Annotation of imach/src/imach.c, revision 1.286

1.286   ! brouard     1: /* $Id: imach.c,v 1.285 2018/04/21 21:02:16 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.286   ! brouard     4:   Revision 1.285  2018/04/21 21:02:16  brouard
        !             5:   Summary: Some bugs fixed, valgrind tested
        !             6: 
1.285     brouard     7:   Revision 1.284  2018/04/20 05:22:13  brouard
                      8:   Summary: Computing mean and stdeviation of fixed quantitative variables
                      9: 
1.284     brouard    10:   Revision 1.283  2018/04/19 14:49:16  brouard
                     11:   Summary: Some minor bugs fixed
                     12: 
1.283     brouard    13:   Revision 1.282  2018/02/27 22:50:02  brouard
                     14:   *** empty log message ***
                     15: 
1.282     brouard    16:   Revision 1.281  2018/02/27 19:25:23  brouard
                     17:   Summary: Adding second argument for quitting
                     18: 
1.281     brouard    19:   Revision 1.280  2018/02/21 07:58:13  brouard
                     20:   Summary: 0.99r15
                     21: 
                     22:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     23: 
1.280     brouard    24:   Revision 1.279  2017/07/20 13:35:01  brouard
                     25:   Summary: temporary working
                     26: 
1.279     brouard    27:   Revision 1.278  2017/07/19 14:09:02  brouard
                     28:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     29: 
1.278     brouard    30:   Revision 1.277  2017/07/17 08:53:49  brouard
                     31:   Summary: BOM files can be read now
                     32: 
1.277     brouard    33:   Revision 1.276  2017/06/30 15:48:31  brouard
                     34:   Summary: Graphs improvements
                     35: 
1.276     brouard    36:   Revision 1.275  2017/06/30 13:39:33  brouard
                     37:   Summary: Saito's color
                     38: 
1.275     brouard    39:   Revision 1.274  2017/06/29 09:47:08  brouard
                     40:   Summary: Version 0.99r14
                     41: 
1.274     brouard    42:   Revision 1.273  2017/06/27 11:06:02  brouard
                     43:   Summary: More documentation on projections
                     44: 
1.273     brouard    45:   Revision 1.272  2017/06/27 10:22:40  brouard
                     46:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     47: 
1.272     brouard    48:   Revision 1.271  2017/06/27 10:17:50  brouard
                     49:   Summary: Some bug with rint
                     50: 
1.271     brouard    51:   Revision 1.270  2017/05/24 05:45:29  brouard
                     52:   *** empty log message ***
                     53: 
1.270     brouard    54:   Revision 1.269  2017/05/23 08:39:25  brouard
                     55:   Summary: Code into subroutine, cleanings
                     56: 
1.269     brouard    57:   Revision 1.268  2017/05/18 20:09:32  brouard
                     58:   Summary: backprojection and confidence intervals of backprevalence
                     59: 
1.268     brouard    60:   Revision 1.267  2017/05/13 10:25:05  brouard
                     61:   Summary: temporary save for backprojection
                     62: 
1.267     brouard    63:   Revision 1.266  2017/05/13 07:26:12  brouard
                     64:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     65: 
1.266     brouard    66:   Revision 1.265  2017/04/26 16:22:11  brouard
                     67:   Summary: imach 0.99r13 Some bugs fixed
                     68: 
1.265     brouard    69:   Revision 1.264  2017/04/26 06:01:29  brouard
                     70:   Summary: Labels in graphs
                     71: 
1.264     brouard    72:   Revision 1.263  2017/04/24 15:23:15  brouard
                     73:   Summary: to save
                     74: 
1.263     brouard    75:   Revision 1.262  2017/04/18 16:48:12  brouard
                     76:   *** empty log message ***
                     77: 
1.262     brouard    78:   Revision 1.261  2017/04/05 10:14:09  brouard
                     79:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     80: 
1.261     brouard    81:   Revision 1.260  2017/04/04 17:46:59  brouard
                     82:   Summary: Gnuplot indexations fixed (humm)
                     83: 
1.260     brouard    84:   Revision 1.259  2017/04/04 13:01:16  brouard
                     85:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     86: 
1.259     brouard    87:   Revision 1.258  2017/04/03 10:17:47  brouard
                     88:   Summary: Version 0.99r12
                     89: 
                     90:   Some cleanings, conformed with updated documentation.
                     91: 
1.258     brouard    92:   Revision 1.257  2017/03/29 16:53:30  brouard
                     93:   Summary: Temp
                     94: 
1.257     brouard    95:   Revision 1.256  2017/03/27 05:50:23  brouard
                     96:   Summary: Temporary
                     97: 
1.256     brouard    98:   Revision 1.255  2017/03/08 16:02:28  brouard
                     99:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    100: 
1.255     brouard   101:   Revision 1.254  2017/03/08 07:13:00  brouard
                    102:   Summary: Fixing data parameter line
                    103: 
1.254     brouard   104:   Revision 1.253  2016/12/15 11:59:41  brouard
                    105:   Summary: 0.99 in progress
                    106: 
1.253     brouard   107:   Revision 1.252  2016/09/15 21:15:37  brouard
                    108:   *** empty log message ***
                    109: 
1.252     brouard   110:   Revision 1.251  2016/09/15 15:01:13  brouard
                    111:   Summary: not working
                    112: 
1.251     brouard   113:   Revision 1.250  2016/09/08 16:07:27  brouard
                    114:   Summary: continue
                    115: 
1.250     brouard   116:   Revision 1.249  2016/09/07 17:14:18  brouard
                    117:   Summary: Starting values from frequencies
                    118: 
1.249     brouard   119:   Revision 1.248  2016/09/07 14:10:18  brouard
                    120:   *** empty log message ***
                    121: 
1.248     brouard   122:   Revision 1.247  2016/09/02 11:11:21  brouard
                    123:   *** empty log message ***
                    124: 
1.247     brouard   125:   Revision 1.246  2016/09/02 08:49:22  brouard
                    126:   *** empty log message ***
                    127: 
1.246     brouard   128:   Revision 1.245  2016/09/02 07:25:01  brouard
                    129:   *** empty log message ***
                    130: 
1.245     brouard   131:   Revision 1.244  2016/09/02 07:17:34  brouard
                    132:   *** empty log message ***
                    133: 
1.244     brouard   134:   Revision 1.243  2016/09/02 06:45:35  brouard
                    135:   *** empty log message ***
                    136: 
1.243     brouard   137:   Revision 1.242  2016/08/30 15:01:20  brouard
                    138:   Summary: Fixing a lots
                    139: 
1.242     brouard   140:   Revision 1.241  2016/08/29 17:17:25  brouard
                    141:   Summary: gnuplot problem in Back projection to fix
                    142: 
1.241     brouard   143:   Revision 1.240  2016/08/29 07:53:18  brouard
                    144:   Summary: Better
                    145: 
1.240     brouard   146:   Revision 1.239  2016/08/26 15:51:03  brouard
                    147:   Summary: Improvement in Powell output in order to copy and paste
                    148: 
                    149:   Author:
                    150: 
1.239     brouard   151:   Revision 1.238  2016/08/26 14:23:35  brouard
                    152:   Summary: Starting tests of 0.99
                    153: 
1.238     brouard   154:   Revision 1.237  2016/08/26 09:20:19  brouard
                    155:   Summary: to valgrind
                    156: 
1.237     brouard   157:   Revision 1.236  2016/08/25 10:50:18  brouard
                    158:   *** empty log message ***
                    159: 
1.236     brouard   160:   Revision 1.235  2016/08/25 06:59:23  brouard
                    161:   *** empty log message ***
                    162: 
1.235     brouard   163:   Revision 1.234  2016/08/23 16:51:20  brouard
                    164:   *** empty log message ***
                    165: 
1.234     brouard   166:   Revision 1.233  2016/08/23 07:40:50  brouard
                    167:   Summary: not working
                    168: 
1.233     brouard   169:   Revision 1.232  2016/08/22 14:20:21  brouard
                    170:   Summary: not working
                    171: 
1.232     brouard   172:   Revision 1.231  2016/08/22 07:17:15  brouard
                    173:   Summary: not working
                    174: 
1.231     brouard   175:   Revision 1.230  2016/08/22 06:55:53  brouard
                    176:   Summary: Not working
                    177: 
1.230     brouard   178:   Revision 1.229  2016/07/23 09:45:53  brouard
                    179:   Summary: Completing for func too
                    180: 
1.229     brouard   181:   Revision 1.228  2016/07/22 17:45:30  brouard
                    182:   Summary: Fixing some arrays, still debugging
                    183: 
1.227     brouard   184:   Revision 1.226  2016/07/12 18:42:34  brouard
                    185:   Summary: temp
                    186: 
1.226     brouard   187:   Revision 1.225  2016/07/12 08:40:03  brouard
                    188:   Summary: saving but not running
                    189: 
1.225     brouard   190:   Revision 1.224  2016/07/01 13:16:01  brouard
                    191:   Summary: Fixes
                    192: 
1.224     brouard   193:   Revision 1.223  2016/02/19 09:23:35  brouard
                    194:   Summary: temporary
                    195: 
1.223     brouard   196:   Revision 1.222  2016/02/17 08:14:50  brouard
                    197:   Summary: Probably last 0.98 stable version 0.98r6
                    198: 
1.222     brouard   199:   Revision 1.221  2016/02/15 23:35:36  brouard
                    200:   Summary: minor bug
                    201: 
1.220     brouard   202:   Revision 1.219  2016/02/15 00:48:12  brouard
                    203:   *** empty log message ***
                    204: 
1.219     brouard   205:   Revision 1.218  2016/02/12 11:29:23  brouard
                    206:   Summary: 0.99 Back projections
                    207: 
1.218     brouard   208:   Revision 1.217  2015/12/23 17:18:31  brouard
                    209:   Summary: Experimental backcast
                    210: 
1.217     brouard   211:   Revision 1.216  2015/12/18 17:32:11  brouard
                    212:   Summary: 0.98r4 Warning and status=-2
                    213: 
                    214:   Version 0.98r4 is now:
                    215:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    216:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    217:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    218: 
1.216     brouard   219:   Revision 1.215  2015/12/16 08:52:24  brouard
                    220:   Summary: 0.98r4 working
                    221: 
1.215     brouard   222:   Revision 1.214  2015/12/16 06:57:54  brouard
                    223:   Summary: temporary not working
                    224: 
1.214     brouard   225:   Revision 1.213  2015/12/11 18:22:17  brouard
                    226:   Summary: 0.98r4
                    227: 
1.213     brouard   228:   Revision 1.212  2015/11/21 12:47:24  brouard
                    229:   Summary: minor typo
                    230: 
1.212     brouard   231:   Revision 1.211  2015/11/21 12:41:11  brouard
                    232:   Summary: 0.98r3 with some graph of projected cross-sectional
                    233: 
                    234:   Author: Nicolas Brouard
                    235: 
1.211     brouard   236:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   237:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   238:   Summary: Adding ftolpl parameter
                    239:   Author: N Brouard
                    240: 
                    241:   We had difficulties to get smoothed confidence intervals. It was due
                    242:   to the period prevalence which wasn't computed accurately. The inner
                    243:   parameter ftolpl is now an outer parameter of the .imach parameter
                    244:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    245:   computation are long.
                    246: 
1.209     brouard   247:   Revision 1.208  2015/11/17 14:31:57  brouard
                    248:   Summary: temporary
                    249: 
1.208     brouard   250:   Revision 1.207  2015/10/27 17:36:57  brouard
                    251:   *** empty log message ***
                    252: 
1.207     brouard   253:   Revision 1.206  2015/10/24 07:14:11  brouard
                    254:   *** empty log message ***
                    255: 
1.206     brouard   256:   Revision 1.205  2015/10/23 15:50:53  brouard
                    257:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    258: 
1.205     brouard   259:   Revision 1.204  2015/10/01 16:20:26  brouard
                    260:   Summary: Some new graphs of contribution to likelihood
                    261: 
1.204     brouard   262:   Revision 1.203  2015/09/30 17:45:14  brouard
                    263:   Summary: looking at better estimation of the hessian
                    264: 
                    265:   Also a better criteria for convergence to the period prevalence And
                    266:   therefore adding the number of years needed to converge. (The
                    267:   prevalence in any alive state shold sum to one
                    268: 
1.203     brouard   269:   Revision 1.202  2015/09/22 19:45:16  brouard
                    270:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    271: 
1.202     brouard   272:   Revision 1.201  2015/09/15 17:34:58  brouard
                    273:   Summary: 0.98r0
                    274: 
                    275:   - Some new graphs like suvival functions
                    276:   - Some bugs fixed like model=1+age+V2.
                    277: 
1.201     brouard   278:   Revision 1.200  2015/09/09 16:53:55  brouard
                    279:   Summary: Big bug thanks to Flavia
                    280: 
                    281:   Even model=1+age+V2. did not work anymore
                    282: 
1.200     brouard   283:   Revision 1.199  2015/09/07 14:09:23  brouard
                    284:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    285: 
1.199     brouard   286:   Revision 1.198  2015/09/03 07:14:39  brouard
                    287:   Summary: 0.98q5 Flavia
                    288: 
1.198     brouard   289:   Revision 1.197  2015/09/01 18:24:39  brouard
                    290:   *** empty log message ***
                    291: 
1.197     brouard   292:   Revision 1.196  2015/08/18 23:17:52  brouard
                    293:   Summary: 0.98q5
                    294: 
1.196     brouard   295:   Revision 1.195  2015/08/18 16:28:39  brouard
                    296:   Summary: Adding a hack for testing purpose
                    297: 
                    298:   After reading the title, ftol and model lines, if the comment line has
                    299:   a q, starting with #q, the answer at the end of the run is quit. It
                    300:   permits to run test files in batch with ctest. The former workaround was
                    301:   $ echo q | imach foo.imach
                    302: 
1.195     brouard   303:   Revision 1.194  2015/08/18 13:32:00  brouard
                    304:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    305: 
1.194     brouard   306:   Revision 1.193  2015/08/04 07:17:42  brouard
                    307:   Summary: 0.98q4
                    308: 
1.193     brouard   309:   Revision 1.192  2015/07/16 16:49:02  brouard
                    310:   Summary: Fixing some outputs
                    311: 
1.192     brouard   312:   Revision 1.191  2015/07/14 10:00:33  brouard
                    313:   Summary: Some fixes
                    314: 
1.191     brouard   315:   Revision 1.190  2015/05/05 08:51:13  brouard
                    316:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    317: 
                    318:   Fix 1+age+.
                    319: 
1.190     brouard   320:   Revision 1.189  2015/04/30 14:45:16  brouard
                    321:   Summary: 0.98q2
                    322: 
1.189     brouard   323:   Revision 1.188  2015/04/30 08:27:53  brouard
                    324:   *** empty log message ***
                    325: 
1.188     brouard   326:   Revision 1.187  2015/04/29 09:11:15  brouard
                    327:   *** empty log message ***
                    328: 
1.187     brouard   329:   Revision 1.186  2015/04/23 12:01:52  brouard
                    330:   Summary: V1*age is working now, version 0.98q1
                    331: 
                    332:   Some codes had been disabled in order to simplify and Vn*age was
                    333:   working in the optimization phase, ie, giving correct MLE parameters,
                    334:   but, as usual, outputs were not correct and program core dumped.
                    335: 
1.186     brouard   336:   Revision 1.185  2015/03/11 13:26:42  brouard
                    337:   Summary: Inclusion of compile and links command line for Intel Compiler
                    338: 
1.185     brouard   339:   Revision 1.184  2015/03/11 11:52:39  brouard
                    340:   Summary: Back from Windows 8. Intel Compiler
                    341: 
1.184     brouard   342:   Revision 1.183  2015/03/10 20:34:32  brouard
                    343:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    344: 
                    345:   We use directest instead of original Powell test; probably no
                    346:   incidence on the results, but better justifications;
                    347:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    348:   wrong results.
                    349: 
1.183     brouard   350:   Revision 1.182  2015/02/12 08:19:57  brouard
                    351:   Summary: Trying to keep directest which seems simpler and more general
                    352:   Author: Nicolas Brouard
                    353: 
1.182     brouard   354:   Revision 1.181  2015/02/11 23:22:24  brouard
                    355:   Summary: Comments on Powell added
                    356: 
                    357:   Author:
                    358: 
1.181     brouard   359:   Revision 1.180  2015/02/11 17:33:45  brouard
                    360:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    361: 
1.180     brouard   362:   Revision 1.179  2015/01/04 09:57:06  brouard
                    363:   Summary: back to OS/X
                    364: 
1.179     brouard   365:   Revision 1.178  2015/01/04 09:35:48  brouard
                    366:   *** empty log message ***
                    367: 
1.178     brouard   368:   Revision 1.177  2015/01/03 18:40:56  brouard
                    369:   Summary: Still testing ilc32 on OSX
                    370: 
1.177     brouard   371:   Revision 1.176  2015/01/03 16:45:04  brouard
                    372:   *** empty log message ***
                    373: 
1.176     brouard   374:   Revision 1.175  2015/01/03 16:33:42  brouard
                    375:   *** empty log message ***
                    376: 
1.175     brouard   377:   Revision 1.174  2015/01/03 16:15:49  brouard
                    378:   Summary: Still in cross-compilation
                    379: 
1.174     brouard   380:   Revision 1.173  2015/01/03 12:06:26  brouard
                    381:   Summary: trying to detect cross-compilation
                    382: 
1.173     brouard   383:   Revision 1.172  2014/12/27 12:07:47  brouard
                    384:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    385: 
1.172     brouard   386:   Revision 1.171  2014/12/23 13:26:59  brouard
                    387:   Summary: Back from Visual C
                    388: 
                    389:   Still problem with utsname.h on Windows
                    390: 
1.171     brouard   391:   Revision 1.170  2014/12/23 11:17:12  brouard
                    392:   Summary: Cleaning some \%% back to %%
                    393: 
                    394:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    395: 
1.170     brouard   396:   Revision 1.169  2014/12/22 23:08:31  brouard
                    397:   Summary: 0.98p
                    398: 
                    399:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    400: 
1.169     brouard   401:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   402:   Summary: update
1.169     brouard   403: 
1.168     brouard   404:   Revision 1.167  2014/12/22 13:50:56  brouard
                    405:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    406: 
                    407:   Testing on Linux 64
                    408: 
1.167     brouard   409:   Revision 1.166  2014/12/22 11:40:47  brouard
                    410:   *** empty log message ***
                    411: 
1.166     brouard   412:   Revision 1.165  2014/12/16 11:20:36  brouard
                    413:   Summary: After compiling on Visual C
                    414: 
                    415:   * imach.c (Module): Merging 1.61 to 1.162
                    416: 
1.165     brouard   417:   Revision 1.164  2014/12/16 10:52:11  brouard
                    418:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    419: 
                    420:   * imach.c (Module): Merging 1.61 to 1.162
                    421: 
1.164     brouard   422:   Revision 1.163  2014/12/16 10:30:11  brouard
                    423:   * imach.c (Module): Merging 1.61 to 1.162
                    424: 
1.163     brouard   425:   Revision 1.162  2014/09/25 11:43:39  brouard
                    426:   Summary: temporary backup 0.99!
                    427: 
1.162     brouard   428:   Revision 1.1  2014/09/16 11:06:58  brouard
                    429:   Summary: With some code (wrong) for nlopt
                    430: 
                    431:   Author:
                    432: 
                    433:   Revision 1.161  2014/09/15 20:41:41  brouard
                    434:   Summary: Problem with macro SQR on Intel compiler
                    435: 
1.161     brouard   436:   Revision 1.160  2014/09/02 09:24:05  brouard
                    437:   *** empty log message ***
                    438: 
1.160     brouard   439:   Revision 1.159  2014/09/01 10:34:10  brouard
                    440:   Summary: WIN32
                    441:   Author: Brouard
                    442: 
1.159     brouard   443:   Revision 1.158  2014/08/27 17:11:51  brouard
                    444:   *** empty log message ***
                    445: 
1.158     brouard   446:   Revision 1.157  2014/08/27 16:26:55  brouard
                    447:   Summary: Preparing windows Visual studio version
                    448:   Author: Brouard
                    449: 
                    450:   In order to compile on Visual studio, time.h is now correct and time_t
                    451:   and tm struct should be used. difftime should be used but sometimes I
                    452:   just make the differences in raw time format (time(&now).
                    453:   Trying to suppress #ifdef LINUX
                    454:   Add xdg-open for __linux in order to open default browser.
                    455: 
1.157     brouard   456:   Revision 1.156  2014/08/25 20:10:10  brouard
                    457:   *** empty log message ***
                    458: 
1.156     brouard   459:   Revision 1.155  2014/08/25 18:32:34  brouard
                    460:   Summary: New compile, minor changes
                    461:   Author: Brouard
                    462: 
1.155     brouard   463:   Revision 1.154  2014/06/20 17:32:08  brouard
                    464:   Summary: Outputs now all graphs of convergence to period prevalence
                    465: 
1.154     brouard   466:   Revision 1.153  2014/06/20 16:45:46  brouard
                    467:   Summary: If 3 live state, convergence to period prevalence on same graph
                    468:   Author: Brouard
                    469: 
1.153     brouard   470:   Revision 1.152  2014/06/18 17:54:09  brouard
                    471:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    472: 
1.152     brouard   473:   Revision 1.151  2014/06/18 16:43:30  brouard
                    474:   *** empty log message ***
                    475: 
1.151     brouard   476:   Revision 1.150  2014/06/18 16:42:35  brouard
                    477:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    478:   Author: brouard
                    479: 
1.150     brouard   480:   Revision 1.149  2014/06/18 15:51:14  brouard
                    481:   Summary: Some fixes in parameter files errors
                    482:   Author: Nicolas Brouard
                    483: 
1.149     brouard   484:   Revision 1.148  2014/06/17 17:38:48  brouard
                    485:   Summary: Nothing new
                    486:   Author: Brouard
                    487: 
                    488:   Just a new packaging for OS/X version 0.98nS
                    489: 
1.148     brouard   490:   Revision 1.147  2014/06/16 10:33:11  brouard
                    491:   *** empty log message ***
                    492: 
1.147     brouard   493:   Revision 1.146  2014/06/16 10:20:28  brouard
                    494:   Summary: Merge
                    495:   Author: Brouard
                    496: 
                    497:   Merge, before building revised version.
                    498: 
1.146     brouard   499:   Revision 1.145  2014/06/10 21:23:15  brouard
                    500:   Summary: Debugging with valgrind
                    501:   Author: Nicolas Brouard
                    502: 
                    503:   Lot of changes in order to output the results with some covariates
                    504:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    505:   improve the code.
                    506:   No more memory valgrind error but a lot has to be done in order to
                    507:   continue the work of splitting the code into subroutines.
                    508:   Also, decodemodel has been improved. Tricode is still not
                    509:   optimal. nbcode should be improved. Documentation has been added in
                    510:   the source code.
                    511: 
1.144     brouard   512:   Revision 1.143  2014/01/26 09:45:38  brouard
                    513:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    514: 
                    515:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    516:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    517: 
1.143     brouard   518:   Revision 1.142  2014/01/26 03:57:36  brouard
                    519:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    520: 
                    521:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    522: 
1.142     brouard   523:   Revision 1.141  2014/01/26 02:42:01  brouard
                    524:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    525: 
1.141     brouard   526:   Revision 1.140  2011/09/02 10:37:54  brouard
                    527:   Summary: times.h is ok with mingw32 now.
                    528: 
1.140     brouard   529:   Revision 1.139  2010/06/14 07:50:17  brouard
                    530:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    531:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    532: 
1.139     brouard   533:   Revision 1.138  2010/04/30 18:19:40  brouard
                    534:   *** empty log message ***
                    535: 
1.138     brouard   536:   Revision 1.137  2010/04/29 18:11:38  brouard
                    537:   (Module): Checking covariates for more complex models
                    538:   than V1+V2. A lot of change to be done. Unstable.
                    539: 
1.137     brouard   540:   Revision 1.136  2010/04/26 20:30:53  brouard
                    541:   (Module): merging some libgsl code. Fixing computation
                    542:   of likelione (using inter/intrapolation if mle = 0) in order to
                    543:   get same likelihood as if mle=1.
                    544:   Some cleaning of code and comments added.
                    545: 
1.136     brouard   546:   Revision 1.135  2009/10/29 15:33:14  brouard
                    547:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    548: 
1.135     brouard   549:   Revision 1.134  2009/10/29 13:18:53  brouard
                    550:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    551: 
1.134     brouard   552:   Revision 1.133  2009/07/06 10:21:25  brouard
                    553:   just nforces
                    554: 
1.133     brouard   555:   Revision 1.132  2009/07/06 08:22:05  brouard
                    556:   Many tings
                    557: 
1.132     brouard   558:   Revision 1.131  2009/06/20 16:22:47  brouard
                    559:   Some dimensions resccaled
                    560: 
1.131     brouard   561:   Revision 1.130  2009/05/26 06:44:34  brouard
                    562:   (Module): Max Covariate is now set to 20 instead of 8. A
                    563:   lot of cleaning with variables initialized to 0. Trying to make
                    564:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    565: 
1.130     brouard   566:   Revision 1.129  2007/08/31 13:49:27  lievre
                    567:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    568: 
1.129     lievre    569:   Revision 1.128  2006/06/30 13:02:05  brouard
                    570:   (Module): Clarifications on computing e.j
                    571: 
1.128     brouard   572:   Revision 1.127  2006/04/28 18:11:50  brouard
                    573:   (Module): Yes the sum of survivors was wrong since
                    574:   imach-114 because nhstepm was no more computed in the age
                    575:   loop. Now we define nhstepma in the age loop.
                    576:   (Module): In order to speed up (in case of numerous covariates) we
                    577:   compute health expectancies (without variances) in a first step
                    578:   and then all the health expectancies with variances or standard
                    579:   deviation (needs data from the Hessian matrices) which slows the
                    580:   computation.
                    581:   In the future we should be able to stop the program is only health
                    582:   expectancies and graph are needed without standard deviations.
                    583: 
1.127     brouard   584:   Revision 1.126  2006/04/28 17:23:28  brouard
                    585:   (Module): Yes the sum of survivors was wrong since
                    586:   imach-114 because nhstepm was no more computed in the age
                    587:   loop. Now we define nhstepma in the age loop.
                    588:   Version 0.98h
                    589: 
1.126     brouard   590:   Revision 1.125  2006/04/04 15:20:31  lievre
                    591:   Errors in calculation of health expectancies. Age was not initialized.
                    592:   Forecasting file added.
                    593: 
                    594:   Revision 1.124  2006/03/22 17:13:53  lievre
                    595:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    596:   The log-likelihood is printed in the log file
                    597: 
                    598:   Revision 1.123  2006/03/20 10:52:43  brouard
                    599:   * imach.c (Module): <title> changed, corresponds to .htm file
                    600:   name. <head> headers where missing.
                    601: 
                    602:   * imach.c (Module): Weights can have a decimal point as for
                    603:   English (a comma might work with a correct LC_NUMERIC environment,
                    604:   otherwise the weight is truncated).
                    605:   Modification of warning when the covariates values are not 0 or
                    606:   1.
                    607:   Version 0.98g
                    608: 
                    609:   Revision 1.122  2006/03/20 09:45:41  brouard
                    610:   (Module): Weights can have a decimal point as for
                    611:   English (a comma might work with a correct LC_NUMERIC environment,
                    612:   otherwise the weight is truncated).
                    613:   Modification of warning when the covariates values are not 0 or
                    614:   1.
                    615:   Version 0.98g
                    616: 
                    617:   Revision 1.121  2006/03/16 17:45:01  lievre
                    618:   * imach.c (Module): Comments concerning covariates added
                    619: 
                    620:   * imach.c (Module): refinements in the computation of lli if
                    621:   status=-2 in order to have more reliable computation if stepm is
                    622:   not 1 month. Version 0.98f
                    623: 
                    624:   Revision 1.120  2006/03/16 15:10:38  lievre
                    625:   (Module): refinements in the computation of lli if
                    626:   status=-2 in order to have more reliable computation if stepm is
                    627:   not 1 month. Version 0.98f
                    628: 
                    629:   Revision 1.119  2006/03/15 17:42:26  brouard
                    630:   (Module): Bug if status = -2, the loglikelihood was
                    631:   computed as likelihood omitting the logarithm. Version O.98e
                    632: 
                    633:   Revision 1.118  2006/03/14 18:20:07  brouard
                    634:   (Module): varevsij Comments added explaining the second
                    635:   table of variances if popbased=1 .
                    636:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    637:   (Module): Function pstamp added
                    638:   (Module): Version 0.98d
                    639: 
                    640:   Revision 1.117  2006/03/14 17:16:22  brouard
                    641:   (Module): varevsij Comments added explaining the second
                    642:   table of variances if popbased=1 .
                    643:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    644:   (Module): Function pstamp added
                    645:   (Module): Version 0.98d
                    646: 
                    647:   Revision 1.116  2006/03/06 10:29:27  brouard
                    648:   (Module): Variance-covariance wrong links and
                    649:   varian-covariance of ej. is needed (Saito).
                    650: 
                    651:   Revision 1.115  2006/02/27 12:17:45  brouard
                    652:   (Module): One freematrix added in mlikeli! 0.98c
                    653: 
                    654:   Revision 1.114  2006/02/26 12:57:58  brouard
                    655:   (Module): Some improvements in processing parameter
                    656:   filename with strsep.
                    657: 
                    658:   Revision 1.113  2006/02/24 14:20:24  brouard
                    659:   (Module): Memory leaks checks with valgrind and:
                    660:   datafile was not closed, some imatrix were not freed and on matrix
                    661:   allocation too.
                    662: 
                    663:   Revision 1.112  2006/01/30 09:55:26  brouard
                    664:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    665: 
                    666:   Revision 1.111  2006/01/25 20:38:18  brouard
                    667:   (Module): Lots of cleaning and bugs added (Gompertz)
                    668:   (Module): Comments can be added in data file. Missing date values
                    669:   can be a simple dot '.'.
                    670: 
                    671:   Revision 1.110  2006/01/25 00:51:50  brouard
                    672:   (Module): Lots of cleaning and bugs added (Gompertz)
                    673: 
                    674:   Revision 1.109  2006/01/24 19:37:15  brouard
                    675:   (Module): Comments (lines starting with a #) are allowed in data.
                    676: 
                    677:   Revision 1.108  2006/01/19 18:05:42  lievre
                    678:   Gnuplot problem appeared...
                    679:   To be fixed
                    680: 
                    681:   Revision 1.107  2006/01/19 16:20:37  brouard
                    682:   Test existence of gnuplot in imach path
                    683: 
                    684:   Revision 1.106  2006/01/19 13:24:36  brouard
                    685:   Some cleaning and links added in html output
                    686: 
                    687:   Revision 1.105  2006/01/05 20:23:19  lievre
                    688:   *** empty log message ***
                    689: 
                    690:   Revision 1.104  2005/09/30 16:11:43  lievre
                    691:   (Module): sump fixed, loop imx fixed, and simplifications.
                    692:   (Module): If the status is missing at the last wave but we know
                    693:   that the person is alive, then we can code his/her status as -2
                    694:   (instead of missing=-1 in earlier versions) and his/her
                    695:   contributions to the likelihood is 1 - Prob of dying from last
                    696:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    697:   the healthy state at last known wave). Version is 0.98
                    698: 
                    699:   Revision 1.103  2005/09/30 15:54:49  lievre
                    700:   (Module): sump fixed, loop imx fixed, and simplifications.
                    701: 
                    702:   Revision 1.102  2004/09/15 17:31:30  brouard
                    703:   Add the possibility to read data file including tab characters.
                    704: 
                    705:   Revision 1.101  2004/09/15 10:38:38  brouard
                    706:   Fix on curr_time
                    707: 
                    708:   Revision 1.100  2004/07/12 18:29:06  brouard
                    709:   Add version for Mac OS X. Just define UNIX in Makefile
                    710: 
                    711:   Revision 1.99  2004/06/05 08:57:40  brouard
                    712:   *** empty log message ***
                    713: 
                    714:   Revision 1.98  2004/05/16 15:05:56  brouard
                    715:   New version 0.97 . First attempt to estimate force of mortality
                    716:   directly from the data i.e. without the need of knowing the health
                    717:   state at each age, but using a Gompertz model: log u =a + b*age .
                    718:   This is the basic analysis of mortality and should be done before any
                    719:   other analysis, in order to test if the mortality estimated from the
                    720:   cross-longitudinal survey is different from the mortality estimated
                    721:   from other sources like vital statistic data.
                    722: 
                    723:   The same imach parameter file can be used but the option for mle should be -3.
                    724: 
1.133     brouard   725:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   726:   former routines in order to include the new code within the former code.
                    727: 
                    728:   The output is very simple: only an estimate of the intercept and of
                    729:   the slope with 95% confident intervals.
                    730: 
                    731:   Current limitations:
                    732:   A) Even if you enter covariates, i.e. with the
                    733:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    734:   B) There is no computation of Life Expectancy nor Life Table.
                    735: 
                    736:   Revision 1.97  2004/02/20 13:25:42  lievre
                    737:   Version 0.96d. Population forecasting command line is (temporarily)
                    738:   suppressed.
                    739: 
                    740:   Revision 1.96  2003/07/15 15:38:55  brouard
                    741:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    742:   rewritten within the same printf. Workaround: many printfs.
                    743: 
                    744:   Revision 1.95  2003/07/08 07:54:34  brouard
                    745:   * imach.c (Repository):
                    746:   (Repository): Using imachwizard code to output a more meaningful covariance
                    747:   matrix (cov(a12,c31) instead of numbers.
                    748: 
                    749:   Revision 1.94  2003/06/27 13:00:02  brouard
                    750:   Just cleaning
                    751: 
                    752:   Revision 1.93  2003/06/25 16:33:55  brouard
                    753:   (Module): On windows (cygwin) function asctime_r doesn't
                    754:   exist so I changed back to asctime which exists.
                    755:   (Module): Version 0.96b
                    756: 
                    757:   Revision 1.92  2003/06/25 16:30:45  brouard
                    758:   (Module): On windows (cygwin) function asctime_r doesn't
                    759:   exist so I changed back to asctime which exists.
                    760: 
                    761:   Revision 1.91  2003/06/25 15:30:29  brouard
                    762:   * imach.c (Repository): Duplicated warning errors corrected.
                    763:   (Repository): Elapsed time after each iteration is now output. It
                    764:   helps to forecast when convergence will be reached. Elapsed time
                    765:   is stamped in powell.  We created a new html file for the graphs
                    766:   concerning matrix of covariance. It has extension -cov.htm.
                    767: 
                    768:   Revision 1.90  2003/06/24 12:34:15  brouard
                    769:   (Module): Some bugs corrected for windows. Also, when
                    770:   mle=-1 a template is output in file "or"mypar.txt with the design
                    771:   of the covariance matrix to be input.
                    772: 
                    773:   Revision 1.89  2003/06/24 12:30:52  brouard
                    774:   (Module): Some bugs corrected for windows. Also, when
                    775:   mle=-1 a template is output in file "or"mypar.txt with the design
                    776:   of the covariance matrix to be input.
                    777: 
                    778:   Revision 1.88  2003/06/23 17:54:56  brouard
                    779:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    780: 
                    781:   Revision 1.87  2003/06/18 12:26:01  brouard
                    782:   Version 0.96
                    783: 
                    784:   Revision 1.86  2003/06/17 20:04:08  brouard
                    785:   (Module): Change position of html and gnuplot routines and added
                    786:   routine fileappend.
                    787: 
                    788:   Revision 1.85  2003/06/17 13:12:43  brouard
                    789:   * imach.c (Repository): Check when date of death was earlier that
                    790:   current date of interview. It may happen when the death was just
                    791:   prior to the death. In this case, dh was negative and likelihood
                    792:   was wrong (infinity). We still send an "Error" but patch by
                    793:   assuming that the date of death was just one stepm after the
                    794:   interview.
                    795:   (Repository): Because some people have very long ID (first column)
                    796:   we changed int to long in num[] and we added a new lvector for
                    797:   memory allocation. But we also truncated to 8 characters (left
                    798:   truncation)
                    799:   (Repository): No more line truncation errors.
                    800: 
                    801:   Revision 1.84  2003/06/13 21:44:43  brouard
                    802:   * imach.c (Repository): Replace "freqsummary" at a correct
                    803:   place. It differs from routine "prevalence" which may be called
                    804:   many times. Probs is memory consuming and must be used with
                    805:   parcimony.
                    806:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    807: 
                    808:   Revision 1.83  2003/06/10 13:39:11  lievre
                    809:   *** empty log message ***
                    810: 
                    811:   Revision 1.82  2003/06/05 15:57:20  brouard
                    812:   Add log in  imach.c and  fullversion number is now printed.
                    813: 
                    814: */
                    815: /*
                    816:    Interpolated Markov Chain
                    817: 
                    818:   Short summary of the programme:
                    819:   
1.227     brouard   820:   This program computes Healthy Life Expectancies or State-specific
                    821:   (if states aren't health statuses) Expectancies from
                    822:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    823: 
                    824:   -1- a first survey ("cross") where individuals from different ages
                    825:   are interviewed on their health status or degree of disability (in
                    826:   the case of a health survey which is our main interest)
                    827: 
                    828:   -2- at least a second wave of interviews ("longitudinal") which
                    829:   measure each change (if any) in individual health status.  Health
                    830:   expectancies are computed from the time spent in each health state
                    831:   according to a model. More health states you consider, more time is
                    832:   necessary to reach the Maximum Likelihood of the parameters involved
                    833:   in the model.  The simplest model is the multinomial logistic model
                    834:   where pij is the probability to be observed in state j at the second
                    835:   wave conditional to be observed in state i at the first
                    836:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    837:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    838:   have a more complex model than "constant and age", you should modify
                    839:   the program where the markup *Covariates have to be included here
                    840:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   841:   convergence.
                    842: 
                    843:   The advantage of this computer programme, compared to a simple
                    844:   multinomial logistic model, is clear when the delay between waves is not
                    845:   identical for each individual. Also, if a individual missed an
                    846:   intermediate interview, the information is lost, but taken into
                    847:   account using an interpolation or extrapolation.  
                    848: 
                    849:   hPijx is the probability to be observed in state i at age x+h
                    850:   conditional to the observed state i at age x. The delay 'h' can be
                    851:   split into an exact number (nh*stepm) of unobserved intermediate
                    852:   states. This elementary transition (by month, quarter,
                    853:   semester or year) is modelled as a multinomial logistic.  The hPx
                    854:   matrix is simply the matrix product of nh*stepm elementary matrices
                    855:   and the contribution of each individual to the likelihood is simply
                    856:   hPijx.
                    857: 
                    858:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   859:   of the life expectancies. It also computes the period (stable) prevalence.
                    860: 
                    861: Back prevalence and projections:
1.227     brouard   862: 
                    863:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    864:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    865:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    866:    mobilavproj)
                    867: 
                    868:     Computes the back prevalence limit for any combination of
                    869:     covariate values k at any age between ageminpar and agemaxpar and
                    870:     returns it in **bprlim. In the loops,
                    871: 
                    872:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    873:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    874: 
                    875:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   876:    Computes for any combination of covariates k and any age between bage and fage 
                    877:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    878:                        oldm=oldms;savm=savms;
1.227     brouard   879: 
1.267     brouard   880:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   881:      Computes the transition matrix starting at age 'age' over
                    882:      'nhstepm*hstepm*stepm' months (i.e. until
                    883:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   884:      nhstepm*hstepm matrices. 
                    885: 
                    886:      Returns p3mat[i][j][h] after calling
                    887:      p3mat[i][j][h]=matprod2(newm,
                    888:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    889:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    890:      oldm);
1.226     brouard   891: 
                    892: Important routines
                    893: 
                    894: - func (or funcone), computes logit (pij) distinguishing
                    895:   o fixed variables (single or product dummies or quantitative);
                    896:   o varying variables by:
                    897:    (1) wave (single, product dummies, quantitative), 
                    898:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    899:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    900:        % varying dummy (not done) or quantitative (not done);
                    901: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    902:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    903: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    904:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    905:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   906: 
1.226     brouard   907: 
                    908:   
1.133     brouard   909:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    910:            Institut national d'études démographiques, Paris.
1.126     brouard   911:   This software have been partly granted by Euro-REVES, a concerted action
                    912:   from the European Union.
                    913:   It is copyrighted identically to a GNU software product, ie programme and
                    914:   software can be distributed freely for non commercial use. Latest version
                    915:   can be accessed at http://euroreves.ined.fr/imach .
                    916: 
                    917:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    918:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    919:   
                    920:   **********************************************************************/
                    921: /*
                    922:   main
                    923:   read parameterfile
                    924:   read datafile
                    925:   concatwav
                    926:   freqsummary
                    927:   if (mle >= 1)
                    928:     mlikeli
                    929:   print results files
                    930:   if mle==1 
                    931:      computes hessian
                    932:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    933:       begin-prev-date,...
                    934:   open gnuplot file
                    935:   open html file
1.145     brouard   936:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    937:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    938:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    939:     freexexit2 possible for memory heap.
                    940: 
                    941:   h Pij x                         | pij_nom  ficrestpij
                    942:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    943:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    944:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    945: 
                    946:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    947:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    948:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    949:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    950:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    951: 
1.126     brouard   952:   forecasting if prevfcast==1 prevforecast call prevalence()
                    953:   health expectancies
                    954:   Variance-covariance of DFLE
                    955:   prevalence()
                    956:    movingaverage()
                    957:   varevsij() 
                    958:   if popbased==1 varevsij(,popbased)
                    959:   total life expectancies
                    960:   Variance of period (stable) prevalence
                    961:  end
                    962: */
                    963: 
1.187     brouard   964: /* #define DEBUG */
                    965: /* #define DEBUGBRENT */
1.203     brouard   966: /* #define DEBUGLINMIN */
                    967: /* #define DEBUGHESS */
                    968: #define DEBUGHESSIJ
1.224     brouard   969: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   970: #define POWELL /* Instead of NLOPT */
1.224     brouard   971: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   972: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    973: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   974: 
                    975: #include <math.h>
                    976: #include <stdio.h>
                    977: #include <stdlib.h>
                    978: #include <string.h>
1.226     brouard   979: #include <ctype.h>
1.159     brouard   980: 
                    981: #ifdef _WIN32
                    982: #include <io.h>
1.172     brouard   983: #include <windows.h>
                    984: #include <tchar.h>
1.159     brouard   985: #else
1.126     brouard   986: #include <unistd.h>
1.159     brouard   987: #endif
1.126     brouard   988: 
                    989: #include <limits.h>
                    990: #include <sys/types.h>
1.171     brouard   991: 
                    992: #if defined(__GNUC__)
                    993: #include <sys/utsname.h> /* Doesn't work on Windows */
                    994: #endif
                    995: 
1.126     brouard   996: #include <sys/stat.h>
                    997: #include <errno.h>
1.159     brouard   998: /* extern int errno; */
1.126     brouard   999: 
1.157     brouard  1000: /* #ifdef LINUX */
                   1001: /* #include <time.h> */
                   1002: /* #include "timeval.h" */
                   1003: /* #else */
                   1004: /* #include <sys/time.h> */
                   1005: /* #endif */
                   1006: 
1.126     brouard  1007: #include <time.h>
                   1008: 
1.136     brouard  1009: #ifdef GSL
                   1010: #include <gsl/gsl_errno.h>
                   1011: #include <gsl/gsl_multimin.h>
                   1012: #endif
                   1013: 
1.167     brouard  1014: 
1.162     brouard  1015: #ifdef NLOPT
                   1016: #include <nlopt.h>
                   1017: typedef struct {
                   1018:   double (* function)(double [] );
                   1019: } myfunc_data ;
                   1020: #endif
                   1021: 
1.126     brouard  1022: /* #include <libintl.h> */
                   1023: /* #define _(String) gettext (String) */
                   1024: 
1.251     brouard  1025: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1026: 
                   1027: #define GNUPLOTPROGRAM "gnuplot"
                   1028: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1029: #define FILENAMELENGTH 132
                   1030: 
                   1031: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1032: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1033: 
1.144     brouard  1034: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1035: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1036: 
                   1037: #define NINTERVMAX 8
1.144     brouard  1038: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1039: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                   1040: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1041: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1042: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1043: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1044: #define MAXN 20000
1.144     brouard  1045: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1046: /* #define AGESUP 130 */
                   1047: #define AGESUP 150
1.268     brouard  1048: #define AGEINF 0
1.218     brouard  1049: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1050: #define AGEBASE 40
1.194     brouard  1051: #define AGEOVERFLOW 1.e20
1.164     brouard  1052: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1053: #ifdef _WIN32
                   1054: #define DIRSEPARATOR '\\'
                   1055: #define CHARSEPARATOR "\\"
                   1056: #define ODIRSEPARATOR '/'
                   1057: #else
1.126     brouard  1058: #define DIRSEPARATOR '/'
                   1059: #define CHARSEPARATOR "/"
                   1060: #define ODIRSEPARATOR '\\'
                   1061: #endif
                   1062: 
1.286   ! brouard  1063: /* $Id: imach.c,v 1.285 2018/04/21 21:02:16 brouard Exp $ */
1.126     brouard  1064: /* $State: Exp $ */
1.196     brouard  1065: #include "version.h"
                   1066: char version[]=__IMACH_VERSION__;
1.283     brouard  1067: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.286   ! brouard  1068: char fullversion[]="$Revision: 1.285 $ $Date: 2018/04/21 21:02:16 $"; 
1.126     brouard  1069: char strstart[80];
                   1070: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1071: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1072: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1073: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1074: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1075: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1076: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1077: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1078: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1079: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1080: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1081: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1082: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1083: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1084: int nsd=0; /**< Total number of single dummy variables (output) */
                   1085: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1086: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1087: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1088: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1089: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1090: int cptcov=0; /* Working variable */
1.218     brouard  1091: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1092: int npar=NPARMAX;
                   1093: int nlstate=2; /* Number of live states */
                   1094: int ndeath=1; /* Number of dead states */
1.130     brouard  1095: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1096: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1097: int popbased=0;
                   1098: 
                   1099: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1100: int maxwav=0; /* Maxim number of waves */
                   1101: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1102: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1103: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1104:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1105: int mle=1, weightopt=0;
1.126     brouard  1106: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1107: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1108: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1109:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1110: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1111: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1112: 
1.130     brouard  1113: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1114: double **matprod2(); /* test */
1.126     brouard  1115: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1116: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1117: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1118: 
1.136     brouard  1119: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1120: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1121: FILE *ficlog, *ficrespow;
1.130     brouard  1122: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1123: double fretone; /* Only one call to likelihood */
1.130     brouard  1124: long ipmx=0; /* Number of contributions */
1.126     brouard  1125: double sw; /* Sum of weights */
                   1126: char filerespow[FILENAMELENGTH];
                   1127: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1128: FILE *ficresilk;
                   1129: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1130: FILE *ficresprobmorprev;
                   1131: FILE *fichtm, *fichtmcov; /* Html File */
                   1132: FILE *ficreseij;
                   1133: char filerese[FILENAMELENGTH];
                   1134: FILE *ficresstdeij;
                   1135: char fileresstde[FILENAMELENGTH];
                   1136: FILE *ficrescveij;
                   1137: char filerescve[FILENAMELENGTH];
                   1138: FILE  *ficresvij;
                   1139: char fileresv[FILENAMELENGTH];
1.269     brouard  1140: 
1.126     brouard  1141: char title[MAXLINE];
1.234     brouard  1142: char model[MAXLINE]; /**< The model line */
1.217     brouard  1143: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1144: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1145: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1146: char command[FILENAMELENGTH];
                   1147: int  outcmd=0;
                   1148: 
1.217     brouard  1149: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1150: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1151: char filelog[FILENAMELENGTH]; /* Log file */
                   1152: char filerest[FILENAMELENGTH];
                   1153: char fileregp[FILENAMELENGTH];
                   1154: char popfile[FILENAMELENGTH];
                   1155: 
                   1156: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1157: 
1.157     brouard  1158: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1159: /* struct timezone tzp; */
                   1160: /* extern int gettimeofday(); */
                   1161: struct tm tml, *gmtime(), *localtime();
                   1162: 
                   1163: extern time_t time();
                   1164: 
                   1165: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1166: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1167: struct tm tm;
                   1168: 
1.126     brouard  1169: char strcurr[80], strfor[80];
                   1170: 
                   1171: char *endptr;
                   1172: long lval;
                   1173: double dval;
                   1174: 
                   1175: #define NR_END 1
                   1176: #define FREE_ARG char*
                   1177: #define FTOL 1.0e-10
                   1178: 
                   1179: #define NRANSI 
1.240     brouard  1180: #define ITMAX 200
                   1181: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1182: 
                   1183: #define TOL 2.0e-4 
                   1184: 
                   1185: #define CGOLD 0.3819660 
                   1186: #define ZEPS 1.0e-10 
                   1187: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1188: 
                   1189: #define GOLD 1.618034 
                   1190: #define GLIMIT 100.0 
                   1191: #define TINY 1.0e-20 
                   1192: 
                   1193: static double maxarg1,maxarg2;
                   1194: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1195: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1196:   
                   1197: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1198: #define rint(a) floor(a+0.5)
1.166     brouard  1199: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1200: #define mytinydouble 1.0e-16
1.166     brouard  1201: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1202: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1203: /* static double dsqrarg; */
                   1204: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1205: static double sqrarg;
                   1206: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1207: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1208: int agegomp= AGEGOMP;
                   1209: 
                   1210: int imx; 
                   1211: int stepm=1;
                   1212: /* Stepm, step in month: minimum step interpolation*/
                   1213: 
                   1214: int estepm;
                   1215: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1216: 
                   1217: int m,nb;
                   1218: long *num;
1.197     brouard  1219: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1220: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1221:                   covariate for which somebody answered excluding 
                   1222:                   undefined. Usually 2: 0 and 1. */
                   1223: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1224:                             covariate for which somebody answered including 
                   1225:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1226: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1227: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1228: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1229: double *ageexmed,*agecens;
                   1230: double dateintmean=0;
                   1231: 
                   1232: double *weight;
                   1233: int **s; /* Status */
1.141     brouard  1234: double *agedc;
1.145     brouard  1235: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1236:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1237:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1238: double **coqvar; /* Fixed quantitative covariate nqv */
                   1239: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1240: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1241: double  idx; 
                   1242: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1243: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1244: /*k          1  2   3   4     5    6    7     8    9 */
                   1245: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1246: /* Tndvar[k]    1   2   3               4          5 */
                   1247: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1248: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1249: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1250: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1251: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1252: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1253: /* Tprod[i]=k           4               7            */
                   1254: /* Tage[i]=k                  5               8      */
                   1255: /* */
                   1256: /* Type                    */
                   1257: /* V         1  2  3  4  5 */
                   1258: /*           F  F  V  V  V */
                   1259: /*           D  Q  D  D  Q */
                   1260: /*                         */
                   1261: int *TvarsD;
                   1262: int *TvarsDind;
                   1263: int *TvarsQ;
                   1264: int *TvarsQind;
                   1265: 
1.235     brouard  1266: #define MAXRESULTLINES 10
                   1267: int nresult=0;
1.258     brouard  1268: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1269: int TKresult[MAXRESULTLINES];
1.237     brouard  1270: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1271: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1272: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1273: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1274: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1275: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1276: 
1.234     brouard  1277: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1278: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1279: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1280: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1281: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1282: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1283: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1284: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1285: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1286: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1287: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1288: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1289: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1290: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1291: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1292: 
1.230     brouard  1293: int *Tvarsel; /**< Selected covariates for output */
                   1294: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1295: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1296: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1297: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1298: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1299: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1300: int *Tage;
1.227     brouard  1301: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1302: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1303: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1304: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1305: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1306: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1307: int **Tvard;
                   1308: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1309: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1310: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1311:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1312:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1313: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1314: double *lsurv, *lpop, *tpop;
                   1315: 
1.231     brouard  1316: #define FD 1; /* Fixed dummy covariate */
                   1317: #define FQ 2; /* Fixed quantitative covariate */
                   1318: #define FP 3; /* Fixed product covariate */
                   1319: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1320: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1321: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1322: #define VD 10; /* Varying dummy covariate */
                   1323: #define VQ 11; /* Varying quantitative covariate */
                   1324: #define VP 12; /* Varying product covariate */
                   1325: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1326: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1327: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1328: #define APFD 16; /* Age product * fixed dummy covariate */
                   1329: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1330: #define APVD 18; /* Age product * varying dummy covariate */
                   1331: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1332: 
                   1333: #define FTYPE 1; /* Fixed covariate */
                   1334: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1335: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1336: 
                   1337: struct kmodel{
                   1338:        int maintype; /* main type */
                   1339:        int subtype; /* subtype */
                   1340: };
                   1341: struct kmodel modell[NCOVMAX];
                   1342: 
1.143     brouard  1343: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1344: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1345: 
                   1346: /**************** split *************************/
                   1347: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1348: {
                   1349:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1350:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1351:   */ 
                   1352:   char *ss;                            /* pointer */
1.186     brouard  1353:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1354: 
                   1355:   l1 = strlen(path );                  /* length of path */
                   1356:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1357:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1358:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1359:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1360:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1361:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1362:     /* get current working directory */
                   1363:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1364: #ifdef WIN32
                   1365:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1366: #else
                   1367:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1368: #endif
1.126     brouard  1369:       return( GLOCK_ERROR_GETCWD );
                   1370:     }
                   1371:     /* got dirc from getcwd*/
                   1372:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1373:   } else {                             /* strip directory from path */
1.126     brouard  1374:     ss++;                              /* after this, the filename */
                   1375:     l2 = strlen( ss );                 /* length of filename */
                   1376:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1377:     strcpy( name, ss );                /* save file name */
                   1378:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1379:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1380:     printf(" DIRC2 = %s \n",dirc);
                   1381:   }
                   1382:   /* We add a separator at the end of dirc if not exists */
                   1383:   l1 = strlen( dirc );                 /* length of directory */
                   1384:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1385:     dirc[l1] =  DIRSEPARATOR;
                   1386:     dirc[l1+1] = 0; 
                   1387:     printf(" DIRC3 = %s \n",dirc);
                   1388:   }
                   1389:   ss = strrchr( name, '.' );           /* find last / */
                   1390:   if (ss >0){
                   1391:     ss++;
                   1392:     strcpy(ext,ss);                    /* save extension */
                   1393:     l1= strlen( name);
                   1394:     l2= strlen(ss)+1;
                   1395:     strncpy( finame, name, l1-l2);
                   1396:     finame[l1-l2]= 0;
                   1397:   }
                   1398: 
                   1399:   return( 0 );                         /* we're done */
                   1400: }
                   1401: 
                   1402: 
                   1403: /******************************************/
                   1404: 
                   1405: void replace_back_to_slash(char *s, char*t)
                   1406: {
                   1407:   int i;
                   1408:   int lg=0;
                   1409:   i=0;
                   1410:   lg=strlen(t);
                   1411:   for(i=0; i<= lg; i++) {
                   1412:     (s[i] = t[i]);
                   1413:     if (t[i]== '\\') s[i]='/';
                   1414:   }
                   1415: }
                   1416: 
1.132     brouard  1417: char *trimbb(char *out, char *in)
1.137     brouard  1418: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1419:   char *s;
                   1420:   s=out;
                   1421:   while (*in != '\0'){
1.137     brouard  1422:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1423:       in++;
                   1424:     }
                   1425:     *out++ = *in++;
                   1426:   }
                   1427:   *out='\0';
                   1428:   return s;
                   1429: }
                   1430: 
1.187     brouard  1431: /* char *substrchaine(char *out, char *in, char *chain) */
                   1432: /* { */
                   1433: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1434: /*   char *s, *t; */
                   1435: /*   t=in;s=out; */
                   1436: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1437: /*     *out++ = *in++; */
                   1438: /*   } */
                   1439: 
                   1440: /*   /\* *in matches *chain *\/ */
                   1441: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1442: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1443: /*   } */
                   1444: /*   in--; chain--; */
                   1445: /*   while ( (*in != '\0')){ */
                   1446: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1447: /*     *out++ = *in++; */
                   1448: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1449: /*   } */
                   1450: /*   *out='\0'; */
                   1451: /*   out=s; */
                   1452: /*   return out; */
                   1453: /* } */
                   1454: char *substrchaine(char *out, char *in, char *chain)
                   1455: {
                   1456:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1457:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1458: 
                   1459:   char *strloc;
                   1460: 
                   1461:   strcpy (out, in); 
                   1462:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1463:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1464:   if(strloc != NULL){ 
                   1465:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1466:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1467:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1468:   }
                   1469:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1470:   return out;
                   1471: }
                   1472: 
                   1473: 
1.145     brouard  1474: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1475: {
1.187     brouard  1476:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1477:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1478:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1479:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1480:   */
1.160     brouard  1481:   char *s, *t;
1.145     brouard  1482:   t=in;s=in;
                   1483:   while ((*in != occ) && (*in != '\0')){
                   1484:     *alocc++ = *in++;
                   1485:   }
                   1486:   if( *in == occ){
                   1487:     *(alocc)='\0';
                   1488:     s=++in;
                   1489:   }
                   1490:  
                   1491:   if (s == t) {/* occ not found */
                   1492:     *(alocc-(in-s))='\0';
                   1493:     in=s;
                   1494:   }
                   1495:   while ( *in != '\0'){
                   1496:     *blocc++ = *in++;
                   1497:   }
                   1498: 
                   1499:   *blocc='\0';
                   1500:   return t;
                   1501: }
1.137     brouard  1502: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1503: {
1.187     brouard  1504:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1505:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1506:      gives blocc="abcdef2ghi" and alocc="j".
                   1507:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1508:   */
                   1509:   char *s, *t;
                   1510:   t=in;s=in;
                   1511:   while (*in != '\0'){
                   1512:     while( *in == occ){
                   1513:       *blocc++ = *in++;
                   1514:       s=in;
                   1515:     }
                   1516:     *blocc++ = *in++;
                   1517:   }
                   1518:   if (s == t) /* occ not found */
                   1519:     *(blocc-(in-s))='\0';
                   1520:   else
                   1521:     *(blocc-(in-s)-1)='\0';
                   1522:   in=s;
                   1523:   while ( *in != '\0'){
                   1524:     *alocc++ = *in++;
                   1525:   }
                   1526: 
                   1527:   *alocc='\0';
                   1528:   return s;
                   1529: }
                   1530: 
1.126     brouard  1531: int nbocc(char *s, char occ)
                   1532: {
                   1533:   int i,j=0;
                   1534:   int lg=20;
                   1535:   i=0;
                   1536:   lg=strlen(s);
                   1537:   for(i=0; i<= lg; i++) {
1.234     brouard  1538:     if  (s[i] == occ ) j++;
1.126     brouard  1539:   }
                   1540:   return j;
                   1541: }
                   1542: 
1.137     brouard  1543: /* void cutv(char *u,char *v, char*t, char occ) */
                   1544: /* { */
                   1545: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1546: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1547: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1548: /*   int i,lg,j,p=0; */
                   1549: /*   i=0; */
                   1550: /*   lg=strlen(t); */
                   1551: /*   for(j=0; j<=lg-1; j++) { */
                   1552: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1553: /*   } */
1.126     brouard  1554: 
1.137     brouard  1555: /*   for(j=0; j<p; j++) { */
                   1556: /*     (u[j] = t[j]); */
                   1557: /*   } */
                   1558: /*      u[p]='\0'; */
1.126     brouard  1559: 
1.137     brouard  1560: /*    for(j=0; j<= lg; j++) { */
                   1561: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1562: /*   } */
                   1563: /* } */
1.126     brouard  1564: 
1.160     brouard  1565: #ifdef _WIN32
                   1566: char * strsep(char **pp, const char *delim)
                   1567: {
                   1568:   char *p, *q;
                   1569:          
                   1570:   if ((p = *pp) == NULL)
                   1571:     return 0;
                   1572:   if ((q = strpbrk (p, delim)) != NULL)
                   1573:   {
                   1574:     *pp = q + 1;
                   1575:     *q = '\0';
                   1576:   }
                   1577:   else
                   1578:     *pp = 0;
                   1579:   return p;
                   1580: }
                   1581: #endif
                   1582: 
1.126     brouard  1583: /********************** nrerror ********************/
                   1584: 
                   1585: void nrerror(char error_text[])
                   1586: {
                   1587:   fprintf(stderr,"ERREUR ...\n");
                   1588:   fprintf(stderr,"%s\n",error_text);
                   1589:   exit(EXIT_FAILURE);
                   1590: }
                   1591: /*********************** vector *******************/
                   1592: double *vector(int nl, int nh)
                   1593: {
                   1594:   double *v;
                   1595:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1596:   if (!v) nrerror("allocation failure in vector");
                   1597:   return v-nl+NR_END;
                   1598: }
                   1599: 
                   1600: /************************ free vector ******************/
                   1601: void free_vector(double*v, int nl, int nh)
                   1602: {
                   1603:   free((FREE_ARG)(v+nl-NR_END));
                   1604: }
                   1605: 
                   1606: /************************ivector *******************************/
                   1607: int *ivector(long nl,long nh)
                   1608: {
                   1609:   int *v;
                   1610:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1611:   if (!v) nrerror("allocation failure in ivector");
                   1612:   return v-nl+NR_END;
                   1613: }
                   1614: 
                   1615: /******************free ivector **************************/
                   1616: void free_ivector(int *v, long nl, long nh)
                   1617: {
                   1618:   free((FREE_ARG)(v+nl-NR_END));
                   1619: }
                   1620: 
                   1621: /************************lvector *******************************/
                   1622: long *lvector(long nl,long nh)
                   1623: {
                   1624:   long *v;
                   1625:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1626:   if (!v) nrerror("allocation failure in ivector");
                   1627:   return v-nl+NR_END;
                   1628: }
                   1629: 
                   1630: /******************free lvector **************************/
                   1631: void free_lvector(long *v, long nl, long nh)
                   1632: {
                   1633:   free((FREE_ARG)(v+nl-NR_END));
                   1634: }
                   1635: 
                   1636: /******************* imatrix *******************************/
                   1637: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1638:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1639: { 
                   1640:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1641:   int **m; 
                   1642:   
                   1643:   /* allocate pointers to rows */ 
                   1644:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1645:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1646:   m += NR_END; 
                   1647:   m -= nrl; 
                   1648:   
                   1649:   
                   1650:   /* allocate rows and set pointers to them */ 
                   1651:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1652:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1653:   m[nrl] += NR_END; 
                   1654:   m[nrl] -= ncl; 
                   1655:   
                   1656:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1657:   
                   1658:   /* return pointer to array of pointers to rows */ 
                   1659:   return m; 
                   1660: } 
                   1661: 
                   1662: /****************** free_imatrix *************************/
                   1663: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1664:       int **m;
                   1665:       long nch,ncl,nrh,nrl; 
                   1666:      /* free an int matrix allocated by imatrix() */ 
                   1667: { 
                   1668:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1669:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1670: } 
                   1671: 
                   1672: /******************* matrix *******************************/
                   1673: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1674: {
                   1675:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1676:   double **m;
                   1677: 
                   1678:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1679:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1680:   m += NR_END;
                   1681:   m -= nrl;
                   1682: 
                   1683:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1684:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1685:   m[nrl] += NR_END;
                   1686:   m[nrl] -= ncl;
                   1687: 
                   1688:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1689:   return m;
1.145     brouard  1690:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1691: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1692: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1693:    */
                   1694: }
                   1695: 
                   1696: /*************************free matrix ************************/
                   1697: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1698: {
                   1699:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1700:   free((FREE_ARG)(m+nrl-NR_END));
                   1701: }
                   1702: 
                   1703: /******************* ma3x *******************************/
                   1704: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1705: {
                   1706:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1707:   double ***m;
                   1708: 
                   1709:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1710:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1711:   m += NR_END;
                   1712:   m -= nrl;
                   1713: 
                   1714:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1715:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1716:   m[nrl] += NR_END;
                   1717:   m[nrl] -= ncl;
                   1718: 
                   1719:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1720: 
                   1721:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1722:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1723:   m[nrl][ncl] += NR_END;
                   1724:   m[nrl][ncl] -= nll;
                   1725:   for (j=ncl+1; j<=nch; j++) 
                   1726:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1727:   
                   1728:   for (i=nrl+1; i<=nrh; i++) {
                   1729:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1730:     for (j=ncl+1; j<=nch; j++) 
                   1731:       m[i][j]=m[i][j-1]+nlay;
                   1732:   }
                   1733:   return m; 
                   1734:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1735:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1736:   */
                   1737: }
                   1738: 
                   1739: /*************************free ma3x ************************/
                   1740: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1741: {
                   1742:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1743:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1744:   free((FREE_ARG)(m+nrl-NR_END));
                   1745: }
                   1746: 
                   1747: /*************** function subdirf ***********/
                   1748: char *subdirf(char fileres[])
                   1749: {
                   1750:   /* Caution optionfilefiname is hidden */
                   1751:   strcpy(tmpout,optionfilefiname);
                   1752:   strcat(tmpout,"/"); /* Add to the right */
                   1753:   strcat(tmpout,fileres);
                   1754:   return tmpout;
                   1755: }
                   1756: 
                   1757: /*************** function subdirf2 ***********/
                   1758: char *subdirf2(char fileres[], char *preop)
                   1759: {
                   1760:   
                   1761:   /* Caution optionfilefiname is hidden */
                   1762:   strcpy(tmpout,optionfilefiname);
                   1763:   strcat(tmpout,"/");
                   1764:   strcat(tmpout,preop);
                   1765:   strcat(tmpout,fileres);
                   1766:   return tmpout;
                   1767: }
                   1768: 
                   1769: /*************** function subdirf3 ***********/
                   1770: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1771: {
                   1772:   
                   1773:   /* Caution optionfilefiname is hidden */
                   1774:   strcpy(tmpout,optionfilefiname);
                   1775:   strcat(tmpout,"/");
                   1776:   strcat(tmpout,preop);
                   1777:   strcat(tmpout,preop2);
                   1778:   strcat(tmpout,fileres);
                   1779:   return tmpout;
                   1780: }
1.213     brouard  1781:  
                   1782: /*************** function subdirfext ***********/
                   1783: char *subdirfext(char fileres[], char *preop, char *postop)
                   1784: {
                   1785:   
                   1786:   strcpy(tmpout,preop);
                   1787:   strcat(tmpout,fileres);
                   1788:   strcat(tmpout,postop);
                   1789:   return tmpout;
                   1790: }
1.126     brouard  1791: 
1.213     brouard  1792: /*************** function subdirfext3 ***********/
                   1793: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1794: {
                   1795:   
                   1796:   /* Caution optionfilefiname is hidden */
                   1797:   strcpy(tmpout,optionfilefiname);
                   1798:   strcat(tmpout,"/");
                   1799:   strcat(tmpout,preop);
                   1800:   strcat(tmpout,fileres);
                   1801:   strcat(tmpout,postop);
                   1802:   return tmpout;
                   1803: }
                   1804:  
1.162     brouard  1805: char *asc_diff_time(long time_sec, char ascdiff[])
                   1806: {
                   1807:   long sec_left, days, hours, minutes;
                   1808:   days = (time_sec) / (60*60*24);
                   1809:   sec_left = (time_sec) % (60*60*24);
                   1810:   hours = (sec_left) / (60*60) ;
                   1811:   sec_left = (sec_left) %(60*60);
                   1812:   minutes = (sec_left) /60;
                   1813:   sec_left = (sec_left) % (60);
                   1814:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1815:   return ascdiff;
                   1816: }
                   1817: 
1.126     brouard  1818: /***************** f1dim *************************/
                   1819: extern int ncom; 
                   1820: extern double *pcom,*xicom;
                   1821: extern double (*nrfunc)(double []); 
                   1822:  
                   1823: double f1dim(double x) 
                   1824: { 
                   1825:   int j; 
                   1826:   double f;
                   1827:   double *xt; 
                   1828:  
                   1829:   xt=vector(1,ncom); 
                   1830:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1831:   f=(*nrfunc)(xt); 
                   1832:   free_vector(xt,1,ncom); 
                   1833:   return f; 
                   1834: } 
                   1835: 
                   1836: /*****************brent *************************/
                   1837: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1838: {
                   1839:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1840:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1841:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1842:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1843:    * returned function value. 
                   1844:   */
1.126     brouard  1845:   int iter; 
                   1846:   double a,b,d,etemp;
1.159     brouard  1847:   double fu=0,fv,fw,fx;
1.164     brouard  1848:   double ftemp=0.;
1.126     brouard  1849:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1850:   double e=0.0; 
                   1851:  
                   1852:   a=(ax < cx ? ax : cx); 
                   1853:   b=(ax > cx ? ax : cx); 
                   1854:   x=w=v=bx; 
                   1855:   fw=fv=fx=(*f)(x); 
                   1856:   for (iter=1;iter<=ITMAX;iter++) { 
                   1857:     xm=0.5*(a+b); 
                   1858:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1859:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1860:     printf(".");fflush(stdout);
                   1861:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1862: #ifdef DEBUGBRENT
1.126     brouard  1863:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1864:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1865:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1866: #endif
                   1867:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1868:       *xmin=x; 
                   1869:       return fx; 
                   1870:     } 
                   1871:     ftemp=fu;
                   1872:     if (fabs(e) > tol1) { 
                   1873:       r=(x-w)*(fx-fv); 
                   1874:       q=(x-v)*(fx-fw); 
                   1875:       p=(x-v)*q-(x-w)*r; 
                   1876:       q=2.0*(q-r); 
                   1877:       if (q > 0.0) p = -p; 
                   1878:       q=fabs(q); 
                   1879:       etemp=e; 
                   1880:       e=d; 
                   1881:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1882:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1883:       else { 
1.224     brouard  1884:                                d=p/q; 
                   1885:                                u=x+d; 
                   1886:                                if (u-a < tol2 || b-u < tol2) 
                   1887:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1888:       } 
                   1889:     } else { 
                   1890:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1891:     } 
                   1892:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1893:     fu=(*f)(u); 
                   1894:     if (fu <= fx) { 
                   1895:       if (u >= x) a=x; else b=x; 
                   1896:       SHFT(v,w,x,u) 
1.183     brouard  1897:       SHFT(fv,fw,fx,fu) 
                   1898:     } else { 
                   1899:       if (u < x) a=u; else b=u; 
                   1900:       if (fu <= fw || w == x) { 
1.224     brouard  1901:                                v=w; 
                   1902:                                w=u; 
                   1903:                                fv=fw; 
                   1904:                                fw=fu; 
1.183     brouard  1905:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1906:                                v=u; 
                   1907:                                fv=fu; 
1.183     brouard  1908:       } 
                   1909:     } 
1.126     brouard  1910:   } 
                   1911:   nrerror("Too many iterations in brent"); 
                   1912:   *xmin=x; 
                   1913:   return fx; 
                   1914: } 
                   1915: 
                   1916: /****************** mnbrak ***********************/
                   1917: 
                   1918: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1919:            double (*func)(double)) 
1.183     brouard  1920: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1921: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1922: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1923: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1924:    */
1.126     brouard  1925:   double ulim,u,r,q, dum;
                   1926:   double fu; 
1.187     brouard  1927: 
                   1928:   double scale=10.;
                   1929:   int iterscale=0;
                   1930: 
                   1931:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1932:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1933: 
                   1934: 
                   1935:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1936:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1937:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1938:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1939:   /* } */
                   1940: 
1.126     brouard  1941:   if (*fb > *fa) { 
                   1942:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1943:     SHFT(dum,*fb,*fa,dum) 
                   1944:   } 
1.126     brouard  1945:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1946:   *fc=(*func)(*cx); 
1.183     brouard  1947: #ifdef DEBUG
1.224     brouard  1948:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1949:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1950: #endif
1.224     brouard  1951:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1952:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1953:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1954:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1955:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1956:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1957:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1958:       fu=(*func)(u); 
1.163     brouard  1959: #ifdef DEBUG
                   1960:       /* f(x)=A(x-u)**2+f(u) */
                   1961:       double A, fparabu; 
                   1962:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1963:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1964:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1965:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1966:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1967:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1968:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1969:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1970: #endif 
1.184     brouard  1971: #ifdef MNBRAKORIGINAL
1.183     brouard  1972: #else
1.191     brouard  1973: /*       if (fu > *fc) { */
                   1974: /* #ifdef DEBUG */
                   1975: /*       printf("mnbrak4  fu > fc \n"); */
                   1976: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1977: /* #endif */
                   1978: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1979: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1980: /*     dum=u; /\* Shifting c and u *\/ */
                   1981: /*     u = *cx; */
                   1982: /*     *cx = dum; */
                   1983: /*     dum = fu; */
                   1984: /*     fu = *fc; */
                   1985: /*     *fc =dum; */
                   1986: /*       } else { /\* end *\/ */
                   1987: /* #ifdef DEBUG */
                   1988: /*       printf("mnbrak3  fu < fc \n"); */
                   1989: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1990: /* #endif */
                   1991: /*     dum=u; /\* Shifting c and u *\/ */
                   1992: /*     u = *cx; */
                   1993: /*     *cx = dum; */
                   1994: /*     dum = fu; */
                   1995: /*     fu = *fc; */
                   1996: /*     *fc =dum; */
                   1997: /*       } */
1.224     brouard  1998: #ifdef DEBUGMNBRAK
                   1999:                 double A, fparabu; 
                   2000:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2001:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2002:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2003:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2004: #endif
1.191     brouard  2005:       dum=u; /* Shifting c and u */
                   2006:       u = *cx;
                   2007:       *cx = dum;
                   2008:       dum = fu;
                   2009:       fu = *fc;
                   2010:       *fc =dum;
1.183     brouard  2011: #endif
1.162     brouard  2012:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2013: #ifdef DEBUG
1.224     brouard  2014:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2015:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2016: #endif
1.126     brouard  2017:       fu=(*func)(u); 
                   2018:       if (fu < *fc) { 
1.183     brouard  2019: #ifdef DEBUG
1.224     brouard  2020:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2021:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2022: #endif
                   2023:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2024:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2025: #ifdef DEBUG
                   2026:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2027: #endif
                   2028:       } 
1.162     brouard  2029:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2030: #ifdef DEBUG
1.224     brouard  2031:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2032:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2033: #endif
1.126     brouard  2034:       u=ulim; 
                   2035:       fu=(*func)(u); 
1.183     brouard  2036:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2037: #ifdef DEBUG
1.224     brouard  2038:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2039:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2040: #endif
1.126     brouard  2041:       u=(*cx)+GOLD*(*cx-*bx); 
                   2042:       fu=(*func)(u); 
1.224     brouard  2043: #ifdef DEBUG
                   2044:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2045:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2046: #endif
1.183     brouard  2047:     } /* end tests */
1.126     brouard  2048:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2049:     SHFT(*fa,*fb,*fc,fu) 
                   2050: #ifdef DEBUG
1.224     brouard  2051:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2052:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2053: #endif
                   2054:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2055: } 
                   2056: 
                   2057: /*************** linmin ************************/
1.162     brouard  2058: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2059: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2060: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2061: the value of func at the returned location p . This is actually all accomplished by calling the
                   2062: routines mnbrak and brent .*/
1.126     brouard  2063: int ncom; 
                   2064: double *pcom,*xicom;
                   2065: double (*nrfunc)(double []); 
                   2066:  
1.224     brouard  2067: #ifdef LINMINORIGINAL
1.126     brouard  2068: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2069: #else
                   2070: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2071: #endif
1.126     brouard  2072: { 
                   2073:   double brent(double ax, double bx, double cx, 
                   2074:               double (*f)(double), double tol, double *xmin); 
                   2075:   double f1dim(double x); 
                   2076:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2077:              double *fc, double (*func)(double)); 
                   2078:   int j; 
                   2079:   double xx,xmin,bx,ax; 
                   2080:   double fx,fb,fa;
1.187     brouard  2081: 
1.203     brouard  2082: #ifdef LINMINORIGINAL
                   2083: #else
                   2084:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2085: #endif
                   2086:   
1.126     brouard  2087:   ncom=n; 
                   2088:   pcom=vector(1,n); 
                   2089:   xicom=vector(1,n); 
                   2090:   nrfunc=func; 
                   2091:   for (j=1;j<=n;j++) { 
                   2092:     pcom[j]=p[j]; 
1.202     brouard  2093:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2094:   } 
1.187     brouard  2095: 
1.203     brouard  2096: #ifdef LINMINORIGINAL
                   2097:   xx=1.;
                   2098: #else
                   2099:   axs=0.0;
                   2100:   xxs=1.;
                   2101:   do{
                   2102:     xx= xxs;
                   2103: #endif
1.187     brouard  2104:     ax=0.;
                   2105:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2106:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2107:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2108:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2109:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2110:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2111:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2112: #ifdef LINMINORIGINAL
                   2113: #else
                   2114:     if (fx != fx){
1.224     brouard  2115:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2116:                        printf("|");
                   2117:                        fprintf(ficlog,"|");
1.203     brouard  2118: #ifdef DEBUGLINMIN
1.224     brouard  2119:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2120: #endif
                   2121:     }
1.224     brouard  2122:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2123: #endif
                   2124:   
1.191     brouard  2125: #ifdef DEBUGLINMIN
                   2126:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2127:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2128: #endif
1.224     brouard  2129: #ifdef LINMINORIGINAL
                   2130: #else
                   2131:        if(fb == fx){ /* Flat function in the direction */
                   2132:                xmin=xx;
                   2133:     *flat=1;
                   2134:        }else{
                   2135:     *flat=0;
                   2136: #endif
                   2137:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2138:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2139:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2140:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2141:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2142:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2143: #ifdef DEBUG
1.224     brouard  2144:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2145:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2146: #endif
                   2147: #ifdef LINMINORIGINAL
                   2148: #else
                   2149:                        }
1.126     brouard  2150: #endif
1.191     brouard  2151: #ifdef DEBUGLINMIN
                   2152:   printf("linmin end ");
1.202     brouard  2153:   fprintf(ficlog,"linmin end ");
1.191     brouard  2154: #endif
1.126     brouard  2155:   for (j=1;j<=n;j++) { 
1.203     brouard  2156: #ifdef LINMINORIGINAL
                   2157:     xi[j] *= xmin; 
                   2158: #else
                   2159: #ifdef DEBUGLINMIN
                   2160:     if(xxs <1.0)
                   2161:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2162: #endif
                   2163:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2164: #ifdef DEBUGLINMIN
                   2165:     if(xxs <1.0)
                   2166:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2167: #endif
                   2168: #endif
1.187     brouard  2169:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2170:   } 
1.191     brouard  2171: #ifdef DEBUGLINMIN
1.203     brouard  2172:   printf("\n");
1.191     brouard  2173:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2174:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2175:   for (j=1;j<=n;j++) { 
1.202     brouard  2176:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2177:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2178:     if(j % ncovmodel == 0){
1.191     brouard  2179:       printf("\n");
1.202     brouard  2180:       fprintf(ficlog,"\n");
                   2181:     }
1.191     brouard  2182:   }
1.203     brouard  2183: #else
1.191     brouard  2184: #endif
1.126     brouard  2185:   free_vector(xicom,1,n); 
                   2186:   free_vector(pcom,1,n); 
                   2187: } 
                   2188: 
                   2189: 
                   2190: /*************** powell ************************/
1.162     brouard  2191: /*
                   2192: Minimization of a function func of n variables. Input consists of an initial starting point
                   2193: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2194: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2195: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2196: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2197: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2198:  */
1.224     brouard  2199: #ifdef LINMINORIGINAL
                   2200: #else
                   2201:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2202:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2203: #endif
1.126     brouard  2204: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2205:            double (*func)(double [])) 
                   2206: { 
1.224     brouard  2207: #ifdef LINMINORIGINAL
                   2208:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2209:              double (*func)(double [])); 
1.224     brouard  2210: #else 
1.241     brouard  2211:  void linmin(double p[], double xi[], int n, double *fret,
                   2212:             double (*func)(double []),int *flat); 
1.224     brouard  2213: #endif
1.239     brouard  2214:  int i,ibig,j,jk,k; 
1.126     brouard  2215:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2216:   double directest;
1.126     brouard  2217:   double fp,fptt;
                   2218:   double *xits;
                   2219:   int niterf, itmp;
1.224     brouard  2220: #ifdef LINMINORIGINAL
                   2221: #else
                   2222: 
                   2223:   flatdir=ivector(1,n); 
                   2224:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2225: #endif
1.126     brouard  2226: 
                   2227:   pt=vector(1,n); 
                   2228:   ptt=vector(1,n); 
                   2229:   xit=vector(1,n); 
                   2230:   xits=vector(1,n); 
                   2231:   *fret=(*func)(p); 
                   2232:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2233:   rcurr_time = time(NULL);  
1.126     brouard  2234:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2235:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2236:     ibig=0; 
                   2237:     del=0.0; 
1.157     brouard  2238:     rlast_time=rcurr_time;
                   2239:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2240:     rcurr_time = time(NULL);  
                   2241:     curr_time = *localtime(&rcurr_time);
                   2242:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2243:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2244: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2245:     for (i=1;i<=n;i++) {
1.126     brouard  2246:       fprintf(ficrespow," %.12lf", p[i]);
                   2247:     }
1.239     brouard  2248:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2249:     printf("\n#model=  1      +     age ");
                   2250:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2251:     if(nagesqr==1){
1.241     brouard  2252:        printf("  + age*age  ");
                   2253:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2254:     }
                   2255:     for(j=1;j <=ncovmodel-2;j++){
                   2256:       if(Typevar[j]==0) {
                   2257:        printf("  +      V%d  ",Tvar[j]);
                   2258:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2259:       }else if(Typevar[j]==1) {
                   2260:        printf("  +    V%d*age ",Tvar[j]);
                   2261:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2262:       }else if(Typevar[j]==2) {
                   2263:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2264:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2265:       }
                   2266:     }
1.126     brouard  2267:     printf("\n");
1.239     brouard  2268: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2269: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2270:     fprintf(ficlog,"\n");
1.239     brouard  2271:     for(i=1,jk=1; i <=nlstate; i++){
                   2272:       for(k=1; k <=(nlstate+ndeath); k++){
                   2273:        if (k != i) {
                   2274:          printf("%d%d ",i,k);
                   2275:          fprintf(ficlog,"%d%d ",i,k);
                   2276:          for(j=1; j <=ncovmodel; j++){
                   2277:            printf("%12.7f ",p[jk]);
                   2278:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2279:            jk++; 
                   2280:          }
                   2281:          printf("\n");
                   2282:          fprintf(ficlog,"\n");
                   2283:        }
                   2284:       }
                   2285:     }
1.241     brouard  2286:     if(*iter <=3 && *iter >1){
1.157     brouard  2287:       tml = *localtime(&rcurr_time);
                   2288:       strcpy(strcurr,asctime(&tml));
                   2289:       rforecast_time=rcurr_time; 
1.126     brouard  2290:       itmp = strlen(strcurr);
                   2291:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2292:        strcurr[itmp-1]='\0';
1.162     brouard  2293:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2294:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2295:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2296:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2297:        forecast_time = *localtime(&rforecast_time);
                   2298:        strcpy(strfor,asctime(&forecast_time));
                   2299:        itmp = strlen(strfor);
                   2300:        if(strfor[itmp-1]=='\n')
                   2301:          strfor[itmp-1]='\0';
                   2302:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2303:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2304:       }
                   2305:     }
1.187     brouard  2306:     for (i=1;i<=n;i++) { /* For each direction i */
                   2307:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2308:       fptt=(*fret); 
                   2309: #ifdef DEBUG
1.203     brouard  2310:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2311:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2312: #endif
1.203     brouard  2313:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2314:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2315: #ifdef LINMINORIGINAL
1.188     brouard  2316:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2317: #else
                   2318:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2319:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2320: #endif
                   2321:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2322:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2323:                                /* because that direction will be replaced unless the gain del is small */
                   2324:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2325:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2326:                                /* with the new direction. */
                   2327:                                del=fabs(fptt-(*fret)); 
                   2328:                                ibig=i; 
1.126     brouard  2329:       } 
                   2330: #ifdef DEBUG
                   2331:       printf("%d %.12e",i,(*fret));
                   2332:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2333:       for (j=1;j<=n;j++) {
1.224     brouard  2334:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2335:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2336:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2337:       }
                   2338:       for(j=1;j<=n;j++) {
1.225     brouard  2339:                                printf(" p(%d)=%.12e",j,p[j]);
                   2340:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2341:       }
                   2342:       printf("\n");
                   2343:       fprintf(ficlog,"\n");
                   2344: #endif
1.187     brouard  2345:     } /* end loop on each direction i */
                   2346:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2347:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2348:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2349:       for(j=1;j<=n;j++) {
1.225     brouard  2350:                                if(flatdir[j] >0){
                   2351:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2352:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2353:                                }
                   2354:                                /* printf("\n"); */
                   2355:                                /* fprintf(ficlog,"\n"); */
                   2356:                        }
1.243     brouard  2357:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2358:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2359:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2360:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2361:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2362:       /* decreased of more than 3.84  */
                   2363:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2364:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2365:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2366:                        
1.188     brouard  2367:       /* Starting the program with initial values given by a former maximization will simply change */
                   2368:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2369:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2370:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2371: #ifdef DEBUG
                   2372:       int k[2],l;
                   2373:       k[0]=1;
                   2374:       k[1]=-1;
                   2375:       printf("Max: %.12e",(*func)(p));
                   2376:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2377:       for (j=1;j<=n;j++) {
                   2378:        printf(" %.12e",p[j]);
                   2379:        fprintf(ficlog," %.12e",p[j]);
                   2380:       }
                   2381:       printf("\n");
                   2382:       fprintf(ficlog,"\n");
                   2383:       for(l=0;l<=1;l++) {
                   2384:        for (j=1;j<=n;j++) {
                   2385:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2386:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2387:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2388:        }
                   2389:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2390:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2391:       }
                   2392: #endif
                   2393: 
1.224     brouard  2394: #ifdef LINMINORIGINAL
                   2395: #else
                   2396:       free_ivector(flatdir,1,n); 
                   2397: #endif
1.126     brouard  2398:       free_vector(xit,1,n); 
                   2399:       free_vector(xits,1,n); 
                   2400:       free_vector(ptt,1,n); 
                   2401:       free_vector(pt,1,n); 
                   2402:       return; 
1.192     brouard  2403:     } /* enough precision */ 
1.240     brouard  2404:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2405:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2406:       ptt[j]=2.0*p[j]-pt[j]; 
                   2407:       xit[j]=p[j]-pt[j]; 
                   2408:       pt[j]=p[j]; 
                   2409:     } 
1.181     brouard  2410:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2411: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2412:                if (*iter <=4) {
1.225     brouard  2413: #else
                   2414: #endif
1.224     brouard  2415: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2416: #else
1.161     brouard  2417:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2418: #endif
1.162     brouard  2419:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2420:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2421:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2422:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2423:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2424:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2425:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2426:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2427:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2428:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2429:       /* mu² and del² are equal when f3=f1 */
                   2430:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2431:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2432:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2433:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2434: #ifdef NRCORIGINAL
                   2435:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2436: #else
                   2437:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2438:       t= t- del*SQR(fp-fptt);
1.183     brouard  2439: #endif
1.202     brouard  2440:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2441: #ifdef DEBUG
1.181     brouard  2442:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2443:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2444:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2445:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2446:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2447:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2448:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2449:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2450: #endif
1.183     brouard  2451: #ifdef POWELLORIGINAL
                   2452:       if (t < 0.0) { /* Then we use it for new direction */
                   2453: #else
1.182     brouard  2454:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2455:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2456:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2457:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2458:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2459:       } 
1.181     brouard  2460:       if (directest < 0.0) { /* Then we use it for new direction */
                   2461: #endif
1.191     brouard  2462: #ifdef DEBUGLINMIN
1.234     brouard  2463:        printf("Before linmin in direction P%d-P0\n",n);
                   2464:        for (j=1;j<=n;j++) {
                   2465:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2466:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2467:          if(j % ncovmodel == 0){
                   2468:            printf("\n");
                   2469:            fprintf(ficlog,"\n");
                   2470:          }
                   2471:        }
1.224     brouard  2472: #endif
                   2473: #ifdef LINMINORIGINAL
1.234     brouard  2474:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2475: #else
1.234     brouard  2476:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2477:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2478: #endif
1.234     brouard  2479:        
1.191     brouard  2480: #ifdef DEBUGLINMIN
1.234     brouard  2481:        for (j=1;j<=n;j++) { 
                   2482:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2483:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2484:          if(j % ncovmodel == 0){
                   2485:            printf("\n");
                   2486:            fprintf(ficlog,"\n");
                   2487:          }
                   2488:        }
1.224     brouard  2489: #endif
1.234     brouard  2490:        for (j=1;j<=n;j++) { 
                   2491:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2492:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2493:        }
1.224     brouard  2494: #ifdef LINMINORIGINAL
                   2495: #else
1.234     brouard  2496:        for (j=1, flatd=0;j<=n;j++) {
                   2497:          if(flatdir[j]>0)
                   2498:            flatd++;
                   2499:        }
                   2500:        if(flatd >0){
1.255     brouard  2501:          printf("%d flat directions: ",flatd);
                   2502:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2503:          for (j=1;j<=n;j++) { 
                   2504:            if(flatdir[j]>0){
                   2505:              printf("%d ",j);
                   2506:              fprintf(ficlog,"%d ",j);
                   2507:            }
                   2508:          }
                   2509:          printf("\n");
                   2510:          fprintf(ficlog,"\n");
                   2511:        }
1.191     brouard  2512: #endif
1.234     brouard  2513:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2514:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2515:        
1.126     brouard  2516: #ifdef DEBUG
1.234     brouard  2517:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2518:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2519:        for(j=1;j<=n;j++){
                   2520:          printf(" %lf",xit[j]);
                   2521:          fprintf(ficlog," %lf",xit[j]);
                   2522:        }
                   2523:        printf("\n");
                   2524:        fprintf(ficlog,"\n");
1.126     brouard  2525: #endif
1.192     brouard  2526:       } /* end of t or directest negative */
1.224     brouard  2527: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2528: #else
1.234     brouard  2529:       } /* end if (fptt < fp)  */
1.192     brouard  2530: #endif
1.225     brouard  2531: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2532:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2533: #else
1.224     brouard  2534: #endif
1.234     brouard  2535:                } /* loop iteration */ 
1.126     brouard  2536: } 
1.234     brouard  2537:   
1.126     brouard  2538: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2539:   
1.235     brouard  2540:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2541:   {
1.279     brouard  2542:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2543:      *   (and selected quantitative values in nres)
                   2544:      *  by left multiplying the unit
                   2545:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2546:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2547:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2548:      * or prevalence in state 1, prevalence in state 2, 0
                   2549:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2550:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2551:      * Output is prlim.
                   2552:      * Initial matrix pimij 
                   2553:      */
1.206     brouard  2554:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2555:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2556:   /*  0,                   0                  , 1} */
                   2557:   /*
                   2558:    * and after some iteration: */
                   2559:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2560:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2561:   /*  0,                   0                  , 1} */
                   2562:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2563:   /* {0.51571254859325999, 0.4842874514067399, */
                   2564:   /*  0.51326036147820708, 0.48673963852179264} */
                   2565:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2566:     
1.126     brouard  2567:   int i, ii,j,k;
1.209     brouard  2568:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2569:   /* double **matprod2(); */ /* test */
1.218     brouard  2570:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2571:   double **newm;
1.209     brouard  2572:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2573:   int ncvloop=0;
1.169     brouard  2574:   
1.209     brouard  2575:   min=vector(1,nlstate);
                   2576:   max=vector(1,nlstate);
                   2577:   meandiff=vector(1,nlstate);
                   2578: 
1.218     brouard  2579:        /* Starting with matrix unity */
1.126     brouard  2580:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2581:     for (j=1;j<=nlstate+ndeath;j++){
                   2582:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2583:     }
1.169     brouard  2584:   
                   2585:   cov[1]=1.;
                   2586:   
                   2587:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2588:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2589:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2590:     ncvloop++;
1.126     brouard  2591:     newm=savm;
                   2592:     /* Covariates have to be included here again */
1.138     brouard  2593:     cov[2]=agefin;
1.187     brouard  2594:     if(nagesqr==1)
                   2595:       cov[3]= agefin*agefin;;
1.234     brouard  2596:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2597:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2598:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2599:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2600:     }
                   2601:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2602:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2603:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2604:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2605:     }
1.237     brouard  2606:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2607:       if(Dummy[Tvar[Tage[k]]]){
                   2608:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2609:       } else{
1.235     brouard  2610:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2611:       }
1.235     brouard  2612:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2613:     }
1.237     brouard  2614:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2615:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2616:       if(Dummy[Tvard[k][1]==0]){
                   2617:        if(Dummy[Tvard[k][2]==0]){
                   2618:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2619:        }else{
                   2620:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2621:        }
                   2622:       }else{
                   2623:        if(Dummy[Tvard[k][2]==0]){
                   2624:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2625:        }else{
                   2626:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2627:        }
                   2628:       }
1.234     brouard  2629:     }
1.138     brouard  2630:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2631:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2632:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2633:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2634:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2635:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2636:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2637:     
1.126     brouard  2638:     savm=oldm;
                   2639:     oldm=newm;
1.209     brouard  2640: 
                   2641:     for(j=1; j<=nlstate; j++){
                   2642:       max[j]=0.;
                   2643:       min[j]=1.;
                   2644:     }
                   2645:     for(i=1;i<=nlstate;i++){
                   2646:       sumnew=0;
                   2647:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2648:       for(j=1; j<=nlstate; j++){ 
                   2649:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2650:        max[j]=FMAX(max[j],prlim[i][j]);
                   2651:        min[j]=FMIN(min[j],prlim[i][j]);
                   2652:       }
                   2653:     }
                   2654: 
1.126     brouard  2655:     maxmax=0.;
1.209     brouard  2656:     for(j=1; j<=nlstate; j++){
                   2657:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2658:       maxmax=FMAX(maxmax,meandiff[j]);
                   2659:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2660:     } /* j loop */
1.203     brouard  2661:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2662:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2663:     if(maxmax < ftolpl){
1.209     brouard  2664:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2665:       free_vector(min,1,nlstate);
                   2666:       free_vector(max,1,nlstate);
                   2667:       free_vector(meandiff,1,nlstate);
1.126     brouard  2668:       return prlim;
                   2669:     }
1.169     brouard  2670:   } /* age loop */
1.208     brouard  2671:     /* After some age loop it doesn't converge */
1.209     brouard  2672:   printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.208     brouard  2673: Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
1.209     brouard  2674:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2675:   free_vector(min,1,nlstate);
                   2676:   free_vector(max,1,nlstate);
                   2677:   free_vector(meandiff,1,nlstate);
1.208     brouard  2678:   
1.169     brouard  2679:   return prlim; /* should not reach here */
1.126     brouard  2680: }
                   2681: 
1.217     brouard  2682: 
                   2683:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2684: 
1.218     brouard  2685:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2686:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2687:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2688: {
1.264     brouard  2689:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2690:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2691:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2692:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2693:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2694:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2695:   /* Initial matrix pimij */
                   2696:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2697:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2698:   /*  0,                   0                  , 1} */
                   2699:   /*
                   2700:    * and after some iteration: */
                   2701:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2702:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2703:   /*  0,                   0                  , 1} */
                   2704:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2705:   /* {0.51571254859325999, 0.4842874514067399, */
                   2706:   /*  0.51326036147820708, 0.48673963852179264} */
                   2707:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2708: 
                   2709:   int i, ii,j,k;
1.247     brouard  2710:   int first=0;
1.217     brouard  2711:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2712:   /* double **matprod2(); */ /* test */
                   2713:   double **out, cov[NCOVMAX+1], **bmij();
                   2714:   double **newm;
1.218     brouard  2715:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2716:   double        **oldm, **savm;  /* for use */
                   2717: 
1.217     brouard  2718:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2719:   int ncvloop=0;
                   2720:   
                   2721:   min=vector(1,nlstate);
                   2722:   max=vector(1,nlstate);
                   2723:   meandiff=vector(1,nlstate);
                   2724: 
1.266     brouard  2725:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2726:   oldm=oldms; savm=savms;
                   2727:   
                   2728:   /* Starting with matrix unity */
                   2729:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2730:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2731:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2732:     }
                   2733:   
                   2734:   cov[1]=1.;
                   2735:   
                   2736:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2737:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2738:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2739:   for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2740:     ncvloop++;
1.218     brouard  2741:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2742:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2743:     /* Covariates have to be included here again */
                   2744:     cov[2]=agefin;
                   2745:     if(nagesqr==1)
                   2746:       cov[3]= agefin*agefin;;
1.242     brouard  2747:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2748:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2749:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2750:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2751:     }
                   2752:     /* for (k=1; k<=cptcovn;k++) { */
                   2753:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2754:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2755:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2756:     /* } */
                   2757:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2758:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2759:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2760:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2761:     }
                   2762:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2763:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2764:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2765:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2766:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2767:       if(Dummy[Tvar[Tage[k]]]){
                   2768:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2769:       } else{
                   2770:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2771:       }
                   2772:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2773:     }
                   2774:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2775:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2776:       if(Dummy[Tvard[k][1]==0]){
                   2777:        if(Dummy[Tvard[k][2]==0]){
                   2778:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2779:        }else{
                   2780:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2781:        }
                   2782:       }else{
                   2783:        if(Dummy[Tvard[k][2]==0]){
                   2784:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2785:        }else{
                   2786:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2787:        }
                   2788:       }
1.217     brouard  2789:     }
                   2790:     
                   2791:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2792:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2793:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2794:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2795:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2796:                /* ij should be linked to the correct index of cov */
                   2797:                /* age and covariate values ij are in 'cov', but we need to pass
                   2798:                 * ij for the observed prevalence at age and status and covariate
                   2799:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2800:                 */
                   2801:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2802:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2803:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2804:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2805:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2806:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2807:     /*         printf("%d newm= ",i); */
                   2808:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2809:     /*           printf("%f ",newm[i][j]); */
                   2810:     /*         } */
                   2811:     /*         printf("oldm * "); */
                   2812:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2813:     /*           printf("%f ",oldm[i][j]); */
                   2814:     /*         } */
1.268     brouard  2815:     /*         printf(" bmmij "); */
1.266     brouard  2816:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2817:     /*           printf("%f ",pmmij[i][j]); */
                   2818:     /*         } */
                   2819:     /*         printf("\n"); */
                   2820:     /*   } */
                   2821:     /* } */
1.217     brouard  2822:     savm=oldm;
                   2823:     oldm=newm;
1.266     brouard  2824: 
1.217     brouard  2825:     for(j=1; j<=nlstate; j++){
                   2826:       max[j]=0.;
                   2827:       min[j]=1.;
                   2828:     }
                   2829:     for(j=1; j<=nlstate; j++){ 
                   2830:       for(i=1;i<=nlstate;i++){
1.234     brouard  2831:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2832:        bprlim[i][j]= newm[i][j];
                   2833:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2834:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2835:       }
                   2836:     }
1.218     brouard  2837:                
1.217     brouard  2838:     maxmax=0.;
                   2839:     for(i=1; i<=nlstate; i++){
                   2840:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2841:       maxmax=FMAX(maxmax,meandiff[i]);
                   2842:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2843:     } /* i loop */
1.217     brouard  2844:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2845:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2846:     if(maxmax < ftolpl){
1.220     brouard  2847:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2848:       free_vector(min,1,nlstate);
                   2849:       free_vector(max,1,nlstate);
                   2850:       free_vector(meandiff,1,nlstate);
                   2851:       return bprlim;
                   2852:     }
                   2853:   } /* age loop */
                   2854:     /* After some age loop it doesn't converge */
1.247     brouard  2855:   if(first){
                   2856:     first=1;
                   2857:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2858: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2859:   }
                   2860:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2861: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2862:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2863:   free_vector(min,1,nlstate);
                   2864:   free_vector(max,1,nlstate);
                   2865:   free_vector(meandiff,1,nlstate);
                   2866:   
                   2867:   return bprlim; /* should not reach here */
                   2868: }
                   2869: 
1.126     brouard  2870: /*************** transition probabilities ***************/ 
                   2871: 
                   2872: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2873: {
1.138     brouard  2874:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2875:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2876:      model to the ncovmodel covariates (including constant and age).
                   2877:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2878:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2879:      ncth covariate in the global vector x is given by the formula:
                   2880:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2881:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2882:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2883:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2884:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2885:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2886:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2887:   */
                   2888:   double s1, lnpijopii;
1.126     brouard  2889:   /*double t34;*/
1.164     brouard  2890:   int i,j, nc, ii, jj;
1.126     brouard  2891: 
1.223     brouard  2892:   for(i=1; i<= nlstate; i++){
                   2893:     for(j=1; j<i;j++){
                   2894:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2895:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2896:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2897:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2898:       }
                   2899:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2900:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2901:     }
                   2902:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2903:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2904:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2905:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2906:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2907:       }
                   2908:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2909:     }
                   2910:   }
1.218     brouard  2911:   
1.223     brouard  2912:   for(i=1; i<= nlstate; i++){
                   2913:     s1=0;
                   2914:     for(j=1; j<i; j++){
                   2915:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2916:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2917:     }
                   2918:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2919:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2920:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2921:     }
                   2922:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2923:     ps[i][i]=1./(s1+1.);
                   2924:     /* Computing other pijs */
                   2925:     for(j=1; j<i; j++)
                   2926:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2927:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2928:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2929:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2930:   } /* end i */
1.218     brouard  2931:   
1.223     brouard  2932:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2933:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2934:       ps[ii][jj]=0;
                   2935:       ps[ii][ii]=1;
                   2936:     }
                   2937:   }
1.218     brouard  2938:   
                   2939:   
1.223     brouard  2940:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2941:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2942:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2943:   /*   } */
                   2944:   /*   printf("\n "); */
                   2945:   /* } */
                   2946:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2947:   /*
                   2948:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2949:                goto end;*/
1.266     brouard  2950:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2951: }
                   2952: 
1.218     brouard  2953: /*************** backward transition probabilities ***************/ 
                   2954: 
                   2955:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2956: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2957:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2958: {
1.266     brouard  2959:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2960:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2961:    */
1.218     brouard  2962:   int i, ii, j,k;
1.222     brouard  2963:   
                   2964:   double **out, **pmij();
                   2965:   double sumnew=0.;
1.218     brouard  2966:   double agefin;
1.268     brouard  2967:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2968:   double **dnewm, **dsavm, **doldm;
                   2969:   double **bbmij;
                   2970:   
1.218     brouard  2971:   doldm=ddoldms; /* global pointers */
1.222     brouard  2972:   dnewm=ddnewms;
                   2973:   dsavm=ddsavms;
                   2974:   
                   2975:   agefin=cov[2];
1.268     brouard  2976:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2977:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2978:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2979:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2980: 
                   2981:   /* P_x */
1.266     brouard  2982:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2983:   /* outputs pmmij which is a stochastic matrix in row */
                   2984: 
                   2985:   /* Diag(w_x) */
                   2986:   /* Problem with prevacurrent which can be zero */
                   2987:   sumnew=0.;
1.269     brouard  2988:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  2989:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  2990:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  2991:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   2992:   }
                   2993:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   2994:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   2995:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  2996:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  2997:     }
                   2998:   }else{
                   2999:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3000:       for (j=1;j<=nlstate+ndeath;j++)
                   3001:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3002:     }
                   3003:     /* if(sumnew <0.9){ */
                   3004:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3005:     /* } */
                   3006:   }
                   3007:   k3=0.0;  /* We put the last diagonal to 0 */
                   3008:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3009:       doldm[ii][ii]= k3;
                   3010:   }
                   3011:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3012:   
                   3013:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   3014:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   3015: 
                   3016:   /* Diag(Sum_i w^i_x p^ij_x */
                   3017:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3018:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3019:     sumnew=0.;
1.222     brouard  3020:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3021:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3022:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3023:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3024:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3025:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3026:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3027:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3028:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3029:        /* }else */
1.268     brouard  3030:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3031:     } /*End ii */
                   3032:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3033: 
                   3034:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   3035:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3036:   /* end bmij */
1.266     brouard  3037:   return ps; /*pointer is unchanged */
1.218     brouard  3038: }
1.217     brouard  3039: /*************** transition probabilities ***************/ 
                   3040: 
1.218     brouard  3041: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3042: {
                   3043:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3044:      computes the probability to be observed in state j being in state i by appying the
                   3045:      model to the ncovmodel covariates (including constant and age).
                   3046:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3047:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3048:      ncth covariate in the global vector x is given by the formula:
                   3049:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3050:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3051:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3052:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3053:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3054:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3055:   */
                   3056:   double s1, lnpijopii;
                   3057:   /*double t34;*/
                   3058:   int i,j, nc, ii, jj;
                   3059: 
1.234     brouard  3060:   for(i=1; i<= nlstate; i++){
                   3061:     for(j=1; j<i;j++){
                   3062:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3063:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3064:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3065:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3066:       }
                   3067:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3068:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3069:     }
                   3070:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3071:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3072:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3073:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3074:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3075:       }
                   3076:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3077:     }
                   3078:   }
                   3079:   
                   3080:   for(i=1; i<= nlstate; i++){
                   3081:     s1=0;
                   3082:     for(j=1; j<i; j++){
                   3083:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3084:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3085:     }
                   3086:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3087:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3088:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3089:     }
                   3090:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3091:     ps[i][i]=1./(s1+1.);
                   3092:     /* Computing other pijs */
                   3093:     for(j=1; j<i; j++)
                   3094:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3095:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3096:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3097:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3098:   } /* end i */
                   3099:   
                   3100:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3101:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3102:       ps[ii][jj]=0;
                   3103:       ps[ii][ii]=1;
                   3104:     }
                   3105:   }
                   3106:   /* Added for backcast */ /* Transposed matrix too */
                   3107:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3108:     s1=0.;
                   3109:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3110:       s1+=ps[ii][jj];
                   3111:     }
                   3112:     for(ii=1; ii<= nlstate; ii++){
                   3113:       ps[ii][jj]=ps[ii][jj]/s1;
                   3114:     }
                   3115:   }
                   3116:   /* Transposition */
                   3117:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3118:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3119:       s1=ps[ii][jj];
                   3120:       ps[ii][jj]=ps[jj][ii];
                   3121:       ps[jj][ii]=s1;
                   3122:     }
                   3123:   }
                   3124:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3125:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3126:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3127:   /*   } */
                   3128:   /*   printf("\n "); */
                   3129:   /* } */
                   3130:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3131:   /*
                   3132:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3133:     goto end;*/
                   3134:   return ps;
1.217     brouard  3135: }
                   3136: 
                   3137: 
1.126     brouard  3138: /**************** Product of 2 matrices ******************/
                   3139: 
1.145     brouard  3140: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3141: {
                   3142:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3143:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3144:   /* in, b, out are matrice of pointers which should have been initialized 
                   3145:      before: only the contents of out is modified. The function returns
                   3146:      a pointer to pointers identical to out */
1.145     brouard  3147:   int i, j, k;
1.126     brouard  3148:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3149:     for(k=ncolol; k<=ncoloh; k++){
                   3150:       out[i][k]=0.;
                   3151:       for(j=ncl; j<=nch; j++)
                   3152:        out[i][k] +=in[i][j]*b[j][k];
                   3153:     }
1.126     brouard  3154:   return out;
                   3155: }
                   3156: 
                   3157: 
                   3158: /************* Higher Matrix Product ***************/
                   3159: 
1.235     brouard  3160: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3161: {
1.218     brouard  3162:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3163:      'nhstepm*hstepm*stepm' months (i.e. until
                   3164:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3165:      nhstepm*hstepm matrices. 
                   3166:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3167:      (typically every 2 years instead of every month which is too big 
                   3168:      for the memory).
                   3169:      Model is determined by parameters x and covariates have to be 
                   3170:      included manually here. 
                   3171: 
                   3172:      */
                   3173: 
                   3174:   int i, j, d, h, k;
1.131     brouard  3175:   double **out, cov[NCOVMAX+1];
1.126     brouard  3176:   double **newm;
1.187     brouard  3177:   double agexact;
1.214     brouard  3178:   double agebegin, ageend;
1.126     brouard  3179: 
                   3180:   /* Hstepm could be zero and should return the unit matrix */
                   3181:   for (i=1;i<=nlstate+ndeath;i++)
                   3182:     for (j=1;j<=nlstate+ndeath;j++){
                   3183:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3184:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3185:     }
                   3186:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3187:   for(h=1; h <=nhstepm; h++){
                   3188:     for(d=1; d <=hstepm; d++){
                   3189:       newm=savm;
                   3190:       /* Covariates have to be included here again */
                   3191:       cov[1]=1.;
1.214     brouard  3192:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3193:       cov[2]=agexact;
                   3194:       if(nagesqr==1)
1.227     brouard  3195:        cov[3]= agexact*agexact;
1.235     brouard  3196:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3197:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3198:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3199:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3200:       }
                   3201:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3202:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3203:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3204:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3205:       }
                   3206:       for (k=1; k<=cptcovage;k++){
                   3207:        if(Dummy[Tvar[Tage[k]]]){
                   3208:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3209:        } else{
                   3210:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3211:        }
                   3212:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3213:       }
                   3214:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3215:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3216:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3217:       }
                   3218:       /* for (k=1; k<=cptcovn;k++)  */
                   3219:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3220:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3221:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3222:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3223:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3224:       
                   3225:       
1.126     brouard  3226:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3227:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3228:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3229:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3230:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3231:       /* if((int)age == 70){ */
                   3232:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3233:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3234:       /*         printf("%d pmmij ",i); */
                   3235:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3236:       /*           printf("%f ",pmmij[i][j]); */
                   3237:       /*         } */
                   3238:       /*         printf(" oldm "); */
                   3239:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3240:       /*           printf("%f ",oldm[i][j]); */
                   3241:       /*         } */
                   3242:       /*         printf("\n"); */
                   3243:       /*       } */
                   3244:       /* } */
1.126     brouard  3245:       savm=oldm;
                   3246:       oldm=newm;
                   3247:     }
                   3248:     for(i=1; i<=nlstate+ndeath; i++)
                   3249:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3250:        po[i][j][h]=newm[i][j];
                   3251:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3252:       }
1.128     brouard  3253:     /*printf("h=%d ",h);*/
1.126     brouard  3254:   } /* end h */
1.267     brouard  3255:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3256:   return po;
                   3257: }
                   3258: 
1.217     brouard  3259: /************* Higher Back Matrix Product ***************/
1.218     brouard  3260: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3261: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3262: {
1.266     brouard  3263:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3264:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3265:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3266:      nhstepm*hstepm matrices.
                   3267:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3268:      (typically every 2 years instead of every month which is too big
1.217     brouard  3269:      for the memory).
1.218     brouard  3270:      Model is determined by parameters x and covariates have to be
1.266     brouard  3271:      included manually here. Then we use a call to bmij(x and cov)
                   3272:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3273:   */
1.217     brouard  3274: 
                   3275:   int i, j, d, h, k;
1.266     brouard  3276:   double **out, cov[NCOVMAX+1], **bmij();
                   3277:   double **newm, ***newmm;
1.217     brouard  3278:   double agexact;
                   3279:   double agebegin, ageend;
1.222     brouard  3280:   double **oldm, **savm;
1.217     brouard  3281: 
1.266     brouard  3282:   newmm=po; /* To be saved */
                   3283:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3284:   /* Hstepm could be zero and should return the unit matrix */
                   3285:   for (i=1;i<=nlstate+ndeath;i++)
                   3286:     for (j=1;j<=nlstate+ndeath;j++){
                   3287:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3288:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3289:     }
                   3290:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3291:   for(h=1; h <=nhstepm; h++){
                   3292:     for(d=1; d <=hstepm; d++){
                   3293:       newm=savm;
                   3294:       /* Covariates have to be included here again */
                   3295:       cov[1]=1.;
1.271     brouard  3296:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3297:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3298:       cov[2]=agexact;
                   3299:       if(nagesqr==1)
1.222     brouard  3300:        cov[3]= agexact*agexact;
1.266     brouard  3301:       for (k=1; k<=cptcovn;k++){
                   3302:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3303:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3304:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3305:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3306:       }
1.267     brouard  3307:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3308:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3309:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3310:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3311:       }
                   3312:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3313:        if(Dummy[Tvar[Tage[k]]]){
                   3314:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3315:        } else{
                   3316:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3317:        }
                   3318:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3319:       }
                   3320:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3321:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3322:       }                        
1.217     brouard  3323:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3324:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3325: 
1.218     brouard  3326:       /* Careful transposed matrix */
1.266     brouard  3327:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3328:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3329:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3330:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3331:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3332:       /* if((int)age == 70){ */
                   3333:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3334:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3335:       /*         printf("%d pmmij ",i); */
                   3336:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3337:       /*           printf("%f ",pmmij[i][j]); */
                   3338:       /*         } */
                   3339:       /*         printf(" oldm "); */
                   3340:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3341:       /*           printf("%f ",oldm[i][j]); */
                   3342:       /*         } */
                   3343:       /*         printf("\n"); */
                   3344:       /*       } */
                   3345:       /* } */
                   3346:       savm=oldm;
                   3347:       oldm=newm;
                   3348:     }
                   3349:     for(i=1; i<=nlstate+ndeath; i++)
                   3350:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3351:        po[i][j][h]=newm[i][j];
1.268     brouard  3352:        /* if(h==nhstepm) */
                   3353:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3354:       }
1.268     brouard  3355:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3356:   } /* end h */
1.268     brouard  3357:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3358:   return po;
                   3359: }
                   3360: 
                   3361: 
1.162     brouard  3362: #ifdef NLOPT
                   3363:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3364:   double fret;
                   3365:   double *xt;
                   3366:   int j;
                   3367:   myfunc_data *d2 = (myfunc_data *) pd;
                   3368: /* xt = (p1-1); */
                   3369:   xt=vector(1,n); 
                   3370:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3371: 
                   3372:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3373:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3374:   printf("Function = %.12lf ",fret);
                   3375:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3376:   printf("\n");
                   3377:  free_vector(xt,1,n);
                   3378:   return fret;
                   3379: }
                   3380: #endif
1.126     brouard  3381: 
                   3382: /*************** log-likelihood *************/
                   3383: double func( double *x)
                   3384: {
1.226     brouard  3385:   int i, ii, j, k, mi, d, kk;
                   3386:   int ioffset=0;
                   3387:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3388:   double **out;
                   3389:   double lli; /* Individual log likelihood */
                   3390:   int s1, s2;
1.228     brouard  3391:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3392:   double bbh, survp;
                   3393:   long ipmx;
                   3394:   double agexact;
                   3395:   /*extern weight */
                   3396:   /* We are differentiating ll according to initial status */
                   3397:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3398:   /*for(i=1;i<imx;i++) 
                   3399:     printf(" %d\n",s[4][i]);
                   3400:   */
1.162     brouard  3401: 
1.226     brouard  3402:   ++countcallfunc;
1.162     brouard  3403: 
1.226     brouard  3404:   cov[1]=1.;
1.126     brouard  3405: 
1.226     brouard  3406:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3407:   ioffset=0;
1.226     brouard  3408:   if(mle==1){
                   3409:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3410:       /* Computes the values of the ncovmodel covariates of the model
                   3411:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3412:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3413:         to be observed in j being in i according to the model.
                   3414:       */
1.243     brouard  3415:       ioffset=2+nagesqr ;
1.233     brouard  3416:    /* Fixed */
1.234     brouard  3417:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3418:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3419:       }
1.226     brouard  3420:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3421:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3422:         has been calculated etc */
                   3423:       /* For an individual i, wav[i] gives the number of effective waves */
                   3424:       /* We compute the contribution to Likelihood of each effective transition
                   3425:         mw[mi][i] is real wave of the mi th effectve wave */
                   3426:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3427:         s2=s[mw[mi+1][i]][i];
                   3428:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3429:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3430:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3431:       */
                   3432:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3433:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3434:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3435:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3436:        }
                   3437:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3438:          for (j=1;j<=nlstate+ndeath;j++){
                   3439:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3440:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3441:          }
                   3442:        for(d=0; d<dh[mi][i]; d++){
                   3443:          newm=savm;
                   3444:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3445:          cov[2]=agexact;
                   3446:          if(nagesqr==1)
                   3447:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3448:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3449:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3450:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3451:          else
                   3452:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3453:          }
                   3454:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3455:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3456:          savm=oldm;
                   3457:          oldm=newm;
                   3458:        } /* end mult */
                   3459:        
                   3460:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3461:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3462:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3463:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3464:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3465:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3466:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3467:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3468:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3469:                                 * -stepm/2 to stepm/2 .
                   3470:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3471:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3472:                                 */
1.234     brouard  3473:        s1=s[mw[mi][i]][i];
                   3474:        s2=s[mw[mi+1][i]][i];
                   3475:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3476:        /* bias bh is positive if real duration
                   3477:         * is higher than the multiple of stepm and negative otherwise.
                   3478:         */
                   3479:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3480:        if( s2 > nlstate){ 
                   3481:          /* i.e. if s2 is a death state and if the date of death is known 
                   3482:             then the contribution to the likelihood is the probability to 
                   3483:             die between last step unit time and current  step unit time, 
                   3484:             which is also equal to probability to die before dh 
                   3485:             minus probability to die before dh-stepm . 
                   3486:             In version up to 0.92 likelihood was computed
                   3487:             as if date of death was unknown. Death was treated as any other
                   3488:             health state: the date of the interview describes the actual state
                   3489:             and not the date of a change in health state. The former idea was
                   3490:             to consider that at each interview the state was recorded
                   3491:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3492:             introduced the exact date of death then we should have modified
                   3493:             the contribution of an exact death to the likelihood. This new
                   3494:             contribution is smaller and very dependent of the step unit
                   3495:             stepm. It is no more the probability to die between last interview
                   3496:             and month of death but the probability to survive from last
                   3497:             interview up to one month before death multiplied by the
                   3498:             probability to die within a month. Thanks to Chris
                   3499:             Jackson for correcting this bug.  Former versions increased
                   3500:             mortality artificially. The bad side is that we add another loop
                   3501:             which slows down the processing. The difference can be up to 10%
                   3502:             lower mortality.
                   3503:          */
                   3504:          /* If, at the beginning of the maximization mostly, the
                   3505:             cumulative probability or probability to be dead is
                   3506:             constant (ie = 1) over time d, the difference is equal to
                   3507:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3508:             s1 at precedent wave, to be dead a month before current
                   3509:             wave is equal to probability, being at state s1 at
                   3510:             precedent wave, to be dead at mont of the current
                   3511:             wave. Then the observed probability (that this person died)
                   3512:             is null according to current estimated parameter. In fact,
                   3513:             it should be very low but not zero otherwise the log go to
                   3514:             infinity.
                   3515:          */
1.183     brouard  3516: /* #ifdef INFINITYORIGINAL */
                   3517: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3518: /* #else */
                   3519: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3520: /*         lli=log(mytinydouble); */
                   3521: /*       else */
                   3522: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3523: /* #endif */
1.226     brouard  3524:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3525:          
1.226     brouard  3526:        } else if  ( s2==-1 ) { /* alive */
                   3527:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3528:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3529:          /*survp += out[s1][j]; */
                   3530:          lli= log(survp);
                   3531:        }
                   3532:        else if  (s2==-4) { 
                   3533:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3534:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3535:          lli= log(survp); 
                   3536:        } 
                   3537:        else if  (s2==-5) { 
                   3538:          for (j=1,survp=0. ; j<=2; j++)  
                   3539:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3540:          lli= log(survp); 
                   3541:        } 
                   3542:        else{
                   3543:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3544:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3545:        } 
                   3546:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3547:        /*if(lli ==000.0)*/
                   3548:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3549:        ipmx +=1;
                   3550:        sw += weight[i];
                   3551:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3552:        /* if (lli < log(mytinydouble)){ */
                   3553:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3554:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3555:        /* } */
                   3556:       } /* end of wave */
                   3557:     } /* end of individual */
                   3558:   }  else if(mle==2){
                   3559:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3560:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3561:       for(mi=1; mi<= wav[i]-1; mi++){
                   3562:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3563:          for (j=1;j<=nlstate+ndeath;j++){
                   3564:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3565:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3566:          }
                   3567:        for(d=0; d<=dh[mi][i]; d++){
                   3568:          newm=savm;
                   3569:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3570:          cov[2]=agexact;
                   3571:          if(nagesqr==1)
                   3572:            cov[3]= agexact*agexact;
                   3573:          for (kk=1; kk<=cptcovage;kk++) {
                   3574:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3575:          }
                   3576:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3577:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3578:          savm=oldm;
                   3579:          oldm=newm;
                   3580:        } /* end mult */
                   3581:       
                   3582:        s1=s[mw[mi][i]][i];
                   3583:        s2=s[mw[mi+1][i]][i];
                   3584:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3585:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3586:        ipmx +=1;
                   3587:        sw += weight[i];
                   3588:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3589:       } /* end of wave */
                   3590:     } /* end of individual */
                   3591:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3592:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3593:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3594:       for(mi=1; mi<= wav[i]-1; mi++){
                   3595:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3596:          for (j=1;j<=nlstate+ndeath;j++){
                   3597:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3598:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3599:          }
                   3600:        for(d=0; d<dh[mi][i]; d++){
                   3601:          newm=savm;
                   3602:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3603:          cov[2]=agexact;
                   3604:          if(nagesqr==1)
                   3605:            cov[3]= agexact*agexact;
                   3606:          for (kk=1; kk<=cptcovage;kk++) {
                   3607:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3608:          }
                   3609:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3610:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3611:          savm=oldm;
                   3612:          oldm=newm;
                   3613:        } /* end mult */
                   3614:       
                   3615:        s1=s[mw[mi][i]][i];
                   3616:        s2=s[mw[mi+1][i]][i];
                   3617:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3618:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3619:        ipmx +=1;
                   3620:        sw += weight[i];
                   3621:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3622:       } /* end of wave */
                   3623:     } /* end of individual */
                   3624:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3625:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3626:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3627:       for(mi=1; mi<= wav[i]-1; mi++){
                   3628:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3629:          for (j=1;j<=nlstate+ndeath;j++){
                   3630:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3631:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3632:          }
                   3633:        for(d=0; d<dh[mi][i]; d++){
                   3634:          newm=savm;
                   3635:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3636:          cov[2]=agexact;
                   3637:          if(nagesqr==1)
                   3638:            cov[3]= agexact*agexact;
                   3639:          for (kk=1; kk<=cptcovage;kk++) {
                   3640:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3641:          }
1.126     brouard  3642:        
1.226     brouard  3643:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3644:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3645:          savm=oldm;
                   3646:          oldm=newm;
                   3647:        } /* end mult */
                   3648:       
                   3649:        s1=s[mw[mi][i]][i];
                   3650:        s2=s[mw[mi+1][i]][i];
                   3651:        if( s2 > nlstate){ 
                   3652:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3653:        } else if  ( s2==-1 ) { /* alive */
                   3654:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3655:            survp += out[s1][j];
                   3656:          lli= log(survp);
                   3657:        }else{
                   3658:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3659:        }
                   3660:        ipmx +=1;
                   3661:        sw += weight[i];
                   3662:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3663: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3664:       } /* end of wave */
                   3665:     } /* end of individual */
                   3666:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3667:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3668:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3669:       for(mi=1; mi<= wav[i]-1; mi++){
                   3670:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3671:          for (j=1;j<=nlstate+ndeath;j++){
                   3672:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3673:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3674:          }
                   3675:        for(d=0; d<dh[mi][i]; d++){
                   3676:          newm=savm;
                   3677:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3678:          cov[2]=agexact;
                   3679:          if(nagesqr==1)
                   3680:            cov[3]= agexact*agexact;
                   3681:          for (kk=1; kk<=cptcovage;kk++) {
                   3682:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3683:          }
1.126     brouard  3684:        
1.226     brouard  3685:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3686:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3687:          savm=oldm;
                   3688:          oldm=newm;
                   3689:        } /* end mult */
                   3690:       
                   3691:        s1=s[mw[mi][i]][i];
                   3692:        s2=s[mw[mi+1][i]][i];
                   3693:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3694:        ipmx +=1;
                   3695:        sw += weight[i];
                   3696:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3697:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3698:       } /* end of wave */
                   3699:     } /* end of individual */
                   3700:   } /* End of if */
                   3701:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3702:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3703:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3704:   return -l;
1.126     brouard  3705: }
                   3706: 
                   3707: /*************** log-likelihood *************/
                   3708: double funcone( double *x)
                   3709: {
1.228     brouard  3710:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3711:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3712:   int ioffset=0;
1.131     brouard  3713:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3714:   double **out;
                   3715:   double lli; /* Individual log likelihood */
                   3716:   double llt;
                   3717:   int s1, s2;
1.228     brouard  3718:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3719: 
1.126     brouard  3720:   double bbh, survp;
1.187     brouard  3721:   double agexact;
1.214     brouard  3722:   double agebegin, ageend;
1.126     brouard  3723:   /*extern weight */
                   3724:   /* We are differentiating ll according to initial status */
                   3725:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3726:   /*for(i=1;i<imx;i++) 
                   3727:     printf(" %d\n",s[4][i]);
                   3728:   */
                   3729:   cov[1]=1.;
                   3730: 
                   3731:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3732:   ioffset=0;
                   3733:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3734:     /* ioffset=2+nagesqr+cptcovage; */
                   3735:     ioffset=2+nagesqr;
1.232     brouard  3736:     /* Fixed */
1.224     brouard  3737:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3738:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3739:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3740:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3741: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3742: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3743: /*    cov[2+6]=covar[2][i]; V2  */
                   3744: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3745: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3746: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3747: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3748: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3749: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3750:     }
1.232     brouard  3751:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3752:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3753:     /* } */
1.231     brouard  3754:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3755:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3756:     /* } */
1.225     brouard  3757:     
1.233     brouard  3758: 
                   3759:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3760:     /* Wave varying (but not age varying) */
                   3761:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3762:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3763:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3764:       }
1.232     brouard  3765:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3766:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3767:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3768:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3769:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3770:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3771:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3772:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3773:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3774:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3775:       /* } */
1.126     brouard  3776:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3777:        for (j=1;j<=nlstate+ndeath;j++){
                   3778:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3779:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3780:        }
1.214     brouard  3781:       
                   3782:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3783:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3784:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3785:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3786:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3787:          and mw[mi+1][i]. dh depends on stepm.*/
                   3788:        newm=savm;
1.247     brouard  3789:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3790:        cov[2]=agexact;
                   3791:        if(nagesqr==1)
                   3792:          cov[3]= agexact*agexact;
                   3793:        for (kk=1; kk<=cptcovage;kk++) {
                   3794:          if(!FixedV[Tvar[Tage[kk]]])
                   3795:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3796:          else
                   3797:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3798:        }
                   3799:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3800:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3801:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3802:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3803:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3804:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3805:        savm=oldm;
                   3806:        oldm=newm;
1.126     brouard  3807:       } /* end mult */
                   3808:       
                   3809:       s1=s[mw[mi][i]][i];
                   3810:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3811:       /* if(s2==-1){ */
1.268     brouard  3812:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3813:       /*       /\* exit(1); *\/ */
                   3814:       /* } */
1.126     brouard  3815:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3816:       /* bias is positive if real duration
                   3817:        * is higher than the multiple of stepm and negative otherwise.
                   3818:        */
                   3819:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3820:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3821:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3822:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3823:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3824:        lli= log(survp);
1.126     brouard  3825:       }else if (mle==1){
1.242     brouard  3826:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3827:       } else if(mle==2){
1.242     brouard  3828:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3829:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3830:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3831:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3832:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3833:       } else{  /* mle=0 back to 1 */
1.242     brouard  3834:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3835:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3836:       } /* End of if */
                   3837:       ipmx +=1;
                   3838:       sw += weight[i];
                   3839:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3840:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3841:       if(globpr){
1.246     brouard  3842:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3843:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3844:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3845:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3846:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3847:          llt +=ll[k]*gipmx/gsw;
                   3848:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3849:        }
                   3850:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3851:       }
1.232     brouard  3852:        } /* end of wave */
                   3853: } /* end of individual */
                   3854: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3855: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3856: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3857: if(globpr==0){ /* First time we count the contributions and weights */
                   3858:        gipmx=ipmx;
                   3859:        gsw=sw;
                   3860: }
                   3861: return -l;
1.126     brouard  3862: }
                   3863: 
                   3864: 
                   3865: /*************** function likelione ***********/
                   3866: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3867: {
                   3868:   /* This routine should help understanding what is done with 
                   3869:      the selection of individuals/waves and
                   3870:      to check the exact contribution to the likelihood.
                   3871:      Plotting could be done.
                   3872:    */
                   3873:   int k;
                   3874: 
                   3875:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3876:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3877:     strcat(fileresilk,fileresu);
1.126     brouard  3878:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3879:       printf("Problem with resultfile: %s\n", fileresilk);
                   3880:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3881:     }
1.214     brouard  3882:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3883:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3884:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3885:     for(k=1; k<=nlstate; k++) 
                   3886:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3887:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3888:   }
                   3889: 
                   3890:   *fretone=(*funcone)(p);
                   3891:   if(*globpri !=0){
                   3892:     fclose(ficresilk);
1.205     brouard  3893:     if (mle ==0)
                   3894:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3895:     else if(mle >=1)
                   3896:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3897:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3898:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3899:       
                   3900:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3901:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3902: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3903:     }
1.207     brouard  3904:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3905: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3906:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3907: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3908:     fflush(fichtm);
1.205     brouard  3909:   }
1.126     brouard  3910:   return;
                   3911: }
                   3912: 
                   3913: 
                   3914: /*********** Maximum Likelihood Estimation ***************/
                   3915: 
                   3916: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3917: {
1.165     brouard  3918:   int i,j, iter=0;
1.126     brouard  3919:   double **xi;
                   3920:   double fret;
                   3921:   double fretone; /* Only one call to likelihood */
                   3922:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3923: 
                   3924: #ifdef NLOPT
                   3925:   int creturn;
                   3926:   nlopt_opt opt;
                   3927:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3928:   double *lb;
                   3929:   double minf; /* the minimum objective value, upon return */
                   3930:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3931:   myfunc_data dinst, *d = &dinst;
                   3932: #endif
                   3933: 
                   3934: 
1.126     brouard  3935:   xi=matrix(1,npar,1,npar);
                   3936:   for (i=1;i<=npar;i++)
                   3937:     for (j=1;j<=npar;j++)
                   3938:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3939:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3940:   strcpy(filerespow,"POW_"); 
1.126     brouard  3941:   strcat(filerespow,fileres);
                   3942:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3943:     printf("Problem with resultfile: %s\n", filerespow);
                   3944:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3945:   }
                   3946:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3947:   for (i=1;i<=nlstate;i++)
                   3948:     for(j=1;j<=nlstate+ndeath;j++)
                   3949:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3950:   fprintf(ficrespow,"\n");
1.162     brouard  3951: #ifdef POWELL
1.126     brouard  3952:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3953: #endif
1.126     brouard  3954: 
1.162     brouard  3955: #ifdef NLOPT
                   3956: #ifdef NEWUOA
                   3957:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3958: #else
                   3959:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3960: #endif
                   3961:   lb=vector(0,npar-1);
                   3962:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3963:   nlopt_set_lower_bounds(opt, lb);
                   3964:   nlopt_set_initial_step1(opt, 0.1);
                   3965:   
                   3966:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3967:   d->function = func;
                   3968:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3969:   nlopt_set_min_objective(opt, myfunc, d);
                   3970:   nlopt_set_xtol_rel(opt, ftol);
                   3971:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3972:     printf("nlopt failed! %d\n",creturn); 
                   3973:   }
                   3974:   else {
                   3975:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3976:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3977:     iter=1; /* not equal */
                   3978:   }
                   3979:   nlopt_destroy(opt);
                   3980: #endif
1.126     brouard  3981:   free_matrix(xi,1,npar,1,npar);
                   3982:   fclose(ficrespow);
1.203     brouard  3983:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3984:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3985:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3986: 
                   3987: }
                   3988: 
                   3989: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  3990: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  3991: {
                   3992:   double  **a,**y,*x,pd;
1.203     brouard  3993:   /* double **hess; */
1.164     brouard  3994:   int i, j;
1.126     brouard  3995:   int *indx;
                   3996: 
                   3997:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  3998:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  3999:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4000:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4001:   double gompertz(double p[]);
1.203     brouard  4002:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4003: 
                   4004:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4005:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4006:   for (i=1;i<=npar;i++){
1.203     brouard  4007:     printf("%d-",i);fflush(stdout);
                   4008:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4009:    
                   4010:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4011:     
                   4012:     /*  printf(" %f ",p[i]);
                   4013:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4014:   }
                   4015:   
                   4016:   for (i=1;i<=npar;i++) {
                   4017:     for (j=1;j<=npar;j++)  {
                   4018:       if (j>i) { 
1.203     brouard  4019:        printf(".%d-%d",i,j);fflush(stdout);
                   4020:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4021:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4022:        
                   4023:        hess[j][i]=hess[i][j];    
                   4024:        /*printf(" %lf ",hess[i][j]);*/
                   4025:       }
                   4026:     }
                   4027:   }
                   4028:   printf("\n");
                   4029:   fprintf(ficlog,"\n");
                   4030: 
                   4031:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4032:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4033:   
                   4034:   a=matrix(1,npar,1,npar);
                   4035:   y=matrix(1,npar,1,npar);
                   4036:   x=vector(1,npar);
                   4037:   indx=ivector(1,npar);
                   4038:   for (i=1;i<=npar;i++)
                   4039:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4040:   ludcmp(a,npar,indx,&pd);
                   4041: 
                   4042:   for (j=1;j<=npar;j++) {
                   4043:     for (i=1;i<=npar;i++) x[i]=0;
                   4044:     x[j]=1;
                   4045:     lubksb(a,npar,indx,x);
                   4046:     for (i=1;i<=npar;i++){ 
                   4047:       matcov[i][j]=x[i];
                   4048:     }
                   4049:   }
                   4050: 
                   4051:   printf("\n#Hessian matrix#\n");
                   4052:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4053:   for (i=1;i<=npar;i++) { 
                   4054:     for (j=1;j<=npar;j++) { 
1.203     brouard  4055:       printf("%.6e ",hess[i][j]);
                   4056:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4057:     }
                   4058:     printf("\n");
                   4059:     fprintf(ficlog,"\n");
                   4060:   }
                   4061: 
1.203     brouard  4062:   /* printf("\n#Covariance matrix#\n"); */
                   4063:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4064:   /* for (i=1;i<=npar;i++) {  */
                   4065:   /*   for (j=1;j<=npar;j++) {  */
                   4066:   /*     printf("%.6e ",matcov[i][j]); */
                   4067:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4068:   /*   } */
                   4069:   /*   printf("\n"); */
                   4070:   /*   fprintf(ficlog,"\n"); */
                   4071:   /* } */
                   4072: 
1.126     brouard  4073:   /* Recompute Inverse */
1.203     brouard  4074:   /* for (i=1;i<=npar;i++) */
                   4075:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4076:   /* ludcmp(a,npar,indx,&pd); */
                   4077: 
                   4078:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4079: 
                   4080:   /* for (j=1;j<=npar;j++) { */
                   4081:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4082:   /*   x[j]=1; */
                   4083:   /*   lubksb(a,npar,indx,x); */
                   4084:   /*   for (i=1;i<=npar;i++){  */
                   4085:   /*     y[i][j]=x[i]; */
                   4086:   /*     printf("%.3e ",y[i][j]); */
                   4087:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4088:   /*   } */
                   4089:   /*   printf("\n"); */
                   4090:   /*   fprintf(ficlog,"\n"); */
                   4091:   /* } */
                   4092: 
                   4093:   /* Verifying the inverse matrix */
                   4094: #ifdef DEBUGHESS
                   4095:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4096: 
1.203     brouard  4097:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4098:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4099: 
                   4100:   for (j=1;j<=npar;j++) {
                   4101:     for (i=1;i<=npar;i++){ 
1.203     brouard  4102:       printf("%.2f ",y[i][j]);
                   4103:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4104:     }
                   4105:     printf("\n");
                   4106:     fprintf(ficlog,"\n");
                   4107:   }
1.203     brouard  4108: #endif
1.126     brouard  4109: 
                   4110:   free_matrix(a,1,npar,1,npar);
                   4111:   free_matrix(y,1,npar,1,npar);
                   4112:   free_vector(x,1,npar);
                   4113:   free_ivector(indx,1,npar);
1.203     brouard  4114:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4115: 
                   4116: 
                   4117: }
                   4118: 
                   4119: /*************** hessian matrix ****************/
                   4120: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4121: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4122:   int i;
                   4123:   int l=1, lmax=20;
1.203     brouard  4124:   double k1,k2, res, fx;
1.132     brouard  4125:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4126:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4127:   int k=0,kmax=10;
                   4128:   double l1;
                   4129: 
                   4130:   fx=func(x);
                   4131:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4132:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4133:     l1=pow(10,l);
                   4134:     delts=delt;
                   4135:     for(k=1 ; k <kmax; k=k+1){
                   4136:       delt = delta*(l1*k);
                   4137:       p2[theta]=x[theta] +delt;
1.145     brouard  4138:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4139:       p2[theta]=x[theta]-delt;
                   4140:       k2=func(p2)-fx;
                   4141:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4142:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4143:       
1.203     brouard  4144: #ifdef DEBUGHESSII
1.126     brouard  4145:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4146:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4147: #endif
                   4148:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4149:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4150:        k=kmax;
                   4151:       }
                   4152:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4153:        k=kmax; l=lmax*10;
1.126     brouard  4154:       }
                   4155:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4156:        delts=delt;
                   4157:       }
1.203     brouard  4158:     } /* End loop k */
1.126     brouard  4159:   }
                   4160:   delti[theta]=delts;
                   4161:   return res; 
                   4162:   
                   4163: }
                   4164: 
1.203     brouard  4165: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4166: {
                   4167:   int i;
1.164     brouard  4168:   int l=1, lmax=20;
1.126     brouard  4169:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4170:   double p2[MAXPARM+1];
1.203     brouard  4171:   int k, kmax=1;
                   4172:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4173: 
                   4174:   int firstime=0;
1.203     brouard  4175:   
1.126     brouard  4176:   fx=func(x);
1.203     brouard  4177:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4178:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4179:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4180:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4181:     k1=func(p2)-fx;
                   4182:   
1.203     brouard  4183:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4184:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4185:     k2=func(p2)-fx;
                   4186:   
1.203     brouard  4187:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4188:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4189:     k3=func(p2)-fx;
                   4190:   
1.203     brouard  4191:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4192:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4193:     k4=func(p2)-fx;
1.203     brouard  4194:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4195:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4196:       firstime=1;
1.203     brouard  4197:       kmax=kmax+10;
1.208     brouard  4198:     }
                   4199:     if(kmax >=10 || firstime ==1){
1.246     brouard  4200:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4201:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4202:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4203:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4204:     }
                   4205: #ifdef DEBUGHESSIJ
                   4206:     v1=hess[thetai][thetai];
                   4207:     v2=hess[thetaj][thetaj];
                   4208:     cv12=res;
                   4209:     /* Computing eigen value of Hessian matrix */
                   4210:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4211:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4212:     if ((lc2 <0) || (lc1 <0) ){
                   4213:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4214:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4215:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4216:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4217:     }
1.126     brouard  4218: #endif
                   4219:   }
                   4220:   return res;
                   4221: }
                   4222: 
1.203     brouard  4223:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4224: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4225: /* { */
                   4226: /*   int i; */
                   4227: /*   int l=1, lmax=20; */
                   4228: /*   double k1,k2,k3,k4,res,fx; */
                   4229: /*   double p2[MAXPARM+1]; */
                   4230: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4231: /*   int k=0,kmax=10; */
                   4232: /*   double l1; */
                   4233:   
                   4234: /*   fx=func(x); */
                   4235: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4236: /*     l1=pow(10,l); */
                   4237: /*     delts=delt; */
                   4238: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4239: /*       delt = delti*(l1*k); */
                   4240: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4241: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4242: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4243: /*       k1=func(p2)-fx; */
                   4244:       
                   4245: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4246: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4247: /*       k2=func(p2)-fx; */
                   4248:       
                   4249: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4250: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4251: /*       k3=func(p2)-fx; */
                   4252:       
                   4253: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4254: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4255: /*       k4=func(p2)-fx; */
                   4256: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4257: /* #ifdef DEBUGHESSIJ */
                   4258: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4259: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4260: /* #endif */
                   4261: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4262: /*     k=kmax; */
                   4263: /*       } */
                   4264: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4265: /*     k=kmax; l=lmax*10; */
                   4266: /*       } */
                   4267: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4268: /*     delts=delt; */
                   4269: /*       } */
                   4270: /*     } /\* End loop k *\/ */
                   4271: /*   } */
                   4272: /*   delti[theta]=delts; */
                   4273: /*   return res;  */
                   4274: /* } */
                   4275: 
                   4276: 
1.126     brouard  4277: /************** Inverse of matrix **************/
                   4278: void ludcmp(double **a, int n, int *indx, double *d) 
                   4279: { 
                   4280:   int i,imax,j,k; 
                   4281:   double big,dum,sum,temp; 
                   4282:   double *vv; 
                   4283:  
                   4284:   vv=vector(1,n); 
                   4285:   *d=1.0; 
                   4286:   for (i=1;i<=n;i++) { 
                   4287:     big=0.0; 
                   4288:     for (j=1;j<=n;j++) 
                   4289:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4290:     if (big == 0.0){
                   4291:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4292:       for (j=1;j<=n;j++) {
                   4293:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4294:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4295:       }
                   4296:       fflush(ficlog);
                   4297:       fclose(ficlog);
                   4298:       nrerror("Singular matrix in routine ludcmp"); 
                   4299:     }
1.126     brouard  4300:     vv[i]=1.0/big; 
                   4301:   } 
                   4302:   for (j=1;j<=n;j++) { 
                   4303:     for (i=1;i<j;i++) { 
                   4304:       sum=a[i][j]; 
                   4305:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4306:       a[i][j]=sum; 
                   4307:     } 
                   4308:     big=0.0; 
                   4309:     for (i=j;i<=n;i++) { 
                   4310:       sum=a[i][j]; 
                   4311:       for (k=1;k<j;k++) 
                   4312:        sum -= a[i][k]*a[k][j]; 
                   4313:       a[i][j]=sum; 
                   4314:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4315:        big=dum; 
                   4316:        imax=i; 
                   4317:       } 
                   4318:     } 
                   4319:     if (j != imax) { 
                   4320:       for (k=1;k<=n;k++) { 
                   4321:        dum=a[imax][k]; 
                   4322:        a[imax][k]=a[j][k]; 
                   4323:        a[j][k]=dum; 
                   4324:       } 
                   4325:       *d = -(*d); 
                   4326:       vv[imax]=vv[j]; 
                   4327:     } 
                   4328:     indx[j]=imax; 
                   4329:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4330:     if (j != n) { 
                   4331:       dum=1.0/(a[j][j]); 
                   4332:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4333:     } 
                   4334:   } 
                   4335:   free_vector(vv,1,n);  /* Doesn't work */
                   4336: ;
                   4337: } 
                   4338: 
                   4339: void lubksb(double **a, int n, int *indx, double b[]) 
                   4340: { 
                   4341:   int i,ii=0,ip,j; 
                   4342:   double sum; 
                   4343:  
                   4344:   for (i=1;i<=n;i++) { 
                   4345:     ip=indx[i]; 
                   4346:     sum=b[ip]; 
                   4347:     b[ip]=b[i]; 
                   4348:     if (ii) 
                   4349:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4350:     else if (sum) ii=i; 
                   4351:     b[i]=sum; 
                   4352:   } 
                   4353:   for (i=n;i>=1;i--) { 
                   4354:     sum=b[i]; 
                   4355:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4356:     b[i]=sum/a[i][i]; 
                   4357:   } 
                   4358: } 
                   4359: 
                   4360: void pstamp(FILE *fichier)
                   4361: {
1.196     brouard  4362:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4363: }
                   4364: 
1.253     brouard  4365: 
                   4366: 
1.126     brouard  4367: /************ Frequencies ********************/
1.251     brouard  4368: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4369:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4370:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4371: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4372:   
1.265     brouard  4373:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4374:   int iind=0, iage=0;
                   4375:   int mi; /* Effective wave */
                   4376:   int first;
                   4377:   double ***freq; /* Frequencies */
1.268     brouard  4378:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4379:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4380:   double *meanq, *stdq, *idq;
1.226     brouard  4381:   double **meanqt;
                   4382:   double *pp, **prop, *posprop, *pospropt;
                   4383:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4384:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4385:   double agebegin, ageend;
                   4386:     
                   4387:   pp=vector(1,nlstate);
1.251     brouard  4388:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4389:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4390:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4391:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4392:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4393:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4394:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4395:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4396:   strcpy(fileresp,"P_");
                   4397:   strcat(fileresp,fileresu);
                   4398:   /*strcat(fileresphtm,fileresu);*/
                   4399:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4400:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4401:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4402:     exit(0);
                   4403:   }
1.240     brouard  4404:   
1.226     brouard  4405:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4406:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4407:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4408:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4409:     fflush(ficlog);
                   4410:     exit(70); 
                   4411:   }
                   4412:   else{
                   4413:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4414: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4415: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4416:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4417:   }
1.237     brouard  4418:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4419:   
1.226     brouard  4420:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4421:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4422:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4423:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4424:     fflush(ficlog);
                   4425:     exit(70); 
1.240     brouard  4426:   } else{
1.226     brouard  4427:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4428: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4429: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4430:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4431:   }
1.240     brouard  4432:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4433:   
1.253     brouard  4434:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4435:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4436:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4437:   j1=0;
1.126     brouard  4438:   
1.227     brouard  4439:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4440:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4441:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4442:   
                   4443:   
1.226     brouard  4444:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4445:      reference=low_education V1=0,V2=0
                   4446:      med_educ                V1=1 V2=0, 
                   4447:      high_educ               V1=0 V2=1
                   4448:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4449:   */
1.249     brouard  4450:   dateintsum=0;
                   4451:   k2cpt=0;
                   4452: 
1.253     brouard  4453:   if(cptcoveff == 0 )
1.265     brouard  4454:     nl=1;  /* Constant and age model only */
1.253     brouard  4455:   else
                   4456:     nl=2;
1.265     brouard  4457: 
                   4458:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4459:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4460:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4461:    *     freq[s1][s2][iage] =0.
                   4462:    *     Loop on iind
                   4463:    *       ++freq[s1][s2][iage] weighted
                   4464:    *     end iind
                   4465:    *     if covariate and j!0
                   4466:    *       headers Variable on one line
                   4467:    *     endif cov j!=0
                   4468:    *     header of frequency table by age
                   4469:    *     Loop on age
                   4470:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4471:    *       pos+=freq[s1][s2][iage] weighted
                   4472:    *       Loop on s1 initial state
                   4473:    *         fprintf(ficresp
                   4474:    *       end s1
                   4475:    *     end age
                   4476:    *     if j!=0 computes starting values
                   4477:    *     end compute starting values
                   4478:    *   end j1
                   4479:    * end nl 
                   4480:    */
1.253     brouard  4481:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4482:     if(nj==1)
                   4483:       j=0;  /* First pass for the constant */
1.265     brouard  4484:     else{
1.253     brouard  4485:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4486:     }
1.251     brouard  4487:     first=1;
1.265     brouard  4488:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4489:       posproptt=0.;
                   4490:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4491:        scanf("%d", i);*/
                   4492:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4493:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4494:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4495:            freq[i][s2][m]=0;
1.251     brouard  4496:       
                   4497:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4498:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4499:          prop[i][m]=0;
                   4500:        posprop[i]=0;
                   4501:        pospropt[i]=0;
                   4502:       }
1.283     brouard  4503:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4504:         idq[z1]=0.;
                   4505:         meanq[z1]=0.;
                   4506:         stdq[z1]=0.;
1.283     brouard  4507:       }
                   4508:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4509:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4510:       /*         meanqt[m][z1]=0.; */
                   4511:       /*       } */
                   4512:       /* }       */
1.251     brouard  4513:       /* dateintsum=0; */
                   4514:       /* k2cpt=0; */
                   4515:       
1.265     brouard  4516:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4517:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4518:        bool=1;
                   4519:        if(j !=0){
                   4520:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4521:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4522:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4523:                /* if(Tvaraff[z1] ==-20){ */
                   4524:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4525:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4526:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4527:                /* }else  */
                   4528:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4529:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4530:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4531:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4532:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4533:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4534:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4535:                } /* Onlyf fixed */
                   4536:              } /* end z1 */
                   4537:            } /* cptcovn > 0 */
                   4538:          } /* end any */
                   4539:        }/* end j==0 */
1.265     brouard  4540:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4541:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4542:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4543:            m=mw[mi][iind];
                   4544:            if(j!=0){
                   4545:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4546:                for (z1=1; z1<=cptcoveff; z1++) {
                   4547:                  if( Fixed[Tmodelind[z1]]==1){
                   4548:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4549:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4550:                                                                                      value is -1, we don't select. It differs from the 
                   4551:                                                                                      constant and age model which counts them. */
                   4552:                      bool=0; /* not selected */
                   4553:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4554:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4555:                      bool=0;
                   4556:                    }
                   4557:                  }
                   4558:                }
                   4559:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4560:            } /* end j==0 */
                   4561:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4562:            if(bool==1){ /*Selected */
1.251     brouard  4563:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4564:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4565:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4566:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4567:              if(m >=firstpass && m <=lastpass){
                   4568:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4569:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4570:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4571:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4572:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4573:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4574:                if (m<lastpass) {
                   4575:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4576:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4577:                  if(s[m][iind]==-1)
                   4578:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4579:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4580:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4581:                    idq[z1]=idq[z1]+weight[iind];
                   4582:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4583:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4584:                  }
1.251     brouard  4585:                  /* if((int)agev[m][iind] == 55) */
                   4586:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4587:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4588:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4589:                }
1.251     brouard  4590:              } /* end if between passes */  
                   4591:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4592:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4593:                k2cpt++;
                   4594:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4595:              }
1.251     brouard  4596:            }else{
                   4597:              bool=1;
                   4598:            }/* end bool 2 */
                   4599:          } /* end m */
1.284     brouard  4600:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4601:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4602:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4603:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4604:          /* } */
1.251     brouard  4605:        } /* end bool */
                   4606:       } /* end iind = 1 to imx */
                   4607:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4608:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4609:       
                   4610:       
                   4611:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4612:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4613:         pstamp(ficresp);
1.251     brouard  4614:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4615:         pstamp(ficresp);
1.251     brouard  4616:        printf( "\n#********** Variable "); 
                   4617:        fprintf(ficresp, "\n#********** Variable "); 
                   4618:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4619:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4620:        fprintf(ficlog, "\n#********** Variable "); 
                   4621:        for (z1=1; z1<=cptcoveff; z1++){
                   4622:          if(!FixedV[Tvaraff[z1]]){
                   4623:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4624:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4625:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4626:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4627:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4628:          }else{
1.251     brouard  4629:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4630:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4631:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4632:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4633:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4634:          }
                   4635:        }
                   4636:        printf( "**********\n#");
                   4637:        fprintf(ficresp, "**********\n#");
                   4638:        fprintf(ficresphtm, "**********</h3>\n");
                   4639:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4640:        fprintf(ficlog, "**********\n");
                   4641:       }
1.284     brouard  4642:       /*
                   4643:        Printing means of quantitative variables if any
                   4644:       */
                   4645:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4646:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4647:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4648:        if(weightopt==1){
                   4649:          printf(" Weighted mean and standard deviation of");
                   4650:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4651:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4652:        }
1.285     brouard  4653:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4654:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4655:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4656:       }
                   4657:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4658:       /*       for(m=1;m<=lastpass;m++){ */
                   4659:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4660:       /*   } */
                   4661:       /* } */
1.283     brouard  4662: 
1.251     brouard  4663:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4664:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4665:         fprintf(ficresp, " Age");
                   4666:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4667:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4668:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4669:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4670:       }
1.265     brouard  4671:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4672:       fprintf(ficresphtm, "\n");
                   4673:       
                   4674:       /* Header of frequency table by age */
                   4675:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4676:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4677:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4678:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4679:          if(s2!=0 && m!=0)
                   4680:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4681:        }
1.226     brouard  4682:       }
1.251     brouard  4683:       fprintf(ficresphtmfr, "\n");
                   4684:     
                   4685:       /* For each age */
                   4686:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4687:        fprintf(ficresphtm,"<tr>");
                   4688:        if(iage==iagemax+1){
                   4689:          fprintf(ficlog,"1");
                   4690:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4691:        }else if(iage==iagemax+2){
                   4692:          fprintf(ficlog,"0");
                   4693:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4694:        }else if(iage==iagemax+3){
                   4695:          fprintf(ficlog,"Total");
                   4696:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4697:        }else{
1.240     brouard  4698:          if(first==1){
1.251     brouard  4699:            first=0;
                   4700:            printf("See log file for details...\n");
                   4701:          }
                   4702:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4703:          fprintf(ficlog,"Age %d", iage);
                   4704:        }
1.265     brouard  4705:        for(s1=1; s1 <=nlstate ; s1++){
                   4706:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4707:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4708:        }
1.265     brouard  4709:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4710:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4711:            pos += freq[s1][m][iage];
                   4712:          if(pp[s1]>=1.e-10){
1.251     brouard  4713:            if(first==1){
1.265     brouard  4714:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4715:            }
1.265     brouard  4716:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4717:          }else{
                   4718:            if(first==1)
1.265     brouard  4719:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4720:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4721:          }
                   4722:        }
                   4723:       
1.265     brouard  4724:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4725:          /* posprop[s1]=0; */
                   4726:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4727:            pp[s1] += freq[s1][m][iage];
                   4728:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4729:       
                   4730:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4731:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4732:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4733:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4734:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4735:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4736:        }
                   4737:        
                   4738:        /* Writing ficresp */
                   4739:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4740:           if( iage <= iagemax){
                   4741:            fprintf(ficresp," %d",iage);
                   4742:           }
                   4743:         }else if( nj==2){
                   4744:           if( iage <= iagemax){
                   4745:            fprintf(ficresp," %d",iage);
                   4746:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4747:           }
1.240     brouard  4748:        }
1.265     brouard  4749:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4750:          if(pos>=1.e-5){
1.251     brouard  4751:            if(first==1)
1.265     brouard  4752:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4753:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4754:          }else{
                   4755:            if(first==1)
1.265     brouard  4756:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4757:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4758:          }
                   4759:          if( iage <= iagemax){
                   4760:            if(pos>=1.e-5){
1.265     brouard  4761:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4762:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4763:               }else if( nj==2){
                   4764:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4765:               }
                   4766:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4767:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4768:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4769:            } else{
                   4770:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4771:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4772:            }
1.240     brouard  4773:          }
1.265     brouard  4774:          pospropt[s1] +=posprop[s1];
                   4775:        } /* end loop s1 */
1.251     brouard  4776:        /* pospropt=0.; */
1.265     brouard  4777:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4778:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4779:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4780:              if(first==1){
1.265     brouard  4781:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4782:              }
1.265     brouard  4783:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4784:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4785:            }
1.265     brouard  4786:            if(s1!=0 && m!=0)
                   4787:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4788:          }
1.265     brouard  4789:        } /* end loop s1 */
1.251     brouard  4790:        posproptt=0.; 
1.265     brouard  4791:        for(s1=1; s1 <=nlstate; s1++){
                   4792:          posproptt += pospropt[s1];
1.251     brouard  4793:        }
                   4794:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4795:        fprintf(ficresphtm,"</tr>\n");
                   4796:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4797:          if(iage <= iagemax)
                   4798:            fprintf(ficresp,"\n");
1.240     brouard  4799:        }
1.251     brouard  4800:        if(first==1)
                   4801:          printf("Others in log...\n");
                   4802:        fprintf(ficlog,"\n");
                   4803:       } /* end loop age iage */
1.265     brouard  4804:       
1.251     brouard  4805:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4806:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4807:        if(posproptt < 1.e-5){
1.265     brouard  4808:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4809:        }else{
1.265     brouard  4810:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4811:        }
1.226     brouard  4812:       }
1.251     brouard  4813:       fprintf(ficresphtm,"</tr>\n");
                   4814:       fprintf(ficresphtm,"</table>\n");
                   4815:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4816:       if(posproptt < 1.e-5){
1.251     brouard  4817:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4818:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4819:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4820:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4821:        invalidvarcomb[j1]=1;
1.226     brouard  4822:       }else{
1.251     brouard  4823:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4824:        invalidvarcomb[j1]=0;
1.226     brouard  4825:       }
1.251     brouard  4826:       fprintf(ficresphtmfr,"</table>\n");
                   4827:       fprintf(ficlog,"\n");
                   4828:       if(j!=0){
                   4829:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4830:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4831:          for(k=1; k <=(nlstate+ndeath); k++){
                   4832:            if (k != i) {
1.265     brouard  4833:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4834:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4835:                  if(j1==1){ /* All dummy covariates to zero */
                   4836:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4837:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4838:                    printf("%d%d ",i,k);
                   4839:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4840:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4841:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4842:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4843:                  }
1.253     brouard  4844:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4845:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4846:                    x[iage]= (double)iage;
                   4847:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4848:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4849:                  }
1.268     brouard  4850:                  /* Some are not finite, but linreg will ignore these ages */
                   4851:                  no=0;
1.253     brouard  4852:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4853:                  pstart[s1]=b;
                   4854:                  pstart[s1-1]=a;
1.252     brouard  4855:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4856:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4857:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4858:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4859:                  printf("%d%d ",i,k);
                   4860:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4861:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4862:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4863:                  ;
                   4864:                }
                   4865:                /* printf("%12.7f )", param[i][jj][k]); */
                   4866:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4867:                s1++; 
1.251     brouard  4868:              } /* end jj */
                   4869:            } /* end k!= i */
                   4870:          } /* end k */
1.265     brouard  4871:        } /* end i, s1 */
1.251     brouard  4872:       } /* end j !=0 */
                   4873:     } /* end selected combination of covariate j1 */
                   4874:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4875:       printf("#Freqsummary: Starting values for the constants:\n");
                   4876:       fprintf(ficlog,"\n");
1.265     brouard  4877:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4878:        for(k=1; k <=(nlstate+ndeath); k++){
                   4879:          if (k != i) {
                   4880:            printf("%d%d ",i,k);
                   4881:            fprintf(ficlog,"%d%d ",i,k);
                   4882:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4883:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4884:              if(jj==1){ /* Age has to be done */
1.265     brouard  4885:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4886:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4887:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4888:              }
                   4889:              /* printf("%12.7f )", param[i][jj][k]); */
                   4890:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4891:              s1++; 
1.250     brouard  4892:            }
1.251     brouard  4893:            printf("\n");
                   4894:            fprintf(ficlog,"\n");
1.250     brouard  4895:          }
                   4896:        }
1.284     brouard  4897:       } /* end of state i */
1.251     brouard  4898:       printf("#Freqsummary\n");
                   4899:       fprintf(ficlog,"\n");
1.265     brouard  4900:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4901:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4902:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4903:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4904:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4905:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4906:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4907:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4908:          /* } */
                   4909:        }
1.265     brouard  4910:       } /* end loop s1 */
1.251     brouard  4911:       
                   4912:       printf("\n");
                   4913:       fprintf(ficlog,"\n");
                   4914:     } /* end j=0 */
1.249     brouard  4915:   } /* end j */
1.252     brouard  4916: 
1.253     brouard  4917:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4918:     for(i=1, jk=1; i <=nlstate; i++){
                   4919:       for(j=1; j <=nlstate+ndeath; j++){
                   4920:        if(j!=i){
                   4921:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4922:          printf("%1d%1d",i,j);
                   4923:          fprintf(ficparo,"%1d%1d",i,j);
                   4924:          for(k=1; k<=ncovmodel;k++){
                   4925:            /*    printf(" %lf",param[i][j][k]); */
                   4926:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4927:            p[jk]=pstart[jk];
                   4928:            printf(" %f ",pstart[jk]);
                   4929:            fprintf(ficparo," %f ",pstart[jk]);
                   4930:            jk++;
                   4931:          }
                   4932:          printf("\n");
                   4933:          fprintf(ficparo,"\n");
                   4934:        }
                   4935:       }
                   4936:     }
                   4937:   } /* end mle=-2 */
1.226     brouard  4938:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4939:   
1.226     brouard  4940:   fclose(ficresp);
                   4941:   fclose(ficresphtm);
                   4942:   fclose(ficresphtmfr);
1.283     brouard  4943:   free_vector(idq,1,nqfveff);
1.226     brouard  4944:   free_vector(meanq,1,nqfveff);
1.284     brouard  4945:   free_vector(stdq,1,nqfveff);
1.226     brouard  4946:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4947:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4948:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4949:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4950:   free_vector(pospropt,1,nlstate);
                   4951:   free_vector(posprop,1,nlstate);
1.251     brouard  4952:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4953:   free_vector(pp,1,nlstate);
                   4954:   /* End of freqsummary */
                   4955: }
1.126     brouard  4956: 
1.268     brouard  4957: /* Simple linear regression */
                   4958: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4959: 
                   4960:   /* y=a+bx regression */
                   4961:   double   sumx = 0.0;                        /* sum of x                      */
                   4962:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4963:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4964:   double   sumy = 0.0;                        /* sum of y                      */
                   4965:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4966:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4967:   double yhat;
                   4968:   
                   4969:   double denom=0;
                   4970:   int i;
                   4971:   int ne=*no;
                   4972:   
                   4973:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4974:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4975:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4976:       continue;
                   4977:     }
                   4978:     ne=ne+1;
                   4979:     sumx  += x[i];       
                   4980:     sumx2 += x[i]*x[i];  
                   4981:     sumxy += x[i] * y[i];
                   4982:     sumy  += y[i];      
                   4983:     sumy2 += y[i]*y[i]; 
                   4984:     denom = (ne * sumx2 - sumx*sumx);
                   4985:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4986:   } 
                   4987:   
                   4988:   denom = (ne * sumx2 - sumx*sumx);
                   4989:   if (denom == 0) {
                   4990:     // vertical, slope m is infinity
                   4991:     *b = INFINITY;
                   4992:     *a = 0;
                   4993:     if (r) *r = 0;
                   4994:     return 1;
                   4995:   }
                   4996:   
                   4997:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   4998:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   4999:   if (r!=NULL) {
                   5000:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5001:       sqrt((sumx2 - sumx*sumx/ne) *
                   5002:           (sumy2 - sumy*sumy/ne));
                   5003:   }
                   5004:   *no=ne;
                   5005:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5006:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5007:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5008:       continue;
                   5009:     }
                   5010:     ne=ne+1;
                   5011:     yhat = y[i] - *a -*b* x[i];
                   5012:     sume2  += yhat * yhat ;       
                   5013:     
                   5014:     denom = (ne * sumx2 - sumx*sumx);
                   5015:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5016:   } 
                   5017:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5018:   *sa= *sb * sqrt(sumx2/ne);
                   5019:   
                   5020:   return 0; 
                   5021: }
                   5022: 
1.126     brouard  5023: /************ Prevalence ********************/
1.227     brouard  5024: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5025: {  
                   5026:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5027:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5028:      We still use firstpass and lastpass as another selection.
                   5029:   */
1.126     brouard  5030:  
1.227     brouard  5031:   int i, m, jk, j1, bool, z1,j, iv;
                   5032:   int mi; /* Effective wave */
                   5033:   int iage;
                   5034:   double agebegin, ageend;
                   5035: 
                   5036:   double **prop;
                   5037:   double posprop; 
                   5038:   double  y2; /* in fractional years */
                   5039:   int iagemin, iagemax;
                   5040:   int first; /** to stop verbosity which is redirected to log file */
                   5041: 
                   5042:   iagemin= (int) agemin;
                   5043:   iagemax= (int) agemax;
                   5044:   /*pp=vector(1,nlstate);*/
1.251     brouard  5045:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5046:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5047:   j1=0;
1.222     brouard  5048:   
1.227     brouard  5049:   /*j=cptcoveff;*/
                   5050:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5051:   
1.227     brouard  5052:   first=1;
                   5053:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5054:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5055:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5056:        prop[i][iage]=0.0;
                   5057:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5058:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5059:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5060:     
                   5061:     for (i=1; i<=imx; i++) { /* Each individual */
                   5062:       bool=1;
                   5063:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5064:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5065:        m=mw[mi][i];
                   5066:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5067:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5068:        for (z1=1; z1<=cptcoveff; z1++){
                   5069:          if( Fixed[Tmodelind[z1]]==1){
                   5070:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5071:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5072:              bool=0;
                   5073:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5074:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5075:              bool=0;
                   5076:            }
                   5077:        }
                   5078:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5079:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5080:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5081:          if(m >=firstpass && m <=lastpass){
                   5082:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5083:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5084:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5085:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5086:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5087:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5088:                exit(1);
                   5089:              }
                   5090:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5091:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5092:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5093:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5094:              } /* end valid statuses */ 
                   5095:            } /* end selection of dates */
                   5096:          } /* end selection of waves */
                   5097:        } /* end bool */
                   5098:       } /* end wave */
                   5099:     } /* end individual */
                   5100:     for(i=iagemin; i <= iagemax+3; i++){  
                   5101:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5102:        posprop += prop[jk][i]; 
                   5103:       } 
                   5104:       
                   5105:       for(jk=1; jk <=nlstate ; jk++){      
                   5106:        if( i <=  iagemax){ 
                   5107:          if(posprop>=1.e-5){ 
                   5108:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5109:          } else{
                   5110:            if(first==1){
                   5111:              first=0;
1.266     brouard  5112:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5113:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5114:            }else{
                   5115:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5116:            }
                   5117:          }
                   5118:        } 
                   5119:       }/* end jk */ 
                   5120:     }/* end i */ 
1.222     brouard  5121:      /*} *//* end i1 */
1.227     brouard  5122:   } /* end j1 */
1.222     brouard  5123:   
1.227     brouard  5124:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5125:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5126:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5127: }  /* End of prevalence */
1.126     brouard  5128: 
                   5129: /************* Waves Concatenation ***************/
                   5130: 
                   5131: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5132: {
                   5133:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5134:      Death is a valid wave (if date is known).
                   5135:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5136:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5137:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5138:   */
1.126     brouard  5139: 
1.224     brouard  5140:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5141:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5142:      double sum=0., jmean=0.;*/
1.224     brouard  5143:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5144:   int j, k=0,jk, ju, jl;
                   5145:   double sum=0.;
                   5146:   first=0;
1.214     brouard  5147:   firstwo=0;
1.217     brouard  5148:   firsthree=0;
1.218     brouard  5149:   firstfour=0;
1.164     brouard  5150:   jmin=100000;
1.126     brouard  5151:   jmax=-1;
                   5152:   jmean=0.;
1.224     brouard  5153: 
                   5154: /* Treating live states */
1.214     brouard  5155:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5156:     mi=0;  /* First valid wave */
1.227     brouard  5157:     mli=0; /* Last valid wave */
1.126     brouard  5158:     m=firstpass;
1.214     brouard  5159:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5160:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5161:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5162:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5163:        mw[++mi][i]=m;
                   5164:        mli=m;
1.224     brouard  5165:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5166:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5167:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5168:       }
1.227     brouard  5169:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5170: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5171:        break;
1.224     brouard  5172: #else
1.227     brouard  5173:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5174:          if(firsthree == 0){
1.262     brouard  5175:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5176:            firsthree=1;
                   5177:          }
1.262     brouard  5178:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5179:          mw[++mi][i]=m;
                   5180:          mli=m;
                   5181:        }
                   5182:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5183:          nbwarn++;
                   5184:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5185:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5186:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5187:          }
                   5188:          break;
                   5189:        }
                   5190:        break;
1.224     brouard  5191: #endif
1.227     brouard  5192:       }/* End m >= lastpass */
1.126     brouard  5193:     }/* end while */
1.224     brouard  5194: 
1.227     brouard  5195:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5196:     /* After last pass */
1.224     brouard  5197: /* Treating death states */
1.214     brouard  5198:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5199:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5200:       /* } */
1.126     brouard  5201:       mi++;    /* Death is another wave */
                   5202:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5203:       /* Only death is a correct wave */
1.126     brouard  5204:       mw[mi][i]=m;
1.257     brouard  5205:     } /* else not in a death state */
1.224     brouard  5206: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5207:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5208:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5209:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5210:          nbwarn++;
                   5211:          if(firstfiv==0){
                   5212:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5213:            firstfiv=1;
                   5214:          }else{
                   5215:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5216:          }
                   5217:        }else{ /* Death occured afer last wave potential bias */
                   5218:          nberr++;
                   5219:          if(firstwo==0){
1.257     brouard  5220:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5221:            firstwo=1;
                   5222:          }
1.257     brouard  5223:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5224:        }
1.257     brouard  5225:       }else{ /* if date of interview is unknown */
1.227     brouard  5226:        /* death is known but not confirmed by death status at any wave */
                   5227:        if(firstfour==0){
                   5228:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5229:          firstfour=1;
                   5230:        }
                   5231:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5232:       }
1.224     brouard  5233:     } /* end if date of death is known */
                   5234: #endif
                   5235:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5236:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5237:     if(mi==0){
                   5238:       nbwarn++;
                   5239:       if(first==0){
1.227     brouard  5240:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5241:        first=1;
1.126     brouard  5242:       }
                   5243:       if(first==1){
1.227     brouard  5244:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5245:       }
                   5246:     } /* end mi==0 */
                   5247:   } /* End individuals */
1.214     brouard  5248:   /* wav and mw are no more changed */
1.223     brouard  5249:        
1.214     brouard  5250:   
1.126     brouard  5251:   for(i=1; i<=imx; i++){
                   5252:     for(mi=1; mi<wav[i];mi++){
                   5253:       if (stepm <=0)
1.227     brouard  5254:        dh[mi][i]=1;
1.126     brouard  5255:       else{
1.260     brouard  5256:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5257:          if (agedc[i] < 2*AGESUP) {
                   5258:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5259:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5260:            else if(j<0){
                   5261:              nberr++;
                   5262:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5263:              j=1; /* Temporary Dangerous patch */
                   5264:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5265:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5266:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5267:            }
                   5268:            k=k+1;
                   5269:            if (j >= jmax){
                   5270:              jmax=j;
                   5271:              ijmax=i;
                   5272:            }
                   5273:            if (j <= jmin){
                   5274:              jmin=j;
                   5275:              ijmin=i;
                   5276:            }
                   5277:            sum=sum+j;
                   5278:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5279:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5280:          }
                   5281:        }
                   5282:        else{
                   5283:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5284: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5285:                                        
1.227     brouard  5286:          k=k+1;
                   5287:          if (j >= jmax) {
                   5288:            jmax=j;
                   5289:            ijmax=i;
                   5290:          }
                   5291:          else if (j <= jmin){
                   5292:            jmin=j;
                   5293:            ijmin=i;
                   5294:          }
                   5295:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5296:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5297:          if(j<0){
                   5298:            nberr++;
                   5299:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5300:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5301:          }
                   5302:          sum=sum+j;
                   5303:        }
                   5304:        jk= j/stepm;
                   5305:        jl= j -jk*stepm;
                   5306:        ju= j -(jk+1)*stepm;
                   5307:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5308:          if(jl==0){
                   5309:            dh[mi][i]=jk;
                   5310:            bh[mi][i]=0;
                   5311:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5312:                  * to avoid the price of an extra matrix product in likelihood */
                   5313:            dh[mi][i]=jk+1;
                   5314:            bh[mi][i]=ju;
                   5315:          }
                   5316:        }else{
                   5317:          if(jl <= -ju){
                   5318:            dh[mi][i]=jk;
                   5319:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5320:                                 * is higher than the multiple of stepm and negative otherwise.
                   5321:                                 */
                   5322:          }
                   5323:          else{
                   5324:            dh[mi][i]=jk+1;
                   5325:            bh[mi][i]=ju;
                   5326:          }
                   5327:          if(dh[mi][i]==0){
                   5328:            dh[mi][i]=1; /* At least one step */
                   5329:            bh[mi][i]=ju; /* At least one step */
                   5330:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5331:          }
                   5332:        } /* end if mle */
1.126     brouard  5333:       }
                   5334:     } /* end wave */
                   5335:   }
                   5336:   jmean=sum/k;
                   5337:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5338:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5339: }
1.126     brouard  5340: 
                   5341: /*********** Tricode ****************************/
1.220     brouard  5342:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5343:  {
                   5344:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5345:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5346:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5347:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5348:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5349:     */
1.130     brouard  5350: 
1.242     brouard  5351:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5352:    int modmaxcovj=0; /* Modality max of covariates j */
                   5353:    int cptcode=0; /* Modality max of covariates j */
                   5354:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5355: 
                   5356: 
1.242     brouard  5357:    /* cptcoveff=0;  */
                   5358:    /* *cptcov=0; */
1.126     brouard  5359:  
1.242     brouard  5360:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5361:    for (k=1; k <= maxncov; k++)
                   5362:      for(j=1; j<=2; j++)
                   5363:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5364: 
1.242     brouard  5365:    /* Loop on covariates without age and products and no quantitative variable */
                   5366:    /* for (j=1; j<=(cptcovs); j++) { /\* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only *\/ */
                   5367:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5368:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5369:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5370:        switch(Fixed[k]) {
                   5371:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5372:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5373:           ij=(int)(covar[Tvar[k]][i]);
                   5374:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5375:            * If product of Vn*Vm, still boolean *:
                   5376:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5377:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5378:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5379:              modality of the nth covariate of individual i. */
                   5380:           if (ij > modmaxcovj)
                   5381:             modmaxcovj=ij; 
                   5382:           else if (ij < modmincovj) 
                   5383:             modmincovj=ij; 
                   5384:           if ((ij < -1) && (ij > NCOVMAX)){
                   5385:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5386:             exit(1);
                   5387:           }else
                   5388:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5389:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5390:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5391:           /* getting the maximum value of the modality of the covariate
                   5392:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5393:              female ies 1, then modmaxcovj=1.
                   5394:           */
                   5395:         } /* end for loop on individuals i */
                   5396:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5397:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5398:         cptcode=modmaxcovj;
                   5399:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5400:         /*for (i=0; i<=cptcode; i++) {*/
                   5401:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5402:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5403:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5404:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5405:             if( j != -1){
                   5406:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5407:                                  covariate for which somebody answered excluding 
                   5408:                                  undefined. Usually 2: 0 and 1. */
                   5409:             }
                   5410:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5411:                                     covariate for which somebody answered including 
                   5412:                                     undefined. Usually 3: -1, 0 and 1. */
                   5413:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5414:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5415:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5416:                        
1.242     brouard  5417:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5418:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5419:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5420:         /* modmincovj=3; modmaxcovj = 7; */
                   5421:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5422:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5423:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5424:         /* nbcode[Tvar[j]][ij]=k; */
                   5425:         /* nbcode[Tvar[j]][1]=0; */
                   5426:         /* nbcode[Tvar[j]][2]=1; */
                   5427:         /* nbcode[Tvar[j]][3]=2; */
                   5428:         /* To be continued (not working yet). */
                   5429:         ij=0; /* ij is similar to i but can jump over null modalities */
                   5430:         for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5431:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5432:             break;
                   5433:           }
                   5434:           ij++;
                   5435:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1*/
                   5436:           cptcode = ij; /* New max modality for covar j */
                   5437:         } /* end of loop on modality i=-1 to 1 or more */
                   5438:         break;
                   5439:        case 1: /* Testing on varying covariate, could be simple and
                   5440:                * should look at waves or product of fixed *
                   5441:                * varying. No time to test -1, assuming 0 and 1 only */
                   5442:         ij=0;
                   5443:         for(i=0; i<=1;i++){
                   5444:           nbcode[Tvar[k]][++ij]=i;
                   5445:         }
                   5446:         break;
                   5447:        default:
                   5448:         break;
                   5449:        } /* end switch */
                   5450:      } /* end dummy test */
                   5451:     
                   5452:      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
                   5453:      /*        /\*recode from 0 *\/ */
                   5454:      /*                                     k is a modality. If we have model=V1+V1*sex  */
                   5455:      /*                                     then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
                   5456:      /*                                  But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
                   5457:      /*        } */
                   5458:      /*        /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
                   5459:      /*        if (ij > ncodemax[j]) { */
                   5460:      /*          printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
                   5461:      /*          fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
                   5462:      /*          break; */
                   5463:      /*        } */
                   5464:      /*   }  /\* end of loop on modality k *\/ */
                   5465:    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
                   5466:   
                   5467:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5468:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5469:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5470:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5471:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5472:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5473:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5474:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5475:   
                   5476:    ij=0;
                   5477:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5478:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5479:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5480:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5481:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5482:        /* If product not in single variable we don't print results */
                   5483:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5484:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5485:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5486:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5487:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5488:        if(Fixed[k]!=0)
                   5489:         anyvaryingduminmodel=1;
                   5490:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5491:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5492:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5493:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5494:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5495:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5496:      } 
                   5497:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5498:    /* ij--; */
                   5499:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5500:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5501:                * because they can be excluded from the model and real
                   5502:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5503:    for(j=ij+1; j<= cptcovt; j++){
                   5504:      Tvaraff[j]=0;
                   5505:      Tmodelind[j]=0;
                   5506:    }
                   5507:    for(j=ntveff+1; j<= cptcovt; j++){
                   5508:      TmodelInvind[j]=0;
                   5509:    }
                   5510:    /* To be sorted */
                   5511:    ;
                   5512:  }
1.126     brouard  5513: 
1.145     brouard  5514: 
1.126     brouard  5515: /*********** Health Expectancies ****************/
                   5516: 
1.235     brouard  5517:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5518: 
                   5519: {
                   5520:   /* Health expectancies, no variances */
1.164     brouard  5521:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5522:   int nhstepma, nstepma; /* Decreasing with age */
                   5523:   double age, agelim, hf;
                   5524:   double ***p3mat;
                   5525:   double eip;
                   5526: 
1.238     brouard  5527:   /* pstamp(ficreseij); */
1.126     brouard  5528:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5529:   fprintf(ficreseij,"# Age");
                   5530:   for(i=1; i<=nlstate;i++){
                   5531:     for(j=1; j<=nlstate;j++){
                   5532:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5533:     }
                   5534:     fprintf(ficreseij," e%1d. ",i);
                   5535:   }
                   5536:   fprintf(ficreseij,"\n");
                   5537: 
                   5538:   
                   5539:   if(estepm < stepm){
                   5540:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5541:   }
                   5542:   else  hstepm=estepm;   
                   5543:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5544:    * This is mainly to measure the difference between two models: for example
                   5545:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5546:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5547:    * progression in between and thus overestimating or underestimating according
                   5548:    * to the curvature of the survival function. If, for the same date, we 
                   5549:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5550:    * to compare the new estimate of Life expectancy with the same linear 
                   5551:    * hypothesis. A more precise result, taking into account a more precise
                   5552:    * curvature will be obtained if estepm is as small as stepm. */
                   5553: 
                   5554:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5555:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5556:      nhstepm is the number of hstepm from age to agelim 
                   5557:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5558:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5559:      and note for a fixed period like estepm months */
                   5560:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5561:      survival function given by stepm (the optimization length). Unfortunately it
                   5562:      means that if the survival funtion is printed only each two years of age and if
                   5563:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5564:      results. So we changed our mind and took the option of the best precision.
                   5565:   */
                   5566:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5567: 
                   5568:   agelim=AGESUP;
                   5569:   /* If stepm=6 months */
                   5570:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5571:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5572:     
                   5573: /* nhstepm age range expressed in number of stepm */
                   5574:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5575:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5576:   /* if (stepm >= YEARM) hstepm=1;*/
                   5577:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5578:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5579: 
                   5580:   for (age=bage; age<=fage; age ++){ 
                   5581:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5582:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5583:     /* if (stepm >= YEARM) hstepm=1;*/
                   5584:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5585: 
                   5586:     /* If stepm=6 months */
                   5587:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5588:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5589:     
1.235     brouard  5590:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5591:     
                   5592:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5593:     
                   5594:     printf("%d|",(int)age);fflush(stdout);
                   5595:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5596:     
                   5597:     /* Computing expectancies */
                   5598:     for(i=1; i<=nlstate;i++)
                   5599:       for(j=1; j<=nlstate;j++)
                   5600:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5601:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5602:          
                   5603:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5604: 
                   5605:        }
                   5606: 
                   5607:     fprintf(ficreseij,"%3.0f",age );
                   5608:     for(i=1; i<=nlstate;i++){
                   5609:       eip=0;
                   5610:       for(j=1; j<=nlstate;j++){
                   5611:        eip +=eij[i][j][(int)age];
                   5612:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5613:       }
                   5614:       fprintf(ficreseij,"%9.4f", eip );
                   5615:     }
                   5616:     fprintf(ficreseij,"\n");
                   5617:     
                   5618:   }
                   5619:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5620:   printf("\n");
                   5621:   fprintf(ficlog,"\n");
                   5622:   
                   5623: }
                   5624: 
1.235     brouard  5625:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5626: 
                   5627: {
                   5628:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5629:      to initial status i, ei. .
1.126     brouard  5630:   */
                   5631:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5632:   int nhstepma, nstepma; /* Decreasing with age */
                   5633:   double age, agelim, hf;
                   5634:   double ***p3matp, ***p3matm, ***varhe;
                   5635:   double **dnewm,**doldm;
                   5636:   double *xp, *xm;
                   5637:   double **gp, **gm;
                   5638:   double ***gradg, ***trgradg;
                   5639:   int theta;
                   5640: 
                   5641:   double eip, vip;
                   5642: 
                   5643:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5644:   xp=vector(1,npar);
                   5645:   xm=vector(1,npar);
                   5646:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5647:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5648:   
                   5649:   pstamp(ficresstdeij);
                   5650:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5651:   fprintf(ficresstdeij,"# Age");
                   5652:   for(i=1; i<=nlstate;i++){
                   5653:     for(j=1; j<=nlstate;j++)
                   5654:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5655:     fprintf(ficresstdeij," e%1d. ",i);
                   5656:   }
                   5657:   fprintf(ficresstdeij,"\n");
                   5658: 
                   5659:   pstamp(ficrescveij);
                   5660:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5661:   fprintf(ficrescveij,"# Age");
                   5662:   for(i=1; i<=nlstate;i++)
                   5663:     for(j=1; j<=nlstate;j++){
                   5664:       cptj= (j-1)*nlstate+i;
                   5665:       for(i2=1; i2<=nlstate;i2++)
                   5666:        for(j2=1; j2<=nlstate;j2++){
                   5667:          cptj2= (j2-1)*nlstate+i2;
                   5668:          if(cptj2 <= cptj)
                   5669:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5670:        }
                   5671:     }
                   5672:   fprintf(ficrescveij,"\n");
                   5673:   
                   5674:   if(estepm < stepm){
                   5675:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5676:   }
                   5677:   else  hstepm=estepm;   
                   5678:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5679:    * This is mainly to measure the difference between two models: for example
                   5680:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5681:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5682:    * progression in between and thus overestimating or underestimating according
                   5683:    * to the curvature of the survival function. If, for the same date, we 
                   5684:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5685:    * to compare the new estimate of Life expectancy with the same linear 
                   5686:    * hypothesis. A more precise result, taking into account a more precise
                   5687:    * curvature will be obtained if estepm is as small as stepm. */
                   5688: 
                   5689:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5690:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5691:      nhstepm is the number of hstepm from age to agelim 
                   5692:      nstepm is the number of stepm from age to agelin. 
                   5693:      Look at hpijx to understand the reason of that which relies in memory size
                   5694:      and note for a fixed period like estepm months */
                   5695:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5696:      survival function given by stepm (the optimization length). Unfortunately it
                   5697:      means that if the survival funtion is printed only each two years of age and if
                   5698:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5699:      results. So we changed our mind and took the option of the best precision.
                   5700:   */
                   5701:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5702: 
                   5703:   /* If stepm=6 months */
                   5704:   /* nhstepm age range expressed in number of stepm */
                   5705:   agelim=AGESUP;
                   5706:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5707:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5708:   /* if (stepm >= YEARM) hstepm=1;*/
                   5709:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5710:   
                   5711:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5712:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5713:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5714:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5715:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5716:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5717: 
                   5718:   for (age=bage; age<=fage; age ++){ 
                   5719:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5720:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5721:     /* if (stepm >= YEARM) hstepm=1;*/
                   5722:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5723:                
1.126     brouard  5724:     /* If stepm=6 months */
                   5725:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5726:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5727:     
                   5728:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5729:                
1.126     brouard  5730:     /* Computing  Variances of health expectancies */
                   5731:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5732:        decrease memory allocation */
                   5733:     for(theta=1; theta <=npar; theta++){
                   5734:       for(i=1; i<=npar; i++){ 
1.222     brouard  5735:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5736:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5737:       }
1.235     brouard  5738:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5739:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5740:                        
1.126     brouard  5741:       for(j=1; j<= nlstate; j++){
1.222     brouard  5742:        for(i=1; i<=nlstate; i++){
                   5743:          for(h=0; h<=nhstepm-1; h++){
                   5744:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5745:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5746:          }
                   5747:        }
1.126     brouard  5748:       }
1.218     brouard  5749:                        
1.126     brouard  5750:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5751:        for(h=0; h<=nhstepm-1; h++){
                   5752:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5753:        }
1.126     brouard  5754:     }/* End theta */
                   5755:     
                   5756:     
                   5757:     for(h=0; h<=nhstepm-1; h++)
                   5758:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5759:        for(theta=1; theta <=npar; theta++)
                   5760:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5761:     
1.218     brouard  5762:                
1.222     brouard  5763:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5764:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5765:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5766:                
1.222     brouard  5767:     printf("%d|",(int)age);fflush(stdout);
                   5768:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5769:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5770:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5771:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5772:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5773:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5774:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5775:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5776:       }
                   5777:     }
1.218     brouard  5778:                
1.126     brouard  5779:     /* Computing expectancies */
1.235     brouard  5780:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5781:     for(i=1; i<=nlstate;i++)
                   5782:       for(j=1; j<=nlstate;j++)
1.222     brouard  5783:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5784:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5785:                                        
1.222     brouard  5786:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5787:                                        
1.222     brouard  5788:        }
1.269     brouard  5789: 
                   5790:     /* Standard deviation of expectancies ij */                
1.126     brouard  5791:     fprintf(ficresstdeij,"%3.0f",age );
                   5792:     for(i=1; i<=nlstate;i++){
                   5793:       eip=0.;
                   5794:       vip=0.;
                   5795:       for(j=1; j<=nlstate;j++){
1.222     brouard  5796:        eip += eij[i][j][(int)age];
                   5797:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5798:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5799:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5800:       }
                   5801:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5802:     }
                   5803:     fprintf(ficresstdeij,"\n");
1.218     brouard  5804:                
1.269     brouard  5805:     /* Variance of expectancies ij */          
1.126     brouard  5806:     fprintf(ficrescveij,"%3.0f",age );
                   5807:     for(i=1; i<=nlstate;i++)
                   5808:       for(j=1; j<=nlstate;j++){
1.222     brouard  5809:        cptj= (j-1)*nlstate+i;
                   5810:        for(i2=1; i2<=nlstate;i2++)
                   5811:          for(j2=1; j2<=nlstate;j2++){
                   5812:            cptj2= (j2-1)*nlstate+i2;
                   5813:            if(cptj2 <= cptj)
                   5814:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5815:          }
1.126     brouard  5816:       }
                   5817:     fprintf(ficrescveij,"\n");
1.218     brouard  5818:                
1.126     brouard  5819:   }
                   5820:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5821:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5822:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5823:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5824:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5825:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5826:   printf("\n");
                   5827:   fprintf(ficlog,"\n");
1.218     brouard  5828:        
1.126     brouard  5829:   free_vector(xm,1,npar);
                   5830:   free_vector(xp,1,npar);
                   5831:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5832:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5833:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5834: }
1.218     brouard  5835:  
1.126     brouard  5836: /************ Variance ******************/
1.235     brouard  5837:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5838:  {
1.279     brouard  5839:    /** Variance of health expectancies 
                   5840:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5841:     * double **newm;
                   5842:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5843:     */
1.218     brouard  5844:   
                   5845:    /* int movingaverage(); */
                   5846:    double **dnewm,**doldm;
                   5847:    double **dnewmp,**doldmp;
                   5848:    int i, j, nhstepm, hstepm, h, nstepm ;
                   5849:    int k;
                   5850:    double *xp;
1.279     brouard  5851:    double **gp, **gm;  /**< for var eij */
                   5852:    double ***gradg, ***trgradg; /**< for var eij */
                   5853:    double **gradgp, **trgradgp; /**< for var p point j */
                   5854:    double *gpp, *gmp; /**< for var p point j */
                   5855:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5856:    double ***p3mat;
                   5857:    double age,agelim, hf;
                   5858:    /* double ***mobaverage; */
                   5859:    int theta;
                   5860:    char digit[4];
                   5861:    char digitp[25];
                   5862: 
                   5863:    char fileresprobmorprev[FILENAMELENGTH];
                   5864: 
                   5865:    if(popbased==1){
                   5866:      if(mobilav!=0)
                   5867:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5868:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5869:    }
                   5870:    else 
                   5871:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5872: 
1.218     brouard  5873:    /* if (mobilav!=0) { */
                   5874:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5875:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5876:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5877:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5878:    /*   } */
                   5879:    /* } */
                   5880: 
                   5881:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5882:    sprintf(digit,"%-d",ij);
                   5883:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5884:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5885:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5886:    strcat(fileresprobmorprev,fileresu);
                   5887:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5888:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5889:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5890:    }
                   5891:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5892:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5893:    pstamp(ficresprobmorprev);
                   5894:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5895:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5896:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5897:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5898:    }
                   5899:    for(j=1;j<=cptcoveff;j++) 
                   5900:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5901:    fprintf(ficresprobmorprev,"\n");
                   5902: 
1.218     brouard  5903:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5904:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5905:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5906:      for(i=1; i<=nlstate;i++)
                   5907:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5908:    }  
                   5909:    fprintf(ficresprobmorprev,"\n");
                   5910:   
                   5911:    fprintf(ficgp,"\n# Routine varevsij");
                   5912:    fprintf(ficgp,"\nunset title \n");
                   5913:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5914:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5915:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5916: 
1.218     brouard  5917:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5918:    pstamp(ficresvij);
                   5919:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5920:    if(popbased==1)
                   5921:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5922:    else
                   5923:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5924:    fprintf(ficresvij,"# Age");
                   5925:    for(i=1; i<=nlstate;i++)
                   5926:      for(j=1; j<=nlstate;j++)
                   5927:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5928:    fprintf(ficresvij,"\n");
                   5929: 
                   5930:    xp=vector(1,npar);
                   5931:    dnewm=matrix(1,nlstate,1,npar);
                   5932:    doldm=matrix(1,nlstate,1,nlstate);
                   5933:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5934:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5935: 
                   5936:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5937:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5938:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5939:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5940:   
1.218     brouard  5941:    if(estepm < stepm){
                   5942:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5943:    }
                   5944:    else  hstepm=estepm;   
                   5945:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5946:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5947:       nhstepm is the number of hstepm from age to agelim 
                   5948:       nstepm is the number of stepm from age to agelim. 
                   5949:       Look at function hpijx to understand why because of memory size limitations, 
                   5950:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5951:       survival function given by stepm (the optimization length). Unfortunately it
                   5952:       means that if the survival funtion is printed every two years of age and if
                   5953:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5954:       results. So we changed our mind and took the option of the best precision.
                   5955:    */
                   5956:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5957:    agelim = AGESUP;
                   5958:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5959:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5960:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5961:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5962:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5963:      gp=matrix(0,nhstepm,1,nlstate);
                   5964:      gm=matrix(0,nhstepm,1,nlstate);
                   5965:                
                   5966:                
                   5967:      for(theta=1; theta <=npar; theta++){
                   5968:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5969:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5970:        }
1.279     brouard  5971:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   5972:        * returns into prlim .
                   5973:        */              
1.242     brouard  5974:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  5975: 
                   5976:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  5977:        if (popbased==1) {
                   5978:         if(mobilav ==0){
                   5979:           for(i=1; i<=nlstate;i++)
                   5980:             prlim[i][i]=probs[(int)age][i][ij];
                   5981:         }else{ /* mobilav */ 
                   5982:           for(i=1; i<=nlstate;i++)
                   5983:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5984:         }
                   5985:        }
1.279     brouard  5986:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}_x\f$ at horizon h.
                   5987:        */                      
                   5988:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
                   5989:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}_x\f$, which are the probability
                   5990:        * at horizon h in state j including mortality.
                   5991:        */
1.218     brouard  5992:        for(j=1; j<= nlstate; j++){
                   5993:         for(h=0; h<=nhstepm; h++){
                   5994:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   5995:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   5996:         }
                   5997:        }
1.279     brouard  5998:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  5999:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6000:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6001:        */
                   6002:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6003:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6004:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6005:        }
                   6006:        
                   6007:        /* Again with minus shift */
1.218     brouard  6008:                        
                   6009:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6010:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6011:                        
1.242     brouard  6012:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6013:                        
                   6014:        if (popbased==1) {
                   6015:         if(mobilav ==0){
                   6016:           for(i=1; i<=nlstate;i++)
                   6017:             prlim[i][i]=probs[(int)age][i][ij];
                   6018:         }else{ /* mobilav */ 
                   6019:           for(i=1; i<=nlstate;i++)
                   6020:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6021:         }
                   6022:        }
                   6023:                        
1.235     brouard  6024:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6025:                        
                   6026:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6027:         for(h=0; h<=nhstepm; h++){
                   6028:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6029:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6030:         }
                   6031:        }
                   6032:        /* This for computing probability of death (h=1 means
                   6033:          computed over hstepm matrices product = hstepm*stepm months) 
                   6034:          as a weighted average of prlim.
                   6035:        */
                   6036:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6037:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6038:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6039:        }    
1.279     brouard  6040:        /* end shifting computations */
                   6041: 
                   6042:        /**< Computing gradient matrix at horizon h 
                   6043:        */
1.218     brouard  6044:        for(j=1; j<= nlstate; j++) /* vareij */
                   6045:         for(h=0; h<=nhstepm; h++){
                   6046:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6047:         }
1.279     brouard  6048:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6049:        */
                   6050:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6051:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6052:        }
                   6053:                        
                   6054:      } /* End theta */
1.279     brouard  6055:      
                   6056:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6057:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6058:                
                   6059:      for(h=0; h<=nhstepm; h++) /* veij */
                   6060:        for(j=1; j<=nlstate;j++)
                   6061:         for(theta=1; theta <=npar; theta++)
                   6062:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6063:                
                   6064:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6065:        for(theta=1; theta <=npar; theta++)
                   6066:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6067:      /**< as well as its transposed matrix 
                   6068:       */               
1.218     brouard  6069:                
                   6070:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6071:      for(i=1;i<=nlstate;i++)
                   6072:        for(j=1;j<=nlstate;j++)
                   6073:         vareij[i][j][(int)age] =0.;
1.279     brouard  6074: 
                   6075:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6076:       * and k (nhstepm) formula 15 of article
                   6077:       * Lievre-Brouard-Heathcote
                   6078:       */
                   6079:      
1.218     brouard  6080:      for(h=0;h<=nhstepm;h++){
                   6081:        for(k=0;k<=nhstepm;k++){
                   6082:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6083:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6084:         for(i=1;i<=nlstate;i++)
                   6085:           for(j=1;j<=nlstate;j++)
                   6086:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6087:        }
                   6088:      }
                   6089:                
1.279     brouard  6090:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6091:       * p.j overall mortality formula 49 but computed directly because
                   6092:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6093:       * wix is independent of theta.
                   6094:       */
1.218     brouard  6095:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6096:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6097:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6098:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6099:         varppt[j][i]=doldmp[j][i];
                   6100:      /* end ppptj */
                   6101:      /*  x centered again */
                   6102:                
1.242     brouard  6103:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6104:                
                   6105:      if (popbased==1) {
                   6106:        if(mobilav ==0){
                   6107:         for(i=1; i<=nlstate;i++)
                   6108:           prlim[i][i]=probs[(int)age][i][ij];
                   6109:        }else{ /* mobilav */ 
                   6110:         for(i=1; i<=nlstate;i++)
                   6111:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6112:        }
                   6113:      }
                   6114:                
                   6115:      /* This for computing probability of death (h=1 means
                   6116:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6117:        as a weighted average of prlim.
                   6118:      */
1.235     brouard  6119:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6120:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6121:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6122:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6123:      }    
                   6124:      /* end probability of death */
                   6125:                
                   6126:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6127:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6128:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6129:        for(i=1; i<=nlstate;i++){
                   6130:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6131:        }
                   6132:      } 
                   6133:      fprintf(ficresprobmorprev,"\n");
                   6134:                
                   6135:      fprintf(ficresvij,"%.0f ",age );
                   6136:      for(i=1; i<=nlstate;i++)
                   6137:        for(j=1; j<=nlstate;j++){
                   6138:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6139:        }
                   6140:      fprintf(ficresvij,"\n");
                   6141:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6142:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6143:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6144:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6145:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6146:    } /* End age */
                   6147:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6148:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6149:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6150:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6151:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6152:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6153:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6154:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6155:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6156:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6157:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6158:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6159:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6160:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6161:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6162:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6163:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6164:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6165:     */
1.218     brouard  6166:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6167:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6168: 
1.218     brouard  6169:    free_vector(xp,1,npar);
                   6170:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6171:    free_matrix(dnewm,1,nlstate,1,npar);
                   6172:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6173:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6174:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6175:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6176:    fclose(ficresprobmorprev);
                   6177:    fflush(ficgp);
                   6178:    fflush(fichtm); 
                   6179:  }  /* end varevsij */
1.126     brouard  6180: 
                   6181: /************ Variance of prevlim ******************/
1.269     brouard  6182:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6183: {
1.205     brouard  6184:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6185:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6186: 
1.268     brouard  6187:   double **dnewmpar,**doldm;
1.126     brouard  6188:   int i, j, nhstepm, hstepm;
                   6189:   double *xp;
                   6190:   double *gp, *gm;
                   6191:   double **gradg, **trgradg;
1.208     brouard  6192:   double **mgm, **mgp;
1.126     brouard  6193:   double age,agelim;
                   6194:   int theta;
                   6195:   
                   6196:   pstamp(ficresvpl);
                   6197:   fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
1.241     brouard  6198:   fprintf(ficresvpl,"# Age ");
                   6199:   if(nresult >=1)
                   6200:     fprintf(ficresvpl," Result# ");
1.126     brouard  6201:   for(i=1; i<=nlstate;i++)
                   6202:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6203:   fprintf(ficresvpl,"\n");
                   6204: 
                   6205:   xp=vector(1,npar);
1.268     brouard  6206:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6207:   doldm=matrix(1,nlstate,1,nlstate);
                   6208:   
                   6209:   hstepm=1*YEARM; /* Every year of age */
                   6210:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6211:   agelim = AGESUP;
                   6212:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6213:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6214:     if (stepm >= YEARM) hstepm=1;
                   6215:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6216:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6217:     mgp=matrix(1,npar,1,nlstate);
                   6218:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6219:     gp=vector(1,nlstate);
                   6220:     gm=vector(1,nlstate);
                   6221: 
                   6222:     for(theta=1; theta <=npar; theta++){
                   6223:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6224:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6225:       }
1.209     brouard  6226:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6227:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6228:       else
1.235     brouard  6229:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6230:       for(i=1;i<=nlstate;i++){
1.126     brouard  6231:        gp[i] = prlim[i][i];
1.208     brouard  6232:        mgp[theta][i] = prlim[i][i];
                   6233:       }
1.126     brouard  6234:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6235:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.209     brouard  6236:       if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
1.235     brouard  6237:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.209     brouard  6238:       else
1.235     brouard  6239:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6240:       for(i=1;i<=nlstate;i++){
1.126     brouard  6241:        gm[i] = prlim[i][i];
1.208     brouard  6242:        mgm[theta][i] = prlim[i][i];
                   6243:       }
1.126     brouard  6244:       for(i=1;i<=nlstate;i++)
                   6245:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6246:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6247:     } /* End theta */
                   6248: 
                   6249:     trgradg =matrix(1,nlstate,1,npar);
                   6250: 
                   6251:     for(j=1; j<=nlstate;j++)
                   6252:       for(theta=1; theta <=npar; theta++)
                   6253:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6254:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6255:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6256:     /*   for(j=1; j<=nlstate;j++){ */
                   6257:     /*         printf(" %d ",j); */
                   6258:     /*         for(theta=1; theta <=npar; theta++) */
                   6259:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6260:     /*         printf("\n "); */
                   6261:     /*   } */
                   6262:     /* } */
                   6263:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6264:     /*   printf("\n gradg %d ",(int)age); */
                   6265:     /*   for(j=1; j<=nlstate;j++){ */
                   6266:     /*         printf("%d ",j); */
                   6267:     /*         for(theta=1; theta <=npar; theta++) */
                   6268:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6269:     /*         printf("\n "); */
                   6270:     /*   } */
                   6271:     /* } */
1.126     brouard  6272: 
                   6273:     for(i=1;i<=nlstate;i++)
                   6274:       varpl[i][(int)age] =0.;
1.209     brouard  6275:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6276:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6277:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6278:     }else{
1.268     brouard  6279:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6280:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6281:     }
1.126     brouard  6282:     for(i=1;i<=nlstate;i++)
                   6283:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6284: 
                   6285:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6286:     if(nresult >=1)
                   6287:       fprintf(ficresvpl,"%d ",nres );
1.126     brouard  6288:     for(i=1; i<=nlstate;i++)
                   6289:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
                   6290:     fprintf(ficresvpl,"\n");
                   6291:     free_vector(gp,1,nlstate);
                   6292:     free_vector(gm,1,nlstate);
1.208     brouard  6293:     free_matrix(mgm,1,npar,1,nlstate);
                   6294:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6295:     free_matrix(gradg,1,npar,1,nlstate);
                   6296:     free_matrix(trgradg,1,nlstate,1,npar);
                   6297:   } /* End age */
                   6298: 
                   6299:   free_vector(xp,1,npar);
                   6300:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6301:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6302: 
                   6303: }
                   6304: 
                   6305: 
                   6306: /************ Variance of backprevalence limit ******************/
1.269     brouard  6307:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6308: {
                   6309:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6310:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6311: 
                   6312:   double **dnewmpar,**doldm;
                   6313:   int i, j, nhstepm, hstepm;
                   6314:   double *xp;
                   6315:   double *gp, *gm;
                   6316:   double **gradg, **trgradg;
                   6317:   double **mgm, **mgp;
                   6318:   double age,agelim;
                   6319:   int theta;
                   6320:   
                   6321:   pstamp(ficresvbl);
                   6322:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6323:   fprintf(ficresvbl,"# Age ");
                   6324:   if(nresult >=1)
                   6325:     fprintf(ficresvbl," Result# ");
                   6326:   for(i=1; i<=nlstate;i++)
                   6327:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6328:   fprintf(ficresvbl,"\n");
                   6329: 
                   6330:   xp=vector(1,npar);
                   6331:   dnewmpar=matrix(1,nlstate,1,npar);
                   6332:   doldm=matrix(1,nlstate,1,nlstate);
                   6333:   
                   6334:   hstepm=1*YEARM; /* Every year of age */
                   6335:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6336:   agelim = AGEINF;
                   6337:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6338:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6339:     if (stepm >= YEARM) hstepm=1;
                   6340:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6341:     gradg=matrix(1,npar,1,nlstate);
                   6342:     mgp=matrix(1,npar,1,nlstate);
                   6343:     mgm=matrix(1,npar,1,nlstate);
                   6344:     gp=vector(1,nlstate);
                   6345:     gm=vector(1,nlstate);
                   6346: 
                   6347:     for(theta=1; theta <=npar; theta++){
                   6348:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6349:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6350:       }
                   6351:       if(mobilavproj > 0 )
                   6352:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6353:       else
                   6354:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6355:       for(i=1;i<=nlstate;i++){
                   6356:        gp[i] = bprlim[i][i];
                   6357:        mgp[theta][i] = bprlim[i][i];
                   6358:       }
                   6359:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6360:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6361:        if(mobilavproj > 0 )
                   6362:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6363:        else
                   6364:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6365:       for(i=1;i<=nlstate;i++){
                   6366:        gm[i] = bprlim[i][i];
                   6367:        mgm[theta][i] = bprlim[i][i];
                   6368:       }
                   6369:       for(i=1;i<=nlstate;i++)
                   6370:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6371:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6372:     } /* End theta */
                   6373: 
                   6374:     trgradg =matrix(1,nlstate,1,npar);
                   6375: 
                   6376:     for(j=1; j<=nlstate;j++)
                   6377:       for(theta=1; theta <=npar; theta++)
                   6378:        trgradg[j][theta]=gradg[theta][j];
                   6379:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6380:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6381:     /*   for(j=1; j<=nlstate;j++){ */
                   6382:     /*         printf(" %d ",j); */
                   6383:     /*         for(theta=1; theta <=npar; theta++) */
                   6384:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6385:     /*         printf("\n "); */
                   6386:     /*   } */
                   6387:     /* } */
                   6388:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6389:     /*   printf("\n gradg %d ",(int)age); */
                   6390:     /*   for(j=1; j<=nlstate;j++){ */
                   6391:     /*         printf("%d ",j); */
                   6392:     /*         for(theta=1; theta <=npar; theta++) */
                   6393:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6394:     /*         printf("\n "); */
                   6395:     /*   } */
                   6396:     /* } */
                   6397: 
                   6398:     for(i=1;i<=nlstate;i++)
                   6399:       varbpl[i][(int)age] =0.;
                   6400:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6401:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6402:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6403:     }else{
                   6404:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6405:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6406:     }
                   6407:     for(i=1;i<=nlstate;i++)
                   6408:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6409: 
                   6410:     fprintf(ficresvbl,"%.0f ",age );
                   6411:     if(nresult >=1)
                   6412:       fprintf(ficresvbl,"%d ",nres );
                   6413:     for(i=1; i<=nlstate;i++)
                   6414:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6415:     fprintf(ficresvbl,"\n");
                   6416:     free_vector(gp,1,nlstate);
                   6417:     free_vector(gm,1,nlstate);
                   6418:     free_matrix(mgm,1,npar,1,nlstate);
                   6419:     free_matrix(mgp,1,npar,1,nlstate);
                   6420:     free_matrix(gradg,1,npar,1,nlstate);
                   6421:     free_matrix(trgradg,1,nlstate,1,npar);
                   6422:   } /* End age */
                   6423: 
                   6424:   free_vector(xp,1,npar);
                   6425:   free_matrix(doldm,1,nlstate,1,npar);
                   6426:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6427: 
                   6428: }
                   6429: 
                   6430: /************ Variance of one-step probabilities  ******************/
                   6431: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6432:  {
                   6433:    int i, j=0,  k1, l1, tj;
                   6434:    int k2, l2, j1,  z1;
                   6435:    int k=0, l;
                   6436:    int first=1, first1, first2;
                   6437:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6438:    double **dnewm,**doldm;
                   6439:    double *xp;
                   6440:    double *gp, *gm;
                   6441:    double **gradg, **trgradg;
                   6442:    double **mu;
                   6443:    double age, cov[NCOVMAX+1];
                   6444:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6445:    int theta;
                   6446:    char fileresprob[FILENAMELENGTH];
                   6447:    char fileresprobcov[FILENAMELENGTH];
                   6448:    char fileresprobcor[FILENAMELENGTH];
                   6449:    double ***varpij;
                   6450: 
                   6451:    strcpy(fileresprob,"PROB_"); 
                   6452:    strcat(fileresprob,fileres);
                   6453:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6454:      printf("Problem with resultfile: %s\n", fileresprob);
                   6455:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6456:    }
                   6457:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6458:    strcat(fileresprobcov,fileresu);
                   6459:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6460:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6461:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6462:    }
                   6463:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6464:    strcat(fileresprobcor,fileresu);
                   6465:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6466:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6467:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6468:    }
                   6469:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6470:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6471:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6472:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6473:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6474:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6475:    pstamp(ficresprob);
                   6476:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6477:    fprintf(ficresprob,"# Age");
                   6478:    pstamp(ficresprobcov);
                   6479:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6480:    fprintf(ficresprobcov,"# Age");
                   6481:    pstamp(ficresprobcor);
                   6482:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6483:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6484: 
                   6485: 
1.222     brouard  6486:    for(i=1; i<=nlstate;i++)
                   6487:      for(j=1; j<=(nlstate+ndeath);j++){
                   6488:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6489:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6490:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6491:      }  
                   6492:    /* fprintf(ficresprob,"\n");
                   6493:       fprintf(ficresprobcov,"\n");
                   6494:       fprintf(ficresprobcor,"\n");
                   6495:    */
                   6496:    xp=vector(1,npar);
                   6497:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6498:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6499:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6500:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6501:    first=1;
                   6502:    fprintf(ficgp,"\n# Routine varprob");
                   6503:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6504:    fprintf(fichtm,"\n");
                   6505: 
1.266     brouard  6506:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6507:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6508:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6509: and drawn. It helps understanding how is the covariance between two incidences.\
                   6510:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6511:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6512: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6513: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6514: standard deviations wide on each axis. <br>\
                   6515:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6516:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6517: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6518: 
1.222     brouard  6519:    cov[1]=1;
                   6520:    /* tj=cptcoveff; */
1.225     brouard  6521:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6522:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6523:    j1=0;
1.224     brouard  6524:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6525:      if  (cptcovn>0) {
                   6526:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6527:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6528:        fprintf(ficresprob, "**********\n#\n");
                   6529:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6530:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6531:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6532:                        
1.222     brouard  6533:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6534:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6535:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6536:                        
                   6537:                        
1.222     brouard  6538:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6539:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6540:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6541:                        
1.222     brouard  6542:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6543:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6544:        fprintf(ficresprobcor, "**********\n#");    
                   6545:        if(invalidvarcomb[j1]){
                   6546:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6547:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6548:         continue;
                   6549:        }
                   6550:      }
                   6551:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6552:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6553:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6554:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6555:      for (age=bage; age<=fage; age ++){ 
                   6556:        cov[2]=age;
                   6557:        if(nagesqr==1)
                   6558:         cov[3]= age*age;
                   6559:        for (k=1; k<=cptcovn;k++) {
                   6560:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6561:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6562:                                                                    * 1  1 1 1 1
                   6563:                                                                    * 2  2 1 1 1
                   6564:                                                                    * 3  1 2 1 1
                   6565:                                                                    */
                   6566:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6567:        }
                   6568:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6569:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6570:        for (k=1; k<=cptcovprod;k++)
                   6571:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6572:                        
                   6573:                        
1.222     brouard  6574:        for(theta=1; theta <=npar; theta++){
                   6575:         for(i=1; i<=npar; i++)
                   6576:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6577:                                
1.222     brouard  6578:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6579:                                
1.222     brouard  6580:         k=0;
                   6581:         for(i=1; i<= (nlstate); i++){
                   6582:           for(j=1; j<=(nlstate+ndeath);j++){
                   6583:             k=k+1;
                   6584:             gp[k]=pmmij[i][j];
                   6585:           }
                   6586:         }
1.220     brouard  6587:                                
1.222     brouard  6588:         for(i=1; i<=npar; i++)
                   6589:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6590:                                
1.222     brouard  6591:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6592:         k=0;
                   6593:         for(i=1; i<=(nlstate); i++){
                   6594:           for(j=1; j<=(nlstate+ndeath);j++){
                   6595:             k=k+1;
                   6596:             gm[k]=pmmij[i][j];
                   6597:           }
                   6598:         }
1.220     brouard  6599:                                
1.222     brouard  6600:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6601:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6602:        }
1.126     brouard  6603: 
1.222     brouard  6604:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6605:         for(theta=1; theta <=npar; theta++)
                   6606:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6607:                        
1.222     brouard  6608:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6609:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6610:                        
1.222     brouard  6611:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6612:                        
1.222     brouard  6613:        k=0;
                   6614:        for(i=1; i<=(nlstate); i++){
                   6615:         for(j=1; j<=(nlstate+ndeath);j++){
                   6616:           k=k+1;
                   6617:           mu[k][(int) age]=pmmij[i][j];
                   6618:         }
                   6619:        }
                   6620:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6621:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6622:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6623:                        
1.222     brouard  6624:        /*printf("\n%d ",(int)age);
                   6625:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6626:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6627:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6628:         }*/
1.220     brouard  6629:                        
1.222     brouard  6630:        fprintf(ficresprob,"\n%d ",(int)age);
                   6631:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6632:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6633:                        
1.222     brouard  6634:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6635:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6636:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6637:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6638:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6639:        }
                   6640:        i=0;
                   6641:        for (k=1; k<=(nlstate);k++){
                   6642:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6643:           i++;
                   6644:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6645:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6646:           for (j=1; j<=i;j++){
                   6647:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6648:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6649:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6650:           }
                   6651:         }
                   6652:        }/* end of loop for state */
                   6653:      } /* end of loop for age */
                   6654:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6655:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6656:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6657:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6658:     
                   6659:      /* Confidence intervalle of pij  */
                   6660:      /*
                   6661:        fprintf(ficgp,"\nunset parametric;unset label");
                   6662:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6663:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6664:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6665:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6666:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6667:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6668:      */
                   6669:                
                   6670:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6671:      first1=1;first2=2;
                   6672:      for (k2=1; k2<=(nlstate);k2++){
                   6673:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6674:         if(l2==k2) continue;
                   6675:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6676:         for (k1=1; k1<=(nlstate);k1++){
                   6677:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6678:             if(l1==k1) continue;
                   6679:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6680:             if(i<=j) continue;
                   6681:             for (age=bage; age<=fage; age ++){ 
                   6682:               if ((int)age %5==0){
                   6683:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6684:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6685:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6686:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6687:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6688:                 c12=cv12/sqrt(v1*v2);
                   6689:                 /* Computing eigen value of matrix of covariance */
                   6690:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6691:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6692:                 if ((lc2 <0) || (lc1 <0) ){
                   6693:                   if(first2==1){
                   6694:                     first1=0;
                   6695:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6696:                   }
                   6697:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6698:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6699:                   /* lc2=fabs(lc2); */
                   6700:                 }
1.220     brouard  6701:                                                                
1.222     brouard  6702:                 /* Eigen vectors */
1.280     brouard  6703:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6704:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6705:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6706:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6707:                 }else
                   6708:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6709:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6710:                 v21=(lc1-v1)/cv12*v11;
                   6711:                 v12=-v21;
                   6712:                 v22=v11;
                   6713:                 tnalp=v21/v11;
                   6714:                 if(first1==1){
                   6715:                   first1=0;
                   6716:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6717:                 }
                   6718:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6719:                 /*printf(fignu*/
                   6720:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6721:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6722:                 if(first==1){
                   6723:                   first=0;
                   6724:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6725:                   fprintf(ficgp,"\nset parametric;unset label");
                   6726:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6727:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6728:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6729:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6730: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6731:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6732:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6733:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6734:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6735:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6736:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6737:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6738:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6739:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6740:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6741:                 }else{
                   6742:                   first=0;
                   6743:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6744:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6745:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6746:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6747:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6748:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6749:                 }/* if first */
                   6750:               } /* age mod 5 */
                   6751:             } /* end loop age */
                   6752:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6753:             first=1;
                   6754:           } /*l12 */
                   6755:         } /* k12 */
                   6756:        } /*l1 */
                   6757:      }/* k1 */
                   6758:    }  /* loop on combination of covariates j1 */
                   6759:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6760:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6761:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6762:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6763:    free_vector(xp,1,npar);
                   6764:    fclose(ficresprob);
                   6765:    fclose(ficresprobcov);
                   6766:    fclose(ficresprobcor);
                   6767:    fflush(ficgp);
                   6768:    fflush(fichtmcov);
                   6769:  }
1.126     brouard  6770: 
                   6771: 
                   6772: /******************* Printing html file ***********/
1.201     brouard  6773: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6774:                  int lastpass, int stepm, int weightopt, char model[],\
                   6775:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6776:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6777:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6778:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6779:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6780: 
                   6781:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6782:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6783: </ul>");
1.237     brouard  6784:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6785: </ul>", model);
1.214     brouard  6786:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6787:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6788:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6789:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6790:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6791:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6792:    fprintf(fichtm,"\
                   6793:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6794:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6795:    fprintf(fichtm,"\
1.217     brouard  6796:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6797:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6798:    fprintf(fichtm,"\
1.126     brouard  6799:  - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6800:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6801:    fprintf(fichtm,"\
1.217     brouard  6802:  - Period (stable) back prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
                   6803:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6804:    fprintf(fichtm,"\
1.211     brouard  6805:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6806:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6807:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6808:    if(prevfcast==1){
                   6809:      fprintf(fichtm,"\
                   6810:  - Prevalence projections by age and states:                           \
1.201     brouard  6811:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6812:    }
1.126     brouard  6813: 
                   6814: 
1.225     brouard  6815:    m=pow(2,cptcoveff);
1.222     brouard  6816:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6817: 
1.264     brouard  6818:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6819: 
                   6820:    jj1=0;
                   6821: 
                   6822:    fprintf(fichtm," \n<ul>");
                   6823:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6824:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6825:      if(m != 1 && TKresult[nres]!= k1)
                   6826:        continue;
                   6827:      jj1++;
                   6828:      if (cptcovn > 0) {
                   6829:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6830:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6831:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6832:        }
                   6833:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6834:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6835:        }
                   6836:        fprintf(fichtm,"\">");
                   6837:        
                   6838:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6839:        fprintf(fichtm,"************ Results for covariates");
                   6840:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6841:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6842:        }
                   6843:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6844:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6845:        }
                   6846:        if(invalidvarcomb[k1]){
                   6847:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6848:         continue;
                   6849:        }
                   6850:        fprintf(fichtm,"</a></li>");
                   6851:      } /* cptcovn >0 */
                   6852:    }
                   6853:      fprintf(fichtm," \n</ul>");
                   6854: 
1.222     brouard  6855:    jj1=0;
1.237     brouard  6856: 
                   6857:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6858:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6859:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6860:        continue;
1.220     brouard  6861: 
1.222     brouard  6862:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6863:      jj1++;
                   6864:      if (cptcovn > 0) {
1.264     brouard  6865:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6866:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6867:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6868:        }
                   6869:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6870:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6871:        }
                   6872:        fprintf(fichtm,"\"</a>");
                   6873:  
1.222     brouard  6874:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6875:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6876:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6877:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6878:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6879:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6880:        }
1.237     brouard  6881:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6882:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6883:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6884:       }
                   6885:        
1.230     brouard  6886:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6887:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6888:        if(invalidvarcomb[k1]){
                   6889:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6890:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6891:         continue;
                   6892:        }
                   6893:      }
                   6894:      /* aij, bij */
1.259     brouard  6895:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6896: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6897:      /* Pij */
1.241     brouard  6898:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6899: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6900:      /* Quasi-incidences */
                   6901:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6902:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6903:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6904: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6905: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6906:      /* Survival functions (period) in state j */
                   6907:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6908:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6909: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6910:      }
                   6911:      /* State specific survival functions (period) */
                   6912:      for(cpt=1; cpt<=nlstate;cpt++){
                   6913:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6914:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.283     brouard  6915:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6916:      }
                   6917:      /* Period (stable) prevalence in each health state */
                   6918:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6919:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6920: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6921:      }
                   6922:      if(backcast==1){
                   6923:        /* Period (stable) back prevalence in each health state */
                   6924:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6925:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6926: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6927:        }
1.217     brouard  6928:      }
1.222     brouard  6929:      if(prevfcast==1){
                   6930:        /* Projection of prevalence up to period (stable) prevalence in each health state */
                   6931:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6932:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6933: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6934:        }
                   6935:      }
1.268     brouard  6936:      if(backcast==1){
                   6937:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6938:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6939:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6940:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6941:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6942: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6943:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6944:        }
                   6945:      }
1.220     brouard  6946:         
1.222     brouard  6947:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6948:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6949: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6950:      }
                   6951:      /* } /\* end i1 *\/ */
                   6952:    }/* End k1 */
                   6953:    fprintf(fichtm,"</ul>");
1.126     brouard  6954: 
1.222     brouard  6955:    fprintf(fichtm,"\
1.126     brouard  6956: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6957:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6958:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6959: But because parameters are usually highly correlated (a higher incidence of disability \
                   6960: and a higher incidence of recovery can give very close observed transition) it might \
                   6961: be very useful to look not only at linear confidence intervals estimated from the \
                   6962: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6963: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6964: covariance matrix of the one-step probabilities. \
                   6965: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6966: 
1.222     brouard  6967:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6968:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6969:    fprintf(fichtm,"\
1.126     brouard  6970:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6971:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6972: 
1.222     brouard  6973:    fprintf(fichtm,"\
1.126     brouard  6974:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6975:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6976:    fprintf(fichtm,"\
1.126     brouard  6977:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6978:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6979:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6980:    fprintf(fichtm,"\
1.126     brouard  6981:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6982:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6983:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6984:    fprintf(fichtm,"\
1.128     brouard  6985:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6986:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6987:    fprintf(fichtm,"\
1.128     brouard  6988:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6989:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   6990:    fprintf(fichtm,"\
1.126     brouard  6991:  - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  6992:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  6993: 
                   6994: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   6995: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   6996: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   6997: /*     <br>",fileres,fileres,fileres,fileres); */
                   6998: /*  else  */
                   6999: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7000:    fflush(fichtm);
                   7001:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7002: 
1.225     brouard  7003:    m=pow(2,cptcoveff);
1.222     brouard  7004:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7005: 
1.222     brouard  7006:    jj1=0;
1.237     brouard  7007: 
1.241     brouard  7008:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7009:    for(k1=1; k1<=m;k1++){
1.253     brouard  7010:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7011:        continue;
1.222     brouard  7012:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7013:      jj1++;
1.126     brouard  7014:      if (cptcovn > 0) {
                   7015:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7016:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7017:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7018:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7019:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7020:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7021:       }
                   7022: 
1.126     brouard  7023:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7024: 
1.222     brouard  7025:        if(invalidvarcomb[k1]){
                   7026:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7027:         continue;
                   7028:        }
1.126     brouard  7029:      }
                   7030:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7031:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7032: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7033: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7034:      }
                   7035:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7036: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7037: true period expectancies (those weighted with period prevalences are also\
                   7038:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7039:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7040: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7041:      /* } /\* end i1 *\/ */
                   7042:    }/* End k1 */
1.241     brouard  7043:   }/* End nres */
1.222     brouard  7044:    fprintf(fichtm,"</ul>");
                   7045:    fflush(fichtm);
1.126     brouard  7046: }
                   7047: 
                   7048: /******************* Gnuplot file **************/
1.270     brouard  7049: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7050: 
                   7051:   char dirfileres[132],optfileres[132];
1.264     brouard  7052:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7053:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7054:   int lv=0, vlv=0, kl=0;
1.130     brouard  7055:   int ng=0;
1.201     brouard  7056:   int vpopbased;
1.223     brouard  7057:   int ioffset; /* variable offset for columns */
1.270     brouard  7058:   int iyearc=1; /* variable column for year of projection  */
                   7059:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7060:   int nres=0; /* Index of resultline */
1.266     brouard  7061:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7062: 
1.126     brouard  7063: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7064: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7065: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7066: /*   } */
                   7067: 
                   7068:   /*#ifdef windows */
                   7069:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7070:   /*#endif */
1.225     brouard  7071:   m=pow(2,cptcoveff);
1.126     brouard  7072: 
1.274     brouard  7073:   /* diagram of the model */
                   7074:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7075:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7076:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7077:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7078: 
                   7079:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7080:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7081:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7082:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7083:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7084:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7085:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7086: 
1.202     brouard  7087:   /* Contribution to likelihood */
                   7088:   /* Plot the probability implied in the likelihood */
1.223     brouard  7089:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7090:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7091:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7092:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7093: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7094:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7095: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7096:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7097:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7098:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7099:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7100:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7101:   for (i=1; i<= nlstate ; i ++) {
                   7102:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7103:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7104:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7105:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7106:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7107:     }
                   7108:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7109:   }
                   7110:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7111:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7112:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7113:   fprintf(ficgp,"\nset out;unset log\n");
                   7114:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7115: 
1.126     brouard  7116:   strcpy(dirfileres,optionfilefiname);
                   7117:   strcpy(optfileres,"vpl");
1.223     brouard  7118:   /* 1eme*/
1.238     brouard  7119:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7120:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7121:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7122:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7123:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7124:          continue;
                   7125:        /* We are interested in selected combination by the resultline */
1.246     brouard  7126:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.238     brouard  7127:        fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7128:        strcpy(gplotlabel,"(");
1.238     brouard  7129:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7130:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7131:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7132:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7133:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7134:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7135:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7136:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7137:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7138:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7139:        }
                   7140:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7141:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7142:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7143:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7144:        }
                   7145:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7146:        /* printf("\n#\n"); */
1.238     brouard  7147:        fprintf(ficgp,"\n#\n");
                   7148:        if(invalidvarcomb[k1]){
1.260     brouard  7149:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7150:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7151:          continue;
                   7152:        }
1.235     brouard  7153:       
1.241     brouard  7154:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7155:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7156:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7157:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7158:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7159:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7160:       /* k1-1 error should be nres-1*/
1.238     brouard  7161:        for (i=1; i<= nlstate ; i ++) {
                   7162:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7163:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7164:        }
1.260     brouard  7165:        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7166:        for (i=1; i<= nlstate ; i ++) {
                   7167:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7168:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7169:        } 
1.260     brouard  7170:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7171:        for (i=1; i<= nlstate ; i ++) {
                   7172:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7173:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7174:        }  
1.265     brouard  7175:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7176:        
                   7177:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7178:         if(cptcoveff ==0){
1.271     brouard  7179:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7180:        }else{
                   7181:          kl=0;
                   7182:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7183:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7184:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7185:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7186:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7187:            vlv= nbcode[Tvaraff[k]][lv];
                   7188:            kl++;
                   7189:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7190:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7191:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7192:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7193:            if(k==cptcoveff){
                   7194:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7195:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7196:            }else{
                   7197:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7198:              kl++;
                   7199:            }
                   7200:          } /* end covariate */
                   7201:        } /* end if no covariate */
                   7202: 
1.238     brouard  7203:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7204:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7205:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7206:          if(cptcoveff ==0){
1.245     brouard  7207:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7208:          }else{
                   7209:            kl=0;
                   7210:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7211:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7212:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7213:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7214:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7215:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7216:              kl++;
1.238     brouard  7217:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7218:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7219:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7220:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7221:              if(k==cptcoveff){
1.245     brouard  7222:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7223:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7224:              }else{
                   7225:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7226:                kl++;
                   7227:              }
                   7228:            } /* end covariate */
                   7229:          } /* end if no covariate */
1.268     brouard  7230:          if(backcast == 1){
                   7231:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7232:            /* k1-1 error should be nres-1*/
                   7233:            for (i=1; i<= nlstate ; i ++) {
                   7234:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7235:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7236:            }
1.271     brouard  7237:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7238:            for (i=1; i<= nlstate ; i ++) {
                   7239:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7240:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7241:            } 
1.276     brouard  7242:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7243:            for (i=1; i<= nlstate ; i ++) {
                   7244:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7245:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7246:            } 
1.274     brouard  7247:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7248:          } /* end if backprojcast */
1.238     brouard  7249:        } /* end if backcast */
1.276     brouard  7250:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7251:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7252:       } /* nres */
1.201     brouard  7253:     } /* k1 */
                   7254:   } /* cpt */
1.235     brouard  7255: 
                   7256:   
1.126     brouard  7257:   /*2 eme*/
1.238     brouard  7258:   for (k1=1; k1<= m ; k1 ++){  
                   7259:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7260:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7261:        continue;
                   7262:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7263:       strcpy(gplotlabel,"(");
1.238     brouard  7264:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7265:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7266:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7267:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7268:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7269:        vlv= nbcode[Tvaraff[k]][lv];
                   7270:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7271:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7272:       }
1.237     brouard  7273:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7274:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7275:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7276:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7277:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7278:       }
1.264     brouard  7279:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7280:       fprintf(ficgp,"\n#\n");
1.223     brouard  7281:       if(invalidvarcomb[k1]){
                   7282:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7283:        continue;
                   7284:       }
1.219     brouard  7285:                        
1.241     brouard  7286:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7287:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7288:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7289:        if(vpopbased==0){
1.238     brouard  7290:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7291:        }else
1.238     brouard  7292:          fprintf(ficgp,"\nreplot ");
                   7293:        for (i=1; i<= nlstate+1 ; i ++) {
                   7294:          k=2*i;
1.261     brouard  7295:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7296:          for (j=1; j<= nlstate+1 ; j ++) {
                   7297:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7298:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7299:          }   
                   7300:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7301:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7302:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7303:          for (j=1; j<= nlstate+1 ; j ++) {
                   7304:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7305:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7306:          }   
                   7307:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7308:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7309:          for (j=1; j<= nlstate+1 ; j ++) {
                   7310:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7311:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7312:          }   
                   7313:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7314:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7315:        } /* state */
                   7316:       } /* vpopbased */
1.264     brouard  7317:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7318:     } /* end nres */
                   7319:   } /* k1 end 2 eme*/
                   7320:        
                   7321:        
                   7322:   /*3eme*/
                   7323:   for (k1=1; k1<= m ; k1 ++){
                   7324:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7325:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7326:        continue;
                   7327: 
                   7328:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7329:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7330:        strcpy(gplotlabel,"(");
1.238     brouard  7331:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7332:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7333:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7334:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7335:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7336:          vlv= nbcode[Tvaraff[k]][lv];
                   7337:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7338:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7339:        }
                   7340:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7341:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7342:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7343:        }       
1.264     brouard  7344:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7345:        fprintf(ficgp,"\n#\n");
                   7346:        if(invalidvarcomb[k1]){
                   7347:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7348:          continue;
                   7349:        }
                   7350:                        
                   7351:        /*       k=2+nlstate*(2*cpt-2); */
                   7352:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7353:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7354:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7355:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7356: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7357:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7358:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7359:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7360:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7361:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7362:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7363:                                
1.238     brouard  7364:        */
                   7365:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7366:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7367:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7368:                                
1.238     brouard  7369:        } 
1.261     brouard  7370:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7371:       }
1.264     brouard  7372:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7373:     } /* end nres */
                   7374:   } /* end kl 3eme */
1.126     brouard  7375:   
1.223     brouard  7376:   /* 4eme */
1.201     brouard  7377:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7378:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7379:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7380:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7381:        continue;
1.238     brouard  7382:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7383:        strcpy(gplotlabel,"(");
1.238     brouard  7384:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7385:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7386:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7387:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7388:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7389:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7390:          vlv= nbcode[Tvaraff[k]][lv];
                   7391:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7392:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7393:        }
                   7394:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7395:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7396:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7397:        }       
1.264     brouard  7398:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7399:        fprintf(ficgp,"\n#\n");
                   7400:        if(invalidvarcomb[k1]){
                   7401:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7402:          continue;
1.223     brouard  7403:        }
1.238     brouard  7404:       
1.241     brouard  7405:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7406:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7407:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7408: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7409:        k=3;
                   7410:        for (i=1; i<= nlstate ; i ++){
                   7411:          if(i==1){
                   7412:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7413:          }else{
                   7414:            fprintf(ficgp,", '' ");
                   7415:          }
                   7416:          l=(nlstate+ndeath)*(i-1)+1;
                   7417:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7418:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7419:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7420:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7421:        } /* nlstate */
1.264     brouard  7422:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7423:       } /* end cpt state*/ 
                   7424:     } /* end nres */
                   7425:   } /* end covariate k1 */  
                   7426: 
1.220     brouard  7427: /* 5eme */
1.201     brouard  7428:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7429:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7430:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7431:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7432:        continue;
1.238     brouard  7433:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7434:        strcpy(gplotlabel,"(");
1.238     brouard  7435:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7436:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7437:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7438:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7439:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7440:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7441:          vlv= nbcode[Tvaraff[k]][lv];
                   7442:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7443:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7444:        }
                   7445:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7446:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7447:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7448:        }       
1.264     brouard  7449:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7450:        fprintf(ficgp,"\n#\n");
                   7451:        if(invalidvarcomb[k1]){
                   7452:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7453:          continue;
                   7454:        }
1.227     brouard  7455:       
1.241     brouard  7456:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7457:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7458:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7459: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7460:        k=3;
                   7461:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7462:          if(j==1)
                   7463:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7464:          else
                   7465:            fprintf(ficgp,", '' ");
                   7466:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7467:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7468:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7469:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7470:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7471:        } /* nlstate */
                   7472:        fprintf(ficgp,", '' ");
                   7473:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7474:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7475:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7476:          if(j < nlstate)
                   7477:            fprintf(ficgp,"$%d +",k+l);
                   7478:          else
                   7479:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7480:        }
1.264     brouard  7481:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7482:       } /* end cpt state*/ 
                   7483:     } /* end covariate */  
                   7484:   } /* end nres */
1.227     brouard  7485:   
1.220     brouard  7486: /* 6eme */
1.202     brouard  7487:   /* CV preval stable (period) for each covariate */
1.237     brouard  7488:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7489:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7490:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7491:       continue;
1.255     brouard  7492:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7493:       strcpy(gplotlabel,"(");      
1.211     brouard  7494:       fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7495:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7496:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7497:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7498:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7499:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7500:        vlv= nbcode[Tvaraff[k]][lv];
                   7501:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7502:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7503:       }
1.237     brouard  7504:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7505:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7506:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7507:       }        
1.264     brouard  7508:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7509:       fprintf(ficgp,"\n#\n");
1.223     brouard  7510:       if(invalidvarcomb[k1]){
1.227     brouard  7511:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7512:        continue;
1.223     brouard  7513:       }
1.227     brouard  7514:       
1.241     brouard  7515:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7516:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7517:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7518: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7519:       k=3; /* Offset */
1.255     brouard  7520:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7521:        if(i==1)
                   7522:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7523:        else
                   7524:          fprintf(ficgp,", '' ");
1.255     brouard  7525:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7526:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7527:        for (j=2; j<= nlstate ; j ++)
                   7528:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7529:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7530:       } /* nlstate */
1.264     brouard  7531:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7532:     } /* end cpt state*/ 
                   7533:   } /* end covariate */  
1.227     brouard  7534:   
                   7535:   
1.220     brouard  7536: /* 7eme */
1.218     brouard  7537:   if(backcast == 1){
1.217     brouard  7538:     /* CV back preval stable (period) for each covariate */
1.237     brouard  7539:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7540:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7541:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7542:        continue;
1.268     brouard  7543:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7544:        strcpy(gplotlabel,"(");      
                   7545:        fprintf(ficgp,"\n#\n#\n#CV Back preval stable (period): 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7546:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7547:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7548:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7549:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7550:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7551:          vlv= nbcode[Tvaraff[k]][lv];
                   7552:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7553:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7554:        }
1.237     brouard  7555:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7556:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7557:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7558:        }       
1.264     brouard  7559:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7560:        fprintf(ficgp,"\n#\n");
                   7561:        if(invalidvarcomb[k1]){
                   7562:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7563:          continue;
                   7564:        }
                   7565:        
1.241     brouard  7566:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7567:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7568:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7569: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7570:        k=3; /* Offset */
1.268     brouard  7571:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7572:          if(i==1)
                   7573:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7574:          else
                   7575:            fprintf(ficgp,", '' ");
                   7576:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7577:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7578:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7579:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7580:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7581:          /* for (j=2; j<= nlstate ; j ++) */
                   7582:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7583:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7584:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7585:        } /* nlstate */
1.264     brouard  7586:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7587:       } /* end cpt state*/ 
                   7588:     } /* end covariate */  
                   7589:   } /* End if backcast */
                   7590:   
1.223     brouard  7591:   /* 8eme */
1.218     brouard  7592:   if(prevfcast==1){
                   7593:     /* Projection from cross-sectional to stable (period) for each covariate */
                   7594:     
1.237     brouard  7595:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7596:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7597:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7598:        continue;
1.211     brouard  7599:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7600:        strcpy(gplotlabel,"(");      
1.227     brouard  7601:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to stable (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
                   7602:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7603:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7604:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7605:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7606:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7607:          vlv= nbcode[Tvaraff[k]][lv];
                   7608:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7609:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7610:        }
1.237     brouard  7611:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7612:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7613:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7614:        }       
1.264     brouard  7615:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7616:        fprintf(ficgp,"\n#\n");
                   7617:        if(invalidvarcomb[k1]){
                   7618:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7619:          continue;
                   7620:        }
                   7621:        
                   7622:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7623:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7624:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7625:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7626: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7627: 
                   7628:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7629:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7630:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7631:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7632:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7633:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7634:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7635:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7636:          if(i==istart){
1.227     brouard  7637:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7638:          }else{
                   7639:            fprintf(ficgp,",\\\n '' ");
                   7640:          }
                   7641:          if(cptcoveff ==0){ /* No covariate */
                   7642:            ioffset=2; /* Age is in 2 */
                   7643:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7644:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7645:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7646:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7647:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7648:            if(i==nlstate+1){
1.270     brouard  7649:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7650:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7651:              fprintf(ficgp,",\\\n '' ");
                   7652:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7653:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7654:                     offyear,                           \
1.268     brouard  7655:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7656:            }else
1.227     brouard  7657:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7658:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7659:          }else{ /* more than 2 covariates */
1.270     brouard  7660:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7661:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7662:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7663:            iyearc=ioffset-1;
                   7664:            iagec=ioffset;
1.227     brouard  7665:            fprintf(ficgp," u %d:(",ioffset); 
                   7666:            kl=0;
                   7667:            strcpy(gplotcondition,"(");
                   7668:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7669:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7670:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7671:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7672:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7673:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7674:              kl++;
                   7675:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7676:              kl++;
                   7677:              if(k <cptcoveff && cptcoveff>1)
                   7678:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7679:            }
                   7680:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7681:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7682:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7683:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7684:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7685:            if(i==nlstate+1){
1.270     brouard  7686:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7687:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7688:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7689:              fprintf(ficgp," u %d:(",iagec); 
                   7690:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7691:                      iyearc, iagec, offyear,                           \
                   7692:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7693: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7694:            }else{
                   7695:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7696:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7697:            }
                   7698:          } /* end if covariate */
                   7699:        } /* nlstate */
1.264     brouard  7700:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7701:       } /* end cpt state*/
                   7702:     } /* end covariate */
                   7703:   } /* End if prevfcast */
1.227     brouard  7704:   
1.268     brouard  7705:   if(backcast==1){
                   7706:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7707:     
                   7708:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7709:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7710:       if(m != 1 && TKresult[nres]!= k1)
                   7711:        continue;
                   7712:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7713:        strcpy(gplotlabel,"(");      
                   7714:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7715:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7716:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7717:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7718:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7719:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7720:          vlv= nbcode[Tvaraff[k]][lv];
                   7721:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7722:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7723:        }
                   7724:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7725:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7726:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7727:        }       
                   7728:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7729:        fprintf(ficgp,"\n#\n");
                   7730:        if(invalidvarcomb[k1]){
                   7731:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7732:          continue;
                   7733:        }
                   7734:        
                   7735:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7736:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7737:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7738:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7739: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7740: 
                   7741:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7742:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7743:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7744:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7745:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7746:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7747:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7748:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7749:          if(i==istart){
                   7750:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7751:          }else{
                   7752:            fprintf(ficgp,",\\\n '' ");
                   7753:          }
                   7754:          if(cptcoveff ==0){ /* No covariate */
                   7755:            ioffset=2; /* Age is in 2 */
                   7756:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7757:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7758:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7759:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7760:            fprintf(ficgp," u %d:(", ioffset); 
                   7761:            if(i==nlstate+1){
1.270     brouard  7762:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7763:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7764:              fprintf(ficgp,",\\\n '' ");
                   7765:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7766:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7767:                     offbyear,                          \
                   7768:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7769:            }else
                   7770:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7771:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7772:          }else{ /* more than 2 covariates */
1.270     brouard  7773:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7774:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7775:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7776:            iyearc=ioffset-1;
                   7777:            iagec=ioffset;
1.268     brouard  7778:            fprintf(ficgp," u %d:(",ioffset); 
                   7779:            kl=0;
                   7780:            strcpy(gplotcondition,"(");
                   7781:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7782:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7783:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7784:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7785:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7786:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7787:              kl++;
                   7788:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7789:              kl++;
                   7790:              if(k <cptcoveff && cptcoveff>1)
                   7791:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7792:            }
                   7793:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7794:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7795:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7796:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7797:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7798:            if(i==nlstate+1){
1.270     brouard  7799:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7800:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7801:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7802:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7803:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7804:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7805:                      iyearc,iagec,offbyear,                            \
                   7806:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7807: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7808:            }else{
                   7809:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7810:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7811:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7812:            }
                   7813:          } /* end if covariate */
                   7814:        } /* nlstate */
                   7815:        fprintf(ficgp,"\nset out; unset label;\n");
                   7816:       } /* end cpt state*/
                   7817:     } /* end covariate */
                   7818:   } /* End if backcast */
                   7819:   
1.227     brouard  7820:   
1.238     brouard  7821:   /* 9eme writing MLE parameters */
                   7822:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7823:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7824:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7825:     for(k=1; k <=(nlstate+ndeath); k++){
                   7826:       if (k != i) {
1.227     brouard  7827:        fprintf(ficgp,"#   current state %d\n",k);
                   7828:        for(j=1; j <=ncovmodel; j++){
                   7829:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7830:          jk++; 
                   7831:        }
                   7832:        fprintf(ficgp,"\n");
1.126     brouard  7833:       }
                   7834:     }
1.223     brouard  7835:   }
1.187     brouard  7836:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7837:   
1.145     brouard  7838:   /*goto avoid;*/
1.238     brouard  7839:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7840:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7841:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7842:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7843:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7844:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7845:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7846:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7847:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7848:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7849:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7850:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7851:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7852:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7853:   fprintf(ficgp,"#\n");
1.223     brouard  7854:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7855:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7856:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7857:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7858:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7859:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7860:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7861:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7862:        continue;
1.264     brouard  7863:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7864:       strcpy(gplotlabel,"(");
1.276     brouard  7865:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7866:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7867:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7868:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7869:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7870:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7871:        vlv= nbcode[Tvaraff[k]][lv];
                   7872:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7873:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7874:       }
1.237     brouard  7875:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7876:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7877:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7878:       }        
1.264     brouard  7879:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7880:       fprintf(ficgp,"\n#\n");
1.264     brouard  7881:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7882:       fprintf(ficgp,"\nset key outside ");
                   7883:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7884:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7885:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7886:       if (ng==1){
                   7887:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7888:        fprintf(ficgp,"\nunset log y");
                   7889:       }else if (ng==2){
                   7890:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7891:        fprintf(ficgp,"\nset log y");
                   7892:       }else if (ng==3){
                   7893:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7894:        fprintf(ficgp,"\nset log y");
                   7895:       }else
                   7896:        fprintf(ficgp,"\nunset title ");
                   7897:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7898:       i=1;
                   7899:       for(k2=1; k2<=nlstate; k2++) {
                   7900:        k3=i;
                   7901:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7902:          if (k != k2){
                   7903:            switch( ng) {
                   7904:            case 1:
                   7905:              if(nagesqr==0)
                   7906:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7907:              else /* nagesqr =1 */
                   7908:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7909:              break;
                   7910:            case 2: /* ng=2 */
                   7911:              if(nagesqr==0)
                   7912:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7913:              else /* nagesqr =1 */
                   7914:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7915:              break;
                   7916:            case 3:
                   7917:              if(nagesqr==0)
                   7918:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7919:              else /* nagesqr =1 */
                   7920:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7921:              break;
                   7922:            }
                   7923:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7924:            ijp=1; /* product no age */
                   7925:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7926:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7927:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7928:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7929:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7930:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7931:                    if(DummyV[j]==0){
                   7932:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7933:                    }else{ /* quantitative */
                   7934:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7935:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7936:                    }
                   7937:                    ij++;
1.237     brouard  7938:                  }
1.268     brouard  7939:                } 
                   7940:              }else if(cptcovprod >0){
                   7941:                if(j==Tprod[ijp]) { /* */ 
                   7942:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7943:                  if(ijp <=cptcovprod) { /* Product */
                   7944:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7945:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7946:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7947:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7948:                      }else{ /* Vn is dummy and Vm is quanti */
                   7949:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7950:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7951:                      }
                   7952:                    }else{ /* Vn*Vm Vn is quanti */
                   7953:                      if(DummyV[Tvard[ijp][2]]==0){
                   7954:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7955:                      }else{ /* Both quanti */
                   7956:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7957:                      }
1.237     brouard  7958:                    }
1.268     brouard  7959:                    ijp++;
1.237     brouard  7960:                  }
1.268     brouard  7961:                } /* end Tprod */
1.237     brouard  7962:              } else{  /* simple covariate */
1.264     brouard  7963:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7964:                if(Dummy[j]==0){
                   7965:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7966:                }else{ /* quantitative */
                   7967:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7968:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7969:                }
1.237     brouard  7970:              } /* end simple */
                   7971:            } /* end j */
1.223     brouard  7972:          }else{
                   7973:            i=i-ncovmodel;
                   7974:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7975:              fprintf(ficgp," (1.");
                   7976:          }
1.227     brouard  7977:          
1.223     brouard  7978:          if(ng != 1){
                   7979:            fprintf(ficgp,")/(1");
1.227     brouard  7980:            
1.264     brouard  7981:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7982:              if(nagesqr==0)
1.264     brouard  7983:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7984:              else /* nagesqr =1 */
1.264     brouard  7985:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7986:               
1.223     brouard  7987:              ij=1;
                   7988:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  7989:                 if(cptcovage >0){ 
                   7990:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   7991:                     if(ij <=cptcovage) { /* Bug valgrind */
                   7992:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   7993:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7994:                       ij++;
                   7995:                     }
                   7996:                   }
                   7997:                 }else
                   7998:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  7999:              }
                   8000:              fprintf(ficgp,")");
                   8001:            }
                   8002:            fprintf(ficgp,")");
                   8003:            if(ng ==2)
1.276     brouard  8004:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8005:            else /* ng= 3 */
1.276     brouard  8006:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8007:          }else{ /* end ng <> 1 */
                   8008:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8009:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8010:          }
                   8011:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8012:            fprintf(ficgp,",");
                   8013:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8014:            fprintf(ficgp,",");
                   8015:          i=i+ncovmodel;
                   8016:        } /* end k */
                   8017:       } /* end k2 */
1.276     brouard  8018:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8019:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8020:     } /* end k1 */
1.223     brouard  8021:   } /* end ng */
                   8022:   /* avoid: */
                   8023:   fflush(ficgp); 
1.126     brouard  8024: }  /* end gnuplot */
                   8025: 
                   8026: 
                   8027: /*************** Moving average **************/
1.219     brouard  8028: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8029:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8030:    
1.222     brouard  8031:    int i, cpt, cptcod;
                   8032:    int modcovmax =1;
                   8033:    int mobilavrange, mob;
                   8034:    int iage=0;
                   8035: 
1.266     brouard  8036:    double sum=0., sumr=0.;
1.222     brouard  8037:    double age;
1.266     brouard  8038:    double *sumnewp, *sumnewm, *sumnewmr;
                   8039:    double *agemingood, *agemaxgood; 
                   8040:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8041:   
                   8042:   
1.278     brouard  8043:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8044:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8045: 
                   8046:    sumnewp = vector(1,ncovcombmax);
                   8047:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8048:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8049:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8050:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8051:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8052:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8053: 
                   8054:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8055:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8056:      sumnewp[cptcod]=0.;
1.266     brouard  8057:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8058:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8059:    }
                   8060:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8061:   
1.266     brouard  8062:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8063:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8064:      else mobilavrange=mobilav;
                   8065:      for (age=bage; age<=fage; age++)
                   8066:        for (i=1; i<=nlstate;i++)
                   8067:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8068:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8069:      /* We keep the original values on the extreme ages bage, fage and for 
                   8070:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8071:        we use a 5 terms etc. until the borders are no more concerned. 
                   8072:      */ 
                   8073:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8074:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8075:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8076:           sumnewm[cptcod]=0.;
                   8077:           for (i=1; i<=nlstate;i++){
1.222     brouard  8078:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8079:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8080:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8081:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8082:             }
                   8083:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8084:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8085:           } /* end i */
                   8086:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8087:         } /* end cptcod */
1.222     brouard  8088:        }/* end age */
                   8089:      }/* end mob */
1.266     brouard  8090:    }else{
                   8091:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8092:      return -1;
1.266     brouard  8093:    }
                   8094: 
                   8095:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8096:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8097:      if(invalidvarcomb[cptcod]){
                   8098:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8099:        continue;
                   8100:      }
1.219     brouard  8101: 
1.266     brouard  8102:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8103:        sumnewm[cptcod]=0.;
                   8104:        sumnewmr[cptcod]=0.;
                   8105:        for (i=1; i<=nlstate;i++){
                   8106:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8107:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8108:        }
                   8109:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8110:         agemingoodr[cptcod]=age;
                   8111:        }
                   8112:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8113:           agemingood[cptcod]=age;
                   8114:        }
                   8115:      } /* age */
                   8116:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8117:        sumnewm[cptcod]=0.;
1.266     brouard  8118:        sumnewmr[cptcod]=0.;
1.222     brouard  8119:        for (i=1; i<=nlstate;i++){
                   8120:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8121:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8122:        }
                   8123:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8124:         agemaxgoodr[cptcod]=age;
1.222     brouard  8125:        }
                   8126:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8127:         agemaxgood[cptcod]=age;
                   8128:        }
                   8129:      } /* age */
                   8130:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8131:      /* but they will change */
                   8132:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8133:        sumnewm[cptcod]=0.;
                   8134:        sumnewmr[cptcod]=0.;
                   8135:        for (i=1; i<=nlstate;i++){
                   8136:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8137:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8138:        }
                   8139:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8140:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8141:           agemaxgoodr[cptcod]=age;  /* age min */
                   8142:           for (i=1; i<=nlstate;i++)
                   8143:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8144:         }else{ /* bad we change the value with the values of good ages */
                   8145:           for (i=1; i<=nlstate;i++){
                   8146:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8147:           } /* i */
                   8148:         } /* end bad */
                   8149:        }else{
                   8150:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8151:           agemaxgood[cptcod]=age;
                   8152:         }else{ /* bad we change the value with the values of good ages */
                   8153:           for (i=1; i<=nlstate;i++){
                   8154:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8155:           } /* i */
                   8156:         } /* end bad */
                   8157:        }/* end else */
                   8158:        sum=0.;sumr=0.;
                   8159:        for (i=1; i<=nlstate;i++){
                   8160:         sum+=mobaverage[(int)age][i][cptcod];
                   8161:         sumr+=probs[(int)age][i][cptcod];
                   8162:        }
                   8163:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8164:         printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8165:        } /* end bad */
                   8166:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8167:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8168:         printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8169:        } /* end bad */
                   8170:      }/* age */
1.266     brouard  8171: 
                   8172:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8173:        sumnewm[cptcod]=0.;
1.266     brouard  8174:        sumnewmr[cptcod]=0.;
1.222     brouard  8175:        for (i=1; i<=nlstate;i++){
                   8176:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8177:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8178:        } 
                   8179:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8180:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8181:           agemingoodr[cptcod]=age;
                   8182:           for (i=1; i<=nlstate;i++)
                   8183:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8184:         }else{ /* bad we change the value with the values of good ages */
                   8185:           for (i=1; i<=nlstate;i++){
                   8186:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8187:           } /* i */
                   8188:         } /* end bad */
                   8189:        }else{
                   8190:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8191:           agemingood[cptcod]=age;
                   8192:         }else{ /* bad */
                   8193:           for (i=1; i<=nlstate;i++){
                   8194:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8195:           } /* i */
                   8196:         } /* end bad */
                   8197:        }/* end else */
                   8198:        sum=0.;sumr=0.;
                   8199:        for (i=1; i<=nlstate;i++){
                   8200:         sum+=mobaverage[(int)age][i][cptcod];
                   8201:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8202:        }
1.266     brouard  8203:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8204:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8205:        } /* end bad */
                   8206:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8207:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8208:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8209:        } /* end bad */
                   8210:      }/* age */
1.266     brouard  8211: 
1.222     brouard  8212:                
                   8213:      for (age=bage; age<=fage; age++){
1.235     brouard  8214:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8215:        sumnewp[cptcod]=0.;
                   8216:        sumnewm[cptcod]=0.;
                   8217:        for (i=1; i<=nlstate;i++){
                   8218:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8219:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8220:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8221:        }
                   8222:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8223:      }
                   8224:      /* printf("\n"); */
                   8225:      /* } */
1.266     brouard  8226: 
1.222     brouard  8227:      /* brutal averaging */
1.266     brouard  8228:      /* for (i=1; i<=nlstate;i++){ */
                   8229:      /*   for (age=1; age<=bage; age++){ */
                   8230:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8231:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8232:      /*   }     */
                   8233:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8234:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8235:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8236:      /*   } */
                   8237:      /* } /\* end i status *\/ */
                   8238:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8239:      /*   for (age=1; age<=AGESUP; age++){ */
                   8240:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8241:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8242:      /*   } */
                   8243:      /* } */
1.222     brouard  8244:    }/* end cptcod */
1.266     brouard  8245:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8246:    free_vector(agemaxgood,1, ncovcombmax);
                   8247:    free_vector(agemingood,1, ncovcombmax);
                   8248:    free_vector(agemingoodr,1, ncovcombmax);
                   8249:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8250:    free_vector(sumnewm,1, ncovcombmax);
                   8251:    free_vector(sumnewp,1, ncovcombmax);
                   8252:    return 0;
                   8253:  }/* End movingaverage */
1.218     brouard  8254:  
1.126     brouard  8255: 
                   8256: /************** Forecasting ******************/
1.269     brouard  8257:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8258:   /* proj1, year, month, day of starting projection 
                   8259:      agemin, agemax range of age
                   8260:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8261:      anproj2 year of en of projection (same day and month as proj1).
                   8262:   */
1.267     brouard  8263:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8264:   double agec; /* generic age */
                   8265:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8266:   double *popeffectif,*popcount;
                   8267:   double ***p3mat;
1.218     brouard  8268:   /* double ***mobaverage; */
1.126     brouard  8269:   char fileresf[FILENAMELENGTH];
                   8270: 
                   8271:   agelim=AGESUP;
1.211     brouard  8272:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8273:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8274:      We still use firstpass and lastpass as another selection.
                   8275:   */
1.214     brouard  8276:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8277:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8278:  
1.201     brouard  8279:   strcpy(fileresf,"F_"); 
                   8280:   strcat(fileresf,fileresu);
1.126     brouard  8281:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8282:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8283:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8284:   }
1.235     brouard  8285:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8286:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8287: 
1.225     brouard  8288:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8289: 
                   8290: 
                   8291:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8292:   if (stepm<=12) stepsize=1;
                   8293:   if(estepm < stepm){
                   8294:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8295:   }
1.270     brouard  8296:   else{
                   8297:     hstepm=estepm;   
                   8298:   }
                   8299:   if(estepm > stepm){ /* Yes every two year */
                   8300:     stepsize=2;
                   8301:   }
1.126     brouard  8302: 
                   8303:   hstepm=hstepm/stepm; 
                   8304:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8305:                                fractional in yp1 */
                   8306:   anprojmean=yp;
                   8307:   yp2=modf((yp1*12),&yp);
                   8308:   mprojmean=yp;
                   8309:   yp1=modf((yp2*30.5),&yp);
                   8310:   jprojmean=yp;
                   8311:   if(jprojmean==0) jprojmean=1;
                   8312:   if(mprojmean==0) jprojmean=1;
                   8313: 
1.227     brouard  8314:   i1=pow(2,cptcoveff);
1.126     brouard  8315:   if (cptcovn < 1){i1=1;}
                   8316:   
                   8317:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8318:   
                   8319:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8320:   
1.126     brouard  8321: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8322:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8323:   for(k=1; k<=i1;k++){
1.253     brouard  8324:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8325:       continue;
1.227     brouard  8326:     if(invalidvarcomb[k]){
                   8327:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8328:       continue;
                   8329:     }
                   8330:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8331:     for(j=1;j<=cptcoveff;j++) {
                   8332:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8333:     }
1.235     brouard  8334:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8335:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8336:     }
1.227     brouard  8337:     fprintf(ficresf," yearproj age");
                   8338:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8339:       for(i=1; i<=nlstate;i++)               
                   8340:        fprintf(ficresf," p%d%d",i,j);
                   8341:       fprintf(ficresf," wp.%d",j);
                   8342:     }
                   8343:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8344:       fprintf(ficresf,"\n");
                   8345:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8346:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8347:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8348:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8349:        nhstepm = nhstepm/hstepm; 
                   8350:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8351:        oldm=oldms;savm=savms;
1.268     brouard  8352:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8353:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8354:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8355:        for (h=0; h<=nhstepm; h++){
                   8356:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8357:            break;
                   8358:          }
                   8359:        }
                   8360:        fprintf(ficresf,"\n");
                   8361:        for(j=1;j<=cptcoveff;j++) 
                   8362:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8363:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8364:        
                   8365:        for(j=1; j<=nlstate+ndeath;j++) {
                   8366:          ppij=0.;
                   8367:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8368:            if (mobilav>=1)
                   8369:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8370:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8371:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8372:            }
1.268     brouard  8373:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8374:          } /* end i */
                   8375:          fprintf(ficresf," %.3f", ppij);
                   8376:        }/* end j */
1.227     brouard  8377:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8378:       } /* end agec */
1.266     brouard  8379:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8380:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8381:     } /* end yearp */
                   8382:   } /* end  k */
1.219     brouard  8383:        
1.126     brouard  8384:   fclose(ficresf);
1.215     brouard  8385:   printf("End of Computing forecasting \n");
                   8386:   fprintf(ficlog,"End of Computing forecasting\n");
                   8387: 
1.126     brouard  8388: }
                   8389: 
1.269     brouard  8390: /************** Back Forecasting ******************/
                   8391:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8392:   /* back1, year, month, day of starting backection
                   8393:      agemin, agemax range of age
                   8394:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8395:      anback2 year of end of backprojection (same day and month as back1).
                   8396:      prevacurrent and prev are prevalences.
1.267     brouard  8397:   */
                   8398:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8399:   double agec; /* generic age */
1.268     brouard  8400:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8401:   double *popeffectif,*popcount;
                   8402:   double ***p3mat;
                   8403:   /* double ***mobaverage; */
                   8404:   char fileresfb[FILENAMELENGTH];
                   8405:  
1.268     brouard  8406:   agelim=AGEINF;
1.267     brouard  8407:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8408:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8409:      We still use firstpass and lastpass as another selection.
                   8410:   */
                   8411:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8412:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8413: 
                   8414:   /*Do we need to compute prevalence again?*/
                   8415: 
                   8416:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8417:   
                   8418:   strcpy(fileresfb,"FB_");
                   8419:   strcat(fileresfb,fileresu);
                   8420:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8421:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8422:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8423:   }
                   8424:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8425:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8426:   
                   8427:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8428:   
                   8429:    
                   8430:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8431:   if (stepm<=12) stepsize=1;
                   8432:   if(estepm < stepm){
                   8433:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8434:   }
1.270     brouard  8435:   else{
                   8436:     hstepm=estepm;   
                   8437:   }
                   8438:   if(estepm >= stepm){ /* Yes every two year */
                   8439:     stepsize=2;
                   8440:   }
1.267     brouard  8441:   
                   8442:   hstepm=hstepm/stepm;
                   8443:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8444:                                fractional in yp1 */
                   8445:   anprojmean=yp;
                   8446:   yp2=modf((yp1*12),&yp);
                   8447:   mprojmean=yp;
                   8448:   yp1=modf((yp2*30.5),&yp);
                   8449:   jprojmean=yp;
                   8450:   if(jprojmean==0) jprojmean=1;
                   8451:   if(mprojmean==0) jprojmean=1;
                   8452:   
                   8453:   i1=pow(2,cptcoveff);
                   8454:   if (cptcovn < 1){i1=1;}
                   8455:   
                   8456:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8457:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8458:   
                   8459:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8460:   
                   8461:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8462:   for(k=1; k<=i1;k++){
                   8463:     if(i1 != 1 && TKresult[nres]!= k)
                   8464:       continue;
                   8465:     if(invalidvarcomb[k]){
                   8466:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8467:       continue;
                   8468:     }
1.268     brouard  8469:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8470:     for(j=1;j<=cptcoveff;j++) {
                   8471:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8472:     }
                   8473:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8474:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8475:     }
                   8476:     fprintf(ficresfb," yearbproj age");
                   8477:     for(j=1; j<=nlstate+ndeath;j++){
                   8478:       for(i=1; i<=nlstate;i++)
1.268     brouard  8479:        fprintf(ficresfb," b%d%d",i,j);
                   8480:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8481:     }
                   8482:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8483:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8484:       fprintf(ficresfb,"\n");
                   8485:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8486:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8487:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8488:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8489:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8490:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8491:        nhstepm = nhstepm/hstepm;
                   8492:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8493:        oldm=oldms;savm=savms;
1.268     brouard  8494:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8495:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8496:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8497:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8498:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8499:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8500:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8501:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8502:            break;
                   8503:          }
                   8504:        }
                   8505:        fprintf(ficresfb,"\n");
                   8506:        for(j=1;j<=cptcoveff;j++)
                   8507:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8508:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8509:        for(i=1; i<=nlstate+ndeath;i++) {
                   8510:          ppij=0.;ppi=0.;
                   8511:          for(j=1; j<=nlstate;j++) {
                   8512:            /* if (mobilav==1) */
1.269     brouard  8513:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8514:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8515:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8516:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8517:              /* else { */
                   8518:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8519:              /* } */
1.268     brouard  8520:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8521:          } /* end j */
                   8522:          if(ppi <0.99){
                   8523:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8524:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8525:          }
                   8526:          fprintf(ficresfb," %.3f", ppij);
                   8527:        }/* end j */
1.267     brouard  8528:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8529:       } /* end agec */
                   8530:     } /* end yearp */
                   8531:   } /* end k */
1.217     brouard  8532:   
1.267     brouard  8533:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8534:   
1.267     brouard  8535:   fclose(ficresfb);
                   8536:   printf("End of Computing Back forecasting \n");
                   8537:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8538:        
1.267     brouard  8539: }
1.217     brouard  8540: 
1.269     brouard  8541: /* Variance of prevalence limit: varprlim */
                   8542:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8543:     /*------- Variance of period (stable) prevalence------*/   
                   8544:  
                   8545:    char fileresvpl[FILENAMELENGTH];  
                   8546:    FILE *ficresvpl;
                   8547:    double **oldm, **savm;
                   8548:    double **varpl; /* Variances of prevalence limits by age */   
                   8549:    int i1, k, nres, j ;
                   8550:    
                   8551:     strcpy(fileresvpl,"VPL_");
                   8552:     strcat(fileresvpl,fileresu);
                   8553:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
                   8554:       printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
                   8555:       exit(0);
                   8556:     }
                   8557:     printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8558:     fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
                   8559:     
                   8560:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8561:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8562:     
                   8563:     i1=pow(2,cptcoveff);
                   8564:     if (cptcovn < 1){i1=1;}
                   8565: 
                   8566:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8567:     for(k=1; k<=i1;k++){
                   8568:       if(i1 != 1 && TKresult[nres]!= k)
                   8569:        continue;
                   8570:       fprintf(ficresvpl,"\n#****** ");
                   8571:       printf("\n#****** ");
                   8572:       fprintf(ficlog,"\n#****** ");
                   8573:       for(j=1;j<=cptcoveff;j++) {
                   8574:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8575:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8576:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8577:       }
                   8578:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8579:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8580:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8581:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8582:       }        
                   8583:       fprintf(ficresvpl,"******\n");
                   8584:       printf("******\n");
                   8585:       fprintf(ficlog,"******\n");
                   8586:       
                   8587:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8588:       oldm=oldms;savm=savms;
                   8589:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8590:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8591:       /*}*/
                   8592:     }
                   8593:     
                   8594:     fclose(ficresvpl);
                   8595:     printf("done variance-covariance of period prevalence\n");fflush(stdout);
                   8596:     fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
                   8597: 
                   8598:  }
                   8599: /* Variance of back prevalence: varbprlim */
                   8600:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8601:       /*------- Variance of back (stable) prevalence------*/
                   8602: 
                   8603:    char fileresvbl[FILENAMELENGTH];  
                   8604:    FILE  *ficresvbl;
                   8605: 
                   8606:    double **oldm, **savm;
                   8607:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8608:    int i1, k, nres, j ;
                   8609: 
                   8610:    strcpy(fileresvbl,"VBL_");
                   8611:    strcat(fileresvbl,fileresu);
                   8612:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8613:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8614:      exit(0);
                   8615:    }
                   8616:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8617:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8618:    
                   8619:    
                   8620:    i1=pow(2,cptcoveff);
                   8621:    if (cptcovn < 1){i1=1;}
                   8622:    
                   8623:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8624:      for(k=1; k<=i1;k++){
                   8625:        if(i1 != 1 && TKresult[nres]!= k)
                   8626:         continue;
                   8627:        fprintf(ficresvbl,"\n#****** ");
                   8628:        printf("\n#****** ");
                   8629:        fprintf(ficlog,"\n#****** ");
                   8630:        for(j=1;j<=cptcoveff;j++) {
                   8631:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8632:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8633:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8634:        }
                   8635:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8636:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8637:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8638:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8639:        }
                   8640:        fprintf(ficresvbl,"******\n");
                   8641:        printf("******\n");
                   8642:        fprintf(ficlog,"******\n");
                   8643:        
                   8644:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8645:        oldm=oldms;savm=savms;
                   8646:        
                   8647:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8648:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8649:        /*}*/
                   8650:      }
                   8651:    
                   8652:    fclose(ficresvbl);
                   8653:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8654:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8655: 
                   8656:  } /* End of varbprlim */
                   8657: 
1.126     brouard  8658: /************** Forecasting *****not tested NB*************/
1.227     brouard  8659: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8660:   
1.227     brouard  8661: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8662: /*   int *popage; */
                   8663: /*   double calagedatem, agelim, kk1, kk2; */
                   8664: /*   double *popeffectif,*popcount; */
                   8665: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8666: /*   /\* double ***mobaverage; *\/ */
                   8667: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8668: 
1.227     brouard  8669: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8670: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8671: /*   agelim=AGESUP; */
                   8672: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8673:   
1.227     brouard  8674: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8675:   
                   8676:   
1.227     brouard  8677: /*   strcpy(filerespop,"POP_");  */
                   8678: /*   strcat(filerespop,fileresu); */
                   8679: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8680: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8681: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8682: /*   } */
                   8683: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8684: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8685: 
1.227     brouard  8686: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8687: 
1.227     brouard  8688: /*   /\* if (mobilav!=0) { *\/ */
                   8689: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8690: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8691: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8692: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8693: /*   /\*   } *\/ */
                   8694: /*   /\* } *\/ */
1.126     brouard  8695: 
1.227     brouard  8696: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8697: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8698:   
1.227     brouard  8699: /*   agelim=AGESUP; */
1.126     brouard  8700:   
1.227     brouard  8701: /*   hstepm=1; */
                   8702: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8703:        
1.227     brouard  8704: /*   if (popforecast==1) { */
                   8705: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8706: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8707: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8708: /*     }  */
                   8709: /*     popage=ivector(0,AGESUP); */
                   8710: /*     popeffectif=vector(0,AGESUP); */
                   8711: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8712:     
1.227     brouard  8713: /*     i=1;    */
                   8714: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8715:     
1.227     brouard  8716: /*     imx=i; */
                   8717: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8718: /*   } */
1.218     brouard  8719:   
1.227     brouard  8720: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8721: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8722: /*       k=k+1; */
                   8723: /*       fprintf(ficrespop,"\n#******"); */
                   8724: /*       for(j=1;j<=cptcoveff;j++) { */
                   8725: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8726: /*       } */
                   8727: /*       fprintf(ficrespop,"******\n"); */
                   8728: /*       fprintf(ficrespop,"# Age"); */
                   8729: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8730: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8731:       
1.227     brouard  8732: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8733: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8734:        
1.227     brouard  8735: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8736: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8737: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8738:          
1.227     brouard  8739: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8740: /*       oldm=oldms;savm=savms; */
                   8741: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8742:          
1.227     brouard  8743: /*       for (h=0; h<=nhstepm; h++){ */
                   8744: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8745: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8746: /*         }  */
                   8747: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8748: /*           kk1=0.;kk2=0; */
                   8749: /*           for(i=1; i<=nlstate;i++) {               */
                   8750: /*             if (mobilav==1)  */
                   8751: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8752: /*             else { */
                   8753: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8754: /*             } */
                   8755: /*           } */
                   8756: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8757: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8758: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8759: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8760: /*           } */
                   8761: /*         } */
                   8762: /*         for(i=1; i<=nlstate;i++){ */
                   8763: /*           kk1=0.; */
                   8764: /*           for(j=1; j<=nlstate;j++){ */
                   8765: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8766: /*           } */
                   8767: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8768: /*         } */
1.218     brouard  8769:            
1.227     brouard  8770: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8771: /*           for(j=1; j<=nlstate;j++)  */
                   8772: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8773: /*       } */
                   8774: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8775: /*     } */
                   8776: /*       } */
1.218     brouard  8777:       
1.227     brouard  8778: /*       /\******\/ */
1.218     brouard  8779:       
1.227     brouard  8780: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8781: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8782: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8783: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8784: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8785:          
1.227     brouard  8786: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8787: /*       oldm=oldms;savm=savms; */
                   8788: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8789: /*       for (h=0; h<=nhstepm; h++){ */
                   8790: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8791: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8792: /*         }  */
                   8793: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8794: /*           kk1=0.;kk2=0; */
                   8795: /*           for(i=1; i<=nlstate;i++) {               */
                   8796: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8797: /*           } */
                   8798: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8799: /*         } */
                   8800: /*       } */
                   8801: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8802: /*     } */
                   8803: /*       } */
                   8804: /*     }  */
                   8805: /*   } */
1.218     brouard  8806:   
1.227     brouard  8807: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8808:   
1.227     brouard  8809: /*   if (popforecast==1) { */
                   8810: /*     free_ivector(popage,0,AGESUP); */
                   8811: /*     free_vector(popeffectif,0,AGESUP); */
                   8812: /*     free_vector(popcount,0,AGESUP); */
                   8813: /*   } */
                   8814: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8815: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8816: /*   fclose(ficrespop); */
                   8817: /* } /\* End of popforecast *\/ */
1.218     brouard  8818:  
1.126     brouard  8819: int fileappend(FILE *fichier, char *optionfich)
                   8820: {
                   8821:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8822:     printf("Problem with file: %s\n", optionfich);
                   8823:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8824:     return (0);
                   8825:   }
                   8826:   fflush(fichier);
                   8827:   return (1);
                   8828: }
                   8829: 
                   8830: 
                   8831: /**************** function prwizard **********************/
                   8832: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8833: {
                   8834: 
                   8835:   /* Wizard to print covariance matrix template */
                   8836: 
1.164     brouard  8837:   char ca[32], cb[32];
                   8838:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8839:   int numlinepar;
                   8840: 
                   8841:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8842:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8843:   for(i=1; i <=nlstate; i++){
                   8844:     jj=0;
                   8845:     for(j=1; j <=nlstate+ndeath; j++){
                   8846:       if(j==i) continue;
                   8847:       jj++;
                   8848:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8849:       printf("%1d%1d",i,j);
                   8850:       fprintf(ficparo,"%1d%1d",i,j);
                   8851:       for(k=1; k<=ncovmodel;k++){
                   8852:        /*        printf(" %lf",param[i][j][k]); */
                   8853:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8854:        printf(" 0.");
                   8855:        fprintf(ficparo," 0.");
                   8856:       }
                   8857:       printf("\n");
                   8858:       fprintf(ficparo,"\n");
                   8859:     }
                   8860:   }
                   8861:   printf("# Scales (for hessian or gradient estimation)\n");
                   8862:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8863:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8864:   for(i=1; i <=nlstate; i++){
                   8865:     jj=0;
                   8866:     for(j=1; j <=nlstate+ndeath; j++){
                   8867:       if(j==i) continue;
                   8868:       jj++;
                   8869:       fprintf(ficparo,"%1d%1d",i,j);
                   8870:       printf("%1d%1d",i,j);
                   8871:       fflush(stdout);
                   8872:       for(k=1; k<=ncovmodel;k++){
                   8873:        /*      printf(" %le",delti3[i][j][k]); */
                   8874:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8875:        printf(" 0.");
                   8876:        fprintf(ficparo," 0.");
                   8877:       }
                   8878:       numlinepar++;
                   8879:       printf("\n");
                   8880:       fprintf(ficparo,"\n");
                   8881:     }
                   8882:   }
                   8883:   printf("# Covariance matrix\n");
                   8884: /* # 121 Var(a12)\n\ */
                   8885: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8886: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8887: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8888: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8889: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8890: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8891: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8892:   fflush(stdout);
                   8893:   fprintf(ficparo,"# Covariance matrix\n");
                   8894:   /* # 121 Var(a12)\n\ */
                   8895:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8896:   /* #   ...\n\ */
                   8897:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8898:   
                   8899:   for(itimes=1;itimes<=2;itimes++){
                   8900:     jj=0;
                   8901:     for(i=1; i <=nlstate; i++){
                   8902:       for(j=1; j <=nlstate+ndeath; j++){
                   8903:        if(j==i) continue;
                   8904:        for(k=1; k<=ncovmodel;k++){
                   8905:          jj++;
                   8906:          ca[0]= k+'a'-1;ca[1]='\0';
                   8907:          if(itimes==1){
                   8908:            printf("#%1d%1d%d",i,j,k);
                   8909:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8910:          }else{
                   8911:            printf("%1d%1d%d",i,j,k);
                   8912:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8913:            /*  printf(" %.5le",matcov[i][j]); */
                   8914:          }
                   8915:          ll=0;
                   8916:          for(li=1;li <=nlstate; li++){
                   8917:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8918:              if(lj==li) continue;
                   8919:              for(lk=1;lk<=ncovmodel;lk++){
                   8920:                ll++;
                   8921:                if(ll<=jj){
                   8922:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8923:                  if(ll<jj){
                   8924:                    if(itimes==1){
                   8925:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8926:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8927:                    }else{
                   8928:                      printf(" 0.");
                   8929:                      fprintf(ficparo," 0.");
                   8930:                    }
                   8931:                  }else{
                   8932:                    if(itimes==1){
                   8933:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8934:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8935:                    }else{
                   8936:                      printf(" 0.");
                   8937:                      fprintf(ficparo," 0.");
                   8938:                    }
                   8939:                  }
                   8940:                }
                   8941:              } /* end lk */
                   8942:            } /* end lj */
                   8943:          } /* end li */
                   8944:          printf("\n");
                   8945:          fprintf(ficparo,"\n");
                   8946:          numlinepar++;
                   8947:        } /* end k*/
                   8948:       } /*end j */
                   8949:     } /* end i */
                   8950:   } /* end itimes */
                   8951: 
                   8952: } /* end of prwizard */
                   8953: /******************* Gompertz Likelihood ******************************/
                   8954: double gompertz(double x[])
                   8955: { 
                   8956:   double A,B,L=0.0,sump=0.,num=0.;
                   8957:   int i,n=0; /* n is the size of the sample */
                   8958: 
1.220     brouard  8959:   for (i=1;i<=imx ; i++) {
1.126     brouard  8960:     sump=sump+weight[i];
                   8961:     /*    sump=sump+1;*/
                   8962:     num=num+1;
                   8963:   }
                   8964:  
                   8965:  
                   8966:   /* for (i=0; i<=imx; i++) 
                   8967:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8968: 
                   8969:   for (i=1;i<=imx ; i++)
                   8970:     {
                   8971:       if (cens[i] == 1 && wav[i]>1)
                   8972:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8973:       
                   8974:       if (cens[i] == 0 && wav[i]>1)
                   8975:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8976:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8977:       
                   8978:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   8979:       if (wav[i] > 1 ) { /* ??? */
                   8980:        L=L+A*weight[i];
                   8981:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   8982:       }
                   8983:     }
                   8984: 
                   8985:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   8986:  
                   8987:   return -2*L*num/sump;
                   8988: }
                   8989: 
1.136     brouard  8990: #ifdef GSL
                   8991: /******************* Gompertz_f Likelihood ******************************/
                   8992: double gompertz_f(const gsl_vector *v, void *params)
                   8993: { 
                   8994:   double A,B,LL=0.0,sump=0.,num=0.;
                   8995:   double *x= (double *) v->data;
                   8996:   int i,n=0; /* n is the size of the sample */
                   8997: 
                   8998:   for (i=0;i<=imx-1 ; i++) {
                   8999:     sump=sump+weight[i];
                   9000:     /*    sump=sump+1;*/
                   9001:     num=num+1;
                   9002:   }
                   9003:  
                   9004:  
                   9005:   /* for (i=0; i<=imx; i++) 
                   9006:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9007:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9008:   for (i=1;i<=imx ; i++)
                   9009:     {
                   9010:       if (cens[i] == 1 && wav[i]>1)
                   9011:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9012:       
                   9013:       if (cens[i] == 0 && wav[i]>1)
                   9014:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9015:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9016:       
                   9017:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9018:       if (wav[i] > 1 ) { /* ??? */
                   9019:        LL=LL+A*weight[i];
                   9020:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9021:       }
                   9022:     }
                   9023: 
                   9024:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9025:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9026:  
                   9027:   return -2*LL*num/sump;
                   9028: }
                   9029: #endif
                   9030: 
1.126     brouard  9031: /******************* Printing html file ***********/
1.201     brouard  9032: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9033:                  int lastpass, int stepm, int weightopt, char model[],\
                   9034:                  int imx,  double p[],double **matcov,double agemortsup){
                   9035:   int i,k;
                   9036: 
                   9037:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9038:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9039:   for (i=1;i<=2;i++) 
                   9040:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9041:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9042:   fprintf(fichtm,"</ul>");
                   9043: 
                   9044: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9045: 
                   9046:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9047: 
                   9048:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9049:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9050: 
                   9051:  
                   9052:   fflush(fichtm);
                   9053: }
                   9054: 
                   9055: /******************* Gnuplot file **************/
1.201     brouard  9056: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9057: 
                   9058:   char dirfileres[132],optfileres[132];
1.164     brouard  9059: 
1.126     brouard  9060:   int ng;
                   9061: 
                   9062: 
                   9063:   /*#ifdef windows */
                   9064:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9065:     /*#endif */
                   9066: 
                   9067: 
                   9068:   strcpy(dirfileres,optionfilefiname);
                   9069:   strcpy(optfileres,"vpl");
1.199     brouard  9070:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9071:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9072:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9073:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9074:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9075: 
                   9076: } 
                   9077: 
1.136     brouard  9078: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9079: {
1.126     brouard  9080: 
1.136     brouard  9081:   /*-------- data file ----------*/
                   9082:   FILE *fic;
                   9083:   char dummy[]="                         ";
1.240     brouard  9084:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9085:   int lstra;
1.136     brouard  9086:   int linei, month, year,iout;
                   9087:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9088:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9089:   char *stratrunc;
1.223     brouard  9090: 
1.240     brouard  9091:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9092:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9093: 
1.240     brouard  9094:   for(v=1; v <=ncovcol;v++){
                   9095:     DummyV[v]=0;
                   9096:     FixedV[v]=0;
                   9097:   }
                   9098:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9099:     DummyV[v]=1;
                   9100:     FixedV[v]=0;
                   9101:   }
                   9102:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9103:     DummyV[v]=0;
                   9104:     FixedV[v]=1;
                   9105:   }
                   9106:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9107:     DummyV[v]=1;
                   9108:     FixedV[v]=1;
                   9109:   }
                   9110:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9111:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9112:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9113:   }
1.126     brouard  9114: 
1.136     brouard  9115:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9116:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9117:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9118:   }
1.126     brouard  9119: 
1.136     brouard  9120:   i=1;
                   9121:   linei=0;
                   9122:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9123:     linei=linei+1;
                   9124:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9125:       if(line[j] == '\t')
                   9126:        line[j] = ' ';
                   9127:     }
                   9128:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9129:       ;
                   9130:     };
                   9131:     line[j+1]=0;  /* Trims blanks at end of line */
                   9132:     if(line[0]=='#'){
                   9133:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9134:       printf("Comment line\n%s\n",line);
                   9135:       continue;
                   9136:     }
                   9137:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9138:     strcpy(line, linetmp);
1.223     brouard  9139:     
                   9140:     /* Loops on waves */
                   9141:     for (j=maxwav;j>=1;j--){
                   9142:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9143:        cutv(stra, strb, line, ' '); 
                   9144:        if(strb[0]=='.') { /* Missing value */
                   9145:          lval=-1;
                   9146:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9147:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9148:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9149:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9150:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9151:            return 1;
                   9152:          }
                   9153:        }else{
                   9154:          errno=0;
                   9155:          /* what_kind_of_number(strb); */
                   9156:          dval=strtod(strb,&endptr); 
                   9157:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9158:          /* if(strb != endptr && *endptr == '\0') */
                   9159:          /*    dval=dlval; */
                   9160:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9161:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9162:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9163:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9164:            return 1;
                   9165:          }
                   9166:          cotqvar[j][iv][i]=dval; 
                   9167:          cotvar[j][ntv+iv][i]=dval; 
                   9168:        }
                   9169:        strcpy(line,stra);
1.223     brouard  9170:       }/* end loop ntqv */
1.225     brouard  9171:       
1.223     brouard  9172:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9173:        cutv(stra, strb, line, ' '); 
                   9174:        if(strb[0]=='.') { /* Missing value */
                   9175:          lval=-1;
                   9176:        }else{
                   9177:          errno=0;
                   9178:          lval=strtol(strb,&endptr,10); 
                   9179:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9180:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9181:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9182:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9183:            return 1;
                   9184:          }
                   9185:        }
                   9186:        if(lval <-1 || lval >1){
                   9187:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9188:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9189:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9190:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9191:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9192:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9193:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9194:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9195:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9196:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9197:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9198:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9199:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9200:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9201:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9202:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9203:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9204:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9205:          return 1;
                   9206:        }
                   9207:        cotvar[j][iv][i]=(double)(lval);
                   9208:        strcpy(line,stra);
1.223     brouard  9209:       }/* end loop ntv */
1.225     brouard  9210:       
1.223     brouard  9211:       /* Statuses  at wave */
1.137     brouard  9212:       cutv(stra, strb, line, ' '); 
1.223     brouard  9213:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9214:        lval=-1;
1.136     brouard  9215:       }else{
1.238     brouard  9216:        errno=0;
                   9217:        lval=strtol(strb,&endptr,10); 
                   9218:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9219:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9220:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9221:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9222:          return 1;
                   9223:        }
1.136     brouard  9224:       }
1.225     brouard  9225:       
1.136     brouard  9226:       s[j][i]=lval;
1.225     brouard  9227:       
1.223     brouard  9228:       /* Date of Interview */
1.136     brouard  9229:       strcpy(line,stra);
                   9230:       cutv(stra, strb,line,' ');
1.169     brouard  9231:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9232:       }
1.169     brouard  9233:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9234:        month=99;
                   9235:        year=9999;
1.136     brouard  9236:       }else{
1.225     brouard  9237:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9238:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9239:        return 1;
1.136     brouard  9240:       }
                   9241:       anint[j][i]= (double) year; 
                   9242:       mint[j][i]= (double)month; 
                   9243:       strcpy(line,stra);
1.223     brouard  9244:     } /* End loop on waves */
1.225     brouard  9245:     
1.223     brouard  9246:     /* Date of death */
1.136     brouard  9247:     cutv(stra, strb,line,' '); 
1.169     brouard  9248:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9249:     }
1.169     brouard  9250:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9251:       month=99;
                   9252:       year=9999;
                   9253:     }else{
1.141     brouard  9254:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9255:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9256:       return 1;
1.136     brouard  9257:     }
                   9258:     andc[i]=(double) year; 
                   9259:     moisdc[i]=(double) month; 
                   9260:     strcpy(line,stra);
                   9261:     
1.223     brouard  9262:     /* Date of birth */
1.136     brouard  9263:     cutv(stra, strb,line,' '); 
1.169     brouard  9264:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9265:     }
1.169     brouard  9266:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9267:       month=99;
                   9268:       year=9999;
                   9269:     }else{
1.141     brouard  9270:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9271:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9272:       return 1;
1.136     brouard  9273:     }
                   9274:     if (year==9999) {
1.141     brouard  9275:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9276:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9277:       return 1;
                   9278:       
1.136     brouard  9279:     }
                   9280:     annais[i]=(double)(year);
                   9281:     moisnais[i]=(double)(month); 
                   9282:     strcpy(line,stra);
1.225     brouard  9283:     
1.223     brouard  9284:     /* Sample weight */
1.136     brouard  9285:     cutv(stra, strb,line,' '); 
                   9286:     errno=0;
                   9287:     dval=strtod(strb,&endptr); 
                   9288:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9289:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9290:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9291:       fflush(ficlog);
                   9292:       return 1;
                   9293:     }
                   9294:     weight[i]=dval; 
                   9295:     strcpy(line,stra);
1.225     brouard  9296:     
1.223     brouard  9297:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9298:       cutv(stra, strb, line, ' '); 
                   9299:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9300:        lval=-1;
1.223     brouard  9301:       }else{
1.225     brouard  9302:        errno=0;
                   9303:        /* what_kind_of_number(strb); */
                   9304:        dval=strtod(strb,&endptr);
                   9305:        /* if(strb != endptr && *endptr == '\0') */
                   9306:        /*   dval=dlval; */
                   9307:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9308:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9309:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9310:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9311:          return 1;
                   9312:        }
                   9313:        coqvar[iv][i]=dval; 
1.226     brouard  9314:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9315:       }
                   9316:       strcpy(line,stra);
                   9317:     }/* end loop nqv */
1.136     brouard  9318:     
1.223     brouard  9319:     /* Covariate values */
1.136     brouard  9320:     for (j=ncovcol;j>=1;j--){
                   9321:       cutv(stra, strb,line,' '); 
1.223     brouard  9322:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9323:        lval=-1;
1.136     brouard  9324:       }else{
1.225     brouard  9325:        errno=0;
                   9326:        lval=strtol(strb,&endptr,10); 
                   9327:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9328:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9329:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9330:          return 1;
                   9331:        }
1.136     brouard  9332:       }
                   9333:       if(lval <-1 || lval >1){
1.225     brouard  9334:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9335:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9336:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9337:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9338:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9339:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9340:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9341:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9342:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9343:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9344:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9345:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9346:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9347:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9348:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9349:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9350:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9351:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9352:        return 1;
1.136     brouard  9353:       }
                   9354:       covar[j][i]=(double)(lval);
                   9355:       strcpy(line,stra);
                   9356:     }  
                   9357:     lstra=strlen(stra);
1.225     brouard  9358:     
1.136     brouard  9359:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9360:       stratrunc = &(stra[lstra-9]);
                   9361:       num[i]=atol(stratrunc);
                   9362:     }
                   9363:     else
                   9364:       num[i]=atol(stra);
                   9365:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9366:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9367:     
                   9368:     i=i+1;
                   9369:   } /* End loop reading  data */
1.225     brouard  9370:   
1.136     brouard  9371:   *imax=i-1; /* Number of individuals */
                   9372:   fclose(fic);
1.225     brouard  9373:   
1.136     brouard  9374:   return (0);
1.164     brouard  9375:   /* endread: */
1.225     brouard  9376:   printf("Exiting readdata: ");
                   9377:   fclose(fic);
                   9378:   return (1);
1.223     brouard  9379: }
1.126     brouard  9380: 
1.234     brouard  9381: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9382:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9383:   while (*p2 == ' ')
1.234     brouard  9384:     p2++; 
                   9385:   /* while ((*p1++ = *p2++) !=0) */
                   9386:   /*   ; */
                   9387:   /* do */
                   9388:   /*   while (*p2 == ' ') */
                   9389:   /*     p2++; */
                   9390:   /* while (*p1++ == *p2++); */
                   9391:   *stri=p2; 
1.145     brouard  9392: }
                   9393: 
1.235     brouard  9394: int decoderesult ( char resultline[], int nres)
1.230     brouard  9395: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9396: {
1.235     brouard  9397:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9398:   char resultsav[MAXLINE];
1.234     brouard  9399:   int resultmodel[MAXLINE];
                   9400:   int modelresult[MAXLINE];
1.230     brouard  9401:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9402: 
1.234     brouard  9403:   removefirstspace(&resultline);
1.233     brouard  9404:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9405: 
                   9406:   if (strstr(resultline,"v") !=0){
                   9407:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9408:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9409:     return 1;
                   9410:   }
                   9411:   trimbb(resultsav, resultline);
                   9412:   if (strlen(resultsav) >1){
                   9413:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9414:   }
1.253     brouard  9415:   if(j == 0){ /* Resultline but no = */
                   9416:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9417:     return (0);
                   9418:   }
                   9419:     
1.234     brouard  9420:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9421:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9422:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9423:   }
                   9424:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9425:     if(nbocc(resultsav,'=') >1){
                   9426:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9427:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9428:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9429:     }else
                   9430:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9431:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9432:     
1.230     brouard  9433:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9434:     Tvarsel[k]=atoi(strc);
                   9435:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9436:     /* cptcovsel++;     */
                   9437:     if (nbocc(stra,'=') >0)
                   9438:       strcpy(resultsav,stra); /* and analyzes it */
                   9439:   }
1.235     brouard  9440:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9441:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9442:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9443:       match=0;
1.236     brouard  9444:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9445:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9446:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9447:          match=1;
                   9448:          break;
                   9449:        }
                   9450:       }
                   9451:       if(match == 0){
                   9452:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9453:       }
                   9454:     }
                   9455:   }
1.235     brouard  9456:   /* Checking for missing or useless values in comparison of current model needs */
                   9457:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9458:     match=0;
1.235     brouard  9459:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9460:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9461:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9462:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9463:          ++match;
                   9464:        }
                   9465:       }
                   9466:     }
                   9467:     if(match == 0){
                   9468:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9469:     }else if(match > 1){
                   9470:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9471:     }
                   9472:   }
1.235     brouard  9473:       
1.234     brouard  9474:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9475:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9476:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9477:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9478:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9479:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9480:   /*    1 0 0 0 */
                   9481:   /*    2 1 0 0 */
                   9482:   /*    3 0 1 0 */ 
                   9483:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9484:   /*    5 0 0 1 */
                   9485:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9486:   /*    7 0 1 1 */
                   9487:   /*    8 1 1 1 */
1.237     brouard  9488:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9489:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9490:   /* V5*age V5 known which value for nres?  */
                   9491:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9492:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9493:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9494:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9495:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9496:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9497:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9498:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9499:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9500:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9501:       k4++;;
                   9502:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9503:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9504:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9505:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9506:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9507:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9508:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9509:       k4q++;;
                   9510:     }
                   9511:   }
1.234     brouard  9512:   
1.235     brouard  9513:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9514:   return (0);
                   9515: }
1.235     brouard  9516: 
1.230     brouard  9517: int decodemodel( char model[], int lastobs)
                   9518:  /**< This routine decodes the model and returns:
1.224     brouard  9519:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9520:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9521:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9522:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9523:        * - cptcovage number of covariates with age*products =2
                   9524:        * - cptcovs number of simple covariates
                   9525:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9526:        *     which is a new column after the 9 (ncovcol) variables. 
                   9527:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9528:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9529:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9530:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9531:        */
1.136     brouard  9532: {
1.238     brouard  9533:   int i, j, k, ks, v;
1.227     brouard  9534:   int  j1, k1, k2, k3, k4;
1.136     brouard  9535:   char modelsav[80];
1.145     brouard  9536:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9537:   char *strpt;
1.136     brouard  9538: 
1.145     brouard  9539:   /*removespace(model);*/
1.136     brouard  9540:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9541:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9542:     if (strstr(model,"AGE") !=0){
1.192     brouard  9543:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9544:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9545:       return 1;
                   9546:     }
1.141     brouard  9547:     if (strstr(model,"v") !=0){
                   9548:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9549:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9550:       return 1;
                   9551:     }
1.187     brouard  9552:     strcpy(modelsav,model); 
                   9553:     if ((strpt=strstr(model,"age*age")) !=0){
                   9554:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9555:       if(strpt != model){
1.234     brouard  9556:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9557:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9558:  corresponding column of parameters.\n",model);
1.234     brouard  9559:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9560:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9561:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9562:        return 1;
1.225     brouard  9563:       }
1.187     brouard  9564:       nagesqr=1;
                   9565:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9566:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9567:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9568:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9569:       else 
1.234     brouard  9570:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9571:     }else
                   9572:       nagesqr=0;
                   9573:     if (strlen(modelsav) >1){
                   9574:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9575:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9576:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9577:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9578:                     * cst, age and age*age 
                   9579:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9580:       /* including age products which are counted in cptcovage.
                   9581:        * but the covariates which are products must be treated 
                   9582:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9583:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9584:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9585:       
                   9586:       
1.187     brouard  9587:       /*   Design
                   9588:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9589:        *  <          ncovcol=8                >
                   9590:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9591:        *   k=  1    2      3       4     5       6      7        8
                   9592:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9593:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9594:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9595:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9596:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9597:        *  Tage[++cptcovage]=k
                   9598:        *       if products, new covar are created after ncovcol with k1
                   9599:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9600:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9601:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9602:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9603:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9604:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9605:        *  <          ncovcol=8                >
                   9606:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9607:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9608:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9609:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9610:        * p Tprod[1]@2={                         6, 5}
                   9611:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9612:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9613:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9614:        *How to reorganize?
                   9615:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9616:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9617:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9618:        * Struct []
                   9619:        */
1.225     brouard  9620:       
1.187     brouard  9621:       /* This loop fills the array Tvar from the string 'model'.*/
                   9622:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9623:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9624:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9625:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9626:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9627:       /*       k=1 Tvar[1]=2 (from V2) */
                   9628:       /*       k=5 Tvar[5] */
                   9629:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9630:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9631:       /*       } */
1.198     brouard  9632:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9633:       /*
                   9634:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9635:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9636:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9637:       }
1.187     brouard  9638:       cptcovage=0;
                   9639:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9640:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9641:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9642:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9643:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9644:        /*scanf("%d",i);*/
                   9645:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9646:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9647:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9648:            /* covar is not filled and then is empty */
                   9649:            cptcovprod--;
                   9650:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9651:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9652:            Typevar[k]=1;  /* 1 for age product */
                   9653:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9654:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9655:            /*printf("stre=%s ", stre);*/
                   9656:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9657:            cptcovprod--;
                   9658:            cutl(stre,strb,strc,'V');
                   9659:            Tvar[k]=atoi(stre);
                   9660:            Typevar[k]=1;  /* 1 for age product */
                   9661:            cptcovage++;
                   9662:            Tage[cptcovage]=k;
                   9663:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9664:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9665:            cptcovn++;
                   9666:            cptcovprodnoage++;k1++;
                   9667:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9668:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9669:                                                because this model-covariate is a construction we invent a new column
                   9670:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9671:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9672:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9673:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9674:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9675:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9676:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9677:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9678:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9679:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9680:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9681:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9682:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9683:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9684:            for (i=1; i<=lastobs;i++){
                   9685:              /* Computes the new covariate which is a product of
                   9686:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9687:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9688:            }
                   9689:          } /* End age is not in the model */
                   9690:        } /* End if model includes a product */
                   9691:        else { /* no more sum */
                   9692:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9693:          /*  scanf("%d",i);*/
                   9694:          cutl(strd,strc,strb,'V');
                   9695:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9696:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9697:          Tvar[k]=atoi(strd);
                   9698:          Typevar[k]=0;  /* 0 for simple covariates */
                   9699:        }
                   9700:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9701:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9702:                                  scanf("%d",i);*/
1.187     brouard  9703:       } /* end of loop + on total covariates */
                   9704:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9705:   } /* end if strlen(model == 0) */
1.136     brouard  9706:   
                   9707:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9708:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9709:   
1.136     brouard  9710:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9711:      printf("cptcovprod=%d ", cptcovprod);
                   9712:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9713:      scanf("%d ",i);*/
                   9714: 
                   9715: 
1.230     brouard  9716: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9717:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9718: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9719:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9720:    k =           1    2   3     4       5       6      7      8        9
                   9721:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9722:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9723:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9724:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9725:          Tmodelind[combination of covar]=k;
1.225     brouard  9726: */  
                   9727: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9728:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9729:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9730:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9731:   printf("Model=%s\n\
                   9732: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9733: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9734: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9735:   fprintf(ficlog,"Model=%s\n\
                   9736: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9737: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9738: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9739:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9740:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9741:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9742:       Fixed[k]= 0;
                   9743:       Dummy[k]= 0;
1.225     brouard  9744:       ncoveff++;
1.232     brouard  9745:       ncovf++;
1.234     brouard  9746:       nsd++;
                   9747:       modell[k].maintype= FTYPE;
                   9748:       TvarsD[nsd]=Tvar[k];
                   9749:       TvarsDind[nsd]=k;
                   9750:       TvarF[ncovf]=Tvar[k];
                   9751:       TvarFind[ncovf]=k;
                   9752:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9753:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9754:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9755:       Fixed[k]= 0;
                   9756:       Dummy[k]= 0;
                   9757:       ncoveff++;
                   9758:       ncovf++;
                   9759:       modell[k].maintype= FTYPE;
                   9760:       TvarF[ncovf]=Tvar[k];
                   9761:       TvarFind[ncovf]=k;
1.230     brouard  9762:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9763:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9764:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9765:       Fixed[k]= 0;
                   9766:       Dummy[k]= 1;
1.230     brouard  9767:       nqfveff++;
1.234     brouard  9768:       modell[k].maintype= FTYPE;
                   9769:       modell[k].subtype= FQ;
                   9770:       nsq++;
                   9771:       TvarsQ[nsq]=Tvar[k];
                   9772:       TvarsQind[nsq]=k;
1.232     brouard  9773:       ncovf++;
1.234     brouard  9774:       TvarF[ncovf]=Tvar[k];
                   9775:       TvarFind[ncovf]=k;
1.231     brouard  9776:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9777:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9778:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9779:       Fixed[k]= 1;
                   9780:       Dummy[k]= 0;
1.225     brouard  9781:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9782:       modell[k].maintype= VTYPE;
                   9783:       modell[k].subtype= VD;
                   9784:       nsd++;
                   9785:       TvarsD[nsd]=Tvar[k];
                   9786:       TvarsDind[nsd]=k;
                   9787:       ncovv++; /* Only simple time varying variables */
                   9788:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9789:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9790:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9791:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9792:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9793:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9794:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9795:       Fixed[k]= 1;
                   9796:       Dummy[k]= 1;
                   9797:       nqtveff++;
                   9798:       modell[k].maintype= VTYPE;
                   9799:       modell[k].subtype= VQ;
                   9800:       ncovv++; /* Only simple time varying variables */
                   9801:       nsq++;
                   9802:       TvarsQ[nsq]=Tvar[k];
                   9803:       TvarsQind[nsq]=k;
                   9804:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9805:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9806:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9807:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9808:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9809:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9810:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9811:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9812:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9813:       ncova++;
                   9814:       TvarA[ncova]=Tvar[k];
                   9815:       TvarAind[ncova]=k;
1.231     brouard  9816:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9817:        Fixed[k]= 2;
                   9818:        Dummy[k]= 2;
                   9819:        modell[k].maintype= ATYPE;
                   9820:        modell[k].subtype= APFD;
                   9821:        /* ncoveff++; */
1.227     brouard  9822:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9823:        Fixed[k]= 2;
                   9824:        Dummy[k]= 3;
                   9825:        modell[k].maintype= ATYPE;
                   9826:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9827:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9828:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9829:        Fixed[k]= 3;
                   9830:        Dummy[k]= 2;
                   9831:        modell[k].maintype= ATYPE;
                   9832:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9833:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9834:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9835:        Fixed[k]= 3;
                   9836:        Dummy[k]= 3;
                   9837:        modell[k].maintype= ATYPE;
                   9838:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9839:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9840:       }
                   9841:     }else if (Typevar[k] == 2) {  /* product without age */
                   9842:       k1=Tposprod[k];
                   9843:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9844:        if(Tvard[k1][2] <=ncovcol){
                   9845:          Fixed[k]= 1;
                   9846:          Dummy[k]= 0;
                   9847:          modell[k].maintype= FTYPE;
                   9848:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9849:          ncovf++; /* Fixed variables without age */
                   9850:          TvarF[ncovf]=Tvar[k];
                   9851:          TvarFind[ncovf]=k;
                   9852:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9853:          Fixed[k]= 0;  /* or 2 ?*/
                   9854:          Dummy[k]= 1;
                   9855:          modell[k].maintype= FTYPE;
                   9856:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9857:          ncovf++; /* Varying variables without age */
                   9858:          TvarF[ncovf]=Tvar[k];
                   9859:          TvarFind[ncovf]=k;
                   9860:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9861:          Fixed[k]= 1;
                   9862:          Dummy[k]= 0;
                   9863:          modell[k].maintype= VTYPE;
                   9864:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9865:          ncovv++; /* Varying variables without age */
                   9866:          TvarV[ncovv]=Tvar[k];
                   9867:          TvarVind[ncovv]=k;
                   9868:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9869:          Fixed[k]= 1;
                   9870:          Dummy[k]= 1;
                   9871:          modell[k].maintype= VTYPE;
                   9872:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9873:          ncovv++; /* Varying variables without age */
                   9874:          TvarV[ncovv]=Tvar[k];
                   9875:          TvarVind[ncovv]=k;
                   9876:        }
1.227     brouard  9877:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9878:        if(Tvard[k1][2] <=ncovcol){
                   9879:          Fixed[k]= 0;  /* or 2 ?*/
                   9880:          Dummy[k]= 1;
                   9881:          modell[k].maintype= FTYPE;
                   9882:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9883:          ncovf++; /* Fixed variables without age */
                   9884:          TvarF[ncovf]=Tvar[k];
                   9885:          TvarFind[ncovf]=k;
                   9886:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9887:          Fixed[k]= 1;
                   9888:          Dummy[k]= 1;
                   9889:          modell[k].maintype= VTYPE;
                   9890:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9891:          ncovv++; /* Varying variables without age */
                   9892:          TvarV[ncovv]=Tvar[k];
                   9893:          TvarVind[ncovv]=k;
                   9894:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9895:          Fixed[k]= 1;
                   9896:          Dummy[k]= 1;
                   9897:          modell[k].maintype= VTYPE;
                   9898:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9899:          ncovv++; /* Varying variables without age */
                   9900:          TvarV[ncovv]=Tvar[k];
                   9901:          TvarVind[ncovv]=k;
                   9902:          ncovv++; /* Varying variables without age */
                   9903:          TvarV[ncovv]=Tvar[k];
                   9904:          TvarVind[ncovv]=k;
                   9905:        }
1.227     brouard  9906:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9907:        if(Tvard[k1][2] <=ncovcol){
                   9908:          Fixed[k]= 1;
                   9909:          Dummy[k]= 1;
                   9910:          modell[k].maintype= VTYPE;
                   9911:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9912:          ncovv++; /* Varying variables without age */
                   9913:          TvarV[ncovv]=Tvar[k];
                   9914:          TvarVind[ncovv]=k;
                   9915:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9916:          Fixed[k]= 1;
                   9917:          Dummy[k]= 1;
                   9918:          modell[k].maintype= VTYPE;
                   9919:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9920:          ncovv++; /* Varying variables without age */
                   9921:          TvarV[ncovv]=Tvar[k];
                   9922:          TvarVind[ncovv]=k;
                   9923:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9924:          Fixed[k]= 1;
                   9925:          Dummy[k]= 0;
                   9926:          modell[k].maintype= VTYPE;
                   9927:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9928:          ncovv++; /* Varying variables without age */
                   9929:          TvarV[ncovv]=Tvar[k];
                   9930:          TvarVind[ncovv]=k;
                   9931:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9932:          Fixed[k]= 1;
                   9933:          Dummy[k]= 1;
                   9934:          modell[k].maintype= VTYPE;
                   9935:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9936:          ncovv++; /* Varying variables without age */
                   9937:          TvarV[ncovv]=Tvar[k];
                   9938:          TvarVind[ncovv]=k;
                   9939:        }
1.227     brouard  9940:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9941:        if(Tvard[k1][2] <=ncovcol){
                   9942:          Fixed[k]= 1;
                   9943:          Dummy[k]= 1;
                   9944:          modell[k].maintype= VTYPE;
                   9945:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9946:          ncovv++; /* Varying variables without age */
                   9947:          TvarV[ncovv]=Tvar[k];
                   9948:          TvarVind[ncovv]=k;
                   9949:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9950:          Fixed[k]= 1;
                   9951:          Dummy[k]= 1;
                   9952:          modell[k].maintype= VTYPE;
                   9953:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9954:          ncovv++; /* Varying variables without age */
                   9955:          TvarV[ncovv]=Tvar[k];
                   9956:          TvarVind[ncovv]=k;
                   9957:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9958:          Fixed[k]= 1;
                   9959:          Dummy[k]= 1;
                   9960:          modell[k].maintype= VTYPE;
                   9961:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9962:          ncovv++; /* Varying variables without age */
                   9963:          TvarV[ncovv]=Tvar[k];
                   9964:          TvarVind[ncovv]=k;
                   9965:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9966:          Fixed[k]= 1;
                   9967:          Dummy[k]= 1;
                   9968:          modell[k].maintype= VTYPE;
                   9969:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9970:          ncovv++; /* Varying variables without age */
                   9971:          TvarV[ncovv]=Tvar[k];
                   9972:          TvarVind[ncovv]=k;
                   9973:        }
1.227     brouard  9974:       }else{
1.240     brouard  9975:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9976:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9977:       } /*end k1*/
1.225     brouard  9978:     }else{
1.226     brouard  9979:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   9980:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  9981:     }
1.227     brouard  9982:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  9983:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  9984:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   9985:   }
                   9986:   /* Searching for doublons in the model */
                   9987:   for(k1=1; k1<= cptcovt;k1++){
                   9988:     for(k2=1; k2 <k1;k2++){
1.285     brouard  9989:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   9990:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  9991:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   9992:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  9993:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   9994:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  9995:            return(1);
                   9996:          }
                   9997:        }else if (Typevar[k1] ==2){
                   9998:          k3=Tposprod[k1];
                   9999:          k4=Tposprod[k2];
                   10000:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10001:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10002:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10003:            return(1);
                   10004:          }
                   10005:        }
1.227     brouard  10006:       }
                   10007:     }
1.225     brouard  10008:   }
                   10009:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10010:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10011:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10012:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10013:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10014:   /*endread:*/
1.225     brouard  10015:   printf("Exiting decodemodel: ");
                   10016:   return (1);
1.136     brouard  10017: }
                   10018: 
1.169     brouard  10019: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10020: {/* Check ages at death */
1.136     brouard  10021:   int i, m;
1.218     brouard  10022:   int firstone=0;
                   10023:   
1.136     brouard  10024:   for (i=1; i<=imx; i++) {
                   10025:     for(m=2; (m<= maxwav); m++) {
                   10026:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10027:        anint[m][i]=9999;
1.216     brouard  10028:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10029:          s[m][i]=-1;
1.136     brouard  10030:       }
                   10031:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10032:        *nberr = *nberr + 1;
1.218     brouard  10033:        if(firstone == 0){
                   10034:          firstone=1;
1.260     brouard  10035:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10036:        }
1.262     brouard  10037:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10038:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10039:       }
                   10040:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10041:        (*nberr)++;
1.259     brouard  10042:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10043:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10044:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10045:       }
                   10046:     }
                   10047:   }
                   10048: 
                   10049:   for (i=1; i<=imx; i++)  {
                   10050:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10051:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10052:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10053:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10054:          if(agedc[i]>0){
                   10055:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10056:              agev[m][i]=agedc[i];
1.214     brouard  10057:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10058:            }else {
1.136     brouard  10059:              if ((int)andc[i]!=9999){
                   10060:                nbwarn++;
                   10061:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10062:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10063:                agev[m][i]=-1;
                   10064:              }
                   10065:            }
1.169     brouard  10066:          } /* agedc > 0 */
1.214     brouard  10067:        } /* end if */
1.136     brouard  10068:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10069:                                 years but with the precision of a month */
                   10070:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10071:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10072:            agev[m][i]=1;
                   10073:          else if(agev[m][i] < *agemin){ 
                   10074:            *agemin=agev[m][i];
                   10075:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10076:          }
                   10077:          else if(agev[m][i] >*agemax){
                   10078:            *agemax=agev[m][i];
1.156     brouard  10079:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10080:          }
                   10081:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10082:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10083:        } /* en if 9*/
1.136     brouard  10084:        else { /* =9 */
1.214     brouard  10085:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10086:          agev[m][i]=1;
                   10087:          s[m][i]=-1;
                   10088:        }
                   10089:       }
1.214     brouard  10090:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10091:        agev[m][i]=1;
1.214     brouard  10092:       else{
                   10093:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10094:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10095:        agev[m][i]=0;
                   10096:       }
                   10097:     } /* End for lastpass */
                   10098:   }
1.136     brouard  10099:     
                   10100:   for (i=1; i<=imx; i++)  {
                   10101:     for(m=firstpass; (m<=lastpass); m++){
                   10102:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10103:        (*nberr)++;
1.136     brouard  10104:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10105:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10106:        return 1;
                   10107:       }
                   10108:     }
                   10109:   }
                   10110: 
                   10111:   /*for (i=1; i<=imx; i++){
                   10112:   for (m=firstpass; (m<lastpass); m++){
                   10113:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10114: }
                   10115: 
                   10116: }*/
                   10117: 
                   10118: 
1.139     brouard  10119:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10120:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10121: 
                   10122:   return (0);
1.164     brouard  10123:  /* endread:*/
1.136     brouard  10124:     printf("Exiting calandcheckages: ");
                   10125:     return (1);
                   10126: }
                   10127: 
1.172     brouard  10128: #if defined(_MSC_VER)
                   10129: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10130: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10131: //#include "stdafx.h"
                   10132: //#include <stdio.h>
                   10133: //#include <tchar.h>
                   10134: //#include <windows.h>
                   10135: //#include <iostream>
                   10136: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10137: 
                   10138: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10139: 
                   10140: BOOL IsWow64()
                   10141: {
                   10142:        BOOL bIsWow64 = FALSE;
                   10143: 
                   10144:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10145:        //  (HANDLE, PBOOL);
                   10146: 
                   10147:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10148: 
                   10149:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10150:        const char funcName[] = "IsWow64Process";
                   10151:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10152:                GetProcAddress(module, funcName);
                   10153: 
                   10154:        if (NULL != fnIsWow64Process)
                   10155:        {
                   10156:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10157:                        &bIsWow64))
                   10158:                        //throw std::exception("Unknown error");
                   10159:                        printf("Unknown error\n");
                   10160:        }
                   10161:        return bIsWow64 != FALSE;
                   10162: }
                   10163: #endif
1.177     brouard  10164: 
1.191     brouard  10165: void syscompilerinfo(int logged)
1.167     brouard  10166:  {
                   10167:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10168:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10169:    /* /GS /W3 /Gy
                   10170:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10171:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10172:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10173:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10174:    */ 
                   10175:    /* 64 bits */
1.185     brouard  10176:    /*
                   10177:      /GS /W3 /Gy
                   10178:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10179:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10180:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10181:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10182:    /* Optimization are useless and O3 is slower than O2 */
                   10183:    /*
                   10184:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10185:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10186:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10187:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10188:    */
1.186     brouard  10189:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10190:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10191:       /PDB:"visual studio
                   10192:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10193:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10194:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10195:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10196:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10197:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10198:       uiAccess='false'"
                   10199:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10200:       /NOLOGO /TLBID:1
                   10201:    */
1.177     brouard  10202: #if defined __INTEL_COMPILER
1.178     brouard  10203: #if defined(__GNUC__)
                   10204:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10205: #endif
1.177     brouard  10206: #elif defined(__GNUC__) 
1.179     brouard  10207: #ifndef  __APPLE__
1.174     brouard  10208: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10209: #endif
1.177     brouard  10210:    struct utsname sysInfo;
1.178     brouard  10211:    int cross = CROSS;
                   10212:    if (cross){
                   10213:           printf("Cross-");
1.191     brouard  10214:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10215:    }
1.174     brouard  10216: #endif
                   10217: 
1.171     brouard  10218: #include <stdint.h>
1.178     brouard  10219: 
1.191     brouard  10220:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10221: #if defined(__clang__)
1.191     brouard  10222:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10223: #endif
                   10224: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10225:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10226: #endif
                   10227: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10228:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10229: #endif
                   10230: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10231:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10232: #endif
                   10233: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10234:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10235: #endif
                   10236: #if defined(_MSC_VER)
1.191     brouard  10237:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10238: #endif
                   10239: #if defined(__PGI)
1.191     brouard  10240:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10241: #endif
                   10242: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10243:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10244: #endif
1.191     brouard  10245:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10246:    
1.167     brouard  10247: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10248: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10249:     // Windows (x64 and x86)
1.191     brouard  10250:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10251: #elif __unix__ // all unices, not all compilers
                   10252:     // Unix
1.191     brouard  10253:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10254: #elif __linux__
                   10255:     // linux
1.191     brouard  10256:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10257: #elif __APPLE__
1.174     brouard  10258:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10259:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10260: #endif
                   10261: 
                   10262: /*  __MINGW32__          */
                   10263: /*  __CYGWIN__  */
                   10264: /* __MINGW64__  */
                   10265: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10266: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10267: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10268: /* _WIN64  // Defined for applications for Win64. */
                   10269: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10270: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10271: 
1.167     brouard  10272: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10273:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10274: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10275:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10276: #else
1.191     brouard  10277:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10278: #endif
                   10279: 
1.169     brouard  10280: #if defined(__GNUC__)
                   10281: # if defined(__GNUC_PATCHLEVEL__)
                   10282: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10283:                             + __GNUC_MINOR__ * 100 \
                   10284:                             + __GNUC_PATCHLEVEL__)
                   10285: # else
                   10286: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10287:                             + __GNUC_MINOR__ * 100)
                   10288: # endif
1.174     brouard  10289:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10290:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10291: 
                   10292:    if (uname(&sysInfo) != -1) {
                   10293:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10294:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10295:    }
                   10296:    else
                   10297:       perror("uname() error");
1.179     brouard  10298:    //#ifndef __INTEL_COMPILER 
                   10299: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10300:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10301:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10302: #endif
1.169     brouard  10303: #endif
1.172     brouard  10304: 
1.286   ! brouard  10305:    //   void main ()
1.172     brouard  10306:    //   {
1.169     brouard  10307: #if defined(_MSC_VER)
1.174     brouard  10308:    if (IsWow64()){
1.191     brouard  10309:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10310:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10311:    }
                   10312:    else{
1.191     brouard  10313:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10314:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10315:    }
1.172     brouard  10316:    //     printf("\nPress Enter to continue...");
                   10317:    //     getchar();
                   10318:    //   }
                   10319: 
1.169     brouard  10320: #endif
                   10321:    
1.167     brouard  10322: 
1.219     brouard  10323: }
1.136     brouard  10324: 
1.219     brouard  10325: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.180     brouard  10326:   /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.235     brouard  10327:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10328:   /* double ftolpl = 1.e-10; */
1.180     brouard  10329:   double age, agebase, agelim;
1.203     brouard  10330:   double tot;
1.180     brouard  10331: 
1.202     brouard  10332:   strcpy(filerespl,"PL_");
                   10333:   strcat(filerespl,fileresu);
                   10334:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
                   10335:     printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10336:     fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10337:   }
1.227     brouard  10338:   printf("\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
                   10339:   fprintf(ficlog,"\nComputing period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10340:   pstamp(ficrespl);
1.203     brouard  10341:   fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10342:   fprintf(ficrespl,"#Age ");
                   10343:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10344:   fprintf(ficrespl,"\n");
1.180     brouard  10345:   
1.219     brouard  10346:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10347: 
1.219     brouard  10348:   agebase=ageminpar;
                   10349:   agelim=agemaxpar;
1.180     brouard  10350: 
1.227     brouard  10351:   /* i1=pow(2,ncoveff); */
1.234     brouard  10352:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10353:   if (cptcovn < 1){i1=1;}
1.180     brouard  10354: 
1.238     brouard  10355:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10356:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10357:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10358:        continue;
1.235     brouard  10359: 
1.238     brouard  10360:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10361:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10362:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10363:       /* k=k+1; */
                   10364:       /* to clean */
                   10365:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10366:       fprintf(ficrespl,"#******");
                   10367:       printf("#******");
                   10368:       fprintf(ficlog,"#******");
                   10369:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10370:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10371:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10372:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10373:       }
                   10374:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10375:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10376:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10377:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10378:       }
                   10379:       fprintf(ficrespl,"******\n");
                   10380:       printf("******\n");
                   10381:       fprintf(ficlog,"******\n");
                   10382:       if(invalidvarcomb[k]){
                   10383:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10384:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10385:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10386:        continue;
                   10387:       }
1.219     brouard  10388: 
1.238     brouard  10389:       fprintf(ficrespl,"#Age ");
                   10390:       for(j=1;j<=cptcoveff;j++) {
                   10391:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10392:       }
                   10393:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10394:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10395:     
1.238     brouard  10396:       for (age=agebase; age<=agelim; age++){
                   10397:        /* for (age=agebase; age<=agebase; age++){ */
                   10398:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10399:        fprintf(ficrespl,"%.0f ",age );
                   10400:        for(j=1;j<=cptcoveff;j++)
                   10401:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10402:        tot=0.;
                   10403:        for(i=1; i<=nlstate;i++){
                   10404:          tot +=  prlim[i][i];
                   10405:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10406:        }
                   10407:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10408:       } /* Age */
                   10409:       /* was end of cptcod */
                   10410:     } /* cptcov */
                   10411:   } /* nres */
1.219     brouard  10412:   return 0;
1.180     brouard  10413: }
                   10414: 
1.218     brouard  10415: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
                   10416:        /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   10417:        
                   10418:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10419:    * at any age between ageminpar and agemaxpar
                   10420:         */
1.235     brouard  10421:   int i, j, k, i1, nres=0 ;
1.217     brouard  10422:   /* double ftolpl = 1.e-10; */
                   10423:   double age, agebase, agelim;
                   10424:   double tot;
1.218     brouard  10425:   /* double ***mobaverage; */
                   10426:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10427: 
                   10428:   strcpy(fileresplb,"PLB_");
                   10429:   strcat(fileresplb,fileresu);
                   10430:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
                   10431:     printf("Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10432:     fprintf(ficlog,"Problem with period (stable) back prevalence resultfile: %s\n", fileresplb);return 1;
                   10433:   }
                   10434:   printf("Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10435:   fprintf(ficlog,"Computing period (stable) back prevalence: result on file '%s' \n", fileresplb);
                   10436:   pstamp(ficresplb);
                   10437:   fprintf(ficresplb,"# Period (stable) back prevalence. Precision given by ftolpl=%g \n", ftolpl);
                   10438:   fprintf(ficresplb,"#Age ");
                   10439:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10440:   fprintf(ficresplb,"\n");
                   10441:   
1.218     brouard  10442:   
                   10443:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10444:   
                   10445:   agebase=ageminpar;
                   10446:   agelim=agemaxpar;
                   10447:   
                   10448:   
1.227     brouard  10449:   i1=pow(2,cptcoveff);
1.218     brouard  10450:   if (cptcovn < 1){i1=1;}
1.227     brouard  10451:   
1.238     brouard  10452:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10453:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10454:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10455:        continue;
                   10456:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10457:       fprintf(ficresplb,"#******");
                   10458:       printf("#******");
                   10459:       fprintf(ficlog,"#******");
                   10460:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10461:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10462:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10463:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10464:       }
                   10465:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10466:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10467:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10468:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10469:       }
                   10470:       fprintf(ficresplb,"******\n");
                   10471:       printf("******\n");
                   10472:       fprintf(ficlog,"******\n");
                   10473:       if(invalidvarcomb[k]){
                   10474:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10475:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10476:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10477:        continue;
                   10478:       }
1.218     brouard  10479:     
1.238     brouard  10480:       fprintf(ficresplb,"#Age ");
                   10481:       for(j=1;j<=cptcoveff;j++) {
                   10482:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10483:       }
                   10484:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10485:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10486:     
                   10487:     
1.238     brouard  10488:       for (age=agebase; age<=agelim; age++){
                   10489:        /* for (age=agebase; age<=agebase; age++){ */
                   10490:        if(mobilavproj > 0){
                   10491:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10492:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10493:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10494:        }else if (mobilavproj == 0){
                   10495:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10496:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10497:          exit(1);
                   10498:        }else{
                   10499:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10500:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10501:          /* printf("TOTOT\n"); */
                   10502:           /* exit(1); */
1.238     brouard  10503:        }
                   10504:        fprintf(ficresplb,"%.0f ",age );
                   10505:        for(j=1;j<=cptcoveff;j++)
                   10506:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10507:        tot=0.;
                   10508:        for(i=1; i<=nlstate;i++){
                   10509:          tot +=  bprlim[i][i];
                   10510:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10511:        }
                   10512:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10513:       } /* Age */
                   10514:       /* was end of cptcod */
1.255     brouard  10515:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10516:     } /* end of any combination */
                   10517:   } /* end of nres */  
1.218     brouard  10518:   /* hBijx(p, bage, fage); */
                   10519:   /* fclose(ficrespijb); */
                   10520:   
                   10521:   return 0;
1.217     brouard  10522: }
1.218     brouard  10523:  
1.180     brouard  10524: int hPijx(double *p, int bage, int fage){
                   10525:     /*------------- h Pij x at various ages ------------*/
                   10526: 
                   10527:   int stepsize;
                   10528:   int agelim;
                   10529:   int hstepm;
                   10530:   int nhstepm;
1.235     brouard  10531:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10532: 
                   10533:   double agedeb;
                   10534:   double ***p3mat;
                   10535: 
1.201     brouard  10536:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10537:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10538:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10539:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10540:     }
                   10541:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10542:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10543:   
                   10544:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10545:     /*if (stepm<=24) stepsize=2;*/
                   10546: 
                   10547:     agelim=AGESUP;
                   10548:     hstepm=stepsize*YEARM; /* Every year of age */
                   10549:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10550:                
1.180     brouard  10551:     /* hstepm=1;   aff par mois*/
                   10552:     pstamp(ficrespij);
                   10553:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10554:     i1= pow(2,cptcoveff);
1.218     brouard  10555:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10556:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10557:                /*      k=k+1;  */
1.235     brouard  10558:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10559:     for(k=1; k<=i1;k++){
1.253     brouard  10560:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10561:        continue;
1.183     brouard  10562:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10563:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10564:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10565:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10566:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10567:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10568:       }
1.183     brouard  10569:       fprintf(ficrespij,"******\n");
                   10570:       
                   10571:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10572:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10573:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10574:        
                   10575:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10576:        
1.183     brouard  10577:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10578:        oldm=oldms;savm=savms;
1.235     brouard  10579:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10580:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10581:        for(i=1; i<=nlstate;i++)
                   10582:          for(j=1; j<=nlstate+ndeath;j++)
                   10583:            fprintf(ficrespij," %1d-%1d",i,j);
                   10584:        fprintf(ficrespij,"\n");
                   10585:        for (h=0; h<=nhstepm; h++){
                   10586:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10587:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10588:          for(i=1; i<=nlstate;i++)
                   10589:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10590:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10591:          fprintf(ficrespij,"\n");
                   10592:        }
1.183     brouard  10593:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10594:        fprintf(ficrespij,"\n");
                   10595:       }
1.180     brouard  10596:       /*}*/
                   10597:     }
1.218     brouard  10598:     return 0;
1.180     brouard  10599: }
1.218     brouard  10600:  
                   10601:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10602:     /*------------- h Bij x at various ages ------------*/
                   10603: 
                   10604:   int stepsize;
1.218     brouard  10605:   /* int agelim; */
                   10606:        int ageminl;
1.217     brouard  10607:   int hstepm;
                   10608:   int nhstepm;
1.238     brouard  10609:   int h, i, i1, j, k, nres;
1.218     brouard  10610:        
1.217     brouard  10611:   double agedeb;
                   10612:   double ***p3mat;
1.218     brouard  10613:        
                   10614:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10615:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10616:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10617:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10618:   }
                   10619:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10620:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10621:   
                   10622:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10623:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10624:   
1.218     brouard  10625:   /* agelim=AGESUP; */
                   10626:   ageminl=30;
                   10627:   hstepm=stepsize*YEARM; /* Every year of age */
                   10628:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10629:   
                   10630:   /* hstepm=1;   aff par mois*/
                   10631:   pstamp(ficrespijb);
1.255     brouard  10632:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10633:   i1= pow(2,cptcoveff);
1.218     brouard  10634:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10635:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10636:   /*   k=k+1;  */
1.238     brouard  10637:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10638:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10639:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10640:        continue;
                   10641:       fprintf(ficrespijb,"\n#****** ");
                   10642:       for(j=1;j<=cptcoveff;j++)
                   10643:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10644:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10645:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10646:       }
                   10647:       fprintf(ficrespijb,"******\n");
1.264     brouard  10648:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10649:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10650:        continue;
                   10651:       }
                   10652:       
                   10653:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10654:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10655:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10656:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10657:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10658:        
                   10659:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10660:        
1.266     brouard  10661:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10662:        /* and memory limitations if stepm is small */
                   10663: 
1.238     brouard  10664:        /* oldm=oldms;savm=savms; */
                   10665:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10666:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10667:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10668:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10669:        for(i=1; i<=nlstate;i++)
                   10670:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10671:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10672:        fprintf(ficrespijb,"\n");
1.238     brouard  10673:        for (h=0; h<=nhstepm; h++){
                   10674:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10675:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10676:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10677:          for(i=1; i<=nlstate;i++)
                   10678:            for(j=1; j<=nlstate+ndeath;j++)
                   10679:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10680:          fprintf(ficrespijb,"\n");
                   10681:        }
                   10682:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10683:        fprintf(ficrespijb,"\n");
                   10684:       } /* end age deb */
                   10685:     } /* end combination */
                   10686:   } /* end nres */
1.218     brouard  10687:   return 0;
                   10688:  } /*  hBijx */
1.217     brouard  10689: 
1.180     brouard  10690: 
1.136     brouard  10691: /***********************************************/
                   10692: /**************** Main Program *****************/
                   10693: /***********************************************/
                   10694: 
                   10695: int main(int argc, char *argv[])
                   10696: {
                   10697: #ifdef GSL
                   10698:   const gsl_multimin_fminimizer_type *T;
                   10699:   size_t iteri = 0, it;
                   10700:   int rval = GSL_CONTINUE;
                   10701:   int status = GSL_SUCCESS;
                   10702:   double ssval;
                   10703: #endif
                   10704:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10705:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10706:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10707:   int jj, ll, li, lj, lk;
1.136     brouard  10708:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10709:   int num_filled;
1.136     brouard  10710:   int itimes;
                   10711:   int NDIM=2;
                   10712:   int vpopbased=0;
1.235     brouard  10713:   int nres=0;
1.258     brouard  10714:   int endishere=0;
1.277     brouard  10715:   int noffset=0;
1.274     brouard  10716:   int ncurrv=0; /* Temporary variable */
                   10717:   
1.164     brouard  10718:   char ca[32], cb[32];
1.136     brouard  10719:   /*  FILE *fichtm; *//* Html File */
                   10720:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10721:   struct stat info;
1.191     brouard  10722:   double agedeb=0.;
1.194     brouard  10723: 
                   10724:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10725:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10726: 
1.165     brouard  10727:   double fret;
1.191     brouard  10728:   double dum=0.; /* Dummy variable */
1.136     brouard  10729:   double ***p3mat;
1.218     brouard  10730:   /* double ***mobaverage; */
1.164     brouard  10731: 
                   10732:   char line[MAXLINE];
1.197     brouard  10733:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10734: 
1.234     brouard  10735:   char  modeltemp[MAXLINE];
1.230     brouard  10736:   char resultline[MAXLINE];
                   10737:   
1.136     brouard  10738:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10739:   char *tok, *val; /* pathtot */
1.136     brouard  10740:   int firstobs=1, lastobs=10;
1.195     brouard  10741:   int c,  h , cpt, c2;
1.191     brouard  10742:   int jl=0;
                   10743:   int i1, j1, jk, stepsize=0;
1.194     brouard  10744:   int count=0;
                   10745: 
1.164     brouard  10746:   int *tab; 
1.136     brouard  10747:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10748:   int backcast=0;
1.136     brouard  10749:   int mobilav=0,popforecast=0;
1.191     brouard  10750:   int hstepm=0, nhstepm=0;
1.136     brouard  10751:   int agemortsup;
                   10752:   float  sumlpop=0.;
                   10753:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10754:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10755: 
1.191     brouard  10756:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10757:   double ftolpl=FTOL;
                   10758:   double **prlim;
1.217     brouard  10759:   double **bprlim;
1.136     brouard  10760:   double ***param; /* Matrix of parameters */
1.251     brouard  10761:   double ***paramstart; /* Matrix of starting parameter values */
                   10762:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10763:   double **matcov; /* Matrix of covariance */
1.203     brouard  10764:   double **hess; /* Hessian matrix */
1.136     brouard  10765:   double ***delti3; /* Scale */
                   10766:   double *delti; /* Scale */
                   10767:   double ***eij, ***vareij;
                   10768:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10769: 
1.136     brouard  10770:   double *epj, vepp;
1.164     brouard  10771: 
1.273     brouard  10772:   double dateprev1, dateprev2;
                   10773:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10774:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10775: 
1.136     brouard  10776:   double **ximort;
1.145     brouard  10777:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10778:   int *dcwave;
                   10779: 
1.164     brouard  10780:   char z[1]="c";
1.136     brouard  10781: 
                   10782:   /*char  *strt;*/
                   10783:   char strtend[80];
1.126     brouard  10784: 
1.164     brouard  10785: 
1.126     brouard  10786: /*   setlocale (LC_ALL, ""); */
                   10787: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10788: /*   textdomain (PACKAGE); */
                   10789: /*   setlocale (LC_CTYPE, ""); */
                   10790: /*   setlocale (LC_MESSAGES, ""); */
                   10791: 
                   10792:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10793:   rstart_time = time(NULL);  
                   10794:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10795:   start_time = *localtime(&rstart_time);
1.126     brouard  10796:   curr_time=start_time;
1.157     brouard  10797:   /*tml = *localtime(&start_time.tm_sec);*/
                   10798:   /* strcpy(strstart,asctime(&tml)); */
                   10799:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10800: 
                   10801: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10802: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10803: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10804: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10805: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10806: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10807: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10808: /*   strt=asctime(&tmg); */
                   10809: /*   printf("Time(after) =%s",strstart);  */
                   10810: /*  (void) time (&time_value);
                   10811: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10812: *  tm = *localtime(&time_value);
                   10813: *  strstart=asctime(&tm);
                   10814: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10815: */
                   10816: 
                   10817:   nberr=0; /* Number of errors and warnings */
                   10818:   nbwarn=0;
1.184     brouard  10819: #ifdef WIN32
                   10820:   _getcwd(pathcd, size);
                   10821: #else
1.126     brouard  10822:   getcwd(pathcd, size);
1.184     brouard  10823: #endif
1.191     brouard  10824:   syscompilerinfo(0);
1.196     brouard  10825:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10826:   if(argc <=1){
                   10827:     printf("\nEnter the parameter file name: ");
1.205     brouard  10828:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10829:       printf("ERROR Empty parameter file name\n");
                   10830:       goto end;
                   10831:     }
1.126     brouard  10832:     i=strlen(pathr);
                   10833:     if(pathr[i-1]=='\n')
                   10834:       pathr[i-1]='\0';
1.156     brouard  10835:     i=strlen(pathr);
1.205     brouard  10836:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10837:       pathr[i-1]='\0';
1.205     brouard  10838:     }
                   10839:     i=strlen(pathr);
                   10840:     if( i==0 ){
                   10841:       printf("ERROR Empty parameter file name\n");
                   10842:       goto end;
                   10843:     }
                   10844:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10845:       printf("Pathr |%s|\n",pathr);
                   10846:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10847:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10848:       strcpy (pathtot, val);
                   10849:       if(pathr[0] == '\0') break; /* Dirty */
                   10850:     }
                   10851:   }
1.281     brouard  10852:   else if (argc<=2){
                   10853:     strcpy(pathtot,argv[1]);
                   10854:   }
1.126     brouard  10855:   else{
                   10856:     strcpy(pathtot,argv[1]);
1.281     brouard  10857:     strcpy(z,argv[2]);
                   10858:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10859:   }
                   10860:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10861:   /*cygwin_split_path(pathtot,path,optionfile);
                   10862:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10863:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10864: 
                   10865:   /* Split argv[0], imach program to get pathimach */
                   10866:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10867:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10868:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10869:  /*   strcpy(pathimach,argv[0]); */
                   10870:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10871:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10872:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10873: #ifdef WIN32
                   10874:   _chdir(path); /* Can be a relative path */
                   10875:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10876: #else
1.126     brouard  10877:   chdir(path); /* Can be a relative path */
1.184     brouard  10878:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10879: #endif
                   10880:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10881:   strcpy(command,"mkdir ");
                   10882:   strcat(command,optionfilefiname);
                   10883:   if((outcmd=system(command)) != 0){
1.169     brouard  10884:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10885:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10886:     /* fclose(ficlog); */
                   10887: /*     exit(1); */
                   10888:   }
                   10889: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10890: /*     perror("mkdir"); */
                   10891: /*   } */
                   10892: 
                   10893:   /*-------- arguments in the command line --------*/
                   10894: 
1.186     brouard  10895:   /* Main Log file */
1.126     brouard  10896:   strcat(filelog, optionfilefiname);
                   10897:   strcat(filelog,".log");    /* */
                   10898:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10899:     printf("Problem with logfile %s\n",filelog);
                   10900:     goto end;
                   10901:   }
                   10902:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10903:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10904:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10905:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10906:  path=%s \n\
                   10907:  optionfile=%s\n\
                   10908:  optionfilext=%s\n\
1.156     brouard  10909:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10910: 
1.197     brouard  10911:   syscompilerinfo(1);
1.167     brouard  10912: 
1.126     brouard  10913:   printf("Local time (at start):%s",strstart);
                   10914:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10915:   fflush(ficlog);
                   10916: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10917: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10918: 
                   10919:   /* */
                   10920:   strcpy(fileres,"r");
                   10921:   strcat(fileres, optionfilefiname);
1.201     brouard  10922:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10923:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10924:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10925: 
1.186     brouard  10926:   /* Main ---------arguments file --------*/
1.126     brouard  10927: 
                   10928:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10929:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10930:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10931:     fflush(ficlog);
1.149     brouard  10932:     /* goto end; */
                   10933:     exit(70); 
1.126     brouard  10934:   }
                   10935: 
                   10936:   strcpy(filereso,"o");
1.201     brouard  10937:   strcat(filereso,fileresu);
1.126     brouard  10938:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10939:     printf("Problem with Output resultfile: %s\n", filereso);
                   10940:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10941:     fflush(ficlog);
                   10942:     goto end;
                   10943:   }
1.278     brouard  10944:       /*-------- Rewriting parameter file ----------*/
                   10945:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10946:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10947:   strcat(rfileres,".");    /* */
                   10948:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10949:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10950:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10951:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   10952:     fflush(ficlog);
                   10953:     goto end;
                   10954:   }
                   10955:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  10956: 
1.278     brouard  10957:                                      
1.126     brouard  10958:   /* Reads comments: lines beginning with '#' */
                   10959:   numlinepar=0;
1.277     brouard  10960:   /* Is it a BOM UTF-8 Windows file? */
                   10961:   /* First parameter line */
1.197     brouard  10962:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  10963:     noffset=0;
                   10964:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   10965:     {
                   10966:       noffset=noffset+3;
                   10967:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   10968:     }
                   10969:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   10970:     {
                   10971:       noffset=noffset+2;
                   10972:       printf("# File is an UTF16BE BOM file\n");
                   10973:     }
                   10974:     else if( line[0] == 0 && line[1] == 0)
                   10975:     {
                   10976:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   10977:        noffset=noffset+4;
                   10978:        printf("# File is an UTF16BE BOM file\n");
                   10979:       }
                   10980:     } else{
                   10981:       ;/*printf(" Not a BOM file\n");*/
                   10982:     }
                   10983:   
1.197     brouard  10984:     /* If line starts with a # it is a comment */
1.277     brouard  10985:     if (line[noffset] == '#') {
1.197     brouard  10986:       numlinepar++;
                   10987:       fputs(line,stdout);
                   10988:       fputs(line,ficparo);
1.278     brouard  10989:       fputs(line,ficres);
1.197     brouard  10990:       fputs(line,ficlog);
                   10991:       continue;
                   10992:     }else
                   10993:       break;
                   10994:   }
                   10995:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   10996:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   10997:     if (num_filled != 5) {
                   10998:       printf("Should be 5 parameters\n");
1.283     brouard  10999:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11000:     }
1.126     brouard  11001:     numlinepar++;
1.197     brouard  11002:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11003:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11004:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11005:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11006:   }
                   11007:   /* Second parameter line */
                   11008:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11009:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11010:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11011:     if (line[0] == '#') {
                   11012:       numlinepar++;
1.283     brouard  11013:       printf("%s",line);
                   11014:       fprintf(ficres,"%s",line);
                   11015:       fprintf(ficparo,"%s",line);
                   11016:       fprintf(ficlog,"%s",line);
1.197     brouard  11017:       continue;
                   11018:     }else
                   11019:       break;
                   11020:   }
1.223     brouard  11021:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11022:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11023:     if (num_filled != 11) {
                   11024:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11025:       printf("but line=%s\n",line);
1.283     brouard  11026:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11027:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11028:     }
1.286   ! brouard  11029:     if( lastpass > maxwav){
        !          11030:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
        !          11031:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
        !          11032:       fflush(ficlog);
        !          11033:       goto end;
        !          11034:     }
        !          11035:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11036:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286   ! brouard  11037:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11038:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11039:   }
1.203     brouard  11040:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11041:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11042:   /* Third parameter line */
                   11043:   while(fgets(line, MAXLINE, ficpar)) {
                   11044:     /* If line starts with a # it is a comment */
                   11045:     if (line[0] == '#') {
                   11046:       numlinepar++;
1.283     brouard  11047:       printf("%s",line);
                   11048:       fprintf(ficres,"%s",line);
                   11049:       fprintf(ficparo,"%s",line);
                   11050:       fprintf(ficlog,"%s",line);
1.197     brouard  11051:       continue;
                   11052:     }else
                   11053:       break;
                   11054:   }
1.201     brouard  11055:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11056:     if (num_filled != 1){
                   11057:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11058:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11059:       model[0]='\0';
                   11060:       goto end;
                   11061:     }
                   11062:     else{
                   11063:       if (model[0]=='+'){
                   11064:        for(i=1; i<=strlen(model);i++)
                   11065:          modeltemp[i-1]=model[i];
1.201     brouard  11066:        strcpy(model,modeltemp); 
1.197     brouard  11067:       }
                   11068:     }
1.199     brouard  11069:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11070:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11071:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11072:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11073:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11074:   }
                   11075:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11076:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11077:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11078:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11079:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11080:   fflush(ficlog);
1.190     brouard  11081:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11082:   if(model[0]=='#'){
1.279     brouard  11083:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11084:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11085:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11086:     if(mle != -1){
1.279     brouard  11087:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11088:       exit(1);
                   11089:     }
                   11090:   }
1.126     brouard  11091:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11092:     ungetc(c,ficpar);
                   11093:     fgets(line, MAXLINE, ficpar);
                   11094:     numlinepar++;
1.195     brouard  11095:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11096:       z[0]=line[1];
                   11097:     }
                   11098:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11099:     fputs(line, stdout);
                   11100:     //puts(line);
1.126     brouard  11101:     fputs(line,ficparo);
                   11102:     fputs(line,ficlog);
                   11103:   }
                   11104:   ungetc(c,ficpar);
                   11105: 
                   11106:    
1.145     brouard  11107:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  11108:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   11109:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   11110:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11111:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11112:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11113:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11114:   */
                   11115:   if (strlen(model)>1) 
1.187     brouard  11116:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11117:   else
1.187     brouard  11118:     ncovmodel=2; /* Constant and age */
1.133     brouard  11119:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11120:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11121:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11122:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11123:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11124:     fflush(stdout);
                   11125:     fclose (ficlog);
                   11126:     goto end;
                   11127:   }
1.126     brouard  11128:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11129:   delti=delti3[1][1];
                   11130:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11131:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11132: /* We could also provide initial parameters values giving by simple logistic regression 
                   11133:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11134:       /* for(i=1;i<nlstate;i++){ */
                   11135:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11136:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11137:       /* } */
1.126     brouard  11138:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11139:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11140:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11141:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11142:     fclose (ficparo);
                   11143:     fclose (ficlog);
                   11144:     goto end;
                   11145:     exit(0);
1.220     brouard  11146:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11147:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11148:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11149:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11150:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11151:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11152:     hess=matrix(1,npar,1,npar);
1.220     brouard  11153:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11154:     /* Read guessed parameters */
1.126     brouard  11155:     /* Reads comments: lines beginning with '#' */
                   11156:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11157:       ungetc(c,ficpar);
                   11158:       fgets(line, MAXLINE, ficpar);
                   11159:       numlinepar++;
1.141     brouard  11160:       fputs(line,stdout);
1.126     brouard  11161:       fputs(line,ficparo);
                   11162:       fputs(line,ficlog);
                   11163:     }
                   11164:     ungetc(c,ficpar);
                   11165:     
                   11166:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11167:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11168:     for(i=1; i <=nlstate; i++){
1.234     brouard  11169:       j=0;
1.126     brouard  11170:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11171:        if(jj==i) continue;
                   11172:        j++;
                   11173:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11174:        if ((i1 != i) || (j1 != jj)){
                   11175:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11176: It might be a problem of design; if ncovcol and the model are correct\n \
                   11177: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11178:          exit(1);
                   11179:        }
                   11180:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11181:        if(mle==1)
                   11182:          printf("%1d%1d",i,jj);
                   11183:        fprintf(ficlog,"%1d%1d",i,jj);
                   11184:        for(k=1; k<=ncovmodel;k++){
                   11185:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11186:          if(mle==1){
                   11187:            printf(" %lf",param[i][j][k]);
                   11188:            fprintf(ficlog," %lf",param[i][j][k]);
                   11189:          }
                   11190:          else
                   11191:            fprintf(ficlog," %lf",param[i][j][k]);
                   11192:          fprintf(ficparo," %lf",param[i][j][k]);
                   11193:        }
                   11194:        fscanf(ficpar,"\n");
                   11195:        numlinepar++;
                   11196:        if(mle==1)
                   11197:          printf("\n");
                   11198:        fprintf(ficlog,"\n");
                   11199:        fprintf(ficparo,"\n");
1.126     brouard  11200:       }
                   11201:     }  
                   11202:     fflush(ficlog);
1.234     brouard  11203:     
1.251     brouard  11204:     /* Reads parameters values */
1.126     brouard  11205:     p=param[1][1];
1.251     brouard  11206:     pstart=paramstart[1][1];
1.126     brouard  11207:     
                   11208:     /* Reads comments: lines beginning with '#' */
                   11209:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11210:       ungetc(c,ficpar);
                   11211:       fgets(line, MAXLINE, ficpar);
                   11212:       numlinepar++;
1.141     brouard  11213:       fputs(line,stdout);
1.126     brouard  11214:       fputs(line,ficparo);
                   11215:       fputs(line,ficlog);
                   11216:     }
                   11217:     ungetc(c,ficpar);
                   11218: 
                   11219:     for(i=1; i <=nlstate; i++){
                   11220:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11221:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11222:        if ( (i1-i) * (j1-j) != 0){
                   11223:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11224:          exit(1);
                   11225:        }
                   11226:        printf("%1d%1d",i,j);
                   11227:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11228:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11229:        for(k=1; k<=ncovmodel;k++){
                   11230:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11231:          printf(" %le",delti3[i][j][k]);
                   11232:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11233:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11234:        }
                   11235:        fscanf(ficpar,"\n");
                   11236:        numlinepar++;
                   11237:        printf("\n");
                   11238:        fprintf(ficparo,"\n");
                   11239:        fprintf(ficlog,"\n");
1.126     brouard  11240:       }
                   11241:     }
                   11242:     fflush(ficlog);
1.234     brouard  11243:     
1.145     brouard  11244:     /* Reads covariance matrix */
1.126     brouard  11245:     delti=delti3[1][1];
1.220     brouard  11246:                
                   11247:                
1.126     brouard  11248:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11249:                
1.126     brouard  11250:     /* Reads comments: lines beginning with '#' */
                   11251:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11252:       ungetc(c,ficpar);
                   11253:       fgets(line, MAXLINE, ficpar);
                   11254:       numlinepar++;
1.141     brouard  11255:       fputs(line,stdout);
1.126     brouard  11256:       fputs(line,ficparo);
                   11257:       fputs(line,ficlog);
                   11258:     }
                   11259:     ungetc(c,ficpar);
1.220     brouard  11260:                
1.126     brouard  11261:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11262:     hess=matrix(1,npar,1,npar);
1.131     brouard  11263:     for(i=1; i <=npar; i++)
                   11264:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11265:                
1.194     brouard  11266:     /* Scans npar lines */
1.126     brouard  11267:     for(i=1; i <=npar; i++){
1.226     brouard  11268:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11269:       if(count != 3){
1.226     brouard  11270:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11271: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11272: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11273:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11274: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11275: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11276:        exit(1);
1.220     brouard  11277:       }else{
1.226     brouard  11278:        if(mle==1)
                   11279:          printf("%1d%1d%d",i1,j1,jk);
                   11280:       }
                   11281:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11282:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11283:       for(j=1; j <=i; j++){
1.226     brouard  11284:        fscanf(ficpar," %le",&matcov[i][j]);
                   11285:        if(mle==1){
                   11286:          printf(" %.5le",matcov[i][j]);
                   11287:        }
                   11288:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11289:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11290:       }
                   11291:       fscanf(ficpar,"\n");
                   11292:       numlinepar++;
                   11293:       if(mle==1)
1.220     brouard  11294:                                printf("\n");
1.126     brouard  11295:       fprintf(ficlog,"\n");
                   11296:       fprintf(ficparo,"\n");
                   11297:     }
1.194     brouard  11298:     /* End of read covariance matrix npar lines */
1.126     brouard  11299:     for(i=1; i <=npar; i++)
                   11300:       for(j=i+1;j<=npar;j++)
1.226     brouard  11301:        matcov[i][j]=matcov[j][i];
1.126     brouard  11302:     
                   11303:     if(mle==1)
                   11304:       printf("\n");
                   11305:     fprintf(ficlog,"\n");
                   11306:     
                   11307:     fflush(ficlog);
                   11308:     
                   11309:   }    /* End of mle != -3 */
1.218     brouard  11310:   
1.186     brouard  11311:   /*  Main data
                   11312:    */
1.126     brouard  11313:   n= lastobs;
                   11314:   num=lvector(1,n);
                   11315:   moisnais=vector(1,n);
                   11316:   annais=vector(1,n);
                   11317:   moisdc=vector(1,n);
                   11318:   andc=vector(1,n);
1.220     brouard  11319:   weight=vector(1,n);
1.126     brouard  11320:   agedc=vector(1,n);
                   11321:   cod=ivector(1,n);
1.220     brouard  11322:   for(i=1;i<=n;i++){
1.234     brouard  11323:     num[i]=0;
                   11324:     moisnais[i]=0;
                   11325:     annais[i]=0;
                   11326:     moisdc[i]=0;
                   11327:     andc[i]=0;
                   11328:     agedc[i]=0;
                   11329:     cod[i]=0;
                   11330:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11331:   }
1.126     brouard  11332:   mint=matrix(1,maxwav,1,n);
                   11333:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11334:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11335:   tab=ivector(1,NCOVMAX);
1.144     brouard  11336:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11337:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11338: 
1.136     brouard  11339:   /* Reads data from file datafile */
                   11340:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11341:     goto end;
                   11342: 
                   11343:   /* Calculation of the number of parameters from char model */
1.234     brouard  11344:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11345:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11346:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11347:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11348:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11349:   */
                   11350:   
                   11351:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11352:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11353:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11354:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11355:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11356:   TvarF=ivector(1,NCOVMAX); /*  */
                   11357:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11358:   TvarV=ivector(1,NCOVMAX); /*  */
                   11359:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11360:   TvarA=ivector(1,NCOVMAX); /*  */
                   11361:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11362:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11363:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11364:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11365:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11366:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11367:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11368:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11369:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11370: 
1.230     brouard  11371:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11372:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11373:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11374:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11375:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11376:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11377:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11378:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11379:   */
                   11380:   /* For model-covariate k tells which data-covariate to use but
                   11381:     because this model-covariate is a construction we invent a new column
                   11382:     ncovcol + k1
                   11383:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11384:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11385:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11386:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11387:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11388:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11389:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11390:   */
1.145     brouard  11391:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11392:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11393:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11394:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11395:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11396:                         4 covariates (3 plus signs)
                   11397:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11398:                      */  
1.230     brouard  11399:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11400:                                * individual dummy, fixed or varying:
                   11401:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11402:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11403:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11404:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11405:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11406:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11407:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11408:                                * individual quantitative, fixed or varying:
                   11409:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11410:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11411:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11412: /* Main decodemodel */
                   11413: 
1.187     brouard  11414: 
1.223     brouard  11415:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11416:     goto end;
                   11417: 
1.137     brouard  11418:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11419:     nbwarn++;
                   11420:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11421:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11422:   }
1.136     brouard  11423:     /*  if(mle==1){*/
1.137     brouard  11424:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11425:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11426:   }
                   11427: 
                   11428:     /*-calculation of age at interview from date of interview and age at death -*/
                   11429:   agev=matrix(1,maxwav,1,imx);
                   11430: 
                   11431:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11432:     goto end;
                   11433: 
1.126     brouard  11434: 
1.136     brouard  11435:   agegomp=(int)agemin;
                   11436:   free_vector(moisnais,1,n);
                   11437:   free_vector(annais,1,n);
1.126     brouard  11438:   /* free_matrix(mint,1,maxwav,1,n);
                   11439:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11440:   /* free_vector(moisdc,1,n); */
                   11441:   /* free_vector(andc,1,n); */
1.145     brouard  11442:   /* */
                   11443:   
1.126     brouard  11444:   wav=ivector(1,imx);
1.214     brouard  11445:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11446:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11447:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11448:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11449:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11450:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11451:    
                   11452:   /* Concatenates waves */
1.214     brouard  11453:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11454:      Death is a valid wave (if date is known).
                   11455:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11456:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11457:      and mw[mi+1][i]. dh depends on stepm.
                   11458:   */
                   11459: 
1.126     brouard  11460:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11461:   /* Concatenates waves */
1.145     brouard  11462:  
1.215     brouard  11463:   free_vector(moisdc,1,n);
                   11464:   free_vector(andc,1,n);
                   11465: 
1.126     brouard  11466:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11467:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11468:   ncodemax[1]=1;
1.145     brouard  11469:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11470:   cptcoveff=0;
1.220     brouard  11471:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11472:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11473:   }
                   11474:   
                   11475:   ncovcombmax=pow(2,cptcoveff);
                   11476:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11477:   for(i=1;i<ncovcombmax;i++)
                   11478:     invalidvarcomb[i]=0;
                   11479:   
1.211     brouard  11480:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11481:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11482:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11483:   
1.200     brouard  11484:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11485:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11486:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11487:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11488:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11489:    * (currently 0 or 1) in the data.
                   11490:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11491:    * corresponding modality (h,j).
                   11492:    */
                   11493: 
1.145     brouard  11494:   h=0;
                   11495:   /*if (cptcovn > 0) */
1.126     brouard  11496:   m=pow(2,cptcoveff);
                   11497:  
1.144     brouard  11498:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11499:           * For k=4 covariates, h goes from 1 to m=2**k
                   11500:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11501:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11502:           *     h\k   1     2     3     4
1.143     brouard  11503:           *______________________________  
                   11504:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11505:           *     2     2     1     1     1
                   11506:           *     3 i=2 1     2     1     1
                   11507:           *     4     2     2     1     1
                   11508:           *     5 i=3 1 i=2 1     2     1
                   11509:           *     6     2     1     2     1
                   11510:           *     7 i=4 1     2     2     1
                   11511:           *     8     2     2     2     1
1.197     brouard  11512:           *     9 i=5 1 i=3 1 i=2 1     2
                   11513:           *    10     2     1     1     2
                   11514:           *    11 i=6 1     2     1     2
                   11515:           *    12     2     2     1     2
                   11516:           *    13 i=7 1 i=4 1     2     2    
                   11517:           *    14     2     1     2     2
                   11518:           *    15 i=8 1     2     2     2
                   11519:           *    16     2     2     2     2
1.143     brouard  11520:           */
1.212     brouard  11521:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11522:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11523:      * and the value of each covariate?
                   11524:      * V1=1, V2=1, V3=2, V4=1 ?
                   11525:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11526:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11527:      * In order to get the real value in the data, we use nbcode
                   11528:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11529:      * We are keeping this crazy system in order to be able (in the future?) 
                   11530:      * to have more than 2 values (0 or 1) for a covariate.
                   11531:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11532:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11533:      *              bbbbbbbb
                   11534:      *              76543210     
                   11535:      *   h-1        00000101 (6-1=5)
1.219     brouard  11536:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11537:      *           &
                   11538:      *     1        00000001 (1)
1.219     brouard  11539:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11540:      *          +1= 00000001 =1 
1.211     brouard  11541:      *
                   11542:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11543:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11544:      *    >>k'            11
                   11545:      *          &   00000001
                   11546:      *            = 00000001
                   11547:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11548:      * Reverse h=6 and m=16?
                   11549:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11550:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11551:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11552:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11553:      * V3=decodtabm(14,3,2**4)=2
                   11554:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11555:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11556:      *          &1 000000001
                   11557:      *           = 000000001
                   11558:      *         +1= 000000010 =2
                   11559:      *                  2211
                   11560:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11561:      *                  V3=2
1.220     brouard  11562:                 * codtabm and decodtabm are identical
1.211     brouard  11563:      */
                   11564: 
1.145     brouard  11565: 
                   11566:  free_ivector(Ndum,-1,NCOVMAX);
                   11567: 
                   11568: 
1.126     brouard  11569:     
1.186     brouard  11570:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11571:   strcpy(optionfilegnuplot,optionfilefiname);
                   11572:   if(mle==-3)
1.201     brouard  11573:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11574:   strcat(optionfilegnuplot,".gp");
                   11575: 
                   11576:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11577:     printf("Problem with file %s",optionfilegnuplot);
                   11578:   }
                   11579:   else{
1.204     brouard  11580:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11581:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11582:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11583:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11584:   }
                   11585:   /*  fclose(ficgp);*/
1.186     brouard  11586: 
                   11587: 
                   11588:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11589: 
                   11590:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11591:   if(mle==-3)
1.201     brouard  11592:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11593:   strcat(optionfilehtm,".htm");
                   11594:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11595:     printf("Problem with %s \n",optionfilehtm);
                   11596:     exit(0);
1.126     brouard  11597:   }
                   11598: 
                   11599:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11600:   strcat(optionfilehtmcov,"-cov.htm");
                   11601:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11602:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11603:   }
                   11604:   else{
                   11605:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11606: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11607: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11608:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11609:   }
                   11610: 
1.213     brouard  11611:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11612: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11613: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11614: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11615: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11616: \n\
                   11617: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11618:  <ul><li><h4>Parameter files</h4>\n\
                   11619:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11620:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11621:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11622:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11623:  - Date and time at start: %s</ul>\n",\
                   11624:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11625:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11626:          fileres,fileres,\
                   11627:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11628:   fflush(fichtm);
                   11629: 
                   11630:   strcpy(pathr,path);
                   11631:   strcat(pathr,optionfilefiname);
1.184     brouard  11632: #ifdef WIN32
                   11633:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11634: #else
1.126     brouard  11635:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11636: #endif
                   11637:          
1.126     brouard  11638:   
1.220     brouard  11639:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11640:                 and for any valid combination of covariates
1.126     brouard  11641:      and prints on file fileres'p'. */
1.251     brouard  11642:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11643:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11644: 
                   11645:   fprintf(fichtm,"\n");
1.286   ! brouard  11646:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11647:          ftol, stepm);
                   11648:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11649:   ncurrv=1;
                   11650:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11651:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11652:   ncurrv=i;
                   11653:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
                   11654:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) covariates: ntv=%d ", ntv);
                   11655:   ncurrv=i;
                   11656:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
                   11657:   fprintf(fichtm,"\n<li>Number of quantitative time varying covariates: nqtv=%d ", nqtv);
                   11658:   ncurrv=i;
                   11659:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11660:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11661:           nlstate, ndeath, maxwav, mle, weightopt);
                   11662: 
                   11663:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11664: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11665: 
                   11666:   
                   11667:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11668: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11669: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11670:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11671:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11672:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11673:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11674:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11675:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11676: 
1.126     brouard  11677:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11678:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11679:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11680: 
                   11681:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11682:   /* For mortality only */
1.126     brouard  11683:   if (mle==-3){
1.136     brouard  11684:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11685:     for(i=1;i<=NDIM;i++)
                   11686:       for(j=1;j<=NDIM;j++)
                   11687:        ximort[i][j]=0.;
1.186     brouard  11688:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11689:     cens=ivector(1,n);
                   11690:     ageexmed=vector(1,n);
                   11691:     agecens=vector(1,n);
                   11692:     dcwave=ivector(1,n);
1.223     brouard  11693:                
1.126     brouard  11694:     for (i=1; i<=imx; i++){
                   11695:       dcwave[i]=-1;
                   11696:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11697:        if (s[m][i]>nlstate) {
                   11698:          dcwave[i]=m;
                   11699:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11700:          break;
                   11701:        }
1.126     brouard  11702:     }
1.226     brouard  11703:     
1.126     brouard  11704:     for (i=1; i<=imx; i++) {
                   11705:       if (wav[i]>0){
1.226     brouard  11706:        ageexmed[i]=agev[mw[1][i]][i];
                   11707:        j=wav[i];
                   11708:        agecens[i]=1.; 
                   11709:        
                   11710:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11711:          agecens[i]=agev[mw[j][i]][i];
                   11712:          cens[i]= 1;
                   11713:        }else if (ageexmed[i]< 1) 
                   11714:          cens[i]= -1;
                   11715:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11716:          cens[i]=0 ;
1.126     brouard  11717:       }
                   11718:       else cens[i]=-1;
                   11719:     }
                   11720:     
                   11721:     for (i=1;i<=NDIM;i++) {
                   11722:       for (j=1;j<=NDIM;j++)
1.226     brouard  11723:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11724:     }
                   11725:     
1.145     brouard  11726:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11727:     /*printf("%lf %lf", p[1], p[2]);*/
                   11728:     
                   11729:     
1.136     brouard  11730: #ifdef GSL
                   11731:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11732: #else
1.126     brouard  11733:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11734: #endif
1.201     brouard  11735:     strcpy(filerespow,"POW-MORT_"); 
                   11736:     strcat(filerespow,fileresu);
1.126     brouard  11737:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11738:       printf("Problem with resultfile: %s\n", filerespow);
                   11739:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11740:     }
1.136     brouard  11741: #ifdef GSL
                   11742:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11743: #else
1.126     brouard  11744:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11745: #endif
1.126     brouard  11746:     /*  for (i=1;i<=nlstate;i++)
                   11747:        for(j=1;j<=nlstate+ndeath;j++)
                   11748:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11749:     */
                   11750:     fprintf(ficrespow,"\n");
1.136     brouard  11751: #ifdef GSL
                   11752:     /* gsl starts here */ 
                   11753:     T = gsl_multimin_fminimizer_nmsimplex;
                   11754:     gsl_multimin_fminimizer *sfm = NULL;
                   11755:     gsl_vector *ss, *x;
                   11756:     gsl_multimin_function minex_func;
                   11757: 
                   11758:     /* Initial vertex size vector */
                   11759:     ss = gsl_vector_alloc (NDIM);
                   11760:     
                   11761:     if (ss == NULL){
                   11762:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11763:     }
                   11764:     /* Set all step sizes to 1 */
                   11765:     gsl_vector_set_all (ss, 0.001);
                   11766: 
                   11767:     /* Starting point */
1.126     brouard  11768:     
1.136     brouard  11769:     x = gsl_vector_alloc (NDIM);
                   11770:     
                   11771:     if (x == NULL){
                   11772:       gsl_vector_free(ss);
                   11773:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11774:     }
                   11775:   
                   11776:     /* Initialize method and iterate */
                   11777:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11778:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11779:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11780:     gsl_vector_set(x, 0, p[1]);
                   11781:     gsl_vector_set(x, 1, p[2]);
                   11782: 
                   11783:     minex_func.f = &gompertz_f;
                   11784:     minex_func.n = NDIM;
                   11785:     minex_func.params = (void *)&p; /* ??? */
                   11786:     
                   11787:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11788:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11789:     
                   11790:     printf("Iterations beginning .....\n\n");
                   11791:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11792: 
                   11793:     iteri=0;
                   11794:     while (rval == GSL_CONTINUE){
                   11795:       iteri++;
                   11796:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11797:       
                   11798:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11799:       fflush(0);
                   11800:       
                   11801:       if (status) 
                   11802:         break;
                   11803:       
                   11804:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11805:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11806:       
                   11807:       if (rval == GSL_SUCCESS)
                   11808:         printf ("converged to a local maximum at\n");
                   11809:       
                   11810:       printf("%5d ", iteri);
                   11811:       for (it = 0; it < NDIM; it++){
                   11812:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11813:       }
                   11814:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11815:     }
                   11816:     
                   11817:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11818:     
                   11819:     gsl_vector_free(x); /* initial values */
                   11820:     gsl_vector_free(ss); /* inital step size */
                   11821:     for (it=0; it<NDIM; it++){
                   11822:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11823:       fprintf(ficrespow," %.12lf", p[it]);
                   11824:     }
                   11825:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11826: #endif
                   11827: #ifdef POWELL
                   11828:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11829: #endif  
1.126     brouard  11830:     fclose(ficrespow);
                   11831:     
1.203     brouard  11832:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11833: 
                   11834:     for(i=1; i <=NDIM; i++)
                   11835:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11836:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11837:     
                   11838:     printf("\nCovariance matrix\n ");
1.203     brouard  11839:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11840:     for(i=1; i <=NDIM; i++) {
                   11841:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11842:                                printf("%f ",matcov[i][j]);
                   11843:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11844:       }
1.203     brouard  11845:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11846:     }
                   11847:     
                   11848:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11849:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11850:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11851:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11852:     }
1.126     brouard  11853:     lsurv=vector(1,AGESUP);
                   11854:     lpop=vector(1,AGESUP);
                   11855:     tpop=vector(1,AGESUP);
                   11856:     lsurv[agegomp]=100000;
                   11857:     
                   11858:     for (k=agegomp;k<=AGESUP;k++) {
                   11859:       agemortsup=k;
                   11860:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11861:     }
                   11862:     
                   11863:     for (k=agegomp;k<agemortsup;k++)
                   11864:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11865:     
                   11866:     for (k=agegomp;k<agemortsup;k++){
                   11867:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11868:       sumlpop=sumlpop+lpop[k];
                   11869:     }
                   11870:     
                   11871:     tpop[agegomp]=sumlpop;
                   11872:     for (k=agegomp;k<(agemortsup-3);k++){
                   11873:       /*  tpop[k+1]=2;*/
                   11874:       tpop[k+1]=tpop[k]-lpop[k];
                   11875:     }
                   11876:     
                   11877:     
                   11878:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11879:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11880:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11881:     
                   11882:     
                   11883:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11884:                ageminpar=50;
                   11885:                agemaxpar=100;
1.194     brouard  11886:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11887:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11888: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11889: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11890:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11891: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11892: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11893:     }else{
                   11894:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11895:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11896:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11897:                }
1.201     brouard  11898:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11899:                     stepm, weightopt,\
                   11900:                     model,imx,p,matcov,agemortsup);
                   11901:     
                   11902:     free_vector(lsurv,1,AGESUP);
                   11903:     free_vector(lpop,1,AGESUP);
                   11904:     free_vector(tpop,1,AGESUP);
1.220     brouard  11905:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11906:     free_ivector(cens,1,n);
                   11907:     free_vector(agecens,1,n);
                   11908:     free_ivector(dcwave,1,n);
1.220     brouard  11909: #ifdef GSL
1.136     brouard  11910: #endif
1.186     brouard  11911:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11912:   /* Standard  */
                   11913:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11914:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11915:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11916:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11917:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11918:     for (k=1; k<=npar;k++)
                   11919:       printf(" %d %8.5f",k,p[k]);
                   11920:     printf("\n");
1.205     brouard  11921:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11922:       /* mlikeli uses func not funcone */
1.247     brouard  11923:       /* for(i=1;i<nlstate;i++){ */
                   11924:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11925:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11926:       /* } */
1.205     brouard  11927:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11928:     }
                   11929:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11930:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11931:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11932:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11933:     }
                   11934:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11935:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11936:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11937:     for (k=1; k<=npar;k++)
                   11938:       printf(" %d %8.5f",k,p[k]);
                   11939:     printf("\n");
                   11940:     
                   11941:     /*--------- results files --------------*/
1.283     brouard  11942:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  11943:     
                   11944:     
                   11945:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11946:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11947:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11948:     for(i=1,jk=1; i <=nlstate; i++){
                   11949:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11950:        if (k != i) {
                   11951:          printf("%d%d ",i,k);
                   11952:          fprintf(ficlog,"%d%d ",i,k);
                   11953:          fprintf(ficres,"%1d%1d ",i,k);
                   11954:          for(j=1; j <=ncovmodel; j++){
                   11955:            printf("%12.7f ",p[jk]);
                   11956:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11957:            fprintf(ficres,"%12.7f ",p[jk]);
                   11958:            jk++; 
                   11959:          }
                   11960:          printf("\n");
                   11961:          fprintf(ficlog,"\n");
                   11962:          fprintf(ficres,"\n");
                   11963:        }
1.126     brouard  11964:       }
                   11965:     }
1.203     brouard  11966:     if(mle != 0){
                   11967:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11968:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11969:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11970:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11971:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11972:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11973:        for(k=1; k <=(nlstate+ndeath); k++){
                   11974:          if (k != i) {
                   11975:            printf("%d%d ",i,k);
                   11976:            fprintf(ficlog,"%d%d ",i,k);
                   11977:            for(j=1; j <=ncovmodel; j++){
                   11978:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11979:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   11980:              jk++; 
                   11981:            }
                   11982:            printf("\n");
                   11983:            fprintf(ficlog,"\n");
                   11984:          }
                   11985:        }
1.193     brouard  11986:       }
1.203     brouard  11987:     } /* end of hesscov and Wald tests */
1.225     brouard  11988:     
1.203     brouard  11989:     /*  */
1.126     brouard  11990:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   11991:     printf("# Scales (for hessian or gradient estimation)\n");
                   11992:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   11993:     for(i=1,jk=1; i <=nlstate; i++){
                   11994:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  11995:        if (j!=i) {
                   11996:          fprintf(ficres,"%1d%1d",i,j);
                   11997:          printf("%1d%1d",i,j);
                   11998:          fprintf(ficlog,"%1d%1d",i,j);
                   11999:          for(k=1; k<=ncovmodel;k++){
                   12000:            printf(" %.5e",delti[jk]);
                   12001:            fprintf(ficlog," %.5e",delti[jk]);
                   12002:            fprintf(ficres," %.5e",delti[jk]);
                   12003:            jk++;
                   12004:          }
                   12005:          printf("\n");
                   12006:          fprintf(ficlog,"\n");
                   12007:          fprintf(ficres,"\n");
                   12008:        }
1.126     brouard  12009:       }
                   12010:     }
                   12011:     
                   12012:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12013:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12014:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12015:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12016:     /* # 121 Var(a12)\n\ */
                   12017:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12018:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12019:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12020:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12021:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12022:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12023:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12024:     
                   12025:     
                   12026:     /* Just to have a covariance matrix which will be more understandable
                   12027:        even is we still don't want to manage dictionary of variables
                   12028:     */
                   12029:     for(itimes=1;itimes<=2;itimes++){
                   12030:       jj=0;
                   12031:       for(i=1; i <=nlstate; i++){
1.225     brouard  12032:        for(j=1; j <=nlstate+ndeath; j++){
                   12033:          if(j==i) continue;
                   12034:          for(k=1; k<=ncovmodel;k++){
                   12035:            jj++;
                   12036:            ca[0]= k+'a'-1;ca[1]='\0';
                   12037:            if(itimes==1){
                   12038:              if(mle>=1)
                   12039:                printf("#%1d%1d%d",i,j,k);
                   12040:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12041:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12042:            }else{
                   12043:              if(mle>=1)
                   12044:                printf("%1d%1d%d",i,j,k);
                   12045:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12046:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12047:            }
                   12048:            ll=0;
                   12049:            for(li=1;li <=nlstate; li++){
                   12050:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12051:                if(lj==li) continue;
                   12052:                for(lk=1;lk<=ncovmodel;lk++){
                   12053:                  ll++;
                   12054:                  if(ll<=jj){
                   12055:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12056:                    if(ll<jj){
                   12057:                      if(itimes==1){
                   12058:                        if(mle>=1)
                   12059:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12060:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12061:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12062:                      }else{
                   12063:                        if(mle>=1)
                   12064:                          printf(" %.5e",matcov[jj][ll]); 
                   12065:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12066:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12067:                      }
                   12068:                    }else{
                   12069:                      if(itimes==1){
                   12070:                        if(mle>=1)
                   12071:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12072:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12073:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12074:                      }else{
                   12075:                        if(mle>=1)
                   12076:                          printf(" %.7e",matcov[jj][ll]); 
                   12077:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12078:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12079:                      }
                   12080:                    }
                   12081:                  }
                   12082:                } /* end lk */
                   12083:              } /* end lj */
                   12084:            } /* end li */
                   12085:            if(mle>=1)
                   12086:              printf("\n");
                   12087:            fprintf(ficlog,"\n");
                   12088:            fprintf(ficres,"\n");
                   12089:            numlinepar++;
                   12090:          } /* end k*/
                   12091:        } /*end j */
1.126     brouard  12092:       } /* end i */
                   12093:     } /* end itimes */
                   12094:     
                   12095:     fflush(ficlog);
                   12096:     fflush(ficres);
1.225     brouard  12097:     while(fgets(line, MAXLINE, ficpar)) {
                   12098:       /* If line starts with a # it is a comment */
                   12099:       if (line[0] == '#') {
                   12100:        numlinepar++;
                   12101:        fputs(line,stdout);
                   12102:        fputs(line,ficparo);
                   12103:        fputs(line,ficlog);
                   12104:        continue;
                   12105:       }else
                   12106:        break;
                   12107:     }
                   12108:     
1.209     brouard  12109:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12110:     /*   ungetc(c,ficpar); */
                   12111:     /*   fgets(line, MAXLINE, ficpar); */
                   12112:     /*   fputs(line,stdout); */
                   12113:     /*   fputs(line,ficparo); */
                   12114:     /* } */
                   12115:     /* ungetc(c,ficpar); */
1.126     brouard  12116:     
                   12117:     estepm=0;
1.209     brouard  12118:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12119:       
                   12120:       if (num_filled != 6) {
                   12121:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12122:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12123:        goto end;
                   12124:       }
                   12125:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12126:     }
                   12127:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12128:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12129:     
1.209     brouard  12130:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12131:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12132:     if (fage <= 2) {
                   12133:       bage = ageminpar;
                   12134:       fage = agemaxpar;
                   12135:     }
                   12136:     
                   12137:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12138:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12139:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12140:                
1.186     brouard  12141:     /* Other stuffs, more or less useful */    
1.254     brouard  12142:     while(fgets(line, MAXLINE, ficpar)) {
                   12143:       /* If line starts with a # it is a comment */
                   12144:       if (line[0] == '#') {
                   12145:        numlinepar++;
                   12146:        fputs(line,stdout);
                   12147:        fputs(line,ficparo);
                   12148:        fputs(line,ficlog);
                   12149:        continue;
                   12150:       }else
                   12151:        break;
                   12152:     }
                   12153: 
                   12154:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12155:       
                   12156:       if (num_filled != 7) {
                   12157:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12158:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12159:        goto end;
                   12160:       }
                   12161:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12162:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12163:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12164:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12165:     }
1.254     brouard  12166: 
                   12167:     while(fgets(line, MAXLINE, ficpar)) {
                   12168:       /* If line starts with a # it is a comment */
                   12169:       if (line[0] == '#') {
                   12170:        numlinepar++;
                   12171:        fputs(line,stdout);
                   12172:        fputs(line,ficparo);
                   12173:        fputs(line,ficlog);
                   12174:        continue;
                   12175:       }else
                   12176:        break;
1.126     brouard  12177:     }
                   12178:     
                   12179:     
                   12180:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12181:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12182:     
1.254     brouard  12183:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12184:       if (num_filled != 1) {
                   12185:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12186:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12187:        goto end;
                   12188:       }
                   12189:       printf("pop_based=%d\n",popbased);
                   12190:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12191:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12192:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12193:     }
                   12194:      
1.258     brouard  12195:     /* Results */
                   12196:     nresult=0;
                   12197:     do{
                   12198:       if(!fgets(line, MAXLINE, ficpar)){
                   12199:        endishere=1;
                   12200:        parameterline=14;
                   12201:       }else if (line[0] == '#') {
                   12202:        /* If line starts with a # it is a comment */
1.254     brouard  12203:        numlinepar++;
                   12204:        fputs(line,stdout);
                   12205:        fputs(line,ficparo);
                   12206:        fputs(line,ficlog);
                   12207:        continue;
1.258     brouard  12208:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12209:        parameterline=11;
                   12210:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12211:        parameterline=12;
                   12212:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12213:        parameterline=13;
                   12214:       else{
                   12215:        parameterline=14;
1.254     brouard  12216:       }
1.258     brouard  12217:       switch (parameterline){ 
                   12218:       case 11:
                   12219:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12220:          if (num_filled != 8) {
                   12221:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12222:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12223:            goto end;
                   12224:          }
                   12225:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12226:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12227:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12228:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12229:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12230:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12231:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12232: 
1.258     brouard  12233:        }
1.254     brouard  12234:        break;
1.258     brouard  12235:       case 12:
                   12236:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12237:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12238:          if (num_filled != 8) {
1.262     brouard  12239:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12240:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12241:            goto end;
                   12242:          }
                   12243:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12244:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12245:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12246:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12247:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12248:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12249:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12250:        }
1.230     brouard  12251:        break;
1.258     brouard  12252:       case 13:
                   12253:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12254:          if (num_filled == 0){
                   12255:            resultline[0]='\0';
                   12256:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12257:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12258:            break;
                   12259:          } else if (num_filled != 1){
                   12260:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12261:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12262:          }
                   12263:          nresult++; /* Sum of resultlines */
                   12264:          printf("Result %d: result=%s\n",nresult, resultline);
                   12265:          if(nresult > MAXRESULTLINES){
                   12266:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12267:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12268:            goto end;
                   12269:          }
                   12270:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12271:          fprintf(ficparo,"result: %s\n",resultline);
                   12272:          fprintf(ficres,"result: %s\n",resultline);
                   12273:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12274:          break;
1.258     brouard  12275:        case 14: 
1.259     brouard  12276:          if(ncovmodel >2 && nresult==0 ){
                   12277:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12278:            goto end;
                   12279:          }
1.259     brouard  12280:          break;
1.258     brouard  12281:        default:
                   12282:          nresult=1;
                   12283:          decoderesult(".",nresult ); /* No covariate */
                   12284:        }
                   12285:       } /* End switch parameterline */
                   12286:     }while(endishere==0); /* End do */
1.126     brouard  12287:     
1.230     brouard  12288:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12289:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12290:     
                   12291:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12292:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12293:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12294: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12295: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12296:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12297: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12298: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12299:     }else{
1.270     brouard  12300:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12301:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12302:     }
                   12303:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12304:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12305:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12306:                
1.225     brouard  12307:     /*------------ free_vector  -------------*/
                   12308:     /*  chdir(path); */
1.220     brouard  12309:                
1.215     brouard  12310:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12311:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12312:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12313:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12314:     free_lvector(num,1,n);
                   12315:     free_vector(agedc,1,n);
                   12316:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12317:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12318:     fclose(ficparo);
                   12319:     fclose(ficres);
1.220     brouard  12320:                
                   12321:                
1.186     brouard  12322:     /* Other results (useful)*/
1.220     brouard  12323:                
                   12324:                
1.126     brouard  12325:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12326:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12327:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12328:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12329:     fclose(ficrespl);
                   12330: 
                   12331:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12332:     /*#include "hpijx.h"*/
                   12333:     hPijx(p, bage, fage);
1.145     brouard  12334:     fclose(ficrespij);
1.227     brouard  12335:     
1.220     brouard  12336:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12337:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12338:     k=1;
1.126     brouard  12339:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12340:     
1.269     brouard  12341:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12342:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12343:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12344:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12345:        for(k=1;k<=ncovcombmax;k++)
                   12346:          probs[i][j][k]=0.;
1.269     brouard  12347:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12348:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12349:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12350:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12351:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12352:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12353:          for(k=1;k<=ncovcombmax;k++)
                   12354:            mobaverages[i][j][k]=0.;
1.219     brouard  12355:       mobaverage=mobaverages;
                   12356:       if (mobilav!=0) {
1.235     brouard  12357:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12358:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12359:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12360:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12361:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12362:        }
1.269     brouard  12363:       } else if (mobilavproj !=0) {
1.235     brouard  12364:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12365:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12366:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12367:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12368:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12369:        }
1.269     brouard  12370:       }else{
                   12371:        printf("Internal error moving average\n");
                   12372:        fflush(stdout);
                   12373:        exit(1);
1.219     brouard  12374:       }
                   12375:     }/* end if moving average */
1.227     brouard  12376:     
1.126     brouard  12377:     /*---------- Forecasting ------------------*/
                   12378:     if(prevfcast==1){
                   12379:       /*    if(stepm ==1){*/
1.269     brouard  12380:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12381:     }
1.269     brouard  12382: 
                   12383:     /* Backcasting */
1.217     brouard  12384:     if(backcast==1){
1.219     brouard  12385:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12386:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12387:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12388: 
                   12389:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12390: 
                   12391:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12392: 
1.219     brouard  12393:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12394:       fclose(ficresplb);
                   12395: 
1.222     brouard  12396:       hBijx(p, bage, fage, mobaverage);
                   12397:       fclose(ficrespijb);
1.219     brouard  12398: 
1.269     brouard  12399:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12400:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12401:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12402: 
                   12403:       
1.269     brouard  12404:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12405:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12406:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12407:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12408:     }    /* end  Backcasting */
1.268     brouard  12409:  
1.186     brouard  12410:  
                   12411:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12412: 
1.215     brouard  12413:     free_ivector(wav,1,imx);
                   12414:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12415:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12416:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12417:                
                   12418:                
1.127     brouard  12419:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12420:                
1.201     brouard  12421:     strcpy(filerese,"E_");
                   12422:     strcat(filerese,fileresu);
1.126     brouard  12423:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12424:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12425:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12426:     }
1.208     brouard  12427:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12428:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12429: 
                   12430:     pstamp(ficreseij);
1.219     brouard  12431:                
1.235     brouard  12432:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12433:     if (cptcovn < 1){i1=1;}
                   12434:     
                   12435:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12436:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12437:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12438:        continue;
1.219     brouard  12439:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12440:       printf("\n#****** ");
1.225     brouard  12441:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12442:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12443:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12444:       }
                   12445:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12446:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12447:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12448:       }
                   12449:       fprintf(ficreseij,"******\n");
1.235     brouard  12450:       printf("******\n");
1.219     brouard  12451:       
                   12452:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12453:       oldm=oldms;savm=savms;
1.235     brouard  12454:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12455:       
1.219     brouard  12456:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12457:     }
                   12458:     fclose(ficreseij);
1.208     brouard  12459:     printf("done evsij\n");fflush(stdout);
                   12460:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12461: 
1.218     brouard  12462:                
1.227     brouard  12463:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12464:                
1.201     brouard  12465:     strcpy(filerest,"T_");
                   12466:     strcat(filerest,fileresu);
1.127     brouard  12467:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12468:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12469:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12470:     }
1.208     brouard  12471:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12472:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12473:     strcpy(fileresstde,"STDE_");
                   12474:     strcat(fileresstde,fileresu);
1.126     brouard  12475:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12476:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12477:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12478:     }
1.227     brouard  12479:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12480:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12481: 
1.201     brouard  12482:     strcpy(filerescve,"CVE_");
                   12483:     strcat(filerescve,fileresu);
1.126     brouard  12484:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12485:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12486:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12487:     }
1.227     brouard  12488:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12489:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12490: 
1.201     brouard  12491:     strcpy(fileresv,"V_");
                   12492:     strcat(fileresv,fileresu);
1.126     brouard  12493:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12494:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12495:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12496:     }
1.227     brouard  12497:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12498:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12499: 
1.235     brouard  12500:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12501:     if (cptcovn < 1){i1=1;}
                   12502:     
                   12503:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12504:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12505:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12506:        continue;
1.242     brouard  12507:       printf("\n#****** Result for:");
                   12508:       fprintf(ficrest,"\n#****** Result for:");
                   12509:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12510:       for(j=1;j<=cptcoveff;j++){ 
                   12511:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12512:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12513:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12514:       }
1.235     brouard  12515:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12516:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12517:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12518:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12519:       }        
1.208     brouard  12520:       fprintf(ficrest,"******\n");
1.227     brouard  12521:       fprintf(ficlog,"******\n");
                   12522:       printf("******\n");
1.208     brouard  12523:       
                   12524:       fprintf(ficresstdeij,"\n#****** ");
                   12525:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12526:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12527:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12528:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12529:       }
1.235     brouard  12530:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12531:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12532:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12533:       }        
1.208     brouard  12534:       fprintf(ficresstdeij,"******\n");
                   12535:       fprintf(ficrescveij,"******\n");
                   12536:       
                   12537:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12538:       /* pstamp(ficresvij); */
1.225     brouard  12539:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12540:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12541:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12542:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12543:       }        
1.208     brouard  12544:       fprintf(ficresvij,"******\n");
                   12545:       
                   12546:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12547:       oldm=oldms;savm=savms;
1.235     brouard  12548:       printf(" cvevsij ");
                   12549:       fprintf(ficlog, " cvevsij ");
                   12550:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12551:       printf(" end cvevsij \n ");
                   12552:       fprintf(ficlog, " end cvevsij \n ");
                   12553:       
                   12554:       /*
                   12555:        */
                   12556:       /* goto endfree; */
                   12557:       
                   12558:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12559:       pstamp(ficrest);
                   12560:       
1.269     brouard  12561:       epj=vector(1,nlstate+1);
1.208     brouard  12562:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12563:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12564:        cptcod= 0; /* To be deleted */
                   12565:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12566:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12567:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12568:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12569:        if(vpopbased==1)
                   12570:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12571:        else
                   12572:          fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
                   12573:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12574:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12575:        fprintf(ficrest,"\n");
                   12576:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
                   12577:        printf("Computing age specific period (stable) prevalences in each health state \n");
                   12578:        fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
                   12579:        for(age=bage; age <=fage ;age++){
1.235     brouard  12580:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12581:          if (vpopbased==1) {
                   12582:            if(mobilav ==0){
                   12583:              for(i=1; i<=nlstate;i++)
                   12584:                prlim[i][i]=probs[(int)age][i][k];
                   12585:            }else{ /* mobilav */ 
                   12586:              for(i=1; i<=nlstate;i++)
                   12587:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12588:            }
                   12589:          }
1.219     brouard  12590:          
1.227     brouard  12591:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12592:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12593:          /* printf(" age %4.0f ",age); */
                   12594:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12595:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12596:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12597:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12598:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12599:            }
                   12600:            epj[nlstate+1] +=epj[j];
                   12601:          }
                   12602:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12603:          
1.227     brouard  12604:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12605:            for(j=1;j <=nlstate;j++)
                   12606:              vepp += vareij[i][j][(int)age];
                   12607:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12608:          for(j=1;j <=nlstate;j++){
                   12609:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12610:          }
                   12611:          fprintf(ficrest,"\n");
                   12612:        }
1.208     brouard  12613:       } /* End vpopbased */
1.269     brouard  12614:       free_vector(epj,1,nlstate+1);
1.208     brouard  12615:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12616:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12617:       printf("done selection\n");fflush(stdout);
                   12618:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12619:       
1.235     brouard  12620:     } /* End k selection */
1.227     brouard  12621: 
                   12622:     printf("done State-specific expectancies\n");fflush(stdout);
                   12623:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12624: 
1.269     brouard  12625:     /* variance-covariance of period prevalence*/
                   12626:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12627: 
1.227     brouard  12628:     
                   12629:     free_vector(weight,1,n);
                   12630:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12631:     free_imatrix(s,1,maxwav+1,1,n);
                   12632:     free_matrix(anint,1,maxwav,1,n); 
                   12633:     free_matrix(mint,1,maxwav,1,n);
                   12634:     free_ivector(cod,1,n);
                   12635:     free_ivector(tab,1,NCOVMAX);
                   12636:     fclose(ficresstdeij);
                   12637:     fclose(ficrescveij);
                   12638:     fclose(ficresvij);
                   12639:     fclose(ficrest);
                   12640:     fclose(ficpar);
                   12641:     
                   12642:     
1.126     brouard  12643:     /*---------- End : free ----------------*/
1.219     brouard  12644:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12645:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12646:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12647:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12648:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12649:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12650:   /* endfree:*/
                   12651:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12652:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12653:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12654:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12655:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12656:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12657:   free_matrix(covar,0,NCOVMAX,1,n);
                   12658:   free_matrix(matcov,1,npar,1,npar);
                   12659:   free_matrix(hess,1,npar,1,npar);
                   12660:   /*free_vector(delti,1,npar);*/
                   12661:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12662:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12663:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12664:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12665:   
                   12666:   free_ivector(ncodemax,1,NCOVMAX);
                   12667:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12668:   free_ivector(Dummy,-1,NCOVMAX);
                   12669:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12670:   free_ivector(DummyV,1,NCOVMAX);
                   12671:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12672:   free_ivector(Typevar,-1,NCOVMAX);
                   12673:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12674:   free_ivector(TvarsQ,1,NCOVMAX);
                   12675:   free_ivector(TvarsQind,1,NCOVMAX);
                   12676:   free_ivector(TvarsD,1,NCOVMAX);
                   12677:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12678:   free_ivector(TvarFD,1,NCOVMAX);
                   12679:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12680:   free_ivector(TvarF,1,NCOVMAX);
                   12681:   free_ivector(TvarFind,1,NCOVMAX);
                   12682:   free_ivector(TvarV,1,NCOVMAX);
                   12683:   free_ivector(TvarVind,1,NCOVMAX);
                   12684:   free_ivector(TvarA,1,NCOVMAX);
                   12685:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12686:   free_ivector(TvarFQ,1,NCOVMAX);
                   12687:   free_ivector(TvarFQind,1,NCOVMAX);
                   12688:   free_ivector(TvarVD,1,NCOVMAX);
                   12689:   free_ivector(TvarVDind,1,NCOVMAX);
                   12690:   free_ivector(TvarVQ,1,NCOVMAX);
                   12691:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12692:   free_ivector(Tvarsel,1,NCOVMAX);
                   12693:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12694:   free_ivector(Tposprod,1,NCOVMAX);
                   12695:   free_ivector(Tprod,1,NCOVMAX);
                   12696:   free_ivector(Tvaraff,1,NCOVMAX);
                   12697:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12698:   free_ivector(Tage,1,NCOVMAX);
                   12699:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12700:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12701:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12702:   
                   12703:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12704:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12705:   fflush(fichtm);
                   12706:   fflush(ficgp);
                   12707:   
1.227     brouard  12708:   
1.126     brouard  12709:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12710:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12711:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12712:   }else{
                   12713:     printf("End of Imach\n");
                   12714:     fprintf(ficlog,"End of Imach\n");
                   12715:   }
                   12716:   printf("See log file on %s\n",filelog);
                   12717:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12718:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12719:   rend_time = time(NULL);  
                   12720:   end_time = *localtime(&rend_time);
                   12721:   /* tml = *localtime(&end_time.tm_sec); */
                   12722:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12723:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12724:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12725:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12726:   
1.157     brouard  12727:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12728:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12729:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12730:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12731: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12732:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12733:   fclose(fichtm);
                   12734:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12735:   fclose(fichtmcov);
                   12736:   fclose(ficgp);
                   12737:   fclose(ficlog);
                   12738:   /*------ End -----------*/
1.227     brouard  12739:   
1.281     brouard  12740: 
                   12741: /* Executes gnuplot */
1.227     brouard  12742:   
                   12743:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12744: #ifdef WIN32
1.227     brouard  12745:   if (_chdir(pathcd) != 0)
                   12746:     printf("Can't move to directory %s!\n",path);
                   12747:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12748: #else
1.227     brouard  12749:     if(chdir(pathcd) != 0)
                   12750:       printf("Can't move to directory %s!\n", path);
                   12751:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12752: #endif 
1.126     brouard  12753:     printf("Current directory %s!\n",pathcd);
                   12754:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12755:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12756: #ifdef _WIN32
1.126     brouard  12757:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12758: #endif
                   12759:   if(!stat(plotcmd,&info)){
1.158     brouard  12760:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12761:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12762:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12763:     }else
                   12764:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12765: #ifdef __unix
1.126     brouard  12766:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12767:     if(!stat(plotcmd,&info)){
1.158     brouard  12768:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12769:     }else
                   12770:       strcpy(pplotcmd,plotcmd);
                   12771: #endif
                   12772:   }else
                   12773:     strcpy(pplotcmd,plotcmd);
                   12774:   
                   12775:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12776:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12777:   
1.126     brouard  12778:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12779:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12780:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12781:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12782:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12783:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12784:   }
1.158     brouard  12785:   printf(" Successful, please wait...");
1.126     brouard  12786:   while (z[0] != 'q') {
                   12787:     /* chdir(path); */
1.154     brouard  12788:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12789:     scanf("%s",z);
                   12790: /*     if (z[0] == 'c') system("./imach"); */
                   12791:     if (z[0] == 'e') {
1.158     brouard  12792: #ifdef __APPLE__
1.152     brouard  12793:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12794: #elif __linux
                   12795:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12796: #else
1.152     brouard  12797:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12798: #endif
                   12799:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12800:       system(pplotcmd);
1.126     brouard  12801:     }
                   12802:     else if (z[0] == 'g') system(plotcmd);
                   12803:     else if (z[0] == 'q') exit(0);
                   12804:   }
1.227     brouard  12805: end:
1.126     brouard  12806:   while (z[0] != 'q') {
1.195     brouard  12807:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12808:     scanf("%s",z);
                   12809:   }
1.283     brouard  12810:   printf("End\n");
1.282     brouard  12811:   exit(0);
1.126     brouard  12812: }

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