Annotation of imach/src/imach.c, revision 1.288

1.288   ! brouard     1: /* $Id: imach.c,v 1.287 2018/05/01 17:57:25 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.288   ! brouard     4:   Revision 1.287  2018/05/01 17:57:25  brouard
        !             5:   Summary: Bug fixed by providing frequencies only for non missing covariates
        !             6: 
1.287     brouard     7:   Revision 1.286  2018/04/27 14:27:04  brouard
                      8:   Summary: some minor bugs
                      9: 
1.286     brouard    10:   Revision 1.285  2018/04/21 21:02:16  brouard
                     11:   Summary: Some bugs fixed, valgrind tested
                     12: 
1.285     brouard    13:   Revision 1.284  2018/04/20 05:22:13  brouard
                     14:   Summary: Computing mean and stdeviation of fixed quantitative variables
                     15: 
1.284     brouard    16:   Revision 1.283  2018/04/19 14:49:16  brouard
                     17:   Summary: Some minor bugs fixed
                     18: 
1.283     brouard    19:   Revision 1.282  2018/02/27 22:50:02  brouard
                     20:   *** empty log message ***
                     21: 
1.282     brouard    22:   Revision 1.281  2018/02/27 19:25:23  brouard
                     23:   Summary: Adding second argument for quitting
                     24: 
1.281     brouard    25:   Revision 1.280  2018/02/21 07:58:13  brouard
                     26:   Summary: 0.99r15
                     27: 
                     28:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     29: 
1.280     brouard    30:   Revision 1.279  2017/07/20 13:35:01  brouard
                     31:   Summary: temporary working
                     32: 
1.279     brouard    33:   Revision 1.278  2017/07/19 14:09:02  brouard
                     34:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     35: 
1.278     brouard    36:   Revision 1.277  2017/07/17 08:53:49  brouard
                     37:   Summary: BOM files can be read now
                     38: 
1.277     brouard    39:   Revision 1.276  2017/06/30 15:48:31  brouard
                     40:   Summary: Graphs improvements
                     41: 
1.276     brouard    42:   Revision 1.275  2017/06/30 13:39:33  brouard
                     43:   Summary: Saito's color
                     44: 
1.275     brouard    45:   Revision 1.274  2017/06/29 09:47:08  brouard
                     46:   Summary: Version 0.99r14
                     47: 
1.274     brouard    48:   Revision 1.273  2017/06/27 11:06:02  brouard
                     49:   Summary: More documentation on projections
                     50: 
1.273     brouard    51:   Revision 1.272  2017/06/27 10:22:40  brouard
                     52:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     53: 
1.272     brouard    54:   Revision 1.271  2017/06/27 10:17:50  brouard
                     55:   Summary: Some bug with rint
                     56: 
1.271     brouard    57:   Revision 1.270  2017/05/24 05:45:29  brouard
                     58:   *** empty log message ***
                     59: 
1.270     brouard    60:   Revision 1.269  2017/05/23 08:39:25  brouard
                     61:   Summary: Code into subroutine, cleanings
                     62: 
1.269     brouard    63:   Revision 1.268  2017/05/18 20:09:32  brouard
                     64:   Summary: backprojection and confidence intervals of backprevalence
                     65: 
1.268     brouard    66:   Revision 1.267  2017/05/13 10:25:05  brouard
                     67:   Summary: temporary save for backprojection
                     68: 
1.267     brouard    69:   Revision 1.266  2017/05/13 07:26:12  brouard
                     70:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     71: 
1.266     brouard    72:   Revision 1.265  2017/04/26 16:22:11  brouard
                     73:   Summary: imach 0.99r13 Some bugs fixed
                     74: 
1.265     brouard    75:   Revision 1.264  2017/04/26 06:01:29  brouard
                     76:   Summary: Labels in graphs
                     77: 
1.264     brouard    78:   Revision 1.263  2017/04/24 15:23:15  brouard
                     79:   Summary: to save
                     80: 
1.263     brouard    81:   Revision 1.262  2017/04/18 16:48:12  brouard
                     82:   *** empty log message ***
                     83: 
1.262     brouard    84:   Revision 1.261  2017/04/05 10:14:09  brouard
                     85:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     86: 
1.261     brouard    87:   Revision 1.260  2017/04/04 17:46:59  brouard
                     88:   Summary: Gnuplot indexations fixed (humm)
                     89: 
1.260     brouard    90:   Revision 1.259  2017/04/04 13:01:16  brouard
                     91:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     92: 
1.259     brouard    93:   Revision 1.258  2017/04/03 10:17:47  brouard
                     94:   Summary: Version 0.99r12
                     95: 
                     96:   Some cleanings, conformed with updated documentation.
                     97: 
1.258     brouard    98:   Revision 1.257  2017/03/29 16:53:30  brouard
                     99:   Summary: Temp
                    100: 
1.257     brouard   101:   Revision 1.256  2017/03/27 05:50:23  brouard
                    102:   Summary: Temporary
                    103: 
1.256     brouard   104:   Revision 1.255  2017/03/08 16:02:28  brouard
                    105:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    106: 
1.255     brouard   107:   Revision 1.254  2017/03/08 07:13:00  brouard
                    108:   Summary: Fixing data parameter line
                    109: 
1.254     brouard   110:   Revision 1.253  2016/12/15 11:59:41  brouard
                    111:   Summary: 0.99 in progress
                    112: 
1.253     brouard   113:   Revision 1.252  2016/09/15 21:15:37  brouard
                    114:   *** empty log message ***
                    115: 
1.252     brouard   116:   Revision 1.251  2016/09/15 15:01:13  brouard
                    117:   Summary: not working
                    118: 
1.251     brouard   119:   Revision 1.250  2016/09/08 16:07:27  brouard
                    120:   Summary: continue
                    121: 
1.250     brouard   122:   Revision 1.249  2016/09/07 17:14:18  brouard
                    123:   Summary: Starting values from frequencies
                    124: 
1.249     brouard   125:   Revision 1.248  2016/09/07 14:10:18  brouard
                    126:   *** empty log message ***
                    127: 
1.248     brouard   128:   Revision 1.247  2016/09/02 11:11:21  brouard
                    129:   *** empty log message ***
                    130: 
1.247     brouard   131:   Revision 1.246  2016/09/02 08:49:22  brouard
                    132:   *** empty log message ***
                    133: 
1.246     brouard   134:   Revision 1.245  2016/09/02 07:25:01  brouard
                    135:   *** empty log message ***
                    136: 
1.245     brouard   137:   Revision 1.244  2016/09/02 07:17:34  brouard
                    138:   *** empty log message ***
                    139: 
1.244     brouard   140:   Revision 1.243  2016/09/02 06:45:35  brouard
                    141:   *** empty log message ***
                    142: 
1.243     brouard   143:   Revision 1.242  2016/08/30 15:01:20  brouard
                    144:   Summary: Fixing a lots
                    145: 
1.242     brouard   146:   Revision 1.241  2016/08/29 17:17:25  brouard
                    147:   Summary: gnuplot problem in Back projection to fix
                    148: 
1.241     brouard   149:   Revision 1.240  2016/08/29 07:53:18  brouard
                    150:   Summary: Better
                    151: 
1.240     brouard   152:   Revision 1.239  2016/08/26 15:51:03  brouard
                    153:   Summary: Improvement in Powell output in order to copy and paste
                    154: 
                    155:   Author:
                    156: 
1.239     brouard   157:   Revision 1.238  2016/08/26 14:23:35  brouard
                    158:   Summary: Starting tests of 0.99
                    159: 
1.238     brouard   160:   Revision 1.237  2016/08/26 09:20:19  brouard
                    161:   Summary: to valgrind
                    162: 
1.237     brouard   163:   Revision 1.236  2016/08/25 10:50:18  brouard
                    164:   *** empty log message ***
                    165: 
1.236     brouard   166:   Revision 1.235  2016/08/25 06:59:23  brouard
                    167:   *** empty log message ***
                    168: 
1.235     brouard   169:   Revision 1.234  2016/08/23 16:51:20  brouard
                    170:   *** empty log message ***
                    171: 
1.234     brouard   172:   Revision 1.233  2016/08/23 07:40:50  brouard
                    173:   Summary: not working
                    174: 
1.233     brouard   175:   Revision 1.232  2016/08/22 14:20:21  brouard
                    176:   Summary: not working
                    177: 
1.232     brouard   178:   Revision 1.231  2016/08/22 07:17:15  brouard
                    179:   Summary: not working
                    180: 
1.231     brouard   181:   Revision 1.230  2016/08/22 06:55:53  brouard
                    182:   Summary: Not working
                    183: 
1.230     brouard   184:   Revision 1.229  2016/07/23 09:45:53  brouard
                    185:   Summary: Completing for func too
                    186: 
1.229     brouard   187:   Revision 1.228  2016/07/22 17:45:30  brouard
                    188:   Summary: Fixing some arrays, still debugging
                    189: 
1.227     brouard   190:   Revision 1.226  2016/07/12 18:42:34  brouard
                    191:   Summary: temp
                    192: 
1.226     brouard   193:   Revision 1.225  2016/07/12 08:40:03  brouard
                    194:   Summary: saving but not running
                    195: 
1.225     brouard   196:   Revision 1.224  2016/07/01 13:16:01  brouard
                    197:   Summary: Fixes
                    198: 
1.224     brouard   199:   Revision 1.223  2016/02/19 09:23:35  brouard
                    200:   Summary: temporary
                    201: 
1.223     brouard   202:   Revision 1.222  2016/02/17 08:14:50  brouard
                    203:   Summary: Probably last 0.98 stable version 0.98r6
                    204: 
1.222     brouard   205:   Revision 1.221  2016/02/15 23:35:36  brouard
                    206:   Summary: minor bug
                    207: 
1.220     brouard   208:   Revision 1.219  2016/02/15 00:48:12  brouard
                    209:   *** empty log message ***
                    210: 
1.219     brouard   211:   Revision 1.218  2016/02/12 11:29:23  brouard
                    212:   Summary: 0.99 Back projections
                    213: 
1.218     brouard   214:   Revision 1.217  2015/12/23 17:18:31  brouard
                    215:   Summary: Experimental backcast
                    216: 
1.217     brouard   217:   Revision 1.216  2015/12/18 17:32:11  brouard
                    218:   Summary: 0.98r4 Warning and status=-2
                    219: 
                    220:   Version 0.98r4 is now:
                    221:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    222:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    223:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    224: 
1.216     brouard   225:   Revision 1.215  2015/12/16 08:52:24  brouard
                    226:   Summary: 0.98r4 working
                    227: 
1.215     brouard   228:   Revision 1.214  2015/12/16 06:57:54  brouard
                    229:   Summary: temporary not working
                    230: 
1.214     brouard   231:   Revision 1.213  2015/12/11 18:22:17  brouard
                    232:   Summary: 0.98r4
                    233: 
1.213     brouard   234:   Revision 1.212  2015/11/21 12:47:24  brouard
                    235:   Summary: minor typo
                    236: 
1.212     brouard   237:   Revision 1.211  2015/11/21 12:41:11  brouard
                    238:   Summary: 0.98r3 with some graph of projected cross-sectional
                    239: 
                    240:   Author: Nicolas Brouard
                    241: 
1.211     brouard   242:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   243:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   244:   Summary: Adding ftolpl parameter
                    245:   Author: N Brouard
                    246: 
                    247:   We had difficulties to get smoothed confidence intervals. It was due
                    248:   to the period prevalence which wasn't computed accurately. The inner
                    249:   parameter ftolpl is now an outer parameter of the .imach parameter
                    250:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    251:   computation are long.
                    252: 
1.209     brouard   253:   Revision 1.208  2015/11/17 14:31:57  brouard
                    254:   Summary: temporary
                    255: 
1.208     brouard   256:   Revision 1.207  2015/10/27 17:36:57  brouard
                    257:   *** empty log message ***
                    258: 
1.207     brouard   259:   Revision 1.206  2015/10/24 07:14:11  brouard
                    260:   *** empty log message ***
                    261: 
1.206     brouard   262:   Revision 1.205  2015/10/23 15:50:53  brouard
                    263:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    264: 
1.205     brouard   265:   Revision 1.204  2015/10/01 16:20:26  brouard
                    266:   Summary: Some new graphs of contribution to likelihood
                    267: 
1.204     brouard   268:   Revision 1.203  2015/09/30 17:45:14  brouard
                    269:   Summary: looking at better estimation of the hessian
                    270: 
                    271:   Also a better criteria for convergence to the period prevalence And
                    272:   therefore adding the number of years needed to converge. (The
                    273:   prevalence in any alive state shold sum to one
                    274: 
1.203     brouard   275:   Revision 1.202  2015/09/22 19:45:16  brouard
                    276:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    277: 
1.202     brouard   278:   Revision 1.201  2015/09/15 17:34:58  brouard
                    279:   Summary: 0.98r0
                    280: 
                    281:   - Some new graphs like suvival functions
                    282:   - Some bugs fixed like model=1+age+V2.
                    283: 
1.201     brouard   284:   Revision 1.200  2015/09/09 16:53:55  brouard
                    285:   Summary: Big bug thanks to Flavia
                    286: 
                    287:   Even model=1+age+V2. did not work anymore
                    288: 
1.200     brouard   289:   Revision 1.199  2015/09/07 14:09:23  brouard
                    290:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    291: 
1.199     brouard   292:   Revision 1.198  2015/09/03 07:14:39  brouard
                    293:   Summary: 0.98q5 Flavia
                    294: 
1.198     brouard   295:   Revision 1.197  2015/09/01 18:24:39  brouard
                    296:   *** empty log message ***
                    297: 
1.197     brouard   298:   Revision 1.196  2015/08/18 23:17:52  brouard
                    299:   Summary: 0.98q5
                    300: 
1.196     brouard   301:   Revision 1.195  2015/08/18 16:28:39  brouard
                    302:   Summary: Adding a hack for testing purpose
                    303: 
                    304:   After reading the title, ftol and model lines, if the comment line has
                    305:   a q, starting with #q, the answer at the end of the run is quit. It
                    306:   permits to run test files in batch with ctest. The former workaround was
                    307:   $ echo q | imach foo.imach
                    308: 
1.195     brouard   309:   Revision 1.194  2015/08/18 13:32:00  brouard
                    310:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    311: 
1.194     brouard   312:   Revision 1.193  2015/08/04 07:17:42  brouard
                    313:   Summary: 0.98q4
                    314: 
1.193     brouard   315:   Revision 1.192  2015/07/16 16:49:02  brouard
                    316:   Summary: Fixing some outputs
                    317: 
1.192     brouard   318:   Revision 1.191  2015/07/14 10:00:33  brouard
                    319:   Summary: Some fixes
                    320: 
1.191     brouard   321:   Revision 1.190  2015/05/05 08:51:13  brouard
                    322:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    323: 
                    324:   Fix 1+age+.
                    325: 
1.190     brouard   326:   Revision 1.189  2015/04/30 14:45:16  brouard
                    327:   Summary: 0.98q2
                    328: 
1.189     brouard   329:   Revision 1.188  2015/04/30 08:27:53  brouard
                    330:   *** empty log message ***
                    331: 
1.188     brouard   332:   Revision 1.187  2015/04/29 09:11:15  brouard
                    333:   *** empty log message ***
                    334: 
1.187     brouard   335:   Revision 1.186  2015/04/23 12:01:52  brouard
                    336:   Summary: V1*age is working now, version 0.98q1
                    337: 
                    338:   Some codes had been disabled in order to simplify and Vn*age was
                    339:   working in the optimization phase, ie, giving correct MLE parameters,
                    340:   but, as usual, outputs were not correct and program core dumped.
                    341: 
1.186     brouard   342:   Revision 1.185  2015/03/11 13:26:42  brouard
                    343:   Summary: Inclusion of compile and links command line for Intel Compiler
                    344: 
1.185     brouard   345:   Revision 1.184  2015/03/11 11:52:39  brouard
                    346:   Summary: Back from Windows 8. Intel Compiler
                    347: 
1.184     brouard   348:   Revision 1.183  2015/03/10 20:34:32  brouard
                    349:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    350: 
                    351:   We use directest instead of original Powell test; probably no
                    352:   incidence on the results, but better justifications;
                    353:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    354:   wrong results.
                    355: 
1.183     brouard   356:   Revision 1.182  2015/02/12 08:19:57  brouard
                    357:   Summary: Trying to keep directest which seems simpler and more general
                    358:   Author: Nicolas Brouard
                    359: 
1.182     brouard   360:   Revision 1.181  2015/02/11 23:22:24  brouard
                    361:   Summary: Comments on Powell added
                    362: 
                    363:   Author:
                    364: 
1.181     brouard   365:   Revision 1.180  2015/02/11 17:33:45  brouard
                    366:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    367: 
1.180     brouard   368:   Revision 1.179  2015/01/04 09:57:06  brouard
                    369:   Summary: back to OS/X
                    370: 
1.179     brouard   371:   Revision 1.178  2015/01/04 09:35:48  brouard
                    372:   *** empty log message ***
                    373: 
1.178     brouard   374:   Revision 1.177  2015/01/03 18:40:56  brouard
                    375:   Summary: Still testing ilc32 on OSX
                    376: 
1.177     brouard   377:   Revision 1.176  2015/01/03 16:45:04  brouard
                    378:   *** empty log message ***
                    379: 
1.176     brouard   380:   Revision 1.175  2015/01/03 16:33:42  brouard
                    381:   *** empty log message ***
                    382: 
1.175     brouard   383:   Revision 1.174  2015/01/03 16:15:49  brouard
                    384:   Summary: Still in cross-compilation
                    385: 
1.174     brouard   386:   Revision 1.173  2015/01/03 12:06:26  brouard
                    387:   Summary: trying to detect cross-compilation
                    388: 
1.173     brouard   389:   Revision 1.172  2014/12/27 12:07:47  brouard
                    390:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    391: 
1.172     brouard   392:   Revision 1.171  2014/12/23 13:26:59  brouard
                    393:   Summary: Back from Visual C
                    394: 
                    395:   Still problem with utsname.h on Windows
                    396: 
1.171     brouard   397:   Revision 1.170  2014/12/23 11:17:12  brouard
                    398:   Summary: Cleaning some \%% back to %%
                    399: 
                    400:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    401: 
1.170     brouard   402:   Revision 1.169  2014/12/22 23:08:31  brouard
                    403:   Summary: 0.98p
                    404: 
                    405:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    406: 
1.169     brouard   407:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   408:   Summary: update
1.169     brouard   409: 
1.168     brouard   410:   Revision 1.167  2014/12/22 13:50:56  brouard
                    411:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    412: 
                    413:   Testing on Linux 64
                    414: 
1.167     brouard   415:   Revision 1.166  2014/12/22 11:40:47  brouard
                    416:   *** empty log message ***
                    417: 
1.166     brouard   418:   Revision 1.165  2014/12/16 11:20:36  brouard
                    419:   Summary: After compiling on Visual C
                    420: 
                    421:   * imach.c (Module): Merging 1.61 to 1.162
                    422: 
1.165     brouard   423:   Revision 1.164  2014/12/16 10:52:11  brouard
                    424:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    425: 
                    426:   * imach.c (Module): Merging 1.61 to 1.162
                    427: 
1.164     brouard   428:   Revision 1.163  2014/12/16 10:30:11  brouard
                    429:   * imach.c (Module): Merging 1.61 to 1.162
                    430: 
1.163     brouard   431:   Revision 1.162  2014/09/25 11:43:39  brouard
                    432:   Summary: temporary backup 0.99!
                    433: 
1.162     brouard   434:   Revision 1.1  2014/09/16 11:06:58  brouard
                    435:   Summary: With some code (wrong) for nlopt
                    436: 
                    437:   Author:
                    438: 
                    439:   Revision 1.161  2014/09/15 20:41:41  brouard
                    440:   Summary: Problem with macro SQR on Intel compiler
                    441: 
1.161     brouard   442:   Revision 1.160  2014/09/02 09:24:05  brouard
                    443:   *** empty log message ***
                    444: 
1.160     brouard   445:   Revision 1.159  2014/09/01 10:34:10  brouard
                    446:   Summary: WIN32
                    447:   Author: Brouard
                    448: 
1.159     brouard   449:   Revision 1.158  2014/08/27 17:11:51  brouard
                    450:   *** empty log message ***
                    451: 
1.158     brouard   452:   Revision 1.157  2014/08/27 16:26:55  brouard
                    453:   Summary: Preparing windows Visual studio version
                    454:   Author: Brouard
                    455: 
                    456:   In order to compile on Visual studio, time.h is now correct and time_t
                    457:   and tm struct should be used. difftime should be used but sometimes I
                    458:   just make the differences in raw time format (time(&now).
                    459:   Trying to suppress #ifdef LINUX
                    460:   Add xdg-open for __linux in order to open default browser.
                    461: 
1.157     brouard   462:   Revision 1.156  2014/08/25 20:10:10  brouard
                    463:   *** empty log message ***
                    464: 
1.156     brouard   465:   Revision 1.155  2014/08/25 18:32:34  brouard
                    466:   Summary: New compile, minor changes
                    467:   Author: Brouard
                    468: 
1.155     brouard   469:   Revision 1.154  2014/06/20 17:32:08  brouard
                    470:   Summary: Outputs now all graphs of convergence to period prevalence
                    471: 
1.154     brouard   472:   Revision 1.153  2014/06/20 16:45:46  brouard
                    473:   Summary: If 3 live state, convergence to period prevalence on same graph
                    474:   Author: Brouard
                    475: 
1.153     brouard   476:   Revision 1.152  2014/06/18 17:54:09  brouard
                    477:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    478: 
1.152     brouard   479:   Revision 1.151  2014/06/18 16:43:30  brouard
                    480:   *** empty log message ***
                    481: 
1.151     brouard   482:   Revision 1.150  2014/06/18 16:42:35  brouard
                    483:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    484:   Author: brouard
                    485: 
1.150     brouard   486:   Revision 1.149  2014/06/18 15:51:14  brouard
                    487:   Summary: Some fixes in parameter files errors
                    488:   Author: Nicolas Brouard
                    489: 
1.149     brouard   490:   Revision 1.148  2014/06/17 17:38:48  brouard
                    491:   Summary: Nothing new
                    492:   Author: Brouard
                    493: 
                    494:   Just a new packaging for OS/X version 0.98nS
                    495: 
1.148     brouard   496:   Revision 1.147  2014/06/16 10:33:11  brouard
                    497:   *** empty log message ***
                    498: 
1.147     brouard   499:   Revision 1.146  2014/06/16 10:20:28  brouard
                    500:   Summary: Merge
                    501:   Author: Brouard
                    502: 
                    503:   Merge, before building revised version.
                    504: 
1.146     brouard   505:   Revision 1.145  2014/06/10 21:23:15  brouard
                    506:   Summary: Debugging with valgrind
                    507:   Author: Nicolas Brouard
                    508: 
                    509:   Lot of changes in order to output the results with some covariates
                    510:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    511:   improve the code.
                    512:   No more memory valgrind error but a lot has to be done in order to
                    513:   continue the work of splitting the code into subroutines.
                    514:   Also, decodemodel has been improved. Tricode is still not
                    515:   optimal. nbcode should be improved. Documentation has been added in
                    516:   the source code.
                    517: 
1.144     brouard   518:   Revision 1.143  2014/01/26 09:45:38  brouard
                    519:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    520: 
                    521:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    522:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    523: 
1.143     brouard   524:   Revision 1.142  2014/01/26 03:57:36  brouard
                    525:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    526: 
                    527:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    528: 
1.142     brouard   529:   Revision 1.141  2014/01/26 02:42:01  brouard
                    530:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    531: 
1.141     brouard   532:   Revision 1.140  2011/09/02 10:37:54  brouard
                    533:   Summary: times.h is ok with mingw32 now.
                    534: 
1.140     brouard   535:   Revision 1.139  2010/06/14 07:50:17  brouard
                    536:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    537:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    538: 
1.139     brouard   539:   Revision 1.138  2010/04/30 18:19:40  brouard
                    540:   *** empty log message ***
                    541: 
1.138     brouard   542:   Revision 1.137  2010/04/29 18:11:38  brouard
                    543:   (Module): Checking covariates for more complex models
                    544:   than V1+V2. A lot of change to be done. Unstable.
                    545: 
1.137     brouard   546:   Revision 1.136  2010/04/26 20:30:53  brouard
                    547:   (Module): merging some libgsl code. Fixing computation
                    548:   of likelione (using inter/intrapolation if mle = 0) in order to
                    549:   get same likelihood as if mle=1.
                    550:   Some cleaning of code and comments added.
                    551: 
1.136     brouard   552:   Revision 1.135  2009/10/29 15:33:14  brouard
                    553:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    554: 
1.135     brouard   555:   Revision 1.134  2009/10/29 13:18:53  brouard
                    556:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    557: 
1.134     brouard   558:   Revision 1.133  2009/07/06 10:21:25  brouard
                    559:   just nforces
                    560: 
1.133     brouard   561:   Revision 1.132  2009/07/06 08:22:05  brouard
                    562:   Many tings
                    563: 
1.132     brouard   564:   Revision 1.131  2009/06/20 16:22:47  brouard
                    565:   Some dimensions resccaled
                    566: 
1.131     brouard   567:   Revision 1.130  2009/05/26 06:44:34  brouard
                    568:   (Module): Max Covariate is now set to 20 instead of 8. A
                    569:   lot of cleaning with variables initialized to 0. Trying to make
                    570:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    571: 
1.130     brouard   572:   Revision 1.129  2007/08/31 13:49:27  lievre
                    573:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    574: 
1.129     lievre    575:   Revision 1.128  2006/06/30 13:02:05  brouard
                    576:   (Module): Clarifications on computing e.j
                    577: 
1.128     brouard   578:   Revision 1.127  2006/04/28 18:11:50  brouard
                    579:   (Module): Yes the sum of survivors was wrong since
                    580:   imach-114 because nhstepm was no more computed in the age
                    581:   loop. Now we define nhstepma in the age loop.
                    582:   (Module): In order to speed up (in case of numerous covariates) we
                    583:   compute health expectancies (without variances) in a first step
                    584:   and then all the health expectancies with variances or standard
                    585:   deviation (needs data from the Hessian matrices) which slows the
                    586:   computation.
                    587:   In the future we should be able to stop the program is only health
                    588:   expectancies and graph are needed without standard deviations.
                    589: 
1.127     brouard   590:   Revision 1.126  2006/04/28 17:23:28  brouard
                    591:   (Module): Yes the sum of survivors was wrong since
                    592:   imach-114 because nhstepm was no more computed in the age
                    593:   loop. Now we define nhstepma in the age loop.
                    594:   Version 0.98h
                    595: 
1.126     brouard   596:   Revision 1.125  2006/04/04 15:20:31  lievre
                    597:   Errors in calculation of health expectancies. Age was not initialized.
                    598:   Forecasting file added.
                    599: 
                    600:   Revision 1.124  2006/03/22 17:13:53  lievre
                    601:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    602:   The log-likelihood is printed in the log file
                    603: 
                    604:   Revision 1.123  2006/03/20 10:52:43  brouard
                    605:   * imach.c (Module): <title> changed, corresponds to .htm file
                    606:   name. <head> headers where missing.
                    607: 
                    608:   * imach.c (Module): Weights can have a decimal point as for
                    609:   English (a comma might work with a correct LC_NUMERIC environment,
                    610:   otherwise the weight is truncated).
                    611:   Modification of warning when the covariates values are not 0 or
                    612:   1.
                    613:   Version 0.98g
                    614: 
                    615:   Revision 1.122  2006/03/20 09:45:41  brouard
                    616:   (Module): Weights can have a decimal point as for
                    617:   English (a comma might work with a correct LC_NUMERIC environment,
                    618:   otherwise the weight is truncated).
                    619:   Modification of warning when the covariates values are not 0 or
                    620:   1.
                    621:   Version 0.98g
                    622: 
                    623:   Revision 1.121  2006/03/16 17:45:01  lievre
                    624:   * imach.c (Module): Comments concerning covariates added
                    625: 
                    626:   * imach.c (Module): refinements in the computation of lli if
                    627:   status=-2 in order to have more reliable computation if stepm is
                    628:   not 1 month. Version 0.98f
                    629: 
                    630:   Revision 1.120  2006/03/16 15:10:38  lievre
                    631:   (Module): refinements in the computation of lli if
                    632:   status=-2 in order to have more reliable computation if stepm is
                    633:   not 1 month. Version 0.98f
                    634: 
                    635:   Revision 1.119  2006/03/15 17:42:26  brouard
                    636:   (Module): Bug if status = -2, the loglikelihood was
                    637:   computed as likelihood omitting the logarithm. Version O.98e
                    638: 
                    639:   Revision 1.118  2006/03/14 18:20:07  brouard
                    640:   (Module): varevsij Comments added explaining the second
                    641:   table of variances if popbased=1 .
                    642:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    643:   (Module): Function pstamp added
                    644:   (Module): Version 0.98d
                    645: 
                    646:   Revision 1.117  2006/03/14 17:16:22  brouard
                    647:   (Module): varevsij Comments added explaining the second
                    648:   table of variances if popbased=1 .
                    649:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    650:   (Module): Function pstamp added
                    651:   (Module): Version 0.98d
                    652: 
                    653:   Revision 1.116  2006/03/06 10:29:27  brouard
                    654:   (Module): Variance-covariance wrong links and
                    655:   varian-covariance of ej. is needed (Saito).
                    656: 
                    657:   Revision 1.115  2006/02/27 12:17:45  brouard
                    658:   (Module): One freematrix added in mlikeli! 0.98c
                    659: 
                    660:   Revision 1.114  2006/02/26 12:57:58  brouard
                    661:   (Module): Some improvements in processing parameter
                    662:   filename with strsep.
                    663: 
                    664:   Revision 1.113  2006/02/24 14:20:24  brouard
                    665:   (Module): Memory leaks checks with valgrind and:
                    666:   datafile was not closed, some imatrix were not freed and on matrix
                    667:   allocation too.
                    668: 
                    669:   Revision 1.112  2006/01/30 09:55:26  brouard
                    670:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    671: 
                    672:   Revision 1.111  2006/01/25 20:38:18  brouard
                    673:   (Module): Lots of cleaning and bugs added (Gompertz)
                    674:   (Module): Comments can be added in data file. Missing date values
                    675:   can be a simple dot '.'.
                    676: 
                    677:   Revision 1.110  2006/01/25 00:51:50  brouard
                    678:   (Module): Lots of cleaning and bugs added (Gompertz)
                    679: 
                    680:   Revision 1.109  2006/01/24 19:37:15  brouard
                    681:   (Module): Comments (lines starting with a #) are allowed in data.
                    682: 
                    683:   Revision 1.108  2006/01/19 18:05:42  lievre
                    684:   Gnuplot problem appeared...
                    685:   To be fixed
                    686: 
                    687:   Revision 1.107  2006/01/19 16:20:37  brouard
                    688:   Test existence of gnuplot in imach path
                    689: 
                    690:   Revision 1.106  2006/01/19 13:24:36  brouard
                    691:   Some cleaning and links added in html output
                    692: 
                    693:   Revision 1.105  2006/01/05 20:23:19  lievre
                    694:   *** empty log message ***
                    695: 
                    696:   Revision 1.104  2005/09/30 16:11:43  lievre
                    697:   (Module): sump fixed, loop imx fixed, and simplifications.
                    698:   (Module): If the status is missing at the last wave but we know
                    699:   that the person is alive, then we can code his/her status as -2
                    700:   (instead of missing=-1 in earlier versions) and his/her
                    701:   contributions to the likelihood is 1 - Prob of dying from last
                    702:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    703:   the healthy state at last known wave). Version is 0.98
                    704: 
                    705:   Revision 1.103  2005/09/30 15:54:49  lievre
                    706:   (Module): sump fixed, loop imx fixed, and simplifications.
                    707: 
                    708:   Revision 1.102  2004/09/15 17:31:30  brouard
                    709:   Add the possibility to read data file including tab characters.
                    710: 
                    711:   Revision 1.101  2004/09/15 10:38:38  brouard
                    712:   Fix on curr_time
                    713: 
                    714:   Revision 1.100  2004/07/12 18:29:06  brouard
                    715:   Add version for Mac OS X. Just define UNIX in Makefile
                    716: 
                    717:   Revision 1.99  2004/06/05 08:57:40  brouard
                    718:   *** empty log message ***
                    719: 
                    720:   Revision 1.98  2004/05/16 15:05:56  brouard
                    721:   New version 0.97 . First attempt to estimate force of mortality
                    722:   directly from the data i.e. without the need of knowing the health
                    723:   state at each age, but using a Gompertz model: log u =a + b*age .
                    724:   This is the basic analysis of mortality and should be done before any
                    725:   other analysis, in order to test if the mortality estimated from the
                    726:   cross-longitudinal survey is different from the mortality estimated
                    727:   from other sources like vital statistic data.
                    728: 
                    729:   The same imach parameter file can be used but the option for mle should be -3.
                    730: 
1.133     brouard   731:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   732:   former routines in order to include the new code within the former code.
                    733: 
                    734:   The output is very simple: only an estimate of the intercept and of
                    735:   the slope with 95% confident intervals.
                    736: 
                    737:   Current limitations:
                    738:   A) Even if you enter covariates, i.e. with the
                    739:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    740:   B) There is no computation of Life Expectancy nor Life Table.
                    741: 
                    742:   Revision 1.97  2004/02/20 13:25:42  lievre
                    743:   Version 0.96d. Population forecasting command line is (temporarily)
                    744:   suppressed.
                    745: 
                    746:   Revision 1.96  2003/07/15 15:38:55  brouard
                    747:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    748:   rewritten within the same printf. Workaround: many printfs.
                    749: 
                    750:   Revision 1.95  2003/07/08 07:54:34  brouard
                    751:   * imach.c (Repository):
                    752:   (Repository): Using imachwizard code to output a more meaningful covariance
                    753:   matrix (cov(a12,c31) instead of numbers.
                    754: 
                    755:   Revision 1.94  2003/06/27 13:00:02  brouard
                    756:   Just cleaning
                    757: 
                    758:   Revision 1.93  2003/06/25 16:33:55  brouard
                    759:   (Module): On windows (cygwin) function asctime_r doesn't
                    760:   exist so I changed back to asctime which exists.
                    761:   (Module): Version 0.96b
                    762: 
                    763:   Revision 1.92  2003/06/25 16:30:45  brouard
                    764:   (Module): On windows (cygwin) function asctime_r doesn't
                    765:   exist so I changed back to asctime which exists.
                    766: 
                    767:   Revision 1.91  2003/06/25 15:30:29  brouard
                    768:   * imach.c (Repository): Duplicated warning errors corrected.
                    769:   (Repository): Elapsed time after each iteration is now output. It
                    770:   helps to forecast when convergence will be reached. Elapsed time
                    771:   is stamped in powell.  We created a new html file for the graphs
                    772:   concerning matrix of covariance. It has extension -cov.htm.
                    773: 
                    774:   Revision 1.90  2003/06/24 12:34:15  brouard
                    775:   (Module): Some bugs corrected for windows. Also, when
                    776:   mle=-1 a template is output in file "or"mypar.txt with the design
                    777:   of the covariance matrix to be input.
                    778: 
                    779:   Revision 1.89  2003/06/24 12:30:52  brouard
                    780:   (Module): Some bugs corrected for windows. Also, when
                    781:   mle=-1 a template is output in file "or"mypar.txt with the design
                    782:   of the covariance matrix to be input.
                    783: 
                    784:   Revision 1.88  2003/06/23 17:54:56  brouard
                    785:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    786: 
                    787:   Revision 1.87  2003/06/18 12:26:01  brouard
                    788:   Version 0.96
                    789: 
                    790:   Revision 1.86  2003/06/17 20:04:08  brouard
                    791:   (Module): Change position of html and gnuplot routines and added
                    792:   routine fileappend.
                    793: 
                    794:   Revision 1.85  2003/06/17 13:12:43  brouard
                    795:   * imach.c (Repository): Check when date of death was earlier that
                    796:   current date of interview. It may happen when the death was just
                    797:   prior to the death. In this case, dh was negative and likelihood
                    798:   was wrong (infinity). We still send an "Error" but patch by
                    799:   assuming that the date of death was just one stepm after the
                    800:   interview.
                    801:   (Repository): Because some people have very long ID (first column)
                    802:   we changed int to long in num[] and we added a new lvector for
                    803:   memory allocation. But we also truncated to 8 characters (left
                    804:   truncation)
                    805:   (Repository): No more line truncation errors.
                    806: 
                    807:   Revision 1.84  2003/06/13 21:44:43  brouard
                    808:   * imach.c (Repository): Replace "freqsummary" at a correct
                    809:   place. It differs from routine "prevalence" which may be called
                    810:   many times. Probs is memory consuming and must be used with
                    811:   parcimony.
                    812:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    813: 
                    814:   Revision 1.83  2003/06/10 13:39:11  lievre
                    815:   *** empty log message ***
                    816: 
                    817:   Revision 1.82  2003/06/05 15:57:20  brouard
                    818:   Add log in  imach.c and  fullversion number is now printed.
                    819: 
                    820: */
                    821: /*
                    822:    Interpolated Markov Chain
                    823: 
                    824:   Short summary of the programme:
                    825:   
1.227     brouard   826:   This program computes Healthy Life Expectancies or State-specific
                    827:   (if states aren't health statuses) Expectancies from
                    828:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    829: 
                    830:   -1- a first survey ("cross") where individuals from different ages
                    831:   are interviewed on their health status or degree of disability (in
                    832:   the case of a health survey which is our main interest)
                    833: 
                    834:   -2- at least a second wave of interviews ("longitudinal") which
                    835:   measure each change (if any) in individual health status.  Health
                    836:   expectancies are computed from the time spent in each health state
                    837:   according to a model. More health states you consider, more time is
                    838:   necessary to reach the Maximum Likelihood of the parameters involved
                    839:   in the model.  The simplest model is the multinomial logistic model
                    840:   where pij is the probability to be observed in state j at the second
                    841:   wave conditional to be observed in state i at the first
                    842:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    843:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    844:   have a more complex model than "constant and age", you should modify
                    845:   the program where the markup *Covariates have to be included here
                    846:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   847:   convergence.
                    848: 
                    849:   The advantage of this computer programme, compared to a simple
                    850:   multinomial logistic model, is clear when the delay between waves is not
                    851:   identical for each individual. Also, if a individual missed an
                    852:   intermediate interview, the information is lost, but taken into
                    853:   account using an interpolation or extrapolation.  
                    854: 
                    855:   hPijx is the probability to be observed in state i at age x+h
                    856:   conditional to the observed state i at age x. The delay 'h' can be
                    857:   split into an exact number (nh*stepm) of unobserved intermediate
                    858:   states. This elementary transition (by month, quarter,
                    859:   semester or year) is modelled as a multinomial logistic.  The hPx
                    860:   matrix is simply the matrix product of nh*stepm elementary matrices
                    861:   and the contribution of each individual to the likelihood is simply
                    862:   hPijx.
                    863: 
                    864:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   865:   of the life expectancies. It also computes the period (stable) prevalence.
                    866: 
                    867: Back prevalence and projections:
1.227     brouard   868: 
                    869:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    870:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    871:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    872:    mobilavproj)
                    873: 
                    874:     Computes the back prevalence limit for any combination of
                    875:     covariate values k at any age between ageminpar and agemaxpar and
                    876:     returns it in **bprlim. In the loops,
                    877: 
                    878:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    879:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    880: 
                    881:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   882:    Computes for any combination of covariates k and any age between bage and fage 
                    883:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    884:                        oldm=oldms;savm=savms;
1.227     brouard   885: 
1.267     brouard   886:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   887:      Computes the transition matrix starting at age 'age' over
                    888:      'nhstepm*hstepm*stepm' months (i.e. until
                    889:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   890:      nhstepm*hstepm matrices. 
                    891: 
                    892:      Returns p3mat[i][j][h] after calling
                    893:      p3mat[i][j][h]=matprod2(newm,
                    894:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    895:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    896:      oldm);
1.226     brouard   897: 
                    898: Important routines
                    899: 
                    900: - func (or funcone), computes logit (pij) distinguishing
                    901:   o fixed variables (single or product dummies or quantitative);
                    902:   o varying variables by:
                    903:    (1) wave (single, product dummies, quantitative), 
                    904:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    905:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    906:        % varying dummy (not done) or quantitative (not done);
                    907: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    908:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    909: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    910:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    911:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   912: 
1.226     brouard   913: 
                    914:   
1.133     brouard   915:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    916:            Institut national d'études démographiques, Paris.
1.126     brouard   917:   This software have been partly granted by Euro-REVES, a concerted action
                    918:   from the European Union.
                    919:   It is copyrighted identically to a GNU software product, ie programme and
                    920:   software can be distributed freely for non commercial use. Latest version
                    921:   can be accessed at http://euroreves.ined.fr/imach .
                    922: 
                    923:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    924:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    925:   
                    926:   **********************************************************************/
                    927: /*
                    928:   main
                    929:   read parameterfile
                    930:   read datafile
                    931:   concatwav
                    932:   freqsummary
                    933:   if (mle >= 1)
                    934:     mlikeli
                    935:   print results files
                    936:   if mle==1 
                    937:      computes hessian
                    938:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    939:       begin-prev-date,...
                    940:   open gnuplot file
                    941:   open html file
1.145     brouard   942:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    943:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    944:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    945:     freexexit2 possible for memory heap.
                    946: 
                    947:   h Pij x                         | pij_nom  ficrestpij
                    948:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    949:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    950:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    951: 
                    952:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    953:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    954:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    955:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    956:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    957: 
1.126     brouard   958:   forecasting if prevfcast==1 prevforecast call prevalence()
                    959:   health expectancies
                    960:   Variance-covariance of DFLE
                    961:   prevalence()
                    962:    movingaverage()
                    963:   varevsij() 
                    964:   if popbased==1 varevsij(,popbased)
                    965:   total life expectancies
                    966:   Variance of period (stable) prevalence
                    967:  end
                    968: */
                    969: 
1.187     brouard   970: /* #define DEBUG */
                    971: /* #define DEBUGBRENT */
1.203     brouard   972: /* #define DEBUGLINMIN */
                    973: /* #define DEBUGHESS */
                    974: #define DEBUGHESSIJ
1.224     brouard   975: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   976: #define POWELL /* Instead of NLOPT */
1.224     brouard   977: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   978: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    979: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   980: 
                    981: #include <math.h>
                    982: #include <stdio.h>
                    983: #include <stdlib.h>
                    984: #include <string.h>
1.226     brouard   985: #include <ctype.h>
1.159     brouard   986: 
                    987: #ifdef _WIN32
                    988: #include <io.h>
1.172     brouard   989: #include <windows.h>
                    990: #include <tchar.h>
1.159     brouard   991: #else
1.126     brouard   992: #include <unistd.h>
1.159     brouard   993: #endif
1.126     brouard   994: 
                    995: #include <limits.h>
                    996: #include <sys/types.h>
1.171     brouard   997: 
                    998: #if defined(__GNUC__)
                    999: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1000: #endif
                   1001: 
1.126     brouard  1002: #include <sys/stat.h>
                   1003: #include <errno.h>
1.159     brouard  1004: /* extern int errno; */
1.126     brouard  1005: 
1.157     brouard  1006: /* #ifdef LINUX */
                   1007: /* #include <time.h> */
                   1008: /* #include "timeval.h" */
                   1009: /* #else */
                   1010: /* #include <sys/time.h> */
                   1011: /* #endif */
                   1012: 
1.126     brouard  1013: #include <time.h>
                   1014: 
1.136     brouard  1015: #ifdef GSL
                   1016: #include <gsl/gsl_errno.h>
                   1017: #include <gsl/gsl_multimin.h>
                   1018: #endif
                   1019: 
1.167     brouard  1020: 
1.162     brouard  1021: #ifdef NLOPT
                   1022: #include <nlopt.h>
                   1023: typedef struct {
                   1024:   double (* function)(double [] );
                   1025: } myfunc_data ;
                   1026: #endif
                   1027: 
1.126     brouard  1028: /* #include <libintl.h> */
                   1029: /* #define _(String) gettext (String) */
                   1030: 
1.251     brouard  1031: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1032: 
                   1033: #define GNUPLOTPROGRAM "gnuplot"
                   1034: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1035: #define FILENAMELENGTH 132
                   1036: 
                   1037: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1038: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1039: 
1.144     brouard  1040: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1041: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1042: 
                   1043: #define NINTERVMAX 8
1.144     brouard  1044: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1045: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                   1046: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1047: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1048: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1049: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1050: #define MAXN 20000
1.144     brouard  1051: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1052: /* #define AGESUP 130 */
1.288   ! brouard  1053: /* #define AGESUP 150 */
        !          1054: #define AGESUP 200
1.268     brouard  1055: #define AGEINF 0
1.218     brouard  1056: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1057: #define AGEBASE 40
1.194     brouard  1058: #define AGEOVERFLOW 1.e20
1.164     brouard  1059: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1060: #ifdef _WIN32
                   1061: #define DIRSEPARATOR '\\'
                   1062: #define CHARSEPARATOR "\\"
                   1063: #define ODIRSEPARATOR '/'
                   1064: #else
1.126     brouard  1065: #define DIRSEPARATOR '/'
                   1066: #define CHARSEPARATOR "/"
                   1067: #define ODIRSEPARATOR '\\'
                   1068: #endif
                   1069: 
1.288   ! brouard  1070: /* $Id: imach.c,v 1.287 2018/05/01 17:57:25 brouard Exp $ */
1.126     brouard  1071: /* $State: Exp $ */
1.196     brouard  1072: #include "version.h"
                   1073: char version[]=__IMACH_VERSION__;
1.283     brouard  1074: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.288   ! brouard  1075: char fullversion[]="$Revision: 1.287 $ $Date: 2018/05/01 17:57:25 $"; 
1.126     brouard  1076: char strstart[80];
                   1077: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1078: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1079: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1080: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1081: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1082: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1083: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1084: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1085: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1086: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1087: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1088: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1089: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1090: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1091: int nsd=0; /**< Total number of single dummy variables (output) */
                   1092: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1093: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1094: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1095: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1096: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1097: int cptcov=0; /* Working variable */
1.218     brouard  1098: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1099: int npar=NPARMAX;
                   1100: int nlstate=2; /* Number of live states */
                   1101: int ndeath=1; /* Number of dead states */
1.130     brouard  1102: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1103: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1104: int popbased=0;
                   1105: 
                   1106: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1107: int maxwav=0; /* Maxim number of waves */
                   1108: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1109: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1110: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1111:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1112: int mle=1, weightopt=0;
1.126     brouard  1113: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1114: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1115: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1116:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1117: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1118: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1119: 
1.130     brouard  1120: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1121: double **matprod2(); /* test */
1.126     brouard  1122: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1123: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1124: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1125: 
1.136     brouard  1126: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1127: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1128: FILE *ficlog, *ficrespow;
1.130     brouard  1129: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1130: double fretone; /* Only one call to likelihood */
1.130     brouard  1131: long ipmx=0; /* Number of contributions */
1.126     brouard  1132: double sw; /* Sum of weights */
                   1133: char filerespow[FILENAMELENGTH];
                   1134: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1135: FILE *ficresilk;
                   1136: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1137: FILE *ficresprobmorprev;
                   1138: FILE *fichtm, *fichtmcov; /* Html File */
                   1139: FILE *ficreseij;
                   1140: char filerese[FILENAMELENGTH];
                   1141: FILE *ficresstdeij;
                   1142: char fileresstde[FILENAMELENGTH];
                   1143: FILE *ficrescveij;
                   1144: char filerescve[FILENAMELENGTH];
                   1145: FILE  *ficresvij;
                   1146: char fileresv[FILENAMELENGTH];
1.269     brouard  1147: 
1.126     brouard  1148: char title[MAXLINE];
1.234     brouard  1149: char model[MAXLINE]; /**< The model line */
1.217     brouard  1150: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1151: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1152: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1153: char command[FILENAMELENGTH];
                   1154: int  outcmd=0;
                   1155: 
1.217     brouard  1156: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1157: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1158: char filelog[FILENAMELENGTH]; /* Log file */
                   1159: char filerest[FILENAMELENGTH];
                   1160: char fileregp[FILENAMELENGTH];
                   1161: char popfile[FILENAMELENGTH];
                   1162: 
                   1163: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1164: 
1.157     brouard  1165: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1166: /* struct timezone tzp; */
                   1167: /* extern int gettimeofday(); */
                   1168: struct tm tml, *gmtime(), *localtime();
                   1169: 
                   1170: extern time_t time();
                   1171: 
                   1172: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1173: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1174: struct tm tm;
                   1175: 
1.126     brouard  1176: char strcurr[80], strfor[80];
                   1177: 
                   1178: char *endptr;
                   1179: long lval;
                   1180: double dval;
                   1181: 
                   1182: #define NR_END 1
                   1183: #define FREE_ARG char*
                   1184: #define FTOL 1.0e-10
                   1185: 
                   1186: #define NRANSI 
1.240     brouard  1187: #define ITMAX 200
                   1188: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1189: 
                   1190: #define TOL 2.0e-4 
                   1191: 
                   1192: #define CGOLD 0.3819660 
                   1193: #define ZEPS 1.0e-10 
                   1194: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1195: 
                   1196: #define GOLD 1.618034 
                   1197: #define GLIMIT 100.0 
                   1198: #define TINY 1.0e-20 
                   1199: 
                   1200: static double maxarg1,maxarg2;
                   1201: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1202: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1203:   
                   1204: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1205: #define rint(a) floor(a+0.5)
1.166     brouard  1206: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1207: #define mytinydouble 1.0e-16
1.166     brouard  1208: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1209: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1210: /* static double dsqrarg; */
                   1211: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1212: static double sqrarg;
                   1213: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1214: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1215: int agegomp= AGEGOMP;
                   1216: 
                   1217: int imx; 
                   1218: int stepm=1;
                   1219: /* Stepm, step in month: minimum step interpolation*/
                   1220: 
                   1221: int estepm;
                   1222: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1223: 
                   1224: int m,nb;
                   1225: long *num;
1.197     brouard  1226: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1227: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1228:                   covariate for which somebody answered excluding 
                   1229:                   undefined. Usually 2: 0 and 1. */
                   1230: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1231:                             covariate for which somebody answered including 
                   1232:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1233: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1234: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1235: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1236: double *ageexmed,*agecens;
                   1237: double dateintmean=0;
                   1238: 
                   1239: double *weight;
                   1240: int **s; /* Status */
1.141     brouard  1241: double *agedc;
1.145     brouard  1242: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1243:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1244:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1245: double **coqvar; /* Fixed quantitative covariate nqv */
                   1246: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1247: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1248: double  idx; 
                   1249: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1250: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1251: /*k          1  2   3   4     5    6    7     8    9 */
                   1252: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1253: /* Tndvar[k]    1   2   3               4          5 */
                   1254: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1255: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1256: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1257: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1258: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1259: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1260: /* Tprod[i]=k           4               7            */
                   1261: /* Tage[i]=k                  5               8      */
                   1262: /* */
                   1263: /* Type                    */
                   1264: /* V         1  2  3  4  5 */
                   1265: /*           F  F  V  V  V */
                   1266: /*           D  Q  D  D  Q */
                   1267: /*                         */
                   1268: int *TvarsD;
                   1269: int *TvarsDind;
                   1270: int *TvarsQ;
                   1271: int *TvarsQind;
                   1272: 
1.235     brouard  1273: #define MAXRESULTLINES 10
                   1274: int nresult=0;
1.258     brouard  1275: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1276: int TKresult[MAXRESULTLINES];
1.237     brouard  1277: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1278: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1279: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1280: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1281: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1282: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1283: 
1.234     brouard  1284: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1285: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1286: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1287: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1288: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1289: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1290: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1291: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1292: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1293: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1294: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1295: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1296: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1297: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1298: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1299: 
1.230     brouard  1300: int *Tvarsel; /**< Selected covariates for output */
                   1301: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1302: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1303: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1304: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1305: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1306: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1307: int *Tage;
1.227     brouard  1308: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1309: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1310: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1311: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1312: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1313: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1314: int **Tvard;
                   1315: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1316: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1317: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1318:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1319:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1320: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1321: double *lsurv, *lpop, *tpop;
                   1322: 
1.231     brouard  1323: #define FD 1; /* Fixed dummy covariate */
                   1324: #define FQ 2; /* Fixed quantitative covariate */
                   1325: #define FP 3; /* Fixed product covariate */
                   1326: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1327: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1328: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1329: #define VD 10; /* Varying dummy covariate */
                   1330: #define VQ 11; /* Varying quantitative covariate */
                   1331: #define VP 12; /* Varying product covariate */
                   1332: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1333: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1334: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1335: #define APFD 16; /* Age product * fixed dummy covariate */
                   1336: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1337: #define APVD 18; /* Age product * varying dummy covariate */
                   1338: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1339: 
                   1340: #define FTYPE 1; /* Fixed covariate */
                   1341: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1342: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1343: 
                   1344: struct kmodel{
                   1345:        int maintype; /* main type */
                   1346:        int subtype; /* subtype */
                   1347: };
                   1348: struct kmodel modell[NCOVMAX];
                   1349: 
1.143     brouard  1350: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1351: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1352: 
                   1353: /**************** split *************************/
                   1354: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1355: {
                   1356:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1357:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1358:   */ 
                   1359:   char *ss;                            /* pointer */
1.186     brouard  1360:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1361: 
                   1362:   l1 = strlen(path );                  /* length of path */
                   1363:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1364:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1365:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1366:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1367:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1368:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1369:     /* get current working directory */
                   1370:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1371: #ifdef WIN32
                   1372:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1373: #else
                   1374:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1375: #endif
1.126     brouard  1376:       return( GLOCK_ERROR_GETCWD );
                   1377:     }
                   1378:     /* got dirc from getcwd*/
                   1379:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1380:   } else {                             /* strip directory from path */
1.126     brouard  1381:     ss++;                              /* after this, the filename */
                   1382:     l2 = strlen( ss );                 /* length of filename */
                   1383:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1384:     strcpy( name, ss );                /* save file name */
                   1385:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1386:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1387:     printf(" DIRC2 = %s \n",dirc);
                   1388:   }
                   1389:   /* We add a separator at the end of dirc if not exists */
                   1390:   l1 = strlen( dirc );                 /* length of directory */
                   1391:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1392:     dirc[l1] =  DIRSEPARATOR;
                   1393:     dirc[l1+1] = 0; 
                   1394:     printf(" DIRC3 = %s \n",dirc);
                   1395:   }
                   1396:   ss = strrchr( name, '.' );           /* find last / */
                   1397:   if (ss >0){
                   1398:     ss++;
                   1399:     strcpy(ext,ss);                    /* save extension */
                   1400:     l1= strlen( name);
                   1401:     l2= strlen(ss)+1;
                   1402:     strncpy( finame, name, l1-l2);
                   1403:     finame[l1-l2]= 0;
                   1404:   }
                   1405: 
                   1406:   return( 0 );                         /* we're done */
                   1407: }
                   1408: 
                   1409: 
                   1410: /******************************************/
                   1411: 
                   1412: void replace_back_to_slash(char *s, char*t)
                   1413: {
                   1414:   int i;
                   1415:   int lg=0;
                   1416:   i=0;
                   1417:   lg=strlen(t);
                   1418:   for(i=0; i<= lg; i++) {
                   1419:     (s[i] = t[i]);
                   1420:     if (t[i]== '\\') s[i]='/';
                   1421:   }
                   1422: }
                   1423: 
1.132     brouard  1424: char *trimbb(char *out, char *in)
1.137     brouard  1425: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1426:   char *s;
                   1427:   s=out;
                   1428:   while (*in != '\0'){
1.137     brouard  1429:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1430:       in++;
                   1431:     }
                   1432:     *out++ = *in++;
                   1433:   }
                   1434:   *out='\0';
                   1435:   return s;
                   1436: }
                   1437: 
1.187     brouard  1438: /* char *substrchaine(char *out, char *in, char *chain) */
                   1439: /* { */
                   1440: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1441: /*   char *s, *t; */
                   1442: /*   t=in;s=out; */
                   1443: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1444: /*     *out++ = *in++; */
                   1445: /*   } */
                   1446: 
                   1447: /*   /\* *in matches *chain *\/ */
                   1448: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1449: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1450: /*   } */
                   1451: /*   in--; chain--; */
                   1452: /*   while ( (*in != '\0')){ */
                   1453: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1454: /*     *out++ = *in++; */
                   1455: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1456: /*   } */
                   1457: /*   *out='\0'; */
                   1458: /*   out=s; */
                   1459: /*   return out; */
                   1460: /* } */
                   1461: char *substrchaine(char *out, char *in, char *chain)
                   1462: {
                   1463:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1464:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1465: 
                   1466:   char *strloc;
                   1467: 
                   1468:   strcpy (out, in); 
                   1469:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1470:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1471:   if(strloc != NULL){ 
                   1472:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1473:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1474:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1475:   }
                   1476:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1477:   return out;
                   1478: }
                   1479: 
                   1480: 
1.145     brouard  1481: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1482: {
1.187     brouard  1483:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1484:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1485:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1486:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1487:   */
1.160     brouard  1488:   char *s, *t;
1.145     brouard  1489:   t=in;s=in;
                   1490:   while ((*in != occ) && (*in != '\0')){
                   1491:     *alocc++ = *in++;
                   1492:   }
                   1493:   if( *in == occ){
                   1494:     *(alocc)='\0';
                   1495:     s=++in;
                   1496:   }
                   1497:  
                   1498:   if (s == t) {/* occ not found */
                   1499:     *(alocc-(in-s))='\0';
                   1500:     in=s;
                   1501:   }
                   1502:   while ( *in != '\0'){
                   1503:     *blocc++ = *in++;
                   1504:   }
                   1505: 
                   1506:   *blocc='\0';
                   1507:   return t;
                   1508: }
1.137     brouard  1509: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1510: {
1.187     brouard  1511:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1512:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1513:      gives blocc="abcdef2ghi" and alocc="j".
                   1514:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1515:   */
                   1516:   char *s, *t;
                   1517:   t=in;s=in;
                   1518:   while (*in != '\0'){
                   1519:     while( *in == occ){
                   1520:       *blocc++ = *in++;
                   1521:       s=in;
                   1522:     }
                   1523:     *blocc++ = *in++;
                   1524:   }
                   1525:   if (s == t) /* occ not found */
                   1526:     *(blocc-(in-s))='\0';
                   1527:   else
                   1528:     *(blocc-(in-s)-1)='\0';
                   1529:   in=s;
                   1530:   while ( *in != '\0'){
                   1531:     *alocc++ = *in++;
                   1532:   }
                   1533: 
                   1534:   *alocc='\0';
                   1535:   return s;
                   1536: }
                   1537: 
1.126     brouard  1538: int nbocc(char *s, char occ)
                   1539: {
                   1540:   int i,j=0;
                   1541:   int lg=20;
                   1542:   i=0;
                   1543:   lg=strlen(s);
                   1544:   for(i=0; i<= lg; i++) {
1.234     brouard  1545:     if  (s[i] == occ ) j++;
1.126     brouard  1546:   }
                   1547:   return j;
                   1548: }
                   1549: 
1.137     brouard  1550: /* void cutv(char *u,char *v, char*t, char occ) */
                   1551: /* { */
                   1552: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1553: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1554: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1555: /*   int i,lg,j,p=0; */
                   1556: /*   i=0; */
                   1557: /*   lg=strlen(t); */
                   1558: /*   for(j=0; j<=lg-1; j++) { */
                   1559: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1560: /*   } */
1.126     brouard  1561: 
1.137     brouard  1562: /*   for(j=0; j<p; j++) { */
                   1563: /*     (u[j] = t[j]); */
                   1564: /*   } */
                   1565: /*      u[p]='\0'; */
1.126     brouard  1566: 
1.137     brouard  1567: /*    for(j=0; j<= lg; j++) { */
                   1568: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1569: /*   } */
                   1570: /* } */
1.126     brouard  1571: 
1.160     brouard  1572: #ifdef _WIN32
                   1573: char * strsep(char **pp, const char *delim)
                   1574: {
                   1575:   char *p, *q;
                   1576:          
                   1577:   if ((p = *pp) == NULL)
                   1578:     return 0;
                   1579:   if ((q = strpbrk (p, delim)) != NULL)
                   1580:   {
                   1581:     *pp = q + 1;
                   1582:     *q = '\0';
                   1583:   }
                   1584:   else
                   1585:     *pp = 0;
                   1586:   return p;
                   1587: }
                   1588: #endif
                   1589: 
1.126     brouard  1590: /********************** nrerror ********************/
                   1591: 
                   1592: void nrerror(char error_text[])
                   1593: {
                   1594:   fprintf(stderr,"ERREUR ...\n");
                   1595:   fprintf(stderr,"%s\n",error_text);
                   1596:   exit(EXIT_FAILURE);
                   1597: }
                   1598: /*********************** vector *******************/
                   1599: double *vector(int nl, int nh)
                   1600: {
                   1601:   double *v;
                   1602:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1603:   if (!v) nrerror("allocation failure in vector");
                   1604:   return v-nl+NR_END;
                   1605: }
                   1606: 
                   1607: /************************ free vector ******************/
                   1608: void free_vector(double*v, int nl, int nh)
                   1609: {
                   1610:   free((FREE_ARG)(v+nl-NR_END));
                   1611: }
                   1612: 
                   1613: /************************ivector *******************************/
                   1614: int *ivector(long nl,long nh)
                   1615: {
                   1616:   int *v;
                   1617:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1618:   if (!v) nrerror("allocation failure in ivector");
                   1619:   return v-nl+NR_END;
                   1620: }
                   1621: 
                   1622: /******************free ivector **************************/
                   1623: void free_ivector(int *v, long nl, long nh)
                   1624: {
                   1625:   free((FREE_ARG)(v+nl-NR_END));
                   1626: }
                   1627: 
                   1628: /************************lvector *******************************/
                   1629: long *lvector(long nl,long nh)
                   1630: {
                   1631:   long *v;
                   1632:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1633:   if (!v) nrerror("allocation failure in ivector");
                   1634:   return v-nl+NR_END;
                   1635: }
                   1636: 
                   1637: /******************free lvector **************************/
                   1638: void free_lvector(long *v, long nl, long nh)
                   1639: {
                   1640:   free((FREE_ARG)(v+nl-NR_END));
                   1641: }
                   1642: 
                   1643: /******************* imatrix *******************************/
                   1644: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1645:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1646: { 
                   1647:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1648:   int **m; 
                   1649:   
                   1650:   /* allocate pointers to rows */ 
                   1651:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1652:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1653:   m += NR_END; 
                   1654:   m -= nrl; 
                   1655:   
                   1656:   
                   1657:   /* allocate rows and set pointers to them */ 
                   1658:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1659:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1660:   m[nrl] += NR_END; 
                   1661:   m[nrl] -= ncl; 
                   1662:   
                   1663:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1664:   
                   1665:   /* return pointer to array of pointers to rows */ 
                   1666:   return m; 
                   1667: } 
                   1668: 
                   1669: /****************** free_imatrix *************************/
                   1670: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1671:       int **m;
                   1672:       long nch,ncl,nrh,nrl; 
                   1673:      /* free an int matrix allocated by imatrix() */ 
                   1674: { 
                   1675:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1676:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1677: } 
                   1678: 
                   1679: /******************* matrix *******************************/
                   1680: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1681: {
                   1682:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1683:   double **m;
                   1684: 
                   1685:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1686:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1687:   m += NR_END;
                   1688:   m -= nrl;
                   1689: 
                   1690:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1691:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1692:   m[nrl] += NR_END;
                   1693:   m[nrl] -= ncl;
                   1694: 
                   1695:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1696:   return m;
1.145     brouard  1697:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1698: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1699: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1700:    */
                   1701: }
                   1702: 
                   1703: /*************************free matrix ************************/
                   1704: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1705: {
                   1706:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1707:   free((FREE_ARG)(m+nrl-NR_END));
                   1708: }
                   1709: 
                   1710: /******************* ma3x *******************************/
                   1711: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1712: {
                   1713:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1714:   double ***m;
                   1715: 
                   1716:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1717:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1718:   m += NR_END;
                   1719:   m -= nrl;
                   1720: 
                   1721:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1722:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1723:   m[nrl] += NR_END;
                   1724:   m[nrl] -= ncl;
                   1725: 
                   1726:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1727: 
                   1728:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1729:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1730:   m[nrl][ncl] += NR_END;
                   1731:   m[nrl][ncl] -= nll;
                   1732:   for (j=ncl+1; j<=nch; j++) 
                   1733:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1734:   
                   1735:   for (i=nrl+1; i<=nrh; i++) {
                   1736:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1737:     for (j=ncl+1; j<=nch; j++) 
                   1738:       m[i][j]=m[i][j-1]+nlay;
                   1739:   }
                   1740:   return m; 
                   1741:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1742:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1743:   */
                   1744: }
                   1745: 
                   1746: /*************************free ma3x ************************/
                   1747: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1748: {
                   1749:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1750:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1751:   free((FREE_ARG)(m+nrl-NR_END));
                   1752: }
                   1753: 
                   1754: /*************** function subdirf ***********/
                   1755: char *subdirf(char fileres[])
                   1756: {
                   1757:   /* Caution optionfilefiname is hidden */
                   1758:   strcpy(tmpout,optionfilefiname);
                   1759:   strcat(tmpout,"/"); /* Add to the right */
                   1760:   strcat(tmpout,fileres);
                   1761:   return tmpout;
                   1762: }
                   1763: 
                   1764: /*************** function subdirf2 ***********/
                   1765: char *subdirf2(char fileres[], char *preop)
                   1766: {
                   1767:   
                   1768:   /* Caution optionfilefiname is hidden */
                   1769:   strcpy(tmpout,optionfilefiname);
                   1770:   strcat(tmpout,"/");
                   1771:   strcat(tmpout,preop);
                   1772:   strcat(tmpout,fileres);
                   1773:   return tmpout;
                   1774: }
                   1775: 
                   1776: /*************** function subdirf3 ***********/
                   1777: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1778: {
                   1779:   
                   1780:   /* Caution optionfilefiname is hidden */
                   1781:   strcpy(tmpout,optionfilefiname);
                   1782:   strcat(tmpout,"/");
                   1783:   strcat(tmpout,preop);
                   1784:   strcat(tmpout,preop2);
                   1785:   strcat(tmpout,fileres);
                   1786:   return tmpout;
                   1787: }
1.213     brouard  1788:  
                   1789: /*************** function subdirfext ***********/
                   1790: char *subdirfext(char fileres[], char *preop, char *postop)
                   1791: {
                   1792:   
                   1793:   strcpy(tmpout,preop);
                   1794:   strcat(tmpout,fileres);
                   1795:   strcat(tmpout,postop);
                   1796:   return tmpout;
                   1797: }
1.126     brouard  1798: 
1.213     brouard  1799: /*************** function subdirfext3 ***********/
                   1800: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1801: {
                   1802:   
                   1803:   /* Caution optionfilefiname is hidden */
                   1804:   strcpy(tmpout,optionfilefiname);
                   1805:   strcat(tmpout,"/");
                   1806:   strcat(tmpout,preop);
                   1807:   strcat(tmpout,fileres);
                   1808:   strcat(tmpout,postop);
                   1809:   return tmpout;
                   1810: }
                   1811:  
1.162     brouard  1812: char *asc_diff_time(long time_sec, char ascdiff[])
                   1813: {
                   1814:   long sec_left, days, hours, minutes;
                   1815:   days = (time_sec) / (60*60*24);
                   1816:   sec_left = (time_sec) % (60*60*24);
                   1817:   hours = (sec_left) / (60*60) ;
                   1818:   sec_left = (sec_left) %(60*60);
                   1819:   minutes = (sec_left) /60;
                   1820:   sec_left = (sec_left) % (60);
                   1821:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1822:   return ascdiff;
                   1823: }
                   1824: 
1.126     brouard  1825: /***************** f1dim *************************/
                   1826: extern int ncom; 
                   1827: extern double *pcom,*xicom;
                   1828: extern double (*nrfunc)(double []); 
                   1829:  
                   1830: double f1dim(double x) 
                   1831: { 
                   1832:   int j; 
                   1833:   double f;
                   1834:   double *xt; 
                   1835:  
                   1836:   xt=vector(1,ncom); 
                   1837:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1838:   f=(*nrfunc)(xt); 
                   1839:   free_vector(xt,1,ncom); 
                   1840:   return f; 
                   1841: } 
                   1842: 
                   1843: /*****************brent *************************/
                   1844: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1845: {
                   1846:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1847:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1848:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1849:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1850:    * returned function value. 
                   1851:   */
1.126     brouard  1852:   int iter; 
                   1853:   double a,b,d,etemp;
1.159     brouard  1854:   double fu=0,fv,fw,fx;
1.164     brouard  1855:   double ftemp=0.;
1.126     brouard  1856:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1857:   double e=0.0; 
                   1858:  
                   1859:   a=(ax < cx ? ax : cx); 
                   1860:   b=(ax > cx ? ax : cx); 
                   1861:   x=w=v=bx; 
                   1862:   fw=fv=fx=(*f)(x); 
                   1863:   for (iter=1;iter<=ITMAX;iter++) { 
                   1864:     xm=0.5*(a+b); 
                   1865:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1866:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1867:     printf(".");fflush(stdout);
                   1868:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1869: #ifdef DEBUGBRENT
1.126     brouard  1870:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1871:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1872:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1873: #endif
                   1874:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1875:       *xmin=x; 
                   1876:       return fx; 
                   1877:     } 
                   1878:     ftemp=fu;
                   1879:     if (fabs(e) > tol1) { 
                   1880:       r=(x-w)*(fx-fv); 
                   1881:       q=(x-v)*(fx-fw); 
                   1882:       p=(x-v)*q-(x-w)*r; 
                   1883:       q=2.0*(q-r); 
                   1884:       if (q > 0.0) p = -p; 
                   1885:       q=fabs(q); 
                   1886:       etemp=e; 
                   1887:       e=d; 
                   1888:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1889:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1890:       else { 
1.224     brouard  1891:                                d=p/q; 
                   1892:                                u=x+d; 
                   1893:                                if (u-a < tol2 || b-u < tol2) 
                   1894:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1895:       } 
                   1896:     } else { 
                   1897:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1898:     } 
                   1899:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1900:     fu=(*f)(u); 
                   1901:     if (fu <= fx) { 
                   1902:       if (u >= x) a=x; else b=x; 
                   1903:       SHFT(v,w,x,u) 
1.183     brouard  1904:       SHFT(fv,fw,fx,fu) 
                   1905:     } else { 
                   1906:       if (u < x) a=u; else b=u; 
                   1907:       if (fu <= fw || w == x) { 
1.224     brouard  1908:                                v=w; 
                   1909:                                w=u; 
                   1910:                                fv=fw; 
                   1911:                                fw=fu; 
1.183     brouard  1912:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1913:                                v=u; 
                   1914:                                fv=fu; 
1.183     brouard  1915:       } 
                   1916:     } 
1.126     brouard  1917:   } 
                   1918:   nrerror("Too many iterations in brent"); 
                   1919:   *xmin=x; 
                   1920:   return fx; 
                   1921: } 
                   1922: 
                   1923: /****************** mnbrak ***********************/
                   1924: 
                   1925: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1926:            double (*func)(double)) 
1.183     brouard  1927: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1928: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1929: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1930: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1931:    */
1.126     brouard  1932:   double ulim,u,r,q, dum;
                   1933:   double fu; 
1.187     brouard  1934: 
                   1935:   double scale=10.;
                   1936:   int iterscale=0;
                   1937: 
                   1938:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1939:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1940: 
                   1941: 
                   1942:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1943:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1944:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1945:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1946:   /* } */
                   1947: 
1.126     brouard  1948:   if (*fb > *fa) { 
                   1949:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1950:     SHFT(dum,*fb,*fa,dum) 
                   1951:   } 
1.126     brouard  1952:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1953:   *fc=(*func)(*cx); 
1.183     brouard  1954: #ifdef DEBUG
1.224     brouard  1955:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1956:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1957: #endif
1.224     brouard  1958:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1959:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1960:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1961:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1962:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1963:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1964:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1965:       fu=(*func)(u); 
1.163     brouard  1966: #ifdef DEBUG
                   1967:       /* f(x)=A(x-u)**2+f(u) */
                   1968:       double A, fparabu; 
                   1969:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1970:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1971:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1972:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1973:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1974:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1975:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1976:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1977: #endif 
1.184     brouard  1978: #ifdef MNBRAKORIGINAL
1.183     brouard  1979: #else
1.191     brouard  1980: /*       if (fu > *fc) { */
                   1981: /* #ifdef DEBUG */
                   1982: /*       printf("mnbrak4  fu > fc \n"); */
                   1983: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1984: /* #endif */
                   1985: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1986: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1987: /*     dum=u; /\* Shifting c and u *\/ */
                   1988: /*     u = *cx; */
                   1989: /*     *cx = dum; */
                   1990: /*     dum = fu; */
                   1991: /*     fu = *fc; */
                   1992: /*     *fc =dum; */
                   1993: /*       } else { /\* end *\/ */
                   1994: /* #ifdef DEBUG */
                   1995: /*       printf("mnbrak3  fu < fc \n"); */
                   1996: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   1997: /* #endif */
                   1998: /*     dum=u; /\* Shifting c and u *\/ */
                   1999: /*     u = *cx; */
                   2000: /*     *cx = dum; */
                   2001: /*     dum = fu; */
                   2002: /*     fu = *fc; */
                   2003: /*     *fc =dum; */
                   2004: /*       } */
1.224     brouard  2005: #ifdef DEBUGMNBRAK
                   2006:                 double A, fparabu; 
                   2007:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2008:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2009:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2010:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2011: #endif
1.191     brouard  2012:       dum=u; /* Shifting c and u */
                   2013:       u = *cx;
                   2014:       *cx = dum;
                   2015:       dum = fu;
                   2016:       fu = *fc;
                   2017:       *fc =dum;
1.183     brouard  2018: #endif
1.162     brouard  2019:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2020: #ifdef DEBUG
1.224     brouard  2021:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2022:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2023: #endif
1.126     brouard  2024:       fu=(*func)(u); 
                   2025:       if (fu < *fc) { 
1.183     brouard  2026: #ifdef DEBUG
1.224     brouard  2027:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2028:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2029: #endif
                   2030:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2031:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2032: #ifdef DEBUG
                   2033:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2034: #endif
                   2035:       } 
1.162     brouard  2036:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2037: #ifdef DEBUG
1.224     brouard  2038:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2039:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2040: #endif
1.126     brouard  2041:       u=ulim; 
                   2042:       fu=(*func)(u); 
1.183     brouard  2043:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2044: #ifdef DEBUG
1.224     brouard  2045:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2046:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2047: #endif
1.126     brouard  2048:       u=(*cx)+GOLD*(*cx-*bx); 
                   2049:       fu=(*func)(u); 
1.224     brouard  2050: #ifdef DEBUG
                   2051:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2052:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2053: #endif
1.183     brouard  2054:     } /* end tests */
1.126     brouard  2055:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2056:     SHFT(*fa,*fb,*fc,fu) 
                   2057: #ifdef DEBUG
1.224     brouard  2058:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2059:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2060: #endif
                   2061:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2062: } 
                   2063: 
                   2064: /*************** linmin ************************/
1.162     brouard  2065: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2066: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2067: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2068: the value of func at the returned location p . This is actually all accomplished by calling the
                   2069: routines mnbrak and brent .*/
1.126     brouard  2070: int ncom; 
                   2071: double *pcom,*xicom;
                   2072: double (*nrfunc)(double []); 
                   2073:  
1.224     brouard  2074: #ifdef LINMINORIGINAL
1.126     brouard  2075: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2076: #else
                   2077: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2078: #endif
1.126     brouard  2079: { 
                   2080:   double brent(double ax, double bx, double cx, 
                   2081:               double (*f)(double), double tol, double *xmin); 
                   2082:   double f1dim(double x); 
                   2083:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2084:              double *fc, double (*func)(double)); 
                   2085:   int j; 
                   2086:   double xx,xmin,bx,ax; 
                   2087:   double fx,fb,fa;
1.187     brouard  2088: 
1.203     brouard  2089: #ifdef LINMINORIGINAL
                   2090: #else
                   2091:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2092: #endif
                   2093:   
1.126     brouard  2094:   ncom=n; 
                   2095:   pcom=vector(1,n); 
                   2096:   xicom=vector(1,n); 
                   2097:   nrfunc=func; 
                   2098:   for (j=1;j<=n;j++) { 
                   2099:     pcom[j]=p[j]; 
1.202     brouard  2100:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2101:   } 
1.187     brouard  2102: 
1.203     brouard  2103: #ifdef LINMINORIGINAL
                   2104:   xx=1.;
                   2105: #else
                   2106:   axs=0.0;
                   2107:   xxs=1.;
                   2108:   do{
                   2109:     xx= xxs;
                   2110: #endif
1.187     brouard  2111:     ax=0.;
                   2112:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2113:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2114:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2115:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2116:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2117:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2118:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2119: #ifdef LINMINORIGINAL
                   2120: #else
                   2121:     if (fx != fx){
1.224     brouard  2122:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2123:                        printf("|");
                   2124:                        fprintf(ficlog,"|");
1.203     brouard  2125: #ifdef DEBUGLINMIN
1.224     brouard  2126:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2127: #endif
                   2128:     }
1.224     brouard  2129:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2130: #endif
                   2131:   
1.191     brouard  2132: #ifdef DEBUGLINMIN
                   2133:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2134:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2135: #endif
1.224     brouard  2136: #ifdef LINMINORIGINAL
                   2137: #else
                   2138:        if(fb == fx){ /* Flat function in the direction */
                   2139:                xmin=xx;
                   2140:     *flat=1;
                   2141:        }else{
                   2142:     *flat=0;
                   2143: #endif
                   2144:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2145:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2146:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2147:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2148:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2149:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2150: #ifdef DEBUG
1.224     brouard  2151:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2152:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2153: #endif
                   2154: #ifdef LINMINORIGINAL
                   2155: #else
                   2156:                        }
1.126     brouard  2157: #endif
1.191     brouard  2158: #ifdef DEBUGLINMIN
                   2159:   printf("linmin end ");
1.202     brouard  2160:   fprintf(ficlog,"linmin end ");
1.191     brouard  2161: #endif
1.126     brouard  2162:   for (j=1;j<=n;j++) { 
1.203     brouard  2163: #ifdef LINMINORIGINAL
                   2164:     xi[j] *= xmin; 
                   2165: #else
                   2166: #ifdef DEBUGLINMIN
                   2167:     if(xxs <1.0)
                   2168:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2169: #endif
                   2170:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2171: #ifdef DEBUGLINMIN
                   2172:     if(xxs <1.0)
                   2173:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2174: #endif
                   2175: #endif
1.187     brouard  2176:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2177:   } 
1.191     brouard  2178: #ifdef DEBUGLINMIN
1.203     brouard  2179:   printf("\n");
1.191     brouard  2180:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2181:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2182:   for (j=1;j<=n;j++) { 
1.202     brouard  2183:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2184:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2185:     if(j % ncovmodel == 0){
1.191     brouard  2186:       printf("\n");
1.202     brouard  2187:       fprintf(ficlog,"\n");
                   2188:     }
1.191     brouard  2189:   }
1.203     brouard  2190: #else
1.191     brouard  2191: #endif
1.126     brouard  2192:   free_vector(xicom,1,n); 
                   2193:   free_vector(pcom,1,n); 
                   2194: } 
                   2195: 
                   2196: 
                   2197: /*************** powell ************************/
1.162     brouard  2198: /*
                   2199: Minimization of a function func of n variables. Input consists of an initial starting point
                   2200: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2201: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2202: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2203: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2204: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2205:  */
1.224     brouard  2206: #ifdef LINMINORIGINAL
                   2207: #else
                   2208:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2209:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2210: #endif
1.126     brouard  2211: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2212:            double (*func)(double [])) 
                   2213: { 
1.224     brouard  2214: #ifdef LINMINORIGINAL
                   2215:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2216:              double (*func)(double [])); 
1.224     brouard  2217: #else 
1.241     brouard  2218:  void linmin(double p[], double xi[], int n, double *fret,
                   2219:             double (*func)(double []),int *flat); 
1.224     brouard  2220: #endif
1.239     brouard  2221:  int i,ibig,j,jk,k; 
1.126     brouard  2222:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2223:   double directest;
1.126     brouard  2224:   double fp,fptt;
                   2225:   double *xits;
                   2226:   int niterf, itmp;
1.224     brouard  2227: #ifdef LINMINORIGINAL
                   2228: #else
                   2229: 
                   2230:   flatdir=ivector(1,n); 
                   2231:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2232: #endif
1.126     brouard  2233: 
                   2234:   pt=vector(1,n); 
                   2235:   ptt=vector(1,n); 
                   2236:   xit=vector(1,n); 
                   2237:   xits=vector(1,n); 
                   2238:   *fret=(*func)(p); 
                   2239:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2240:   rcurr_time = time(NULL);  
1.126     brouard  2241:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2242:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2243:     ibig=0; 
                   2244:     del=0.0; 
1.157     brouard  2245:     rlast_time=rcurr_time;
                   2246:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2247:     rcurr_time = time(NULL);  
                   2248:     curr_time = *localtime(&rcurr_time);
                   2249:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2250:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2251: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2252:     for (i=1;i<=n;i++) {
1.126     brouard  2253:       fprintf(ficrespow," %.12lf", p[i]);
                   2254:     }
1.239     brouard  2255:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2256:     printf("\n#model=  1      +     age ");
                   2257:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2258:     if(nagesqr==1){
1.241     brouard  2259:        printf("  + age*age  ");
                   2260:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2261:     }
                   2262:     for(j=1;j <=ncovmodel-2;j++){
                   2263:       if(Typevar[j]==0) {
                   2264:        printf("  +      V%d  ",Tvar[j]);
                   2265:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2266:       }else if(Typevar[j]==1) {
                   2267:        printf("  +    V%d*age ",Tvar[j]);
                   2268:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2269:       }else if(Typevar[j]==2) {
                   2270:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2271:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2272:       }
                   2273:     }
1.126     brouard  2274:     printf("\n");
1.239     brouard  2275: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2276: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2277:     fprintf(ficlog,"\n");
1.239     brouard  2278:     for(i=1,jk=1; i <=nlstate; i++){
                   2279:       for(k=1; k <=(nlstate+ndeath); k++){
                   2280:        if (k != i) {
                   2281:          printf("%d%d ",i,k);
                   2282:          fprintf(ficlog,"%d%d ",i,k);
                   2283:          for(j=1; j <=ncovmodel; j++){
                   2284:            printf("%12.7f ",p[jk]);
                   2285:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2286:            jk++; 
                   2287:          }
                   2288:          printf("\n");
                   2289:          fprintf(ficlog,"\n");
                   2290:        }
                   2291:       }
                   2292:     }
1.241     brouard  2293:     if(*iter <=3 && *iter >1){
1.157     brouard  2294:       tml = *localtime(&rcurr_time);
                   2295:       strcpy(strcurr,asctime(&tml));
                   2296:       rforecast_time=rcurr_time; 
1.126     brouard  2297:       itmp = strlen(strcurr);
                   2298:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2299:        strcurr[itmp-1]='\0';
1.162     brouard  2300:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2301:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2302:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2303:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2304:        forecast_time = *localtime(&rforecast_time);
                   2305:        strcpy(strfor,asctime(&forecast_time));
                   2306:        itmp = strlen(strfor);
                   2307:        if(strfor[itmp-1]=='\n')
                   2308:          strfor[itmp-1]='\0';
                   2309:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2310:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2311:       }
                   2312:     }
1.187     brouard  2313:     for (i=1;i<=n;i++) { /* For each direction i */
                   2314:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2315:       fptt=(*fret); 
                   2316: #ifdef DEBUG
1.203     brouard  2317:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2318:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2319: #endif
1.203     brouard  2320:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2321:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2322: #ifdef LINMINORIGINAL
1.188     brouard  2323:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2324: #else
                   2325:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2326:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2327: #endif
                   2328:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2329:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2330:                                /* because that direction will be replaced unless the gain del is small */
                   2331:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2332:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2333:                                /* with the new direction. */
                   2334:                                del=fabs(fptt-(*fret)); 
                   2335:                                ibig=i; 
1.126     brouard  2336:       } 
                   2337: #ifdef DEBUG
                   2338:       printf("%d %.12e",i,(*fret));
                   2339:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2340:       for (j=1;j<=n;j++) {
1.224     brouard  2341:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2342:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2343:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2344:       }
                   2345:       for(j=1;j<=n;j++) {
1.225     brouard  2346:                                printf(" p(%d)=%.12e",j,p[j]);
                   2347:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2348:       }
                   2349:       printf("\n");
                   2350:       fprintf(ficlog,"\n");
                   2351: #endif
1.187     brouard  2352:     } /* end loop on each direction i */
                   2353:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2354:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2355:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2356:       for(j=1;j<=n;j++) {
1.225     brouard  2357:                                if(flatdir[j] >0){
                   2358:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2359:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2360:                                }
                   2361:                                /* printf("\n"); */
                   2362:                                /* fprintf(ficlog,"\n"); */
                   2363:                        }
1.243     brouard  2364:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2365:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2366:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2367:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2368:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2369:       /* decreased of more than 3.84  */
                   2370:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2371:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2372:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2373:                        
1.188     brouard  2374:       /* Starting the program with initial values given by a former maximization will simply change */
                   2375:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2376:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2377:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2378: #ifdef DEBUG
                   2379:       int k[2],l;
                   2380:       k[0]=1;
                   2381:       k[1]=-1;
                   2382:       printf("Max: %.12e",(*func)(p));
                   2383:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2384:       for (j=1;j<=n;j++) {
                   2385:        printf(" %.12e",p[j]);
                   2386:        fprintf(ficlog," %.12e",p[j]);
                   2387:       }
                   2388:       printf("\n");
                   2389:       fprintf(ficlog,"\n");
                   2390:       for(l=0;l<=1;l++) {
                   2391:        for (j=1;j<=n;j++) {
                   2392:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2393:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2394:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2395:        }
                   2396:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2397:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2398:       }
                   2399: #endif
                   2400: 
1.224     brouard  2401: #ifdef LINMINORIGINAL
                   2402: #else
                   2403:       free_ivector(flatdir,1,n); 
                   2404: #endif
1.126     brouard  2405:       free_vector(xit,1,n); 
                   2406:       free_vector(xits,1,n); 
                   2407:       free_vector(ptt,1,n); 
                   2408:       free_vector(pt,1,n); 
                   2409:       return; 
1.192     brouard  2410:     } /* enough precision */ 
1.240     brouard  2411:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2412:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2413:       ptt[j]=2.0*p[j]-pt[j]; 
                   2414:       xit[j]=p[j]-pt[j]; 
                   2415:       pt[j]=p[j]; 
                   2416:     } 
1.181     brouard  2417:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2418: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2419:                if (*iter <=4) {
1.225     brouard  2420: #else
                   2421: #endif
1.224     brouard  2422: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2423: #else
1.161     brouard  2424:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2425: #endif
1.162     brouard  2426:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2427:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2428:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2429:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2430:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2431:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2432:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2433:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2434:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2435:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2436:       /* mu² and del² are equal when f3=f1 */
                   2437:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2438:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2439:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2440:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2441: #ifdef NRCORIGINAL
                   2442:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2443: #else
                   2444:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2445:       t= t- del*SQR(fp-fptt);
1.183     brouard  2446: #endif
1.202     brouard  2447:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2448: #ifdef DEBUG
1.181     brouard  2449:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2450:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2451:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2452:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2453:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2454:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2455:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2456:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2457: #endif
1.183     brouard  2458: #ifdef POWELLORIGINAL
                   2459:       if (t < 0.0) { /* Then we use it for new direction */
                   2460: #else
1.182     brouard  2461:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2462:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2463:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2464:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2465:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2466:       } 
1.181     brouard  2467:       if (directest < 0.0) { /* Then we use it for new direction */
                   2468: #endif
1.191     brouard  2469: #ifdef DEBUGLINMIN
1.234     brouard  2470:        printf("Before linmin in direction P%d-P0\n",n);
                   2471:        for (j=1;j<=n;j++) {
                   2472:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2473:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2474:          if(j % ncovmodel == 0){
                   2475:            printf("\n");
                   2476:            fprintf(ficlog,"\n");
                   2477:          }
                   2478:        }
1.224     brouard  2479: #endif
                   2480: #ifdef LINMINORIGINAL
1.234     brouard  2481:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2482: #else
1.234     brouard  2483:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2484:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2485: #endif
1.234     brouard  2486:        
1.191     brouard  2487: #ifdef DEBUGLINMIN
1.234     brouard  2488:        for (j=1;j<=n;j++) { 
                   2489:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2490:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2491:          if(j % ncovmodel == 0){
                   2492:            printf("\n");
                   2493:            fprintf(ficlog,"\n");
                   2494:          }
                   2495:        }
1.224     brouard  2496: #endif
1.234     brouard  2497:        for (j=1;j<=n;j++) { 
                   2498:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2499:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2500:        }
1.224     brouard  2501: #ifdef LINMINORIGINAL
                   2502: #else
1.234     brouard  2503:        for (j=1, flatd=0;j<=n;j++) {
                   2504:          if(flatdir[j]>0)
                   2505:            flatd++;
                   2506:        }
                   2507:        if(flatd >0){
1.255     brouard  2508:          printf("%d flat directions: ",flatd);
                   2509:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2510:          for (j=1;j<=n;j++) { 
                   2511:            if(flatdir[j]>0){
                   2512:              printf("%d ",j);
                   2513:              fprintf(ficlog,"%d ",j);
                   2514:            }
                   2515:          }
                   2516:          printf("\n");
                   2517:          fprintf(ficlog,"\n");
                   2518:        }
1.191     brouard  2519: #endif
1.234     brouard  2520:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2521:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2522:        
1.126     brouard  2523: #ifdef DEBUG
1.234     brouard  2524:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2525:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2526:        for(j=1;j<=n;j++){
                   2527:          printf(" %lf",xit[j]);
                   2528:          fprintf(ficlog," %lf",xit[j]);
                   2529:        }
                   2530:        printf("\n");
                   2531:        fprintf(ficlog,"\n");
1.126     brouard  2532: #endif
1.192     brouard  2533:       } /* end of t or directest negative */
1.224     brouard  2534: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2535: #else
1.234     brouard  2536:       } /* end if (fptt < fp)  */
1.192     brouard  2537: #endif
1.225     brouard  2538: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2539:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2540: #else
1.224     brouard  2541: #endif
1.234     brouard  2542:                } /* loop iteration */ 
1.126     brouard  2543: } 
1.234     brouard  2544:   
1.126     brouard  2545: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2546:   
1.235     brouard  2547:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2548:   {
1.279     brouard  2549:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2550:      *   (and selected quantitative values in nres)
                   2551:      *  by left multiplying the unit
                   2552:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2553:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2554:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2555:      * or prevalence in state 1, prevalence in state 2, 0
                   2556:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2557:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2558:      * Output is prlim.
                   2559:      * Initial matrix pimij 
                   2560:      */
1.206     brouard  2561:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2562:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2563:   /*  0,                   0                  , 1} */
                   2564:   /*
                   2565:    * and after some iteration: */
                   2566:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2567:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2568:   /*  0,                   0                  , 1} */
                   2569:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2570:   /* {0.51571254859325999, 0.4842874514067399, */
                   2571:   /*  0.51326036147820708, 0.48673963852179264} */
                   2572:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2573:     
1.126     brouard  2574:   int i, ii,j,k;
1.209     brouard  2575:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2576:   /* double **matprod2(); */ /* test */
1.218     brouard  2577:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2578:   double **newm;
1.209     brouard  2579:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2580:   int ncvloop=0;
1.288   ! brouard  2581:   int first=0;
1.169     brouard  2582:   
1.209     brouard  2583:   min=vector(1,nlstate);
                   2584:   max=vector(1,nlstate);
                   2585:   meandiff=vector(1,nlstate);
                   2586: 
1.218     brouard  2587:        /* Starting with matrix unity */
1.126     brouard  2588:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2589:     for (j=1;j<=nlstate+ndeath;j++){
                   2590:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2591:     }
1.169     brouard  2592:   
                   2593:   cov[1]=1.;
                   2594:   
                   2595:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2596:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2597:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2598:     ncvloop++;
1.126     brouard  2599:     newm=savm;
                   2600:     /* Covariates have to be included here again */
1.138     brouard  2601:     cov[2]=agefin;
1.187     brouard  2602:     if(nagesqr==1)
                   2603:       cov[3]= agefin*agefin;;
1.234     brouard  2604:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2605:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2606:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2607:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2608:     }
                   2609:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2610:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2611:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2612:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2613:     }
1.237     brouard  2614:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2615:       if(Dummy[Tvar[Tage[k]]]){
                   2616:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2617:       } else{
1.235     brouard  2618:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2619:       }
1.235     brouard  2620:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2621:     }
1.237     brouard  2622:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2623:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2624:       if(Dummy[Tvard[k][1]==0]){
                   2625:        if(Dummy[Tvard[k][2]==0]){
                   2626:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2627:        }else{
                   2628:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2629:        }
                   2630:       }else{
                   2631:        if(Dummy[Tvard[k][2]==0]){
                   2632:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2633:        }else{
                   2634:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2635:        }
                   2636:       }
1.234     brouard  2637:     }
1.138     brouard  2638:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2639:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2640:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2641:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2642:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2643:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2644:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2645:     
1.126     brouard  2646:     savm=oldm;
                   2647:     oldm=newm;
1.209     brouard  2648: 
                   2649:     for(j=1; j<=nlstate; j++){
                   2650:       max[j]=0.;
                   2651:       min[j]=1.;
                   2652:     }
                   2653:     for(i=1;i<=nlstate;i++){
                   2654:       sumnew=0;
                   2655:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2656:       for(j=1; j<=nlstate; j++){ 
                   2657:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2658:        max[j]=FMAX(max[j],prlim[i][j]);
                   2659:        min[j]=FMIN(min[j],prlim[i][j]);
                   2660:       }
                   2661:     }
                   2662: 
1.126     brouard  2663:     maxmax=0.;
1.209     brouard  2664:     for(j=1; j<=nlstate; j++){
                   2665:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2666:       maxmax=FMAX(maxmax,meandiff[j]);
                   2667:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2668:     } /* j loop */
1.203     brouard  2669:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2670:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2671:     if(maxmax < ftolpl){
1.209     brouard  2672:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2673:       free_vector(min,1,nlstate);
                   2674:       free_vector(max,1,nlstate);
                   2675:       free_vector(meandiff,1,nlstate);
1.126     brouard  2676:       return prlim;
                   2677:     }
1.288   ! brouard  2678:   } /* agefin loop */
1.208     brouard  2679:     /* After some age loop it doesn't converge */
1.288   ! brouard  2680:   if(!first){
        !          2681:     first=1;
        !          2682:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
        !          2683:   }
        !          2684:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
        !          2685: 
1.209     brouard  2686:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2687:   free_vector(min,1,nlstate);
                   2688:   free_vector(max,1,nlstate);
                   2689:   free_vector(meandiff,1,nlstate);
1.208     brouard  2690:   
1.169     brouard  2691:   return prlim; /* should not reach here */
1.126     brouard  2692: }
                   2693: 
1.217     brouard  2694: 
                   2695:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2696: 
1.218     brouard  2697:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2698:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2699:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2700: {
1.264     brouard  2701:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2702:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2703:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2704:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2705:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2706:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2707:   /* Initial matrix pimij */
                   2708:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2709:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2710:   /*  0,                   0                  , 1} */
                   2711:   /*
                   2712:    * and after some iteration: */
                   2713:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2714:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2715:   /*  0,                   0                  , 1} */
                   2716:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2717:   /* {0.51571254859325999, 0.4842874514067399, */
                   2718:   /*  0.51326036147820708, 0.48673963852179264} */
                   2719:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2720: 
                   2721:   int i, ii,j,k;
1.247     brouard  2722:   int first=0;
1.217     brouard  2723:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2724:   /* double **matprod2(); */ /* test */
                   2725:   double **out, cov[NCOVMAX+1], **bmij();
                   2726:   double **newm;
1.218     brouard  2727:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2728:   double        **oldm, **savm;  /* for use */
                   2729: 
1.217     brouard  2730:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2731:   int ncvloop=0;
                   2732:   
                   2733:   min=vector(1,nlstate);
                   2734:   max=vector(1,nlstate);
                   2735:   meandiff=vector(1,nlstate);
                   2736: 
1.266     brouard  2737:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2738:   oldm=oldms; savm=savms;
                   2739:   
                   2740:   /* Starting with matrix unity */
                   2741:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2742:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2743:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2744:     }
                   2745:   
                   2746:   cov[1]=1.;
                   2747:   
                   2748:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2749:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2750:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288   ! brouard  2751:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
        !          2752:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2753:     ncvloop++;
1.218     brouard  2754:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2755:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2756:     /* Covariates have to be included here again */
                   2757:     cov[2]=agefin;
                   2758:     if(nagesqr==1)
                   2759:       cov[3]= agefin*agefin;;
1.242     brouard  2760:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2761:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2762:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2763:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2764:     }
                   2765:     /* for (k=1; k<=cptcovn;k++) { */
                   2766:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2767:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2768:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2769:     /* } */
                   2770:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2771:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2772:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2773:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2774:     }
                   2775:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2776:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2777:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2778:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2779:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2780:       if(Dummy[Tvar[Tage[k]]]){
                   2781:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2782:       } else{
                   2783:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2784:       }
                   2785:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2786:     }
                   2787:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2788:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2789:       if(Dummy[Tvard[k][1]==0]){
                   2790:        if(Dummy[Tvard[k][2]==0]){
                   2791:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2792:        }else{
                   2793:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2794:        }
                   2795:       }else{
                   2796:        if(Dummy[Tvard[k][2]==0]){
                   2797:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2798:        }else{
                   2799:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2800:        }
                   2801:       }
1.217     brouard  2802:     }
                   2803:     
                   2804:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2805:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2806:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2807:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2808:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2809:                /* ij should be linked to the correct index of cov */
                   2810:                /* age and covariate values ij are in 'cov', but we need to pass
                   2811:                 * ij for the observed prevalence at age and status and covariate
                   2812:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2813:                 */
                   2814:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2815:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2816:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2817:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2818:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2819:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2820:     /*         printf("%d newm= ",i); */
                   2821:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2822:     /*           printf("%f ",newm[i][j]); */
                   2823:     /*         } */
                   2824:     /*         printf("oldm * "); */
                   2825:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2826:     /*           printf("%f ",oldm[i][j]); */
                   2827:     /*         } */
1.268     brouard  2828:     /*         printf(" bmmij "); */
1.266     brouard  2829:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2830:     /*           printf("%f ",pmmij[i][j]); */
                   2831:     /*         } */
                   2832:     /*         printf("\n"); */
                   2833:     /*   } */
                   2834:     /* } */
1.217     brouard  2835:     savm=oldm;
                   2836:     oldm=newm;
1.266     brouard  2837: 
1.217     brouard  2838:     for(j=1; j<=nlstate; j++){
                   2839:       max[j]=0.;
                   2840:       min[j]=1.;
                   2841:     }
                   2842:     for(j=1; j<=nlstate; j++){ 
                   2843:       for(i=1;i<=nlstate;i++){
1.234     brouard  2844:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2845:        bprlim[i][j]= newm[i][j];
                   2846:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2847:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2848:       }
                   2849:     }
1.218     brouard  2850:                
1.217     brouard  2851:     maxmax=0.;
                   2852:     for(i=1; i<=nlstate; i++){
                   2853:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2854:       maxmax=FMAX(maxmax,meandiff[i]);
                   2855:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2856:     } /* i loop */
1.217     brouard  2857:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2858:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2859:     if(maxmax < ftolpl){
1.220     brouard  2860:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2861:       free_vector(min,1,nlstate);
                   2862:       free_vector(max,1,nlstate);
                   2863:       free_vector(meandiff,1,nlstate);
                   2864:       return bprlim;
                   2865:     }
1.288   ! brouard  2866:   } /* agefin loop */
1.217     brouard  2867:     /* After some age loop it doesn't converge */
1.288   ! brouard  2868:   if(!first){
1.247     brouard  2869:     first=1;
                   2870:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2871: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2872:   }
                   2873:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2874: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2875:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2876:   free_vector(min,1,nlstate);
                   2877:   free_vector(max,1,nlstate);
                   2878:   free_vector(meandiff,1,nlstate);
                   2879:   
                   2880:   return bprlim; /* should not reach here */
                   2881: }
                   2882: 
1.126     brouard  2883: /*************** transition probabilities ***************/ 
                   2884: 
                   2885: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2886: {
1.138     brouard  2887:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2888:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2889:      model to the ncovmodel covariates (including constant and age).
                   2890:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2891:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2892:      ncth covariate in the global vector x is given by the formula:
                   2893:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2894:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2895:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2896:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2897:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2898:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2899:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2900:   */
                   2901:   double s1, lnpijopii;
1.126     brouard  2902:   /*double t34;*/
1.164     brouard  2903:   int i,j, nc, ii, jj;
1.126     brouard  2904: 
1.223     brouard  2905:   for(i=1; i<= nlstate; i++){
                   2906:     for(j=1; j<i;j++){
                   2907:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2908:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2909:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2910:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2911:       }
                   2912:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2913:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2914:     }
                   2915:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2916:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2917:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2918:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2919:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2920:       }
                   2921:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2922:     }
                   2923:   }
1.218     brouard  2924:   
1.223     brouard  2925:   for(i=1; i<= nlstate; i++){
                   2926:     s1=0;
                   2927:     for(j=1; j<i; j++){
                   2928:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2929:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2930:     }
                   2931:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2932:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2933:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2934:     }
                   2935:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2936:     ps[i][i]=1./(s1+1.);
                   2937:     /* Computing other pijs */
                   2938:     for(j=1; j<i; j++)
                   2939:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2940:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2941:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2942:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2943:   } /* end i */
1.218     brouard  2944:   
1.223     brouard  2945:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2946:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2947:       ps[ii][jj]=0;
                   2948:       ps[ii][ii]=1;
                   2949:     }
                   2950:   }
1.218     brouard  2951:   
                   2952:   
1.223     brouard  2953:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2954:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2955:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2956:   /*   } */
                   2957:   /*   printf("\n "); */
                   2958:   /* } */
                   2959:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2960:   /*
                   2961:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2962:                goto end;*/
1.266     brouard  2963:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2964: }
                   2965: 
1.218     brouard  2966: /*************** backward transition probabilities ***************/ 
                   2967: 
                   2968:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2969: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2970:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2971: {
1.266     brouard  2972:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2973:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2974:    */
1.218     brouard  2975:   int i, ii, j,k;
1.222     brouard  2976:   
                   2977:   double **out, **pmij();
                   2978:   double sumnew=0.;
1.218     brouard  2979:   double agefin;
1.268     brouard  2980:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2981:   double **dnewm, **dsavm, **doldm;
                   2982:   double **bbmij;
                   2983:   
1.218     brouard  2984:   doldm=ddoldms; /* global pointers */
1.222     brouard  2985:   dnewm=ddnewms;
                   2986:   dsavm=ddsavms;
                   2987:   
                   2988:   agefin=cov[2];
1.268     brouard  2989:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2990:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2991:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2992:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2993: 
                   2994:   /* P_x */
1.266     brouard  2995:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2996:   /* outputs pmmij which is a stochastic matrix in row */
                   2997: 
                   2998:   /* Diag(w_x) */
                   2999:   /* Problem with prevacurrent which can be zero */
                   3000:   sumnew=0.;
1.269     brouard  3001:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3002:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  3003:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  3004:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3005:   }
                   3006:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3007:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3008:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3009:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3010:     }
                   3011:   }else{
                   3012:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3013:       for (j=1;j<=nlstate+ndeath;j++)
                   3014:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3015:     }
                   3016:     /* if(sumnew <0.9){ */
                   3017:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3018:     /* } */
                   3019:   }
                   3020:   k3=0.0;  /* We put the last diagonal to 0 */
                   3021:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3022:       doldm[ii][ii]= k3;
                   3023:   }
                   3024:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3025:   
                   3026:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   3027:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   3028: 
                   3029:   /* Diag(Sum_i w^i_x p^ij_x */
                   3030:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3031:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3032:     sumnew=0.;
1.222     brouard  3033:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3034:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3035:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3036:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3037:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3038:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3039:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3040:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3041:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3042:        /* }else */
1.268     brouard  3043:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3044:     } /*End ii */
                   3045:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3046: 
                   3047:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   3048:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3049:   /* end bmij */
1.266     brouard  3050:   return ps; /*pointer is unchanged */
1.218     brouard  3051: }
1.217     brouard  3052: /*************** transition probabilities ***************/ 
                   3053: 
1.218     brouard  3054: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3055: {
                   3056:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3057:      computes the probability to be observed in state j being in state i by appying the
                   3058:      model to the ncovmodel covariates (including constant and age).
                   3059:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3060:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3061:      ncth covariate in the global vector x is given by the formula:
                   3062:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3063:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3064:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3065:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3066:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3067:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3068:   */
                   3069:   double s1, lnpijopii;
                   3070:   /*double t34;*/
                   3071:   int i,j, nc, ii, jj;
                   3072: 
1.234     brouard  3073:   for(i=1; i<= nlstate; i++){
                   3074:     for(j=1; j<i;j++){
                   3075:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3076:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3077:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3078:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3079:       }
                   3080:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3081:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3082:     }
                   3083:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3084:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3085:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3086:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3087:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3088:       }
                   3089:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3090:     }
                   3091:   }
                   3092:   
                   3093:   for(i=1; i<= nlstate; i++){
                   3094:     s1=0;
                   3095:     for(j=1; j<i; j++){
                   3096:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3097:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3098:     }
                   3099:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3100:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3101:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3102:     }
                   3103:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3104:     ps[i][i]=1./(s1+1.);
                   3105:     /* Computing other pijs */
                   3106:     for(j=1; j<i; j++)
                   3107:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3108:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3109:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3110:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3111:   } /* end i */
                   3112:   
                   3113:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3114:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3115:       ps[ii][jj]=0;
                   3116:       ps[ii][ii]=1;
                   3117:     }
                   3118:   }
                   3119:   /* Added for backcast */ /* Transposed matrix too */
                   3120:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3121:     s1=0.;
                   3122:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3123:       s1+=ps[ii][jj];
                   3124:     }
                   3125:     for(ii=1; ii<= nlstate; ii++){
                   3126:       ps[ii][jj]=ps[ii][jj]/s1;
                   3127:     }
                   3128:   }
                   3129:   /* Transposition */
                   3130:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3131:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3132:       s1=ps[ii][jj];
                   3133:       ps[ii][jj]=ps[jj][ii];
                   3134:       ps[jj][ii]=s1;
                   3135:     }
                   3136:   }
                   3137:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3138:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3139:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3140:   /*   } */
                   3141:   /*   printf("\n "); */
                   3142:   /* } */
                   3143:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3144:   /*
                   3145:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3146:     goto end;*/
                   3147:   return ps;
1.217     brouard  3148: }
                   3149: 
                   3150: 
1.126     brouard  3151: /**************** Product of 2 matrices ******************/
                   3152: 
1.145     brouard  3153: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3154: {
                   3155:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3156:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3157:   /* in, b, out are matrice of pointers which should have been initialized 
                   3158:      before: only the contents of out is modified. The function returns
                   3159:      a pointer to pointers identical to out */
1.145     brouard  3160:   int i, j, k;
1.126     brouard  3161:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3162:     for(k=ncolol; k<=ncoloh; k++){
                   3163:       out[i][k]=0.;
                   3164:       for(j=ncl; j<=nch; j++)
                   3165:        out[i][k] +=in[i][j]*b[j][k];
                   3166:     }
1.126     brouard  3167:   return out;
                   3168: }
                   3169: 
                   3170: 
                   3171: /************* Higher Matrix Product ***************/
                   3172: 
1.235     brouard  3173: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3174: {
1.218     brouard  3175:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3176:      'nhstepm*hstepm*stepm' months (i.e. until
                   3177:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3178:      nhstepm*hstepm matrices. 
                   3179:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3180:      (typically every 2 years instead of every month which is too big 
                   3181:      for the memory).
                   3182:      Model is determined by parameters x and covariates have to be 
                   3183:      included manually here. 
                   3184: 
                   3185:      */
                   3186: 
                   3187:   int i, j, d, h, k;
1.131     brouard  3188:   double **out, cov[NCOVMAX+1];
1.126     brouard  3189:   double **newm;
1.187     brouard  3190:   double agexact;
1.214     brouard  3191:   double agebegin, ageend;
1.126     brouard  3192: 
                   3193:   /* Hstepm could be zero and should return the unit matrix */
                   3194:   for (i=1;i<=nlstate+ndeath;i++)
                   3195:     for (j=1;j<=nlstate+ndeath;j++){
                   3196:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3197:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3198:     }
                   3199:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3200:   for(h=1; h <=nhstepm; h++){
                   3201:     for(d=1; d <=hstepm; d++){
                   3202:       newm=savm;
                   3203:       /* Covariates have to be included here again */
                   3204:       cov[1]=1.;
1.214     brouard  3205:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3206:       cov[2]=agexact;
                   3207:       if(nagesqr==1)
1.227     brouard  3208:        cov[3]= agexact*agexact;
1.235     brouard  3209:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3210:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3211:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3212:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3213:       }
                   3214:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3215:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3216:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3217:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3218:       }
                   3219:       for (k=1; k<=cptcovage;k++){
                   3220:        if(Dummy[Tvar[Tage[k]]]){
                   3221:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3222:        } else{
                   3223:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3224:        }
                   3225:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3226:       }
                   3227:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3228:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3229:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3230:       }
                   3231:       /* for (k=1; k<=cptcovn;k++)  */
                   3232:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3233:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3234:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3235:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3236:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3237:       
                   3238:       
1.126     brouard  3239:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3240:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3241:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3242:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3243:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3244:       /* if((int)age == 70){ */
                   3245:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3246:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3247:       /*         printf("%d pmmij ",i); */
                   3248:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3249:       /*           printf("%f ",pmmij[i][j]); */
                   3250:       /*         } */
                   3251:       /*         printf(" oldm "); */
                   3252:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3253:       /*           printf("%f ",oldm[i][j]); */
                   3254:       /*         } */
                   3255:       /*         printf("\n"); */
                   3256:       /*       } */
                   3257:       /* } */
1.126     brouard  3258:       savm=oldm;
                   3259:       oldm=newm;
                   3260:     }
                   3261:     for(i=1; i<=nlstate+ndeath; i++)
                   3262:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3263:        po[i][j][h]=newm[i][j];
                   3264:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3265:       }
1.128     brouard  3266:     /*printf("h=%d ",h);*/
1.126     brouard  3267:   } /* end h */
1.267     brouard  3268:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3269:   return po;
                   3270: }
                   3271: 
1.217     brouard  3272: /************* Higher Back Matrix Product ***************/
1.218     brouard  3273: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3274: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3275: {
1.266     brouard  3276:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3277:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3278:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3279:      nhstepm*hstepm matrices.
                   3280:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3281:      (typically every 2 years instead of every month which is too big
1.217     brouard  3282:      for the memory).
1.218     brouard  3283:      Model is determined by parameters x and covariates have to be
1.266     brouard  3284:      included manually here. Then we use a call to bmij(x and cov)
                   3285:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3286:   */
1.217     brouard  3287: 
                   3288:   int i, j, d, h, k;
1.266     brouard  3289:   double **out, cov[NCOVMAX+1], **bmij();
                   3290:   double **newm, ***newmm;
1.217     brouard  3291:   double agexact;
                   3292:   double agebegin, ageend;
1.222     brouard  3293:   double **oldm, **savm;
1.217     brouard  3294: 
1.266     brouard  3295:   newmm=po; /* To be saved */
                   3296:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3297:   /* Hstepm could be zero and should return the unit matrix */
                   3298:   for (i=1;i<=nlstate+ndeath;i++)
                   3299:     for (j=1;j<=nlstate+ndeath;j++){
                   3300:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3301:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3302:     }
                   3303:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3304:   for(h=1; h <=nhstepm; h++){
                   3305:     for(d=1; d <=hstepm; d++){
                   3306:       newm=savm;
                   3307:       /* Covariates have to be included here again */
                   3308:       cov[1]=1.;
1.271     brouard  3309:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3310:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3311:       cov[2]=agexact;
                   3312:       if(nagesqr==1)
1.222     brouard  3313:        cov[3]= agexact*agexact;
1.266     brouard  3314:       for (k=1; k<=cptcovn;k++){
                   3315:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3316:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3317:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3318:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3319:       }
1.267     brouard  3320:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3321:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3322:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3323:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3324:       }
                   3325:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3326:        if(Dummy[Tvar[Tage[k]]]){
                   3327:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3328:        } else{
                   3329:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3330:        }
                   3331:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3332:       }
                   3333:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3334:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3335:       }                        
1.217     brouard  3336:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3337:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3338: 
1.218     brouard  3339:       /* Careful transposed matrix */
1.266     brouard  3340:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3341:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3342:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3343:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3344:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3345:       /* if((int)age == 70){ */
                   3346:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3347:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3348:       /*         printf("%d pmmij ",i); */
                   3349:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3350:       /*           printf("%f ",pmmij[i][j]); */
                   3351:       /*         } */
                   3352:       /*         printf(" oldm "); */
                   3353:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3354:       /*           printf("%f ",oldm[i][j]); */
                   3355:       /*         } */
                   3356:       /*         printf("\n"); */
                   3357:       /*       } */
                   3358:       /* } */
                   3359:       savm=oldm;
                   3360:       oldm=newm;
                   3361:     }
                   3362:     for(i=1; i<=nlstate+ndeath; i++)
                   3363:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3364:        po[i][j][h]=newm[i][j];
1.268     brouard  3365:        /* if(h==nhstepm) */
                   3366:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3367:       }
1.268     brouard  3368:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3369:   } /* end h */
1.268     brouard  3370:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3371:   return po;
                   3372: }
                   3373: 
                   3374: 
1.162     brouard  3375: #ifdef NLOPT
                   3376:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3377:   double fret;
                   3378:   double *xt;
                   3379:   int j;
                   3380:   myfunc_data *d2 = (myfunc_data *) pd;
                   3381: /* xt = (p1-1); */
                   3382:   xt=vector(1,n); 
                   3383:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3384: 
                   3385:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3386:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3387:   printf("Function = %.12lf ",fret);
                   3388:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3389:   printf("\n");
                   3390:  free_vector(xt,1,n);
                   3391:   return fret;
                   3392: }
                   3393: #endif
1.126     brouard  3394: 
                   3395: /*************** log-likelihood *************/
                   3396: double func( double *x)
                   3397: {
1.226     brouard  3398:   int i, ii, j, k, mi, d, kk;
                   3399:   int ioffset=0;
                   3400:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3401:   double **out;
                   3402:   double lli; /* Individual log likelihood */
                   3403:   int s1, s2;
1.228     brouard  3404:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3405:   double bbh, survp;
                   3406:   long ipmx;
                   3407:   double agexact;
                   3408:   /*extern weight */
                   3409:   /* We are differentiating ll according to initial status */
                   3410:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3411:   /*for(i=1;i<imx;i++) 
                   3412:     printf(" %d\n",s[4][i]);
                   3413:   */
1.162     brouard  3414: 
1.226     brouard  3415:   ++countcallfunc;
1.162     brouard  3416: 
1.226     brouard  3417:   cov[1]=1.;
1.126     brouard  3418: 
1.226     brouard  3419:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3420:   ioffset=0;
1.226     brouard  3421:   if(mle==1){
                   3422:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3423:       /* Computes the values of the ncovmodel covariates of the model
                   3424:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3425:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3426:         to be observed in j being in i according to the model.
                   3427:       */
1.243     brouard  3428:       ioffset=2+nagesqr ;
1.233     brouard  3429:    /* Fixed */
1.234     brouard  3430:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3431:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3432:       }
1.226     brouard  3433:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3434:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3435:         has been calculated etc */
                   3436:       /* For an individual i, wav[i] gives the number of effective waves */
                   3437:       /* We compute the contribution to Likelihood of each effective transition
                   3438:         mw[mi][i] is real wave of the mi th effectve wave */
                   3439:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3440:         s2=s[mw[mi+1][i]][i];
                   3441:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3442:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3443:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3444:       */
                   3445:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3446:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3447:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3448:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3449:        }
                   3450:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3451:          for (j=1;j<=nlstate+ndeath;j++){
                   3452:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3453:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3454:          }
                   3455:        for(d=0; d<dh[mi][i]; d++){
                   3456:          newm=savm;
                   3457:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3458:          cov[2]=agexact;
                   3459:          if(nagesqr==1)
                   3460:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3461:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3462:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3463:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3464:          else
                   3465:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3466:          }
                   3467:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3468:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3469:          savm=oldm;
                   3470:          oldm=newm;
                   3471:        } /* end mult */
                   3472:        
                   3473:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3474:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3475:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3476:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3477:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3478:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3479:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3480:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3481:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3482:                                 * -stepm/2 to stepm/2 .
                   3483:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3484:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3485:                                 */
1.234     brouard  3486:        s1=s[mw[mi][i]][i];
                   3487:        s2=s[mw[mi+1][i]][i];
                   3488:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3489:        /* bias bh is positive if real duration
                   3490:         * is higher than the multiple of stepm and negative otherwise.
                   3491:         */
                   3492:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3493:        if( s2 > nlstate){ 
                   3494:          /* i.e. if s2 is a death state and if the date of death is known 
                   3495:             then the contribution to the likelihood is the probability to 
                   3496:             die between last step unit time and current  step unit time, 
                   3497:             which is also equal to probability to die before dh 
                   3498:             minus probability to die before dh-stepm . 
                   3499:             In version up to 0.92 likelihood was computed
                   3500:             as if date of death was unknown. Death was treated as any other
                   3501:             health state: the date of the interview describes the actual state
                   3502:             and not the date of a change in health state. The former idea was
                   3503:             to consider that at each interview the state was recorded
                   3504:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3505:             introduced the exact date of death then we should have modified
                   3506:             the contribution of an exact death to the likelihood. This new
                   3507:             contribution is smaller and very dependent of the step unit
                   3508:             stepm. It is no more the probability to die between last interview
                   3509:             and month of death but the probability to survive from last
                   3510:             interview up to one month before death multiplied by the
                   3511:             probability to die within a month. Thanks to Chris
                   3512:             Jackson for correcting this bug.  Former versions increased
                   3513:             mortality artificially. The bad side is that we add another loop
                   3514:             which slows down the processing. The difference can be up to 10%
                   3515:             lower mortality.
                   3516:          */
                   3517:          /* If, at the beginning of the maximization mostly, the
                   3518:             cumulative probability or probability to be dead is
                   3519:             constant (ie = 1) over time d, the difference is equal to
                   3520:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3521:             s1 at precedent wave, to be dead a month before current
                   3522:             wave is equal to probability, being at state s1 at
                   3523:             precedent wave, to be dead at mont of the current
                   3524:             wave. Then the observed probability (that this person died)
                   3525:             is null according to current estimated parameter. In fact,
                   3526:             it should be very low but not zero otherwise the log go to
                   3527:             infinity.
                   3528:          */
1.183     brouard  3529: /* #ifdef INFINITYORIGINAL */
                   3530: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3531: /* #else */
                   3532: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3533: /*         lli=log(mytinydouble); */
                   3534: /*       else */
                   3535: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3536: /* #endif */
1.226     brouard  3537:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3538:          
1.226     brouard  3539:        } else if  ( s2==-1 ) { /* alive */
                   3540:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3541:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3542:          /*survp += out[s1][j]; */
                   3543:          lli= log(survp);
                   3544:        }
                   3545:        else if  (s2==-4) { 
                   3546:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3547:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3548:          lli= log(survp); 
                   3549:        } 
                   3550:        else if  (s2==-5) { 
                   3551:          for (j=1,survp=0. ; j<=2; j++)  
                   3552:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3553:          lli= log(survp); 
                   3554:        } 
                   3555:        else{
                   3556:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3557:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3558:        } 
                   3559:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3560:        /*if(lli ==000.0)*/
                   3561:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3562:        ipmx +=1;
                   3563:        sw += weight[i];
                   3564:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3565:        /* if (lli < log(mytinydouble)){ */
                   3566:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3567:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3568:        /* } */
                   3569:       } /* end of wave */
                   3570:     } /* end of individual */
                   3571:   }  else if(mle==2){
                   3572:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3573:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3574:       for(mi=1; mi<= wav[i]-1; mi++){
                   3575:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3576:          for (j=1;j<=nlstate+ndeath;j++){
                   3577:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3578:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3579:          }
                   3580:        for(d=0; d<=dh[mi][i]; d++){
                   3581:          newm=savm;
                   3582:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3583:          cov[2]=agexact;
                   3584:          if(nagesqr==1)
                   3585:            cov[3]= agexact*agexact;
                   3586:          for (kk=1; kk<=cptcovage;kk++) {
                   3587:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3588:          }
                   3589:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3590:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3591:          savm=oldm;
                   3592:          oldm=newm;
                   3593:        } /* end mult */
                   3594:       
                   3595:        s1=s[mw[mi][i]][i];
                   3596:        s2=s[mw[mi+1][i]][i];
                   3597:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3598:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3599:        ipmx +=1;
                   3600:        sw += weight[i];
                   3601:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3602:       } /* end of wave */
                   3603:     } /* end of individual */
                   3604:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3605:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3606:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3607:       for(mi=1; mi<= wav[i]-1; mi++){
                   3608:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3609:          for (j=1;j<=nlstate+ndeath;j++){
                   3610:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3611:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3612:          }
                   3613:        for(d=0; d<dh[mi][i]; d++){
                   3614:          newm=savm;
                   3615:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3616:          cov[2]=agexact;
                   3617:          if(nagesqr==1)
                   3618:            cov[3]= agexact*agexact;
                   3619:          for (kk=1; kk<=cptcovage;kk++) {
                   3620:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3621:          }
                   3622:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3623:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3624:          savm=oldm;
                   3625:          oldm=newm;
                   3626:        } /* end mult */
                   3627:       
                   3628:        s1=s[mw[mi][i]][i];
                   3629:        s2=s[mw[mi+1][i]][i];
                   3630:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3631:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3632:        ipmx +=1;
                   3633:        sw += weight[i];
                   3634:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3635:       } /* end of wave */
                   3636:     } /* end of individual */
                   3637:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3638:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3639:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3640:       for(mi=1; mi<= wav[i]-1; mi++){
                   3641:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3642:          for (j=1;j<=nlstate+ndeath;j++){
                   3643:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3644:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3645:          }
                   3646:        for(d=0; d<dh[mi][i]; d++){
                   3647:          newm=savm;
                   3648:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3649:          cov[2]=agexact;
                   3650:          if(nagesqr==1)
                   3651:            cov[3]= agexact*agexact;
                   3652:          for (kk=1; kk<=cptcovage;kk++) {
                   3653:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3654:          }
1.126     brouard  3655:        
1.226     brouard  3656:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3657:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3658:          savm=oldm;
                   3659:          oldm=newm;
                   3660:        } /* end mult */
                   3661:       
                   3662:        s1=s[mw[mi][i]][i];
                   3663:        s2=s[mw[mi+1][i]][i];
                   3664:        if( s2 > nlstate){ 
                   3665:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3666:        } else if  ( s2==-1 ) { /* alive */
                   3667:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3668:            survp += out[s1][j];
                   3669:          lli= log(survp);
                   3670:        }else{
                   3671:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3672:        }
                   3673:        ipmx +=1;
                   3674:        sw += weight[i];
                   3675:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3676: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3677:       } /* end of wave */
                   3678:     } /* end of individual */
                   3679:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3680:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3681:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3682:       for(mi=1; mi<= wav[i]-1; mi++){
                   3683:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3684:          for (j=1;j<=nlstate+ndeath;j++){
                   3685:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3686:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3687:          }
                   3688:        for(d=0; d<dh[mi][i]; d++){
                   3689:          newm=savm;
                   3690:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3691:          cov[2]=agexact;
                   3692:          if(nagesqr==1)
                   3693:            cov[3]= agexact*agexact;
                   3694:          for (kk=1; kk<=cptcovage;kk++) {
                   3695:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3696:          }
1.126     brouard  3697:        
1.226     brouard  3698:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3699:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3700:          savm=oldm;
                   3701:          oldm=newm;
                   3702:        } /* end mult */
                   3703:       
                   3704:        s1=s[mw[mi][i]][i];
                   3705:        s2=s[mw[mi+1][i]][i];
                   3706:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3707:        ipmx +=1;
                   3708:        sw += weight[i];
                   3709:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3710:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3711:       } /* end of wave */
                   3712:     } /* end of individual */
                   3713:   } /* End of if */
                   3714:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3715:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3716:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3717:   return -l;
1.126     brouard  3718: }
                   3719: 
                   3720: /*************** log-likelihood *************/
                   3721: double funcone( double *x)
                   3722: {
1.228     brouard  3723:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3724:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3725:   int ioffset=0;
1.131     brouard  3726:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3727:   double **out;
                   3728:   double lli; /* Individual log likelihood */
                   3729:   double llt;
                   3730:   int s1, s2;
1.228     brouard  3731:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3732: 
1.126     brouard  3733:   double bbh, survp;
1.187     brouard  3734:   double agexact;
1.214     brouard  3735:   double agebegin, ageend;
1.126     brouard  3736:   /*extern weight */
                   3737:   /* We are differentiating ll according to initial status */
                   3738:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3739:   /*for(i=1;i<imx;i++) 
                   3740:     printf(" %d\n",s[4][i]);
                   3741:   */
                   3742:   cov[1]=1.;
                   3743: 
                   3744:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3745:   ioffset=0;
                   3746:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3747:     /* ioffset=2+nagesqr+cptcovage; */
                   3748:     ioffset=2+nagesqr;
1.232     brouard  3749:     /* Fixed */
1.224     brouard  3750:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3751:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3752:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3753:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3754: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3755: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3756: /*    cov[2+6]=covar[2][i]; V2  */
                   3757: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3758: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3759: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3760: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3761: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3762: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3763:     }
1.232     brouard  3764:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3765:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3766:     /* } */
1.231     brouard  3767:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3768:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3769:     /* } */
1.225     brouard  3770:     
1.233     brouard  3771: 
                   3772:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3773:     /* Wave varying (but not age varying) */
                   3774:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3775:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3776:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3777:       }
1.232     brouard  3778:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3779:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3780:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3781:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3782:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3783:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3784:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3785:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3786:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3787:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3788:       /* } */
1.126     brouard  3789:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3790:        for (j=1;j<=nlstate+ndeath;j++){
                   3791:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3792:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3793:        }
1.214     brouard  3794:       
                   3795:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3796:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3797:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3798:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3799:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3800:          and mw[mi+1][i]. dh depends on stepm.*/
                   3801:        newm=savm;
1.247     brouard  3802:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3803:        cov[2]=agexact;
                   3804:        if(nagesqr==1)
                   3805:          cov[3]= agexact*agexact;
                   3806:        for (kk=1; kk<=cptcovage;kk++) {
                   3807:          if(!FixedV[Tvar[Tage[kk]]])
                   3808:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3809:          else
                   3810:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3811:        }
                   3812:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3813:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3814:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3815:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3816:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3817:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3818:        savm=oldm;
                   3819:        oldm=newm;
1.126     brouard  3820:       } /* end mult */
                   3821:       
                   3822:       s1=s[mw[mi][i]][i];
                   3823:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3824:       /* if(s2==-1){ */
1.268     brouard  3825:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3826:       /*       /\* exit(1); *\/ */
                   3827:       /* } */
1.126     brouard  3828:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3829:       /* bias is positive if real duration
                   3830:        * is higher than the multiple of stepm and negative otherwise.
                   3831:        */
                   3832:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3833:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3834:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3835:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3836:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3837:        lli= log(survp);
1.126     brouard  3838:       }else if (mle==1){
1.242     brouard  3839:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3840:       } else if(mle==2){
1.242     brouard  3841:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3842:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3843:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3844:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3845:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3846:       } else{  /* mle=0 back to 1 */
1.242     brouard  3847:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3848:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3849:       } /* End of if */
                   3850:       ipmx +=1;
                   3851:       sw += weight[i];
                   3852:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3853:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3854:       if(globpr){
1.246     brouard  3855:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3856:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3857:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3858:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3859:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3860:          llt +=ll[k]*gipmx/gsw;
                   3861:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3862:        }
                   3863:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3864:       }
1.232     brouard  3865:        } /* end of wave */
                   3866: } /* end of individual */
                   3867: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3868: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3869: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3870: if(globpr==0){ /* First time we count the contributions and weights */
                   3871:        gipmx=ipmx;
                   3872:        gsw=sw;
                   3873: }
                   3874: return -l;
1.126     brouard  3875: }
                   3876: 
                   3877: 
                   3878: /*************** function likelione ***********/
                   3879: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3880: {
                   3881:   /* This routine should help understanding what is done with 
                   3882:      the selection of individuals/waves and
                   3883:      to check the exact contribution to the likelihood.
                   3884:      Plotting could be done.
                   3885:    */
                   3886:   int k;
                   3887: 
                   3888:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3889:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3890:     strcat(fileresilk,fileresu);
1.126     brouard  3891:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3892:       printf("Problem with resultfile: %s\n", fileresilk);
                   3893:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3894:     }
1.214     brouard  3895:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3896:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3897:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3898:     for(k=1; k<=nlstate; k++) 
                   3899:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3900:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3901:   }
                   3902: 
                   3903:   *fretone=(*funcone)(p);
                   3904:   if(*globpri !=0){
                   3905:     fclose(ficresilk);
1.205     brouard  3906:     if (mle ==0)
                   3907:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3908:     else if(mle >=1)
                   3909:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3910:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3911:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3912:       
                   3913:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3914:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3915: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3916:     }
1.207     brouard  3917:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3918: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3919:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3920: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3921:     fflush(fichtm);
1.205     brouard  3922:   }
1.126     brouard  3923:   return;
                   3924: }
                   3925: 
                   3926: 
                   3927: /*********** Maximum Likelihood Estimation ***************/
                   3928: 
                   3929: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3930: {
1.165     brouard  3931:   int i,j, iter=0;
1.126     brouard  3932:   double **xi;
                   3933:   double fret;
                   3934:   double fretone; /* Only one call to likelihood */
                   3935:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3936: 
                   3937: #ifdef NLOPT
                   3938:   int creturn;
                   3939:   nlopt_opt opt;
                   3940:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3941:   double *lb;
                   3942:   double minf; /* the minimum objective value, upon return */
                   3943:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3944:   myfunc_data dinst, *d = &dinst;
                   3945: #endif
                   3946: 
                   3947: 
1.126     brouard  3948:   xi=matrix(1,npar,1,npar);
                   3949:   for (i=1;i<=npar;i++)
                   3950:     for (j=1;j<=npar;j++)
                   3951:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3952:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3953:   strcpy(filerespow,"POW_"); 
1.126     brouard  3954:   strcat(filerespow,fileres);
                   3955:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3956:     printf("Problem with resultfile: %s\n", filerespow);
                   3957:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3958:   }
                   3959:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3960:   for (i=1;i<=nlstate;i++)
                   3961:     for(j=1;j<=nlstate+ndeath;j++)
                   3962:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3963:   fprintf(ficrespow,"\n");
1.162     brouard  3964: #ifdef POWELL
1.126     brouard  3965:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3966: #endif
1.126     brouard  3967: 
1.162     brouard  3968: #ifdef NLOPT
                   3969: #ifdef NEWUOA
                   3970:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3971: #else
                   3972:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3973: #endif
                   3974:   lb=vector(0,npar-1);
                   3975:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3976:   nlopt_set_lower_bounds(opt, lb);
                   3977:   nlopt_set_initial_step1(opt, 0.1);
                   3978:   
                   3979:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3980:   d->function = func;
                   3981:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3982:   nlopt_set_min_objective(opt, myfunc, d);
                   3983:   nlopt_set_xtol_rel(opt, ftol);
                   3984:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3985:     printf("nlopt failed! %d\n",creturn); 
                   3986:   }
                   3987:   else {
                   3988:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3989:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3990:     iter=1; /* not equal */
                   3991:   }
                   3992:   nlopt_destroy(opt);
                   3993: #endif
1.126     brouard  3994:   free_matrix(xi,1,npar,1,npar);
                   3995:   fclose(ficrespow);
1.203     brouard  3996:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   3997:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  3998:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  3999: 
                   4000: }
                   4001: 
                   4002: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4003: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4004: {
                   4005:   double  **a,**y,*x,pd;
1.203     brouard  4006:   /* double **hess; */
1.164     brouard  4007:   int i, j;
1.126     brouard  4008:   int *indx;
                   4009: 
                   4010:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4011:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4012:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4013:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4014:   double gompertz(double p[]);
1.203     brouard  4015:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4016: 
                   4017:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4018:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4019:   for (i=1;i<=npar;i++){
1.203     brouard  4020:     printf("%d-",i);fflush(stdout);
                   4021:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4022:    
                   4023:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4024:     
                   4025:     /*  printf(" %f ",p[i]);
                   4026:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4027:   }
                   4028:   
                   4029:   for (i=1;i<=npar;i++) {
                   4030:     for (j=1;j<=npar;j++)  {
                   4031:       if (j>i) { 
1.203     brouard  4032:        printf(".%d-%d",i,j);fflush(stdout);
                   4033:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4034:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4035:        
                   4036:        hess[j][i]=hess[i][j];    
                   4037:        /*printf(" %lf ",hess[i][j]);*/
                   4038:       }
                   4039:     }
                   4040:   }
                   4041:   printf("\n");
                   4042:   fprintf(ficlog,"\n");
                   4043: 
                   4044:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4045:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4046:   
                   4047:   a=matrix(1,npar,1,npar);
                   4048:   y=matrix(1,npar,1,npar);
                   4049:   x=vector(1,npar);
                   4050:   indx=ivector(1,npar);
                   4051:   for (i=1;i<=npar;i++)
                   4052:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4053:   ludcmp(a,npar,indx,&pd);
                   4054: 
                   4055:   for (j=1;j<=npar;j++) {
                   4056:     for (i=1;i<=npar;i++) x[i]=0;
                   4057:     x[j]=1;
                   4058:     lubksb(a,npar,indx,x);
                   4059:     for (i=1;i<=npar;i++){ 
                   4060:       matcov[i][j]=x[i];
                   4061:     }
                   4062:   }
                   4063: 
                   4064:   printf("\n#Hessian matrix#\n");
                   4065:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4066:   for (i=1;i<=npar;i++) { 
                   4067:     for (j=1;j<=npar;j++) { 
1.203     brouard  4068:       printf("%.6e ",hess[i][j]);
                   4069:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4070:     }
                   4071:     printf("\n");
                   4072:     fprintf(ficlog,"\n");
                   4073:   }
                   4074: 
1.203     brouard  4075:   /* printf("\n#Covariance matrix#\n"); */
                   4076:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4077:   /* for (i=1;i<=npar;i++) {  */
                   4078:   /*   for (j=1;j<=npar;j++) {  */
                   4079:   /*     printf("%.6e ",matcov[i][j]); */
                   4080:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4081:   /*   } */
                   4082:   /*   printf("\n"); */
                   4083:   /*   fprintf(ficlog,"\n"); */
                   4084:   /* } */
                   4085: 
1.126     brouard  4086:   /* Recompute Inverse */
1.203     brouard  4087:   /* for (i=1;i<=npar;i++) */
                   4088:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4089:   /* ludcmp(a,npar,indx,&pd); */
                   4090: 
                   4091:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4092: 
                   4093:   /* for (j=1;j<=npar;j++) { */
                   4094:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4095:   /*   x[j]=1; */
                   4096:   /*   lubksb(a,npar,indx,x); */
                   4097:   /*   for (i=1;i<=npar;i++){  */
                   4098:   /*     y[i][j]=x[i]; */
                   4099:   /*     printf("%.3e ",y[i][j]); */
                   4100:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4101:   /*   } */
                   4102:   /*   printf("\n"); */
                   4103:   /*   fprintf(ficlog,"\n"); */
                   4104:   /* } */
                   4105: 
                   4106:   /* Verifying the inverse matrix */
                   4107: #ifdef DEBUGHESS
                   4108:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4109: 
1.203     brouard  4110:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4111:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4112: 
                   4113:   for (j=1;j<=npar;j++) {
                   4114:     for (i=1;i<=npar;i++){ 
1.203     brouard  4115:       printf("%.2f ",y[i][j]);
                   4116:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4117:     }
                   4118:     printf("\n");
                   4119:     fprintf(ficlog,"\n");
                   4120:   }
1.203     brouard  4121: #endif
1.126     brouard  4122: 
                   4123:   free_matrix(a,1,npar,1,npar);
                   4124:   free_matrix(y,1,npar,1,npar);
                   4125:   free_vector(x,1,npar);
                   4126:   free_ivector(indx,1,npar);
1.203     brouard  4127:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4128: 
                   4129: 
                   4130: }
                   4131: 
                   4132: /*************** hessian matrix ****************/
                   4133: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4134: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4135:   int i;
                   4136:   int l=1, lmax=20;
1.203     brouard  4137:   double k1,k2, res, fx;
1.132     brouard  4138:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4139:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4140:   int k=0,kmax=10;
                   4141:   double l1;
                   4142: 
                   4143:   fx=func(x);
                   4144:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4145:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4146:     l1=pow(10,l);
                   4147:     delts=delt;
                   4148:     for(k=1 ; k <kmax; k=k+1){
                   4149:       delt = delta*(l1*k);
                   4150:       p2[theta]=x[theta] +delt;
1.145     brouard  4151:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4152:       p2[theta]=x[theta]-delt;
                   4153:       k2=func(p2)-fx;
                   4154:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4155:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4156:       
1.203     brouard  4157: #ifdef DEBUGHESSII
1.126     brouard  4158:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4159:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4160: #endif
                   4161:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4162:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4163:        k=kmax;
                   4164:       }
                   4165:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4166:        k=kmax; l=lmax*10;
1.126     brouard  4167:       }
                   4168:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4169:        delts=delt;
                   4170:       }
1.203     brouard  4171:     } /* End loop k */
1.126     brouard  4172:   }
                   4173:   delti[theta]=delts;
                   4174:   return res; 
                   4175:   
                   4176: }
                   4177: 
1.203     brouard  4178: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4179: {
                   4180:   int i;
1.164     brouard  4181:   int l=1, lmax=20;
1.126     brouard  4182:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4183:   double p2[MAXPARM+1];
1.203     brouard  4184:   int k, kmax=1;
                   4185:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4186: 
                   4187:   int firstime=0;
1.203     brouard  4188:   
1.126     brouard  4189:   fx=func(x);
1.203     brouard  4190:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4191:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4192:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4193:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4194:     k1=func(p2)-fx;
                   4195:   
1.203     brouard  4196:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4197:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4198:     k2=func(p2)-fx;
                   4199:   
1.203     brouard  4200:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4201:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4202:     k3=func(p2)-fx;
                   4203:   
1.203     brouard  4204:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4205:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4206:     k4=func(p2)-fx;
1.203     brouard  4207:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4208:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4209:       firstime=1;
1.203     brouard  4210:       kmax=kmax+10;
1.208     brouard  4211:     }
                   4212:     if(kmax >=10 || firstime ==1){
1.246     brouard  4213:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4214:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4215:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4216:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4217:     }
                   4218: #ifdef DEBUGHESSIJ
                   4219:     v1=hess[thetai][thetai];
                   4220:     v2=hess[thetaj][thetaj];
                   4221:     cv12=res;
                   4222:     /* Computing eigen value of Hessian matrix */
                   4223:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4224:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4225:     if ((lc2 <0) || (lc1 <0) ){
                   4226:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4227:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4228:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4229:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4230:     }
1.126     brouard  4231: #endif
                   4232:   }
                   4233:   return res;
                   4234: }
                   4235: 
1.203     brouard  4236:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4237: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4238: /* { */
                   4239: /*   int i; */
                   4240: /*   int l=1, lmax=20; */
                   4241: /*   double k1,k2,k3,k4,res,fx; */
                   4242: /*   double p2[MAXPARM+1]; */
                   4243: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4244: /*   int k=0,kmax=10; */
                   4245: /*   double l1; */
                   4246:   
                   4247: /*   fx=func(x); */
                   4248: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4249: /*     l1=pow(10,l); */
                   4250: /*     delts=delt; */
                   4251: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4252: /*       delt = delti*(l1*k); */
                   4253: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4254: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4255: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4256: /*       k1=func(p2)-fx; */
                   4257:       
                   4258: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4259: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4260: /*       k2=func(p2)-fx; */
                   4261:       
                   4262: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4263: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4264: /*       k3=func(p2)-fx; */
                   4265:       
                   4266: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4267: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4268: /*       k4=func(p2)-fx; */
                   4269: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4270: /* #ifdef DEBUGHESSIJ */
                   4271: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4272: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4273: /* #endif */
                   4274: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4275: /*     k=kmax; */
                   4276: /*       } */
                   4277: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4278: /*     k=kmax; l=lmax*10; */
                   4279: /*       } */
                   4280: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4281: /*     delts=delt; */
                   4282: /*       } */
                   4283: /*     } /\* End loop k *\/ */
                   4284: /*   } */
                   4285: /*   delti[theta]=delts; */
                   4286: /*   return res;  */
                   4287: /* } */
                   4288: 
                   4289: 
1.126     brouard  4290: /************** Inverse of matrix **************/
                   4291: void ludcmp(double **a, int n, int *indx, double *d) 
                   4292: { 
                   4293:   int i,imax,j,k; 
                   4294:   double big,dum,sum,temp; 
                   4295:   double *vv; 
                   4296:  
                   4297:   vv=vector(1,n); 
                   4298:   *d=1.0; 
                   4299:   for (i=1;i<=n;i++) { 
                   4300:     big=0.0; 
                   4301:     for (j=1;j<=n;j++) 
                   4302:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4303:     if (big == 0.0){
                   4304:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4305:       for (j=1;j<=n;j++) {
                   4306:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4307:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4308:       }
                   4309:       fflush(ficlog);
                   4310:       fclose(ficlog);
                   4311:       nrerror("Singular matrix in routine ludcmp"); 
                   4312:     }
1.126     brouard  4313:     vv[i]=1.0/big; 
                   4314:   } 
                   4315:   for (j=1;j<=n;j++) { 
                   4316:     for (i=1;i<j;i++) { 
                   4317:       sum=a[i][j]; 
                   4318:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4319:       a[i][j]=sum; 
                   4320:     } 
                   4321:     big=0.0; 
                   4322:     for (i=j;i<=n;i++) { 
                   4323:       sum=a[i][j]; 
                   4324:       for (k=1;k<j;k++) 
                   4325:        sum -= a[i][k]*a[k][j]; 
                   4326:       a[i][j]=sum; 
                   4327:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4328:        big=dum; 
                   4329:        imax=i; 
                   4330:       } 
                   4331:     } 
                   4332:     if (j != imax) { 
                   4333:       for (k=1;k<=n;k++) { 
                   4334:        dum=a[imax][k]; 
                   4335:        a[imax][k]=a[j][k]; 
                   4336:        a[j][k]=dum; 
                   4337:       } 
                   4338:       *d = -(*d); 
                   4339:       vv[imax]=vv[j]; 
                   4340:     } 
                   4341:     indx[j]=imax; 
                   4342:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4343:     if (j != n) { 
                   4344:       dum=1.0/(a[j][j]); 
                   4345:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4346:     } 
                   4347:   } 
                   4348:   free_vector(vv,1,n);  /* Doesn't work */
                   4349: ;
                   4350: } 
                   4351: 
                   4352: void lubksb(double **a, int n, int *indx, double b[]) 
                   4353: { 
                   4354:   int i,ii=0,ip,j; 
                   4355:   double sum; 
                   4356:  
                   4357:   for (i=1;i<=n;i++) { 
                   4358:     ip=indx[i]; 
                   4359:     sum=b[ip]; 
                   4360:     b[ip]=b[i]; 
                   4361:     if (ii) 
                   4362:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4363:     else if (sum) ii=i; 
                   4364:     b[i]=sum; 
                   4365:   } 
                   4366:   for (i=n;i>=1;i--) { 
                   4367:     sum=b[i]; 
                   4368:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4369:     b[i]=sum/a[i][i]; 
                   4370:   } 
                   4371: } 
                   4372: 
                   4373: void pstamp(FILE *fichier)
                   4374: {
1.196     brouard  4375:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4376: }
                   4377: 
1.253     brouard  4378: 
                   4379: 
1.126     brouard  4380: /************ Frequencies ********************/
1.251     brouard  4381: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4382:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4383:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4384: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4385:   
1.265     brouard  4386:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4387:   int iind=0, iage=0;
                   4388:   int mi; /* Effective wave */
                   4389:   int first;
                   4390:   double ***freq; /* Frequencies */
1.268     brouard  4391:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4392:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4393:   double *meanq, *stdq, *idq;
1.226     brouard  4394:   double **meanqt;
                   4395:   double *pp, **prop, *posprop, *pospropt;
                   4396:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4397:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4398:   double agebegin, ageend;
                   4399:     
                   4400:   pp=vector(1,nlstate);
1.251     brouard  4401:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4402:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4403:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4404:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4405:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4406:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4407:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4408:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4409:   strcpy(fileresp,"P_");
                   4410:   strcat(fileresp,fileresu);
                   4411:   /*strcat(fileresphtm,fileresu);*/
                   4412:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4413:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4414:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4415:     exit(0);
                   4416:   }
1.240     brouard  4417:   
1.226     brouard  4418:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4419:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4420:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4421:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4422:     fflush(ficlog);
                   4423:     exit(70); 
                   4424:   }
                   4425:   else{
                   4426:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4427: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4428: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4429:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4430:   }
1.237     brouard  4431:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4432:   
1.226     brouard  4433:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4434:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4435:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4436:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4437:     fflush(ficlog);
                   4438:     exit(70); 
1.240     brouard  4439:   } else{
1.226     brouard  4440:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4441: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4442: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4443:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4444:   }
1.240     brouard  4445:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4446:   
1.253     brouard  4447:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4448:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4449:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4450:   j1=0;
1.126     brouard  4451:   
1.227     brouard  4452:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4453:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4454:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4455:   
                   4456:   
1.226     brouard  4457:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4458:      reference=low_education V1=0,V2=0
                   4459:      med_educ                V1=1 V2=0, 
                   4460:      high_educ               V1=0 V2=1
                   4461:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4462:   */
1.249     brouard  4463:   dateintsum=0;
                   4464:   k2cpt=0;
                   4465: 
1.253     brouard  4466:   if(cptcoveff == 0 )
1.265     brouard  4467:     nl=1;  /* Constant and age model only */
1.253     brouard  4468:   else
                   4469:     nl=2;
1.265     brouard  4470: 
                   4471:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4472:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4473:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4474:    *     freq[s1][s2][iage] =0.
                   4475:    *     Loop on iind
                   4476:    *       ++freq[s1][s2][iage] weighted
                   4477:    *     end iind
                   4478:    *     if covariate and j!0
                   4479:    *       headers Variable on one line
                   4480:    *     endif cov j!=0
                   4481:    *     header of frequency table by age
                   4482:    *     Loop on age
                   4483:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4484:    *       pos+=freq[s1][s2][iage] weighted
                   4485:    *       Loop on s1 initial state
                   4486:    *         fprintf(ficresp
                   4487:    *       end s1
                   4488:    *     end age
                   4489:    *     if j!=0 computes starting values
                   4490:    *     end compute starting values
                   4491:    *   end j1
                   4492:    * end nl 
                   4493:    */
1.253     brouard  4494:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4495:     if(nj==1)
                   4496:       j=0;  /* First pass for the constant */
1.265     brouard  4497:     else{
1.253     brouard  4498:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4499:     }
1.251     brouard  4500:     first=1;
1.265     brouard  4501:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4502:       posproptt=0.;
                   4503:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4504:        scanf("%d", i);*/
                   4505:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4506:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4507:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4508:            freq[i][s2][m]=0;
1.251     brouard  4509:       
                   4510:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4511:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4512:          prop[i][m]=0;
                   4513:        posprop[i]=0;
                   4514:        pospropt[i]=0;
                   4515:       }
1.283     brouard  4516:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4517:         idq[z1]=0.;
                   4518:         meanq[z1]=0.;
                   4519:         stdq[z1]=0.;
1.283     brouard  4520:       }
                   4521:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4522:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4523:       /*         meanqt[m][z1]=0.; */
                   4524:       /*       } */
                   4525:       /* }       */
1.251     brouard  4526:       /* dateintsum=0; */
                   4527:       /* k2cpt=0; */
                   4528:       
1.265     brouard  4529:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4530:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4531:        bool=1;
                   4532:        if(j !=0){
                   4533:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4534:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4535:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4536:                /* if(Tvaraff[z1] ==-20){ */
                   4537:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4538:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4539:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4540:                /* }else  */
                   4541:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4542:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4543:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4544:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4545:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4546:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4547:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4548:                } /* Onlyf fixed */
                   4549:              } /* end z1 */
                   4550:            } /* cptcovn > 0 */
                   4551:          } /* end any */
                   4552:        }/* end j==0 */
1.265     brouard  4553:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4554:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4555:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4556:            m=mw[mi][iind];
                   4557:            if(j!=0){
                   4558:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4559:                for (z1=1; z1<=cptcoveff; z1++) {
                   4560:                  if( Fixed[Tmodelind[z1]]==1){
                   4561:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4562:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4563:                                                                                      value is -1, we don't select. It differs from the 
                   4564:                                                                                      constant and age model which counts them. */
                   4565:                      bool=0; /* not selected */
                   4566:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4567:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4568:                      bool=0;
                   4569:                    }
                   4570:                  }
                   4571:                }
                   4572:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4573:            } /* end j==0 */
                   4574:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4575:            if(bool==1){ /*Selected */
1.251     brouard  4576:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4577:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4578:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4579:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4580:              if(m >=firstpass && m <=lastpass){
                   4581:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4582:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4583:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4584:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4585:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4586:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4587:                if (m<lastpass) {
                   4588:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4589:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4590:                  if(s[m][iind]==-1)
                   4591:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4592:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4593:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4594:                    idq[z1]=idq[z1]+weight[iind];
                   4595:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4596:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4597:                  }
1.251     brouard  4598:                  /* if((int)agev[m][iind] == 55) */
                   4599:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4600:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4601:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4602:                }
1.251     brouard  4603:              } /* end if between passes */  
                   4604:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4605:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4606:                k2cpt++;
                   4607:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4608:              }
1.251     brouard  4609:            }else{
                   4610:              bool=1;
                   4611:            }/* end bool 2 */
                   4612:          } /* end m */
1.284     brouard  4613:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4614:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4615:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4616:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4617:          /* } */
1.251     brouard  4618:        } /* end bool */
                   4619:       } /* end iind = 1 to imx */
                   4620:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4621:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4622:       
                   4623:       
                   4624:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4625:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4626:         pstamp(ficresp);
1.251     brouard  4627:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4628:         pstamp(ficresp);
1.251     brouard  4629:        printf( "\n#********** Variable "); 
                   4630:        fprintf(ficresp, "\n#********** Variable "); 
                   4631:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4632:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4633:        fprintf(ficlog, "\n#********** Variable "); 
                   4634:        for (z1=1; z1<=cptcoveff; z1++){
                   4635:          if(!FixedV[Tvaraff[z1]]){
                   4636:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4637:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4638:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4639:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4640:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4641:          }else{
1.251     brouard  4642:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4643:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4644:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4645:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4646:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4647:          }
                   4648:        }
                   4649:        printf( "**********\n#");
                   4650:        fprintf(ficresp, "**********\n#");
                   4651:        fprintf(ficresphtm, "**********</h3>\n");
                   4652:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4653:        fprintf(ficlog, "**********\n");
                   4654:       }
1.284     brouard  4655:       /*
                   4656:        Printing means of quantitative variables if any
                   4657:       */
                   4658:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4659:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4660:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4661:        if(weightopt==1){
                   4662:          printf(" Weighted mean and standard deviation of");
                   4663:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4664:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4665:        }
1.285     brouard  4666:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4667:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4668:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4669:       }
                   4670:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4671:       /*       for(m=1;m<=lastpass;m++){ */
                   4672:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4673:       /*   } */
                   4674:       /* } */
1.283     brouard  4675: 
1.251     brouard  4676:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4677:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4678:         fprintf(ficresp, " Age");
                   4679:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4680:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4681:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4682:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4683:       }
1.265     brouard  4684:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4685:       fprintf(ficresphtm, "\n");
                   4686:       
                   4687:       /* Header of frequency table by age */
                   4688:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4689:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4690:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4691:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4692:          if(s2!=0 && m!=0)
                   4693:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4694:        }
1.226     brouard  4695:       }
1.251     brouard  4696:       fprintf(ficresphtmfr, "\n");
                   4697:     
                   4698:       /* For each age */
                   4699:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4700:        fprintf(ficresphtm,"<tr>");
                   4701:        if(iage==iagemax+1){
                   4702:          fprintf(ficlog,"1");
                   4703:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4704:        }else if(iage==iagemax+2){
                   4705:          fprintf(ficlog,"0");
                   4706:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4707:        }else if(iage==iagemax+3){
                   4708:          fprintf(ficlog,"Total");
                   4709:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4710:        }else{
1.240     brouard  4711:          if(first==1){
1.251     brouard  4712:            first=0;
                   4713:            printf("See log file for details...\n");
                   4714:          }
                   4715:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4716:          fprintf(ficlog,"Age %d", iage);
                   4717:        }
1.265     brouard  4718:        for(s1=1; s1 <=nlstate ; s1++){
                   4719:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4720:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4721:        }
1.265     brouard  4722:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4723:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4724:            pos += freq[s1][m][iage];
                   4725:          if(pp[s1]>=1.e-10){
1.251     brouard  4726:            if(first==1){
1.265     brouard  4727:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4728:            }
1.265     brouard  4729:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4730:          }else{
                   4731:            if(first==1)
1.265     brouard  4732:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4733:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4734:          }
                   4735:        }
                   4736:       
1.265     brouard  4737:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4738:          /* posprop[s1]=0; */
                   4739:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4740:            pp[s1] += freq[s1][m][iage];
                   4741:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4742:       
                   4743:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4744:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4745:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4746:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4747:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4748:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4749:        }
                   4750:        
                   4751:        /* Writing ficresp */
                   4752:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4753:           if( iage <= iagemax){
                   4754:            fprintf(ficresp," %d",iage);
                   4755:           }
                   4756:         }else if( nj==2){
                   4757:           if( iage <= iagemax){
                   4758:            fprintf(ficresp," %d",iage);
                   4759:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4760:           }
1.240     brouard  4761:        }
1.265     brouard  4762:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4763:          if(pos>=1.e-5){
1.251     brouard  4764:            if(first==1)
1.265     brouard  4765:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4766:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4767:          }else{
                   4768:            if(first==1)
1.265     brouard  4769:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4770:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4771:          }
                   4772:          if( iage <= iagemax){
                   4773:            if(pos>=1.e-5){
1.265     brouard  4774:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4775:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4776:               }else if( nj==2){
                   4777:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4778:               }
                   4779:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4780:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4781:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4782:            } else{
                   4783:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4784:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4785:            }
1.240     brouard  4786:          }
1.265     brouard  4787:          pospropt[s1] +=posprop[s1];
                   4788:        } /* end loop s1 */
1.251     brouard  4789:        /* pospropt=0.; */
1.265     brouard  4790:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4791:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4792:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4793:              if(first==1){
1.265     brouard  4794:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4795:              }
1.265     brouard  4796:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4797:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4798:            }
1.265     brouard  4799:            if(s1!=0 && m!=0)
                   4800:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4801:          }
1.265     brouard  4802:        } /* end loop s1 */
1.251     brouard  4803:        posproptt=0.; 
1.265     brouard  4804:        for(s1=1; s1 <=nlstate; s1++){
                   4805:          posproptt += pospropt[s1];
1.251     brouard  4806:        }
                   4807:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4808:        fprintf(ficresphtm,"</tr>\n");
                   4809:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4810:          if(iage <= iagemax)
                   4811:            fprintf(ficresp,"\n");
1.240     brouard  4812:        }
1.251     brouard  4813:        if(first==1)
                   4814:          printf("Others in log...\n");
                   4815:        fprintf(ficlog,"\n");
                   4816:       } /* end loop age iage */
1.265     brouard  4817:       
1.251     brouard  4818:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4819:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4820:        if(posproptt < 1.e-5){
1.265     brouard  4821:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4822:        }else{
1.265     brouard  4823:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4824:        }
1.226     brouard  4825:       }
1.251     brouard  4826:       fprintf(ficresphtm,"</tr>\n");
                   4827:       fprintf(ficresphtm,"</table>\n");
                   4828:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4829:       if(posproptt < 1.e-5){
1.251     brouard  4830:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4831:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4832:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4833:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4834:        invalidvarcomb[j1]=1;
1.226     brouard  4835:       }else{
1.251     brouard  4836:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4837:        invalidvarcomb[j1]=0;
1.226     brouard  4838:       }
1.251     brouard  4839:       fprintf(ficresphtmfr,"</table>\n");
                   4840:       fprintf(ficlog,"\n");
                   4841:       if(j!=0){
                   4842:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4843:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4844:          for(k=1; k <=(nlstate+ndeath); k++){
                   4845:            if (k != i) {
1.265     brouard  4846:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4847:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4848:                  if(j1==1){ /* All dummy covariates to zero */
                   4849:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4850:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4851:                    printf("%d%d ",i,k);
                   4852:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4853:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4854:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4855:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4856:                  }
1.253     brouard  4857:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4858:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4859:                    x[iage]= (double)iage;
                   4860:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4861:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4862:                  }
1.268     brouard  4863:                  /* Some are not finite, but linreg will ignore these ages */
                   4864:                  no=0;
1.253     brouard  4865:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4866:                  pstart[s1]=b;
                   4867:                  pstart[s1-1]=a;
1.252     brouard  4868:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4869:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4870:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4871:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4872:                  printf("%d%d ",i,k);
                   4873:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4874:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4875:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4876:                  ;
                   4877:                }
                   4878:                /* printf("%12.7f )", param[i][jj][k]); */
                   4879:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4880:                s1++; 
1.251     brouard  4881:              } /* end jj */
                   4882:            } /* end k!= i */
                   4883:          } /* end k */
1.265     brouard  4884:        } /* end i, s1 */
1.251     brouard  4885:       } /* end j !=0 */
                   4886:     } /* end selected combination of covariate j1 */
                   4887:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4888:       printf("#Freqsummary: Starting values for the constants:\n");
                   4889:       fprintf(ficlog,"\n");
1.265     brouard  4890:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4891:        for(k=1; k <=(nlstate+ndeath); k++){
                   4892:          if (k != i) {
                   4893:            printf("%d%d ",i,k);
                   4894:            fprintf(ficlog,"%d%d ",i,k);
                   4895:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4896:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4897:              if(jj==1){ /* Age has to be done */
1.265     brouard  4898:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4899:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4900:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4901:              }
                   4902:              /* printf("%12.7f )", param[i][jj][k]); */
                   4903:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4904:              s1++; 
1.250     brouard  4905:            }
1.251     brouard  4906:            printf("\n");
                   4907:            fprintf(ficlog,"\n");
1.250     brouard  4908:          }
                   4909:        }
1.284     brouard  4910:       } /* end of state i */
1.251     brouard  4911:       printf("#Freqsummary\n");
                   4912:       fprintf(ficlog,"\n");
1.265     brouard  4913:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4914:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4915:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4916:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4917:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4918:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4919:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4920:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4921:          /* } */
                   4922:        }
1.265     brouard  4923:       } /* end loop s1 */
1.251     brouard  4924:       
                   4925:       printf("\n");
                   4926:       fprintf(ficlog,"\n");
                   4927:     } /* end j=0 */
1.249     brouard  4928:   } /* end j */
1.252     brouard  4929: 
1.253     brouard  4930:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4931:     for(i=1, jk=1; i <=nlstate; i++){
                   4932:       for(j=1; j <=nlstate+ndeath; j++){
                   4933:        if(j!=i){
                   4934:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4935:          printf("%1d%1d",i,j);
                   4936:          fprintf(ficparo,"%1d%1d",i,j);
                   4937:          for(k=1; k<=ncovmodel;k++){
                   4938:            /*    printf(" %lf",param[i][j][k]); */
                   4939:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4940:            p[jk]=pstart[jk];
                   4941:            printf(" %f ",pstart[jk]);
                   4942:            fprintf(ficparo," %f ",pstart[jk]);
                   4943:            jk++;
                   4944:          }
                   4945:          printf("\n");
                   4946:          fprintf(ficparo,"\n");
                   4947:        }
                   4948:       }
                   4949:     }
                   4950:   } /* end mle=-2 */
1.226     brouard  4951:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4952:   
1.226     brouard  4953:   fclose(ficresp);
                   4954:   fclose(ficresphtm);
                   4955:   fclose(ficresphtmfr);
1.283     brouard  4956:   free_vector(idq,1,nqfveff);
1.226     brouard  4957:   free_vector(meanq,1,nqfveff);
1.284     brouard  4958:   free_vector(stdq,1,nqfveff);
1.226     brouard  4959:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4960:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4961:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4962:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4963:   free_vector(pospropt,1,nlstate);
                   4964:   free_vector(posprop,1,nlstate);
1.251     brouard  4965:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4966:   free_vector(pp,1,nlstate);
                   4967:   /* End of freqsummary */
                   4968: }
1.126     brouard  4969: 
1.268     brouard  4970: /* Simple linear regression */
                   4971: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4972: 
                   4973:   /* y=a+bx regression */
                   4974:   double   sumx = 0.0;                        /* sum of x                      */
                   4975:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4976:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4977:   double   sumy = 0.0;                        /* sum of y                      */
                   4978:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4979:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4980:   double yhat;
                   4981:   
                   4982:   double denom=0;
                   4983:   int i;
                   4984:   int ne=*no;
                   4985:   
                   4986:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4987:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4988:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4989:       continue;
                   4990:     }
                   4991:     ne=ne+1;
                   4992:     sumx  += x[i];       
                   4993:     sumx2 += x[i]*x[i];  
                   4994:     sumxy += x[i] * y[i];
                   4995:     sumy  += y[i];      
                   4996:     sumy2 += y[i]*y[i]; 
                   4997:     denom = (ne * sumx2 - sumx*sumx);
                   4998:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   4999:   } 
                   5000:   
                   5001:   denom = (ne * sumx2 - sumx*sumx);
                   5002:   if (denom == 0) {
                   5003:     // vertical, slope m is infinity
                   5004:     *b = INFINITY;
                   5005:     *a = 0;
                   5006:     if (r) *r = 0;
                   5007:     return 1;
                   5008:   }
                   5009:   
                   5010:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5011:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5012:   if (r!=NULL) {
                   5013:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5014:       sqrt((sumx2 - sumx*sumx/ne) *
                   5015:           (sumy2 - sumy*sumy/ne));
                   5016:   }
                   5017:   *no=ne;
                   5018:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5019:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5020:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5021:       continue;
                   5022:     }
                   5023:     ne=ne+1;
                   5024:     yhat = y[i] - *a -*b* x[i];
                   5025:     sume2  += yhat * yhat ;       
                   5026:     
                   5027:     denom = (ne * sumx2 - sumx*sumx);
                   5028:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5029:   } 
                   5030:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5031:   *sa= *sb * sqrt(sumx2/ne);
                   5032:   
                   5033:   return 0; 
                   5034: }
                   5035: 
1.126     brouard  5036: /************ Prevalence ********************/
1.227     brouard  5037: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5038: {  
                   5039:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5040:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5041:      We still use firstpass and lastpass as another selection.
                   5042:   */
1.126     brouard  5043:  
1.227     brouard  5044:   int i, m, jk, j1, bool, z1,j, iv;
                   5045:   int mi; /* Effective wave */
                   5046:   int iage;
                   5047:   double agebegin, ageend;
                   5048: 
                   5049:   double **prop;
                   5050:   double posprop; 
                   5051:   double  y2; /* in fractional years */
                   5052:   int iagemin, iagemax;
                   5053:   int first; /** to stop verbosity which is redirected to log file */
                   5054: 
                   5055:   iagemin= (int) agemin;
                   5056:   iagemax= (int) agemax;
                   5057:   /*pp=vector(1,nlstate);*/
1.251     brouard  5058:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5059:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5060:   j1=0;
1.222     brouard  5061:   
1.227     brouard  5062:   /*j=cptcoveff;*/
                   5063:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5064:   
1.288   ! brouard  5065:   first=0;
1.227     brouard  5066:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5067:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5068:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5069:        prop[i][iage]=0.0;
                   5070:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5071:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5072:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5073:     
                   5074:     for (i=1; i<=imx; i++) { /* Each individual */
                   5075:       bool=1;
                   5076:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5077:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5078:        m=mw[mi][i];
                   5079:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5080:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5081:        for (z1=1; z1<=cptcoveff; z1++){
                   5082:          if( Fixed[Tmodelind[z1]]==1){
                   5083:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5084:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5085:              bool=0;
                   5086:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5087:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5088:              bool=0;
                   5089:            }
                   5090:        }
                   5091:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5092:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5093:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5094:          if(m >=firstpass && m <=lastpass){
                   5095:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5096:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5097:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5098:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5099:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5100:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5101:                exit(1);
                   5102:              }
                   5103:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5104:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5105:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5106:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5107:              } /* end valid statuses */ 
                   5108:            } /* end selection of dates */
                   5109:          } /* end selection of waves */
                   5110:        } /* end bool */
                   5111:       } /* end wave */
                   5112:     } /* end individual */
                   5113:     for(i=iagemin; i <= iagemax+3; i++){  
                   5114:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5115:        posprop += prop[jk][i]; 
                   5116:       } 
                   5117:       
                   5118:       for(jk=1; jk <=nlstate ; jk++){      
                   5119:        if( i <=  iagemax){ 
                   5120:          if(posprop>=1.e-5){ 
                   5121:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5122:          } else{
1.288   ! brouard  5123:            if(!first){
        !          5124:              first=1;
1.266     brouard  5125:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5126:            }else{
1.288   ! brouard  5127:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5128:            }
                   5129:          }
                   5130:        } 
                   5131:       }/* end jk */ 
                   5132:     }/* end i */ 
1.222     brouard  5133:      /*} *//* end i1 */
1.227     brouard  5134:   } /* end j1 */
1.222     brouard  5135:   
1.227     brouard  5136:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5137:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5138:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5139: }  /* End of prevalence */
1.126     brouard  5140: 
                   5141: /************* Waves Concatenation ***************/
                   5142: 
                   5143: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5144: {
                   5145:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5146:      Death is a valid wave (if date is known).
                   5147:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5148:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5149:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5150:   */
1.126     brouard  5151: 
1.224     brouard  5152:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5153:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5154:      double sum=0., jmean=0.;*/
1.224     brouard  5155:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5156:   int j, k=0,jk, ju, jl;
                   5157:   double sum=0.;
                   5158:   first=0;
1.214     brouard  5159:   firstwo=0;
1.217     brouard  5160:   firsthree=0;
1.218     brouard  5161:   firstfour=0;
1.164     brouard  5162:   jmin=100000;
1.126     brouard  5163:   jmax=-1;
                   5164:   jmean=0.;
1.224     brouard  5165: 
                   5166: /* Treating live states */
1.214     brouard  5167:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5168:     mi=0;  /* First valid wave */
1.227     brouard  5169:     mli=0; /* Last valid wave */
1.126     brouard  5170:     m=firstpass;
1.214     brouard  5171:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5172:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5173:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5174:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5175:        mw[++mi][i]=m;
                   5176:        mli=m;
1.224     brouard  5177:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5178:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5179:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5180:       }
1.227     brouard  5181:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5182: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5183:        break;
1.224     brouard  5184: #else
1.227     brouard  5185:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5186:          if(firsthree == 0){
1.262     brouard  5187:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5188:            firsthree=1;
                   5189:          }
1.262     brouard  5190:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5191:          mw[++mi][i]=m;
                   5192:          mli=m;
                   5193:        }
                   5194:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5195:          nbwarn++;
                   5196:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5197:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5198:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5199:          }
                   5200:          break;
                   5201:        }
                   5202:        break;
1.224     brouard  5203: #endif
1.227     brouard  5204:       }/* End m >= lastpass */
1.126     brouard  5205:     }/* end while */
1.224     brouard  5206: 
1.227     brouard  5207:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5208:     /* After last pass */
1.224     brouard  5209: /* Treating death states */
1.214     brouard  5210:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5211:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5212:       /* } */
1.126     brouard  5213:       mi++;    /* Death is another wave */
                   5214:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5215:       /* Only death is a correct wave */
1.126     brouard  5216:       mw[mi][i]=m;
1.257     brouard  5217:     } /* else not in a death state */
1.224     brouard  5218: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5219:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5220:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5221:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5222:          nbwarn++;
                   5223:          if(firstfiv==0){
                   5224:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5225:            firstfiv=1;
                   5226:          }else{
                   5227:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5228:          }
                   5229:        }else{ /* Death occured afer last wave potential bias */
                   5230:          nberr++;
                   5231:          if(firstwo==0){
1.257     brouard  5232:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5233:            firstwo=1;
                   5234:          }
1.257     brouard  5235:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5236:        }
1.257     brouard  5237:       }else{ /* if date of interview is unknown */
1.227     brouard  5238:        /* death is known but not confirmed by death status at any wave */
                   5239:        if(firstfour==0){
                   5240:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5241:          firstfour=1;
                   5242:        }
                   5243:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5244:       }
1.224     brouard  5245:     } /* end if date of death is known */
                   5246: #endif
                   5247:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5248:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5249:     if(mi==0){
                   5250:       nbwarn++;
                   5251:       if(first==0){
1.227     brouard  5252:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5253:        first=1;
1.126     brouard  5254:       }
                   5255:       if(first==1){
1.227     brouard  5256:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5257:       }
                   5258:     } /* end mi==0 */
                   5259:   } /* End individuals */
1.214     brouard  5260:   /* wav and mw are no more changed */
1.223     brouard  5261:        
1.214     brouard  5262:   
1.126     brouard  5263:   for(i=1; i<=imx; i++){
                   5264:     for(mi=1; mi<wav[i];mi++){
                   5265:       if (stepm <=0)
1.227     brouard  5266:        dh[mi][i]=1;
1.126     brouard  5267:       else{
1.260     brouard  5268:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5269:          if (agedc[i] < 2*AGESUP) {
                   5270:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5271:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5272:            else if(j<0){
                   5273:              nberr++;
                   5274:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5275:              j=1; /* Temporary Dangerous patch */
                   5276:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5277:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5278:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5279:            }
                   5280:            k=k+1;
                   5281:            if (j >= jmax){
                   5282:              jmax=j;
                   5283:              ijmax=i;
                   5284:            }
                   5285:            if (j <= jmin){
                   5286:              jmin=j;
                   5287:              ijmin=i;
                   5288:            }
                   5289:            sum=sum+j;
                   5290:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5291:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5292:          }
                   5293:        }
                   5294:        else{
                   5295:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5296: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5297:                                        
1.227     brouard  5298:          k=k+1;
                   5299:          if (j >= jmax) {
                   5300:            jmax=j;
                   5301:            ijmax=i;
                   5302:          }
                   5303:          else if (j <= jmin){
                   5304:            jmin=j;
                   5305:            ijmin=i;
                   5306:          }
                   5307:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5308:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5309:          if(j<0){
                   5310:            nberr++;
                   5311:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5312:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5313:          }
                   5314:          sum=sum+j;
                   5315:        }
                   5316:        jk= j/stepm;
                   5317:        jl= j -jk*stepm;
                   5318:        ju= j -(jk+1)*stepm;
                   5319:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5320:          if(jl==0){
                   5321:            dh[mi][i]=jk;
                   5322:            bh[mi][i]=0;
                   5323:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5324:                  * to avoid the price of an extra matrix product in likelihood */
                   5325:            dh[mi][i]=jk+1;
                   5326:            bh[mi][i]=ju;
                   5327:          }
                   5328:        }else{
                   5329:          if(jl <= -ju){
                   5330:            dh[mi][i]=jk;
                   5331:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5332:                                 * is higher than the multiple of stepm and negative otherwise.
                   5333:                                 */
                   5334:          }
                   5335:          else{
                   5336:            dh[mi][i]=jk+1;
                   5337:            bh[mi][i]=ju;
                   5338:          }
                   5339:          if(dh[mi][i]==0){
                   5340:            dh[mi][i]=1; /* At least one step */
                   5341:            bh[mi][i]=ju; /* At least one step */
                   5342:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5343:          }
                   5344:        } /* end if mle */
1.126     brouard  5345:       }
                   5346:     } /* end wave */
                   5347:   }
                   5348:   jmean=sum/k;
                   5349:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5350:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5351: }
1.126     brouard  5352: 
                   5353: /*********** Tricode ****************************/
1.220     brouard  5354:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5355:  {
                   5356:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5357:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5358:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5359:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5360:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5361:     */
1.130     brouard  5362: 
1.242     brouard  5363:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5364:    int modmaxcovj=0; /* Modality max of covariates j */
                   5365:    int cptcode=0; /* Modality max of covariates j */
                   5366:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5367: 
                   5368: 
1.242     brouard  5369:    /* cptcoveff=0;  */
                   5370:    /* *cptcov=0; */
1.126     brouard  5371:  
1.242     brouard  5372:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5373:    for (k=1; k <= maxncov; k++)
                   5374:      for(j=1; j<=2; j++)
                   5375:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5376: 
1.242     brouard  5377:    /* Loop on covariates without age and products and no quantitative variable */
                   5378:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5379:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5380:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5381:        switch(Fixed[k]) {
                   5382:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5383:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5384:           ij=(int)(covar[Tvar[k]][i]);
                   5385:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5386:            * If product of Vn*Vm, still boolean *:
                   5387:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5388:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5389:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5390:              modality of the nth covariate of individual i. */
                   5391:           if (ij > modmaxcovj)
                   5392:             modmaxcovj=ij; 
                   5393:           else if (ij < modmincovj) 
                   5394:             modmincovj=ij; 
1.287     brouard  5395:           if (ij <0 || ij >1 ){
                   5396:             printf("Information, IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5397:             fprintf(ficlog,"Information, currently IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5398:           }
                   5399:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5400:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5401:             exit(1);
                   5402:           }else
                   5403:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5404:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5405:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5406:           /* getting the maximum value of the modality of the covariate
                   5407:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5408:              female ies 1, then modmaxcovj=1.
                   5409:           */
                   5410:         } /* end for loop on individuals i */
                   5411:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5412:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5413:         cptcode=modmaxcovj;
                   5414:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5415:         /*for (i=0; i<=cptcode; i++) {*/
                   5416:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5417:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5418:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5419:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5420:             if( j != -1){
                   5421:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5422:                                  covariate for which somebody answered excluding 
                   5423:                                  undefined. Usually 2: 0 and 1. */
                   5424:             }
                   5425:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5426:                                     covariate for which somebody answered including 
                   5427:                                     undefined. Usually 3: -1, 0 and 1. */
                   5428:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5429:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5430:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5431:                        
1.242     brouard  5432:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5433:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5434:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5435:         /* modmincovj=3; modmaxcovj = 7; */
                   5436:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5437:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5438:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5439:         /* nbcode[Tvar[j]][ij]=k; */
                   5440:         /* nbcode[Tvar[j]][1]=0; */
                   5441:         /* nbcode[Tvar[j]][2]=1; */
                   5442:         /* nbcode[Tvar[j]][3]=2; */
                   5443:         /* To be continued (not working yet). */
                   5444:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5445: 
                   5446:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5447:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5448:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5449:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5450:         /*, could be restored in the future */
                   5451:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5452:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5453:             break;
                   5454:           }
                   5455:           ij++;
1.287     brouard  5456:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5457:           cptcode = ij; /* New max modality for covar j */
                   5458:         } /* end of loop on modality i=-1 to 1 or more */
                   5459:         break;
                   5460:        case 1: /* Testing on varying covariate, could be simple and
                   5461:                * should look at waves or product of fixed *
                   5462:                * varying. No time to test -1, assuming 0 and 1 only */
                   5463:         ij=0;
                   5464:         for(i=0; i<=1;i++){
                   5465:           nbcode[Tvar[k]][++ij]=i;
                   5466:         }
                   5467:         break;
                   5468:        default:
                   5469:         break;
                   5470:        } /* end switch */
                   5471:      } /* end dummy test */
1.287     brouard  5472:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5473:   
                   5474:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5475:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5476:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5477:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5478:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5479:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5480:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5481:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5482:   
                   5483:    ij=0;
                   5484:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5485:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5486:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5487:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5488:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5489:        /* If product not in single variable we don't print results */
                   5490:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5491:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5492:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5493:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5494:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5495:        if(Fixed[k]!=0)
                   5496:         anyvaryingduminmodel=1;
                   5497:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5498:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5499:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5500:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5501:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5502:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5503:      } 
                   5504:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5505:    /* ij--; */
                   5506:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5507:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5508:                * because they can be excluded from the model and real
                   5509:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5510:    for(j=ij+1; j<= cptcovt; j++){
                   5511:      Tvaraff[j]=0;
                   5512:      Tmodelind[j]=0;
                   5513:    }
                   5514:    for(j=ntveff+1; j<= cptcovt; j++){
                   5515:      TmodelInvind[j]=0;
                   5516:    }
                   5517:    /* To be sorted */
                   5518:    ;
                   5519:  }
1.126     brouard  5520: 
1.145     brouard  5521: 
1.126     brouard  5522: /*********** Health Expectancies ****************/
                   5523: 
1.235     brouard  5524:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5525: 
                   5526: {
                   5527:   /* Health expectancies, no variances */
1.164     brouard  5528:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5529:   int nhstepma, nstepma; /* Decreasing with age */
                   5530:   double age, agelim, hf;
                   5531:   double ***p3mat;
                   5532:   double eip;
                   5533: 
1.238     brouard  5534:   /* pstamp(ficreseij); */
1.126     brouard  5535:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5536:   fprintf(ficreseij,"# Age");
                   5537:   for(i=1; i<=nlstate;i++){
                   5538:     for(j=1; j<=nlstate;j++){
                   5539:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5540:     }
                   5541:     fprintf(ficreseij," e%1d. ",i);
                   5542:   }
                   5543:   fprintf(ficreseij,"\n");
                   5544: 
                   5545:   
                   5546:   if(estepm < stepm){
                   5547:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5548:   }
                   5549:   else  hstepm=estepm;   
                   5550:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5551:    * This is mainly to measure the difference between two models: for example
                   5552:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5553:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5554:    * progression in between and thus overestimating or underestimating according
                   5555:    * to the curvature of the survival function. If, for the same date, we 
                   5556:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5557:    * to compare the new estimate of Life expectancy with the same linear 
                   5558:    * hypothesis. A more precise result, taking into account a more precise
                   5559:    * curvature will be obtained if estepm is as small as stepm. */
                   5560: 
                   5561:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5562:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5563:      nhstepm is the number of hstepm from age to agelim 
                   5564:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5565:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5566:      and note for a fixed period like estepm months */
                   5567:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5568:      survival function given by stepm (the optimization length). Unfortunately it
                   5569:      means that if the survival funtion is printed only each two years of age and if
                   5570:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5571:      results. So we changed our mind and took the option of the best precision.
                   5572:   */
                   5573:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5574: 
                   5575:   agelim=AGESUP;
                   5576:   /* If stepm=6 months */
                   5577:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5578:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5579:     
                   5580: /* nhstepm age range expressed in number of stepm */
                   5581:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5582:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5583:   /* if (stepm >= YEARM) hstepm=1;*/
                   5584:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5585:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5586: 
                   5587:   for (age=bage; age<=fage; age ++){ 
                   5588:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5589:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5590:     /* if (stepm >= YEARM) hstepm=1;*/
                   5591:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5592: 
                   5593:     /* If stepm=6 months */
                   5594:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5595:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5596:     
1.235     brouard  5597:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5598:     
                   5599:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5600:     
                   5601:     printf("%d|",(int)age);fflush(stdout);
                   5602:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5603:     
                   5604:     /* Computing expectancies */
                   5605:     for(i=1; i<=nlstate;i++)
                   5606:       for(j=1; j<=nlstate;j++)
                   5607:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5608:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5609:          
                   5610:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5611: 
                   5612:        }
                   5613: 
                   5614:     fprintf(ficreseij,"%3.0f",age );
                   5615:     for(i=1; i<=nlstate;i++){
                   5616:       eip=0;
                   5617:       for(j=1; j<=nlstate;j++){
                   5618:        eip +=eij[i][j][(int)age];
                   5619:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5620:       }
                   5621:       fprintf(ficreseij,"%9.4f", eip );
                   5622:     }
                   5623:     fprintf(ficreseij,"\n");
                   5624:     
                   5625:   }
                   5626:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5627:   printf("\n");
                   5628:   fprintf(ficlog,"\n");
                   5629:   
                   5630: }
                   5631: 
1.235     brouard  5632:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5633: 
                   5634: {
                   5635:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5636:      to initial status i, ei. .
1.126     brouard  5637:   */
                   5638:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5639:   int nhstepma, nstepma; /* Decreasing with age */
                   5640:   double age, agelim, hf;
                   5641:   double ***p3matp, ***p3matm, ***varhe;
                   5642:   double **dnewm,**doldm;
                   5643:   double *xp, *xm;
                   5644:   double **gp, **gm;
                   5645:   double ***gradg, ***trgradg;
                   5646:   int theta;
                   5647: 
                   5648:   double eip, vip;
                   5649: 
                   5650:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5651:   xp=vector(1,npar);
                   5652:   xm=vector(1,npar);
                   5653:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5654:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5655:   
                   5656:   pstamp(ficresstdeij);
                   5657:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5658:   fprintf(ficresstdeij,"# Age");
                   5659:   for(i=1; i<=nlstate;i++){
                   5660:     for(j=1; j<=nlstate;j++)
                   5661:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5662:     fprintf(ficresstdeij," e%1d. ",i);
                   5663:   }
                   5664:   fprintf(ficresstdeij,"\n");
                   5665: 
                   5666:   pstamp(ficrescveij);
                   5667:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5668:   fprintf(ficrescveij,"# Age");
                   5669:   for(i=1; i<=nlstate;i++)
                   5670:     for(j=1; j<=nlstate;j++){
                   5671:       cptj= (j-1)*nlstate+i;
                   5672:       for(i2=1; i2<=nlstate;i2++)
                   5673:        for(j2=1; j2<=nlstate;j2++){
                   5674:          cptj2= (j2-1)*nlstate+i2;
                   5675:          if(cptj2 <= cptj)
                   5676:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5677:        }
                   5678:     }
                   5679:   fprintf(ficrescveij,"\n");
                   5680:   
                   5681:   if(estepm < stepm){
                   5682:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5683:   }
                   5684:   else  hstepm=estepm;   
                   5685:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5686:    * This is mainly to measure the difference between two models: for example
                   5687:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5688:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5689:    * progression in between and thus overestimating or underestimating according
                   5690:    * to the curvature of the survival function. If, for the same date, we 
                   5691:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5692:    * to compare the new estimate of Life expectancy with the same linear 
                   5693:    * hypothesis. A more precise result, taking into account a more precise
                   5694:    * curvature will be obtained if estepm is as small as stepm. */
                   5695: 
                   5696:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5697:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5698:      nhstepm is the number of hstepm from age to agelim 
                   5699:      nstepm is the number of stepm from age to agelin. 
                   5700:      Look at hpijx to understand the reason of that which relies in memory size
                   5701:      and note for a fixed period like estepm months */
                   5702:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5703:      survival function given by stepm (the optimization length). Unfortunately it
                   5704:      means that if the survival funtion is printed only each two years of age and if
                   5705:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5706:      results. So we changed our mind and took the option of the best precision.
                   5707:   */
                   5708:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5709: 
                   5710:   /* If stepm=6 months */
                   5711:   /* nhstepm age range expressed in number of stepm */
                   5712:   agelim=AGESUP;
                   5713:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5714:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5715:   /* if (stepm >= YEARM) hstepm=1;*/
                   5716:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5717:   
                   5718:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5719:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5720:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5721:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5722:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5723:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5724: 
                   5725:   for (age=bage; age<=fage; age ++){ 
                   5726:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5727:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5728:     /* if (stepm >= YEARM) hstepm=1;*/
                   5729:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5730:                
1.126     brouard  5731:     /* If stepm=6 months */
                   5732:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5733:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5734:     
                   5735:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5736:                
1.126     brouard  5737:     /* Computing  Variances of health expectancies */
                   5738:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5739:        decrease memory allocation */
                   5740:     for(theta=1; theta <=npar; theta++){
                   5741:       for(i=1; i<=npar; i++){ 
1.222     brouard  5742:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5743:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5744:       }
1.235     brouard  5745:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5746:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5747:                        
1.126     brouard  5748:       for(j=1; j<= nlstate; j++){
1.222     brouard  5749:        for(i=1; i<=nlstate; i++){
                   5750:          for(h=0; h<=nhstepm-1; h++){
                   5751:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5752:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5753:          }
                   5754:        }
1.126     brouard  5755:       }
1.218     brouard  5756:                        
1.126     brouard  5757:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5758:        for(h=0; h<=nhstepm-1; h++){
                   5759:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5760:        }
1.126     brouard  5761:     }/* End theta */
                   5762:     
                   5763:     
                   5764:     for(h=0; h<=nhstepm-1; h++)
                   5765:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5766:        for(theta=1; theta <=npar; theta++)
                   5767:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5768:     
1.218     brouard  5769:                
1.222     brouard  5770:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5771:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5772:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5773:                
1.222     brouard  5774:     printf("%d|",(int)age);fflush(stdout);
                   5775:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5776:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5777:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5778:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5779:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5780:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5781:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5782:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5783:       }
                   5784:     }
1.218     brouard  5785:                
1.126     brouard  5786:     /* Computing expectancies */
1.235     brouard  5787:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5788:     for(i=1; i<=nlstate;i++)
                   5789:       for(j=1; j<=nlstate;j++)
1.222     brouard  5790:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5791:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5792:                                        
1.222     brouard  5793:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5794:                                        
1.222     brouard  5795:        }
1.269     brouard  5796: 
                   5797:     /* Standard deviation of expectancies ij */                
1.126     brouard  5798:     fprintf(ficresstdeij,"%3.0f",age );
                   5799:     for(i=1; i<=nlstate;i++){
                   5800:       eip=0.;
                   5801:       vip=0.;
                   5802:       for(j=1; j<=nlstate;j++){
1.222     brouard  5803:        eip += eij[i][j][(int)age];
                   5804:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5805:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5806:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5807:       }
                   5808:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5809:     }
                   5810:     fprintf(ficresstdeij,"\n");
1.218     brouard  5811:                
1.269     brouard  5812:     /* Variance of expectancies ij */          
1.126     brouard  5813:     fprintf(ficrescveij,"%3.0f",age );
                   5814:     for(i=1; i<=nlstate;i++)
                   5815:       for(j=1; j<=nlstate;j++){
1.222     brouard  5816:        cptj= (j-1)*nlstate+i;
                   5817:        for(i2=1; i2<=nlstate;i2++)
                   5818:          for(j2=1; j2<=nlstate;j2++){
                   5819:            cptj2= (j2-1)*nlstate+i2;
                   5820:            if(cptj2 <= cptj)
                   5821:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5822:          }
1.126     brouard  5823:       }
                   5824:     fprintf(ficrescveij,"\n");
1.218     brouard  5825:                
1.126     brouard  5826:   }
                   5827:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5828:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5829:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5830:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5831:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5832:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5833:   printf("\n");
                   5834:   fprintf(ficlog,"\n");
1.218     brouard  5835:        
1.126     brouard  5836:   free_vector(xm,1,npar);
                   5837:   free_vector(xp,1,npar);
                   5838:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5839:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5840:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5841: }
1.218     brouard  5842:  
1.126     brouard  5843: /************ Variance ******************/
1.235     brouard  5844:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5845:  {
1.279     brouard  5846:    /** Variance of health expectancies 
                   5847:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5848:     * double **newm;
                   5849:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5850:     */
1.218     brouard  5851:   
                   5852:    /* int movingaverage(); */
                   5853:    double **dnewm,**doldm;
                   5854:    double **dnewmp,**doldmp;
                   5855:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288   ! brouard  5856:    int first=0;
1.218     brouard  5857:    int k;
                   5858:    double *xp;
1.279     brouard  5859:    double **gp, **gm;  /**< for var eij */
                   5860:    double ***gradg, ***trgradg; /**< for var eij */
                   5861:    double **gradgp, **trgradgp; /**< for var p point j */
                   5862:    double *gpp, *gmp; /**< for var p point j */
                   5863:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5864:    double ***p3mat;
                   5865:    double age,agelim, hf;
                   5866:    /* double ***mobaverage; */
                   5867:    int theta;
                   5868:    char digit[4];
                   5869:    char digitp[25];
                   5870: 
                   5871:    char fileresprobmorprev[FILENAMELENGTH];
                   5872: 
                   5873:    if(popbased==1){
                   5874:      if(mobilav!=0)
                   5875:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5876:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5877:    }
                   5878:    else 
                   5879:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5880: 
1.218     brouard  5881:    /* if (mobilav!=0) { */
                   5882:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5883:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5884:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5885:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5886:    /*   } */
                   5887:    /* } */
                   5888: 
                   5889:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5890:    sprintf(digit,"%-d",ij);
                   5891:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5892:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5893:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5894:    strcat(fileresprobmorprev,fileresu);
                   5895:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5896:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5897:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5898:    }
                   5899:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5900:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5901:    pstamp(ficresprobmorprev);
                   5902:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5903:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5904:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5905:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5906:    }
                   5907:    for(j=1;j<=cptcoveff;j++) 
                   5908:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5909:    fprintf(ficresprobmorprev,"\n");
                   5910: 
1.218     brouard  5911:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5912:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5913:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5914:      for(i=1; i<=nlstate;i++)
                   5915:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5916:    }  
                   5917:    fprintf(ficresprobmorprev,"\n");
                   5918:   
                   5919:    fprintf(ficgp,"\n# Routine varevsij");
                   5920:    fprintf(ficgp,"\nunset title \n");
                   5921:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5922:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5923:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5924: 
1.218     brouard  5925:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5926:    pstamp(ficresvij);
                   5927:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5928:    if(popbased==1)
                   5929:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5930:    else
                   5931:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5932:    fprintf(ficresvij,"# Age");
                   5933:    for(i=1; i<=nlstate;i++)
                   5934:      for(j=1; j<=nlstate;j++)
                   5935:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5936:    fprintf(ficresvij,"\n");
                   5937: 
                   5938:    xp=vector(1,npar);
                   5939:    dnewm=matrix(1,nlstate,1,npar);
                   5940:    doldm=matrix(1,nlstate,1,nlstate);
                   5941:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5942:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5943: 
                   5944:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5945:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5946:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5947:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5948:   
1.218     brouard  5949:    if(estepm < stepm){
                   5950:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5951:    }
                   5952:    else  hstepm=estepm;   
                   5953:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5954:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5955:       nhstepm is the number of hstepm from age to agelim 
                   5956:       nstepm is the number of stepm from age to agelim. 
                   5957:       Look at function hpijx to understand why because of memory size limitations, 
                   5958:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5959:       survival function given by stepm (the optimization length). Unfortunately it
                   5960:       means that if the survival funtion is printed every two years of age and if
                   5961:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5962:       results. So we changed our mind and took the option of the best precision.
                   5963:    */
                   5964:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5965:    agelim = AGESUP;
                   5966:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5967:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5968:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5969:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5970:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5971:      gp=matrix(0,nhstepm,1,nlstate);
                   5972:      gm=matrix(0,nhstepm,1,nlstate);
                   5973:                
                   5974:                
                   5975:      for(theta=1; theta <=npar; theta++){
                   5976:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5977:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5978:        }
1.279     brouard  5979:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   5980:        * returns into prlim .
1.288   ! brouard  5981:        */
1.242     brouard  5982:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  5983: 
                   5984:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  5985:        if (popbased==1) {
                   5986:         if(mobilav ==0){
                   5987:           for(i=1; i<=nlstate;i++)
                   5988:             prlim[i][i]=probs[(int)age][i][ij];
                   5989:         }else{ /* mobilav */ 
                   5990:           for(i=1; i<=nlstate;i++)
                   5991:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5992:         }
                   5993:        }
1.279     brouard  5994:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}_x\f$ at horizon h.
                   5995:        */                      
                   5996:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
                   5997:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}_x\f$, which are the probability
                   5998:        * at horizon h in state j including mortality.
                   5999:        */
1.218     brouard  6000:        for(j=1; j<= nlstate; j++){
                   6001:         for(h=0; h<=nhstepm; h++){
                   6002:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6003:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6004:         }
                   6005:        }
1.279     brouard  6006:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6007:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6008:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6009:        */
                   6010:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6011:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6012:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6013:        }
                   6014:        
                   6015:        /* Again with minus shift */
1.218     brouard  6016:                        
                   6017:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6018:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288   ! brouard  6019: 
1.242     brouard  6020:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6021:                        
                   6022:        if (popbased==1) {
                   6023:         if(mobilav ==0){
                   6024:           for(i=1; i<=nlstate;i++)
                   6025:             prlim[i][i]=probs[(int)age][i][ij];
                   6026:         }else{ /* mobilav */ 
                   6027:           for(i=1; i<=nlstate;i++)
                   6028:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6029:         }
                   6030:        }
                   6031:                        
1.235     brouard  6032:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6033:                        
                   6034:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6035:         for(h=0; h<=nhstepm; h++){
                   6036:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6037:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6038:         }
                   6039:        }
                   6040:        /* This for computing probability of death (h=1 means
                   6041:          computed over hstepm matrices product = hstepm*stepm months) 
                   6042:          as a weighted average of prlim.
                   6043:        */
                   6044:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6045:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6046:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6047:        }    
1.279     brouard  6048:        /* end shifting computations */
                   6049: 
                   6050:        /**< Computing gradient matrix at horizon h 
                   6051:        */
1.218     brouard  6052:        for(j=1; j<= nlstate; j++) /* vareij */
                   6053:         for(h=0; h<=nhstepm; h++){
                   6054:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6055:         }
1.279     brouard  6056:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6057:        */
                   6058:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6059:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6060:        }
                   6061:                        
                   6062:      } /* End theta */
1.279     brouard  6063:      
                   6064:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6065:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6066:                
                   6067:      for(h=0; h<=nhstepm; h++) /* veij */
                   6068:        for(j=1; j<=nlstate;j++)
                   6069:         for(theta=1; theta <=npar; theta++)
                   6070:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6071:                
                   6072:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6073:        for(theta=1; theta <=npar; theta++)
                   6074:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6075:      /**< as well as its transposed matrix 
                   6076:       */               
1.218     brouard  6077:                
                   6078:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6079:      for(i=1;i<=nlstate;i++)
                   6080:        for(j=1;j<=nlstate;j++)
                   6081:         vareij[i][j][(int)age] =0.;
1.279     brouard  6082: 
                   6083:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6084:       * and k (nhstepm) formula 15 of article
                   6085:       * Lievre-Brouard-Heathcote
                   6086:       */
                   6087:      
1.218     brouard  6088:      for(h=0;h<=nhstepm;h++){
                   6089:        for(k=0;k<=nhstepm;k++){
                   6090:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6091:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6092:         for(i=1;i<=nlstate;i++)
                   6093:           for(j=1;j<=nlstate;j++)
                   6094:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6095:        }
                   6096:      }
                   6097:                
1.279     brouard  6098:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6099:       * p.j overall mortality formula 49 but computed directly because
                   6100:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6101:       * wix is independent of theta.
                   6102:       */
1.218     brouard  6103:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6104:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6105:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6106:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6107:         varppt[j][i]=doldmp[j][i];
                   6108:      /* end ppptj */
                   6109:      /*  x centered again */
                   6110:                
1.242     brouard  6111:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6112:                
                   6113:      if (popbased==1) {
                   6114:        if(mobilav ==0){
                   6115:         for(i=1; i<=nlstate;i++)
                   6116:           prlim[i][i]=probs[(int)age][i][ij];
                   6117:        }else{ /* mobilav */ 
                   6118:         for(i=1; i<=nlstate;i++)
                   6119:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6120:        }
                   6121:      }
                   6122:                
                   6123:      /* This for computing probability of death (h=1 means
                   6124:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6125:        as a weighted average of prlim.
                   6126:      */
1.235     brouard  6127:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6128:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6129:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6130:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6131:      }    
                   6132:      /* end probability of death */
                   6133:                
                   6134:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6135:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6136:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6137:        for(i=1; i<=nlstate;i++){
                   6138:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6139:        }
                   6140:      } 
                   6141:      fprintf(ficresprobmorprev,"\n");
                   6142:                
                   6143:      fprintf(ficresvij,"%.0f ",age );
                   6144:      for(i=1; i<=nlstate;i++)
                   6145:        for(j=1; j<=nlstate;j++){
                   6146:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6147:        }
                   6148:      fprintf(ficresvij,"\n");
                   6149:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6150:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6151:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6152:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6153:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6154:    } /* End age */
                   6155:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6156:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6157:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6158:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6159:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6160:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6161:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6162:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6163:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6164:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6165:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6166:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6167:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6168:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6169:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6170:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6171:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6172:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6173:     */
1.218     brouard  6174:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6175:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6176: 
1.218     brouard  6177:    free_vector(xp,1,npar);
                   6178:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6179:    free_matrix(dnewm,1,nlstate,1,npar);
                   6180:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6181:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6182:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6183:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6184:    fclose(ficresprobmorprev);
                   6185:    fflush(ficgp);
                   6186:    fflush(fichtm); 
                   6187:  }  /* end varevsij */
1.126     brouard  6188: 
                   6189: /************ Variance of prevlim ******************/
1.269     brouard  6190:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6191: {
1.205     brouard  6192:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6193:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6194: 
1.268     brouard  6195:   double **dnewmpar,**doldm;
1.126     brouard  6196:   int i, j, nhstepm, hstepm;
                   6197:   double *xp;
                   6198:   double *gp, *gm;
                   6199:   double **gradg, **trgradg;
1.208     brouard  6200:   double **mgm, **mgp;
1.126     brouard  6201:   double age,agelim;
                   6202:   int theta;
                   6203:   
                   6204:   pstamp(ficresvpl);
1.288   ! brouard  6205:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6206:   fprintf(ficresvpl,"# Age ");
                   6207:   if(nresult >=1)
                   6208:     fprintf(ficresvpl," Result# ");
1.126     brouard  6209:   for(i=1; i<=nlstate;i++)
                   6210:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6211:   fprintf(ficresvpl,"\n");
                   6212: 
                   6213:   xp=vector(1,npar);
1.268     brouard  6214:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6215:   doldm=matrix(1,nlstate,1,nlstate);
                   6216:   
                   6217:   hstepm=1*YEARM; /* Every year of age */
                   6218:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6219:   agelim = AGESUP;
                   6220:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6221:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6222:     if (stepm >= YEARM) hstepm=1;
                   6223:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6224:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6225:     mgp=matrix(1,npar,1,nlstate);
                   6226:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6227:     gp=vector(1,nlstate);
                   6228:     gm=vector(1,nlstate);
                   6229: 
                   6230:     for(theta=1; theta <=npar; theta++){
                   6231:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6232:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6233:       }
1.288   ! brouard  6234:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
        !          6235:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
        !          6236:       /* else */
        !          6237:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6238:       for(i=1;i<=nlstate;i++){
1.126     brouard  6239:        gp[i] = prlim[i][i];
1.208     brouard  6240:        mgp[theta][i] = prlim[i][i];
                   6241:       }
1.126     brouard  6242:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6243:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288   ! brouard  6244:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
        !          6245:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
        !          6246:       /* else */
        !          6247:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6248:       for(i=1;i<=nlstate;i++){
1.126     brouard  6249:        gm[i] = prlim[i][i];
1.208     brouard  6250:        mgm[theta][i] = prlim[i][i];
                   6251:       }
1.126     brouard  6252:       for(i=1;i<=nlstate;i++)
                   6253:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6254:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6255:     } /* End theta */
                   6256: 
                   6257:     trgradg =matrix(1,nlstate,1,npar);
                   6258: 
                   6259:     for(j=1; j<=nlstate;j++)
                   6260:       for(theta=1; theta <=npar; theta++)
                   6261:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6262:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6263:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6264:     /*   for(j=1; j<=nlstate;j++){ */
                   6265:     /*         printf(" %d ",j); */
                   6266:     /*         for(theta=1; theta <=npar; theta++) */
                   6267:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6268:     /*         printf("\n "); */
                   6269:     /*   } */
                   6270:     /* } */
                   6271:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6272:     /*   printf("\n gradg %d ",(int)age); */
                   6273:     /*   for(j=1; j<=nlstate;j++){ */
                   6274:     /*         printf("%d ",j); */
                   6275:     /*         for(theta=1; theta <=npar; theta++) */
                   6276:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6277:     /*         printf("\n "); */
                   6278:     /*   } */
                   6279:     /* } */
1.126     brouard  6280: 
                   6281:     for(i=1;i<=nlstate;i++)
                   6282:       varpl[i][(int)age] =0.;
1.209     brouard  6283:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6284:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6285:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6286:     }else{
1.268     brouard  6287:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6288:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6289:     }
1.126     brouard  6290:     for(i=1;i<=nlstate;i++)
                   6291:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6292: 
                   6293:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6294:     if(nresult >=1)
                   6295:       fprintf(ficresvpl,"%d ",nres );
1.288   ! brouard  6296:     for(i=1; i<=nlstate;i++){
1.126     brouard  6297:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288   ! brouard  6298:       /* for(j=1;j<=nlstate;j++) */
        !          6299:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
        !          6300:     }
1.126     brouard  6301:     fprintf(ficresvpl,"\n");
                   6302:     free_vector(gp,1,nlstate);
                   6303:     free_vector(gm,1,nlstate);
1.208     brouard  6304:     free_matrix(mgm,1,npar,1,nlstate);
                   6305:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6306:     free_matrix(gradg,1,npar,1,nlstate);
                   6307:     free_matrix(trgradg,1,nlstate,1,npar);
                   6308:   } /* End age */
                   6309: 
                   6310:   free_vector(xp,1,npar);
                   6311:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6312:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6313: 
                   6314: }
                   6315: 
                   6316: 
                   6317: /************ Variance of backprevalence limit ******************/
1.269     brouard  6318:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6319: {
                   6320:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6321:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6322: 
                   6323:   double **dnewmpar,**doldm;
                   6324:   int i, j, nhstepm, hstepm;
                   6325:   double *xp;
                   6326:   double *gp, *gm;
                   6327:   double **gradg, **trgradg;
                   6328:   double **mgm, **mgp;
                   6329:   double age,agelim;
                   6330:   int theta;
                   6331:   
                   6332:   pstamp(ficresvbl);
                   6333:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6334:   fprintf(ficresvbl,"# Age ");
                   6335:   if(nresult >=1)
                   6336:     fprintf(ficresvbl," Result# ");
                   6337:   for(i=1; i<=nlstate;i++)
                   6338:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6339:   fprintf(ficresvbl,"\n");
                   6340: 
                   6341:   xp=vector(1,npar);
                   6342:   dnewmpar=matrix(1,nlstate,1,npar);
                   6343:   doldm=matrix(1,nlstate,1,nlstate);
                   6344:   
                   6345:   hstepm=1*YEARM; /* Every year of age */
                   6346:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6347:   agelim = AGEINF;
                   6348:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6349:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6350:     if (stepm >= YEARM) hstepm=1;
                   6351:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6352:     gradg=matrix(1,npar,1,nlstate);
                   6353:     mgp=matrix(1,npar,1,nlstate);
                   6354:     mgm=matrix(1,npar,1,nlstate);
                   6355:     gp=vector(1,nlstate);
                   6356:     gm=vector(1,nlstate);
                   6357: 
                   6358:     for(theta=1; theta <=npar; theta++){
                   6359:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6360:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6361:       }
                   6362:       if(mobilavproj > 0 )
                   6363:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6364:       else
                   6365:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6366:       for(i=1;i<=nlstate;i++){
                   6367:        gp[i] = bprlim[i][i];
                   6368:        mgp[theta][i] = bprlim[i][i];
                   6369:       }
                   6370:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6371:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6372:        if(mobilavproj > 0 )
                   6373:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6374:        else
                   6375:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6376:       for(i=1;i<=nlstate;i++){
                   6377:        gm[i] = bprlim[i][i];
                   6378:        mgm[theta][i] = bprlim[i][i];
                   6379:       }
                   6380:       for(i=1;i<=nlstate;i++)
                   6381:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6382:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6383:     } /* End theta */
                   6384: 
                   6385:     trgradg =matrix(1,nlstate,1,npar);
                   6386: 
                   6387:     for(j=1; j<=nlstate;j++)
                   6388:       for(theta=1; theta <=npar; theta++)
                   6389:        trgradg[j][theta]=gradg[theta][j];
                   6390:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6391:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6392:     /*   for(j=1; j<=nlstate;j++){ */
                   6393:     /*         printf(" %d ",j); */
                   6394:     /*         for(theta=1; theta <=npar; theta++) */
                   6395:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6396:     /*         printf("\n "); */
                   6397:     /*   } */
                   6398:     /* } */
                   6399:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6400:     /*   printf("\n gradg %d ",(int)age); */
                   6401:     /*   for(j=1; j<=nlstate;j++){ */
                   6402:     /*         printf("%d ",j); */
                   6403:     /*         for(theta=1; theta <=npar; theta++) */
                   6404:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6405:     /*         printf("\n "); */
                   6406:     /*   } */
                   6407:     /* } */
                   6408: 
                   6409:     for(i=1;i<=nlstate;i++)
                   6410:       varbpl[i][(int)age] =0.;
                   6411:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6412:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6413:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6414:     }else{
                   6415:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6416:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6417:     }
                   6418:     for(i=1;i<=nlstate;i++)
                   6419:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6420: 
                   6421:     fprintf(ficresvbl,"%.0f ",age );
                   6422:     if(nresult >=1)
                   6423:       fprintf(ficresvbl,"%d ",nres );
                   6424:     for(i=1; i<=nlstate;i++)
                   6425:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6426:     fprintf(ficresvbl,"\n");
                   6427:     free_vector(gp,1,nlstate);
                   6428:     free_vector(gm,1,nlstate);
                   6429:     free_matrix(mgm,1,npar,1,nlstate);
                   6430:     free_matrix(mgp,1,npar,1,nlstate);
                   6431:     free_matrix(gradg,1,npar,1,nlstate);
                   6432:     free_matrix(trgradg,1,nlstate,1,npar);
                   6433:   } /* End age */
                   6434: 
                   6435:   free_vector(xp,1,npar);
                   6436:   free_matrix(doldm,1,nlstate,1,npar);
                   6437:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6438: 
                   6439: }
                   6440: 
                   6441: /************ Variance of one-step probabilities  ******************/
                   6442: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6443:  {
                   6444:    int i, j=0,  k1, l1, tj;
                   6445:    int k2, l2, j1,  z1;
                   6446:    int k=0, l;
                   6447:    int first=1, first1, first2;
                   6448:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6449:    double **dnewm,**doldm;
                   6450:    double *xp;
                   6451:    double *gp, *gm;
                   6452:    double **gradg, **trgradg;
                   6453:    double **mu;
                   6454:    double age, cov[NCOVMAX+1];
                   6455:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6456:    int theta;
                   6457:    char fileresprob[FILENAMELENGTH];
                   6458:    char fileresprobcov[FILENAMELENGTH];
                   6459:    char fileresprobcor[FILENAMELENGTH];
                   6460:    double ***varpij;
                   6461: 
                   6462:    strcpy(fileresprob,"PROB_"); 
                   6463:    strcat(fileresprob,fileres);
                   6464:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6465:      printf("Problem with resultfile: %s\n", fileresprob);
                   6466:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6467:    }
                   6468:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6469:    strcat(fileresprobcov,fileresu);
                   6470:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6471:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6472:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6473:    }
                   6474:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6475:    strcat(fileresprobcor,fileresu);
                   6476:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6477:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6478:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6479:    }
                   6480:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6481:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6482:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6483:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6484:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6485:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6486:    pstamp(ficresprob);
                   6487:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6488:    fprintf(ficresprob,"# Age");
                   6489:    pstamp(ficresprobcov);
                   6490:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6491:    fprintf(ficresprobcov,"# Age");
                   6492:    pstamp(ficresprobcor);
                   6493:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6494:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6495: 
                   6496: 
1.222     brouard  6497:    for(i=1; i<=nlstate;i++)
                   6498:      for(j=1; j<=(nlstate+ndeath);j++){
                   6499:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6500:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6501:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6502:      }  
                   6503:    /* fprintf(ficresprob,"\n");
                   6504:       fprintf(ficresprobcov,"\n");
                   6505:       fprintf(ficresprobcor,"\n");
                   6506:    */
                   6507:    xp=vector(1,npar);
                   6508:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6509:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6510:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6511:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6512:    first=1;
                   6513:    fprintf(ficgp,"\n# Routine varprob");
                   6514:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6515:    fprintf(fichtm,"\n");
                   6516: 
1.288   ! brouard  6517:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6518:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6519:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6520: and drawn. It helps understanding how is the covariance between two incidences.\
                   6521:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6522:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6523: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6524: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6525: standard deviations wide on each axis. <br>\
                   6526:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6527:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6528: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6529: 
1.222     brouard  6530:    cov[1]=1;
                   6531:    /* tj=cptcoveff; */
1.225     brouard  6532:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6533:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6534:    j1=0;
1.224     brouard  6535:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6536:      if  (cptcovn>0) {
                   6537:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6538:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6539:        fprintf(ficresprob, "**********\n#\n");
                   6540:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6541:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6542:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6543:                        
1.222     brouard  6544:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6545:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6546:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6547:                        
                   6548:                        
1.222     brouard  6549:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6550:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6551:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6552:                        
1.222     brouard  6553:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6554:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6555:        fprintf(ficresprobcor, "**********\n#");    
                   6556:        if(invalidvarcomb[j1]){
                   6557:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6558:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6559:         continue;
                   6560:        }
                   6561:      }
                   6562:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6563:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6564:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6565:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6566:      for (age=bage; age<=fage; age ++){ 
                   6567:        cov[2]=age;
                   6568:        if(nagesqr==1)
                   6569:         cov[3]= age*age;
                   6570:        for (k=1; k<=cptcovn;k++) {
                   6571:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6572:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6573:                                                                    * 1  1 1 1 1
                   6574:                                                                    * 2  2 1 1 1
                   6575:                                                                    * 3  1 2 1 1
                   6576:                                                                    */
                   6577:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6578:        }
                   6579:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6580:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6581:        for (k=1; k<=cptcovprod;k++)
                   6582:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6583:                        
                   6584:                        
1.222     brouard  6585:        for(theta=1; theta <=npar; theta++){
                   6586:         for(i=1; i<=npar; i++)
                   6587:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6588:                                
1.222     brouard  6589:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6590:                                
1.222     brouard  6591:         k=0;
                   6592:         for(i=1; i<= (nlstate); i++){
                   6593:           for(j=1; j<=(nlstate+ndeath);j++){
                   6594:             k=k+1;
                   6595:             gp[k]=pmmij[i][j];
                   6596:           }
                   6597:         }
1.220     brouard  6598:                                
1.222     brouard  6599:         for(i=1; i<=npar; i++)
                   6600:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6601:                                
1.222     brouard  6602:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6603:         k=0;
                   6604:         for(i=1; i<=(nlstate); i++){
                   6605:           for(j=1; j<=(nlstate+ndeath);j++){
                   6606:             k=k+1;
                   6607:             gm[k]=pmmij[i][j];
                   6608:           }
                   6609:         }
1.220     brouard  6610:                                
1.222     brouard  6611:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6612:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6613:        }
1.126     brouard  6614: 
1.222     brouard  6615:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6616:         for(theta=1; theta <=npar; theta++)
                   6617:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6618:                        
1.222     brouard  6619:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6620:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6621:                        
1.222     brouard  6622:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6623:                        
1.222     brouard  6624:        k=0;
                   6625:        for(i=1; i<=(nlstate); i++){
                   6626:         for(j=1; j<=(nlstate+ndeath);j++){
                   6627:           k=k+1;
                   6628:           mu[k][(int) age]=pmmij[i][j];
                   6629:         }
                   6630:        }
                   6631:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6632:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6633:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6634:                        
1.222     brouard  6635:        /*printf("\n%d ",(int)age);
                   6636:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6637:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6638:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6639:         }*/
1.220     brouard  6640:                        
1.222     brouard  6641:        fprintf(ficresprob,"\n%d ",(int)age);
                   6642:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6643:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6644:                        
1.222     brouard  6645:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6646:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6647:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6648:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6649:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6650:        }
                   6651:        i=0;
                   6652:        for (k=1; k<=(nlstate);k++){
                   6653:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6654:           i++;
                   6655:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6656:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6657:           for (j=1; j<=i;j++){
                   6658:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6659:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6660:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6661:           }
                   6662:         }
                   6663:        }/* end of loop for state */
                   6664:      } /* end of loop for age */
                   6665:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6666:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6667:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6668:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6669:     
                   6670:      /* Confidence intervalle of pij  */
                   6671:      /*
                   6672:        fprintf(ficgp,"\nunset parametric;unset label");
                   6673:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6674:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6675:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6676:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6677:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6678:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6679:      */
                   6680:                
                   6681:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6682:      first1=1;first2=2;
                   6683:      for (k2=1; k2<=(nlstate);k2++){
                   6684:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6685:         if(l2==k2) continue;
                   6686:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6687:         for (k1=1; k1<=(nlstate);k1++){
                   6688:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6689:             if(l1==k1) continue;
                   6690:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6691:             if(i<=j) continue;
                   6692:             for (age=bage; age<=fage; age ++){ 
                   6693:               if ((int)age %5==0){
                   6694:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6695:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6696:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6697:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6698:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6699:                 c12=cv12/sqrt(v1*v2);
                   6700:                 /* Computing eigen value of matrix of covariance */
                   6701:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6702:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6703:                 if ((lc2 <0) || (lc1 <0) ){
                   6704:                   if(first2==1){
                   6705:                     first1=0;
                   6706:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6707:                   }
                   6708:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6709:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6710:                   /* lc2=fabs(lc2); */
                   6711:                 }
1.220     brouard  6712:                                                                
1.222     brouard  6713:                 /* Eigen vectors */
1.280     brouard  6714:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6715:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6716:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6717:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6718:                 }else
                   6719:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6720:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6721:                 v21=(lc1-v1)/cv12*v11;
                   6722:                 v12=-v21;
                   6723:                 v22=v11;
                   6724:                 tnalp=v21/v11;
                   6725:                 if(first1==1){
                   6726:                   first1=0;
                   6727:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6728:                 }
                   6729:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6730:                 /*printf(fignu*/
                   6731:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6732:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6733:                 if(first==1){
                   6734:                   first=0;
                   6735:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6736:                   fprintf(ficgp,"\nset parametric;unset label");
                   6737:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6738:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6739:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6740:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6741: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6742:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6743:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6744:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6745:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6746:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6747:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6748:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6749:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6750:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6751:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6752:                 }else{
                   6753:                   first=0;
                   6754:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6755:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6756:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6757:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6758:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6759:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6760:                 }/* if first */
                   6761:               } /* age mod 5 */
                   6762:             } /* end loop age */
                   6763:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6764:             first=1;
                   6765:           } /*l12 */
                   6766:         } /* k12 */
                   6767:        } /*l1 */
                   6768:      }/* k1 */
                   6769:    }  /* loop on combination of covariates j1 */
                   6770:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6771:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6772:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6773:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6774:    free_vector(xp,1,npar);
                   6775:    fclose(ficresprob);
                   6776:    fclose(ficresprobcov);
                   6777:    fclose(ficresprobcor);
                   6778:    fflush(ficgp);
                   6779:    fflush(fichtmcov);
                   6780:  }
1.126     brouard  6781: 
                   6782: 
                   6783: /******************* Printing html file ***********/
1.201     brouard  6784: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6785:                  int lastpass, int stepm, int weightopt, char model[],\
                   6786:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6787:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6788:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6789:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6790:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6791: 
                   6792:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6793:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6794: </ul>");
1.237     brouard  6795:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6796: </ul>", model);
1.214     brouard  6797:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6798:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6799:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6800:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6801:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6802:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6803:    fprintf(fichtm,"\
                   6804:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6805:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6806:    fprintf(fichtm,"\
1.217     brouard  6807:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6808:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6809:    fprintf(fichtm,"\
1.288   ! brouard  6810:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6811:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6812:    fprintf(fichtm,"\
1.288   ! brouard  6813:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6814:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6815:    fprintf(fichtm,"\
1.211     brouard  6816:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6817:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6818:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6819:    if(prevfcast==1){
                   6820:      fprintf(fichtm,"\
                   6821:  - Prevalence projections by age and states:                           \
1.201     brouard  6822:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6823:    }
1.126     brouard  6824: 
                   6825: 
1.225     brouard  6826:    m=pow(2,cptcoveff);
1.222     brouard  6827:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6828: 
1.264     brouard  6829:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6830: 
                   6831:    jj1=0;
                   6832: 
                   6833:    fprintf(fichtm," \n<ul>");
                   6834:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6835:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6836:      if(m != 1 && TKresult[nres]!= k1)
                   6837:        continue;
                   6838:      jj1++;
                   6839:      if (cptcovn > 0) {
                   6840:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6841:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6842:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6843:        }
                   6844:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6845:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6846:        }
                   6847:        fprintf(fichtm,"\">");
                   6848:        
                   6849:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6850:        fprintf(fichtm,"************ Results for covariates");
                   6851:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6852:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6853:        }
                   6854:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6855:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6856:        }
                   6857:        if(invalidvarcomb[k1]){
                   6858:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6859:         continue;
                   6860:        }
                   6861:        fprintf(fichtm,"</a></li>");
                   6862:      } /* cptcovn >0 */
                   6863:    }
                   6864:      fprintf(fichtm," \n</ul>");
                   6865: 
1.222     brouard  6866:    jj1=0;
1.237     brouard  6867: 
                   6868:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6869:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6870:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6871:        continue;
1.220     brouard  6872: 
1.222     brouard  6873:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6874:      jj1++;
                   6875:      if (cptcovn > 0) {
1.264     brouard  6876:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6877:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6878:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6879:        }
                   6880:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6881:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6882:        }
                   6883:        fprintf(fichtm,"\"</a>");
                   6884:  
1.222     brouard  6885:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6886:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6887:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6888:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6889:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6890:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6891:        }
1.237     brouard  6892:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6893:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6894:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6895:       }
                   6896:        
1.230     brouard  6897:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6898:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6899:        if(invalidvarcomb[k1]){
                   6900:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6901:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6902:         continue;
                   6903:        }
                   6904:      }
                   6905:      /* aij, bij */
1.259     brouard  6906:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6907: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6908:      /* Pij */
1.241     brouard  6909:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6910: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6911:      /* Quasi-incidences */
                   6912:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6913:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6914:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6915: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6916: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6917:      /* Survival functions (period) in state j */
                   6918:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6919:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6920: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6921:      }
                   6922:      /* State specific survival functions (period) */
                   6923:      for(cpt=1; cpt<=nlstate;cpt++){
                   6924:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6925:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.283     brouard  6926:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6927:      }
1.288   ! brouard  6928:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  6929:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6930:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6931: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6932:      }
                   6933:      if(backcast==1){
1.288   ! brouard  6934:        /* Backward prevalence in each health state */
1.222     brouard  6935:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6936:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6937: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6938:        }
1.217     brouard  6939:      }
1.222     brouard  6940:      if(prevfcast==1){
1.288   ! brouard  6941:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  6942:        for(cpt=1; cpt<=nlstate;cpt++){
1.288   ! brouard  6943:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.273     brouard  6944: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6945:        }
                   6946:      }
1.268     brouard  6947:      if(backcast==1){
                   6948:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6949:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6950:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6951:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6952:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6953: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6954:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6955:        }
                   6956:      }
1.220     brouard  6957:         
1.222     brouard  6958:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6959:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6960: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6961:      }
                   6962:      /* } /\* end i1 *\/ */
                   6963:    }/* End k1 */
                   6964:    fprintf(fichtm,"</ul>");
1.126     brouard  6965: 
1.222     brouard  6966:    fprintf(fichtm,"\
1.126     brouard  6967: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6968:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6969:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6970: But because parameters are usually highly correlated (a higher incidence of disability \
                   6971: and a higher incidence of recovery can give very close observed transition) it might \
                   6972: be very useful to look not only at linear confidence intervals estimated from the \
                   6973: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6974: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6975: covariance matrix of the one-step probabilities. \
                   6976: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6977: 
1.222     brouard  6978:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6979:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6980:    fprintf(fichtm,"\
1.126     brouard  6981:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6982:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6983: 
1.222     brouard  6984:    fprintf(fichtm,"\
1.126     brouard  6985:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6986:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6987:    fprintf(fichtm,"\
1.126     brouard  6988:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6989:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6990:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6991:    fprintf(fichtm,"\
1.126     brouard  6992:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6993:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6994:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6995:    fprintf(fichtm,"\
1.288   ! brouard  6996:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  6997:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   6998:    fprintf(fichtm,"\
1.128     brouard  6999:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7000:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7001:    fprintf(fichtm,"\
1.288   ! brouard  7002:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7003:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7004: 
                   7005: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7006: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7007: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7008: /*     <br>",fileres,fileres,fileres,fileres); */
                   7009: /*  else  */
                   7010: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7011:    fflush(fichtm);
                   7012:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7013: 
1.225     brouard  7014:    m=pow(2,cptcoveff);
1.222     brouard  7015:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7016: 
1.222     brouard  7017:    jj1=0;
1.237     brouard  7018: 
1.241     brouard  7019:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7020:    for(k1=1; k1<=m;k1++){
1.253     brouard  7021:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7022:        continue;
1.222     brouard  7023:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7024:      jj1++;
1.126     brouard  7025:      if (cptcovn > 0) {
                   7026:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7027:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7028:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7029:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7030:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7031:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7032:       }
                   7033: 
1.126     brouard  7034:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7035: 
1.222     brouard  7036:        if(invalidvarcomb[k1]){
                   7037:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7038:         continue;
                   7039:        }
1.126     brouard  7040:      }
                   7041:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7042:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7043: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7044: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7045:      }
                   7046:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7047: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7048: true period expectancies (those weighted with period prevalences are also\
                   7049:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7050:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7051: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7052:      /* } /\* end i1 *\/ */
                   7053:    }/* End k1 */
1.241     brouard  7054:   }/* End nres */
1.222     brouard  7055:    fprintf(fichtm,"</ul>");
                   7056:    fflush(fichtm);
1.126     brouard  7057: }
                   7058: 
                   7059: /******************* Gnuplot file **************/
1.270     brouard  7060: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7061: 
                   7062:   char dirfileres[132],optfileres[132];
1.264     brouard  7063:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7064:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7065:   int lv=0, vlv=0, kl=0;
1.130     brouard  7066:   int ng=0;
1.201     brouard  7067:   int vpopbased;
1.223     brouard  7068:   int ioffset; /* variable offset for columns */
1.270     brouard  7069:   int iyearc=1; /* variable column for year of projection  */
                   7070:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7071:   int nres=0; /* Index of resultline */
1.266     brouard  7072:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7073: 
1.126     brouard  7074: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7075: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7076: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7077: /*   } */
                   7078: 
                   7079:   /*#ifdef windows */
                   7080:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7081:   /*#endif */
1.225     brouard  7082:   m=pow(2,cptcoveff);
1.126     brouard  7083: 
1.274     brouard  7084:   /* diagram of the model */
                   7085:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7086:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7087:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7088:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7089: 
                   7090:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7091:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7092:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7093:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7094:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7095:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7096:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7097: 
1.202     brouard  7098:   /* Contribution to likelihood */
                   7099:   /* Plot the probability implied in the likelihood */
1.223     brouard  7100:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7101:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7102:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7103:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7104: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7105:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7106: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7107:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7108:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7109:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7110:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7111:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7112:   for (i=1; i<= nlstate ; i ++) {
                   7113:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7114:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7115:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7116:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7117:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7118:     }
                   7119:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7120:   }
                   7121:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7122:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7123:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7124:   fprintf(ficgp,"\nset out;unset log\n");
                   7125:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7126: 
1.126     brouard  7127:   strcpy(dirfileres,optionfilefiname);
                   7128:   strcpy(optfileres,"vpl");
1.223     brouard  7129:   /* 1eme*/
1.238     brouard  7130:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7131:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7132:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7133:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7134:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7135:          continue;
                   7136:        /* We are interested in selected combination by the resultline */
1.246     brouard  7137:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288   ! brouard  7138:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7139:        strcpy(gplotlabel,"(");
1.238     brouard  7140:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7141:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7142:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7143:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7144:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7145:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7146:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7147:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7148:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7149:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7150:        }
                   7151:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7152:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7153:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7154:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7155:        }
                   7156:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7157:        /* printf("\n#\n"); */
1.238     brouard  7158:        fprintf(ficgp,"\n#\n");
                   7159:        if(invalidvarcomb[k1]){
1.260     brouard  7160:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7161:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7162:          continue;
                   7163:        }
1.235     brouard  7164:       
1.241     brouard  7165:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7166:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7167:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7168:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7169:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7170:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7171:       /* k1-1 error should be nres-1*/
1.238     brouard  7172:        for (i=1; i<= nlstate ; i ++) {
                   7173:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7174:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7175:        }
1.288   ! brouard  7176:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7177:        for (i=1; i<= nlstate ; i ++) {
                   7178:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7179:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7180:        } 
1.260     brouard  7181:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7182:        for (i=1; i<= nlstate ; i ++) {
                   7183:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7184:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7185:        }  
1.265     brouard  7186:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7187:        
                   7188:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7189:         if(cptcoveff ==0){
1.271     brouard  7190:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7191:        }else{
                   7192:          kl=0;
                   7193:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7194:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7195:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7196:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7197:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7198:            vlv= nbcode[Tvaraff[k]][lv];
                   7199:            kl++;
                   7200:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7201:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7202:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7203:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7204:            if(k==cptcoveff){
                   7205:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7206:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7207:            }else{
                   7208:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7209:              kl++;
                   7210:            }
                   7211:          } /* end covariate */
                   7212:        } /* end if no covariate */
                   7213: 
1.238     brouard  7214:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7215:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7216:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7217:          if(cptcoveff ==0){
1.245     brouard  7218:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7219:          }else{
                   7220:            kl=0;
                   7221:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7222:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7223:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7224:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7225:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7226:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7227:              kl++;
1.238     brouard  7228:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7229:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7230:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7231:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7232:              if(k==cptcoveff){
1.245     brouard  7233:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7234:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7235:              }else{
                   7236:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7237:                kl++;
                   7238:              }
                   7239:            } /* end covariate */
                   7240:          } /* end if no covariate */
1.268     brouard  7241:          if(backcast == 1){
                   7242:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7243:            /* k1-1 error should be nres-1*/
                   7244:            for (i=1; i<= nlstate ; i ++) {
                   7245:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7246:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7247:            }
1.271     brouard  7248:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7249:            for (i=1; i<= nlstate ; i ++) {
                   7250:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7251:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7252:            } 
1.276     brouard  7253:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7254:            for (i=1; i<= nlstate ; i ++) {
                   7255:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7256:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7257:            } 
1.274     brouard  7258:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7259:          } /* end if backprojcast */
1.238     brouard  7260:        } /* end if backcast */
1.276     brouard  7261:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7262:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7263:       } /* nres */
1.201     brouard  7264:     } /* k1 */
                   7265:   } /* cpt */
1.235     brouard  7266: 
                   7267:   
1.126     brouard  7268:   /*2 eme*/
1.238     brouard  7269:   for (k1=1; k1<= m ; k1 ++){  
                   7270:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7271:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7272:        continue;
                   7273:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7274:       strcpy(gplotlabel,"(");
1.238     brouard  7275:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7276:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7277:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7278:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7279:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7280:        vlv= nbcode[Tvaraff[k]][lv];
                   7281:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7282:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7283:       }
1.237     brouard  7284:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7285:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7286:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7287:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7288:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7289:       }
1.264     brouard  7290:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7291:       fprintf(ficgp,"\n#\n");
1.223     brouard  7292:       if(invalidvarcomb[k1]){
                   7293:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7294:        continue;
                   7295:       }
1.219     brouard  7296:                        
1.241     brouard  7297:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7298:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7299:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7300:        if(vpopbased==0){
1.238     brouard  7301:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7302:        }else
1.238     brouard  7303:          fprintf(ficgp,"\nreplot ");
                   7304:        for (i=1; i<= nlstate+1 ; i ++) {
                   7305:          k=2*i;
1.261     brouard  7306:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7307:          for (j=1; j<= nlstate+1 ; j ++) {
                   7308:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7309:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7310:          }   
                   7311:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7312:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7313:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7314:          for (j=1; j<= nlstate+1 ; j ++) {
                   7315:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7316:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7317:          }   
                   7318:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7319:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7320:          for (j=1; j<= nlstate+1 ; j ++) {
                   7321:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7322:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7323:          }   
                   7324:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7325:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7326:        } /* state */
                   7327:       } /* vpopbased */
1.264     brouard  7328:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7329:     } /* end nres */
                   7330:   } /* k1 end 2 eme*/
                   7331:        
                   7332:        
                   7333:   /*3eme*/
                   7334:   for (k1=1; k1<= m ; k1 ++){
                   7335:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7336:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7337:        continue;
                   7338: 
                   7339:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7340:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7341:        strcpy(gplotlabel,"(");
1.238     brouard  7342:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7343:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7344:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7345:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7346:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7347:          vlv= nbcode[Tvaraff[k]][lv];
                   7348:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7349:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7350:        }
                   7351:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7352:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7353:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7354:        }       
1.264     brouard  7355:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7356:        fprintf(ficgp,"\n#\n");
                   7357:        if(invalidvarcomb[k1]){
                   7358:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7359:          continue;
                   7360:        }
                   7361:                        
                   7362:        /*       k=2+nlstate*(2*cpt-2); */
                   7363:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7364:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7365:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7366:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7367: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7368:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7369:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7370:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7371:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7372:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7373:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7374:                                
1.238     brouard  7375:        */
                   7376:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7377:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7378:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7379:                                
1.238     brouard  7380:        } 
1.261     brouard  7381:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7382:       }
1.264     brouard  7383:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7384:     } /* end nres */
                   7385:   } /* end kl 3eme */
1.126     brouard  7386:   
1.223     brouard  7387:   /* 4eme */
1.201     brouard  7388:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7389:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7390:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7391:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7392:        continue;
1.238     brouard  7393:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7394:        strcpy(gplotlabel,"(");
1.238     brouard  7395:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7396:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7397:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7398:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7399:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7400:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7401:          vlv= nbcode[Tvaraff[k]][lv];
                   7402:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7403:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7404:        }
                   7405:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7406:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7407:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7408:        }       
1.264     brouard  7409:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7410:        fprintf(ficgp,"\n#\n");
                   7411:        if(invalidvarcomb[k1]){
                   7412:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7413:          continue;
1.223     brouard  7414:        }
1.238     brouard  7415:       
1.241     brouard  7416:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7417:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7418:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7419: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7420:        k=3;
                   7421:        for (i=1; i<= nlstate ; i ++){
                   7422:          if(i==1){
                   7423:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7424:          }else{
                   7425:            fprintf(ficgp,", '' ");
                   7426:          }
                   7427:          l=(nlstate+ndeath)*(i-1)+1;
                   7428:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7429:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7430:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7431:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7432:        } /* nlstate */
1.264     brouard  7433:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7434:       } /* end cpt state*/ 
                   7435:     } /* end nres */
                   7436:   } /* end covariate k1 */  
                   7437: 
1.220     brouard  7438: /* 5eme */
1.201     brouard  7439:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7440:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7441:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7442:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7443:        continue;
1.238     brouard  7444:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7445:        strcpy(gplotlabel,"(");
1.238     brouard  7446:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7447:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7448:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7449:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7450:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7451:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7452:          vlv= nbcode[Tvaraff[k]][lv];
                   7453:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7454:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7455:        }
                   7456:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7457:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7458:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7459:        }       
1.264     brouard  7460:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7461:        fprintf(ficgp,"\n#\n");
                   7462:        if(invalidvarcomb[k1]){
                   7463:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7464:          continue;
                   7465:        }
1.227     brouard  7466:       
1.241     brouard  7467:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7468:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7469:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7470: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7471:        k=3;
                   7472:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7473:          if(j==1)
                   7474:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7475:          else
                   7476:            fprintf(ficgp,", '' ");
                   7477:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7478:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7479:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7480:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7481:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7482:        } /* nlstate */
                   7483:        fprintf(ficgp,", '' ");
                   7484:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7485:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7486:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7487:          if(j < nlstate)
                   7488:            fprintf(ficgp,"$%d +",k+l);
                   7489:          else
                   7490:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7491:        }
1.264     brouard  7492:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7493:       } /* end cpt state*/ 
                   7494:     } /* end covariate */  
                   7495:   } /* end nres */
1.227     brouard  7496:   
1.220     brouard  7497: /* 6eme */
1.202     brouard  7498:   /* CV preval stable (period) for each covariate */
1.237     brouard  7499:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7500:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7501:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7502:       continue;
1.255     brouard  7503:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7504:       strcpy(gplotlabel,"(");      
1.288   ! brouard  7505:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7506:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7507:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7508:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7509:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7510:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7511:        vlv= nbcode[Tvaraff[k]][lv];
                   7512:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7513:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7514:       }
1.237     brouard  7515:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7516:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7517:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7518:       }        
1.264     brouard  7519:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7520:       fprintf(ficgp,"\n#\n");
1.223     brouard  7521:       if(invalidvarcomb[k1]){
1.227     brouard  7522:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7523:        continue;
1.223     brouard  7524:       }
1.227     brouard  7525:       
1.241     brouard  7526:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7527:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7528:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7529: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7530:       k=3; /* Offset */
1.255     brouard  7531:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7532:        if(i==1)
                   7533:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7534:        else
                   7535:          fprintf(ficgp,", '' ");
1.255     brouard  7536:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7537:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7538:        for (j=2; j<= nlstate ; j ++)
                   7539:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7540:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7541:       } /* nlstate */
1.264     brouard  7542:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7543:     } /* end cpt state*/ 
                   7544:   } /* end covariate */  
1.227     brouard  7545:   
                   7546:   
1.220     brouard  7547: /* 7eme */
1.218     brouard  7548:   if(backcast == 1){
1.288   ! brouard  7549:     /* CV backward prevalence  for each covariate */
1.237     brouard  7550:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7551:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7552:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7553:        continue;
1.268     brouard  7554:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7555:        strcpy(gplotlabel,"(");      
1.288   ! brouard  7556:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7557:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7558:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7559:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7560:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7561:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7562:          vlv= nbcode[Tvaraff[k]][lv];
                   7563:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7564:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7565:        }
1.237     brouard  7566:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7567:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7568:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7569:        }       
1.264     brouard  7570:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7571:        fprintf(ficgp,"\n#\n");
                   7572:        if(invalidvarcomb[k1]){
                   7573:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7574:          continue;
                   7575:        }
                   7576:        
1.241     brouard  7577:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7578:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7579:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7580: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7581:        k=3; /* Offset */
1.268     brouard  7582:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7583:          if(i==1)
                   7584:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7585:          else
                   7586:            fprintf(ficgp,", '' ");
                   7587:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7588:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7589:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7590:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7591:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7592:          /* for (j=2; j<= nlstate ; j ++) */
                   7593:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7594:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7595:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7596:        } /* nlstate */
1.264     brouard  7597:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7598:       } /* end cpt state*/ 
                   7599:     } /* end covariate */  
                   7600:   } /* End if backcast */
                   7601:   
1.223     brouard  7602:   /* 8eme */
1.218     brouard  7603:   if(prevfcast==1){
1.288   ! brouard  7604:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7605:     
1.237     brouard  7606:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7607:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7608:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7609:        continue;
1.211     brouard  7610:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7611:        strcpy(gplotlabel,"(");      
1.288   ! brouard  7612:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7613:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7614:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7615:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7616:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7617:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7618:          vlv= nbcode[Tvaraff[k]][lv];
                   7619:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7620:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7621:        }
1.237     brouard  7622:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7623:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7624:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7625:        }       
1.264     brouard  7626:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7627:        fprintf(ficgp,"\n#\n");
                   7628:        if(invalidvarcomb[k1]){
                   7629:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7630:          continue;
                   7631:        }
                   7632:        
                   7633:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7634:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7635:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7636:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7637: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7638: 
                   7639:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7640:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7641:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7642:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7643:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7644:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7645:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7646:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7647:          if(i==istart){
1.227     brouard  7648:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7649:          }else{
                   7650:            fprintf(ficgp,",\\\n '' ");
                   7651:          }
                   7652:          if(cptcoveff ==0){ /* No covariate */
                   7653:            ioffset=2; /* Age is in 2 */
                   7654:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7655:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7656:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7657:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7658:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7659:            if(i==nlstate+1){
1.270     brouard  7660:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7661:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7662:              fprintf(ficgp,",\\\n '' ");
                   7663:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7664:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7665:                     offyear,                           \
1.268     brouard  7666:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7667:            }else
1.227     brouard  7668:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7669:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7670:          }else{ /* more than 2 covariates */
1.270     brouard  7671:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7672:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7673:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7674:            iyearc=ioffset-1;
                   7675:            iagec=ioffset;
1.227     brouard  7676:            fprintf(ficgp," u %d:(",ioffset); 
                   7677:            kl=0;
                   7678:            strcpy(gplotcondition,"(");
                   7679:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7680:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7681:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7682:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7683:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7684:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7685:              kl++;
                   7686:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7687:              kl++;
                   7688:              if(k <cptcoveff && cptcoveff>1)
                   7689:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7690:            }
                   7691:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7692:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7693:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7694:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7695:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7696:            if(i==nlstate+1){
1.270     brouard  7697:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7698:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7699:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7700:              fprintf(ficgp," u %d:(",iagec); 
                   7701:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7702:                      iyearc, iagec, offyear,                           \
                   7703:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7704: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7705:            }else{
                   7706:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7707:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7708:            }
                   7709:          } /* end if covariate */
                   7710:        } /* nlstate */
1.264     brouard  7711:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7712:       } /* end cpt state*/
                   7713:     } /* end covariate */
                   7714:   } /* End if prevfcast */
1.227     brouard  7715:   
1.268     brouard  7716:   if(backcast==1){
                   7717:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7718:     
                   7719:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7720:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7721:       if(m != 1 && TKresult[nres]!= k1)
                   7722:        continue;
                   7723:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7724:        strcpy(gplotlabel,"(");      
                   7725:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7726:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7727:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7728:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7729:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7730:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7731:          vlv= nbcode[Tvaraff[k]][lv];
                   7732:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7733:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7734:        }
                   7735:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7736:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7737:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7738:        }       
                   7739:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7740:        fprintf(ficgp,"\n#\n");
                   7741:        if(invalidvarcomb[k1]){
                   7742:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7743:          continue;
                   7744:        }
                   7745:        
                   7746:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7747:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7748:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7749:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7750: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7751: 
                   7752:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7753:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7754:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7755:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7756:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7757:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7758:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7759:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7760:          if(i==istart){
                   7761:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7762:          }else{
                   7763:            fprintf(ficgp,",\\\n '' ");
                   7764:          }
                   7765:          if(cptcoveff ==0){ /* No covariate */
                   7766:            ioffset=2; /* Age is in 2 */
                   7767:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7768:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7769:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7770:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7771:            fprintf(ficgp," u %d:(", ioffset); 
                   7772:            if(i==nlstate+1){
1.270     brouard  7773:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7774:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7775:              fprintf(ficgp,",\\\n '' ");
                   7776:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7777:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7778:                     offbyear,                          \
                   7779:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7780:            }else
                   7781:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7782:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7783:          }else{ /* more than 2 covariates */
1.270     brouard  7784:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7785:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7786:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7787:            iyearc=ioffset-1;
                   7788:            iagec=ioffset;
1.268     brouard  7789:            fprintf(ficgp," u %d:(",ioffset); 
                   7790:            kl=0;
                   7791:            strcpy(gplotcondition,"(");
                   7792:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7793:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7794:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7795:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7796:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7797:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7798:              kl++;
                   7799:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7800:              kl++;
                   7801:              if(k <cptcoveff && cptcoveff>1)
                   7802:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7803:            }
                   7804:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7805:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7806:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7807:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7808:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7809:            if(i==nlstate+1){
1.270     brouard  7810:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7811:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7812:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7813:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7814:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7815:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7816:                      iyearc,iagec,offbyear,                            \
                   7817:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7818: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7819:            }else{
                   7820:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7821:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7822:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7823:            }
                   7824:          } /* end if covariate */
                   7825:        } /* nlstate */
                   7826:        fprintf(ficgp,"\nset out; unset label;\n");
                   7827:       } /* end cpt state*/
                   7828:     } /* end covariate */
                   7829:   } /* End if backcast */
                   7830:   
1.227     brouard  7831:   
1.238     brouard  7832:   /* 9eme writing MLE parameters */
                   7833:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7834:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7835:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7836:     for(k=1; k <=(nlstate+ndeath); k++){
                   7837:       if (k != i) {
1.227     brouard  7838:        fprintf(ficgp,"#   current state %d\n",k);
                   7839:        for(j=1; j <=ncovmodel; j++){
                   7840:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7841:          jk++; 
                   7842:        }
                   7843:        fprintf(ficgp,"\n");
1.126     brouard  7844:       }
                   7845:     }
1.223     brouard  7846:   }
1.187     brouard  7847:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7848:   
1.145     brouard  7849:   /*goto avoid;*/
1.238     brouard  7850:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7851:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7852:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7853:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7854:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7855:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7856:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7857:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7858:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7859:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7860:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7861:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7862:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7863:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7864:   fprintf(ficgp,"#\n");
1.223     brouard  7865:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7866:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7867:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7868:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7869:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7870:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7871:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7872:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7873:        continue;
1.264     brouard  7874:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7875:       strcpy(gplotlabel,"(");
1.276     brouard  7876:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7877:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7878:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7879:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7880:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7881:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7882:        vlv= nbcode[Tvaraff[k]][lv];
                   7883:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7884:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7885:       }
1.237     brouard  7886:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7887:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7888:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7889:       }        
1.264     brouard  7890:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7891:       fprintf(ficgp,"\n#\n");
1.264     brouard  7892:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7893:       fprintf(ficgp,"\nset key outside ");
                   7894:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7895:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7896:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7897:       if (ng==1){
                   7898:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7899:        fprintf(ficgp,"\nunset log y");
                   7900:       }else if (ng==2){
                   7901:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7902:        fprintf(ficgp,"\nset log y");
                   7903:       }else if (ng==3){
                   7904:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7905:        fprintf(ficgp,"\nset log y");
                   7906:       }else
                   7907:        fprintf(ficgp,"\nunset title ");
                   7908:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7909:       i=1;
                   7910:       for(k2=1; k2<=nlstate; k2++) {
                   7911:        k3=i;
                   7912:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7913:          if (k != k2){
                   7914:            switch( ng) {
                   7915:            case 1:
                   7916:              if(nagesqr==0)
                   7917:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7918:              else /* nagesqr =1 */
                   7919:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7920:              break;
                   7921:            case 2: /* ng=2 */
                   7922:              if(nagesqr==0)
                   7923:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7924:              else /* nagesqr =1 */
                   7925:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7926:              break;
                   7927:            case 3:
                   7928:              if(nagesqr==0)
                   7929:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7930:              else /* nagesqr =1 */
                   7931:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7932:              break;
                   7933:            }
                   7934:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7935:            ijp=1; /* product no age */
                   7936:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7937:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7938:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7939:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7940:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7941:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7942:                    if(DummyV[j]==0){
                   7943:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7944:                    }else{ /* quantitative */
                   7945:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7946:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7947:                    }
                   7948:                    ij++;
1.237     brouard  7949:                  }
1.268     brouard  7950:                } 
                   7951:              }else if(cptcovprod >0){
                   7952:                if(j==Tprod[ijp]) { /* */ 
                   7953:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7954:                  if(ijp <=cptcovprod) { /* Product */
                   7955:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7956:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7957:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7958:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7959:                      }else{ /* Vn is dummy and Vm is quanti */
                   7960:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7961:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7962:                      }
                   7963:                    }else{ /* Vn*Vm Vn is quanti */
                   7964:                      if(DummyV[Tvard[ijp][2]]==0){
                   7965:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7966:                      }else{ /* Both quanti */
                   7967:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7968:                      }
1.237     brouard  7969:                    }
1.268     brouard  7970:                    ijp++;
1.237     brouard  7971:                  }
1.268     brouard  7972:                } /* end Tprod */
1.237     brouard  7973:              } else{  /* simple covariate */
1.264     brouard  7974:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7975:                if(Dummy[j]==0){
                   7976:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7977:                }else{ /* quantitative */
                   7978:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7979:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7980:                }
1.237     brouard  7981:              } /* end simple */
                   7982:            } /* end j */
1.223     brouard  7983:          }else{
                   7984:            i=i-ncovmodel;
                   7985:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7986:              fprintf(ficgp," (1.");
                   7987:          }
1.227     brouard  7988:          
1.223     brouard  7989:          if(ng != 1){
                   7990:            fprintf(ficgp,")/(1");
1.227     brouard  7991:            
1.264     brouard  7992:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7993:              if(nagesqr==0)
1.264     brouard  7994:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7995:              else /* nagesqr =1 */
1.264     brouard  7996:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  7997:               
1.223     brouard  7998:              ij=1;
                   7999:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8000:                 if(cptcovage >0){ 
                   8001:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8002:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8003:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8004:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8005:                       ij++;
                   8006:                     }
                   8007:                   }
                   8008:                 }else
                   8009:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8010:              }
                   8011:              fprintf(ficgp,")");
                   8012:            }
                   8013:            fprintf(ficgp,")");
                   8014:            if(ng ==2)
1.276     brouard  8015:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8016:            else /* ng= 3 */
1.276     brouard  8017:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8018:          }else{ /* end ng <> 1 */
                   8019:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8020:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8021:          }
                   8022:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8023:            fprintf(ficgp,",");
                   8024:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8025:            fprintf(ficgp,",");
                   8026:          i=i+ncovmodel;
                   8027:        } /* end k */
                   8028:       } /* end k2 */
1.276     brouard  8029:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8030:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8031:     } /* end k1 */
1.223     brouard  8032:   } /* end ng */
                   8033:   /* avoid: */
                   8034:   fflush(ficgp); 
1.126     brouard  8035: }  /* end gnuplot */
                   8036: 
                   8037: 
                   8038: /*************** Moving average **************/
1.219     brouard  8039: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8040:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8041:    
1.222     brouard  8042:    int i, cpt, cptcod;
                   8043:    int modcovmax =1;
                   8044:    int mobilavrange, mob;
                   8045:    int iage=0;
1.288   ! brouard  8046:    int firstA1=0, firstA2=0;
1.222     brouard  8047: 
1.266     brouard  8048:    double sum=0., sumr=0.;
1.222     brouard  8049:    double age;
1.266     brouard  8050:    double *sumnewp, *sumnewm, *sumnewmr;
                   8051:    double *agemingood, *agemaxgood; 
                   8052:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8053:   
                   8054:   
1.278     brouard  8055:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8056:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8057: 
                   8058:    sumnewp = vector(1,ncovcombmax);
                   8059:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8060:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8061:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8062:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8063:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8064:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8065: 
                   8066:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8067:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8068:      sumnewp[cptcod]=0.;
1.266     brouard  8069:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8070:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8071:    }
                   8072:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8073:   
1.266     brouard  8074:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8075:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8076:      else mobilavrange=mobilav;
                   8077:      for (age=bage; age<=fage; age++)
                   8078:        for (i=1; i<=nlstate;i++)
                   8079:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8080:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8081:      /* We keep the original values on the extreme ages bage, fage and for 
                   8082:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8083:        we use a 5 terms etc. until the borders are no more concerned. 
                   8084:      */ 
                   8085:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8086:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8087:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8088:           sumnewm[cptcod]=0.;
                   8089:           for (i=1; i<=nlstate;i++){
1.222     brouard  8090:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8091:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8092:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8093:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8094:             }
                   8095:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8096:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8097:           } /* end i */
                   8098:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8099:         } /* end cptcod */
1.222     brouard  8100:        }/* end age */
                   8101:      }/* end mob */
1.266     brouard  8102:    }else{
                   8103:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8104:      return -1;
1.266     brouard  8105:    }
                   8106: 
                   8107:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8108:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8109:      if(invalidvarcomb[cptcod]){
                   8110:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8111:        continue;
                   8112:      }
1.219     brouard  8113: 
1.266     brouard  8114:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8115:        sumnewm[cptcod]=0.;
                   8116:        sumnewmr[cptcod]=0.;
                   8117:        for (i=1; i<=nlstate;i++){
                   8118:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8119:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8120:        }
                   8121:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8122:         agemingoodr[cptcod]=age;
                   8123:        }
                   8124:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8125:           agemingood[cptcod]=age;
                   8126:        }
                   8127:      } /* age */
                   8128:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8129:        sumnewm[cptcod]=0.;
1.266     brouard  8130:        sumnewmr[cptcod]=0.;
1.222     brouard  8131:        for (i=1; i<=nlstate;i++){
                   8132:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8133:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8134:        }
                   8135:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8136:         agemaxgoodr[cptcod]=age;
1.222     brouard  8137:        }
                   8138:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8139:         agemaxgood[cptcod]=age;
                   8140:        }
                   8141:      } /* age */
                   8142:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8143:      /* but they will change */
1.288   ! brouard  8144:      firstA1=0;firstA2=0;
1.266     brouard  8145:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8146:        sumnewm[cptcod]=0.;
                   8147:        sumnewmr[cptcod]=0.;
                   8148:        for (i=1; i<=nlstate;i++){
                   8149:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8150:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8151:        }
                   8152:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8153:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8154:           agemaxgoodr[cptcod]=age;  /* age min */
                   8155:           for (i=1; i<=nlstate;i++)
                   8156:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8157:         }else{ /* bad we change the value with the values of good ages */
                   8158:           for (i=1; i<=nlstate;i++){
                   8159:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8160:           } /* i */
                   8161:         } /* end bad */
                   8162:        }else{
                   8163:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8164:           agemaxgood[cptcod]=age;
                   8165:         }else{ /* bad we change the value with the values of good ages */
                   8166:           for (i=1; i<=nlstate;i++){
                   8167:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8168:           } /* i */
                   8169:         } /* end bad */
                   8170:        }/* end else */
                   8171:        sum=0.;sumr=0.;
                   8172:        for (i=1; i<=nlstate;i++){
                   8173:         sum+=mobaverage[(int)age][i][cptcod];
                   8174:         sumr+=probs[(int)age][i][cptcod];
                   8175:        }
                   8176:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288   ! brouard  8177:         if(!firstA1){
        !          8178:           firstA1=1;
        !          8179:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
        !          8180:         }
        !          8181:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8182:        } /* end bad */
                   8183:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8184:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288   ! brouard  8185:         if(!firstA2){
        !          8186:           firstA2=1;
        !          8187:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
        !          8188:         }
        !          8189:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8190:        } /* end bad */
                   8191:      }/* age */
1.266     brouard  8192: 
                   8193:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8194:        sumnewm[cptcod]=0.;
1.266     brouard  8195:        sumnewmr[cptcod]=0.;
1.222     brouard  8196:        for (i=1; i<=nlstate;i++){
                   8197:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8198:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8199:        } 
                   8200:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8201:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8202:           agemingoodr[cptcod]=age;
                   8203:           for (i=1; i<=nlstate;i++)
                   8204:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8205:         }else{ /* bad we change the value with the values of good ages */
                   8206:           for (i=1; i<=nlstate;i++){
                   8207:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8208:           } /* i */
                   8209:         } /* end bad */
                   8210:        }else{
                   8211:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8212:           agemingood[cptcod]=age;
                   8213:         }else{ /* bad */
                   8214:           for (i=1; i<=nlstate;i++){
                   8215:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8216:           } /* i */
                   8217:         } /* end bad */
                   8218:        }/* end else */
                   8219:        sum=0.;sumr=0.;
                   8220:        for (i=1; i<=nlstate;i++){
                   8221:         sum+=mobaverage[(int)age][i][cptcod];
                   8222:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8223:        }
1.266     brouard  8224:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8225:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8226:        } /* end bad */
                   8227:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8228:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8229:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8230:        } /* end bad */
                   8231:      }/* age */
1.266     brouard  8232: 
1.222     brouard  8233:                
                   8234:      for (age=bage; age<=fage; age++){
1.235     brouard  8235:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8236:        sumnewp[cptcod]=0.;
                   8237:        sumnewm[cptcod]=0.;
                   8238:        for (i=1; i<=nlstate;i++){
                   8239:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8240:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8241:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8242:        }
                   8243:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8244:      }
                   8245:      /* printf("\n"); */
                   8246:      /* } */
1.266     brouard  8247: 
1.222     brouard  8248:      /* brutal averaging */
1.266     brouard  8249:      /* for (i=1; i<=nlstate;i++){ */
                   8250:      /*   for (age=1; age<=bage; age++){ */
                   8251:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8252:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8253:      /*   }     */
                   8254:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8255:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8256:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8257:      /*   } */
                   8258:      /* } /\* end i status *\/ */
                   8259:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8260:      /*   for (age=1; age<=AGESUP; age++){ */
                   8261:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8262:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8263:      /*   } */
                   8264:      /* } */
1.222     brouard  8265:    }/* end cptcod */
1.266     brouard  8266:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8267:    free_vector(agemaxgood,1, ncovcombmax);
                   8268:    free_vector(agemingood,1, ncovcombmax);
                   8269:    free_vector(agemingoodr,1, ncovcombmax);
                   8270:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8271:    free_vector(sumnewm,1, ncovcombmax);
                   8272:    free_vector(sumnewp,1, ncovcombmax);
                   8273:    return 0;
                   8274:  }/* End movingaverage */
1.218     brouard  8275:  
1.126     brouard  8276: 
                   8277: /************** Forecasting ******************/
1.269     brouard  8278:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8279:   /* proj1, year, month, day of starting projection 
                   8280:      agemin, agemax range of age
                   8281:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8282:      anproj2 year of en of projection (same day and month as proj1).
                   8283:   */
1.267     brouard  8284:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8285:   double agec; /* generic age */
                   8286:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8287:   double *popeffectif,*popcount;
                   8288:   double ***p3mat;
1.218     brouard  8289:   /* double ***mobaverage; */
1.126     brouard  8290:   char fileresf[FILENAMELENGTH];
                   8291: 
                   8292:   agelim=AGESUP;
1.211     brouard  8293:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8294:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8295:      We still use firstpass and lastpass as another selection.
                   8296:   */
1.214     brouard  8297:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8298:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8299:  
1.201     brouard  8300:   strcpy(fileresf,"F_"); 
                   8301:   strcat(fileresf,fileresu);
1.126     brouard  8302:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8303:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8304:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8305:   }
1.235     brouard  8306:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8307:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8308: 
1.225     brouard  8309:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8310: 
                   8311: 
                   8312:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8313:   if (stepm<=12) stepsize=1;
                   8314:   if(estepm < stepm){
                   8315:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8316:   }
1.270     brouard  8317:   else{
                   8318:     hstepm=estepm;   
                   8319:   }
                   8320:   if(estepm > stepm){ /* Yes every two year */
                   8321:     stepsize=2;
                   8322:   }
1.126     brouard  8323: 
                   8324:   hstepm=hstepm/stepm; 
                   8325:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8326:                                fractional in yp1 */
                   8327:   anprojmean=yp;
                   8328:   yp2=modf((yp1*12),&yp);
                   8329:   mprojmean=yp;
                   8330:   yp1=modf((yp2*30.5),&yp);
                   8331:   jprojmean=yp;
                   8332:   if(jprojmean==0) jprojmean=1;
                   8333:   if(mprojmean==0) jprojmean=1;
                   8334: 
1.227     brouard  8335:   i1=pow(2,cptcoveff);
1.126     brouard  8336:   if (cptcovn < 1){i1=1;}
                   8337:   
                   8338:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8339:   
                   8340:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8341:   
1.126     brouard  8342: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8343:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8344:   for(k=1; k<=i1;k++){
1.253     brouard  8345:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8346:       continue;
1.227     brouard  8347:     if(invalidvarcomb[k]){
                   8348:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8349:       continue;
                   8350:     }
                   8351:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8352:     for(j=1;j<=cptcoveff;j++) {
                   8353:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8354:     }
1.235     brouard  8355:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8356:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8357:     }
1.227     brouard  8358:     fprintf(ficresf," yearproj age");
                   8359:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8360:       for(i=1; i<=nlstate;i++)               
                   8361:        fprintf(ficresf," p%d%d",i,j);
                   8362:       fprintf(ficresf," wp.%d",j);
                   8363:     }
                   8364:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8365:       fprintf(ficresf,"\n");
                   8366:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8367:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8368:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8369:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8370:        nhstepm = nhstepm/hstepm; 
                   8371:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8372:        oldm=oldms;savm=savms;
1.268     brouard  8373:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8374:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8375:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8376:        for (h=0; h<=nhstepm; h++){
                   8377:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8378:            break;
                   8379:          }
                   8380:        }
                   8381:        fprintf(ficresf,"\n");
                   8382:        for(j=1;j<=cptcoveff;j++) 
                   8383:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8384:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8385:        
                   8386:        for(j=1; j<=nlstate+ndeath;j++) {
                   8387:          ppij=0.;
                   8388:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8389:            if (mobilav>=1)
                   8390:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8391:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8392:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8393:            }
1.268     brouard  8394:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8395:          } /* end i */
                   8396:          fprintf(ficresf," %.3f", ppij);
                   8397:        }/* end j */
1.227     brouard  8398:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8399:       } /* end agec */
1.266     brouard  8400:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8401:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8402:     } /* end yearp */
                   8403:   } /* end  k */
1.219     brouard  8404:        
1.126     brouard  8405:   fclose(ficresf);
1.215     brouard  8406:   printf("End of Computing forecasting \n");
                   8407:   fprintf(ficlog,"End of Computing forecasting\n");
                   8408: 
1.126     brouard  8409: }
                   8410: 
1.269     brouard  8411: /************** Back Forecasting ******************/
                   8412:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8413:   /* back1, year, month, day of starting backection
                   8414:      agemin, agemax range of age
                   8415:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8416:      anback2 year of end of backprojection (same day and month as back1).
                   8417:      prevacurrent and prev are prevalences.
1.267     brouard  8418:   */
                   8419:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8420:   double agec; /* generic age */
1.268     brouard  8421:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8422:   double *popeffectif,*popcount;
                   8423:   double ***p3mat;
                   8424:   /* double ***mobaverage; */
                   8425:   char fileresfb[FILENAMELENGTH];
                   8426:  
1.268     brouard  8427:   agelim=AGEINF;
1.267     brouard  8428:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8429:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8430:      We still use firstpass and lastpass as another selection.
                   8431:   */
                   8432:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8433:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8434: 
                   8435:   /*Do we need to compute prevalence again?*/
                   8436: 
                   8437:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8438:   
                   8439:   strcpy(fileresfb,"FB_");
                   8440:   strcat(fileresfb,fileresu);
                   8441:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8442:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8443:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8444:   }
                   8445:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8446:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8447:   
                   8448:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8449:   
                   8450:    
                   8451:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8452:   if (stepm<=12) stepsize=1;
                   8453:   if(estepm < stepm){
                   8454:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8455:   }
1.270     brouard  8456:   else{
                   8457:     hstepm=estepm;   
                   8458:   }
                   8459:   if(estepm >= stepm){ /* Yes every two year */
                   8460:     stepsize=2;
                   8461:   }
1.267     brouard  8462:   
                   8463:   hstepm=hstepm/stepm;
                   8464:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8465:                                fractional in yp1 */
                   8466:   anprojmean=yp;
                   8467:   yp2=modf((yp1*12),&yp);
                   8468:   mprojmean=yp;
                   8469:   yp1=modf((yp2*30.5),&yp);
                   8470:   jprojmean=yp;
                   8471:   if(jprojmean==0) jprojmean=1;
                   8472:   if(mprojmean==0) jprojmean=1;
                   8473:   
                   8474:   i1=pow(2,cptcoveff);
                   8475:   if (cptcovn < 1){i1=1;}
                   8476:   
                   8477:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8478:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8479:   
                   8480:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8481:   
                   8482:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8483:   for(k=1; k<=i1;k++){
                   8484:     if(i1 != 1 && TKresult[nres]!= k)
                   8485:       continue;
                   8486:     if(invalidvarcomb[k]){
                   8487:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8488:       continue;
                   8489:     }
1.268     brouard  8490:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8491:     for(j=1;j<=cptcoveff;j++) {
                   8492:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8493:     }
                   8494:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8495:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8496:     }
                   8497:     fprintf(ficresfb," yearbproj age");
                   8498:     for(j=1; j<=nlstate+ndeath;j++){
                   8499:       for(i=1; i<=nlstate;i++)
1.268     brouard  8500:        fprintf(ficresfb," b%d%d",i,j);
                   8501:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8502:     }
                   8503:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8504:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8505:       fprintf(ficresfb,"\n");
                   8506:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8507:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8508:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8509:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8510:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8511:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8512:        nhstepm = nhstepm/hstepm;
                   8513:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8514:        oldm=oldms;savm=savms;
1.268     brouard  8515:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8516:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8517:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8518:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8519:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8520:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8521:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8522:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8523:            break;
                   8524:          }
                   8525:        }
                   8526:        fprintf(ficresfb,"\n");
                   8527:        for(j=1;j<=cptcoveff;j++)
                   8528:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8529:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8530:        for(i=1; i<=nlstate+ndeath;i++) {
                   8531:          ppij=0.;ppi=0.;
                   8532:          for(j=1; j<=nlstate;j++) {
                   8533:            /* if (mobilav==1) */
1.269     brouard  8534:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8535:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8536:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8537:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8538:              /* else { */
                   8539:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8540:              /* } */
1.268     brouard  8541:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8542:          } /* end j */
                   8543:          if(ppi <0.99){
                   8544:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8545:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8546:          }
                   8547:          fprintf(ficresfb," %.3f", ppij);
                   8548:        }/* end j */
1.267     brouard  8549:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8550:       } /* end agec */
                   8551:     } /* end yearp */
                   8552:   } /* end k */
1.217     brouard  8553:   
1.267     brouard  8554:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8555:   
1.267     brouard  8556:   fclose(ficresfb);
                   8557:   printf("End of Computing Back forecasting \n");
                   8558:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8559:        
1.267     brouard  8560: }
1.217     brouard  8561: 
1.269     brouard  8562: /* Variance of prevalence limit: varprlim */
                   8563:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288   ! brouard  8564:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8565:  
                   8566:    char fileresvpl[FILENAMELENGTH];  
                   8567:    FILE *ficresvpl;
                   8568:    double **oldm, **savm;
                   8569:    double **varpl; /* Variances of prevalence limits by age */   
                   8570:    int i1, k, nres, j ;
                   8571:    
                   8572:     strcpy(fileresvpl,"VPL_");
                   8573:     strcat(fileresvpl,fileresu);
                   8574:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288   ! brouard  8575:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8576:       exit(0);
                   8577:     }
1.288   ! brouard  8578:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
        !          8579:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8580:     
                   8581:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8582:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8583:     
                   8584:     i1=pow(2,cptcoveff);
                   8585:     if (cptcovn < 1){i1=1;}
                   8586: 
                   8587:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8588:     for(k=1; k<=i1;k++){
                   8589:       if(i1 != 1 && TKresult[nres]!= k)
                   8590:        continue;
                   8591:       fprintf(ficresvpl,"\n#****** ");
                   8592:       printf("\n#****** ");
                   8593:       fprintf(ficlog,"\n#****** ");
                   8594:       for(j=1;j<=cptcoveff;j++) {
                   8595:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8596:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8597:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8598:       }
                   8599:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8600:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8601:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8602:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8603:       }        
                   8604:       fprintf(ficresvpl,"******\n");
                   8605:       printf("******\n");
                   8606:       fprintf(ficlog,"******\n");
                   8607:       
                   8608:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8609:       oldm=oldms;savm=savms;
                   8610:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8611:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8612:       /*}*/
                   8613:     }
                   8614:     
                   8615:     fclose(ficresvpl);
1.288   ! brouard  8616:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
        !          8617:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8618: 
                   8619:  }
                   8620: /* Variance of back prevalence: varbprlim */
                   8621:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8622:       /*------- Variance of back (stable) prevalence------*/
                   8623: 
                   8624:    char fileresvbl[FILENAMELENGTH];  
                   8625:    FILE  *ficresvbl;
                   8626: 
                   8627:    double **oldm, **savm;
                   8628:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8629:    int i1, k, nres, j ;
                   8630: 
                   8631:    strcpy(fileresvbl,"VBL_");
                   8632:    strcat(fileresvbl,fileresu);
                   8633:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8634:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8635:      exit(0);
                   8636:    }
                   8637:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8638:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8639:    
                   8640:    
                   8641:    i1=pow(2,cptcoveff);
                   8642:    if (cptcovn < 1){i1=1;}
                   8643:    
                   8644:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8645:      for(k=1; k<=i1;k++){
                   8646:        if(i1 != 1 && TKresult[nres]!= k)
                   8647:         continue;
                   8648:        fprintf(ficresvbl,"\n#****** ");
                   8649:        printf("\n#****** ");
                   8650:        fprintf(ficlog,"\n#****** ");
                   8651:        for(j=1;j<=cptcoveff;j++) {
                   8652:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8653:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8654:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8655:        }
                   8656:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8657:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8658:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8659:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8660:        }
                   8661:        fprintf(ficresvbl,"******\n");
                   8662:        printf("******\n");
                   8663:        fprintf(ficlog,"******\n");
                   8664:        
                   8665:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8666:        oldm=oldms;savm=savms;
                   8667:        
                   8668:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8669:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8670:        /*}*/
                   8671:      }
                   8672:    
                   8673:    fclose(ficresvbl);
                   8674:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8675:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8676: 
                   8677:  } /* End of varbprlim */
                   8678: 
1.126     brouard  8679: /************** Forecasting *****not tested NB*************/
1.227     brouard  8680: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8681:   
1.227     brouard  8682: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8683: /*   int *popage; */
                   8684: /*   double calagedatem, agelim, kk1, kk2; */
                   8685: /*   double *popeffectif,*popcount; */
                   8686: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8687: /*   /\* double ***mobaverage; *\/ */
                   8688: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8689: 
1.227     brouard  8690: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8691: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8692: /*   agelim=AGESUP; */
                   8693: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8694:   
1.227     brouard  8695: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8696:   
                   8697:   
1.227     brouard  8698: /*   strcpy(filerespop,"POP_");  */
                   8699: /*   strcat(filerespop,fileresu); */
                   8700: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8701: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8702: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8703: /*   } */
                   8704: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8705: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8706: 
1.227     brouard  8707: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8708: 
1.227     brouard  8709: /*   /\* if (mobilav!=0) { *\/ */
                   8710: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8711: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8712: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8713: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8714: /*   /\*   } *\/ */
                   8715: /*   /\* } *\/ */
1.126     brouard  8716: 
1.227     brouard  8717: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8718: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8719:   
1.227     brouard  8720: /*   agelim=AGESUP; */
1.126     brouard  8721:   
1.227     brouard  8722: /*   hstepm=1; */
                   8723: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8724:        
1.227     brouard  8725: /*   if (popforecast==1) { */
                   8726: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8727: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8728: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8729: /*     }  */
                   8730: /*     popage=ivector(0,AGESUP); */
                   8731: /*     popeffectif=vector(0,AGESUP); */
                   8732: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8733:     
1.227     brouard  8734: /*     i=1;    */
                   8735: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8736:     
1.227     brouard  8737: /*     imx=i; */
                   8738: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8739: /*   } */
1.218     brouard  8740:   
1.227     brouard  8741: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8742: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8743: /*       k=k+1; */
                   8744: /*       fprintf(ficrespop,"\n#******"); */
                   8745: /*       for(j=1;j<=cptcoveff;j++) { */
                   8746: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8747: /*       } */
                   8748: /*       fprintf(ficrespop,"******\n"); */
                   8749: /*       fprintf(ficrespop,"# Age"); */
                   8750: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8751: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8752:       
1.227     brouard  8753: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8754: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8755:        
1.227     brouard  8756: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8757: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8758: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8759:          
1.227     brouard  8760: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8761: /*       oldm=oldms;savm=savms; */
                   8762: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8763:          
1.227     brouard  8764: /*       for (h=0; h<=nhstepm; h++){ */
                   8765: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8766: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8767: /*         }  */
                   8768: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8769: /*           kk1=0.;kk2=0; */
                   8770: /*           for(i=1; i<=nlstate;i++) {               */
                   8771: /*             if (mobilav==1)  */
                   8772: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8773: /*             else { */
                   8774: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8775: /*             } */
                   8776: /*           } */
                   8777: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8778: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8779: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8780: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8781: /*           } */
                   8782: /*         } */
                   8783: /*         for(i=1; i<=nlstate;i++){ */
                   8784: /*           kk1=0.; */
                   8785: /*           for(j=1; j<=nlstate;j++){ */
                   8786: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8787: /*           } */
                   8788: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8789: /*         } */
1.218     brouard  8790:            
1.227     brouard  8791: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8792: /*           for(j=1; j<=nlstate;j++)  */
                   8793: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8794: /*       } */
                   8795: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8796: /*     } */
                   8797: /*       } */
1.218     brouard  8798:       
1.227     brouard  8799: /*       /\******\/ */
1.218     brouard  8800:       
1.227     brouard  8801: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8802: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8803: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8804: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8805: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8806:          
1.227     brouard  8807: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8808: /*       oldm=oldms;savm=savms; */
                   8809: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8810: /*       for (h=0; h<=nhstepm; h++){ */
                   8811: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8812: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8813: /*         }  */
                   8814: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8815: /*           kk1=0.;kk2=0; */
                   8816: /*           for(i=1; i<=nlstate;i++) {               */
                   8817: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8818: /*           } */
                   8819: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8820: /*         } */
                   8821: /*       } */
                   8822: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8823: /*     } */
                   8824: /*       } */
                   8825: /*     }  */
                   8826: /*   } */
1.218     brouard  8827:   
1.227     brouard  8828: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8829:   
1.227     brouard  8830: /*   if (popforecast==1) { */
                   8831: /*     free_ivector(popage,0,AGESUP); */
                   8832: /*     free_vector(popeffectif,0,AGESUP); */
                   8833: /*     free_vector(popcount,0,AGESUP); */
                   8834: /*   } */
                   8835: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8836: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8837: /*   fclose(ficrespop); */
                   8838: /* } /\* End of popforecast *\/ */
1.218     brouard  8839:  
1.126     brouard  8840: int fileappend(FILE *fichier, char *optionfich)
                   8841: {
                   8842:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8843:     printf("Problem with file: %s\n", optionfich);
                   8844:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8845:     return (0);
                   8846:   }
                   8847:   fflush(fichier);
                   8848:   return (1);
                   8849: }
                   8850: 
                   8851: 
                   8852: /**************** function prwizard **********************/
                   8853: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8854: {
                   8855: 
                   8856:   /* Wizard to print covariance matrix template */
                   8857: 
1.164     brouard  8858:   char ca[32], cb[32];
                   8859:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8860:   int numlinepar;
                   8861: 
                   8862:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8863:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8864:   for(i=1; i <=nlstate; i++){
                   8865:     jj=0;
                   8866:     for(j=1; j <=nlstate+ndeath; j++){
                   8867:       if(j==i) continue;
                   8868:       jj++;
                   8869:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8870:       printf("%1d%1d",i,j);
                   8871:       fprintf(ficparo,"%1d%1d",i,j);
                   8872:       for(k=1; k<=ncovmodel;k++){
                   8873:        /*        printf(" %lf",param[i][j][k]); */
                   8874:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8875:        printf(" 0.");
                   8876:        fprintf(ficparo," 0.");
                   8877:       }
                   8878:       printf("\n");
                   8879:       fprintf(ficparo,"\n");
                   8880:     }
                   8881:   }
                   8882:   printf("# Scales (for hessian or gradient estimation)\n");
                   8883:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8884:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8885:   for(i=1; i <=nlstate; i++){
                   8886:     jj=0;
                   8887:     for(j=1; j <=nlstate+ndeath; j++){
                   8888:       if(j==i) continue;
                   8889:       jj++;
                   8890:       fprintf(ficparo,"%1d%1d",i,j);
                   8891:       printf("%1d%1d",i,j);
                   8892:       fflush(stdout);
                   8893:       for(k=1; k<=ncovmodel;k++){
                   8894:        /*      printf(" %le",delti3[i][j][k]); */
                   8895:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8896:        printf(" 0.");
                   8897:        fprintf(ficparo," 0.");
                   8898:       }
                   8899:       numlinepar++;
                   8900:       printf("\n");
                   8901:       fprintf(ficparo,"\n");
                   8902:     }
                   8903:   }
                   8904:   printf("# Covariance matrix\n");
                   8905: /* # 121 Var(a12)\n\ */
                   8906: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8907: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8908: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8909: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8910: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8911: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8912: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8913:   fflush(stdout);
                   8914:   fprintf(ficparo,"# Covariance matrix\n");
                   8915:   /* # 121 Var(a12)\n\ */
                   8916:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8917:   /* #   ...\n\ */
                   8918:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8919:   
                   8920:   for(itimes=1;itimes<=2;itimes++){
                   8921:     jj=0;
                   8922:     for(i=1; i <=nlstate; i++){
                   8923:       for(j=1; j <=nlstate+ndeath; j++){
                   8924:        if(j==i) continue;
                   8925:        for(k=1; k<=ncovmodel;k++){
                   8926:          jj++;
                   8927:          ca[0]= k+'a'-1;ca[1]='\0';
                   8928:          if(itimes==1){
                   8929:            printf("#%1d%1d%d",i,j,k);
                   8930:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8931:          }else{
                   8932:            printf("%1d%1d%d",i,j,k);
                   8933:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8934:            /*  printf(" %.5le",matcov[i][j]); */
                   8935:          }
                   8936:          ll=0;
                   8937:          for(li=1;li <=nlstate; li++){
                   8938:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8939:              if(lj==li) continue;
                   8940:              for(lk=1;lk<=ncovmodel;lk++){
                   8941:                ll++;
                   8942:                if(ll<=jj){
                   8943:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8944:                  if(ll<jj){
                   8945:                    if(itimes==1){
                   8946:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8947:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8948:                    }else{
                   8949:                      printf(" 0.");
                   8950:                      fprintf(ficparo," 0.");
                   8951:                    }
                   8952:                  }else{
                   8953:                    if(itimes==1){
                   8954:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8955:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8956:                    }else{
                   8957:                      printf(" 0.");
                   8958:                      fprintf(ficparo," 0.");
                   8959:                    }
                   8960:                  }
                   8961:                }
                   8962:              } /* end lk */
                   8963:            } /* end lj */
                   8964:          } /* end li */
                   8965:          printf("\n");
                   8966:          fprintf(ficparo,"\n");
                   8967:          numlinepar++;
                   8968:        } /* end k*/
                   8969:       } /*end j */
                   8970:     } /* end i */
                   8971:   } /* end itimes */
                   8972: 
                   8973: } /* end of prwizard */
                   8974: /******************* Gompertz Likelihood ******************************/
                   8975: double gompertz(double x[])
                   8976: { 
                   8977:   double A,B,L=0.0,sump=0.,num=0.;
                   8978:   int i,n=0; /* n is the size of the sample */
                   8979: 
1.220     brouard  8980:   for (i=1;i<=imx ; i++) {
1.126     brouard  8981:     sump=sump+weight[i];
                   8982:     /*    sump=sump+1;*/
                   8983:     num=num+1;
                   8984:   }
                   8985:  
                   8986:  
                   8987:   /* for (i=0; i<=imx; i++) 
                   8988:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8989: 
                   8990:   for (i=1;i<=imx ; i++)
                   8991:     {
                   8992:       if (cens[i] == 1 && wav[i]>1)
                   8993:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8994:       
                   8995:       if (cens[i] == 0 && wav[i]>1)
                   8996:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   8997:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   8998:       
                   8999:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9000:       if (wav[i] > 1 ) { /* ??? */
                   9001:        L=L+A*weight[i];
                   9002:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9003:       }
                   9004:     }
                   9005: 
                   9006:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9007:  
                   9008:   return -2*L*num/sump;
                   9009: }
                   9010: 
1.136     brouard  9011: #ifdef GSL
                   9012: /******************* Gompertz_f Likelihood ******************************/
                   9013: double gompertz_f(const gsl_vector *v, void *params)
                   9014: { 
                   9015:   double A,B,LL=0.0,sump=0.,num=0.;
                   9016:   double *x= (double *) v->data;
                   9017:   int i,n=0; /* n is the size of the sample */
                   9018: 
                   9019:   for (i=0;i<=imx-1 ; i++) {
                   9020:     sump=sump+weight[i];
                   9021:     /*    sump=sump+1;*/
                   9022:     num=num+1;
                   9023:   }
                   9024:  
                   9025:  
                   9026:   /* for (i=0; i<=imx; i++) 
                   9027:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9028:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9029:   for (i=1;i<=imx ; i++)
                   9030:     {
                   9031:       if (cens[i] == 1 && wav[i]>1)
                   9032:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9033:       
                   9034:       if (cens[i] == 0 && wav[i]>1)
                   9035:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9036:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9037:       
                   9038:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9039:       if (wav[i] > 1 ) { /* ??? */
                   9040:        LL=LL+A*weight[i];
                   9041:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9042:       }
                   9043:     }
                   9044: 
                   9045:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9046:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9047:  
                   9048:   return -2*LL*num/sump;
                   9049: }
                   9050: #endif
                   9051: 
1.126     brouard  9052: /******************* Printing html file ***********/
1.201     brouard  9053: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9054:                  int lastpass, int stepm, int weightopt, char model[],\
                   9055:                  int imx,  double p[],double **matcov,double agemortsup){
                   9056:   int i,k;
                   9057: 
                   9058:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9059:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9060:   for (i=1;i<=2;i++) 
                   9061:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9062:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9063:   fprintf(fichtm,"</ul>");
                   9064: 
                   9065: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9066: 
                   9067:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9068: 
                   9069:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9070:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9071: 
                   9072:  
                   9073:   fflush(fichtm);
                   9074: }
                   9075: 
                   9076: /******************* Gnuplot file **************/
1.201     brouard  9077: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9078: 
                   9079:   char dirfileres[132],optfileres[132];
1.164     brouard  9080: 
1.126     brouard  9081:   int ng;
                   9082: 
                   9083: 
                   9084:   /*#ifdef windows */
                   9085:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9086:     /*#endif */
                   9087: 
                   9088: 
                   9089:   strcpy(dirfileres,optionfilefiname);
                   9090:   strcpy(optfileres,"vpl");
1.199     brouard  9091:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9092:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9093:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9094:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9095:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9096: 
                   9097: } 
                   9098: 
1.136     brouard  9099: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9100: {
1.126     brouard  9101: 
1.136     brouard  9102:   /*-------- data file ----------*/
                   9103:   FILE *fic;
                   9104:   char dummy[]="                         ";
1.240     brouard  9105:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9106:   int lstra;
1.136     brouard  9107:   int linei, month, year,iout;
                   9108:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9109:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9110:   char *stratrunc;
1.223     brouard  9111: 
1.240     brouard  9112:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9113:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9114: 
1.240     brouard  9115:   for(v=1; v <=ncovcol;v++){
                   9116:     DummyV[v]=0;
                   9117:     FixedV[v]=0;
                   9118:   }
                   9119:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9120:     DummyV[v]=1;
                   9121:     FixedV[v]=0;
                   9122:   }
                   9123:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9124:     DummyV[v]=0;
                   9125:     FixedV[v]=1;
                   9126:   }
                   9127:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9128:     DummyV[v]=1;
                   9129:     FixedV[v]=1;
                   9130:   }
                   9131:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9132:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9133:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9134:   }
1.126     brouard  9135: 
1.136     brouard  9136:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9137:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9138:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9139:   }
1.126     brouard  9140: 
1.136     brouard  9141:   i=1;
                   9142:   linei=0;
                   9143:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9144:     linei=linei+1;
                   9145:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9146:       if(line[j] == '\t')
                   9147:        line[j] = ' ';
                   9148:     }
                   9149:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9150:       ;
                   9151:     };
                   9152:     line[j+1]=0;  /* Trims blanks at end of line */
                   9153:     if(line[0]=='#'){
                   9154:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9155:       printf("Comment line\n%s\n",line);
                   9156:       continue;
                   9157:     }
                   9158:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9159:     strcpy(line, linetmp);
1.223     brouard  9160:     
                   9161:     /* Loops on waves */
                   9162:     for (j=maxwav;j>=1;j--){
                   9163:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9164:        cutv(stra, strb, line, ' '); 
                   9165:        if(strb[0]=='.') { /* Missing value */
                   9166:          lval=-1;
                   9167:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9168:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9169:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9170:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9171:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9172:            return 1;
                   9173:          }
                   9174:        }else{
                   9175:          errno=0;
                   9176:          /* what_kind_of_number(strb); */
                   9177:          dval=strtod(strb,&endptr); 
                   9178:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9179:          /* if(strb != endptr && *endptr == '\0') */
                   9180:          /*    dval=dlval; */
                   9181:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9182:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9183:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9184:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9185:            return 1;
                   9186:          }
                   9187:          cotqvar[j][iv][i]=dval; 
                   9188:          cotvar[j][ntv+iv][i]=dval; 
                   9189:        }
                   9190:        strcpy(line,stra);
1.223     brouard  9191:       }/* end loop ntqv */
1.225     brouard  9192:       
1.223     brouard  9193:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9194:        cutv(stra, strb, line, ' '); 
                   9195:        if(strb[0]=='.') { /* Missing value */
                   9196:          lval=-1;
                   9197:        }else{
                   9198:          errno=0;
                   9199:          lval=strtol(strb,&endptr,10); 
                   9200:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9201:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9202:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9203:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9204:            return 1;
                   9205:          }
                   9206:        }
                   9207:        if(lval <-1 || lval >1){
                   9208:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9209:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9210:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9211:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9212:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9213:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9214:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9215:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9216:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9217:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9218:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9219:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9220:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9221:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9222:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9223:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9224:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9225:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9226:          return 1;
                   9227:        }
                   9228:        cotvar[j][iv][i]=(double)(lval);
                   9229:        strcpy(line,stra);
1.223     brouard  9230:       }/* end loop ntv */
1.225     brouard  9231:       
1.223     brouard  9232:       /* Statuses  at wave */
1.137     brouard  9233:       cutv(stra, strb, line, ' '); 
1.223     brouard  9234:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9235:        lval=-1;
1.136     brouard  9236:       }else{
1.238     brouard  9237:        errno=0;
                   9238:        lval=strtol(strb,&endptr,10); 
                   9239:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9240:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9241:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9242:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9243:          return 1;
                   9244:        }
1.136     brouard  9245:       }
1.225     brouard  9246:       
1.136     brouard  9247:       s[j][i]=lval;
1.225     brouard  9248:       
1.223     brouard  9249:       /* Date of Interview */
1.136     brouard  9250:       strcpy(line,stra);
                   9251:       cutv(stra, strb,line,' ');
1.169     brouard  9252:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9253:       }
1.169     brouard  9254:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9255:        month=99;
                   9256:        year=9999;
1.136     brouard  9257:       }else{
1.225     brouard  9258:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9259:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9260:        return 1;
1.136     brouard  9261:       }
                   9262:       anint[j][i]= (double) year; 
                   9263:       mint[j][i]= (double)month; 
                   9264:       strcpy(line,stra);
1.223     brouard  9265:     } /* End loop on waves */
1.225     brouard  9266:     
1.223     brouard  9267:     /* Date of death */
1.136     brouard  9268:     cutv(stra, strb,line,' '); 
1.169     brouard  9269:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9270:     }
1.169     brouard  9271:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9272:       month=99;
                   9273:       year=9999;
                   9274:     }else{
1.141     brouard  9275:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9276:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9277:       return 1;
1.136     brouard  9278:     }
                   9279:     andc[i]=(double) year; 
                   9280:     moisdc[i]=(double) month; 
                   9281:     strcpy(line,stra);
                   9282:     
1.223     brouard  9283:     /* Date of birth */
1.136     brouard  9284:     cutv(stra, strb,line,' '); 
1.169     brouard  9285:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9286:     }
1.169     brouard  9287:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9288:       month=99;
                   9289:       year=9999;
                   9290:     }else{
1.141     brouard  9291:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9292:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9293:       return 1;
1.136     brouard  9294:     }
                   9295:     if (year==9999) {
1.141     brouard  9296:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9297:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9298:       return 1;
                   9299:       
1.136     brouard  9300:     }
                   9301:     annais[i]=(double)(year);
                   9302:     moisnais[i]=(double)(month); 
                   9303:     strcpy(line,stra);
1.225     brouard  9304:     
1.223     brouard  9305:     /* Sample weight */
1.136     brouard  9306:     cutv(stra, strb,line,' '); 
                   9307:     errno=0;
                   9308:     dval=strtod(strb,&endptr); 
                   9309:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9310:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9311:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9312:       fflush(ficlog);
                   9313:       return 1;
                   9314:     }
                   9315:     weight[i]=dval; 
                   9316:     strcpy(line,stra);
1.225     brouard  9317:     
1.223     brouard  9318:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9319:       cutv(stra, strb, line, ' '); 
                   9320:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9321:        lval=-1;
1.223     brouard  9322:       }else{
1.225     brouard  9323:        errno=0;
                   9324:        /* what_kind_of_number(strb); */
                   9325:        dval=strtod(strb,&endptr);
                   9326:        /* if(strb != endptr && *endptr == '\0') */
                   9327:        /*   dval=dlval; */
                   9328:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9329:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9330:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9331:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9332:          return 1;
                   9333:        }
                   9334:        coqvar[iv][i]=dval; 
1.226     brouard  9335:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9336:       }
                   9337:       strcpy(line,stra);
                   9338:     }/* end loop nqv */
1.136     brouard  9339:     
1.223     brouard  9340:     /* Covariate values */
1.136     brouard  9341:     for (j=ncovcol;j>=1;j--){
                   9342:       cutv(stra, strb,line,' '); 
1.223     brouard  9343:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9344:        lval=-1;
1.136     brouard  9345:       }else{
1.225     brouard  9346:        errno=0;
                   9347:        lval=strtol(strb,&endptr,10); 
                   9348:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9349:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9350:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9351:          return 1;
                   9352:        }
1.136     brouard  9353:       }
                   9354:       if(lval <-1 || lval >1){
1.225     brouard  9355:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9356:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9357:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9358:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9359:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9360:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9361:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9362:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9363:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9364:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9365:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9366:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9367:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9368:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9369:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9370:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9371:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9372:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9373:        return 1;
1.136     brouard  9374:       }
                   9375:       covar[j][i]=(double)(lval);
                   9376:       strcpy(line,stra);
                   9377:     }  
                   9378:     lstra=strlen(stra);
1.225     brouard  9379:     
1.136     brouard  9380:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9381:       stratrunc = &(stra[lstra-9]);
                   9382:       num[i]=atol(stratrunc);
                   9383:     }
                   9384:     else
                   9385:       num[i]=atol(stra);
                   9386:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9387:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9388:     
                   9389:     i=i+1;
                   9390:   } /* End loop reading  data */
1.225     brouard  9391:   
1.136     brouard  9392:   *imax=i-1; /* Number of individuals */
                   9393:   fclose(fic);
1.225     brouard  9394:   
1.136     brouard  9395:   return (0);
1.164     brouard  9396:   /* endread: */
1.225     brouard  9397:   printf("Exiting readdata: ");
                   9398:   fclose(fic);
                   9399:   return (1);
1.223     brouard  9400: }
1.126     brouard  9401: 
1.234     brouard  9402: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9403:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9404:   while (*p2 == ' ')
1.234     brouard  9405:     p2++; 
                   9406:   /* while ((*p1++ = *p2++) !=0) */
                   9407:   /*   ; */
                   9408:   /* do */
                   9409:   /*   while (*p2 == ' ') */
                   9410:   /*     p2++; */
                   9411:   /* while (*p1++ == *p2++); */
                   9412:   *stri=p2; 
1.145     brouard  9413: }
                   9414: 
1.235     brouard  9415: int decoderesult ( char resultline[], int nres)
1.230     brouard  9416: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9417: {
1.235     brouard  9418:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9419:   char resultsav[MAXLINE];
1.234     brouard  9420:   int resultmodel[MAXLINE];
                   9421:   int modelresult[MAXLINE];
1.230     brouard  9422:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9423: 
1.234     brouard  9424:   removefirstspace(&resultline);
1.233     brouard  9425:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9426: 
                   9427:   if (strstr(resultline,"v") !=0){
                   9428:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9429:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9430:     return 1;
                   9431:   }
                   9432:   trimbb(resultsav, resultline);
                   9433:   if (strlen(resultsav) >1){
                   9434:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9435:   }
1.253     brouard  9436:   if(j == 0){ /* Resultline but no = */
                   9437:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9438:     return (0);
                   9439:   }
                   9440:     
1.234     brouard  9441:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9442:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9443:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9444:   }
                   9445:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9446:     if(nbocc(resultsav,'=') >1){
                   9447:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9448:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9449:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9450:     }else
                   9451:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9452:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9453:     
1.230     brouard  9454:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9455:     Tvarsel[k]=atoi(strc);
                   9456:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9457:     /* cptcovsel++;     */
                   9458:     if (nbocc(stra,'=') >0)
                   9459:       strcpy(resultsav,stra); /* and analyzes it */
                   9460:   }
1.235     brouard  9461:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9462:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9463:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9464:       match=0;
1.236     brouard  9465:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9466:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9467:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9468:          match=1;
                   9469:          break;
                   9470:        }
                   9471:       }
                   9472:       if(match == 0){
                   9473:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9474:       }
                   9475:     }
                   9476:   }
1.235     brouard  9477:   /* Checking for missing or useless values in comparison of current model needs */
                   9478:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9479:     match=0;
1.235     brouard  9480:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9481:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9482:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9483:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9484:          ++match;
                   9485:        }
                   9486:       }
                   9487:     }
                   9488:     if(match == 0){
                   9489:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9490:     }else if(match > 1){
                   9491:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9492:     }
                   9493:   }
1.235     brouard  9494:       
1.234     brouard  9495:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9496:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9497:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9498:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9499:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9500:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9501:   /*    1 0 0 0 */
                   9502:   /*    2 1 0 0 */
                   9503:   /*    3 0 1 0 */ 
                   9504:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9505:   /*    5 0 0 1 */
                   9506:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9507:   /*    7 0 1 1 */
                   9508:   /*    8 1 1 1 */
1.237     brouard  9509:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9510:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9511:   /* V5*age V5 known which value for nres?  */
                   9512:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9513:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9514:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9515:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9516:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9517:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9518:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9519:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9520:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9521:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9522:       k4++;;
                   9523:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9524:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9525:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9526:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9527:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9528:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9529:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9530:       k4q++;;
                   9531:     }
                   9532:   }
1.234     brouard  9533:   
1.235     brouard  9534:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9535:   return (0);
                   9536: }
1.235     brouard  9537: 
1.230     brouard  9538: int decodemodel( char model[], int lastobs)
                   9539:  /**< This routine decodes the model and returns:
1.224     brouard  9540:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9541:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9542:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9543:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9544:        * - cptcovage number of covariates with age*products =2
                   9545:        * - cptcovs number of simple covariates
                   9546:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9547:        *     which is a new column after the 9 (ncovcol) variables. 
                   9548:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9549:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9550:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9551:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9552:        */
1.136     brouard  9553: {
1.238     brouard  9554:   int i, j, k, ks, v;
1.227     brouard  9555:   int  j1, k1, k2, k3, k4;
1.136     brouard  9556:   char modelsav[80];
1.145     brouard  9557:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9558:   char *strpt;
1.136     brouard  9559: 
1.145     brouard  9560:   /*removespace(model);*/
1.136     brouard  9561:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9562:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9563:     if (strstr(model,"AGE") !=0){
1.192     brouard  9564:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9565:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9566:       return 1;
                   9567:     }
1.141     brouard  9568:     if (strstr(model,"v") !=0){
                   9569:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9570:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9571:       return 1;
                   9572:     }
1.187     brouard  9573:     strcpy(modelsav,model); 
                   9574:     if ((strpt=strstr(model,"age*age")) !=0){
                   9575:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9576:       if(strpt != model){
1.234     brouard  9577:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9578:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9579:  corresponding column of parameters.\n",model);
1.234     brouard  9580:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9581:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9582:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9583:        return 1;
1.225     brouard  9584:       }
1.187     brouard  9585:       nagesqr=1;
                   9586:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9587:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9588:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9589:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9590:       else 
1.234     brouard  9591:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9592:     }else
                   9593:       nagesqr=0;
                   9594:     if (strlen(modelsav) >1){
                   9595:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9596:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9597:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9598:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9599:                     * cst, age and age*age 
                   9600:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9601:       /* including age products which are counted in cptcovage.
                   9602:        * but the covariates which are products must be treated 
                   9603:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9604:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9605:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9606:       
                   9607:       
1.187     brouard  9608:       /*   Design
                   9609:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9610:        *  <          ncovcol=8                >
                   9611:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9612:        *   k=  1    2      3       4     5       6      7        8
                   9613:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9614:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9615:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9616:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9617:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9618:        *  Tage[++cptcovage]=k
                   9619:        *       if products, new covar are created after ncovcol with k1
                   9620:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9621:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9622:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9623:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9624:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9625:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9626:        *  <          ncovcol=8                >
                   9627:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9628:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9629:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9630:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9631:        * p Tprod[1]@2={                         6, 5}
                   9632:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9633:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9634:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9635:        *How to reorganize?
                   9636:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9637:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9638:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9639:        * Struct []
                   9640:        */
1.225     brouard  9641:       
1.187     brouard  9642:       /* This loop fills the array Tvar from the string 'model'.*/
                   9643:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9644:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9645:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9646:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9647:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9648:       /*       k=1 Tvar[1]=2 (from V2) */
                   9649:       /*       k=5 Tvar[5] */
                   9650:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9651:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9652:       /*       } */
1.198     brouard  9653:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9654:       /*
                   9655:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9656:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9657:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9658:       }
1.187     brouard  9659:       cptcovage=0;
                   9660:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9661:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9662:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9663:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9664:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9665:        /*scanf("%d",i);*/
                   9666:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9667:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9668:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9669:            /* covar is not filled and then is empty */
                   9670:            cptcovprod--;
                   9671:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9672:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9673:            Typevar[k]=1;  /* 1 for age product */
                   9674:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9675:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9676:            /*printf("stre=%s ", stre);*/
                   9677:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9678:            cptcovprod--;
                   9679:            cutl(stre,strb,strc,'V');
                   9680:            Tvar[k]=atoi(stre);
                   9681:            Typevar[k]=1;  /* 1 for age product */
                   9682:            cptcovage++;
                   9683:            Tage[cptcovage]=k;
                   9684:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9685:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9686:            cptcovn++;
                   9687:            cptcovprodnoage++;k1++;
                   9688:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9689:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9690:                                                because this model-covariate is a construction we invent a new column
                   9691:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9692:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9693:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9694:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9695:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9696:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9697:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9698:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9699:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9700:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9701:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9702:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9703:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9704:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9705:            for (i=1; i<=lastobs;i++){
                   9706:              /* Computes the new covariate which is a product of
                   9707:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9708:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9709:            }
                   9710:          } /* End age is not in the model */
                   9711:        } /* End if model includes a product */
                   9712:        else { /* no more sum */
                   9713:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9714:          /*  scanf("%d",i);*/
                   9715:          cutl(strd,strc,strb,'V');
                   9716:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9717:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9718:          Tvar[k]=atoi(strd);
                   9719:          Typevar[k]=0;  /* 0 for simple covariates */
                   9720:        }
                   9721:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9722:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9723:                                  scanf("%d",i);*/
1.187     brouard  9724:       } /* end of loop + on total covariates */
                   9725:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9726:   } /* end if strlen(model == 0) */
1.136     brouard  9727:   
                   9728:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9729:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9730:   
1.136     brouard  9731:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9732:      printf("cptcovprod=%d ", cptcovprod);
                   9733:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9734:      scanf("%d ",i);*/
                   9735: 
                   9736: 
1.230     brouard  9737: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9738:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9739: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9740:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9741:    k =           1    2   3     4       5       6      7      8        9
                   9742:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9743:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9744:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9745:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9746:          Tmodelind[combination of covar]=k;
1.225     brouard  9747: */  
                   9748: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9749:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9750:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9751:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9752:   printf("Model=%s\n\
                   9753: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9754: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9755: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9756:   fprintf(ficlog,"Model=%s\n\
                   9757: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9758: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9759: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9760:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9761:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9762:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9763:       Fixed[k]= 0;
                   9764:       Dummy[k]= 0;
1.225     brouard  9765:       ncoveff++;
1.232     brouard  9766:       ncovf++;
1.234     brouard  9767:       nsd++;
                   9768:       modell[k].maintype= FTYPE;
                   9769:       TvarsD[nsd]=Tvar[k];
                   9770:       TvarsDind[nsd]=k;
                   9771:       TvarF[ncovf]=Tvar[k];
                   9772:       TvarFind[ncovf]=k;
                   9773:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9774:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9775:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9776:       Fixed[k]= 0;
                   9777:       Dummy[k]= 0;
                   9778:       ncoveff++;
                   9779:       ncovf++;
                   9780:       modell[k].maintype= FTYPE;
                   9781:       TvarF[ncovf]=Tvar[k];
                   9782:       TvarFind[ncovf]=k;
1.230     brouard  9783:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9784:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9785:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9786:       Fixed[k]= 0;
                   9787:       Dummy[k]= 1;
1.230     brouard  9788:       nqfveff++;
1.234     brouard  9789:       modell[k].maintype= FTYPE;
                   9790:       modell[k].subtype= FQ;
                   9791:       nsq++;
                   9792:       TvarsQ[nsq]=Tvar[k];
                   9793:       TvarsQind[nsq]=k;
1.232     brouard  9794:       ncovf++;
1.234     brouard  9795:       TvarF[ncovf]=Tvar[k];
                   9796:       TvarFind[ncovf]=k;
1.231     brouard  9797:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9798:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9799:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9800:       Fixed[k]= 1;
                   9801:       Dummy[k]= 0;
1.225     brouard  9802:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9803:       modell[k].maintype= VTYPE;
                   9804:       modell[k].subtype= VD;
                   9805:       nsd++;
                   9806:       TvarsD[nsd]=Tvar[k];
                   9807:       TvarsDind[nsd]=k;
                   9808:       ncovv++; /* Only simple time varying variables */
                   9809:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9810:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9811:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9812:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9813:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9814:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9815:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9816:       Fixed[k]= 1;
                   9817:       Dummy[k]= 1;
                   9818:       nqtveff++;
                   9819:       modell[k].maintype= VTYPE;
                   9820:       modell[k].subtype= VQ;
                   9821:       ncovv++; /* Only simple time varying variables */
                   9822:       nsq++;
                   9823:       TvarsQ[nsq]=Tvar[k];
                   9824:       TvarsQind[nsq]=k;
                   9825:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9826:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9827:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9828:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9829:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9830:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9831:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9832:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9833:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9834:       ncova++;
                   9835:       TvarA[ncova]=Tvar[k];
                   9836:       TvarAind[ncova]=k;
1.231     brouard  9837:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9838:        Fixed[k]= 2;
                   9839:        Dummy[k]= 2;
                   9840:        modell[k].maintype= ATYPE;
                   9841:        modell[k].subtype= APFD;
                   9842:        /* ncoveff++; */
1.227     brouard  9843:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9844:        Fixed[k]= 2;
                   9845:        Dummy[k]= 3;
                   9846:        modell[k].maintype= ATYPE;
                   9847:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9848:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9849:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9850:        Fixed[k]= 3;
                   9851:        Dummy[k]= 2;
                   9852:        modell[k].maintype= ATYPE;
                   9853:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9854:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9855:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9856:        Fixed[k]= 3;
                   9857:        Dummy[k]= 3;
                   9858:        modell[k].maintype= ATYPE;
                   9859:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9860:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9861:       }
                   9862:     }else if (Typevar[k] == 2) {  /* product without age */
                   9863:       k1=Tposprod[k];
                   9864:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9865:        if(Tvard[k1][2] <=ncovcol){
                   9866:          Fixed[k]= 1;
                   9867:          Dummy[k]= 0;
                   9868:          modell[k].maintype= FTYPE;
                   9869:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9870:          ncovf++; /* Fixed variables without age */
                   9871:          TvarF[ncovf]=Tvar[k];
                   9872:          TvarFind[ncovf]=k;
                   9873:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9874:          Fixed[k]= 0;  /* or 2 ?*/
                   9875:          Dummy[k]= 1;
                   9876:          modell[k].maintype= FTYPE;
                   9877:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9878:          ncovf++; /* Varying variables without age */
                   9879:          TvarF[ncovf]=Tvar[k];
                   9880:          TvarFind[ncovf]=k;
                   9881:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9882:          Fixed[k]= 1;
                   9883:          Dummy[k]= 0;
                   9884:          modell[k].maintype= VTYPE;
                   9885:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9886:          ncovv++; /* Varying variables without age */
                   9887:          TvarV[ncovv]=Tvar[k];
                   9888:          TvarVind[ncovv]=k;
                   9889:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9890:          Fixed[k]= 1;
                   9891:          Dummy[k]= 1;
                   9892:          modell[k].maintype= VTYPE;
                   9893:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9894:          ncovv++; /* Varying variables without age */
                   9895:          TvarV[ncovv]=Tvar[k];
                   9896:          TvarVind[ncovv]=k;
                   9897:        }
1.227     brouard  9898:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9899:        if(Tvard[k1][2] <=ncovcol){
                   9900:          Fixed[k]= 0;  /* or 2 ?*/
                   9901:          Dummy[k]= 1;
                   9902:          modell[k].maintype= FTYPE;
                   9903:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9904:          ncovf++; /* Fixed variables without age */
                   9905:          TvarF[ncovf]=Tvar[k];
                   9906:          TvarFind[ncovf]=k;
                   9907:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9908:          Fixed[k]= 1;
                   9909:          Dummy[k]= 1;
                   9910:          modell[k].maintype= VTYPE;
                   9911:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9912:          ncovv++; /* Varying variables without age */
                   9913:          TvarV[ncovv]=Tvar[k];
                   9914:          TvarVind[ncovv]=k;
                   9915:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9916:          Fixed[k]= 1;
                   9917:          Dummy[k]= 1;
                   9918:          modell[k].maintype= VTYPE;
                   9919:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9920:          ncovv++; /* Varying variables without age */
                   9921:          TvarV[ncovv]=Tvar[k];
                   9922:          TvarVind[ncovv]=k;
                   9923:          ncovv++; /* Varying variables without age */
                   9924:          TvarV[ncovv]=Tvar[k];
                   9925:          TvarVind[ncovv]=k;
                   9926:        }
1.227     brouard  9927:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9928:        if(Tvard[k1][2] <=ncovcol){
                   9929:          Fixed[k]= 1;
                   9930:          Dummy[k]= 1;
                   9931:          modell[k].maintype= VTYPE;
                   9932:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9933:          ncovv++; /* Varying variables without age */
                   9934:          TvarV[ncovv]=Tvar[k];
                   9935:          TvarVind[ncovv]=k;
                   9936:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9937:          Fixed[k]= 1;
                   9938:          Dummy[k]= 1;
                   9939:          modell[k].maintype= VTYPE;
                   9940:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9941:          ncovv++; /* Varying variables without age */
                   9942:          TvarV[ncovv]=Tvar[k];
                   9943:          TvarVind[ncovv]=k;
                   9944:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9945:          Fixed[k]= 1;
                   9946:          Dummy[k]= 0;
                   9947:          modell[k].maintype= VTYPE;
                   9948:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9949:          ncovv++; /* Varying variables without age */
                   9950:          TvarV[ncovv]=Tvar[k];
                   9951:          TvarVind[ncovv]=k;
                   9952:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9953:          Fixed[k]= 1;
                   9954:          Dummy[k]= 1;
                   9955:          modell[k].maintype= VTYPE;
                   9956:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9957:          ncovv++; /* Varying variables without age */
                   9958:          TvarV[ncovv]=Tvar[k];
                   9959:          TvarVind[ncovv]=k;
                   9960:        }
1.227     brouard  9961:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9962:        if(Tvard[k1][2] <=ncovcol){
                   9963:          Fixed[k]= 1;
                   9964:          Dummy[k]= 1;
                   9965:          modell[k].maintype= VTYPE;
                   9966:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9967:          ncovv++; /* Varying variables without age */
                   9968:          TvarV[ncovv]=Tvar[k];
                   9969:          TvarVind[ncovv]=k;
                   9970:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9971:          Fixed[k]= 1;
                   9972:          Dummy[k]= 1;
                   9973:          modell[k].maintype= VTYPE;
                   9974:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9975:          ncovv++; /* Varying variables without age */
                   9976:          TvarV[ncovv]=Tvar[k];
                   9977:          TvarVind[ncovv]=k;
                   9978:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9979:          Fixed[k]= 1;
                   9980:          Dummy[k]= 1;
                   9981:          modell[k].maintype= VTYPE;
                   9982:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9983:          ncovv++; /* Varying variables without age */
                   9984:          TvarV[ncovv]=Tvar[k];
                   9985:          TvarVind[ncovv]=k;
                   9986:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9987:          Fixed[k]= 1;
                   9988:          Dummy[k]= 1;
                   9989:          modell[k].maintype= VTYPE;
                   9990:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9991:          ncovv++; /* Varying variables without age */
                   9992:          TvarV[ncovv]=Tvar[k];
                   9993:          TvarVind[ncovv]=k;
                   9994:        }
1.227     brouard  9995:       }else{
1.240     brouard  9996:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9997:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   9998:       } /*end k1*/
1.225     brouard  9999:     }else{
1.226     brouard  10000:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10001:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10002:     }
1.227     brouard  10003:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10004:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10005:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10006:   }
                   10007:   /* Searching for doublons in the model */
                   10008:   for(k1=1; k1<= cptcovt;k1++){
                   10009:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10010:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10011:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10012:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10013:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10014:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10015:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10016:            return(1);
                   10017:          }
                   10018:        }else if (Typevar[k1] ==2){
                   10019:          k3=Tposprod[k1];
                   10020:          k4=Tposprod[k2];
                   10021:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10022:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10023:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10024:            return(1);
                   10025:          }
                   10026:        }
1.227     brouard  10027:       }
                   10028:     }
1.225     brouard  10029:   }
                   10030:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10031:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10032:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10033:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10034:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10035:   /*endread:*/
1.225     brouard  10036:   printf("Exiting decodemodel: ");
                   10037:   return (1);
1.136     brouard  10038: }
                   10039: 
1.169     brouard  10040: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10041: {/* Check ages at death */
1.136     brouard  10042:   int i, m;
1.218     brouard  10043:   int firstone=0;
                   10044:   
1.136     brouard  10045:   for (i=1; i<=imx; i++) {
                   10046:     for(m=2; (m<= maxwav); m++) {
                   10047:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10048:        anint[m][i]=9999;
1.216     brouard  10049:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10050:          s[m][i]=-1;
1.136     brouard  10051:       }
                   10052:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10053:        *nberr = *nberr + 1;
1.218     brouard  10054:        if(firstone == 0){
                   10055:          firstone=1;
1.260     brouard  10056:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10057:        }
1.262     brouard  10058:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10059:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10060:       }
                   10061:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10062:        (*nberr)++;
1.259     brouard  10063:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10064:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10065:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10066:       }
                   10067:     }
                   10068:   }
                   10069: 
                   10070:   for (i=1; i<=imx; i++)  {
                   10071:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10072:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10073:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10074:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10075:          if(agedc[i]>0){
                   10076:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10077:              agev[m][i]=agedc[i];
1.214     brouard  10078:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10079:            }else {
1.136     brouard  10080:              if ((int)andc[i]!=9999){
                   10081:                nbwarn++;
                   10082:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10083:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10084:                agev[m][i]=-1;
                   10085:              }
                   10086:            }
1.169     brouard  10087:          } /* agedc > 0 */
1.214     brouard  10088:        } /* end if */
1.136     brouard  10089:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10090:                                 years but with the precision of a month */
                   10091:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10092:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10093:            agev[m][i]=1;
                   10094:          else if(agev[m][i] < *agemin){ 
                   10095:            *agemin=agev[m][i];
                   10096:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10097:          }
                   10098:          else if(agev[m][i] >*agemax){
                   10099:            *agemax=agev[m][i];
1.156     brouard  10100:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10101:          }
                   10102:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10103:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10104:        } /* en if 9*/
1.136     brouard  10105:        else { /* =9 */
1.214     brouard  10106:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10107:          agev[m][i]=1;
                   10108:          s[m][i]=-1;
                   10109:        }
                   10110:       }
1.214     brouard  10111:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10112:        agev[m][i]=1;
1.214     brouard  10113:       else{
                   10114:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10115:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10116:        agev[m][i]=0;
                   10117:       }
                   10118:     } /* End for lastpass */
                   10119:   }
1.136     brouard  10120:     
                   10121:   for (i=1; i<=imx; i++)  {
                   10122:     for(m=firstpass; (m<=lastpass); m++){
                   10123:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10124:        (*nberr)++;
1.136     brouard  10125:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10126:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10127:        return 1;
                   10128:       }
                   10129:     }
                   10130:   }
                   10131: 
                   10132:   /*for (i=1; i<=imx; i++){
                   10133:   for (m=firstpass; (m<lastpass); m++){
                   10134:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10135: }
                   10136: 
                   10137: }*/
                   10138: 
                   10139: 
1.139     brouard  10140:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10141:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10142: 
                   10143:   return (0);
1.164     brouard  10144:  /* endread:*/
1.136     brouard  10145:     printf("Exiting calandcheckages: ");
                   10146:     return (1);
                   10147: }
                   10148: 
1.172     brouard  10149: #if defined(_MSC_VER)
                   10150: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10151: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10152: //#include "stdafx.h"
                   10153: //#include <stdio.h>
                   10154: //#include <tchar.h>
                   10155: //#include <windows.h>
                   10156: //#include <iostream>
                   10157: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10158: 
                   10159: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10160: 
                   10161: BOOL IsWow64()
                   10162: {
                   10163:        BOOL bIsWow64 = FALSE;
                   10164: 
                   10165:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10166:        //  (HANDLE, PBOOL);
                   10167: 
                   10168:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10169: 
                   10170:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10171:        const char funcName[] = "IsWow64Process";
                   10172:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10173:                GetProcAddress(module, funcName);
                   10174: 
                   10175:        if (NULL != fnIsWow64Process)
                   10176:        {
                   10177:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10178:                        &bIsWow64))
                   10179:                        //throw std::exception("Unknown error");
                   10180:                        printf("Unknown error\n");
                   10181:        }
                   10182:        return bIsWow64 != FALSE;
                   10183: }
                   10184: #endif
1.177     brouard  10185: 
1.191     brouard  10186: void syscompilerinfo(int logged)
1.167     brouard  10187:  {
                   10188:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10189:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10190:    /* /GS /W3 /Gy
                   10191:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10192:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10193:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10194:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10195:    */ 
                   10196:    /* 64 bits */
1.185     brouard  10197:    /*
                   10198:      /GS /W3 /Gy
                   10199:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10200:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10201:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10202:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10203:    /* Optimization are useless and O3 is slower than O2 */
                   10204:    /*
                   10205:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10206:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10207:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10208:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10209:    */
1.186     brouard  10210:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10211:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10212:       /PDB:"visual studio
                   10213:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10214:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10215:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10216:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10217:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10218:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10219:       uiAccess='false'"
                   10220:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10221:       /NOLOGO /TLBID:1
                   10222:    */
1.177     brouard  10223: #if defined __INTEL_COMPILER
1.178     brouard  10224: #if defined(__GNUC__)
                   10225:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10226: #endif
1.177     brouard  10227: #elif defined(__GNUC__) 
1.179     brouard  10228: #ifndef  __APPLE__
1.174     brouard  10229: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10230: #endif
1.177     brouard  10231:    struct utsname sysInfo;
1.178     brouard  10232:    int cross = CROSS;
                   10233:    if (cross){
                   10234:           printf("Cross-");
1.191     brouard  10235:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10236:    }
1.174     brouard  10237: #endif
                   10238: 
1.171     brouard  10239: #include <stdint.h>
1.178     brouard  10240: 
1.191     brouard  10241:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10242: #if defined(__clang__)
1.191     brouard  10243:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10244: #endif
                   10245: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10246:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10247: #endif
                   10248: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10249:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10250: #endif
                   10251: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10252:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10253: #endif
                   10254: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10255:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10256: #endif
                   10257: #if defined(_MSC_VER)
1.191     brouard  10258:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10259: #endif
                   10260: #if defined(__PGI)
1.191     brouard  10261:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10262: #endif
                   10263: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10264:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10265: #endif
1.191     brouard  10266:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10267:    
1.167     brouard  10268: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10269: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10270:     // Windows (x64 and x86)
1.191     brouard  10271:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10272: #elif __unix__ // all unices, not all compilers
                   10273:     // Unix
1.191     brouard  10274:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10275: #elif __linux__
                   10276:     // linux
1.191     brouard  10277:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10278: #elif __APPLE__
1.174     brouard  10279:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10280:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10281: #endif
                   10282: 
                   10283: /*  __MINGW32__          */
                   10284: /*  __CYGWIN__  */
                   10285: /* __MINGW64__  */
                   10286: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10287: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10288: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10289: /* _WIN64  // Defined for applications for Win64. */
                   10290: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10291: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10292: 
1.167     brouard  10293: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10294:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10295: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10296:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10297: #else
1.191     brouard  10298:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10299: #endif
                   10300: 
1.169     brouard  10301: #if defined(__GNUC__)
                   10302: # if defined(__GNUC_PATCHLEVEL__)
                   10303: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10304:                             + __GNUC_MINOR__ * 100 \
                   10305:                             + __GNUC_PATCHLEVEL__)
                   10306: # else
                   10307: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10308:                             + __GNUC_MINOR__ * 100)
                   10309: # endif
1.174     brouard  10310:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10311:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10312: 
                   10313:    if (uname(&sysInfo) != -1) {
                   10314:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10315:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10316:    }
                   10317:    else
                   10318:       perror("uname() error");
1.179     brouard  10319:    //#ifndef __INTEL_COMPILER 
                   10320: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10321:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10322:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10323: #endif
1.169     brouard  10324: #endif
1.172     brouard  10325: 
1.286     brouard  10326:    //   void main ()
1.172     brouard  10327:    //   {
1.169     brouard  10328: #if defined(_MSC_VER)
1.174     brouard  10329:    if (IsWow64()){
1.191     brouard  10330:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10331:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10332:    }
                   10333:    else{
1.191     brouard  10334:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10335:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10336:    }
1.172     brouard  10337:    //     printf("\nPress Enter to continue...");
                   10338:    //     getchar();
                   10339:    //   }
                   10340: 
1.169     brouard  10341: #endif
                   10342:    
1.167     brouard  10343: 
1.219     brouard  10344: }
1.136     brouard  10345: 
1.219     brouard  10346: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288   ! brouard  10347:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10348:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10349:   /* double ftolpl = 1.e-10; */
1.180     brouard  10350:   double age, agebase, agelim;
1.203     brouard  10351:   double tot;
1.180     brouard  10352: 
1.202     brouard  10353:   strcpy(filerespl,"PL_");
                   10354:   strcat(filerespl,fileresu);
                   10355:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288   ! brouard  10356:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
        !          10357:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10358:   }
1.288   ! brouard  10359:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
        !          10360:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10361:   pstamp(ficrespl);
1.288   ! brouard  10362:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10363:   fprintf(ficrespl,"#Age ");
                   10364:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10365:   fprintf(ficrespl,"\n");
1.180     brouard  10366:   
1.219     brouard  10367:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10368: 
1.219     brouard  10369:   agebase=ageminpar;
                   10370:   agelim=agemaxpar;
1.180     brouard  10371: 
1.227     brouard  10372:   /* i1=pow(2,ncoveff); */
1.234     brouard  10373:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10374:   if (cptcovn < 1){i1=1;}
1.180     brouard  10375: 
1.238     brouard  10376:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10377:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10378:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10379:        continue;
1.235     brouard  10380: 
1.238     brouard  10381:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10382:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10383:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10384:       /* k=k+1; */
                   10385:       /* to clean */
                   10386:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10387:       fprintf(ficrespl,"#******");
                   10388:       printf("#******");
                   10389:       fprintf(ficlog,"#******");
                   10390:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10391:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10392:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10393:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10394:       }
                   10395:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10396:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10397:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10398:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10399:       }
                   10400:       fprintf(ficrespl,"******\n");
                   10401:       printf("******\n");
                   10402:       fprintf(ficlog,"******\n");
                   10403:       if(invalidvarcomb[k]){
                   10404:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10405:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10406:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10407:        continue;
                   10408:       }
1.219     brouard  10409: 
1.238     brouard  10410:       fprintf(ficrespl,"#Age ");
                   10411:       for(j=1;j<=cptcoveff;j++) {
                   10412:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10413:       }
                   10414:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10415:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10416:     
1.238     brouard  10417:       for (age=agebase; age<=agelim; age++){
                   10418:        /* for (age=agebase; age<=agebase; age++){ */
                   10419:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10420:        fprintf(ficrespl,"%.0f ",age );
                   10421:        for(j=1;j<=cptcoveff;j++)
                   10422:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10423:        tot=0.;
                   10424:        for(i=1; i<=nlstate;i++){
                   10425:          tot +=  prlim[i][i];
                   10426:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10427:        }
                   10428:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10429:       } /* Age */
                   10430:       /* was end of cptcod */
                   10431:     } /* cptcov */
                   10432:   } /* nres */
1.219     brouard  10433:   return 0;
1.180     brouard  10434: }
                   10435: 
1.218     brouard  10436: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288   ! brouard  10437:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10438:        
                   10439:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10440:    * at any age between ageminpar and agemaxpar
                   10441:         */
1.235     brouard  10442:   int i, j, k, i1, nres=0 ;
1.217     brouard  10443:   /* double ftolpl = 1.e-10; */
                   10444:   double age, agebase, agelim;
                   10445:   double tot;
1.218     brouard  10446:   /* double ***mobaverage; */
                   10447:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10448: 
                   10449:   strcpy(fileresplb,"PLB_");
                   10450:   strcat(fileresplb,fileresu);
                   10451:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288   ! brouard  10452:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
        !          10453:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10454:   }
1.288   ! brouard  10455:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
        !          10456:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10457:   pstamp(ficresplb);
1.288   ! brouard  10458:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10459:   fprintf(ficresplb,"#Age ");
                   10460:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10461:   fprintf(ficresplb,"\n");
                   10462:   
1.218     brouard  10463:   
                   10464:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10465:   
                   10466:   agebase=ageminpar;
                   10467:   agelim=agemaxpar;
                   10468:   
                   10469:   
1.227     brouard  10470:   i1=pow(2,cptcoveff);
1.218     brouard  10471:   if (cptcovn < 1){i1=1;}
1.227     brouard  10472:   
1.238     brouard  10473:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10474:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10475:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10476:        continue;
                   10477:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10478:       fprintf(ficresplb,"#******");
                   10479:       printf("#******");
                   10480:       fprintf(ficlog,"#******");
                   10481:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10482:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10483:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10484:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10485:       }
                   10486:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10487:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10488:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10489:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10490:       }
                   10491:       fprintf(ficresplb,"******\n");
                   10492:       printf("******\n");
                   10493:       fprintf(ficlog,"******\n");
                   10494:       if(invalidvarcomb[k]){
                   10495:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10496:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10497:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10498:        continue;
                   10499:       }
1.218     brouard  10500:     
1.238     brouard  10501:       fprintf(ficresplb,"#Age ");
                   10502:       for(j=1;j<=cptcoveff;j++) {
                   10503:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10504:       }
                   10505:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10506:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10507:     
                   10508:     
1.238     brouard  10509:       for (age=agebase; age<=agelim; age++){
                   10510:        /* for (age=agebase; age<=agebase; age++){ */
                   10511:        if(mobilavproj > 0){
                   10512:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10513:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10514:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10515:        }else if (mobilavproj == 0){
                   10516:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10517:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10518:          exit(1);
                   10519:        }else{
                   10520:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10521:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10522:          /* printf("TOTOT\n"); */
                   10523:           /* exit(1); */
1.238     brouard  10524:        }
                   10525:        fprintf(ficresplb,"%.0f ",age );
                   10526:        for(j=1;j<=cptcoveff;j++)
                   10527:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10528:        tot=0.;
                   10529:        for(i=1; i<=nlstate;i++){
                   10530:          tot +=  bprlim[i][i];
                   10531:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10532:        }
                   10533:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10534:       } /* Age */
                   10535:       /* was end of cptcod */
1.255     brouard  10536:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10537:     } /* end of any combination */
                   10538:   } /* end of nres */  
1.218     brouard  10539:   /* hBijx(p, bage, fage); */
                   10540:   /* fclose(ficrespijb); */
                   10541:   
                   10542:   return 0;
1.217     brouard  10543: }
1.218     brouard  10544:  
1.180     brouard  10545: int hPijx(double *p, int bage, int fage){
                   10546:     /*------------- h Pij x at various ages ------------*/
                   10547: 
                   10548:   int stepsize;
                   10549:   int agelim;
                   10550:   int hstepm;
                   10551:   int nhstepm;
1.235     brouard  10552:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10553: 
                   10554:   double agedeb;
                   10555:   double ***p3mat;
                   10556: 
1.201     brouard  10557:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10558:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10559:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10560:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10561:     }
                   10562:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10563:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10564:   
                   10565:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10566:     /*if (stepm<=24) stepsize=2;*/
                   10567: 
                   10568:     agelim=AGESUP;
                   10569:     hstepm=stepsize*YEARM; /* Every year of age */
                   10570:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10571:                
1.180     brouard  10572:     /* hstepm=1;   aff par mois*/
                   10573:     pstamp(ficrespij);
                   10574:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10575:     i1= pow(2,cptcoveff);
1.218     brouard  10576:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10577:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10578:                /*      k=k+1;  */
1.235     brouard  10579:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10580:     for(k=1; k<=i1;k++){
1.253     brouard  10581:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10582:        continue;
1.183     brouard  10583:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10584:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10585:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10586:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10587:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10588:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10589:       }
1.183     brouard  10590:       fprintf(ficrespij,"******\n");
                   10591:       
                   10592:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10593:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10594:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10595:        
                   10596:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10597:        
1.183     brouard  10598:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10599:        oldm=oldms;savm=savms;
1.235     brouard  10600:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10601:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10602:        for(i=1; i<=nlstate;i++)
                   10603:          for(j=1; j<=nlstate+ndeath;j++)
                   10604:            fprintf(ficrespij," %1d-%1d",i,j);
                   10605:        fprintf(ficrespij,"\n");
                   10606:        for (h=0; h<=nhstepm; h++){
                   10607:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10608:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10609:          for(i=1; i<=nlstate;i++)
                   10610:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10611:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10612:          fprintf(ficrespij,"\n");
                   10613:        }
1.183     brouard  10614:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10615:        fprintf(ficrespij,"\n");
                   10616:       }
1.180     brouard  10617:       /*}*/
                   10618:     }
1.218     brouard  10619:     return 0;
1.180     brouard  10620: }
1.218     brouard  10621:  
                   10622:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10623:     /*------------- h Bij x at various ages ------------*/
                   10624: 
                   10625:   int stepsize;
1.218     brouard  10626:   /* int agelim; */
                   10627:        int ageminl;
1.217     brouard  10628:   int hstepm;
                   10629:   int nhstepm;
1.238     brouard  10630:   int h, i, i1, j, k, nres;
1.218     brouard  10631:        
1.217     brouard  10632:   double agedeb;
                   10633:   double ***p3mat;
1.218     brouard  10634:        
                   10635:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10636:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10637:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10638:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10639:   }
                   10640:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10641:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10642:   
                   10643:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10644:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10645:   
1.218     brouard  10646:   /* agelim=AGESUP; */
                   10647:   ageminl=30;
                   10648:   hstepm=stepsize*YEARM; /* Every year of age */
                   10649:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10650:   
                   10651:   /* hstepm=1;   aff par mois*/
                   10652:   pstamp(ficrespijb);
1.255     brouard  10653:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10654:   i1= pow(2,cptcoveff);
1.218     brouard  10655:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10656:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10657:   /*   k=k+1;  */
1.238     brouard  10658:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10659:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10660:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10661:        continue;
                   10662:       fprintf(ficrespijb,"\n#****** ");
                   10663:       for(j=1;j<=cptcoveff;j++)
                   10664:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10665:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10666:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10667:       }
                   10668:       fprintf(ficrespijb,"******\n");
1.264     brouard  10669:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10670:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10671:        continue;
                   10672:       }
                   10673:       
                   10674:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10675:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10676:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10677:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10678:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10679:        
                   10680:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10681:        
1.266     brouard  10682:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10683:        /* and memory limitations if stepm is small */
                   10684: 
1.238     brouard  10685:        /* oldm=oldms;savm=savms; */
                   10686:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10687:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10688:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10689:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10690:        for(i=1; i<=nlstate;i++)
                   10691:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10692:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10693:        fprintf(ficrespijb,"\n");
1.238     brouard  10694:        for (h=0; h<=nhstepm; h++){
                   10695:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10696:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10697:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10698:          for(i=1; i<=nlstate;i++)
                   10699:            for(j=1; j<=nlstate+ndeath;j++)
                   10700:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10701:          fprintf(ficrespijb,"\n");
                   10702:        }
                   10703:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10704:        fprintf(ficrespijb,"\n");
                   10705:       } /* end age deb */
                   10706:     } /* end combination */
                   10707:   } /* end nres */
1.218     brouard  10708:   return 0;
                   10709:  } /*  hBijx */
1.217     brouard  10710: 
1.180     brouard  10711: 
1.136     brouard  10712: /***********************************************/
                   10713: /**************** Main Program *****************/
                   10714: /***********************************************/
                   10715: 
                   10716: int main(int argc, char *argv[])
                   10717: {
                   10718: #ifdef GSL
                   10719:   const gsl_multimin_fminimizer_type *T;
                   10720:   size_t iteri = 0, it;
                   10721:   int rval = GSL_CONTINUE;
                   10722:   int status = GSL_SUCCESS;
                   10723:   double ssval;
                   10724: #endif
                   10725:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10726:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10727:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10728:   int jj, ll, li, lj, lk;
1.136     brouard  10729:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10730:   int num_filled;
1.136     brouard  10731:   int itimes;
                   10732:   int NDIM=2;
                   10733:   int vpopbased=0;
1.235     brouard  10734:   int nres=0;
1.258     brouard  10735:   int endishere=0;
1.277     brouard  10736:   int noffset=0;
1.274     brouard  10737:   int ncurrv=0; /* Temporary variable */
                   10738:   
1.164     brouard  10739:   char ca[32], cb[32];
1.136     brouard  10740:   /*  FILE *fichtm; *//* Html File */
                   10741:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10742:   struct stat info;
1.191     brouard  10743:   double agedeb=0.;
1.194     brouard  10744: 
                   10745:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10746:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10747: 
1.165     brouard  10748:   double fret;
1.191     brouard  10749:   double dum=0.; /* Dummy variable */
1.136     brouard  10750:   double ***p3mat;
1.218     brouard  10751:   /* double ***mobaverage; */
1.164     brouard  10752: 
                   10753:   char line[MAXLINE];
1.197     brouard  10754:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10755: 
1.234     brouard  10756:   char  modeltemp[MAXLINE];
1.230     brouard  10757:   char resultline[MAXLINE];
                   10758:   
1.136     brouard  10759:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10760:   char *tok, *val; /* pathtot */
1.136     brouard  10761:   int firstobs=1, lastobs=10;
1.195     brouard  10762:   int c,  h , cpt, c2;
1.191     brouard  10763:   int jl=0;
                   10764:   int i1, j1, jk, stepsize=0;
1.194     brouard  10765:   int count=0;
                   10766: 
1.164     brouard  10767:   int *tab; 
1.136     brouard  10768:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10769:   int backcast=0;
1.136     brouard  10770:   int mobilav=0,popforecast=0;
1.191     brouard  10771:   int hstepm=0, nhstepm=0;
1.136     brouard  10772:   int agemortsup;
                   10773:   float  sumlpop=0.;
                   10774:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10775:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10776: 
1.191     brouard  10777:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10778:   double ftolpl=FTOL;
                   10779:   double **prlim;
1.217     brouard  10780:   double **bprlim;
1.136     brouard  10781:   double ***param; /* Matrix of parameters */
1.251     brouard  10782:   double ***paramstart; /* Matrix of starting parameter values */
                   10783:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10784:   double **matcov; /* Matrix of covariance */
1.203     brouard  10785:   double **hess; /* Hessian matrix */
1.136     brouard  10786:   double ***delti3; /* Scale */
                   10787:   double *delti; /* Scale */
                   10788:   double ***eij, ***vareij;
                   10789:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10790: 
1.136     brouard  10791:   double *epj, vepp;
1.164     brouard  10792: 
1.273     brouard  10793:   double dateprev1, dateprev2;
                   10794:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10795:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10796: 
1.136     brouard  10797:   double **ximort;
1.145     brouard  10798:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10799:   int *dcwave;
                   10800: 
1.164     brouard  10801:   char z[1]="c";
1.136     brouard  10802: 
                   10803:   /*char  *strt;*/
                   10804:   char strtend[80];
1.126     brouard  10805: 
1.164     brouard  10806: 
1.126     brouard  10807: /*   setlocale (LC_ALL, ""); */
                   10808: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10809: /*   textdomain (PACKAGE); */
                   10810: /*   setlocale (LC_CTYPE, ""); */
                   10811: /*   setlocale (LC_MESSAGES, ""); */
                   10812: 
                   10813:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10814:   rstart_time = time(NULL);  
                   10815:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10816:   start_time = *localtime(&rstart_time);
1.126     brouard  10817:   curr_time=start_time;
1.157     brouard  10818:   /*tml = *localtime(&start_time.tm_sec);*/
                   10819:   /* strcpy(strstart,asctime(&tml)); */
                   10820:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10821: 
                   10822: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10823: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10824: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10825: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10826: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10827: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10828: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10829: /*   strt=asctime(&tmg); */
                   10830: /*   printf("Time(after) =%s",strstart);  */
                   10831: /*  (void) time (&time_value);
                   10832: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10833: *  tm = *localtime(&time_value);
                   10834: *  strstart=asctime(&tm);
                   10835: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10836: */
                   10837: 
                   10838:   nberr=0; /* Number of errors and warnings */
                   10839:   nbwarn=0;
1.184     brouard  10840: #ifdef WIN32
                   10841:   _getcwd(pathcd, size);
                   10842: #else
1.126     brouard  10843:   getcwd(pathcd, size);
1.184     brouard  10844: #endif
1.191     brouard  10845:   syscompilerinfo(0);
1.196     brouard  10846:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10847:   if(argc <=1){
                   10848:     printf("\nEnter the parameter file name: ");
1.205     brouard  10849:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10850:       printf("ERROR Empty parameter file name\n");
                   10851:       goto end;
                   10852:     }
1.126     brouard  10853:     i=strlen(pathr);
                   10854:     if(pathr[i-1]=='\n')
                   10855:       pathr[i-1]='\0';
1.156     brouard  10856:     i=strlen(pathr);
1.205     brouard  10857:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10858:       pathr[i-1]='\0';
1.205     brouard  10859:     }
                   10860:     i=strlen(pathr);
                   10861:     if( i==0 ){
                   10862:       printf("ERROR Empty parameter file name\n");
                   10863:       goto end;
                   10864:     }
                   10865:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10866:       printf("Pathr |%s|\n",pathr);
                   10867:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10868:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10869:       strcpy (pathtot, val);
                   10870:       if(pathr[0] == '\0') break; /* Dirty */
                   10871:     }
                   10872:   }
1.281     brouard  10873:   else if (argc<=2){
                   10874:     strcpy(pathtot,argv[1]);
                   10875:   }
1.126     brouard  10876:   else{
                   10877:     strcpy(pathtot,argv[1]);
1.281     brouard  10878:     strcpy(z,argv[2]);
                   10879:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10880:   }
                   10881:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10882:   /*cygwin_split_path(pathtot,path,optionfile);
                   10883:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10884:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10885: 
                   10886:   /* Split argv[0], imach program to get pathimach */
                   10887:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10888:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10889:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10890:  /*   strcpy(pathimach,argv[0]); */
                   10891:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10892:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10893:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10894: #ifdef WIN32
                   10895:   _chdir(path); /* Can be a relative path */
                   10896:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10897: #else
1.126     brouard  10898:   chdir(path); /* Can be a relative path */
1.184     brouard  10899:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10900: #endif
                   10901:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10902:   strcpy(command,"mkdir ");
                   10903:   strcat(command,optionfilefiname);
                   10904:   if((outcmd=system(command)) != 0){
1.169     brouard  10905:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10906:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10907:     /* fclose(ficlog); */
                   10908: /*     exit(1); */
                   10909:   }
                   10910: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10911: /*     perror("mkdir"); */
                   10912: /*   } */
                   10913: 
                   10914:   /*-------- arguments in the command line --------*/
                   10915: 
1.186     brouard  10916:   /* Main Log file */
1.126     brouard  10917:   strcat(filelog, optionfilefiname);
                   10918:   strcat(filelog,".log");    /* */
                   10919:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10920:     printf("Problem with logfile %s\n",filelog);
                   10921:     goto end;
                   10922:   }
                   10923:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10924:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10925:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10926:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10927:  path=%s \n\
                   10928:  optionfile=%s\n\
                   10929:  optionfilext=%s\n\
1.156     brouard  10930:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10931: 
1.197     brouard  10932:   syscompilerinfo(1);
1.167     brouard  10933: 
1.126     brouard  10934:   printf("Local time (at start):%s",strstart);
                   10935:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10936:   fflush(ficlog);
                   10937: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10938: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10939: 
                   10940:   /* */
                   10941:   strcpy(fileres,"r");
                   10942:   strcat(fileres, optionfilefiname);
1.201     brouard  10943:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10944:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10945:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10946: 
1.186     brouard  10947:   /* Main ---------arguments file --------*/
1.126     brouard  10948: 
                   10949:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10950:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10951:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10952:     fflush(ficlog);
1.149     brouard  10953:     /* goto end; */
                   10954:     exit(70); 
1.126     brouard  10955:   }
                   10956: 
                   10957:   strcpy(filereso,"o");
1.201     brouard  10958:   strcat(filereso,fileresu);
1.126     brouard  10959:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10960:     printf("Problem with Output resultfile: %s\n", filereso);
                   10961:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10962:     fflush(ficlog);
                   10963:     goto end;
                   10964:   }
1.278     brouard  10965:       /*-------- Rewriting parameter file ----------*/
                   10966:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10967:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10968:   strcat(rfileres,".");    /* */
                   10969:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10970:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10971:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10972:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   10973:     fflush(ficlog);
                   10974:     goto end;
                   10975:   }
                   10976:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  10977: 
1.278     brouard  10978:                                      
1.126     brouard  10979:   /* Reads comments: lines beginning with '#' */
                   10980:   numlinepar=0;
1.277     brouard  10981:   /* Is it a BOM UTF-8 Windows file? */
                   10982:   /* First parameter line */
1.197     brouard  10983:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  10984:     noffset=0;
                   10985:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   10986:     {
                   10987:       noffset=noffset+3;
                   10988:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   10989:     }
                   10990:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   10991:     {
                   10992:       noffset=noffset+2;
                   10993:       printf("# File is an UTF16BE BOM file\n");
                   10994:     }
                   10995:     else if( line[0] == 0 && line[1] == 0)
                   10996:     {
                   10997:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   10998:        noffset=noffset+4;
                   10999:        printf("# File is an UTF16BE BOM file\n");
                   11000:       }
                   11001:     } else{
                   11002:       ;/*printf(" Not a BOM file\n");*/
                   11003:     }
                   11004:   
1.197     brouard  11005:     /* If line starts with a # it is a comment */
1.277     brouard  11006:     if (line[noffset] == '#') {
1.197     brouard  11007:       numlinepar++;
                   11008:       fputs(line,stdout);
                   11009:       fputs(line,ficparo);
1.278     brouard  11010:       fputs(line,ficres);
1.197     brouard  11011:       fputs(line,ficlog);
                   11012:       continue;
                   11013:     }else
                   11014:       break;
                   11015:   }
                   11016:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11017:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11018:     if (num_filled != 5) {
                   11019:       printf("Should be 5 parameters\n");
1.283     brouard  11020:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11021:     }
1.126     brouard  11022:     numlinepar++;
1.197     brouard  11023:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11024:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11025:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11026:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11027:   }
                   11028:   /* Second parameter line */
                   11029:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11030:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11031:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11032:     if (line[0] == '#') {
                   11033:       numlinepar++;
1.283     brouard  11034:       printf("%s",line);
                   11035:       fprintf(ficres,"%s",line);
                   11036:       fprintf(ficparo,"%s",line);
                   11037:       fprintf(ficlog,"%s",line);
1.197     brouard  11038:       continue;
                   11039:     }else
                   11040:       break;
                   11041:   }
1.223     brouard  11042:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11043:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11044:     if (num_filled != 11) {
                   11045:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11046:       printf("but line=%s\n",line);
1.283     brouard  11047:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11048:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11049:     }
1.286     brouard  11050:     if( lastpass > maxwav){
                   11051:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11052:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11053:       fflush(ficlog);
                   11054:       goto end;
                   11055:     }
                   11056:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11057:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11058:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11059:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11060:   }
1.203     brouard  11061:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11062:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11063:   /* Third parameter line */
                   11064:   while(fgets(line, MAXLINE, ficpar)) {
                   11065:     /* If line starts with a # it is a comment */
                   11066:     if (line[0] == '#') {
                   11067:       numlinepar++;
1.283     brouard  11068:       printf("%s",line);
                   11069:       fprintf(ficres,"%s",line);
                   11070:       fprintf(ficparo,"%s",line);
                   11071:       fprintf(ficlog,"%s",line);
1.197     brouard  11072:       continue;
                   11073:     }else
                   11074:       break;
                   11075:   }
1.201     brouard  11076:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11077:     if (num_filled != 1){
                   11078:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11079:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11080:       model[0]='\0';
                   11081:       goto end;
                   11082:     }
                   11083:     else{
                   11084:       if (model[0]=='+'){
                   11085:        for(i=1; i<=strlen(model);i++)
                   11086:          modeltemp[i-1]=model[i];
1.201     brouard  11087:        strcpy(model,modeltemp); 
1.197     brouard  11088:       }
                   11089:     }
1.199     brouard  11090:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11091:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11092:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11093:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11094:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11095:   }
                   11096:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11097:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11098:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11099:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11100:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11101:   fflush(ficlog);
1.190     brouard  11102:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11103:   if(model[0]=='#'){
1.279     brouard  11104:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11105:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11106:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11107:     if(mle != -1){
1.279     brouard  11108:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11109:       exit(1);
                   11110:     }
                   11111:   }
1.126     brouard  11112:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11113:     ungetc(c,ficpar);
                   11114:     fgets(line, MAXLINE, ficpar);
                   11115:     numlinepar++;
1.195     brouard  11116:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11117:       z[0]=line[1];
                   11118:     }
                   11119:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11120:     fputs(line, stdout);
                   11121:     //puts(line);
1.126     brouard  11122:     fputs(line,ficparo);
                   11123:     fputs(line,ficlog);
                   11124:   }
                   11125:   ungetc(c,ficpar);
                   11126: 
                   11127:    
1.145     brouard  11128:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  11129:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   11130:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   11131:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11132:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11133:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11134:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11135:   */
                   11136:   if (strlen(model)>1) 
1.187     brouard  11137:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11138:   else
1.187     brouard  11139:     ncovmodel=2; /* Constant and age */
1.133     brouard  11140:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11141:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11142:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11143:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11144:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11145:     fflush(stdout);
                   11146:     fclose (ficlog);
                   11147:     goto end;
                   11148:   }
1.126     brouard  11149:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11150:   delti=delti3[1][1];
                   11151:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11152:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11153: /* We could also provide initial parameters values giving by simple logistic regression 
                   11154:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11155:       /* for(i=1;i<nlstate;i++){ */
                   11156:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11157:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11158:       /* } */
1.126     brouard  11159:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11160:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11161:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11162:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11163:     fclose (ficparo);
                   11164:     fclose (ficlog);
                   11165:     goto end;
                   11166:     exit(0);
1.220     brouard  11167:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11168:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11169:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11170:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11171:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11172:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11173:     hess=matrix(1,npar,1,npar);
1.220     brouard  11174:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11175:     /* Read guessed parameters */
1.126     brouard  11176:     /* Reads comments: lines beginning with '#' */
                   11177:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11178:       ungetc(c,ficpar);
                   11179:       fgets(line, MAXLINE, ficpar);
                   11180:       numlinepar++;
1.141     brouard  11181:       fputs(line,stdout);
1.126     brouard  11182:       fputs(line,ficparo);
                   11183:       fputs(line,ficlog);
                   11184:     }
                   11185:     ungetc(c,ficpar);
                   11186:     
                   11187:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11188:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11189:     for(i=1; i <=nlstate; i++){
1.234     brouard  11190:       j=0;
1.126     brouard  11191:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11192:        if(jj==i) continue;
                   11193:        j++;
                   11194:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11195:        if ((i1 != i) || (j1 != jj)){
                   11196:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11197: It might be a problem of design; if ncovcol and the model are correct\n \
                   11198: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11199:          exit(1);
                   11200:        }
                   11201:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11202:        if(mle==1)
                   11203:          printf("%1d%1d",i,jj);
                   11204:        fprintf(ficlog,"%1d%1d",i,jj);
                   11205:        for(k=1; k<=ncovmodel;k++){
                   11206:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11207:          if(mle==1){
                   11208:            printf(" %lf",param[i][j][k]);
                   11209:            fprintf(ficlog," %lf",param[i][j][k]);
                   11210:          }
                   11211:          else
                   11212:            fprintf(ficlog," %lf",param[i][j][k]);
                   11213:          fprintf(ficparo," %lf",param[i][j][k]);
                   11214:        }
                   11215:        fscanf(ficpar,"\n");
                   11216:        numlinepar++;
                   11217:        if(mle==1)
                   11218:          printf("\n");
                   11219:        fprintf(ficlog,"\n");
                   11220:        fprintf(ficparo,"\n");
1.126     brouard  11221:       }
                   11222:     }  
                   11223:     fflush(ficlog);
1.234     brouard  11224:     
1.251     brouard  11225:     /* Reads parameters values */
1.126     brouard  11226:     p=param[1][1];
1.251     brouard  11227:     pstart=paramstart[1][1];
1.126     brouard  11228:     
                   11229:     /* Reads comments: lines beginning with '#' */
                   11230:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11231:       ungetc(c,ficpar);
                   11232:       fgets(line, MAXLINE, ficpar);
                   11233:       numlinepar++;
1.141     brouard  11234:       fputs(line,stdout);
1.126     brouard  11235:       fputs(line,ficparo);
                   11236:       fputs(line,ficlog);
                   11237:     }
                   11238:     ungetc(c,ficpar);
                   11239: 
                   11240:     for(i=1; i <=nlstate; i++){
                   11241:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11242:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11243:        if ( (i1-i) * (j1-j) != 0){
                   11244:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11245:          exit(1);
                   11246:        }
                   11247:        printf("%1d%1d",i,j);
                   11248:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11249:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11250:        for(k=1; k<=ncovmodel;k++){
                   11251:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11252:          printf(" %le",delti3[i][j][k]);
                   11253:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11254:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11255:        }
                   11256:        fscanf(ficpar,"\n");
                   11257:        numlinepar++;
                   11258:        printf("\n");
                   11259:        fprintf(ficparo,"\n");
                   11260:        fprintf(ficlog,"\n");
1.126     brouard  11261:       }
                   11262:     }
                   11263:     fflush(ficlog);
1.234     brouard  11264:     
1.145     brouard  11265:     /* Reads covariance matrix */
1.126     brouard  11266:     delti=delti3[1][1];
1.220     brouard  11267:                
                   11268:                
1.126     brouard  11269:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11270:                
1.126     brouard  11271:     /* Reads comments: lines beginning with '#' */
                   11272:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11273:       ungetc(c,ficpar);
                   11274:       fgets(line, MAXLINE, ficpar);
                   11275:       numlinepar++;
1.141     brouard  11276:       fputs(line,stdout);
1.126     brouard  11277:       fputs(line,ficparo);
                   11278:       fputs(line,ficlog);
                   11279:     }
                   11280:     ungetc(c,ficpar);
1.220     brouard  11281:                
1.126     brouard  11282:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11283:     hess=matrix(1,npar,1,npar);
1.131     brouard  11284:     for(i=1; i <=npar; i++)
                   11285:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11286:                
1.194     brouard  11287:     /* Scans npar lines */
1.126     brouard  11288:     for(i=1; i <=npar; i++){
1.226     brouard  11289:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11290:       if(count != 3){
1.226     brouard  11291:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11292: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11293: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11294:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11295: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11296: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11297:        exit(1);
1.220     brouard  11298:       }else{
1.226     brouard  11299:        if(mle==1)
                   11300:          printf("%1d%1d%d",i1,j1,jk);
                   11301:       }
                   11302:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11303:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11304:       for(j=1; j <=i; j++){
1.226     brouard  11305:        fscanf(ficpar," %le",&matcov[i][j]);
                   11306:        if(mle==1){
                   11307:          printf(" %.5le",matcov[i][j]);
                   11308:        }
                   11309:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11310:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11311:       }
                   11312:       fscanf(ficpar,"\n");
                   11313:       numlinepar++;
                   11314:       if(mle==1)
1.220     brouard  11315:                                printf("\n");
1.126     brouard  11316:       fprintf(ficlog,"\n");
                   11317:       fprintf(ficparo,"\n");
                   11318:     }
1.194     brouard  11319:     /* End of read covariance matrix npar lines */
1.126     brouard  11320:     for(i=1; i <=npar; i++)
                   11321:       for(j=i+1;j<=npar;j++)
1.226     brouard  11322:        matcov[i][j]=matcov[j][i];
1.126     brouard  11323:     
                   11324:     if(mle==1)
                   11325:       printf("\n");
                   11326:     fprintf(ficlog,"\n");
                   11327:     
                   11328:     fflush(ficlog);
                   11329:     
                   11330:   }    /* End of mle != -3 */
1.218     brouard  11331:   
1.186     brouard  11332:   /*  Main data
                   11333:    */
1.126     brouard  11334:   n= lastobs;
                   11335:   num=lvector(1,n);
                   11336:   moisnais=vector(1,n);
                   11337:   annais=vector(1,n);
                   11338:   moisdc=vector(1,n);
                   11339:   andc=vector(1,n);
1.220     brouard  11340:   weight=vector(1,n);
1.126     brouard  11341:   agedc=vector(1,n);
                   11342:   cod=ivector(1,n);
1.220     brouard  11343:   for(i=1;i<=n;i++){
1.234     brouard  11344:     num[i]=0;
                   11345:     moisnais[i]=0;
                   11346:     annais[i]=0;
                   11347:     moisdc[i]=0;
                   11348:     andc[i]=0;
                   11349:     agedc[i]=0;
                   11350:     cod[i]=0;
                   11351:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11352:   }
1.126     brouard  11353:   mint=matrix(1,maxwav,1,n);
                   11354:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11355:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11356:   tab=ivector(1,NCOVMAX);
1.144     brouard  11357:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11358:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11359: 
1.136     brouard  11360:   /* Reads data from file datafile */
                   11361:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11362:     goto end;
                   11363: 
                   11364:   /* Calculation of the number of parameters from char model */
1.234     brouard  11365:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11366:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11367:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11368:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11369:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11370:   */
                   11371:   
                   11372:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11373:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11374:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11375:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11376:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11377:   TvarF=ivector(1,NCOVMAX); /*  */
                   11378:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11379:   TvarV=ivector(1,NCOVMAX); /*  */
                   11380:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11381:   TvarA=ivector(1,NCOVMAX); /*  */
                   11382:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11383:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11384:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11385:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11386:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11387:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11388:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11389:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11390:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11391: 
1.230     brouard  11392:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11393:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11394:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11395:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11396:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11397:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11398:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11399:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11400:   */
                   11401:   /* For model-covariate k tells which data-covariate to use but
                   11402:     because this model-covariate is a construction we invent a new column
                   11403:     ncovcol + k1
                   11404:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11405:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11406:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11407:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11408:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11409:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11410:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11411:   */
1.145     brouard  11412:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11413:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11414:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11415:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11416:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11417:                         4 covariates (3 plus signs)
                   11418:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11419:                      */  
1.230     brouard  11420:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11421:                                * individual dummy, fixed or varying:
                   11422:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11423:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11424:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11425:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11426:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11427:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11428:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11429:                                * individual quantitative, fixed or varying:
                   11430:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11431:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11432:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11433: /* Main decodemodel */
                   11434: 
1.187     brouard  11435: 
1.223     brouard  11436:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11437:     goto end;
                   11438: 
1.137     brouard  11439:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11440:     nbwarn++;
                   11441:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11442:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11443:   }
1.136     brouard  11444:     /*  if(mle==1){*/
1.137     brouard  11445:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11446:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11447:   }
                   11448: 
                   11449:     /*-calculation of age at interview from date of interview and age at death -*/
                   11450:   agev=matrix(1,maxwav,1,imx);
                   11451: 
                   11452:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11453:     goto end;
                   11454: 
1.126     brouard  11455: 
1.136     brouard  11456:   agegomp=(int)agemin;
                   11457:   free_vector(moisnais,1,n);
                   11458:   free_vector(annais,1,n);
1.126     brouard  11459:   /* free_matrix(mint,1,maxwav,1,n);
                   11460:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11461:   /* free_vector(moisdc,1,n); */
                   11462:   /* free_vector(andc,1,n); */
1.145     brouard  11463:   /* */
                   11464:   
1.126     brouard  11465:   wav=ivector(1,imx);
1.214     brouard  11466:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11467:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11468:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11469:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11470:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11471:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11472:    
                   11473:   /* Concatenates waves */
1.214     brouard  11474:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11475:      Death is a valid wave (if date is known).
                   11476:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11477:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11478:      and mw[mi+1][i]. dh depends on stepm.
                   11479:   */
                   11480: 
1.126     brouard  11481:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11482:   /* Concatenates waves */
1.145     brouard  11483:  
1.215     brouard  11484:   free_vector(moisdc,1,n);
                   11485:   free_vector(andc,1,n);
                   11486: 
1.126     brouard  11487:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11488:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11489:   ncodemax[1]=1;
1.145     brouard  11490:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11491:   cptcoveff=0;
1.220     brouard  11492:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11493:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11494:   }
                   11495:   
                   11496:   ncovcombmax=pow(2,cptcoveff);
                   11497:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11498:   for(i=1;i<ncovcombmax;i++)
                   11499:     invalidvarcomb[i]=0;
                   11500:   
1.211     brouard  11501:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11502:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11503:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11504:   
1.200     brouard  11505:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11506:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11507:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11508:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11509:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11510:    * (currently 0 or 1) in the data.
                   11511:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11512:    * corresponding modality (h,j).
                   11513:    */
                   11514: 
1.145     brouard  11515:   h=0;
                   11516:   /*if (cptcovn > 0) */
1.126     brouard  11517:   m=pow(2,cptcoveff);
                   11518:  
1.144     brouard  11519:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11520:           * For k=4 covariates, h goes from 1 to m=2**k
                   11521:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11522:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11523:           *     h\k   1     2     3     4
1.143     brouard  11524:           *______________________________  
                   11525:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11526:           *     2     2     1     1     1
                   11527:           *     3 i=2 1     2     1     1
                   11528:           *     4     2     2     1     1
                   11529:           *     5 i=3 1 i=2 1     2     1
                   11530:           *     6     2     1     2     1
                   11531:           *     7 i=4 1     2     2     1
                   11532:           *     8     2     2     2     1
1.197     brouard  11533:           *     9 i=5 1 i=3 1 i=2 1     2
                   11534:           *    10     2     1     1     2
                   11535:           *    11 i=6 1     2     1     2
                   11536:           *    12     2     2     1     2
                   11537:           *    13 i=7 1 i=4 1     2     2    
                   11538:           *    14     2     1     2     2
                   11539:           *    15 i=8 1     2     2     2
                   11540:           *    16     2     2     2     2
1.143     brouard  11541:           */
1.212     brouard  11542:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11543:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11544:      * and the value of each covariate?
                   11545:      * V1=1, V2=1, V3=2, V4=1 ?
                   11546:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11547:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11548:      * In order to get the real value in the data, we use nbcode
                   11549:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11550:      * We are keeping this crazy system in order to be able (in the future?) 
                   11551:      * to have more than 2 values (0 or 1) for a covariate.
                   11552:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11553:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11554:      *              bbbbbbbb
                   11555:      *              76543210     
                   11556:      *   h-1        00000101 (6-1=5)
1.219     brouard  11557:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11558:      *           &
                   11559:      *     1        00000001 (1)
1.219     brouard  11560:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11561:      *          +1= 00000001 =1 
1.211     brouard  11562:      *
                   11563:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11564:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11565:      *    >>k'            11
                   11566:      *          &   00000001
                   11567:      *            = 00000001
                   11568:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11569:      * Reverse h=6 and m=16?
                   11570:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11571:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11572:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11573:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11574:      * V3=decodtabm(14,3,2**4)=2
                   11575:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11576:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11577:      *          &1 000000001
                   11578:      *           = 000000001
                   11579:      *         +1= 000000010 =2
                   11580:      *                  2211
                   11581:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11582:      *                  V3=2
1.220     brouard  11583:                 * codtabm and decodtabm are identical
1.211     brouard  11584:      */
                   11585: 
1.145     brouard  11586: 
                   11587:  free_ivector(Ndum,-1,NCOVMAX);
                   11588: 
                   11589: 
1.126     brouard  11590:     
1.186     brouard  11591:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11592:   strcpy(optionfilegnuplot,optionfilefiname);
                   11593:   if(mle==-3)
1.201     brouard  11594:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11595:   strcat(optionfilegnuplot,".gp");
                   11596: 
                   11597:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11598:     printf("Problem with file %s",optionfilegnuplot);
                   11599:   }
                   11600:   else{
1.204     brouard  11601:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11602:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11603:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11604:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11605:   }
                   11606:   /*  fclose(ficgp);*/
1.186     brouard  11607: 
                   11608: 
                   11609:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11610: 
                   11611:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11612:   if(mle==-3)
1.201     brouard  11613:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11614:   strcat(optionfilehtm,".htm");
                   11615:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11616:     printf("Problem with %s \n",optionfilehtm);
                   11617:     exit(0);
1.126     brouard  11618:   }
                   11619: 
                   11620:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11621:   strcat(optionfilehtmcov,"-cov.htm");
                   11622:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11623:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11624:   }
                   11625:   else{
                   11626:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11627: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11628: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11629:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11630:   }
                   11631: 
1.213     brouard  11632:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11633: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11634: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11635: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11636: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11637: \n\
                   11638: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11639:  <ul><li><h4>Parameter files</h4>\n\
                   11640:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11641:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11642:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11643:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11644:  - Date and time at start: %s</ul>\n",\
                   11645:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11646:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11647:          fileres,fileres,\
                   11648:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11649:   fflush(fichtm);
                   11650: 
                   11651:   strcpy(pathr,path);
                   11652:   strcat(pathr,optionfilefiname);
1.184     brouard  11653: #ifdef WIN32
                   11654:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11655: #else
1.126     brouard  11656:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11657: #endif
                   11658:          
1.126     brouard  11659:   
1.220     brouard  11660:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11661:                 and for any valid combination of covariates
1.126     brouard  11662:      and prints on file fileres'p'. */
1.251     brouard  11663:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11664:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11665: 
                   11666:   fprintf(fichtm,"\n");
1.286     brouard  11667:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11668:          ftol, stepm);
                   11669:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11670:   ncurrv=1;
                   11671:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11672:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11673:   ncurrv=i;
                   11674:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
                   11675:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) covariates: ntv=%d ", ntv);
                   11676:   ncurrv=i;
                   11677:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
                   11678:   fprintf(fichtm,"\n<li>Number of quantitative time varying covariates: nqtv=%d ", nqtv);
                   11679:   ncurrv=i;
                   11680:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11681:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11682:           nlstate, ndeath, maxwav, mle, weightopt);
                   11683: 
                   11684:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11685: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11686: 
                   11687:   
                   11688:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11689: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11690: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11691:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11692:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11693:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11694:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11695:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11696:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11697: 
1.126     brouard  11698:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11699:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11700:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11701: 
                   11702:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11703:   /* For mortality only */
1.126     brouard  11704:   if (mle==-3){
1.136     brouard  11705:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11706:     for(i=1;i<=NDIM;i++)
                   11707:       for(j=1;j<=NDIM;j++)
                   11708:        ximort[i][j]=0.;
1.186     brouard  11709:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11710:     cens=ivector(1,n);
                   11711:     ageexmed=vector(1,n);
                   11712:     agecens=vector(1,n);
                   11713:     dcwave=ivector(1,n);
1.223     brouard  11714:                
1.126     brouard  11715:     for (i=1; i<=imx; i++){
                   11716:       dcwave[i]=-1;
                   11717:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11718:        if (s[m][i]>nlstate) {
                   11719:          dcwave[i]=m;
                   11720:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11721:          break;
                   11722:        }
1.126     brouard  11723:     }
1.226     brouard  11724:     
1.126     brouard  11725:     for (i=1; i<=imx; i++) {
                   11726:       if (wav[i]>0){
1.226     brouard  11727:        ageexmed[i]=agev[mw[1][i]][i];
                   11728:        j=wav[i];
                   11729:        agecens[i]=1.; 
                   11730:        
                   11731:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11732:          agecens[i]=agev[mw[j][i]][i];
                   11733:          cens[i]= 1;
                   11734:        }else if (ageexmed[i]< 1) 
                   11735:          cens[i]= -1;
                   11736:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11737:          cens[i]=0 ;
1.126     brouard  11738:       }
                   11739:       else cens[i]=-1;
                   11740:     }
                   11741:     
                   11742:     for (i=1;i<=NDIM;i++) {
                   11743:       for (j=1;j<=NDIM;j++)
1.226     brouard  11744:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11745:     }
                   11746:     
1.145     brouard  11747:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11748:     /*printf("%lf %lf", p[1], p[2]);*/
                   11749:     
                   11750:     
1.136     brouard  11751: #ifdef GSL
                   11752:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11753: #else
1.126     brouard  11754:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11755: #endif
1.201     brouard  11756:     strcpy(filerespow,"POW-MORT_"); 
                   11757:     strcat(filerespow,fileresu);
1.126     brouard  11758:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11759:       printf("Problem with resultfile: %s\n", filerespow);
                   11760:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11761:     }
1.136     brouard  11762: #ifdef GSL
                   11763:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11764: #else
1.126     brouard  11765:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11766: #endif
1.126     brouard  11767:     /*  for (i=1;i<=nlstate;i++)
                   11768:        for(j=1;j<=nlstate+ndeath;j++)
                   11769:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11770:     */
                   11771:     fprintf(ficrespow,"\n");
1.136     brouard  11772: #ifdef GSL
                   11773:     /* gsl starts here */ 
                   11774:     T = gsl_multimin_fminimizer_nmsimplex;
                   11775:     gsl_multimin_fminimizer *sfm = NULL;
                   11776:     gsl_vector *ss, *x;
                   11777:     gsl_multimin_function minex_func;
                   11778: 
                   11779:     /* Initial vertex size vector */
                   11780:     ss = gsl_vector_alloc (NDIM);
                   11781:     
                   11782:     if (ss == NULL){
                   11783:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11784:     }
                   11785:     /* Set all step sizes to 1 */
                   11786:     gsl_vector_set_all (ss, 0.001);
                   11787: 
                   11788:     /* Starting point */
1.126     brouard  11789:     
1.136     brouard  11790:     x = gsl_vector_alloc (NDIM);
                   11791:     
                   11792:     if (x == NULL){
                   11793:       gsl_vector_free(ss);
                   11794:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11795:     }
                   11796:   
                   11797:     /* Initialize method and iterate */
                   11798:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11799:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11800:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11801:     gsl_vector_set(x, 0, p[1]);
                   11802:     gsl_vector_set(x, 1, p[2]);
                   11803: 
                   11804:     minex_func.f = &gompertz_f;
                   11805:     minex_func.n = NDIM;
                   11806:     minex_func.params = (void *)&p; /* ??? */
                   11807:     
                   11808:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11809:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11810:     
                   11811:     printf("Iterations beginning .....\n\n");
                   11812:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11813: 
                   11814:     iteri=0;
                   11815:     while (rval == GSL_CONTINUE){
                   11816:       iteri++;
                   11817:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11818:       
                   11819:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11820:       fflush(0);
                   11821:       
                   11822:       if (status) 
                   11823:         break;
                   11824:       
                   11825:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11826:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11827:       
                   11828:       if (rval == GSL_SUCCESS)
                   11829:         printf ("converged to a local maximum at\n");
                   11830:       
                   11831:       printf("%5d ", iteri);
                   11832:       for (it = 0; it < NDIM; it++){
                   11833:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11834:       }
                   11835:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11836:     }
                   11837:     
                   11838:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11839:     
                   11840:     gsl_vector_free(x); /* initial values */
                   11841:     gsl_vector_free(ss); /* inital step size */
                   11842:     for (it=0; it<NDIM; it++){
                   11843:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11844:       fprintf(ficrespow," %.12lf", p[it]);
                   11845:     }
                   11846:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11847: #endif
                   11848: #ifdef POWELL
                   11849:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11850: #endif  
1.126     brouard  11851:     fclose(ficrespow);
                   11852:     
1.203     brouard  11853:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11854: 
                   11855:     for(i=1; i <=NDIM; i++)
                   11856:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11857:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11858:     
                   11859:     printf("\nCovariance matrix\n ");
1.203     brouard  11860:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11861:     for(i=1; i <=NDIM; i++) {
                   11862:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11863:                                printf("%f ",matcov[i][j]);
                   11864:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11865:       }
1.203     brouard  11866:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11867:     }
                   11868:     
                   11869:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11870:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11871:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11872:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11873:     }
1.126     brouard  11874:     lsurv=vector(1,AGESUP);
                   11875:     lpop=vector(1,AGESUP);
                   11876:     tpop=vector(1,AGESUP);
                   11877:     lsurv[agegomp]=100000;
                   11878:     
                   11879:     for (k=agegomp;k<=AGESUP;k++) {
                   11880:       agemortsup=k;
                   11881:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11882:     }
                   11883:     
                   11884:     for (k=agegomp;k<agemortsup;k++)
                   11885:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11886:     
                   11887:     for (k=agegomp;k<agemortsup;k++){
                   11888:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11889:       sumlpop=sumlpop+lpop[k];
                   11890:     }
                   11891:     
                   11892:     tpop[agegomp]=sumlpop;
                   11893:     for (k=agegomp;k<(agemortsup-3);k++){
                   11894:       /*  tpop[k+1]=2;*/
                   11895:       tpop[k+1]=tpop[k]-lpop[k];
                   11896:     }
                   11897:     
                   11898:     
                   11899:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11900:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11901:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11902:     
                   11903:     
                   11904:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11905:                ageminpar=50;
                   11906:                agemaxpar=100;
1.194     brouard  11907:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11908:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11909: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11910: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11911:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11912: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11913: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11914:     }else{
                   11915:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11916:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11917:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11918:                }
1.201     brouard  11919:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11920:                     stepm, weightopt,\
                   11921:                     model,imx,p,matcov,agemortsup);
                   11922:     
                   11923:     free_vector(lsurv,1,AGESUP);
                   11924:     free_vector(lpop,1,AGESUP);
                   11925:     free_vector(tpop,1,AGESUP);
1.220     brouard  11926:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11927:     free_ivector(cens,1,n);
                   11928:     free_vector(agecens,1,n);
                   11929:     free_ivector(dcwave,1,n);
1.220     brouard  11930: #ifdef GSL
1.136     brouard  11931: #endif
1.186     brouard  11932:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11933:   /* Standard  */
                   11934:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11935:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11936:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11937:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11938:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11939:     for (k=1; k<=npar;k++)
                   11940:       printf(" %d %8.5f",k,p[k]);
                   11941:     printf("\n");
1.205     brouard  11942:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11943:       /* mlikeli uses func not funcone */
1.247     brouard  11944:       /* for(i=1;i<nlstate;i++){ */
                   11945:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11946:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11947:       /* } */
1.205     brouard  11948:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11949:     }
                   11950:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11951:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11952:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11953:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11954:     }
                   11955:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11956:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11957:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11958:     for (k=1; k<=npar;k++)
                   11959:       printf(" %d %8.5f",k,p[k]);
                   11960:     printf("\n");
                   11961:     
                   11962:     /*--------- results files --------------*/
1.283     brouard  11963:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  11964:     
                   11965:     
                   11966:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11967:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11968:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11969:     for(i=1,jk=1; i <=nlstate; i++){
                   11970:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11971:        if (k != i) {
                   11972:          printf("%d%d ",i,k);
                   11973:          fprintf(ficlog,"%d%d ",i,k);
                   11974:          fprintf(ficres,"%1d%1d ",i,k);
                   11975:          for(j=1; j <=ncovmodel; j++){
                   11976:            printf("%12.7f ",p[jk]);
                   11977:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11978:            fprintf(ficres,"%12.7f ",p[jk]);
                   11979:            jk++; 
                   11980:          }
                   11981:          printf("\n");
                   11982:          fprintf(ficlog,"\n");
                   11983:          fprintf(ficres,"\n");
                   11984:        }
1.126     brouard  11985:       }
                   11986:     }
1.203     brouard  11987:     if(mle != 0){
                   11988:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11989:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11990:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11991:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11992:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11993:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11994:        for(k=1; k <=(nlstate+ndeath); k++){
                   11995:          if (k != i) {
                   11996:            printf("%d%d ",i,k);
                   11997:            fprintf(ficlog,"%d%d ",i,k);
                   11998:            for(j=1; j <=ncovmodel; j++){
                   11999:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12000:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12001:              jk++; 
                   12002:            }
                   12003:            printf("\n");
                   12004:            fprintf(ficlog,"\n");
                   12005:          }
                   12006:        }
1.193     brouard  12007:       }
1.203     brouard  12008:     } /* end of hesscov and Wald tests */
1.225     brouard  12009:     
1.203     brouard  12010:     /*  */
1.126     brouard  12011:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12012:     printf("# Scales (for hessian or gradient estimation)\n");
                   12013:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12014:     for(i=1,jk=1; i <=nlstate; i++){
                   12015:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12016:        if (j!=i) {
                   12017:          fprintf(ficres,"%1d%1d",i,j);
                   12018:          printf("%1d%1d",i,j);
                   12019:          fprintf(ficlog,"%1d%1d",i,j);
                   12020:          for(k=1; k<=ncovmodel;k++){
                   12021:            printf(" %.5e",delti[jk]);
                   12022:            fprintf(ficlog," %.5e",delti[jk]);
                   12023:            fprintf(ficres," %.5e",delti[jk]);
                   12024:            jk++;
                   12025:          }
                   12026:          printf("\n");
                   12027:          fprintf(ficlog,"\n");
                   12028:          fprintf(ficres,"\n");
                   12029:        }
1.126     brouard  12030:       }
                   12031:     }
                   12032:     
                   12033:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12034:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12035:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12036:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12037:     /* # 121 Var(a12)\n\ */
                   12038:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12039:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12040:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12041:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12042:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12043:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12044:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12045:     
                   12046:     
                   12047:     /* Just to have a covariance matrix which will be more understandable
                   12048:        even is we still don't want to manage dictionary of variables
                   12049:     */
                   12050:     for(itimes=1;itimes<=2;itimes++){
                   12051:       jj=0;
                   12052:       for(i=1; i <=nlstate; i++){
1.225     brouard  12053:        for(j=1; j <=nlstate+ndeath; j++){
                   12054:          if(j==i) continue;
                   12055:          for(k=1; k<=ncovmodel;k++){
                   12056:            jj++;
                   12057:            ca[0]= k+'a'-1;ca[1]='\0';
                   12058:            if(itimes==1){
                   12059:              if(mle>=1)
                   12060:                printf("#%1d%1d%d",i,j,k);
                   12061:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12062:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12063:            }else{
                   12064:              if(mle>=1)
                   12065:                printf("%1d%1d%d",i,j,k);
                   12066:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12067:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12068:            }
                   12069:            ll=0;
                   12070:            for(li=1;li <=nlstate; li++){
                   12071:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12072:                if(lj==li) continue;
                   12073:                for(lk=1;lk<=ncovmodel;lk++){
                   12074:                  ll++;
                   12075:                  if(ll<=jj){
                   12076:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12077:                    if(ll<jj){
                   12078:                      if(itimes==1){
                   12079:                        if(mle>=1)
                   12080:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12081:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12082:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12083:                      }else{
                   12084:                        if(mle>=1)
                   12085:                          printf(" %.5e",matcov[jj][ll]); 
                   12086:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12087:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12088:                      }
                   12089:                    }else{
                   12090:                      if(itimes==1){
                   12091:                        if(mle>=1)
                   12092:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12093:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12094:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12095:                      }else{
                   12096:                        if(mle>=1)
                   12097:                          printf(" %.7e",matcov[jj][ll]); 
                   12098:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12099:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12100:                      }
                   12101:                    }
                   12102:                  }
                   12103:                } /* end lk */
                   12104:              } /* end lj */
                   12105:            } /* end li */
                   12106:            if(mle>=1)
                   12107:              printf("\n");
                   12108:            fprintf(ficlog,"\n");
                   12109:            fprintf(ficres,"\n");
                   12110:            numlinepar++;
                   12111:          } /* end k*/
                   12112:        } /*end j */
1.126     brouard  12113:       } /* end i */
                   12114:     } /* end itimes */
                   12115:     
                   12116:     fflush(ficlog);
                   12117:     fflush(ficres);
1.225     brouard  12118:     while(fgets(line, MAXLINE, ficpar)) {
                   12119:       /* If line starts with a # it is a comment */
                   12120:       if (line[0] == '#') {
                   12121:        numlinepar++;
                   12122:        fputs(line,stdout);
                   12123:        fputs(line,ficparo);
                   12124:        fputs(line,ficlog);
                   12125:        continue;
                   12126:       }else
                   12127:        break;
                   12128:     }
                   12129:     
1.209     brouard  12130:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12131:     /*   ungetc(c,ficpar); */
                   12132:     /*   fgets(line, MAXLINE, ficpar); */
                   12133:     /*   fputs(line,stdout); */
                   12134:     /*   fputs(line,ficparo); */
                   12135:     /* } */
                   12136:     /* ungetc(c,ficpar); */
1.126     brouard  12137:     
                   12138:     estepm=0;
1.209     brouard  12139:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12140:       
                   12141:       if (num_filled != 6) {
                   12142:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12143:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12144:        goto end;
                   12145:       }
                   12146:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12147:     }
                   12148:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12149:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12150:     
1.209     brouard  12151:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12152:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12153:     if (fage <= 2) {
                   12154:       bage = ageminpar;
                   12155:       fage = agemaxpar;
                   12156:     }
                   12157:     
                   12158:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12159:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12160:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12161:                
1.186     brouard  12162:     /* Other stuffs, more or less useful */    
1.254     brouard  12163:     while(fgets(line, MAXLINE, ficpar)) {
                   12164:       /* If line starts with a # it is a comment */
                   12165:       if (line[0] == '#') {
                   12166:        numlinepar++;
                   12167:        fputs(line,stdout);
                   12168:        fputs(line,ficparo);
                   12169:        fputs(line,ficlog);
                   12170:        continue;
                   12171:       }else
                   12172:        break;
                   12173:     }
                   12174: 
                   12175:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12176:       
                   12177:       if (num_filled != 7) {
                   12178:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12179:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12180:        goto end;
                   12181:       }
                   12182:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12183:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12184:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12185:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12186:     }
1.254     brouard  12187: 
                   12188:     while(fgets(line, MAXLINE, ficpar)) {
                   12189:       /* If line starts with a # it is a comment */
                   12190:       if (line[0] == '#') {
                   12191:        numlinepar++;
                   12192:        fputs(line,stdout);
                   12193:        fputs(line,ficparo);
                   12194:        fputs(line,ficlog);
                   12195:        continue;
                   12196:       }else
                   12197:        break;
1.126     brouard  12198:     }
                   12199:     
                   12200:     
                   12201:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12202:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12203:     
1.254     brouard  12204:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12205:       if (num_filled != 1) {
                   12206:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12207:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12208:        goto end;
                   12209:       }
                   12210:       printf("pop_based=%d\n",popbased);
                   12211:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12212:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12213:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12214:     }
                   12215:      
1.258     brouard  12216:     /* Results */
                   12217:     nresult=0;
                   12218:     do{
                   12219:       if(!fgets(line, MAXLINE, ficpar)){
                   12220:        endishere=1;
                   12221:        parameterline=14;
                   12222:       }else if (line[0] == '#') {
                   12223:        /* If line starts with a # it is a comment */
1.254     brouard  12224:        numlinepar++;
                   12225:        fputs(line,stdout);
                   12226:        fputs(line,ficparo);
                   12227:        fputs(line,ficlog);
                   12228:        continue;
1.258     brouard  12229:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12230:        parameterline=11;
                   12231:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12232:        parameterline=12;
                   12233:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12234:        parameterline=13;
                   12235:       else{
                   12236:        parameterline=14;
1.254     brouard  12237:       }
1.258     brouard  12238:       switch (parameterline){ 
                   12239:       case 11:
                   12240:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12241:          if (num_filled != 8) {
                   12242:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12243:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12244:            goto end;
                   12245:          }
                   12246:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12247:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12248:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12249:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12250:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12251:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12252:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12253: 
1.258     brouard  12254:        }
1.254     brouard  12255:        break;
1.258     brouard  12256:       case 12:
                   12257:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12258:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12259:          if (num_filled != 8) {
1.262     brouard  12260:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12261:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12262:            goto end;
                   12263:          }
                   12264:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12265:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12266:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12267:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12268:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12269:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12270:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12271:        }
1.230     brouard  12272:        break;
1.258     brouard  12273:       case 13:
                   12274:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12275:          if (num_filled == 0){
                   12276:            resultline[0]='\0';
                   12277:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12278:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12279:            break;
                   12280:          } else if (num_filled != 1){
                   12281:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12282:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12283:          }
                   12284:          nresult++; /* Sum of resultlines */
                   12285:          printf("Result %d: result=%s\n",nresult, resultline);
                   12286:          if(nresult > MAXRESULTLINES){
                   12287:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12288:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12289:            goto end;
                   12290:          }
                   12291:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12292:          fprintf(ficparo,"result: %s\n",resultline);
                   12293:          fprintf(ficres,"result: %s\n",resultline);
                   12294:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12295:          break;
1.258     brouard  12296:        case 14: 
1.259     brouard  12297:          if(ncovmodel >2 && nresult==0 ){
                   12298:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12299:            goto end;
                   12300:          }
1.259     brouard  12301:          break;
1.258     brouard  12302:        default:
                   12303:          nresult=1;
                   12304:          decoderesult(".",nresult ); /* No covariate */
                   12305:        }
                   12306:       } /* End switch parameterline */
                   12307:     }while(endishere==0); /* End do */
1.126     brouard  12308:     
1.230     brouard  12309:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12310:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12311:     
                   12312:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12313:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12314:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12315: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12316: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12317:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12318: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12319: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12320:     }else{
1.270     brouard  12321:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12322:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12323:     }
                   12324:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12325:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12326:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12327:                
1.225     brouard  12328:     /*------------ free_vector  -------------*/
                   12329:     /*  chdir(path); */
1.220     brouard  12330:                
1.215     brouard  12331:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12332:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12333:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12334:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12335:     free_lvector(num,1,n);
                   12336:     free_vector(agedc,1,n);
                   12337:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12338:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12339:     fclose(ficparo);
                   12340:     fclose(ficres);
1.220     brouard  12341:                
                   12342:                
1.186     brouard  12343:     /* Other results (useful)*/
1.220     brouard  12344:                
                   12345:                
1.126     brouard  12346:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12347:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12348:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12349:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12350:     fclose(ficrespl);
                   12351: 
                   12352:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12353:     /*#include "hpijx.h"*/
                   12354:     hPijx(p, bage, fage);
1.145     brouard  12355:     fclose(ficrespij);
1.227     brouard  12356:     
1.220     brouard  12357:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12358:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12359:     k=1;
1.126     brouard  12360:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12361:     
1.269     brouard  12362:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12363:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12364:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12365:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12366:        for(k=1;k<=ncovcombmax;k++)
                   12367:          probs[i][j][k]=0.;
1.269     brouard  12368:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12369:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12370:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12371:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12372:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12373:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12374:          for(k=1;k<=ncovcombmax;k++)
                   12375:            mobaverages[i][j][k]=0.;
1.219     brouard  12376:       mobaverage=mobaverages;
                   12377:       if (mobilav!=0) {
1.235     brouard  12378:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12379:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12380:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12381:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12382:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12383:        }
1.269     brouard  12384:       } else if (mobilavproj !=0) {
1.235     brouard  12385:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12386:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12387:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12388:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12389:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12390:        }
1.269     brouard  12391:       }else{
                   12392:        printf("Internal error moving average\n");
                   12393:        fflush(stdout);
                   12394:        exit(1);
1.219     brouard  12395:       }
                   12396:     }/* end if moving average */
1.227     brouard  12397:     
1.126     brouard  12398:     /*---------- Forecasting ------------------*/
                   12399:     if(prevfcast==1){
                   12400:       /*    if(stepm ==1){*/
1.269     brouard  12401:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12402:     }
1.269     brouard  12403: 
                   12404:     /* Backcasting */
1.217     brouard  12405:     if(backcast==1){
1.219     brouard  12406:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12407:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12408:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12409: 
                   12410:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12411: 
                   12412:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12413: 
1.219     brouard  12414:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12415:       fclose(ficresplb);
                   12416: 
1.222     brouard  12417:       hBijx(p, bage, fage, mobaverage);
                   12418:       fclose(ficrespijb);
1.219     brouard  12419: 
1.269     brouard  12420:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12421:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12422:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12423: 
                   12424:       
1.269     brouard  12425:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12426:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12427:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12428:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12429:     }    /* end  Backcasting */
1.268     brouard  12430:  
1.186     brouard  12431:  
                   12432:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12433: 
1.215     brouard  12434:     free_ivector(wav,1,imx);
                   12435:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12436:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12437:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12438:                
                   12439:                
1.127     brouard  12440:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12441:                
1.201     brouard  12442:     strcpy(filerese,"E_");
                   12443:     strcat(filerese,fileresu);
1.126     brouard  12444:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12445:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12446:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12447:     }
1.208     brouard  12448:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12449:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12450: 
                   12451:     pstamp(ficreseij);
1.219     brouard  12452:                
1.235     brouard  12453:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12454:     if (cptcovn < 1){i1=1;}
                   12455:     
                   12456:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12457:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12458:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12459:        continue;
1.219     brouard  12460:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12461:       printf("\n#****** ");
1.225     brouard  12462:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12463:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12464:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12465:       }
                   12466:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12467:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12468:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12469:       }
                   12470:       fprintf(ficreseij,"******\n");
1.235     brouard  12471:       printf("******\n");
1.219     brouard  12472:       
                   12473:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12474:       oldm=oldms;savm=savms;
1.235     brouard  12475:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12476:       
1.219     brouard  12477:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12478:     }
                   12479:     fclose(ficreseij);
1.208     brouard  12480:     printf("done evsij\n");fflush(stdout);
                   12481:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12482: 
1.218     brouard  12483:                
1.227     brouard  12484:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12485:                
1.201     brouard  12486:     strcpy(filerest,"T_");
                   12487:     strcat(filerest,fileresu);
1.127     brouard  12488:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12489:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12490:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12491:     }
1.208     brouard  12492:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12493:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12494:     strcpy(fileresstde,"STDE_");
                   12495:     strcat(fileresstde,fileresu);
1.126     brouard  12496:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12497:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12498:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12499:     }
1.227     brouard  12500:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12501:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12502: 
1.201     brouard  12503:     strcpy(filerescve,"CVE_");
                   12504:     strcat(filerescve,fileresu);
1.126     brouard  12505:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12506:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12507:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12508:     }
1.227     brouard  12509:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12510:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12511: 
1.201     brouard  12512:     strcpy(fileresv,"V_");
                   12513:     strcat(fileresv,fileresu);
1.126     brouard  12514:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12515:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12516:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12517:     }
1.227     brouard  12518:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12519:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12520: 
1.235     brouard  12521:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12522:     if (cptcovn < 1){i1=1;}
                   12523:     
                   12524:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12525:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12526:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12527:        continue;
1.242     brouard  12528:       printf("\n#****** Result for:");
                   12529:       fprintf(ficrest,"\n#****** Result for:");
                   12530:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12531:       for(j=1;j<=cptcoveff;j++){ 
                   12532:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12533:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12534:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12535:       }
1.235     brouard  12536:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12537:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12538:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12539:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12540:       }        
1.208     brouard  12541:       fprintf(ficrest,"******\n");
1.227     brouard  12542:       fprintf(ficlog,"******\n");
                   12543:       printf("******\n");
1.208     brouard  12544:       
                   12545:       fprintf(ficresstdeij,"\n#****** ");
                   12546:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12547:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12548:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12549:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12550:       }
1.235     brouard  12551:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12552:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12553:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12554:       }        
1.208     brouard  12555:       fprintf(ficresstdeij,"******\n");
                   12556:       fprintf(ficrescveij,"******\n");
                   12557:       
                   12558:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12559:       /* pstamp(ficresvij); */
1.225     brouard  12560:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12561:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12562:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12563:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12564:       }        
1.208     brouard  12565:       fprintf(ficresvij,"******\n");
                   12566:       
                   12567:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12568:       oldm=oldms;savm=savms;
1.235     brouard  12569:       printf(" cvevsij ");
                   12570:       fprintf(ficlog, " cvevsij ");
                   12571:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12572:       printf(" end cvevsij \n ");
                   12573:       fprintf(ficlog, " end cvevsij \n ");
                   12574:       
                   12575:       /*
                   12576:        */
                   12577:       /* goto endfree; */
                   12578:       
                   12579:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12580:       pstamp(ficrest);
                   12581:       
1.269     brouard  12582:       epj=vector(1,nlstate+1);
1.208     brouard  12583:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12584:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12585:        cptcod= 0; /* To be deleted */
                   12586:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12587:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12588:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12589:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12590:        if(vpopbased==1)
                   12591:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12592:        else
1.288   ! brouard  12593:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12594:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12595:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12596:        fprintf(ficrest,"\n");
                   12597:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288   ! brouard  12598:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
        !          12599:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12600:        for(age=bage; age <=fage ;age++){
1.235     brouard  12601:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12602:          if (vpopbased==1) {
                   12603:            if(mobilav ==0){
                   12604:              for(i=1; i<=nlstate;i++)
                   12605:                prlim[i][i]=probs[(int)age][i][k];
                   12606:            }else{ /* mobilav */ 
                   12607:              for(i=1; i<=nlstate;i++)
                   12608:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12609:            }
                   12610:          }
1.219     brouard  12611:          
1.227     brouard  12612:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12613:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12614:          /* printf(" age %4.0f ",age); */
                   12615:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12616:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12617:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12618:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12619:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12620:            }
                   12621:            epj[nlstate+1] +=epj[j];
                   12622:          }
                   12623:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12624:          
1.227     brouard  12625:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12626:            for(j=1;j <=nlstate;j++)
                   12627:              vepp += vareij[i][j][(int)age];
                   12628:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12629:          for(j=1;j <=nlstate;j++){
                   12630:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12631:          }
                   12632:          fprintf(ficrest,"\n");
                   12633:        }
1.208     brouard  12634:       } /* End vpopbased */
1.269     brouard  12635:       free_vector(epj,1,nlstate+1);
1.208     brouard  12636:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12637:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12638:       printf("done selection\n");fflush(stdout);
                   12639:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12640:       
1.235     brouard  12641:     } /* End k selection */
1.227     brouard  12642: 
                   12643:     printf("done State-specific expectancies\n");fflush(stdout);
                   12644:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12645: 
1.288   ! brouard  12646:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12647:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12648: 
1.227     brouard  12649:     
                   12650:     free_vector(weight,1,n);
                   12651:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12652:     free_imatrix(s,1,maxwav+1,1,n);
                   12653:     free_matrix(anint,1,maxwav,1,n); 
                   12654:     free_matrix(mint,1,maxwav,1,n);
                   12655:     free_ivector(cod,1,n);
                   12656:     free_ivector(tab,1,NCOVMAX);
                   12657:     fclose(ficresstdeij);
                   12658:     fclose(ficrescveij);
                   12659:     fclose(ficresvij);
                   12660:     fclose(ficrest);
                   12661:     fclose(ficpar);
                   12662:     
                   12663:     
1.126     brouard  12664:     /*---------- End : free ----------------*/
1.219     brouard  12665:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12666:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12667:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12668:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12669:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12670:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12671:   /* endfree:*/
                   12672:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12673:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12674:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12675:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12676:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12677:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12678:   free_matrix(covar,0,NCOVMAX,1,n);
                   12679:   free_matrix(matcov,1,npar,1,npar);
                   12680:   free_matrix(hess,1,npar,1,npar);
                   12681:   /*free_vector(delti,1,npar);*/
                   12682:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12683:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12684:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12685:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12686:   
                   12687:   free_ivector(ncodemax,1,NCOVMAX);
                   12688:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12689:   free_ivector(Dummy,-1,NCOVMAX);
                   12690:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12691:   free_ivector(DummyV,1,NCOVMAX);
                   12692:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12693:   free_ivector(Typevar,-1,NCOVMAX);
                   12694:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12695:   free_ivector(TvarsQ,1,NCOVMAX);
                   12696:   free_ivector(TvarsQind,1,NCOVMAX);
                   12697:   free_ivector(TvarsD,1,NCOVMAX);
                   12698:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12699:   free_ivector(TvarFD,1,NCOVMAX);
                   12700:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12701:   free_ivector(TvarF,1,NCOVMAX);
                   12702:   free_ivector(TvarFind,1,NCOVMAX);
                   12703:   free_ivector(TvarV,1,NCOVMAX);
                   12704:   free_ivector(TvarVind,1,NCOVMAX);
                   12705:   free_ivector(TvarA,1,NCOVMAX);
                   12706:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12707:   free_ivector(TvarFQ,1,NCOVMAX);
                   12708:   free_ivector(TvarFQind,1,NCOVMAX);
                   12709:   free_ivector(TvarVD,1,NCOVMAX);
                   12710:   free_ivector(TvarVDind,1,NCOVMAX);
                   12711:   free_ivector(TvarVQ,1,NCOVMAX);
                   12712:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12713:   free_ivector(Tvarsel,1,NCOVMAX);
                   12714:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12715:   free_ivector(Tposprod,1,NCOVMAX);
                   12716:   free_ivector(Tprod,1,NCOVMAX);
                   12717:   free_ivector(Tvaraff,1,NCOVMAX);
                   12718:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12719:   free_ivector(Tage,1,NCOVMAX);
                   12720:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12721:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12722:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12723:   
                   12724:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12725:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12726:   fflush(fichtm);
                   12727:   fflush(ficgp);
                   12728:   
1.227     brouard  12729:   
1.126     brouard  12730:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12731:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12732:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12733:   }else{
                   12734:     printf("End of Imach\n");
                   12735:     fprintf(ficlog,"End of Imach\n");
                   12736:   }
                   12737:   printf("See log file on %s\n",filelog);
                   12738:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12739:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12740:   rend_time = time(NULL);  
                   12741:   end_time = *localtime(&rend_time);
                   12742:   /* tml = *localtime(&end_time.tm_sec); */
                   12743:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12744:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12745:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12746:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12747:   
1.157     brouard  12748:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12749:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12750:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12751:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12752: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12753:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12754:   fclose(fichtm);
                   12755:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12756:   fclose(fichtmcov);
                   12757:   fclose(ficgp);
                   12758:   fclose(ficlog);
                   12759:   /*------ End -----------*/
1.227     brouard  12760:   
1.281     brouard  12761: 
                   12762: /* Executes gnuplot */
1.227     brouard  12763:   
                   12764:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12765: #ifdef WIN32
1.227     brouard  12766:   if (_chdir(pathcd) != 0)
                   12767:     printf("Can't move to directory %s!\n",path);
                   12768:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12769: #else
1.227     brouard  12770:     if(chdir(pathcd) != 0)
                   12771:       printf("Can't move to directory %s!\n", path);
                   12772:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12773: #endif 
1.126     brouard  12774:     printf("Current directory %s!\n",pathcd);
                   12775:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12776:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12777: #ifdef _WIN32
1.126     brouard  12778:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12779: #endif
                   12780:   if(!stat(plotcmd,&info)){
1.158     brouard  12781:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12782:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12783:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12784:     }else
                   12785:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12786: #ifdef __unix
1.126     brouard  12787:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12788:     if(!stat(plotcmd,&info)){
1.158     brouard  12789:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12790:     }else
                   12791:       strcpy(pplotcmd,plotcmd);
                   12792: #endif
                   12793:   }else
                   12794:     strcpy(pplotcmd,plotcmd);
                   12795:   
                   12796:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12797:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12798:   
1.126     brouard  12799:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12800:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12801:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12802:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12803:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12804:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12805:   }
1.158     brouard  12806:   printf(" Successful, please wait...");
1.126     brouard  12807:   while (z[0] != 'q') {
                   12808:     /* chdir(path); */
1.154     brouard  12809:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12810:     scanf("%s",z);
                   12811: /*     if (z[0] == 'c') system("./imach"); */
                   12812:     if (z[0] == 'e') {
1.158     brouard  12813: #ifdef __APPLE__
1.152     brouard  12814:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12815: #elif __linux
                   12816:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12817: #else
1.152     brouard  12818:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12819: #endif
                   12820:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12821:       system(pplotcmd);
1.126     brouard  12822:     }
                   12823:     else if (z[0] == 'g') system(plotcmd);
                   12824:     else if (z[0] == 'q') exit(0);
                   12825:   }
1.227     brouard  12826: end:
1.126     brouard  12827:   while (z[0] != 'q') {
1.195     brouard  12828:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12829:     scanf("%s",z);
                   12830:   }
1.283     brouard  12831:   printf("End\n");
1.282     brouard  12832:   exit(0);
1.126     brouard  12833: }

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