   10169: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10170:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10171:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10172: #endif
1.169     brouard  10173: #endif
1.172     brouard  10174: 
                   10175:    //   void main()
                   10176:    //   {
1.169     brouard  10177: #if defined(_MSC_VER)
1.174     brouard  10178:    if (IsWow64()){
1.191     brouard  10179:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10180:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10181:    }
                   10182:    else{
1.191     brouard  10183:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10184:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10185:    }
1.172     brouard  10186:    //     printf("\nPress Enter to continue...");
                   10187:    //     getchar();
                   10188:    //   }
                   10189: 
1.169     brouard  10190: #endif
                   10191:    
1.167     brouard  10192: 
1.219     brouard  10193: }
1.136     brouard  10194: 
1.219     brouard  10195: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10196:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10197:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10198:   /* double ftolpl = 1.e-10; */
1.180     brouard  10199:   double age, agebase, agelim;
1.203     brouard  10200:   double tot;
1.180     brouard  10201: 
1.202     brouard  10202:   strcpy(filerespl,"PL_");
                   10203:   strcat(filerespl,fileresu);
                   10204:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10205:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10206:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10207:   }
1.227     brouard  10208:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10209:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10210:   pstamp(ficrespl);
1.203     brouard  10211:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10212:   fprintf(ficrespl,"#Age ");
                   10213:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10214:   fprintf(ficrespl,"\n");
1.180     brouard  10215:   
1.219     brouard  10216:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10217: 
1.219     brouard  10218:   agebase=ageminpar;
                   10219:   agelim=agemaxpar;
1.180     brouard  10220: 
1.227     brouard  10221:   /* i1=pow(2,ncoveff); */
1.234     brouard  10222:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10223:   if (cptcovn < 1){i1=1;}
1.180     brouard  10224: 
1.238     brouard  10225:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10226:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10227:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10228:        continue;
1.235     brouard  10229: 
1.238     brouard  10230:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10231:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10232:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10233:       /* k=k+1; */
                   10234:       /* to clean */
                   10235:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10236:       fprintf(ficrespl,"#******");
                   10237:       printf("#******");
                   10238:       fprintf(ficlog,"#******");
                   10239:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10240:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10241:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10242:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10243:       }
                   10244:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10245:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10246:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10247:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10248:       }
                   10249:       fprintf(ficrespl,"******\n");
                   10250:       printf("******\n");
                   10251:       fprintf(ficlog,"******\n");
                   10252:       if(invalidvarcomb[k]){
                   10253:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10254:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10255:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10256:        continue;
                   10257:       }
1.219     brouard  10258: 
1.238     brouard  10259:       fprintf(ficrespl,"#Age ");
                   10260:       for(j=1;j<=cptcoveff;j++) {
                   10261:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10262:       }
                   10263:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10264:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10265:     
1.238     brouard  10266:       for (age=agebase; age<=agelim; age++){
                   10267:        /* for (age=agebase; age<=agebase; age++){ */
                   10268:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10269:        fprintf(ficrespl,"%.0f ",age );
                   10270:        for(j=1;j<=cptcoveff;j++)
                   10271:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10272:        tot=0.;
                   10273:        for(i=1; i<=nlstate;i++){
                   10274:          tot +=  prlim[i][i];
                   10275:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10276:        }
                   10277:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10278:       } /* Age */
                   10279:       /* was end of cptcod */
                   10280:     } /* cptcov */
                   10281:   } /* nres */
1.219     brouard  10282:   return 0;
1.180     brouard  10283: }
                   10284: 
1.218     brouard  10285: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10286:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10287:        
                   10288:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10289:    * at any age between ageminpar and agemaxpar
                   10290:         */
1.235     brouard  10291:   int i, j, k, i1, nres=0 ;
1.217     brouard  10292:   /* double ftolpl = 1.e-10; */
                   10293:   double age, agebase, agelim;
                   10294:   double tot;
1.218     brouard  10295:   /* double ***mobaverage; */
                   10296:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10297: 
                   10298:   strcpy(fileresplb,"PLB_");
                   10299:   strcat(fileresplb,fileresu);
                   10300:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10301:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10302:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10303:   }
                   10304:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10305:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10306:   pstamp(ficresplb);
                   10307:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10308:   fprintf(ficresplb,"#Age ");
                   10309:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10310:   fprintf(ficresplb,"\n");
                   10311:   
1.218     brouard  10312:   
                   10313:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10314:   
                   10315:   agebase=ageminpar;
                   10316:   agelim=agemaxpar;
                   10317:   
                   10318:   
1.227     brouard  10319:   i1=pow(2,cptcoveff);
1.218     brouard  10320:   if (cptcovn < 1){i1=1;}
1.227     brouard  10321:   
1.238     brouard  10322:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10323:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10324:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10325:        continue;
                   10326:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10327:       fprintf(ficresplb,"#******");
                   10328:       printf("#******");
                   10329:       fprintf(ficlog,"#******");
                   10330:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10331:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10332:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10333:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10334:       }
                   10335:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10336:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10337:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10338:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10339:       }
                   10340:       fprintf(ficresplb,"******\n");
                   10341:       printf("******\n");
                   10342:       fprintf(ficlog,"******\n");
                   10343:       if(invalidvarcomb[k]){
                   10344:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10345:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10346:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10347:        continue;
                   10348:       }
1.218     brouard  10349:     
1.238     brouard  10350:       fprintf(ficresplb,"#Age ");
                   10351:       for(j=1;j<=cptcoveff;j++) {
                   10352:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10353:       }
                   10354:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10355:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10356:     
                   10357:     
1.238     brouard  10358:       for (age=agebase; age<=agelim; age++){
                   10359:        /* for (age=agebase; age<=agebase; age++){ */
                   10360:        if(mobilavproj > 0){
                   10361:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10362:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10363:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10364:        }else if (mobilavproj == 0){
                   10365:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10366:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10367:          exit(1);
                   10368:        }else{
                   10369:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10370:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10371:          /* printf("TOTOT\n"); */
                   10372:           /* exit(1); */
1.238     brouard  10373:        }
                   10374:        fprintf(ficresplb,"%.0f ",age );
                   10375:        for(j=1;j<=cptcoveff;j++)
                   10376:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10377:        tot=0.;
                   10378:        for(i=1; i<=nlstate;i++){
                   10379:          tot +=  bprlim[i][i];
                   10380:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10381:        }
                   10382:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10383:       } /* Age */
                   10384:       /* was end of cptcod */
1.255     brouard  10385:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10386:     } /* end of any combination */
                   10387:   } /* end of nres */  
1.218     brouard  10388:   /* hBijx(p, bage, fage); */
                   10389:   /* fclose(ficrespijb); */
                   10390:   
                   10391:   return 0;
1.217     brouard  10392: }
1.218     brouard  10393:  
1.180     brouard  10394: int hPijx(double *p, int bage, int fage){
                   10395:     /*------------- h Pij x at various ages ------------*/
                   10396: 
                   10397:   int stepsize;
                   10398:   int agelim;
                   10399:   int hstepm;
                   10400:   int nhstepm;
1.235     brouard  10401:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10402: 
                   10403:   double agedeb;
                   10404:   double ***p3mat;
                   10405: 
1.201     brouard  10406:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10407:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10408:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10409:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10410:     }
                   10411:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10412:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10413:   
                   10414:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10415:     /*if (stepm<=24) stepsize=2;*/
                   10416: 
                   10417:     agelim=AGESUP;
                   10418:     hstepm=stepsize*YEARM; /* Every year of age */
                   10419:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10420:                
1.180     brouard  10421:     /* hstepm=1;   aff par mois*/
                   10422:     pstamp(ficrespij);
                   10423:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10424:     i1= pow(2,cptcoveff);
1.218     brouard  10425:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10426:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10427:                /*      k=k+1;  */
1.235     brouard  10428:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10429:     for(k=1; k<=i1;k++){
1.253     brouard  10430:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10431:        continue;
1.183     brouard  10432:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10433:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10434:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10435:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10436:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10437:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10438:       }
1.183     brouard  10439:       fprintf(ficrespij,"******\n");
                   10440:       
                   10441:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10442:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10443:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10444:        
                   10445:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10446:        
1.183     brouard  10447:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10448:        oldm=oldms;savm=savms;
1.235     brouard  10449:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10450:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10451:        for(i=1; i<=nlstate;i++)
                   10452:          for(j=1; j<=nlstate+ndeath;j++)
                   10453:            fprintf(ficrespij," %1d-%1d",i,j);
                   10454:        fprintf(ficrespij,"\n");
                   10455:        for (h=0; h<=nhstepm; h++){
                   10456:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10457:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10458:          for(i=1; i<=nlstate;i++)
                   10459:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10460:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10461:          fprintf(ficrespij,"\n");
                   10462:        }
1.183     brouard  10463:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10464:        fprintf(ficrespij,"\n");
                   10465:       }
1.180     brouard  10466:       /*}*/
                   10467:     }
1.218     brouard  10468:     return 0;
1.180     brouard  10469: }
1.218     brouard  10470:  
                   10471:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10472:     /*------------- h Bij x at various ages ------------*/
                   10473: 
                   10474:   int stepsize;
1.218     brouard  10475:   /* int agelim; */
                   10476:        int ageminl;
1.217     brouard  10477:   int hstepm;
                   10478:   int nhstepm;
1.238     brouard  10479:   int h, i, i1, j, k, nres;
1.218     brouard  10480:        
1.217     brouard  10481:   double agedeb;
                   10482:   double ***p3mat;
1.218     brouard  10483:        
                   10484:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10485:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10486:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10487:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10488:   }
                   10489:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10490:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10491:   
                   10492:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10493:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10494:   
1.218     brouard  10495:   /* agelim=AGESUP; */
                   10496:   ageminl=30;
                   10497:   hstepm=stepsize*YEARM; /* Every year of age */
                   10498:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10499:   
                   10500:   /* hstepm=1;   aff par mois*/
                   10501:   pstamp(ficrespijb);
1.255     brouard  10502:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10503:   i1= pow(2,cptcoveff);
1.218     brouard  10504:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10505:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10506:   /*   k=k+1;  */
1.238     brouard  10507:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10508:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10509:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10510:        continue;
                   10511:       fprintf(ficrespijb,"\n#****** ");
                   10512:       for(j=1;j<=cptcoveff;j++)
                   10513:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10514:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10515:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10516:       }
                   10517:       fprintf(ficrespijb,"******\n");
1.264     brouard  10518:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10519:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10520:        continue;
                   10521:       }
                   10522:       
                   10523:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10524:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10525:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10526:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10527:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10528:        
                   10529:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10530:        
1.266     brouard  10531:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10532:        /* and memory limitations if stepm is small */
                   10533: 
1.238     brouard  10534:        /* oldm=oldms;savm=savms; */
                   10535:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10536:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10537:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10538:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10539:        for(i=1; i<=nlstate;i++)
                   10540:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10541:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10542:        fprintf(ficrespijb,"\n");
1.238     brouard  10543:        for (h=0; h<=nhstepm; h++){
                   10544:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10545:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10546:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10547:          for(i=1; i<=nlstate;i++)
                   10548:            for(j=1; j<=nlstate+ndeath;j++)
                   10549:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10550:          fprintf(ficrespijb,"\n");
                   10551:        }
                   10552:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10553:        fprintf(ficrespijb,"\n");
                   10554:       } /* end age deb */
                   10555:     } /* end combination */
                   10556:   } /* end nres */
1.218     brouard  10557:   return 0;
                   10558:  } /*  hBijx */
1.217     brouard  10559: 
1.180     brouard  10560: 
1.136     brouard  10561: /***********************************************/
                   10562: /**************** Main Program *****************/
                   10563: /***********************************************/
                   10564: 
                   10565: int main(int argc, char *argv[])
                   10566: {
                   10567: #ifdef GSL
                   10568:   const gsl_multimin_fminimizer_type *T;
                   10569:   size_t iteri = 0, it;
                   10570:   int rval = GSL_CONTINUE;
                   10571:   int status = GSL_SUCCESS;
                   10572:   double ssval;
                   10573: #endif
                   10574:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10575:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10576:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10577:   int jj, ll, li, lj, lk;
1.136     brouard  10578:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10579:   int num_filled;
1.136     brouard  10580:   int itimes;
                   10581:   int NDIM=2;
                   10582:   int vpopbased=0;
1.235     brouard  10583:   int nres=0;
1.258     brouard  10584:   int endishere=0;
1.136     brouard  10585: 
1.164     brouard  10586:   char ca[32], cb[32];
1.136     brouard  10587:   /*  FILE *fichtm; *//* Html File */
                   10588:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10589:   struct stat info;
1.191     brouard  10590:   double agedeb=0.;
1.194     brouard  10591: 
                   10592:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10593:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10594: 
1.165     brouard  10595:   double fret;
1.191     brouard  10596:   double dum=0.; /* Dummy variable */
1.136     brouard  10597:   double ***p3mat;
1.218     brouard  10598:   /* double ***mobaverage; */
1.164     brouard  10599: 
                   10600:   char line[MAXLINE];
1.197     brouard  10601:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10602: 
1.234     brouard  10603:   char  modeltemp[MAXLINE];
1.230     brouard  10604:   char resultline[MAXLINE];
                   10605:   
1.136     brouard  10606:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10607:   char *tok, *val; /* pathtot */
1.136     brouard  10608:   int firstobs=1, lastobs=10;
1.195     brouard  10609:   int c,  h , cpt, c2;
1.191     brouard  10610:   int jl=0;
                   10611:   int i1, j1, jk, stepsize=0;
1.194     brouard  10612:   int count=0;
                   10613: 
1.164     brouard  10614:   int *tab; 
1.136     brouard  10615:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10616:   int backcast=0;
1.136     brouard  10617:   int mobilav=0,popforecast=0;
1.191     brouard  10618:   int hstepm=0, nhstepm=0;
1.136     brouard  10619:   int agemortsup;
                   10620:   float  sumlpop=0.;
                   10621:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10622:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10623: 
1.191     brouard  10624:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10625:   double ftolpl=FTOL;
                   10626:   double **prlim;
1.217     brouard  10627:   double **bprlim;
1.136     brouard  10628:   double ***param; /* Matrix of parameters */
1.251     brouard  10629:   double ***paramstart; /* Matrix of starting parameter values */
                   10630:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10631:   double **matcov; /* Matrix of covariance */
1.203     brouard  10632:   double **hess; /* Hessian matrix */
1.136     brouard  10633:   double ***delti3; /* Scale */
                   10634:   double *delti; /* Scale */
                   10635:   double ***eij, ***vareij;
                   10636:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10637: 
1.136     brouard  10638:   double *epj, vepp;
1.164     brouard  10639: 
1.273   ! brouard  10640:   double dateprev1, dateprev2;
        !          10641:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
        !          10642:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10643: 
1.136     brouard  10644:   double **ximort;
1.145     brouard  10645:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10646:   int *dcwave;
                   10647: 
1.164     brouard  10648:   char z[1]="c";
1.136     brouard  10649: 
                   10650:   /*char  *strt;*/
                   10651:   char strtend[80];
1.126     brouard  10652: 
1.164     brouard  10653: 
1.126     brouard  10654: /*   setlocale (LC_ALL, ""); */
                   10655: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10656: /*   textdomain (PACKAGE); */
                   10657: /*   setlocale (LC_CTYPE, ""); */
                   10658: /*   setlocale (LC_MESSAGES, ""); */
                   10659: 
                   10660:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10661:   rstart_time = time(NULL);  
                   10662:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10663:   start_time = *localtime(&rstart_time);
1.126     brouard  10664:   curr_time=start_time;
1.157     brouard  10665:   /*tml = *localtime(&start_time.tm_sec);*/
                   10666:   /* strcpy(strstart,asctime(&tml)); */
                   10667:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10668: 
                   10669: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10670: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10671: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10672: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10673: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10674: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10675: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10676: /*   strt=asctime(&tmg); */
                   10677: /*   printf("Time(after) =%s",strstart);  */
                   10678: /*  (void) time (&time_value);
                   10679: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10680: *  tm = *localtime(&time_value);
                   10681: *  strstart=asctime(&tm);
                   10682: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10683: */
                   10684: 
                   10685:   nberr=0; /* Number of errors and warnings */
                   10686:   nbwarn=0;
1.184     brouard  10687: #ifdef WIN32
                   10688:   _getcwd(pathcd, size);
                   10689: #else
1.126     brouard  10690:   getcwd(pathcd, size);
1.184     brouard  10691: #endif
1.191     brouard  10692:   syscompilerinfo(0);
1.196     brouard  10693:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10694:   if(argc <=1){
                   10695:     printf("\nEnter the parameter file name: ");
1.205     brouard  10696:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10697:       printf("ERROR Empty parameter file name\n");
                   10698:       goto end;
                   10699:     }
1.126     brouard  10700:     i=strlen(pathr);
                   10701:     if(pathr[i-1]=='\n')
                   10702:       pathr[i-1]='\0';
1.156     brouard  10703:     i=strlen(pathr);
1.205     brouard  10704:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10705:       pathr[i-1]='\0';
1.205     brouard  10706:     }
                   10707:     i=strlen(pathr);
                   10708:     if( i==0 ){
                   10709:       printf("ERROR Empty parameter file name\n");
                   10710:       goto end;
                   10711:     }
                   10712:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10713:       printf("Pathr |%s|\n",pathr);
                   10714:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10715:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10716:       strcpy (pathtot, val);
                   10717:       if(pathr[0] == '\0') break; /* Dirty */
                   10718:     }
                   10719:   }
                   10720:   else{
                   10721:     strcpy(pathtot,argv[1]);
                   10722:   }
                   10723:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10724:   /*cygwin_split_path(pathtot,path,optionfile);
                   10725:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10726:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10727: 
                   10728:   /* Split argv[0], imach program to get pathimach */
                   10729:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10730:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10731:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10732:  /*   strcpy(pathimach,argv[0]); */
                   10733:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10734:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10735:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10736: #ifdef WIN32
                   10737:   _chdir(path); /* Can be a relative path */
                   10738:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10739: #else
1.126     brouard  10740:   chdir(path); /* Can be a relative path */
1.184     brouard  10741:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10742: #endif
                   10743:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10744:   strcpy(command,"mkdir ");
                   10745:   strcat(command,optionfilefiname);
                   10746:   if((outcmd=system(command)) != 0){
1.169     brouard  10747:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10748:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10749:     /* fclose(ficlog); */
                   10750: /*     exit(1); */
                   10751:   }
                   10752: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10753: /*     perror("mkdir"); */
                   10754: /*   } */
                   10755: 
                   10756:   /*-------- arguments in the command line --------*/
                   10757: 
1.186     brouard  10758:   /* Main Log file */
1.126     brouard  10759:   strcat(filelog, optionfilefiname);
                   10760:   strcat(filelog,".log");    /* */
                   10761:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10762:     printf("Problem with logfile %s\n",filelog);
                   10763:     goto end;
                   10764:   }
                   10765:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10766:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10767:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10768:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10769:  path=%s \n\
                   10770:  optionfile=%s\n\
                   10771:  optionfilext=%s\n\
1.156     brouard  10772:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10773: 
1.197     brouard  10774:   syscompilerinfo(1);
1.167     brouard  10775: 
1.126     brouard  10776:   printf("Local time (at start):%s",strstart);
                   10777:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10778:   fflush(ficlog);
                   10779: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10780: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10781: 
                   10782:   /* */
                   10783:   strcpy(fileres,"r");
                   10784:   strcat(fileres, optionfilefiname);
1.201     brouard  10785:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10786:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10787:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10788: 
1.186     brouard  10789:   /* Main ---------arguments file --------*/
1.126     brouard  10790: 
                   10791:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10792:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10793:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10794:     fflush(ficlog);
1.149     brouard  10795:     /* goto end; */
                   10796:     exit(70); 
1.126     brouard  10797:   }
                   10798: 
                   10799: 
                   10800: 
                   10801:   strcpy(filereso,"o");
1.201     brouard  10802:   strcat(filereso,fileresu);
1.126     brouard  10803:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10804:     printf("Problem with Output resultfile: %s\n", filereso);
                   10805:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10806:     fflush(ficlog);
                   10807:     goto end;
                   10808:   }
                   10809: 
                   10810:   /* Reads comments: lines beginning with '#' */
                   10811:   numlinepar=0;
1.197     brouard  10812: 
                   10813:     /* First parameter line */
                   10814:   while(fgets(line, MAXLINE, ficpar)) {
                   10815:     /* If line starts with a # it is a comment */
                   10816:     if (line[0] == '#') {
                   10817:       numlinepar++;
                   10818:       fputs(line,stdout);
                   10819:       fputs(line,ficparo);
                   10820:       fputs(line,ficlog);
                   10821:       continue;
                   10822:     }else
                   10823:       break;
                   10824:   }
                   10825:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10826:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10827:     if (num_filled != 5) {
                   10828:       printf("Should be 5 parameters\n");
                   10829:     }
1.126     brouard  10830:     numlinepar++;
1.197     brouard  10831:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   10832:   }
                   10833:   /* Second parameter line */
                   10834:   while(fgets(line, MAXLINE, ficpar)) {
                   10835:     /* If line starts with a # it is a comment */
                   10836:     if (line[0] == '#') {
                   10837:       numlinepar++;
                   10838:       fputs(line,stdout);
                   10839:       fputs(line,ficparo);
                   10840:       fputs(line,ficlog);
                   10841:       continue;
                   10842:     }else
                   10843:       break;
                   10844:   }
1.223     brouard  10845:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   10846:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   10847:     if (num_filled != 11) {
                   10848:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  10849:       printf("but line=%s\n",line);
1.197     brouard  10850:     }
1.223     brouard  10851:     printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  10852:   }
1.203     brouard  10853:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  10854:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  10855:   /* Third parameter line */
                   10856:   while(fgets(line, MAXLINE, ficpar)) {
                   10857:     /* If line starts with a # it is a comment */
                   10858:     if (line[0] == '#') {
                   10859:       numlinepar++;
                   10860:       fputs(line,stdout);
                   10861:       fputs(line,ficparo);
                   10862:       fputs(line,ficlog);
                   10863:       continue;
                   10864:     }else
                   10865:       break;
                   10866:   }
1.201     brouard  10867:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.263     brouard  10868:     if (num_filled == 0){
                   10869:       printf("ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10870:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' WITHOUT space:'%s'\n",num_filled, line);
                   10871:       model[0]='\0';
                   10872:       goto end;
                   10873:     } else if (num_filled != 1){
1.197     brouard  10874:       printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10875:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
                   10876:       model[0]='\0';
                   10877:       goto end;
                   10878:     }
                   10879:     else{
                   10880:       if (model[0]=='+'){
                   10881:        for(i=1; i<=strlen(model);i++)
                   10882:          modeltemp[i-1]=model[i];
1.201     brouard  10883:        strcpy(model,modeltemp); 
1.197     brouard  10884:       }
                   10885:     }
1.199     brouard  10886:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  10887:     printf("model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  10888:   }
                   10889:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   10890:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   10891:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.223     brouard  10892:   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
                   10893:   fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model);
1.126     brouard  10894:   fflush(ficlog);
1.190     brouard  10895:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   10896:   if(model[0]=='#'){
1.187     brouard  10897:     printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
                   10898:  'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
                   10899:  'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");         \
                   10900:     if(mle != -1){
                   10901:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
                   10902:       exit(1);
                   10903:     }
                   10904:   }
1.126     brouard  10905:   while((c=getc(ficpar))=='#' && c!= EOF){
                   10906:     ungetc(c,ficpar);
                   10907:     fgets(line, MAXLINE, ficpar);
                   10908:     numlinepar++;
1.195     brouard  10909:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   10910:       z[0]=line[1];
                   10911:     }
                   10912:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  10913:     fputs(line, stdout);
                   10914:     //puts(line);
1.126     brouard  10915:     fputs(line,ficparo);
                   10916:     fputs(line,ficlog);
                   10917:   }
                   10918:   ungetc(c,ficpar);
                   10919: 
                   10920:    
1.145     brouard  10921:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  10922:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   10923:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   10924:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  10925:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   10926:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   10927:      v1+v2*age+v2*v3 makes cptcovn = 3
                   10928:   */
                   10929:   if (strlen(model)>1) 
1.187     brouard  10930:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  10931:   else
1.187     brouard  10932:     ncovmodel=2; /* Constant and age */
1.133     brouard  10933:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   10934:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  10935:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   10936:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10937:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   10938:     fflush(stdout);
                   10939:     fclose (ficlog);
                   10940:     goto end;
                   10941:   }
1.126     brouard  10942:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10943:   delti=delti3[1][1];
                   10944:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   10945:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  10946: /* We could also provide initial parameters values giving by simple logistic regression 
                   10947:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   10948:       /* for(i=1;i<nlstate;i++){ */
                   10949:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   10950:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   10951:       /* } */
1.126     brouard  10952:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  10953:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   10954:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10955:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   10956:     fclose (ficparo);
                   10957:     fclose (ficlog);
                   10958:     goto end;
                   10959:     exit(0);
1.220     brouard  10960:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  10961:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  10962:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   10963:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  10964:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   10965:     matcov=matrix(1,npar,1,npar);
1.203     brouard  10966:     hess=matrix(1,npar,1,npar);
1.220     brouard  10967:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  10968:     /* Read guessed parameters */
1.126     brouard  10969:     /* Reads comments: lines beginning with '#' */
                   10970:     while((c=getc(ficpar))=='#' && c!= EOF){
                   10971:       ungetc(c,ficpar);
                   10972:       fgets(line, MAXLINE, ficpar);
                   10973:       numlinepar++;
1.141     brouard  10974:       fputs(line,stdout);
1.126     brouard  10975:       fputs(line,ficparo);
                   10976:       fputs(line,ficlog);
                   10977:     }
                   10978:     ungetc(c,ficpar);
                   10979:     
                   10980:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  10981:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  10982:     for(i=1; i <=nlstate; i++){
1.234     brouard  10983:       j=0;
1.126     brouard  10984:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  10985:        if(jj==i) continue;
                   10986:        j++;
                   10987:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   10988:        if ((i1 != i) || (j1 != jj)){
                   10989:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  10990: It might be a problem of design; if ncovcol and the model are correct\n \
                   10991: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  10992:          exit(1);
                   10993:        }
                   10994:        fprintf(ficparo,"%1d%1d",i1,j1);
                   10995:        if(mle==1)
                   10996:          printf("%1d%1d",i,jj);
                   10997:        fprintf(ficlog,"%1d%1d",i,jj);
                   10998:        for(k=1; k<=ncovmodel;k++){
                   10999:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11000:          if(mle==1){
                   11001:            printf(" %lf",param[i][j][k]);
                   11002:            fprintf(ficlog," %lf",param[i][j][k]);
                   11003:          }
                   11004:          else
                   11005:            fprintf(ficlog," %lf",param[i][j][k]);
                   11006:          fprintf(ficparo," %lf",param[i][j][k]);
                   11007:        }
                   11008:        fscanf(ficpar,"\n");
                   11009:        numlinepar++;
                   11010:        if(mle==1)
                   11011:          printf("\n");
                   11012:        fprintf(ficlog,"\n");
                   11013:        fprintf(ficparo,"\n");
1.126     brouard  11014:       }
                   11015:     }  
                   11016:     fflush(ficlog);
1.234     brouard  11017:     
1.251     brouard  11018:     /* Reads parameters values */
1.126     brouard  11019:     p=param[1][1];
1.251     brouard  11020:     pstart=paramstart[1][1];
1.126     brouard  11021:     
                   11022:     /* Reads comments: lines beginning with '#' */
                   11023:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11024:       ungetc(c,ficpar);
                   11025:       fgets(line, MAXLINE, ficpar);
                   11026:       numlinepar++;
1.141     brouard  11027:       fputs(line,stdout);
1.126     brouard  11028:       fputs(line,ficparo);
                   11029:       fputs(line,ficlog);
                   11030:     }
                   11031:     ungetc(c,ficpar);
                   11032: 
                   11033:     for(i=1; i <=nlstate; i++){
                   11034:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11035:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11036:        if ( (i1-i) * (j1-j) != 0){
                   11037:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11038:          exit(1);
                   11039:        }
                   11040:        printf("%1d%1d",i,j);
                   11041:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11042:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11043:        for(k=1; k<=ncovmodel;k++){
                   11044:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11045:          printf(" %le",delti3[i][j][k]);
                   11046:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11047:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11048:        }
                   11049:        fscanf(ficpar,"\n");
                   11050:        numlinepar++;
                   11051:        printf("\n");
                   11052:        fprintf(ficparo,"\n");
                   11053:        fprintf(ficlog,"\n");
1.126     brouard  11054:       }
                   11055:     }
                   11056:     fflush(ficlog);
1.234     brouard  11057:     
1.145     brouard  11058:     /* Reads covariance matrix */
1.126     brouard  11059:     delti=delti3[1][1];
1.220     brouard  11060:                
                   11061:                
1.126     brouard  11062:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11063:                
1.126     brouard  11064:     /* Reads comments: lines beginning with '#' */
                   11065:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11066:       ungetc(c,ficpar);
                   11067:       fgets(line, MAXLINE, ficpar);
                   11068:       numlinepar++;
1.141     brouard  11069:       fputs(line,stdout);
1.126     brouard  11070:       fputs(line,ficparo);
                   11071:       fputs(line,ficlog);
                   11072:     }
                   11073:     ungetc(c,ficpar);
1.220     brouard  11074:                
1.126     brouard  11075:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11076:     hess=matrix(1,npar,1,npar);
1.131     brouard  11077:     for(i=1; i <=npar; i++)
                   11078:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11079:                
1.194     brouard  11080:     /* Scans npar lines */
1.126     brouard  11081:     for(i=1; i <=npar; i++){
1.226     brouard  11082:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11083:       if(count != 3){
1.226     brouard  11084:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11085: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11086: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11087:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11088: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11089: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11090:        exit(1);
1.220     brouard  11091:       }else{
1.226     brouard  11092:        if(mle==1)
                   11093:          printf("%1d%1d%d",i1,j1,jk);
                   11094:       }
                   11095:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11096:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11097:       for(j=1; j <=i; j++){
1.226     brouard  11098:        fscanf(ficpar," %le",&matcov[i][j]);
                   11099:        if(mle==1){
                   11100:          printf(" %.5le",matcov[i][j]);
                   11101:        }
                   11102:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11103:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11104:       }
                   11105:       fscanf(ficpar,"\n");
                   11106:       numlinepar++;
                   11107:       if(mle==1)
1.220     brouard  11108:                                printf("\n");
1.126     brouard  11109:       fprintf(ficlog,"\n");
                   11110:       fprintf(ficparo,"\n");
                   11111:     }
1.194     brouard  11112:     /* End of read covariance matrix npar lines */
1.126     brouard  11113:     for(i=1; i <=npar; i++)
                   11114:       for(j=i+1;j<=npar;j++)
1.226     brouard  11115:        matcov[i][j]=matcov[j][i];
1.126     brouard  11116:     
                   11117:     if(mle==1)
                   11118:       printf("\n");
                   11119:     fprintf(ficlog,"\n");
                   11120:     
                   11121:     fflush(ficlog);
                   11122:     
                   11123:     /*-------- Rewriting parameter file ----------*/
                   11124:     strcpy(rfileres,"r");    /* "Rparameterfile */
                   11125:     strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
                   11126:     strcat(rfileres,".");    /* */
                   11127:     strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11128:     if((ficres =fopen(rfileres,"w"))==NULL) {
1.201     brouard  11129:       printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11130:       fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
1.126     brouard  11131:     }
                   11132:     fprintf(ficres,"#%s\n",version);
                   11133:   }    /* End of mle != -3 */
1.218     brouard  11134:   
1.186     brouard  11135:   /*  Main data
                   11136:    */
1.126     brouard  11137:   n= lastobs;
                   11138:   num=lvector(1,n);
                   11139:   moisnais=vector(1,n);
                   11140:   annais=vector(1,n);
                   11141:   moisdc=vector(1,n);
                   11142:   andc=vector(1,n);
1.220     brouard  11143:   weight=vector(1,n);
1.126     brouard  11144:   agedc=vector(1,n);
                   11145:   cod=ivector(1,n);
1.220     brouard  11146:   for(i=1;i<=n;i++){
1.234     brouard  11147:     num[i]=0;
                   11148:     moisnais[i]=0;
                   11149:     annais[i]=0;
                   11150:     moisdc[i]=0;
                   11151:     andc[i]=0;
                   11152:     agedc[i]=0;
                   11153:     cod[i]=0;
                   11154:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11155:   }
1.126     brouard  11156:   mint=matrix(1,maxwav,1,n);
                   11157:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11158:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11159:   tab=ivector(1,NCOVMAX);
1.144     brouard  11160:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11161:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11162: 
1.136     brouard  11163:   /* Reads data from file datafile */
                   11164:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11165:     goto end;
                   11166: 
                   11167:   /* Calculation of the number of parameters from char model */
1.234     brouard  11168:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11169:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11170:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11171:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11172:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11173:   */
                   11174:   
                   11175:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11176:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11177:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11178:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11179:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11180:   TvarF=ivector(1,NCOVMAX); /*  */
                   11181:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11182:   TvarV=ivector(1,NCOVMAX); /*  */
                   11183:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11184:   TvarA=ivector(1,NCOVMAX); /*  */
                   11185:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11186:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11187:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11188:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11189:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11190:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11191:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11192:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11193:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11194: 
1.230     brouard  11195:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11196:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11197:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11198:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11199:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11200:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11201:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11202:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11203:   */
                   11204:   /* For model-covariate k tells which data-covariate to use but
                   11205:     because this model-covariate is a construction we invent a new column
                   11206:     ncovcol + k1
                   11207:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11208:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11209:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11210:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11211:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11212:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11213:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11214:   */
1.145     brouard  11215:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11216:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11217:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11218:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11219:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11220:                         4 covariates (3 plus signs)
                   11221:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11222:                      */  
1.230     brouard  11223:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11224:                                * individual dummy, fixed or varying:
                   11225:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11226:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11227:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11228:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11229:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11230:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11231:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11232:                                * individual quantitative, fixed or varying:
                   11233:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11234:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11235:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11236: /* Main decodemodel */
                   11237: 
1.187     brouard  11238: 
1.223     brouard  11239:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11240:     goto end;
                   11241: 
1.137     brouard  11242:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11243:     nbwarn++;
                   11244:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11245:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11246:   }
1.136     brouard  11247:     /*  if(mle==1){*/
1.137     brouard  11248:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11249:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11250:   }
                   11251: 
                   11252:     /*-calculation of age at interview from date of interview and age at death -*/
                   11253:   agev=matrix(1,maxwav,1,imx);
                   11254: 
                   11255:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11256:     goto end;
                   11257: 
1.126     brouard  11258: 
1.136     brouard  11259:   agegomp=(int)agemin;
                   11260:   free_vector(moisnais,1,n);
                   11261:   free_vector(annais,1,n);
1.126     brouard  11262:   /* free_matrix(mint,1,maxwav,1,n);
                   11263:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11264:   /* free_vector(moisdc,1,n); */
                   11265:   /* free_vector(andc,1,n); */
1.145     brouard  11266:   /* */
                   11267:   
1.126     brouard  11268:   wav=ivector(1,imx);
1.214     brouard  11269:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11270:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11271:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11272:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11273:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11274:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11275:    
                   11276:   /* Concatenates waves */
1.214     brouard  11277:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11278:      Death is a valid wave (if date is known).
                   11279:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11280:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11281:      and mw[mi+1][i]. dh depends on stepm.
                   11282:   */
                   11283: 
1.126     brouard  11284:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11285:   /* Concatenates waves */
1.145     brouard  11286:  
1.215     brouard  11287:   free_vector(moisdc,1,n);
                   11288:   free_vector(andc,1,n);
                   11289: 
1.126     brouard  11290:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11291:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11292:   ncodemax[1]=1;
1.145     brouard  11293:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11294:   cptcoveff=0;
1.220     brouard  11295:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11296:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11297:   }
                   11298:   
                   11299:   ncovcombmax=pow(2,cptcoveff);
                   11300:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11301:   for(i=1;i<ncovcombmax;i++)
                   11302:     invalidvarcomb[i]=0;
                   11303:   
1.211     brouard  11304:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11305:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11306:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11307:   
1.200     brouard  11308:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11309:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11310:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11311:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11312:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11313:    * (currently 0 or 1) in the data.
                   11314:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11315:    * corresponding modality (h,j).
                   11316:    */
                   11317: 
1.145     brouard  11318:   h=0;
                   11319:   /*if (cptcovn > 0) */
1.126     brouard  11320:   m=pow(2,cptcoveff);
                   11321:  
1.144     brouard  11322:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11323:           * For k=4 covariates, h goes from 1 to m=2**k
                   11324:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11325:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11326:           *     h\k   1     2     3     4
1.143     brouard  11327:           *______________________________  
                   11328:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11329:           *     2     2     1     1     1
                   11330:           *     3 i=2 1     2     1     1
                   11331:           *     4     2     2     1     1
                   11332:           *     5 i=3 1 i=2 1     2     1
                   11333:           *     6     2     1     2     1
                   11334:           *     7 i=4 1     2     2     1
                   11335:           *     8     2     2     2     1
1.197     brouard  11336:           *     9 i=5 1 i=3 1 i=2 1     2
                   11337:           *    10     2     1     1     2
                   11338:           *    11 i=6 1     2     1     2
                   11339:           *    12     2     2     1     2
                   11340:           *    13 i=7 1 i=4 1     2     2    
                   11341:           *    14     2     1     2     2
                   11342:           *    15 i=8 1     2     2     2
                   11343:           *    16     2     2     2     2
1.143     brouard  11344:           */
1.212     brouard  11345:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11346:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11347:      * and the value of each covariate?
                   11348:      * V1=1, V2=1, V3=2, V4=1 ?
                   11349:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11350:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11351:      * In order to get the real value in the data, we use nbcode
                   11352:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11353:      * We are keeping this crazy system in order to be able (in the future?) 
                   11354:      * to have more than 2 values (0 or 1) for a covariate.
                   11355:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11356:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11357:      *              bbbbbbbb
                   11358:      *              76543210     
                   11359:      *   h-1        00000101 (6-1=5)
1.219     brouard  11360:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11361:      *           &
                   11362:      *     1        00000001 (1)
1.219     brouard  11363:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11364:      *          +1= 00000001 =1 
1.211     brouard  11365:      *
                   11366:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11367:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11368:      *    >>k'            11
                   11369:      *          &   00000001
                   11370:      *            = 00000001
                   11371:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11372:      * Reverse h=6 and m=16?
                   11373:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11374:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11375:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11376:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11377:      * V3=decodtabm(14,3,2**4)=2
                   11378:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11379:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11380:      *          &1 000000001
                   11381:      *           = 000000001
                   11382:      *         +1= 000000010 =2
                   11383:      *                  2211
                   11384:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11385:      *                  V3=2
1.220     brouard  11386:                 * codtabm and decodtabm are identical
1.211     brouard  11387:      */
                   11388: 
1.145     brouard  11389: 
                   11390:  free_ivector(Ndum,-1,NCOVMAX);
                   11391: 
                   11392: 
1.126     brouard  11393:     
1.186     brouard  11394:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11395:   strcpy(optionfilegnuplot,optionfilefiname);
                   11396:   if(mle==-3)
1.201     brouard  11397:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11398:   strcat(optionfilegnuplot,".gp");
                   11399: 
                   11400:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11401:     printf("Problem with file %s",optionfilegnuplot);
                   11402:   }
                   11403:   else{
1.204     brouard  11404:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11405:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11406:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11407:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11408:   }
                   11409:   /*  fclose(ficgp);*/
1.186     brouard  11410: 
                   11411: 
                   11412:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11413: 
                   11414:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11415:   if(mle==-3)
1.201     brouard  11416:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11417:   strcat(optionfilehtm,".htm");
                   11418:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11419:     printf("Problem with %s \n",optionfilehtm);
                   11420:     exit(0);
1.126     brouard  11421:   }
                   11422: 
                   11423:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11424:   strcat(optionfilehtmcov,"-cov.htm");
                   11425:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11426:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11427:   }
                   11428:   else{
                   11429:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11430: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11431: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11432:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11433:   }
                   11434: 
1.213     brouard  11435:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11436: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11437: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11438: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11439: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11440: \n\
                   11441: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11442:  <ul><li><h4>Parameter files</h4>\n\
                   11443:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11444:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11445:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11446:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11447:  - Date and time at start: %s</ul>\n",\
                   11448:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11449:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11450:          fileres,fileres,\
                   11451:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11452:   fflush(fichtm);
                   11453: 
                   11454:   strcpy(pathr,path);
                   11455:   strcat(pathr,optionfilefiname);
1.184     brouard  11456: #ifdef WIN32
                   11457:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11458: #else
1.126     brouard  11459:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11460: #endif
                   11461:          
1.126     brouard  11462:   
1.220     brouard  11463:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11464:                 and for any valid combination of covariates
1.126     brouard  11465:      and prints on file fileres'p'. */
1.251     brouard  11466:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11467:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11468: 
                   11469:   fprintf(fichtm,"\n");
                   11470:   fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
                   11471: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11472: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
                   11473:          imx,agemin,agemax,jmin,jmax,jmean);
                   11474:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11475:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11476:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11477:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11478:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11479: 
1.126     brouard  11480:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11481:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11482:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11483: 
                   11484:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11485:   /* For mortality only */
1.126     brouard  11486:   if (mle==-3){
1.136     brouard  11487:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11488:     for(i=1;i<=NDIM;i++)
                   11489:       for(j=1;j<=NDIM;j++)
                   11490:        ximort[i][j]=0.;
1.186     brouard  11491:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11492:     cens=ivector(1,n);
                   11493:     ageexmed=vector(1,n);
                   11494:     agecens=vector(1,n);
                   11495:     dcwave=ivector(1,n);
1.223     brouard  11496:                
1.126     brouard  11497:     for (i=1; i<=imx; i++){
                   11498:       dcwave[i]=-1;
                   11499:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11500:        if (s[m][i]>nlstate) {
                   11501:          dcwave[i]=m;
                   11502:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11503:          break;
                   11504:        }
1.126     brouard  11505:     }
1.226     brouard  11506:     
1.126     brouard  11507:     for (i=1; i<=imx; i++) {
                   11508:       if (wav[i]>0){
1.226     brouard  11509:        ageexmed[i]=agev[mw[1][i]][i];
                   11510:        j=wav[i];
                   11511:        agecens[i]=1.; 
                   11512:        
                   11513:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11514:          agecens[i]=agev[mw[j][i]][i];
                   11515:          cens[i]= 1;
                   11516:        }else if (ageexmed[i]< 1) 
                   11517:          cens[i]= -1;
                   11518:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11519:          cens[i]=0 ;
1.126     brouard  11520:       }
                   11521:       else cens[i]=-1;
                   11522:     }
                   11523:     
                   11524:     for (i=1;i<=NDIM;i++) {
                   11525:       for (j=1;j<=NDIM;j++)
1.226     brouard  11526:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11527:     }
                   11528:     
1.145     brouard  11529:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11530:     /*printf("%lf %lf", p[1], p[2]);*/
                   11531:     
                   11532:     
1.136     brouard  11533: #ifdef GSL
                   11534:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11535: #else
1.126     brouard  11536:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11537: #endif
1.201     brouard  11538:     strcpy(filerespow,"POW-MORT_"); 
                   11539:     strcat(filerespow,fileresu);
1.126     brouard  11540:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11541:       printf("Problem with resultfile: %s\n", filerespow);
                   11542:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11543:     }
1.136     brouard  11544: #ifdef GSL
                   11545:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11546: #else
1.126     brouard  11547:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11548: #endif
1.126     brouard  11549:     /*  for (i=1;i<=nlstate;i++)
                   11550:        for(j=1;j<=nlstate+ndeath;j++)
                   11551:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11552:     */
                   11553:     fprintf(ficrespow,"\n");
1.136     brouard  11554: #ifdef GSL
                   11555:     /* gsl starts here */ 
                   11556:     T = gsl_multimin_fminimizer_nmsimplex;
                   11557:     gsl_multimin_fminimizer *sfm = NULL;
                   11558:     gsl_vector *ss, *x;
                   11559:     gsl_multimin_function minex_func;
                   11560: 
                   11561:     /* Initial vertex size vector */
                   11562:     ss = gsl_vector_alloc (NDIM);
                   11563:     
                   11564:     if (ss == NULL){
                   11565:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11566:     }
                   11567:     /* Set all step sizes to 1 */
                   11568:     gsl_vector_set_all (ss, 0.001);
                   11569: 
                   11570:     /* Starting point */
1.126     brouard  11571:     
1.136     brouard  11572:     x = gsl_vector_alloc (NDIM);
                   11573:     
                   11574:     if (x == NULL){
                   11575:       gsl_vector_free(ss);
                   11576:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11577:     }
                   11578:   
                   11579:     /* Initialize method and iterate */
                   11580:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11581:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11582:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11583:     gsl_vector_set(x, 0, p[1]);
                   11584:     gsl_vector_set(x, 1, p[2]);
                   11585: 
                   11586:     minex_func.f = &gompertz_f;
                   11587:     minex_func.n = NDIM;
                   11588:     minex_func.params = (void *)&p; /* ??? */
                   11589:     
                   11590:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11591:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11592:     
                   11593:     printf("Iterations beginning .....\n\n");
                   11594:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11595: 
                   11596:     iteri=0;
                   11597:     while (rval == GSL_CONTINUE){
                   11598:       iteri++;
                   11599:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11600:       
                   11601:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11602:       fflush(0);
                   11603:       
                   11604:       if (status) 
                   11605:         break;
                   11606:       
                   11607:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11608:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11609:       
                   11610:       if (rval == GSL_SUCCESS)
                   11611:         printf ("converged to a local maximum at\n");
                   11612:       
                   11613:       printf("%5d ", iteri);
                   11614:       for (it = 0; it < NDIM; it++){
                   11615:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11616:       }
                   11617:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11618:     }
                   11619:     
                   11620:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11621:     
                   11622:     gsl_vector_free(x); /* initial values */
                   11623:     gsl_vector_free(ss); /* inital step size */
                   11624:     for (it=0; it<NDIM; it++){
                   11625:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11626:       fprintf(ficrespow," %.12lf", p[it]);
                   11627:     }
                   11628:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11629: #endif
                   11630: #ifdef POWELL
                   11631:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11632: #endif  
1.126     brouard  11633:     fclose(ficrespow);
                   11634:     
1.203     brouard  11635:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11636: 
                   11637:     for(i=1; i <=NDIM; i++)
                   11638:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11639:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11640:     
                   11641:     printf("\nCovariance matrix\n ");
1.203     brouard  11642:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11643:     for(i=1; i <=NDIM; i++) {
                   11644:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11645:                                printf("%f ",matcov[i][j]);
                   11646:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11647:       }
1.203     brouard  11648:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11649:     }
                   11650:     
                   11651:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11652:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11653:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11654:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11655:     }
1.126     brouard  11656:     lsurv=vector(1,AGESUP);
                   11657:     lpop=vector(1,AGESUP);
                   11658:     tpop=vector(1,AGESUP);
                   11659:     lsurv[agegomp]=100000;
                   11660:     
                   11661:     for (k=agegomp;k<=AGESUP;k++) {
                   11662:       agemortsup=k;
                   11663:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11664:     }
                   11665:     
                   11666:     for (k=agegomp;k<agemortsup;k++)
                   11667:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11668:     
                   11669:     for (k=agegomp;k<agemortsup;k++){
                   11670:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11671:       sumlpop=sumlpop+lpop[k];
                   11672:     }
                   11673:     
                   11674:     tpop[agegomp]=sumlpop;
                   11675:     for (k=agegomp;k<(agemortsup-3);k++){
                   11676:       /*  tpop[k+1]=2;*/
                   11677:       tpop[k+1]=tpop[k]-lpop[k];
                   11678:     }
                   11679:     
                   11680:     
                   11681:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11682:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11683:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11684:     
                   11685:     
                   11686:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11687:                ageminpar=50;
                   11688:                agemaxpar=100;
1.194     brouard  11689:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11690:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11691: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11692: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11693:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11694: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11695: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11696:     }else{
                   11697:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11698:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11699:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11700:                }
1.201     brouard  11701:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11702:                     stepm, weightopt,\
                   11703:                     model,imx,p,matcov,agemortsup);
                   11704:     
                   11705:     free_vector(lsurv,1,AGESUP);
                   11706:     free_vector(lpop,1,AGESUP);
                   11707:     free_vector(tpop,1,AGESUP);
1.220     brouard  11708:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11709:     free_ivector(cens,1,n);
                   11710:     free_vector(agecens,1,n);
                   11711:     free_ivector(dcwave,1,n);
1.220     brouard  11712: #ifdef GSL
1.136     brouard  11713: #endif
1.186     brouard  11714:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11715:   /* Standard  */
                   11716:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11717:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11718:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11719:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11720:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11721:     for (k=1; k<=npar;k++)
                   11722:       printf(" %d %8.5f",k,p[k]);
                   11723:     printf("\n");
1.205     brouard  11724:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11725:       /* mlikeli uses func not funcone */
1.247     brouard  11726:       /* for(i=1;i<nlstate;i++){ */
                   11727:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11728:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11729:       /* } */
1.205     brouard  11730:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11731:     }
                   11732:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11733:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11734:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11735:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11736:     }
                   11737:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11738:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11739:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11740:     for (k=1; k<=npar;k++)
                   11741:       printf(" %d %8.5f",k,p[k]);
                   11742:     printf("\n");
                   11743:     
                   11744:     /*--------- results files --------------*/
1.224     brouard  11745:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model);
1.126     brouard  11746:     
                   11747:     
                   11748:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11749:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11750:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11751:     for(i=1,jk=1; i <=nlstate; i++){
                   11752:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11753:        if (k != i) {
                   11754:          printf("%d%d ",i,k);
                   11755:          fprintf(ficlog,"%d%d ",i,k);
                   11756:          fprintf(ficres,"%1d%1d ",i,k);
                   11757:          for(j=1; j <=ncovmodel; j++){
                   11758:            printf("%12.7f ",p[jk]);
                   11759:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11760:            fprintf(ficres,"%12.7f ",p[jk]);
                   11761:            jk++; 
                   11762:          }
                   11763:          printf("\n");
                   11764:          fprintf(ficlog,"\n");
                   11765:          fprintf(ficres,"\n");
                   11766:        }
1.126     brouard  11767:       }
                   11768:     }
1.203     brouard  11769:     if(mle != 0){
                   11770:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11771:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11772:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11773:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11774:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11775:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11776:        for(k=1; k <=(nlstate+ndeath); k++){
                   11777:          if (k != i) {
                   11778:            printf("%d%d ",i,k);
                   11779:            fprintf(ficlog,"%d%d ",i,k);
                   11780:            for(j=1; j <=ncovmodel; j++){
                   11781:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11782:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11783:              jk++; 
                   11784:            }
                   11785:            printf("\n");
                   11786:            fprintf(ficlog,"\n");
                   11787:          }
                   11788:        }
1.193     brouard  11789:       }
1.203     brouard  11790:     } /* end of hesscov and Wald tests */
1.225     brouard  11791:     
1.203     brouard  11792:     /*  */
1.126     brouard  11793:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11794:     printf("# Scales (for hessian or gradient estimation)\n");
                   11795:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11796:     for(i=1,jk=1; i <=nlstate; i++){
                   11797:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11798:        if (j!=i) {
                   11799:          fprintf(ficres,"%1d%1d",i,j);
                   11800:          printf("%1d%1d",i,j);
                   11801:          fprintf(ficlog,"%1d%1d",i,j);
                   11802:          for(k=1; k<=ncovmodel;k++){
                   11803:            printf(" %.5e",delti[jk]);
                   11804:            fprintf(ficlog," %.5e",delti[jk]);
                   11805:            fprintf(ficres," %.5e",delti[jk]);
                   11806:            jk++;
                   11807:          }
                   11808:          printf("\n");
                   11809:          fprintf(ficlog,"\n");
                   11810:          fprintf(ficres,"\n");
                   11811:        }
1.126     brouard  11812:       }
                   11813:     }
                   11814:     
                   11815:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  11816:     if(mle >= 1) /* To big for the screen */
1.126     brouard  11817:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11818:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   11819:     /* # 121 Var(a12)\n\ */
                   11820:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   11821:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   11822:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   11823:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   11824:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   11825:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   11826:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   11827:     
                   11828:     
                   11829:     /* Just to have a covariance matrix which will be more understandable
                   11830:        even is we still don't want to manage dictionary of variables
                   11831:     */
                   11832:     for(itimes=1;itimes<=2;itimes++){
                   11833:       jj=0;
                   11834:       for(i=1; i <=nlstate; i++){
1.225     brouard  11835:        for(j=1; j <=nlstate+ndeath; j++){
                   11836:          if(j==i) continue;
                   11837:          for(k=1; k<=ncovmodel;k++){
                   11838:            jj++;
                   11839:            ca[0]= k+'a'-1;ca[1]='\0';
                   11840:            if(itimes==1){
                   11841:              if(mle>=1)
                   11842:                printf("#%1d%1d%d",i,j,k);
                   11843:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   11844:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   11845:            }else{
                   11846:              if(mle>=1)
                   11847:                printf("%1d%1d%d",i,j,k);
                   11848:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   11849:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   11850:            }
                   11851:            ll=0;
                   11852:            for(li=1;li <=nlstate; li++){
                   11853:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   11854:                if(lj==li) continue;
                   11855:                for(lk=1;lk<=ncovmodel;lk++){
                   11856:                  ll++;
                   11857:                  if(ll<=jj){
                   11858:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   11859:                    if(ll<jj){
                   11860:                      if(itimes==1){
                   11861:                        if(mle>=1)
                   11862:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11863:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11864:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   11865:                      }else{
                   11866:                        if(mle>=1)
                   11867:                          printf(" %.5e",matcov[jj][ll]); 
                   11868:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   11869:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   11870:                      }
                   11871:                    }else{
                   11872:                      if(itimes==1){
                   11873:                        if(mle>=1)
                   11874:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   11875:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   11876:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   11877:                      }else{
                   11878:                        if(mle>=1)
                   11879:                          printf(" %.7e",matcov[jj][ll]); 
                   11880:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   11881:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   11882:                      }
                   11883:                    }
                   11884:                  }
                   11885:                } /* end lk */
                   11886:              } /* end lj */
                   11887:            } /* end li */
                   11888:            if(mle>=1)
                   11889:              printf("\n");
                   11890:            fprintf(ficlog,"\n");
                   11891:            fprintf(ficres,"\n");
                   11892:            numlinepar++;
                   11893:          } /* end k*/
                   11894:        } /*end j */
1.126     brouard  11895:       } /* end i */
                   11896:     } /* end itimes */
                   11897:     
                   11898:     fflush(ficlog);
                   11899:     fflush(ficres);
1.225     brouard  11900:     while(fgets(line, MAXLINE, ficpar)) {
                   11901:       /* If line starts with a # it is a comment */
                   11902:       if (line[0] == '#') {
                   11903:        numlinepar++;
                   11904:        fputs(line,stdout);
                   11905:        fputs(line,ficparo);
                   11906:        fputs(line,ficlog);
                   11907:        continue;
                   11908:       }else
                   11909:        break;
                   11910:     }
                   11911:     
1.209     brouard  11912:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   11913:     /*   ungetc(c,ficpar); */
                   11914:     /*   fgets(line, MAXLINE, ficpar); */
                   11915:     /*   fputs(line,stdout); */
                   11916:     /*   fputs(line,ficparo); */
                   11917:     /* } */
                   11918:     /* ungetc(c,ficpar); */
1.126     brouard  11919:     
                   11920:     estepm=0;
1.209     brouard  11921:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  11922:       
                   11923:       if (num_filled != 6) {
                   11924:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11925:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   11926:        goto end;
                   11927:       }
                   11928:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   11929:     }
                   11930:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   11931:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   11932:     
1.209     brouard  11933:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  11934:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   11935:     if (fage <= 2) {
                   11936:       bage = ageminpar;
                   11937:       fage = agemaxpar;
                   11938:     }
                   11939:     
                   11940:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  11941:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   11942:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  11943:                
1.186     brouard  11944:     /* Other stuffs, more or less useful */    
1.254     brouard  11945:     while(fgets(line, MAXLINE, ficpar)) {
                   11946:       /* If line starts with a # it is a comment */
                   11947:       if (line[0] == '#') {
                   11948:        numlinepar++;
                   11949:        fputs(line,stdout);
                   11950:        fputs(line,ficparo);
                   11951:        fputs(line,ficlog);
                   11952:        continue;
                   11953:       }else
                   11954:        break;
                   11955:     }
                   11956: 
                   11957:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   11958:       
                   11959:       if (num_filled != 7) {
                   11960:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11961:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11962:        goto end;
                   11963:       }
                   11964:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11965:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11966:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   11967:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  11968:     }
1.254     brouard  11969: 
                   11970:     while(fgets(line, MAXLINE, ficpar)) {
                   11971:       /* If line starts with a # it is a comment */
                   11972:       if (line[0] == '#') {
                   11973:        numlinepar++;
                   11974:        fputs(line,stdout);
                   11975:        fputs(line,ficparo);
                   11976:        fputs(line,ficlog);
                   11977:        continue;
                   11978:       }else
                   11979:        break;
1.126     brouard  11980:     }
                   11981:     
                   11982:     
                   11983:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   11984:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   11985:     
1.254     brouard  11986:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   11987:       if (num_filled != 1) {
                   11988:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11989:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   11990:        goto end;
                   11991:       }
                   11992:       printf("pop_based=%d\n",popbased);
                   11993:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   11994:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   11995:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   11996:     }
                   11997:      
1.258     brouard  11998:     /* Results */
                   11999:     nresult=0;
                   12000:     do{
                   12001:       if(!fgets(line, MAXLINE, ficpar)){
                   12002:        endishere=1;
                   12003:        parameterline=14;
                   12004:       }else if (line[0] == '#') {
                   12005:        /* If line starts with a # it is a comment */
1.254     brouard  12006:        numlinepar++;
                   12007:        fputs(line,stdout);
                   12008:        fputs(line,ficparo);
                   12009:        fputs(line,ficlog);
                   12010:        continue;
1.258     brouard  12011:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12012:        parameterline=11;
                   12013:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12014:        parameterline=12;
                   12015:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12016:        parameterline=13;
                   12017:       else{
                   12018:        parameterline=14;
1.254     brouard  12019:       }
1.258     brouard  12020:       switch (parameterline){ 
                   12021:       case 11:
                   12022:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12023:          if (num_filled != 8) {
                   12024:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12025:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12026:            goto end;
                   12027:          }
                   12028:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12029:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12030:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12031:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12032:          /* day and month of proj2 are not used but only year anproj2.*/
1.273   ! brouard  12033:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
        !          12034:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
        !          12035: 
1.258     brouard  12036:        }
1.254     brouard  12037:        break;
1.258     brouard  12038:       case 12:
                   12039:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12040:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12041:          if (num_filled != 8) {
1.262     brouard  12042:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12043:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12044:            goto end;
                   12045:          }
                   12046:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12047:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12048:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12049:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12050:          /* day and month of proj2 are not used but only year anproj2.*/
1.273   ! brouard  12051:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
        !          12052:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12053:        }
1.230     brouard  12054:        break;
1.258     brouard  12055:       case 13:
                   12056:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12057:          if (num_filled == 0){
                   12058:            resultline[0]='\0';
                   12059:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12060:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12061:            break;
                   12062:          } else if (num_filled != 1){
                   12063:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12064:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12065:          }
                   12066:          nresult++; /* Sum of resultlines */
                   12067:          printf("Result %d: result=%s\n",nresult, resultline);
                   12068:          if(nresult > MAXRESULTLINES){
                   12069:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12070:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12071:            goto end;
                   12072:          }
                   12073:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12074:          fprintf(ficparo,"result: %s\n",resultline);
                   12075:          fprintf(ficres,"result: %s\n",resultline);
                   12076:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12077:          break;
1.258     brouard  12078:        case 14: 
1.259     brouard  12079:          if(ncovmodel >2 && nresult==0 ){
                   12080:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12081:            goto end;
                   12082:          }
1.259     brouard  12083:          break;
1.258     brouard  12084:        default:
                   12085:          nresult=1;
                   12086:          decoderesult(".",nresult ); /* No covariate */
                   12087:        }
                   12088:       } /* End switch parameterline */
                   12089:     }while(endishere==0); /* End do */
1.126     brouard  12090:     
1.230     brouard  12091:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12092:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12093:     
                   12094:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12095:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12096:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12097: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12098: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12099:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12100: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12101: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12102:     }else{
1.270     brouard  12103:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12104:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12105:     }
                   12106:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12107:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273   ! brouard  12108:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12109:                
1.225     brouard  12110:     /*------------ free_vector  -------------*/
                   12111:     /*  chdir(path); */
1.220     brouard  12112:                
1.215     brouard  12113:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12114:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12115:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12116:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12117:     free_lvector(num,1,n);
                   12118:     free_vector(agedc,1,n);
                   12119:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12120:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12121:     fclose(ficparo);
                   12122:     fclose(ficres);
1.220     brouard  12123:                
                   12124:                
1.186     brouard  12125:     /* Other results (useful)*/
1.220     brouard  12126:                
                   12127:                
1.126     brouard  12128:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12129:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12130:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12131:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12132:     fclose(ficrespl);
                   12133: 
                   12134:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12135:     /*#include "hpijx.h"*/
                   12136:     hPijx(p, bage, fage);
1.145     brouard  12137:     fclose(ficrespij);
1.227     brouard  12138:     
1.220     brouard  12139:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12140:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12141:     k=1;
1.126     brouard  12142:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12143:     
1.269     brouard  12144:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12145:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12146:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12147:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12148:        for(k=1;k<=ncovcombmax;k++)
                   12149:          probs[i][j][k]=0.;
1.269     brouard  12150:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12151:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12152:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12153:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12154:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12155:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12156:          for(k=1;k<=ncovcombmax;k++)
                   12157:            mobaverages[i][j][k]=0.;
1.219     brouard  12158:       mobaverage=mobaverages;
                   12159:       if (mobilav!=0) {
1.235     brouard  12160:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12161:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12162:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12163:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12164:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12165:        }
1.269     brouard  12166:       } else if (mobilavproj !=0) {
1.235     brouard  12167:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12168:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12169:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12170:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12171:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12172:        }
1.269     brouard  12173:       }else{
                   12174:        printf("Internal error moving average\n");
                   12175:        fflush(stdout);
                   12176:        exit(1);
1.219     brouard  12177:       }
                   12178:     }/* end if moving average */
1.227     brouard  12179:     
1.126     brouard  12180:     /*---------- Forecasting ------------------*/
                   12181:     if(prevfcast==1){
                   12182:       /*    if(stepm ==1){*/
1.269     brouard  12183:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12184:     }
1.269     brouard  12185: 
                   12186:     /* Backcasting */
1.217     brouard  12187:     if(backcast==1){
1.219     brouard  12188:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12189:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12190:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12191: 
                   12192:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12193: 
                   12194:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12195: 
1.219     brouard  12196:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12197:       fclose(ficresplb);
                   12198: 
1.222     brouard  12199:       hBijx(p, bage, fage, mobaverage);
                   12200:       fclose(ficrespijb);
1.219     brouard  12201: 
1.269     brouard  12202:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12203:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12204:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12205: 
                   12206:       
1.269     brouard  12207:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12208:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12209:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12210:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12211:     }    /* end  Backcasting */
1.268     brouard  12212:  
1.186     brouard  12213:  
                   12214:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12215: 
1.215     brouard  12216:     free_ivector(wav,1,imx);
                   12217:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12218:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12219:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12220:                
                   12221:                
1.127     brouard  12222:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12223:                
1.201     brouard  12224:     strcpy(filerese,"E_");
                   12225:     strcat(filerese,fileresu);
1.126     brouard  12226:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12227:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12228:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12229:     }
1.208     brouard  12230:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12231:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12232: 
                   12233:     pstamp(ficreseij);
1.219     brouard  12234:                
1.235     brouard  12235:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12236:     if (cptcovn < 1){i1=1;}
                   12237:     
                   12238:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12239:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12240:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12241:        continue;
1.219     brouard  12242:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12243:       printf("\n#****** ");
1.225     brouard  12244:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12245:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12246:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12247:       }
                   12248:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12249:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12250:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12251:       }
                   12252:       fprintf(ficreseij,"******\n");
1.235     brouard  12253:       printf("******\n");
1.219     brouard  12254:       
                   12255:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12256:       oldm=oldms;savm=savms;
1.235     brouard  12257:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12258:       
1.219     brouard  12259:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12260:     }
                   12261:     fclose(ficreseij);
1.208     brouard  12262:     printf("done evsij\n");fflush(stdout);
                   12263:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12264: 
1.218     brouard  12265:                
1.227     brouard  12266:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12267:                
1.201     brouard  12268:     strcpy(filerest,"T_");
                   12269:     strcat(filerest,fileresu);
1.127     brouard  12270:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12271:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12272:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12273:     }
1.208     brouard  12274:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12275:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12276:     strcpy(fileresstde,"STDE_");
                   12277:     strcat(fileresstde,fileresu);
1.126     brouard  12278:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12279:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12280:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12281:     }
1.227     brouard  12282:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12283:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12284: 
1.201     brouard  12285:     strcpy(filerescve,"CVE_");
                   12286:     strcat(filerescve,fileresu);
1.126     brouard  12287:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12288:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12289:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12290:     }
1.227     brouard  12291:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12292:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12293: 
1.201     brouard  12294:     strcpy(fileresv,"V_");
                   12295:     strcat(fileresv,fileresu);
1.126     brouard  12296:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12297:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12298:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12299:     }
1.227     brouard  12300:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12301:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12302: 
1.235     brouard  12303:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12304:     if (cptcovn < 1){i1=1;}
                   12305:     
                   12306:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12307:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12308:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12309:        continue;
1.242     brouard  12310:       printf("\n#****** Result for:");
                   12311:       fprintf(ficrest,"\n#****** Result for:");
                   12312:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12313:       for(j=1;j<=cptcoveff;j++){ 
                   12314:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12315:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12316:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12317:       }
1.235     brouard  12318:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12319:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12320:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12321:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12322:       }        
1.208     brouard  12323:       fprintf(ficrest,"******\n");
1.227     brouard  12324:       fprintf(ficlog,"******\n");
                   12325:       printf("******\n");
1.208     brouard  12326:       
                   12327:       fprintf(ficresstdeij,"\n#****** ");
                   12328:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12329:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12330:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12331:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12332:       }
1.235     brouard  12333:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12334:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12335:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12336:       }        
1.208     brouard  12337:       fprintf(ficresstdeij,"******\n");
                   12338:       fprintf(ficrescveij,"******\n");
                   12339:       
                   12340:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12341:       /* pstamp(ficresvij); */
1.225     brouard  12342:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12343:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12344:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12345:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12346:       }        
1.208     brouard  12347:       fprintf(ficresvij,"******\n");
                   12348:       
                   12349:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12350:       oldm=oldms;savm=savms;
1.235     brouard  12351:       printf(" cvevsij ");
                   12352:       fprintf(ficlog, " cvevsij ");
                   12353:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12354:       printf(" end cvevsij \n ");
                   12355:       fprintf(ficlog, " end cvevsij \n ");
                   12356:       
                   12357:       /*
                   12358:        */
                   12359:       /* goto endfree; */
                   12360:       
                   12361:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12362:       pstamp(ficrest);
                   12363:       
1.269     brouard  12364:       epj=vector(1,nlstate+1);
1.208     brouard  12365:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12366:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12367:        cptcod= 0; /* To be deleted */
                   12368:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12369:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12370:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12371:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12372:        if(vpopbased==1)
                   12373:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12374:        else
                   12375:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12376:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12377:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12378:        fprintf(ficrest,"\n");
                   12379:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12380:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12381:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12382:        for(age=bage; age <=fage ;age++){
1.235     brouard  12383:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12384:          if (vpopbased==1) {
                   12385:            if(mobilav ==0){
                   12386:              for(i=1; i<=nlstate;i++)
                   12387:                prlim[i][i]=probs[(int)age][i][k];
                   12388:            }else{ /* mobilav */ 
                   12389:              for(i=1; i<=nlstate;i++)
                   12390:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12391:            }
                   12392:          }
1.219     brouard  12393:          
1.227     brouard  12394:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12395:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12396:          /* printf(" age %4.0f ",age); */
                   12397:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12398:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12399:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12400:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12401:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12402:            }
                   12403:            epj[nlstate+1] +=epj[j];
                   12404:          }
                   12405:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12406:          
1.227     brouard  12407:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12408:            for(j=1;j <=nlstate;j++)
                   12409:              vepp += vareij[i][j][(int)age];
                   12410:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12411:          for(j=1;j <=nlstate;j++){
                   12412:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12413:          }
                   12414:          fprintf(ficrest,"\n");
                   12415:        }
1.208     brouard  12416:       } /* End vpopbased */
1.269     brouard  12417:       free_vector(epj,1,nlstate+1);
1.208     brouard  12418:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12419:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12420:       printf("done selection\n");fflush(stdout);
                   12421:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12422:       
1.235     brouard  12423:     } /* End k selection */
1.227     brouard  12424: 
                   12425:     printf("done State-specific expectancies\n");fflush(stdout);
                   12426:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12427: 
1.269     brouard  12428:     /* variance-covariance of period prevalence*/
                   12429:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12430: 
1.227     brouard  12431:     
                   12432:     free_vector(weight,1,n);
                   12433:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12434:     free_imatrix(s,1,maxwav+1,1,n);
                   12435:     free_matrix(anint,1,maxwav,1,n); 
                   12436:     free_matrix(mint,1,maxwav,1,n);
                   12437:     free_ivector(cod,1,n);
                   12438:     free_ivector(tab,1,NCOVMAX);
                   12439:     fclose(ficresstdeij);
                   12440:     fclose(ficrescveij);
                   12441:     fclose(ficresvij);
                   12442:     fclose(ficrest);
                   12443:     fclose(ficpar);
                   12444:     
                   12445:     
1.126     brouard  12446:     /*---------- End : free ----------------*/
1.219     brouard  12447:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12448:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12449:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12450:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12451:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12452:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12453:   /* endfree:*/
                   12454:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12455:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12456:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12457:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12458:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12459:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12460:   free_matrix(covar,0,NCOVMAX,1,n);
                   12461:   free_matrix(matcov,1,npar,1,npar);
                   12462:   free_matrix(hess,1,npar,1,npar);
                   12463:   /*free_vector(delti,1,npar);*/
                   12464:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12465:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12466:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12467:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12468:   
                   12469:   free_ivector(ncodemax,1,NCOVMAX);
                   12470:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12471:   free_ivector(Dummy,-1,NCOVMAX);
                   12472:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12473:   free_ivector(DummyV,1,NCOVMAX);
                   12474:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12475:   free_ivector(Typevar,-1,NCOVMAX);
                   12476:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12477:   free_ivector(TvarsQ,1,NCOVMAX);
                   12478:   free_ivector(TvarsQind,1,NCOVMAX);
                   12479:   free_ivector(TvarsD,1,NCOVMAX);
                   12480:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12481:   free_ivector(TvarFD,1,NCOVMAX);
                   12482:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12483:   free_ivector(TvarF,1,NCOVMAX);
                   12484:   free_ivector(TvarFind,1,NCOVMAX);
                   12485:   free_ivector(TvarV,1,NCOVMAX);
                   12486:   free_ivector(TvarVind,1,NCOVMAX);
                   12487:   free_ivector(TvarA,1,NCOVMAX);
                   12488:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12489:   free_ivector(TvarFQ,1,NCOVMAX);
                   12490:   free_ivector(TvarFQind,1,NCOVMAX);
                   12491:   free_ivector(TvarVD,1,NCOVMAX);
                   12492:   free_ivector(TvarVDind,1,NCOVMAX);
                   12493:   free_ivector(TvarVQ,1,NCOVMAX);
                   12494:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12495:   free_ivector(Tvarsel,1,NCOVMAX);
                   12496:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12497:   free_ivector(Tposprod,1,NCOVMAX);
                   12498:   free_ivector(Tprod,1,NCOVMAX);
                   12499:   free_ivector(Tvaraff,1,NCOVMAX);
                   12500:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12501:   free_ivector(Tage,1,NCOVMAX);
                   12502:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12503:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12504:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12505:   
                   12506:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12507:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12508:   fflush(fichtm);
                   12509:   fflush(ficgp);
                   12510:   
1.227     brouard  12511:   
1.126     brouard  12512:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12513:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12514:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12515:   }else{
                   12516:     printf("End of Imach\n");
                   12517:     fprintf(ficlog,"End of Imach\n");
                   12518:   }
                   12519:   printf("See log file on %s\n",filelog);
                   12520:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12521:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12522:   rend_time = time(NULL);  
                   12523:   end_time = *localtime(&rend_time);
                   12524:   /* tml = *localtime(&end_time.tm_sec); */
                   12525:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12526:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12527:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12528:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12529:   
1.157     brouard  12530:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12531:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12532:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12533:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12534: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12535:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12536:   fclose(fichtm);
                   12537:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12538:   fclose(fichtmcov);
                   12539:   fclose(ficgp);
                   12540:   fclose(ficlog);
                   12541:   /*------ End -----------*/
1.227     brouard  12542:   
                   12543:   
                   12544:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12545: #ifdef WIN32
1.227     brouard  12546:   if (_chdir(pathcd) != 0)
                   12547:     printf("Can't move to directory %s!\n",path);
                   12548:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12549: #else
1.227     brouard  12550:     if(chdir(pathcd) != 0)
                   12551:       printf("Can't move to directory %s!\n", path);
                   12552:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12553: #endif 
1.126     brouard  12554:     printf("Current directory %s!\n",pathcd);
                   12555:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12556:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12557: #ifdef _WIN32
1.126     brouard  12558:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12559: #endif
                   12560:   if(!stat(plotcmd,&info)){
1.158     brouard  12561:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12562:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12563:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12564:     }else
                   12565:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12566: #ifdef __unix
1.126     brouard  12567:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12568:     if(!stat(plotcmd,&info)){
1.158     brouard  12569:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12570:     }else
                   12571:       strcpy(pplotcmd,plotcmd);
                   12572: #endif
                   12573:   }else
                   12574:     strcpy(pplotcmd,plotcmd);
                   12575:   
                   12576:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12577:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12578:   
1.126     brouard  12579:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12580:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12581:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12582:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12583:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12584:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12585:   }
1.158     brouard  12586:   printf(" Successful, please wait...");
1.126     brouard  12587:   while (z[0] != 'q') {
                   12588:     /* chdir(path); */
1.154     brouard  12589:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12590:     scanf("%s",z);
                   12591: /*     if (z[0] == 'c') system("./imach"); */
                   12592:     if (z[0] == 'e') {
1.158     brouard  12593: #ifdef __APPLE__
1.152     brouard  12594:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12595: #elif __linux
                   12596:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12597: #else
1.152     brouard  12598:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12599: #endif
                   12600:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12601:       system(pplotcmd);
1.126     brouard  12602:     }
                   12603:     else if (z[0] == 'g') system(plotcmd);
                   12604:     else if (z[0] == 'q') exit(0);
                   12605:   }
1.227     brouard  12606: end:
1.126     brouard  12607:   while (z[0] != 'q') {
1.195     brouard  12608:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12609:     scanf("%s",z);
                   12610:   }
                   12611: }

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