Annotation of imach/src/imach.c, revision 1.289

1.289   ! brouard     1: /* $Id: imach.c,v 1.288 2018/05/02 20:58:27 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.289   ! brouard     4:   Revision 1.288  2018/05/02 20:58:27  brouard
        !             5:   Summary: Some bugs fixed
        !             6: 
1.288     brouard     7:   Revision 1.287  2018/05/01 17:57:25  brouard
                      8:   Summary: Bug fixed by providing frequencies only for non missing covariates
                      9: 
1.287     brouard    10:   Revision 1.286  2018/04/27 14:27:04  brouard
                     11:   Summary: some minor bugs
                     12: 
1.286     brouard    13:   Revision 1.285  2018/04/21 21:02:16  brouard
                     14:   Summary: Some bugs fixed, valgrind tested
                     15: 
1.285     brouard    16:   Revision 1.284  2018/04/20 05:22:13  brouard
                     17:   Summary: Computing mean and stdeviation of fixed quantitative variables
                     18: 
1.284     brouard    19:   Revision 1.283  2018/04/19 14:49:16  brouard
                     20:   Summary: Some minor bugs fixed
                     21: 
1.283     brouard    22:   Revision 1.282  2018/02/27 22:50:02  brouard
                     23:   *** empty log message ***
                     24: 
1.282     brouard    25:   Revision 1.281  2018/02/27 19:25:23  brouard
                     26:   Summary: Adding second argument for quitting
                     27: 
1.281     brouard    28:   Revision 1.280  2018/02/21 07:58:13  brouard
                     29:   Summary: 0.99r15
                     30: 
                     31:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     32: 
1.280     brouard    33:   Revision 1.279  2017/07/20 13:35:01  brouard
                     34:   Summary: temporary working
                     35: 
1.279     brouard    36:   Revision 1.278  2017/07/19 14:09:02  brouard
                     37:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     38: 
1.278     brouard    39:   Revision 1.277  2017/07/17 08:53:49  brouard
                     40:   Summary: BOM files can be read now
                     41: 
1.277     brouard    42:   Revision 1.276  2017/06/30 15:48:31  brouard
                     43:   Summary: Graphs improvements
                     44: 
1.276     brouard    45:   Revision 1.275  2017/06/30 13:39:33  brouard
                     46:   Summary: Saito's color
                     47: 
1.275     brouard    48:   Revision 1.274  2017/06/29 09:47:08  brouard
                     49:   Summary: Version 0.99r14
                     50: 
1.274     brouard    51:   Revision 1.273  2017/06/27 11:06:02  brouard
                     52:   Summary: More documentation on projections
                     53: 
1.273     brouard    54:   Revision 1.272  2017/06/27 10:22:40  brouard
                     55:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     56: 
1.272     brouard    57:   Revision 1.271  2017/06/27 10:17:50  brouard
                     58:   Summary: Some bug with rint
                     59: 
1.271     brouard    60:   Revision 1.270  2017/05/24 05:45:29  brouard
                     61:   *** empty log message ***
                     62: 
1.270     brouard    63:   Revision 1.269  2017/05/23 08:39:25  brouard
                     64:   Summary: Code into subroutine, cleanings
                     65: 
1.269     brouard    66:   Revision 1.268  2017/05/18 20:09:32  brouard
                     67:   Summary: backprojection and confidence intervals of backprevalence
                     68: 
1.268     brouard    69:   Revision 1.267  2017/05/13 10:25:05  brouard
                     70:   Summary: temporary save for backprojection
                     71: 
1.267     brouard    72:   Revision 1.266  2017/05/13 07:26:12  brouard
                     73:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     74: 
1.266     brouard    75:   Revision 1.265  2017/04/26 16:22:11  brouard
                     76:   Summary: imach 0.99r13 Some bugs fixed
                     77: 
1.265     brouard    78:   Revision 1.264  2017/04/26 06:01:29  brouard
                     79:   Summary: Labels in graphs
                     80: 
1.264     brouard    81:   Revision 1.263  2017/04/24 15:23:15  brouard
                     82:   Summary: to save
                     83: 
1.263     brouard    84:   Revision 1.262  2017/04/18 16:48:12  brouard
                     85:   *** empty log message ***
                     86: 
1.262     brouard    87:   Revision 1.261  2017/04/05 10:14:09  brouard
                     88:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     89: 
1.261     brouard    90:   Revision 1.260  2017/04/04 17:46:59  brouard
                     91:   Summary: Gnuplot indexations fixed (humm)
                     92: 
1.260     brouard    93:   Revision 1.259  2017/04/04 13:01:16  brouard
                     94:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                     95: 
1.259     brouard    96:   Revision 1.258  2017/04/03 10:17:47  brouard
                     97:   Summary: Version 0.99r12
                     98: 
                     99:   Some cleanings, conformed with updated documentation.
                    100: 
1.258     brouard   101:   Revision 1.257  2017/03/29 16:53:30  brouard
                    102:   Summary: Temp
                    103: 
1.257     brouard   104:   Revision 1.256  2017/03/27 05:50:23  brouard
                    105:   Summary: Temporary
                    106: 
1.256     brouard   107:   Revision 1.255  2017/03/08 16:02:28  brouard
                    108:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    109: 
1.255     brouard   110:   Revision 1.254  2017/03/08 07:13:00  brouard
                    111:   Summary: Fixing data parameter line
                    112: 
1.254     brouard   113:   Revision 1.253  2016/12/15 11:59:41  brouard
                    114:   Summary: 0.99 in progress
                    115: 
1.253     brouard   116:   Revision 1.252  2016/09/15 21:15:37  brouard
                    117:   *** empty log message ***
                    118: 
1.252     brouard   119:   Revision 1.251  2016/09/15 15:01:13  brouard
                    120:   Summary: not working
                    121: 
1.251     brouard   122:   Revision 1.250  2016/09/08 16:07:27  brouard
                    123:   Summary: continue
                    124: 
1.250     brouard   125:   Revision 1.249  2016/09/07 17:14:18  brouard
                    126:   Summary: Starting values from frequencies
                    127: 
1.249     brouard   128:   Revision 1.248  2016/09/07 14:10:18  brouard
                    129:   *** empty log message ***
                    130: 
1.248     brouard   131:   Revision 1.247  2016/09/02 11:11:21  brouard
                    132:   *** empty log message ***
                    133: 
1.247     brouard   134:   Revision 1.246  2016/09/02 08:49:22  brouard
                    135:   *** empty log message ***
                    136: 
1.246     brouard   137:   Revision 1.245  2016/09/02 07:25:01  brouard
                    138:   *** empty log message ***
                    139: 
1.245     brouard   140:   Revision 1.244  2016/09/02 07:17:34  brouard
                    141:   *** empty log message ***
                    142: 
1.244     brouard   143:   Revision 1.243  2016/09/02 06:45:35  brouard
                    144:   *** empty log message ***
                    145: 
1.243     brouard   146:   Revision 1.242  2016/08/30 15:01:20  brouard
                    147:   Summary: Fixing a lots
                    148: 
1.242     brouard   149:   Revision 1.241  2016/08/29 17:17:25  brouard
                    150:   Summary: gnuplot problem in Back projection to fix
                    151: 
1.241     brouard   152:   Revision 1.240  2016/08/29 07:53:18  brouard
                    153:   Summary: Better
                    154: 
1.240     brouard   155:   Revision 1.239  2016/08/26 15:51:03  brouard
                    156:   Summary: Improvement in Powell output in order to copy and paste
                    157: 
                    158:   Author:
                    159: 
1.239     brouard   160:   Revision 1.238  2016/08/26 14:23:35  brouard
                    161:   Summary: Starting tests of 0.99
                    162: 
1.238     brouard   163:   Revision 1.237  2016/08/26 09:20:19  brouard
                    164:   Summary: to valgrind
                    165: 
1.237     brouard   166:   Revision 1.236  2016/08/25 10:50:18  brouard
                    167:   *** empty log message ***
                    168: 
1.236     brouard   169:   Revision 1.235  2016/08/25 06:59:23  brouard
                    170:   *** empty log message ***
                    171: 
1.235     brouard   172:   Revision 1.234  2016/08/23 16:51:20  brouard
                    173:   *** empty log message ***
                    174: 
1.234     brouard   175:   Revision 1.233  2016/08/23 07:40:50  brouard
                    176:   Summary: not working
                    177: 
1.233     brouard   178:   Revision 1.232  2016/08/22 14:20:21  brouard
                    179:   Summary: not working
                    180: 
1.232     brouard   181:   Revision 1.231  2016/08/22 07:17:15  brouard
                    182:   Summary: not working
                    183: 
1.231     brouard   184:   Revision 1.230  2016/08/22 06:55:53  brouard
                    185:   Summary: Not working
                    186: 
1.230     brouard   187:   Revision 1.229  2016/07/23 09:45:53  brouard
                    188:   Summary: Completing for func too
                    189: 
1.229     brouard   190:   Revision 1.228  2016/07/22 17:45:30  brouard
                    191:   Summary: Fixing some arrays, still debugging
                    192: 
1.227     brouard   193:   Revision 1.226  2016/07/12 18:42:34  brouard
                    194:   Summary: temp
                    195: 
1.226     brouard   196:   Revision 1.225  2016/07/12 08:40:03  brouard
                    197:   Summary: saving but not running
                    198: 
1.225     brouard   199:   Revision 1.224  2016/07/01 13:16:01  brouard
                    200:   Summary: Fixes
                    201: 
1.224     brouard   202:   Revision 1.223  2016/02/19 09:23:35  brouard
                    203:   Summary: temporary
                    204: 
1.223     brouard   205:   Revision 1.222  2016/02/17 08:14:50  brouard
                    206:   Summary: Probably last 0.98 stable version 0.98r6
                    207: 
1.222     brouard   208:   Revision 1.221  2016/02/15 23:35:36  brouard
                    209:   Summary: minor bug
                    210: 
1.220     brouard   211:   Revision 1.219  2016/02/15 00:48:12  brouard
                    212:   *** empty log message ***
                    213: 
1.219     brouard   214:   Revision 1.218  2016/02/12 11:29:23  brouard
                    215:   Summary: 0.99 Back projections
                    216: 
1.218     brouard   217:   Revision 1.217  2015/12/23 17:18:31  brouard
                    218:   Summary: Experimental backcast
                    219: 
1.217     brouard   220:   Revision 1.216  2015/12/18 17:32:11  brouard
                    221:   Summary: 0.98r4 Warning and status=-2
                    222: 
                    223:   Version 0.98r4 is now:
                    224:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    225:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    226:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    227: 
1.216     brouard   228:   Revision 1.215  2015/12/16 08:52:24  brouard
                    229:   Summary: 0.98r4 working
                    230: 
1.215     brouard   231:   Revision 1.214  2015/12/16 06:57:54  brouard
                    232:   Summary: temporary not working
                    233: 
1.214     brouard   234:   Revision 1.213  2015/12/11 18:22:17  brouard
                    235:   Summary: 0.98r4
                    236: 
1.213     brouard   237:   Revision 1.212  2015/11/21 12:47:24  brouard
                    238:   Summary: minor typo
                    239: 
1.212     brouard   240:   Revision 1.211  2015/11/21 12:41:11  brouard
                    241:   Summary: 0.98r3 with some graph of projected cross-sectional
                    242: 
                    243:   Author: Nicolas Brouard
                    244: 
1.211     brouard   245:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   246:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   247:   Summary: Adding ftolpl parameter
                    248:   Author: N Brouard
                    249: 
                    250:   We had difficulties to get smoothed confidence intervals. It was due
                    251:   to the period prevalence which wasn't computed accurately. The inner
                    252:   parameter ftolpl is now an outer parameter of the .imach parameter
                    253:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    254:   computation are long.
                    255: 
1.209     brouard   256:   Revision 1.208  2015/11/17 14:31:57  brouard
                    257:   Summary: temporary
                    258: 
1.208     brouard   259:   Revision 1.207  2015/10/27 17:36:57  brouard
                    260:   *** empty log message ***
                    261: 
1.207     brouard   262:   Revision 1.206  2015/10/24 07:14:11  brouard
                    263:   *** empty log message ***
                    264: 
1.206     brouard   265:   Revision 1.205  2015/10/23 15:50:53  brouard
                    266:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    267: 
1.205     brouard   268:   Revision 1.204  2015/10/01 16:20:26  brouard
                    269:   Summary: Some new graphs of contribution to likelihood
                    270: 
1.204     brouard   271:   Revision 1.203  2015/09/30 17:45:14  brouard
                    272:   Summary: looking at better estimation of the hessian
                    273: 
                    274:   Also a better criteria for convergence to the period prevalence And
                    275:   therefore adding the number of years needed to converge. (The
                    276:   prevalence in any alive state shold sum to one
                    277: 
1.203     brouard   278:   Revision 1.202  2015/09/22 19:45:16  brouard
                    279:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    280: 
1.202     brouard   281:   Revision 1.201  2015/09/15 17:34:58  brouard
                    282:   Summary: 0.98r0
                    283: 
                    284:   - Some new graphs like suvival functions
                    285:   - Some bugs fixed like model=1+age+V2.
                    286: 
1.201     brouard   287:   Revision 1.200  2015/09/09 16:53:55  brouard
                    288:   Summary: Big bug thanks to Flavia
                    289: 
                    290:   Even model=1+age+V2. did not work anymore
                    291: 
1.200     brouard   292:   Revision 1.199  2015/09/07 14:09:23  brouard
                    293:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    294: 
1.199     brouard   295:   Revision 1.198  2015/09/03 07:14:39  brouard
                    296:   Summary: 0.98q5 Flavia
                    297: 
1.198     brouard   298:   Revision 1.197  2015/09/01 18:24:39  brouard
                    299:   *** empty log message ***
                    300: 
1.197     brouard   301:   Revision 1.196  2015/08/18 23:17:52  brouard
                    302:   Summary: 0.98q5
                    303: 
1.196     brouard   304:   Revision 1.195  2015/08/18 16:28:39  brouard
                    305:   Summary: Adding a hack for testing purpose
                    306: 
                    307:   After reading the title, ftol and model lines, if the comment line has
                    308:   a q, starting with #q, the answer at the end of the run is quit. It
                    309:   permits to run test files in batch with ctest. The former workaround was
                    310:   $ echo q | imach foo.imach
                    311: 
1.195     brouard   312:   Revision 1.194  2015/08/18 13:32:00  brouard
                    313:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    314: 
1.194     brouard   315:   Revision 1.193  2015/08/04 07:17:42  brouard
                    316:   Summary: 0.98q4
                    317: 
1.193     brouard   318:   Revision 1.192  2015/07/16 16:49:02  brouard
                    319:   Summary: Fixing some outputs
                    320: 
1.192     brouard   321:   Revision 1.191  2015/07/14 10:00:33  brouard
                    322:   Summary: Some fixes
                    323: 
1.191     brouard   324:   Revision 1.190  2015/05/05 08:51:13  brouard
                    325:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    326: 
                    327:   Fix 1+age+.
                    328: 
1.190     brouard   329:   Revision 1.189  2015/04/30 14:45:16  brouard
                    330:   Summary: 0.98q2
                    331: 
1.189     brouard   332:   Revision 1.188  2015/04/30 08:27:53  brouard
                    333:   *** empty log message ***
                    334: 
1.188     brouard   335:   Revision 1.187  2015/04/29 09:11:15  brouard
                    336:   *** empty log message ***
                    337: 
1.187     brouard   338:   Revision 1.186  2015/04/23 12:01:52  brouard
                    339:   Summary: V1*age is working now, version 0.98q1
                    340: 
                    341:   Some codes had been disabled in order to simplify and Vn*age was
                    342:   working in the optimization phase, ie, giving correct MLE parameters,
                    343:   but, as usual, outputs were not correct and program core dumped.
                    344: 
1.186     brouard   345:   Revision 1.185  2015/03/11 13:26:42  brouard
                    346:   Summary: Inclusion of compile and links command line for Intel Compiler
                    347: 
1.185     brouard   348:   Revision 1.184  2015/03/11 11:52:39  brouard
                    349:   Summary: Back from Windows 8. Intel Compiler
                    350: 
1.184     brouard   351:   Revision 1.183  2015/03/10 20:34:32  brouard
                    352:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    353: 
                    354:   We use directest instead of original Powell test; probably no
                    355:   incidence on the results, but better justifications;
                    356:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    357:   wrong results.
                    358: 
1.183     brouard   359:   Revision 1.182  2015/02/12 08:19:57  brouard
                    360:   Summary: Trying to keep directest which seems simpler and more general
                    361:   Author: Nicolas Brouard
                    362: 
1.182     brouard   363:   Revision 1.181  2015/02/11 23:22:24  brouard
                    364:   Summary: Comments on Powell added
                    365: 
                    366:   Author:
                    367: 
1.181     brouard   368:   Revision 1.180  2015/02/11 17:33:45  brouard
                    369:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    370: 
1.180     brouard   371:   Revision 1.179  2015/01/04 09:57:06  brouard
                    372:   Summary: back to OS/X
                    373: 
1.179     brouard   374:   Revision 1.178  2015/01/04 09:35:48  brouard
                    375:   *** empty log message ***
                    376: 
1.178     brouard   377:   Revision 1.177  2015/01/03 18:40:56  brouard
                    378:   Summary: Still testing ilc32 on OSX
                    379: 
1.177     brouard   380:   Revision 1.176  2015/01/03 16:45:04  brouard
                    381:   *** empty log message ***
                    382: 
1.176     brouard   383:   Revision 1.175  2015/01/03 16:33:42  brouard
                    384:   *** empty log message ***
                    385: 
1.175     brouard   386:   Revision 1.174  2015/01/03 16:15:49  brouard
                    387:   Summary: Still in cross-compilation
                    388: 
1.174     brouard   389:   Revision 1.173  2015/01/03 12:06:26  brouard
                    390:   Summary: trying to detect cross-compilation
                    391: 
1.173     brouard   392:   Revision 1.172  2014/12/27 12:07:47  brouard
                    393:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    394: 
1.172     brouard   395:   Revision 1.171  2014/12/23 13:26:59  brouard
                    396:   Summary: Back from Visual C
                    397: 
                    398:   Still problem with utsname.h on Windows
                    399: 
1.171     brouard   400:   Revision 1.170  2014/12/23 11:17:12  brouard
                    401:   Summary: Cleaning some \%% back to %%
                    402: 
                    403:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    404: 
1.170     brouard   405:   Revision 1.169  2014/12/22 23:08:31  brouard
                    406:   Summary: 0.98p
                    407: 
                    408:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    409: 
1.169     brouard   410:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   411:   Summary: update
1.169     brouard   412: 
1.168     brouard   413:   Revision 1.167  2014/12/22 13:50:56  brouard
                    414:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    415: 
                    416:   Testing on Linux 64
                    417: 
1.167     brouard   418:   Revision 1.166  2014/12/22 11:40:47  brouard
                    419:   *** empty log message ***
                    420: 
1.166     brouard   421:   Revision 1.165  2014/12/16 11:20:36  brouard
                    422:   Summary: After compiling on Visual C
                    423: 
                    424:   * imach.c (Module): Merging 1.61 to 1.162
                    425: 
1.165     brouard   426:   Revision 1.164  2014/12/16 10:52:11  brouard
                    427:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    428: 
                    429:   * imach.c (Module): Merging 1.61 to 1.162
                    430: 
1.164     brouard   431:   Revision 1.163  2014/12/16 10:30:11  brouard
                    432:   * imach.c (Module): Merging 1.61 to 1.162
                    433: 
1.163     brouard   434:   Revision 1.162  2014/09/25 11:43:39  brouard
                    435:   Summary: temporary backup 0.99!
                    436: 
1.162     brouard   437:   Revision 1.1  2014/09/16 11:06:58  brouard
                    438:   Summary: With some code (wrong) for nlopt
                    439: 
                    440:   Author:
                    441: 
                    442:   Revision 1.161  2014/09/15 20:41:41  brouard
                    443:   Summary: Problem with macro SQR on Intel compiler
                    444: 
1.161     brouard   445:   Revision 1.160  2014/09/02 09:24:05  brouard
                    446:   *** empty log message ***
                    447: 
1.160     brouard   448:   Revision 1.159  2014/09/01 10:34:10  brouard
                    449:   Summary: WIN32
                    450:   Author: Brouard
                    451: 
1.159     brouard   452:   Revision 1.158  2014/08/27 17:11:51  brouard
                    453:   *** empty log message ***
                    454: 
1.158     brouard   455:   Revision 1.157  2014/08/27 16:26:55  brouard
                    456:   Summary: Preparing windows Visual studio version
                    457:   Author: Brouard
                    458: 
                    459:   In order to compile on Visual studio, time.h is now correct and time_t
                    460:   and tm struct should be used. difftime should be used but sometimes I
                    461:   just make the differences in raw time format (time(&now).
                    462:   Trying to suppress #ifdef LINUX
                    463:   Add xdg-open for __linux in order to open default browser.
                    464: 
1.157     brouard   465:   Revision 1.156  2014/08/25 20:10:10  brouard
                    466:   *** empty log message ***
                    467: 
1.156     brouard   468:   Revision 1.155  2014/08/25 18:32:34  brouard
                    469:   Summary: New compile, minor changes
                    470:   Author: Brouard
                    471: 
1.155     brouard   472:   Revision 1.154  2014/06/20 17:32:08  brouard
                    473:   Summary: Outputs now all graphs of convergence to period prevalence
                    474: 
1.154     brouard   475:   Revision 1.153  2014/06/20 16:45:46  brouard
                    476:   Summary: If 3 live state, convergence to period prevalence on same graph
                    477:   Author: Brouard
                    478: 
1.153     brouard   479:   Revision 1.152  2014/06/18 17:54:09  brouard
                    480:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    481: 
1.152     brouard   482:   Revision 1.151  2014/06/18 16:43:30  brouard
                    483:   *** empty log message ***
                    484: 
1.151     brouard   485:   Revision 1.150  2014/06/18 16:42:35  brouard
                    486:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    487:   Author: brouard
                    488: 
1.150     brouard   489:   Revision 1.149  2014/06/18 15:51:14  brouard
                    490:   Summary: Some fixes in parameter files errors
                    491:   Author: Nicolas Brouard
                    492: 
1.149     brouard   493:   Revision 1.148  2014/06/17 17:38:48  brouard
                    494:   Summary: Nothing new
                    495:   Author: Brouard
                    496: 
                    497:   Just a new packaging for OS/X version 0.98nS
                    498: 
1.148     brouard   499:   Revision 1.147  2014/06/16 10:33:11  brouard
                    500:   *** empty log message ***
                    501: 
1.147     brouard   502:   Revision 1.146  2014/06/16 10:20:28  brouard
                    503:   Summary: Merge
                    504:   Author: Brouard
                    505: 
                    506:   Merge, before building revised version.
                    507: 
1.146     brouard   508:   Revision 1.145  2014/06/10 21:23:15  brouard
                    509:   Summary: Debugging with valgrind
                    510:   Author: Nicolas Brouard
                    511: 
                    512:   Lot of changes in order to output the results with some covariates
                    513:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    514:   improve the code.
                    515:   No more memory valgrind error but a lot has to be done in order to
                    516:   continue the work of splitting the code into subroutines.
                    517:   Also, decodemodel has been improved. Tricode is still not
                    518:   optimal. nbcode should be improved. Documentation has been added in
                    519:   the source code.
                    520: 
1.144     brouard   521:   Revision 1.143  2014/01/26 09:45:38  brouard
                    522:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    523: 
                    524:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    525:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    526: 
1.143     brouard   527:   Revision 1.142  2014/01/26 03:57:36  brouard
                    528:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    529: 
                    530:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    531: 
1.142     brouard   532:   Revision 1.141  2014/01/26 02:42:01  brouard
                    533:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    534: 
1.141     brouard   535:   Revision 1.140  2011/09/02 10:37:54  brouard
                    536:   Summary: times.h is ok with mingw32 now.
                    537: 
1.140     brouard   538:   Revision 1.139  2010/06/14 07:50:17  brouard
                    539:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    540:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    541: 
1.139     brouard   542:   Revision 1.138  2010/04/30 18:19:40  brouard
                    543:   *** empty log message ***
                    544: 
1.138     brouard   545:   Revision 1.137  2010/04/29 18:11:38  brouard
                    546:   (Module): Checking covariates for more complex models
                    547:   than V1+V2. A lot of change to be done. Unstable.
                    548: 
1.137     brouard   549:   Revision 1.136  2010/04/26 20:30:53  brouard
                    550:   (Module): merging some libgsl code. Fixing computation
                    551:   of likelione (using inter/intrapolation if mle = 0) in order to
                    552:   get same likelihood as if mle=1.
                    553:   Some cleaning of code and comments added.
                    554: 
1.136     brouard   555:   Revision 1.135  2009/10/29 15:33:14  brouard
                    556:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    557: 
1.135     brouard   558:   Revision 1.134  2009/10/29 13:18:53  brouard
                    559:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    560: 
1.134     brouard   561:   Revision 1.133  2009/07/06 10:21:25  brouard
                    562:   just nforces
                    563: 
1.133     brouard   564:   Revision 1.132  2009/07/06 08:22:05  brouard
                    565:   Many tings
                    566: 
1.132     brouard   567:   Revision 1.131  2009/06/20 16:22:47  brouard
                    568:   Some dimensions resccaled
                    569: 
1.131     brouard   570:   Revision 1.130  2009/05/26 06:44:34  brouard
                    571:   (Module): Max Covariate is now set to 20 instead of 8. A
                    572:   lot of cleaning with variables initialized to 0. Trying to make
                    573:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    574: 
1.130     brouard   575:   Revision 1.129  2007/08/31 13:49:27  lievre
                    576:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    577: 
1.129     lievre    578:   Revision 1.128  2006/06/30 13:02:05  brouard
                    579:   (Module): Clarifications on computing e.j
                    580: 
1.128     brouard   581:   Revision 1.127  2006/04/28 18:11:50  brouard
                    582:   (Module): Yes the sum of survivors was wrong since
                    583:   imach-114 because nhstepm was no more computed in the age
                    584:   loop. Now we define nhstepma in the age loop.
                    585:   (Module): In order to speed up (in case of numerous covariates) we
                    586:   compute health expectancies (without variances) in a first step
                    587:   and then all the health expectancies with variances or standard
                    588:   deviation (needs data from the Hessian matrices) which slows the
                    589:   computation.
                    590:   In the future we should be able to stop the program is only health
                    591:   expectancies and graph are needed without standard deviations.
                    592: 
1.127     brouard   593:   Revision 1.126  2006/04/28 17:23:28  brouard
                    594:   (Module): Yes the sum of survivors was wrong since
                    595:   imach-114 because nhstepm was no more computed in the age
                    596:   loop. Now we define nhstepma in the age loop.
                    597:   Version 0.98h
                    598: 
1.126     brouard   599:   Revision 1.125  2006/04/04 15:20:31  lievre
                    600:   Errors in calculation of health expectancies. Age was not initialized.
                    601:   Forecasting file added.
                    602: 
                    603:   Revision 1.124  2006/03/22 17:13:53  lievre
                    604:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    605:   The log-likelihood is printed in the log file
                    606: 
                    607:   Revision 1.123  2006/03/20 10:52:43  brouard
                    608:   * imach.c (Module): <title> changed, corresponds to .htm file
                    609:   name. <head> headers where missing.
                    610: 
                    611:   * imach.c (Module): Weights can have a decimal point as for
                    612:   English (a comma might work with a correct LC_NUMERIC environment,
                    613:   otherwise the weight is truncated).
                    614:   Modification of warning when the covariates values are not 0 or
                    615:   1.
                    616:   Version 0.98g
                    617: 
                    618:   Revision 1.122  2006/03/20 09:45:41  brouard
                    619:   (Module): Weights can have a decimal point as for
                    620:   English (a comma might work with a correct LC_NUMERIC environment,
                    621:   otherwise the weight is truncated).
                    622:   Modification of warning when the covariates values are not 0 or
                    623:   1.
                    624:   Version 0.98g
                    625: 
                    626:   Revision 1.121  2006/03/16 17:45:01  lievre
                    627:   * imach.c (Module): Comments concerning covariates added
                    628: 
                    629:   * imach.c (Module): refinements in the computation of lli if
                    630:   status=-2 in order to have more reliable computation if stepm is
                    631:   not 1 month. Version 0.98f
                    632: 
                    633:   Revision 1.120  2006/03/16 15:10:38  lievre
                    634:   (Module): refinements in the computation of lli if
                    635:   status=-2 in order to have more reliable computation if stepm is
                    636:   not 1 month. Version 0.98f
                    637: 
                    638:   Revision 1.119  2006/03/15 17:42:26  brouard
                    639:   (Module): Bug if status = -2, the loglikelihood was
                    640:   computed as likelihood omitting the logarithm. Version O.98e
                    641: 
                    642:   Revision 1.118  2006/03/14 18:20:07  brouard
                    643:   (Module): varevsij Comments added explaining the second
                    644:   table of variances if popbased=1 .
                    645:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    646:   (Module): Function pstamp added
                    647:   (Module): Version 0.98d
                    648: 
                    649:   Revision 1.117  2006/03/14 17:16:22  brouard
                    650:   (Module): varevsij Comments added explaining the second
                    651:   table of variances if popbased=1 .
                    652:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    653:   (Module): Function pstamp added
                    654:   (Module): Version 0.98d
                    655: 
                    656:   Revision 1.116  2006/03/06 10:29:27  brouard
                    657:   (Module): Variance-covariance wrong links and
                    658:   varian-covariance of ej. is needed (Saito).
                    659: 
                    660:   Revision 1.115  2006/02/27 12:17:45  brouard
                    661:   (Module): One freematrix added in mlikeli! 0.98c
                    662: 
                    663:   Revision 1.114  2006/02/26 12:57:58  brouard
                    664:   (Module): Some improvements in processing parameter
                    665:   filename with strsep.
                    666: 
                    667:   Revision 1.113  2006/02/24 14:20:24  brouard
                    668:   (Module): Memory leaks checks with valgrind and:
                    669:   datafile was not closed, some imatrix were not freed and on matrix
                    670:   allocation too.
                    671: 
                    672:   Revision 1.112  2006/01/30 09:55:26  brouard
                    673:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    674: 
                    675:   Revision 1.111  2006/01/25 20:38:18  brouard
                    676:   (Module): Lots of cleaning and bugs added (Gompertz)
                    677:   (Module): Comments can be added in data file. Missing date values
                    678:   can be a simple dot '.'.
                    679: 
                    680:   Revision 1.110  2006/01/25 00:51:50  brouard
                    681:   (Module): Lots of cleaning and bugs added (Gompertz)
                    682: 
                    683:   Revision 1.109  2006/01/24 19:37:15  brouard
                    684:   (Module): Comments (lines starting with a #) are allowed in data.
                    685: 
                    686:   Revision 1.108  2006/01/19 18:05:42  lievre
                    687:   Gnuplot problem appeared...
                    688:   To be fixed
                    689: 
                    690:   Revision 1.107  2006/01/19 16:20:37  brouard
                    691:   Test existence of gnuplot in imach path
                    692: 
                    693:   Revision 1.106  2006/01/19 13:24:36  brouard
                    694:   Some cleaning and links added in html output
                    695: 
                    696:   Revision 1.105  2006/01/05 20:23:19  lievre
                    697:   *** empty log message ***
                    698: 
                    699:   Revision 1.104  2005/09/30 16:11:43  lievre
                    700:   (Module): sump fixed, loop imx fixed, and simplifications.
                    701:   (Module): If the status is missing at the last wave but we know
                    702:   that the person is alive, then we can code his/her status as -2
                    703:   (instead of missing=-1 in earlier versions) and his/her
                    704:   contributions to the likelihood is 1 - Prob of dying from last
                    705:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    706:   the healthy state at last known wave). Version is 0.98
                    707: 
                    708:   Revision 1.103  2005/09/30 15:54:49  lievre
                    709:   (Module): sump fixed, loop imx fixed, and simplifications.
                    710: 
                    711:   Revision 1.102  2004/09/15 17:31:30  brouard
                    712:   Add the possibility to read data file including tab characters.
                    713: 
                    714:   Revision 1.101  2004/09/15 10:38:38  brouard
                    715:   Fix on curr_time
                    716: 
                    717:   Revision 1.100  2004/07/12 18:29:06  brouard
                    718:   Add version for Mac OS X. Just define UNIX in Makefile
                    719: 
                    720:   Revision 1.99  2004/06/05 08:57:40  brouard
                    721:   *** empty log message ***
                    722: 
                    723:   Revision 1.98  2004/05/16 15:05:56  brouard
                    724:   New version 0.97 . First attempt to estimate force of mortality
                    725:   directly from the data i.e. without the need of knowing the health
                    726:   state at each age, but using a Gompertz model: log u =a + b*age .
                    727:   This is the basic analysis of mortality and should be done before any
                    728:   other analysis, in order to test if the mortality estimated from the
                    729:   cross-longitudinal survey is different from the mortality estimated
                    730:   from other sources like vital statistic data.
                    731: 
                    732:   The same imach parameter file can be used but the option for mle should be -3.
                    733: 
1.133     brouard   734:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   735:   former routines in order to include the new code within the former code.
                    736: 
                    737:   The output is very simple: only an estimate of the intercept and of
                    738:   the slope with 95% confident intervals.
                    739: 
                    740:   Current limitations:
                    741:   A) Even if you enter covariates, i.e. with the
                    742:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    743:   B) There is no computation of Life Expectancy nor Life Table.
                    744: 
                    745:   Revision 1.97  2004/02/20 13:25:42  lievre
                    746:   Version 0.96d. Population forecasting command line is (temporarily)
                    747:   suppressed.
                    748: 
                    749:   Revision 1.96  2003/07/15 15:38:55  brouard
                    750:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    751:   rewritten within the same printf. Workaround: many printfs.
                    752: 
                    753:   Revision 1.95  2003/07/08 07:54:34  brouard
                    754:   * imach.c (Repository):
                    755:   (Repository): Using imachwizard code to output a more meaningful covariance
                    756:   matrix (cov(a12,c31) instead of numbers.
                    757: 
                    758:   Revision 1.94  2003/06/27 13:00:02  brouard
                    759:   Just cleaning
                    760: 
                    761:   Revision 1.93  2003/06/25 16:33:55  brouard
                    762:   (Module): On windows (cygwin) function asctime_r doesn't
                    763:   exist so I changed back to asctime which exists.
                    764:   (Module): Version 0.96b
                    765: 
                    766:   Revision 1.92  2003/06/25 16:30:45  brouard
                    767:   (Module): On windows (cygwin) function asctime_r doesn't
                    768:   exist so I changed back to asctime which exists.
                    769: 
                    770:   Revision 1.91  2003/06/25 15:30:29  brouard
                    771:   * imach.c (Repository): Duplicated warning errors corrected.
                    772:   (Repository): Elapsed time after each iteration is now output. It
                    773:   helps to forecast when convergence will be reached. Elapsed time
                    774:   is stamped in powell.  We created a new html file for the graphs
                    775:   concerning matrix of covariance. It has extension -cov.htm.
                    776: 
                    777:   Revision 1.90  2003/06/24 12:34:15  brouard
                    778:   (Module): Some bugs corrected for windows. Also, when
                    779:   mle=-1 a template is output in file "or"mypar.txt with the design
                    780:   of the covariance matrix to be input.
                    781: 
                    782:   Revision 1.89  2003/06/24 12:30:52  brouard
                    783:   (Module): Some bugs corrected for windows. Also, when
                    784:   mle=-1 a template is output in file "or"mypar.txt with the design
                    785:   of the covariance matrix to be input.
                    786: 
                    787:   Revision 1.88  2003/06/23 17:54:56  brouard
                    788:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    789: 
                    790:   Revision 1.87  2003/06/18 12:26:01  brouard
                    791:   Version 0.96
                    792: 
                    793:   Revision 1.86  2003/06/17 20:04:08  brouard
                    794:   (Module): Change position of html and gnuplot routines and added
                    795:   routine fileappend.
                    796: 
                    797:   Revision 1.85  2003/06/17 13:12:43  brouard
                    798:   * imach.c (Repository): Check when date of death was earlier that
                    799:   current date of interview. It may happen when the death was just
                    800:   prior to the death. In this case, dh was negative and likelihood
                    801:   was wrong (infinity). We still send an "Error" but patch by
                    802:   assuming that the date of death was just one stepm after the
                    803:   interview.
                    804:   (Repository): Because some people have very long ID (first column)
                    805:   we changed int to long in num[] and we added a new lvector for
                    806:   memory allocation. But we also truncated to 8 characters (left
                    807:   truncation)
                    808:   (Repository): No more line truncation errors.
                    809: 
                    810:   Revision 1.84  2003/06/13 21:44:43  brouard
                    811:   * imach.c (Repository): Replace "freqsummary" at a correct
                    812:   place. It differs from routine "prevalence" which may be called
                    813:   many times. Probs is memory consuming and must be used with
                    814:   parcimony.
                    815:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    816: 
                    817:   Revision 1.83  2003/06/10 13:39:11  lievre
                    818:   *** empty log message ***
                    819: 
                    820:   Revision 1.82  2003/06/05 15:57:20  brouard
                    821:   Add log in  imach.c and  fullversion number is now printed.
                    822: 
                    823: */
                    824: /*
                    825:    Interpolated Markov Chain
                    826: 
                    827:   Short summary of the programme:
                    828:   
1.227     brouard   829:   This program computes Healthy Life Expectancies or State-specific
                    830:   (if states aren't health statuses) Expectancies from
                    831:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    832: 
                    833:   -1- a first survey ("cross") where individuals from different ages
                    834:   are interviewed on their health status or degree of disability (in
                    835:   the case of a health survey which is our main interest)
                    836: 
                    837:   -2- at least a second wave of interviews ("longitudinal") which
                    838:   measure each change (if any) in individual health status.  Health
                    839:   expectancies are computed from the time spent in each health state
                    840:   according to a model. More health states you consider, more time is
                    841:   necessary to reach the Maximum Likelihood of the parameters involved
                    842:   in the model.  The simplest model is the multinomial logistic model
                    843:   where pij is the probability to be observed in state j at the second
                    844:   wave conditional to be observed in state i at the first
                    845:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    846:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    847:   have a more complex model than "constant and age", you should modify
                    848:   the program where the markup *Covariates have to be included here
                    849:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   850:   convergence.
                    851: 
                    852:   The advantage of this computer programme, compared to a simple
                    853:   multinomial logistic model, is clear when the delay between waves is not
                    854:   identical for each individual. Also, if a individual missed an
                    855:   intermediate interview, the information is lost, but taken into
                    856:   account using an interpolation or extrapolation.  
                    857: 
                    858:   hPijx is the probability to be observed in state i at age x+h
                    859:   conditional to the observed state i at age x. The delay 'h' can be
                    860:   split into an exact number (nh*stepm) of unobserved intermediate
                    861:   states. This elementary transition (by month, quarter,
                    862:   semester or year) is modelled as a multinomial logistic.  The hPx
                    863:   matrix is simply the matrix product of nh*stepm elementary matrices
                    864:   and the contribution of each individual to the likelihood is simply
                    865:   hPijx.
                    866: 
                    867:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   868:   of the life expectancies. It also computes the period (stable) prevalence.
                    869: 
                    870: Back prevalence and projections:
1.227     brouard   871: 
                    872:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    873:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    874:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    875:    mobilavproj)
                    876: 
                    877:     Computes the back prevalence limit for any combination of
                    878:     covariate values k at any age between ageminpar and agemaxpar and
                    879:     returns it in **bprlim. In the loops,
                    880: 
                    881:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    882:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    883: 
                    884:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   885:    Computes for any combination of covariates k and any age between bage and fage 
                    886:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    887:                        oldm=oldms;savm=savms;
1.227     brouard   888: 
1.267     brouard   889:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   890:      Computes the transition matrix starting at age 'age' over
                    891:      'nhstepm*hstepm*stepm' months (i.e. until
                    892:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   893:      nhstepm*hstepm matrices. 
                    894: 
                    895:      Returns p3mat[i][j][h] after calling
                    896:      p3mat[i][j][h]=matprod2(newm,
                    897:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    898:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    899:      oldm);
1.226     brouard   900: 
                    901: Important routines
                    902: 
                    903: - func (or funcone), computes logit (pij) distinguishing
                    904:   o fixed variables (single or product dummies or quantitative);
                    905:   o varying variables by:
                    906:    (1) wave (single, product dummies, quantitative), 
                    907:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    908:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    909:        % varying dummy (not done) or quantitative (not done);
                    910: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    911:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    912: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    913:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    914:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   915: 
1.226     brouard   916: 
                    917:   
1.133     brouard   918:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    919:            Institut national d'études démographiques, Paris.
1.126     brouard   920:   This software have been partly granted by Euro-REVES, a concerted action
                    921:   from the European Union.
                    922:   It is copyrighted identically to a GNU software product, ie programme and
                    923:   software can be distributed freely for non commercial use. Latest version
                    924:   can be accessed at http://euroreves.ined.fr/imach .
                    925: 
                    926:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    927:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    928:   
                    929:   **********************************************************************/
                    930: /*
                    931:   main
                    932:   read parameterfile
                    933:   read datafile
                    934:   concatwav
                    935:   freqsummary
                    936:   if (mle >= 1)
                    937:     mlikeli
                    938:   print results files
                    939:   if mle==1 
                    940:      computes hessian
                    941:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    942:       begin-prev-date,...
                    943:   open gnuplot file
                    944:   open html file
1.145     brouard   945:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    946:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    947:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    948:     freexexit2 possible for memory heap.
                    949: 
                    950:   h Pij x                         | pij_nom  ficrestpij
                    951:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    952:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    953:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    954: 
                    955:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    956:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    957:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    958:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    959:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    960: 
1.126     brouard   961:   forecasting if prevfcast==1 prevforecast call prevalence()
                    962:   health expectancies
                    963:   Variance-covariance of DFLE
                    964:   prevalence()
                    965:    movingaverage()
                    966:   varevsij() 
                    967:   if popbased==1 varevsij(,popbased)
                    968:   total life expectancies
                    969:   Variance of period (stable) prevalence
                    970:  end
                    971: */
                    972: 
1.187     brouard   973: /* #define DEBUG */
                    974: /* #define DEBUGBRENT */
1.203     brouard   975: /* #define DEBUGLINMIN */
                    976: /* #define DEBUGHESS */
                    977: #define DEBUGHESSIJ
1.224     brouard   978: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   979: #define POWELL /* Instead of NLOPT */
1.224     brouard   980: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   981: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    982: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   983: 
                    984: #include <math.h>
                    985: #include <stdio.h>
                    986: #include <stdlib.h>
                    987: #include <string.h>
1.226     brouard   988: #include <ctype.h>
1.159     brouard   989: 
                    990: #ifdef _WIN32
                    991: #include <io.h>
1.172     brouard   992: #include <windows.h>
                    993: #include <tchar.h>
1.159     brouard   994: #else
1.126     brouard   995: #include <unistd.h>
1.159     brouard   996: #endif
1.126     brouard   997: 
                    998: #include <limits.h>
                    999: #include <sys/types.h>
1.171     brouard  1000: 
                   1001: #if defined(__GNUC__)
                   1002: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1003: #endif
                   1004: 
1.126     brouard  1005: #include <sys/stat.h>
                   1006: #include <errno.h>
1.159     brouard  1007: /* extern int errno; */
1.126     brouard  1008: 
1.157     brouard  1009: /* #ifdef LINUX */
                   1010: /* #include <time.h> */
                   1011: /* #include "timeval.h" */
                   1012: /* #else */
                   1013: /* #include <sys/time.h> */
                   1014: /* #endif */
                   1015: 
1.126     brouard  1016: #include <time.h>
                   1017: 
1.136     brouard  1018: #ifdef GSL
                   1019: #include <gsl/gsl_errno.h>
                   1020: #include <gsl/gsl_multimin.h>
                   1021: #endif
                   1022: 
1.167     brouard  1023: 
1.162     brouard  1024: #ifdef NLOPT
                   1025: #include <nlopt.h>
                   1026: typedef struct {
                   1027:   double (* function)(double [] );
                   1028: } myfunc_data ;
                   1029: #endif
                   1030: 
1.126     brouard  1031: /* #include <libintl.h> */
                   1032: /* #define _(String) gettext (String) */
                   1033: 
1.251     brouard  1034: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1035: 
                   1036: #define GNUPLOTPROGRAM "gnuplot"
                   1037: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1038: #define FILENAMELENGTH 132
                   1039: 
                   1040: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1041: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1042: 
1.144     brouard  1043: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1044: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1045: 
                   1046: #define NINTERVMAX 8
1.144     brouard  1047: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1048: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
                   1049: #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1050: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1051: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1052: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.126     brouard  1053: #define MAXN 20000
1.144     brouard  1054: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1055: /* #define AGESUP 130 */
1.288     brouard  1056: /* #define AGESUP 150 */
                   1057: #define AGESUP 200
1.268     brouard  1058: #define AGEINF 0
1.218     brouard  1059: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1060: #define AGEBASE 40
1.194     brouard  1061: #define AGEOVERFLOW 1.e20
1.164     brouard  1062: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1063: #ifdef _WIN32
                   1064: #define DIRSEPARATOR '\\'
                   1065: #define CHARSEPARATOR "\\"
                   1066: #define ODIRSEPARATOR '/'
                   1067: #else
1.126     brouard  1068: #define DIRSEPARATOR '/'
                   1069: #define CHARSEPARATOR "/"
                   1070: #define ODIRSEPARATOR '\\'
                   1071: #endif
                   1072: 
1.289   ! brouard  1073: /* $Id: imach.c,v 1.288 2018/05/02 20:58:27 brouard Exp $ */
1.126     brouard  1074: /* $State: Exp $ */
1.196     brouard  1075: #include "version.h"
                   1076: char version[]=__IMACH_VERSION__;
1.283     brouard  1077: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.289   ! brouard  1078: char fullversion[]="$Revision: 1.288 $ $Date: 2018/05/02 20:58:27 $"; 
1.126     brouard  1079: char strstart[80];
                   1080: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1081: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1082: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1083: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1084: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1085: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1086: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1087: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1088: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1089: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1090: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1091: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1092: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1093: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1094: int nsd=0; /**< Total number of single dummy variables (output) */
                   1095: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1096: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1097: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1098: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1099: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1100: int cptcov=0; /* Working variable */
1.218     brouard  1101: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1102: int npar=NPARMAX;
                   1103: int nlstate=2; /* Number of live states */
                   1104: int ndeath=1; /* Number of dead states */
1.130     brouard  1105: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1106: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1107: int popbased=0;
                   1108: 
                   1109: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1110: int maxwav=0; /* Maxim number of waves */
                   1111: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1112: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1113: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1114:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1115: int mle=1, weightopt=0;
1.126     brouard  1116: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1117: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1118: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1119:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1120: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1121: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1122: 
1.130     brouard  1123: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1124: double **matprod2(); /* test */
1.126     brouard  1125: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1126: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1127: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1128: 
1.136     brouard  1129: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1130: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1131: FILE *ficlog, *ficrespow;
1.130     brouard  1132: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1133: double fretone; /* Only one call to likelihood */
1.130     brouard  1134: long ipmx=0; /* Number of contributions */
1.126     brouard  1135: double sw; /* Sum of weights */
                   1136: char filerespow[FILENAMELENGTH];
                   1137: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1138: FILE *ficresilk;
                   1139: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1140: FILE *ficresprobmorprev;
                   1141: FILE *fichtm, *fichtmcov; /* Html File */
                   1142: FILE *ficreseij;
                   1143: char filerese[FILENAMELENGTH];
                   1144: FILE *ficresstdeij;
                   1145: char fileresstde[FILENAMELENGTH];
                   1146: FILE *ficrescveij;
                   1147: char filerescve[FILENAMELENGTH];
                   1148: FILE  *ficresvij;
                   1149: char fileresv[FILENAMELENGTH];
1.269     brouard  1150: 
1.126     brouard  1151: char title[MAXLINE];
1.234     brouard  1152: char model[MAXLINE]; /**< The model line */
1.217     brouard  1153: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1154: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1155: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1156: char command[FILENAMELENGTH];
                   1157: int  outcmd=0;
                   1158: 
1.217     brouard  1159: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1160: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1161: char filelog[FILENAMELENGTH]; /* Log file */
                   1162: char filerest[FILENAMELENGTH];
                   1163: char fileregp[FILENAMELENGTH];
                   1164: char popfile[FILENAMELENGTH];
                   1165: 
                   1166: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1167: 
1.157     brouard  1168: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1169: /* struct timezone tzp; */
                   1170: /* extern int gettimeofday(); */
                   1171: struct tm tml, *gmtime(), *localtime();
                   1172: 
                   1173: extern time_t time();
                   1174: 
                   1175: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1176: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1177: struct tm tm;
                   1178: 
1.126     brouard  1179: char strcurr[80], strfor[80];
                   1180: 
                   1181: char *endptr;
                   1182: long lval;
                   1183: double dval;
                   1184: 
                   1185: #define NR_END 1
                   1186: #define FREE_ARG char*
                   1187: #define FTOL 1.0e-10
                   1188: 
                   1189: #define NRANSI 
1.240     brouard  1190: #define ITMAX 200
                   1191: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1192: 
                   1193: #define TOL 2.0e-4 
                   1194: 
                   1195: #define CGOLD 0.3819660 
                   1196: #define ZEPS 1.0e-10 
                   1197: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1198: 
                   1199: #define GOLD 1.618034 
                   1200: #define GLIMIT 100.0 
                   1201: #define TINY 1.0e-20 
                   1202: 
                   1203: static double maxarg1,maxarg2;
                   1204: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1205: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1206:   
                   1207: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1208: #define rint(a) floor(a+0.5)
1.166     brouard  1209: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1210: #define mytinydouble 1.0e-16
1.166     brouard  1211: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1212: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1213: /* static double dsqrarg; */
                   1214: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1215: static double sqrarg;
                   1216: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1217: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1218: int agegomp= AGEGOMP;
                   1219: 
                   1220: int imx; 
                   1221: int stepm=1;
                   1222: /* Stepm, step in month: minimum step interpolation*/
                   1223: 
                   1224: int estepm;
                   1225: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1226: 
                   1227: int m,nb;
                   1228: long *num;
1.197     brouard  1229: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1230: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1231:                   covariate for which somebody answered excluding 
                   1232:                   undefined. Usually 2: 0 and 1. */
                   1233: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1234:                             covariate for which somebody answered including 
                   1235:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1236: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1237: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1238: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1239: double *ageexmed,*agecens;
                   1240: double dateintmean=0;
                   1241: 
                   1242: double *weight;
                   1243: int **s; /* Status */
1.141     brouard  1244: double *agedc;
1.145     brouard  1245: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1246:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1247:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1248: double **coqvar; /* Fixed quantitative covariate nqv */
                   1249: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1250: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1251: double  idx; 
                   1252: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1253: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1254: /*k          1  2   3   4     5    6    7     8    9 */
                   1255: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1256: /* Tndvar[k]    1   2   3               4          5 */
                   1257: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1258: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1259: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1260: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1261: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1262: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1263: /* Tprod[i]=k           4               7            */
                   1264: /* Tage[i]=k                  5               8      */
                   1265: /* */
                   1266: /* Type                    */
                   1267: /* V         1  2  3  4  5 */
                   1268: /*           F  F  V  V  V */
                   1269: /*           D  Q  D  D  Q */
                   1270: /*                         */
                   1271: int *TvarsD;
                   1272: int *TvarsDind;
                   1273: int *TvarsQ;
                   1274: int *TvarsQind;
                   1275: 
1.235     brouard  1276: #define MAXRESULTLINES 10
                   1277: int nresult=0;
1.258     brouard  1278: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1279: int TKresult[MAXRESULTLINES];
1.237     brouard  1280: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1281: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1282: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1283: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1284: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1285: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1286: 
1.234     brouard  1287: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1288: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1289: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1290: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1291: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1292: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1293: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1294: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1295: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1296: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1297: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1298: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1299: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1300: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1301: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1302: 
1.230     brouard  1303: int *Tvarsel; /**< Selected covariates for output */
                   1304: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1305: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1306: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1307: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1308: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1309: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1310: int *Tage;
1.227     brouard  1311: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1312: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1313: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1314: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1315: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1316: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1317: int **Tvard;
                   1318: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1319: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1320: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1321:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1322:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1323: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1324: double *lsurv, *lpop, *tpop;
                   1325: 
1.231     brouard  1326: #define FD 1; /* Fixed dummy covariate */
                   1327: #define FQ 2; /* Fixed quantitative covariate */
                   1328: #define FP 3; /* Fixed product covariate */
                   1329: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1330: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1331: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1332: #define VD 10; /* Varying dummy covariate */
                   1333: #define VQ 11; /* Varying quantitative covariate */
                   1334: #define VP 12; /* Varying product covariate */
                   1335: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1336: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1337: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1338: #define APFD 16; /* Age product * fixed dummy covariate */
                   1339: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1340: #define APVD 18; /* Age product * varying dummy covariate */
                   1341: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1342: 
                   1343: #define FTYPE 1; /* Fixed covariate */
                   1344: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1345: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1346: 
                   1347: struct kmodel{
                   1348:        int maintype; /* main type */
                   1349:        int subtype; /* subtype */
                   1350: };
                   1351: struct kmodel modell[NCOVMAX];
                   1352: 
1.143     brouard  1353: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1354: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1355: 
                   1356: /**************** split *************************/
                   1357: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1358: {
                   1359:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1360:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1361:   */ 
                   1362:   char *ss;                            /* pointer */
1.186     brouard  1363:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1364: 
                   1365:   l1 = strlen(path );                  /* length of path */
                   1366:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1367:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1368:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1369:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1370:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1371:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1372:     /* get current working directory */
                   1373:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1374: #ifdef WIN32
                   1375:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1376: #else
                   1377:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1378: #endif
1.126     brouard  1379:       return( GLOCK_ERROR_GETCWD );
                   1380:     }
                   1381:     /* got dirc from getcwd*/
                   1382:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1383:   } else {                             /* strip directory from path */
1.126     brouard  1384:     ss++;                              /* after this, the filename */
                   1385:     l2 = strlen( ss );                 /* length of filename */
                   1386:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1387:     strcpy( name, ss );                /* save file name */
                   1388:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1389:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1390:     printf(" DIRC2 = %s \n",dirc);
                   1391:   }
                   1392:   /* We add a separator at the end of dirc if not exists */
                   1393:   l1 = strlen( dirc );                 /* length of directory */
                   1394:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1395:     dirc[l1] =  DIRSEPARATOR;
                   1396:     dirc[l1+1] = 0; 
                   1397:     printf(" DIRC3 = %s \n",dirc);
                   1398:   }
                   1399:   ss = strrchr( name, '.' );           /* find last / */
                   1400:   if (ss >0){
                   1401:     ss++;
                   1402:     strcpy(ext,ss);                    /* save extension */
                   1403:     l1= strlen( name);
                   1404:     l2= strlen(ss)+1;
                   1405:     strncpy( finame, name, l1-l2);
                   1406:     finame[l1-l2]= 0;
                   1407:   }
                   1408: 
                   1409:   return( 0 );                         /* we're done */
                   1410: }
                   1411: 
                   1412: 
                   1413: /******************************************/
                   1414: 
                   1415: void replace_back_to_slash(char *s, char*t)
                   1416: {
                   1417:   int i;
                   1418:   int lg=0;
                   1419:   i=0;
                   1420:   lg=strlen(t);
                   1421:   for(i=0; i<= lg; i++) {
                   1422:     (s[i] = t[i]);
                   1423:     if (t[i]== '\\') s[i]='/';
                   1424:   }
                   1425: }
                   1426: 
1.132     brouard  1427: char *trimbb(char *out, char *in)
1.137     brouard  1428: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1429:   char *s;
                   1430:   s=out;
                   1431:   while (*in != '\0'){
1.137     brouard  1432:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1433:       in++;
                   1434:     }
                   1435:     *out++ = *in++;
                   1436:   }
                   1437:   *out='\0';
                   1438:   return s;
                   1439: }
                   1440: 
1.187     brouard  1441: /* char *substrchaine(char *out, char *in, char *chain) */
                   1442: /* { */
                   1443: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1444: /*   char *s, *t; */
                   1445: /*   t=in;s=out; */
                   1446: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1447: /*     *out++ = *in++; */
                   1448: /*   } */
                   1449: 
                   1450: /*   /\* *in matches *chain *\/ */
                   1451: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1452: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1453: /*   } */
                   1454: /*   in--; chain--; */
                   1455: /*   while ( (*in != '\0')){ */
                   1456: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1457: /*     *out++ = *in++; */
                   1458: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1459: /*   } */
                   1460: /*   *out='\0'; */
                   1461: /*   out=s; */
                   1462: /*   return out; */
                   1463: /* } */
                   1464: char *substrchaine(char *out, char *in, char *chain)
                   1465: {
                   1466:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1467:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1468: 
                   1469:   char *strloc;
                   1470: 
                   1471:   strcpy (out, in); 
                   1472:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1473:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1474:   if(strloc != NULL){ 
                   1475:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1476:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1477:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1478:   }
                   1479:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1480:   return out;
                   1481: }
                   1482: 
                   1483: 
1.145     brouard  1484: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1485: {
1.187     brouard  1486:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1487:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1488:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1489:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1490:   */
1.160     brouard  1491:   char *s, *t;
1.145     brouard  1492:   t=in;s=in;
                   1493:   while ((*in != occ) && (*in != '\0')){
                   1494:     *alocc++ = *in++;
                   1495:   }
                   1496:   if( *in == occ){
                   1497:     *(alocc)='\0';
                   1498:     s=++in;
                   1499:   }
                   1500:  
                   1501:   if (s == t) {/* occ not found */
                   1502:     *(alocc-(in-s))='\0';
                   1503:     in=s;
                   1504:   }
                   1505:   while ( *in != '\0'){
                   1506:     *blocc++ = *in++;
                   1507:   }
                   1508: 
                   1509:   *blocc='\0';
                   1510:   return t;
                   1511: }
1.137     brouard  1512: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1513: {
1.187     brouard  1514:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1515:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1516:      gives blocc="abcdef2ghi" and alocc="j".
                   1517:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1518:   */
                   1519:   char *s, *t;
                   1520:   t=in;s=in;
                   1521:   while (*in != '\0'){
                   1522:     while( *in == occ){
                   1523:       *blocc++ = *in++;
                   1524:       s=in;
                   1525:     }
                   1526:     *blocc++ = *in++;
                   1527:   }
                   1528:   if (s == t) /* occ not found */
                   1529:     *(blocc-(in-s))='\0';
                   1530:   else
                   1531:     *(blocc-(in-s)-1)='\0';
                   1532:   in=s;
                   1533:   while ( *in != '\0'){
                   1534:     *alocc++ = *in++;
                   1535:   }
                   1536: 
                   1537:   *alocc='\0';
                   1538:   return s;
                   1539: }
                   1540: 
1.126     brouard  1541: int nbocc(char *s, char occ)
                   1542: {
                   1543:   int i,j=0;
                   1544:   int lg=20;
                   1545:   i=0;
                   1546:   lg=strlen(s);
                   1547:   for(i=0; i<= lg; i++) {
1.234     brouard  1548:     if  (s[i] == occ ) j++;
1.126     brouard  1549:   }
                   1550:   return j;
                   1551: }
                   1552: 
1.137     brouard  1553: /* void cutv(char *u,char *v, char*t, char occ) */
                   1554: /* { */
                   1555: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1556: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1557: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1558: /*   int i,lg,j,p=0; */
                   1559: /*   i=0; */
                   1560: /*   lg=strlen(t); */
                   1561: /*   for(j=0; j<=lg-1; j++) { */
                   1562: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1563: /*   } */
1.126     brouard  1564: 
1.137     brouard  1565: /*   for(j=0; j<p; j++) { */
                   1566: /*     (u[j] = t[j]); */
                   1567: /*   } */
                   1568: /*      u[p]='\0'; */
1.126     brouard  1569: 
1.137     brouard  1570: /*    for(j=0; j<= lg; j++) { */
                   1571: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1572: /*   } */
                   1573: /* } */
1.126     brouard  1574: 
1.160     brouard  1575: #ifdef _WIN32
                   1576: char * strsep(char **pp, const char *delim)
                   1577: {
                   1578:   char *p, *q;
                   1579:          
                   1580:   if ((p = *pp) == NULL)
                   1581:     return 0;
                   1582:   if ((q = strpbrk (p, delim)) != NULL)
                   1583:   {
                   1584:     *pp = q + 1;
                   1585:     *q = '\0';
                   1586:   }
                   1587:   else
                   1588:     *pp = 0;
                   1589:   return p;
                   1590: }
                   1591: #endif
                   1592: 
1.126     brouard  1593: /********************** nrerror ********************/
                   1594: 
                   1595: void nrerror(char error_text[])
                   1596: {
                   1597:   fprintf(stderr,"ERREUR ...\n");
                   1598:   fprintf(stderr,"%s\n",error_text);
                   1599:   exit(EXIT_FAILURE);
                   1600: }
                   1601: /*********************** vector *******************/
                   1602: double *vector(int nl, int nh)
                   1603: {
                   1604:   double *v;
                   1605:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1606:   if (!v) nrerror("allocation failure in vector");
                   1607:   return v-nl+NR_END;
                   1608: }
                   1609: 
                   1610: /************************ free vector ******************/
                   1611: void free_vector(double*v, int nl, int nh)
                   1612: {
                   1613:   free((FREE_ARG)(v+nl-NR_END));
                   1614: }
                   1615: 
                   1616: /************************ivector *******************************/
                   1617: int *ivector(long nl,long nh)
                   1618: {
                   1619:   int *v;
                   1620:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1621:   if (!v) nrerror("allocation failure in ivector");
                   1622:   return v-nl+NR_END;
                   1623: }
                   1624: 
                   1625: /******************free ivector **************************/
                   1626: void free_ivector(int *v, long nl, long nh)
                   1627: {
                   1628:   free((FREE_ARG)(v+nl-NR_END));
                   1629: }
                   1630: 
                   1631: /************************lvector *******************************/
                   1632: long *lvector(long nl,long nh)
                   1633: {
                   1634:   long *v;
                   1635:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1636:   if (!v) nrerror("allocation failure in ivector");
                   1637:   return v-nl+NR_END;
                   1638: }
                   1639: 
                   1640: /******************free lvector **************************/
                   1641: void free_lvector(long *v, long nl, long nh)
                   1642: {
                   1643:   free((FREE_ARG)(v+nl-NR_END));
                   1644: }
                   1645: 
                   1646: /******************* imatrix *******************************/
                   1647: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1648:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1649: { 
                   1650:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1651:   int **m; 
                   1652:   
                   1653:   /* allocate pointers to rows */ 
                   1654:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1655:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1656:   m += NR_END; 
                   1657:   m -= nrl; 
                   1658:   
                   1659:   
                   1660:   /* allocate rows and set pointers to them */ 
                   1661:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1662:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1663:   m[nrl] += NR_END; 
                   1664:   m[nrl] -= ncl; 
                   1665:   
                   1666:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1667:   
                   1668:   /* return pointer to array of pointers to rows */ 
                   1669:   return m; 
                   1670: } 
                   1671: 
                   1672: /****************** free_imatrix *************************/
                   1673: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1674:       int **m;
                   1675:       long nch,ncl,nrh,nrl; 
                   1676:      /* free an int matrix allocated by imatrix() */ 
                   1677: { 
                   1678:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1679:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1680: } 
                   1681: 
                   1682: /******************* matrix *******************************/
                   1683: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1684: {
                   1685:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1686:   double **m;
                   1687: 
                   1688:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1689:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1690:   m += NR_END;
                   1691:   m -= nrl;
                   1692: 
                   1693:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1694:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1695:   m[nrl] += NR_END;
                   1696:   m[nrl] -= ncl;
                   1697: 
                   1698:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1699:   return m;
1.145     brouard  1700:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1701: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1702: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1703:    */
                   1704: }
                   1705: 
                   1706: /*************************free matrix ************************/
                   1707: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1708: {
                   1709:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1710:   free((FREE_ARG)(m+nrl-NR_END));
                   1711: }
                   1712: 
                   1713: /******************* ma3x *******************************/
                   1714: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1715: {
                   1716:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1717:   double ***m;
                   1718: 
                   1719:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1720:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1721:   m += NR_END;
                   1722:   m -= nrl;
                   1723: 
                   1724:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1725:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1726:   m[nrl] += NR_END;
                   1727:   m[nrl] -= ncl;
                   1728: 
                   1729:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1730: 
                   1731:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1732:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1733:   m[nrl][ncl] += NR_END;
                   1734:   m[nrl][ncl] -= nll;
                   1735:   for (j=ncl+1; j<=nch; j++) 
                   1736:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1737:   
                   1738:   for (i=nrl+1; i<=nrh; i++) {
                   1739:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1740:     for (j=ncl+1; j<=nch; j++) 
                   1741:       m[i][j]=m[i][j-1]+nlay;
                   1742:   }
                   1743:   return m; 
                   1744:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1745:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1746:   */
                   1747: }
                   1748: 
                   1749: /*************************free ma3x ************************/
                   1750: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1751: {
                   1752:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1753:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1754:   free((FREE_ARG)(m+nrl-NR_END));
                   1755: }
                   1756: 
                   1757: /*************** function subdirf ***********/
                   1758: char *subdirf(char fileres[])
                   1759: {
                   1760:   /* Caution optionfilefiname is hidden */
                   1761:   strcpy(tmpout,optionfilefiname);
                   1762:   strcat(tmpout,"/"); /* Add to the right */
                   1763:   strcat(tmpout,fileres);
                   1764:   return tmpout;
                   1765: }
                   1766: 
                   1767: /*************** function subdirf2 ***********/
                   1768: char *subdirf2(char fileres[], char *preop)
                   1769: {
                   1770:   
                   1771:   /* Caution optionfilefiname is hidden */
                   1772:   strcpy(tmpout,optionfilefiname);
                   1773:   strcat(tmpout,"/");
                   1774:   strcat(tmpout,preop);
                   1775:   strcat(tmpout,fileres);
                   1776:   return tmpout;
                   1777: }
                   1778: 
                   1779: /*************** function subdirf3 ***********/
                   1780: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1781: {
                   1782:   
                   1783:   /* Caution optionfilefiname is hidden */
                   1784:   strcpy(tmpout,optionfilefiname);
                   1785:   strcat(tmpout,"/");
                   1786:   strcat(tmpout,preop);
                   1787:   strcat(tmpout,preop2);
                   1788:   strcat(tmpout,fileres);
                   1789:   return tmpout;
                   1790: }
1.213     brouard  1791:  
                   1792: /*************** function subdirfext ***********/
                   1793: char *subdirfext(char fileres[], char *preop, char *postop)
                   1794: {
                   1795:   
                   1796:   strcpy(tmpout,preop);
                   1797:   strcat(tmpout,fileres);
                   1798:   strcat(tmpout,postop);
                   1799:   return tmpout;
                   1800: }
1.126     brouard  1801: 
1.213     brouard  1802: /*************** function subdirfext3 ***********/
                   1803: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1804: {
                   1805:   
                   1806:   /* Caution optionfilefiname is hidden */
                   1807:   strcpy(tmpout,optionfilefiname);
                   1808:   strcat(tmpout,"/");
                   1809:   strcat(tmpout,preop);
                   1810:   strcat(tmpout,fileres);
                   1811:   strcat(tmpout,postop);
                   1812:   return tmpout;
                   1813: }
                   1814:  
1.162     brouard  1815: char *asc_diff_time(long time_sec, char ascdiff[])
                   1816: {
                   1817:   long sec_left, days, hours, minutes;
                   1818:   days = (time_sec) / (60*60*24);
                   1819:   sec_left = (time_sec) % (60*60*24);
                   1820:   hours = (sec_left) / (60*60) ;
                   1821:   sec_left = (sec_left) %(60*60);
                   1822:   minutes = (sec_left) /60;
                   1823:   sec_left = (sec_left) % (60);
                   1824:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1825:   return ascdiff;
                   1826: }
                   1827: 
1.126     brouard  1828: /***************** f1dim *************************/
                   1829: extern int ncom; 
                   1830: extern double *pcom,*xicom;
                   1831: extern double (*nrfunc)(double []); 
                   1832:  
                   1833: double f1dim(double x) 
                   1834: { 
                   1835:   int j; 
                   1836:   double f;
                   1837:   double *xt; 
                   1838:  
                   1839:   xt=vector(1,ncom); 
                   1840:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1841:   f=(*nrfunc)(xt); 
                   1842:   free_vector(xt,1,ncom); 
                   1843:   return f; 
                   1844: } 
                   1845: 
                   1846: /*****************brent *************************/
                   1847: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1848: {
                   1849:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1850:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1851:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1852:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1853:    * returned function value. 
                   1854:   */
1.126     brouard  1855:   int iter; 
                   1856:   double a,b,d,etemp;
1.159     brouard  1857:   double fu=0,fv,fw,fx;
1.164     brouard  1858:   double ftemp=0.;
1.126     brouard  1859:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1860:   double e=0.0; 
                   1861:  
                   1862:   a=(ax < cx ? ax : cx); 
                   1863:   b=(ax > cx ? ax : cx); 
                   1864:   x=w=v=bx; 
                   1865:   fw=fv=fx=(*f)(x); 
                   1866:   for (iter=1;iter<=ITMAX;iter++) { 
                   1867:     xm=0.5*(a+b); 
                   1868:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1869:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1870:     printf(".");fflush(stdout);
                   1871:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1872: #ifdef DEBUGBRENT
1.126     brouard  1873:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1874:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1875:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1876: #endif
                   1877:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1878:       *xmin=x; 
                   1879:       return fx; 
                   1880:     } 
                   1881:     ftemp=fu;
                   1882:     if (fabs(e) > tol1) { 
                   1883:       r=(x-w)*(fx-fv); 
                   1884:       q=(x-v)*(fx-fw); 
                   1885:       p=(x-v)*q-(x-w)*r; 
                   1886:       q=2.0*(q-r); 
                   1887:       if (q > 0.0) p = -p; 
                   1888:       q=fabs(q); 
                   1889:       etemp=e; 
                   1890:       e=d; 
                   1891:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1892:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1893:       else { 
1.224     brouard  1894:                                d=p/q; 
                   1895:                                u=x+d; 
                   1896:                                if (u-a < tol2 || b-u < tol2) 
                   1897:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1898:       } 
                   1899:     } else { 
                   1900:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1901:     } 
                   1902:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1903:     fu=(*f)(u); 
                   1904:     if (fu <= fx) { 
                   1905:       if (u >= x) a=x; else b=x; 
                   1906:       SHFT(v,w,x,u) 
1.183     brouard  1907:       SHFT(fv,fw,fx,fu) 
                   1908:     } else { 
                   1909:       if (u < x) a=u; else b=u; 
                   1910:       if (fu <= fw || w == x) { 
1.224     brouard  1911:                                v=w; 
                   1912:                                w=u; 
                   1913:                                fv=fw; 
                   1914:                                fw=fu; 
1.183     brouard  1915:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1916:                                v=u; 
                   1917:                                fv=fu; 
1.183     brouard  1918:       } 
                   1919:     } 
1.126     brouard  1920:   } 
                   1921:   nrerror("Too many iterations in brent"); 
                   1922:   *xmin=x; 
                   1923:   return fx; 
                   1924: } 
                   1925: 
                   1926: /****************** mnbrak ***********************/
                   1927: 
                   1928: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1929:            double (*func)(double)) 
1.183     brouard  1930: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1931: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1932: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1933: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1934:    */
1.126     brouard  1935:   double ulim,u,r,q, dum;
                   1936:   double fu; 
1.187     brouard  1937: 
                   1938:   double scale=10.;
                   1939:   int iterscale=0;
                   1940: 
                   1941:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1942:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1943: 
                   1944: 
                   1945:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1946:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1947:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1948:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1949:   /* } */
                   1950: 
1.126     brouard  1951:   if (*fb > *fa) { 
                   1952:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1953:     SHFT(dum,*fb,*fa,dum) 
                   1954:   } 
1.126     brouard  1955:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1956:   *fc=(*func)(*cx); 
1.183     brouard  1957: #ifdef DEBUG
1.224     brouard  1958:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1959:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1960: #endif
1.224     brouard  1961:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1962:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1963:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1964:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1965:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1966:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1967:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1968:       fu=(*func)(u); 
1.163     brouard  1969: #ifdef DEBUG
                   1970:       /* f(x)=A(x-u)**2+f(u) */
                   1971:       double A, fparabu; 
                   1972:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1973:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1974:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1975:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1976:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1977:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1978:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1979:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1980: #endif 
1.184     brouard  1981: #ifdef MNBRAKORIGINAL
1.183     brouard  1982: #else
1.191     brouard  1983: /*       if (fu > *fc) { */
                   1984: /* #ifdef DEBUG */
                   1985: /*       printf("mnbrak4  fu > fc \n"); */
                   1986: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1987: /* #endif */
                   1988: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1989: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1990: /*     dum=u; /\* Shifting c and u *\/ */
                   1991: /*     u = *cx; */
                   1992: /*     *cx = dum; */
                   1993: /*     dum = fu; */
                   1994: /*     fu = *fc; */
                   1995: /*     *fc =dum; */
                   1996: /*       } else { /\* end *\/ */
                   1997: /* #ifdef DEBUG */
                   1998: /*       printf("mnbrak3  fu < fc \n"); */
                   1999: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2000: /* #endif */
                   2001: /*     dum=u; /\* Shifting c and u *\/ */
                   2002: /*     u = *cx; */
                   2003: /*     *cx = dum; */
                   2004: /*     dum = fu; */
                   2005: /*     fu = *fc; */
                   2006: /*     *fc =dum; */
                   2007: /*       } */
1.224     brouard  2008: #ifdef DEBUGMNBRAK
                   2009:                 double A, fparabu; 
                   2010:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2011:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2012:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2013:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2014: #endif
1.191     brouard  2015:       dum=u; /* Shifting c and u */
                   2016:       u = *cx;
                   2017:       *cx = dum;
                   2018:       dum = fu;
                   2019:       fu = *fc;
                   2020:       *fc =dum;
1.183     brouard  2021: #endif
1.162     brouard  2022:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2023: #ifdef DEBUG
1.224     brouard  2024:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2025:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2026: #endif
1.126     brouard  2027:       fu=(*func)(u); 
                   2028:       if (fu < *fc) { 
1.183     brouard  2029: #ifdef DEBUG
1.224     brouard  2030:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2031:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2032: #endif
                   2033:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2034:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2035: #ifdef DEBUG
                   2036:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2037: #endif
                   2038:       } 
1.162     brouard  2039:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2040: #ifdef DEBUG
1.224     brouard  2041:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2042:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2043: #endif
1.126     brouard  2044:       u=ulim; 
                   2045:       fu=(*func)(u); 
1.183     brouard  2046:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2047: #ifdef DEBUG
1.224     brouard  2048:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2049:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2050: #endif
1.126     brouard  2051:       u=(*cx)+GOLD*(*cx-*bx); 
                   2052:       fu=(*func)(u); 
1.224     brouard  2053: #ifdef DEBUG
                   2054:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2055:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2056: #endif
1.183     brouard  2057:     } /* end tests */
1.126     brouard  2058:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2059:     SHFT(*fa,*fb,*fc,fu) 
                   2060: #ifdef DEBUG
1.224     brouard  2061:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2062:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2063: #endif
                   2064:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2065: } 
                   2066: 
                   2067: /*************** linmin ************************/
1.162     brouard  2068: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2069: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2070: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2071: the value of func at the returned location p . This is actually all accomplished by calling the
                   2072: routines mnbrak and brent .*/
1.126     brouard  2073: int ncom; 
                   2074: double *pcom,*xicom;
                   2075: double (*nrfunc)(double []); 
                   2076:  
1.224     brouard  2077: #ifdef LINMINORIGINAL
1.126     brouard  2078: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2079: #else
                   2080: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2081: #endif
1.126     brouard  2082: { 
                   2083:   double brent(double ax, double bx, double cx, 
                   2084:               double (*f)(double), double tol, double *xmin); 
                   2085:   double f1dim(double x); 
                   2086:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2087:              double *fc, double (*func)(double)); 
                   2088:   int j; 
                   2089:   double xx,xmin,bx,ax; 
                   2090:   double fx,fb,fa;
1.187     brouard  2091: 
1.203     brouard  2092: #ifdef LINMINORIGINAL
                   2093: #else
                   2094:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2095: #endif
                   2096:   
1.126     brouard  2097:   ncom=n; 
                   2098:   pcom=vector(1,n); 
                   2099:   xicom=vector(1,n); 
                   2100:   nrfunc=func; 
                   2101:   for (j=1;j<=n;j++) { 
                   2102:     pcom[j]=p[j]; 
1.202     brouard  2103:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2104:   } 
1.187     brouard  2105: 
1.203     brouard  2106: #ifdef LINMINORIGINAL
                   2107:   xx=1.;
                   2108: #else
                   2109:   axs=0.0;
                   2110:   xxs=1.;
                   2111:   do{
                   2112:     xx= xxs;
                   2113: #endif
1.187     brouard  2114:     ax=0.;
                   2115:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2116:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2117:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2118:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2119:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2120:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2121:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2122: #ifdef LINMINORIGINAL
                   2123: #else
                   2124:     if (fx != fx){
1.224     brouard  2125:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2126:                        printf("|");
                   2127:                        fprintf(ficlog,"|");
1.203     brouard  2128: #ifdef DEBUGLINMIN
1.224     brouard  2129:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2130: #endif
                   2131:     }
1.224     brouard  2132:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2133: #endif
                   2134:   
1.191     brouard  2135: #ifdef DEBUGLINMIN
                   2136:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2137:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2138: #endif
1.224     brouard  2139: #ifdef LINMINORIGINAL
                   2140: #else
                   2141:        if(fb == fx){ /* Flat function in the direction */
                   2142:                xmin=xx;
                   2143:     *flat=1;
                   2144:        }else{
                   2145:     *flat=0;
                   2146: #endif
                   2147:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2148:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2149:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2150:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2151:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2152:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2153: #ifdef DEBUG
1.224     brouard  2154:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2155:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2156: #endif
                   2157: #ifdef LINMINORIGINAL
                   2158: #else
                   2159:                        }
1.126     brouard  2160: #endif
1.191     brouard  2161: #ifdef DEBUGLINMIN
                   2162:   printf("linmin end ");
1.202     brouard  2163:   fprintf(ficlog,"linmin end ");
1.191     brouard  2164: #endif
1.126     brouard  2165:   for (j=1;j<=n;j++) { 
1.203     brouard  2166: #ifdef LINMINORIGINAL
                   2167:     xi[j] *= xmin; 
                   2168: #else
                   2169: #ifdef DEBUGLINMIN
                   2170:     if(xxs <1.0)
                   2171:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2172: #endif
                   2173:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2174: #ifdef DEBUGLINMIN
                   2175:     if(xxs <1.0)
                   2176:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2177: #endif
                   2178: #endif
1.187     brouard  2179:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2180:   } 
1.191     brouard  2181: #ifdef DEBUGLINMIN
1.203     brouard  2182:   printf("\n");
1.191     brouard  2183:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2184:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2185:   for (j=1;j<=n;j++) { 
1.202     brouard  2186:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2187:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2188:     if(j % ncovmodel == 0){
1.191     brouard  2189:       printf("\n");
1.202     brouard  2190:       fprintf(ficlog,"\n");
                   2191:     }
1.191     brouard  2192:   }
1.203     brouard  2193: #else
1.191     brouard  2194: #endif
1.126     brouard  2195:   free_vector(xicom,1,n); 
                   2196:   free_vector(pcom,1,n); 
                   2197: } 
                   2198: 
                   2199: 
                   2200: /*************** powell ************************/
1.162     brouard  2201: /*
                   2202: Minimization of a function func of n variables. Input consists of an initial starting point
                   2203: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2204: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2205: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2206: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2207: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2208:  */
1.224     brouard  2209: #ifdef LINMINORIGINAL
                   2210: #else
                   2211:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2212:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2213: #endif
1.126     brouard  2214: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2215:            double (*func)(double [])) 
                   2216: { 
1.224     brouard  2217: #ifdef LINMINORIGINAL
                   2218:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2219:              double (*func)(double [])); 
1.224     brouard  2220: #else 
1.241     brouard  2221:  void linmin(double p[], double xi[], int n, double *fret,
                   2222:             double (*func)(double []),int *flat); 
1.224     brouard  2223: #endif
1.239     brouard  2224:  int i,ibig,j,jk,k; 
1.126     brouard  2225:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2226:   double directest;
1.126     brouard  2227:   double fp,fptt;
                   2228:   double *xits;
                   2229:   int niterf, itmp;
1.224     brouard  2230: #ifdef LINMINORIGINAL
                   2231: #else
                   2232: 
                   2233:   flatdir=ivector(1,n); 
                   2234:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2235: #endif
1.126     brouard  2236: 
                   2237:   pt=vector(1,n); 
                   2238:   ptt=vector(1,n); 
                   2239:   xit=vector(1,n); 
                   2240:   xits=vector(1,n); 
                   2241:   *fret=(*func)(p); 
                   2242:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2243:   rcurr_time = time(NULL);  
1.126     brouard  2244:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2245:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2246:     ibig=0; 
                   2247:     del=0.0; 
1.157     brouard  2248:     rlast_time=rcurr_time;
                   2249:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2250:     rcurr_time = time(NULL);  
                   2251:     curr_time = *localtime(&rcurr_time);
                   2252:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2253:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2254: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2255:     for (i=1;i<=n;i++) {
1.126     brouard  2256:       fprintf(ficrespow," %.12lf", p[i]);
                   2257:     }
1.239     brouard  2258:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2259:     printf("\n#model=  1      +     age ");
                   2260:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2261:     if(nagesqr==1){
1.241     brouard  2262:        printf("  + age*age  ");
                   2263:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2264:     }
                   2265:     for(j=1;j <=ncovmodel-2;j++){
                   2266:       if(Typevar[j]==0) {
                   2267:        printf("  +      V%d  ",Tvar[j]);
                   2268:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2269:       }else if(Typevar[j]==1) {
                   2270:        printf("  +    V%d*age ",Tvar[j]);
                   2271:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2272:       }else if(Typevar[j]==2) {
                   2273:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2274:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2275:       }
                   2276:     }
1.126     brouard  2277:     printf("\n");
1.239     brouard  2278: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2279: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2280:     fprintf(ficlog,"\n");
1.239     brouard  2281:     for(i=1,jk=1; i <=nlstate; i++){
                   2282:       for(k=1; k <=(nlstate+ndeath); k++){
                   2283:        if (k != i) {
                   2284:          printf("%d%d ",i,k);
                   2285:          fprintf(ficlog,"%d%d ",i,k);
                   2286:          for(j=1; j <=ncovmodel; j++){
                   2287:            printf("%12.7f ",p[jk]);
                   2288:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2289:            jk++; 
                   2290:          }
                   2291:          printf("\n");
                   2292:          fprintf(ficlog,"\n");
                   2293:        }
                   2294:       }
                   2295:     }
1.241     brouard  2296:     if(*iter <=3 && *iter >1){
1.157     brouard  2297:       tml = *localtime(&rcurr_time);
                   2298:       strcpy(strcurr,asctime(&tml));
                   2299:       rforecast_time=rcurr_time; 
1.126     brouard  2300:       itmp = strlen(strcurr);
                   2301:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2302:        strcurr[itmp-1]='\0';
1.162     brouard  2303:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2304:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2305:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2306:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2307:        forecast_time = *localtime(&rforecast_time);
                   2308:        strcpy(strfor,asctime(&forecast_time));
                   2309:        itmp = strlen(strfor);
                   2310:        if(strfor[itmp-1]=='\n')
                   2311:          strfor[itmp-1]='\0';
                   2312:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2313:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2314:       }
                   2315:     }
1.187     brouard  2316:     for (i=1;i<=n;i++) { /* For each direction i */
                   2317:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2318:       fptt=(*fret); 
                   2319: #ifdef DEBUG
1.203     brouard  2320:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2321:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2322: #endif
1.203     brouard  2323:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2324:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2325: #ifdef LINMINORIGINAL
1.188     brouard  2326:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2327: #else
                   2328:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2329:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2330: #endif
                   2331:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2332:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2333:                                /* because that direction will be replaced unless the gain del is small */
                   2334:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2335:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2336:                                /* with the new direction. */
                   2337:                                del=fabs(fptt-(*fret)); 
                   2338:                                ibig=i; 
1.126     brouard  2339:       } 
                   2340: #ifdef DEBUG
                   2341:       printf("%d %.12e",i,(*fret));
                   2342:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2343:       for (j=1;j<=n;j++) {
1.224     brouard  2344:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2345:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2346:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2347:       }
                   2348:       for(j=1;j<=n;j++) {
1.225     brouard  2349:                                printf(" p(%d)=%.12e",j,p[j]);
                   2350:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2351:       }
                   2352:       printf("\n");
                   2353:       fprintf(ficlog,"\n");
                   2354: #endif
1.187     brouard  2355:     } /* end loop on each direction i */
                   2356:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2357:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2358:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2359:       for(j=1;j<=n;j++) {
1.225     brouard  2360:                                if(flatdir[j] >0){
                   2361:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2362:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2363:                                }
                   2364:                                /* printf("\n"); */
                   2365:                                /* fprintf(ficlog,"\n"); */
                   2366:                        }
1.243     brouard  2367:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2368:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2369:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2370:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2371:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2372:       /* decreased of more than 3.84  */
                   2373:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2374:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2375:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2376:                        
1.188     brouard  2377:       /* Starting the program with initial values given by a former maximization will simply change */
                   2378:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2379:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2380:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2381: #ifdef DEBUG
                   2382:       int k[2],l;
                   2383:       k[0]=1;
                   2384:       k[1]=-1;
                   2385:       printf("Max: %.12e",(*func)(p));
                   2386:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2387:       for (j=1;j<=n;j++) {
                   2388:        printf(" %.12e",p[j]);
                   2389:        fprintf(ficlog," %.12e",p[j]);
                   2390:       }
                   2391:       printf("\n");
                   2392:       fprintf(ficlog,"\n");
                   2393:       for(l=0;l<=1;l++) {
                   2394:        for (j=1;j<=n;j++) {
                   2395:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2396:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2397:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2398:        }
                   2399:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2400:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2401:       }
                   2402: #endif
                   2403: 
1.224     brouard  2404: #ifdef LINMINORIGINAL
                   2405: #else
                   2406:       free_ivector(flatdir,1,n); 
                   2407: #endif
1.126     brouard  2408:       free_vector(xit,1,n); 
                   2409:       free_vector(xits,1,n); 
                   2410:       free_vector(ptt,1,n); 
                   2411:       free_vector(pt,1,n); 
                   2412:       return; 
1.192     brouard  2413:     } /* enough precision */ 
1.240     brouard  2414:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2415:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2416:       ptt[j]=2.0*p[j]-pt[j]; 
                   2417:       xit[j]=p[j]-pt[j]; 
                   2418:       pt[j]=p[j]; 
                   2419:     } 
1.181     brouard  2420:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2421: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2422:                if (*iter <=4) {
1.225     brouard  2423: #else
                   2424: #endif
1.224     brouard  2425: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2426: #else
1.161     brouard  2427:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2428: #endif
1.162     brouard  2429:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2430:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2431:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2432:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2433:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2434:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2435:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2436:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2437:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2438:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2439:       /* mu² and del² are equal when f3=f1 */
                   2440:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2441:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2442:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2443:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2444: #ifdef NRCORIGINAL
                   2445:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2446: #else
                   2447:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2448:       t= t- del*SQR(fp-fptt);
1.183     brouard  2449: #endif
1.202     brouard  2450:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2451: #ifdef DEBUG
1.181     brouard  2452:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2453:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2454:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2455:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2456:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2457:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2458:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2459:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2460: #endif
1.183     brouard  2461: #ifdef POWELLORIGINAL
                   2462:       if (t < 0.0) { /* Then we use it for new direction */
                   2463: #else
1.182     brouard  2464:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2465:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2466:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2467:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2468:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2469:       } 
1.181     brouard  2470:       if (directest < 0.0) { /* Then we use it for new direction */
                   2471: #endif
1.191     brouard  2472: #ifdef DEBUGLINMIN
1.234     brouard  2473:        printf("Before linmin in direction P%d-P0\n",n);
                   2474:        for (j=1;j<=n;j++) {
                   2475:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2476:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2477:          if(j % ncovmodel == 0){
                   2478:            printf("\n");
                   2479:            fprintf(ficlog,"\n");
                   2480:          }
                   2481:        }
1.224     brouard  2482: #endif
                   2483: #ifdef LINMINORIGINAL
1.234     brouard  2484:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2485: #else
1.234     brouard  2486:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2487:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2488: #endif
1.234     brouard  2489:        
1.191     brouard  2490: #ifdef DEBUGLINMIN
1.234     brouard  2491:        for (j=1;j<=n;j++) { 
                   2492:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2493:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2494:          if(j % ncovmodel == 0){
                   2495:            printf("\n");
                   2496:            fprintf(ficlog,"\n");
                   2497:          }
                   2498:        }
1.224     brouard  2499: #endif
1.234     brouard  2500:        for (j=1;j<=n;j++) { 
                   2501:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2502:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2503:        }
1.224     brouard  2504: #ifdef LINMINORIGINAL
                   2505: #else
1.234     brouard  2506:        for (j=1, flatd=0;j<=n;j++) {
                   2507:          if(flatdir[j]>0)
                   2508:            flatd++;
                   2509:        }
                   2510:        if(flatd >0){
1.255     brouard  2511:          printf("%d flat directions: ",flatd);
                   2512:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2513:          for (j=1;j<=n;j++) { 
                   2514:            if(flatdir[j]>0){
                   2515:              printf("%d ",j);
                   2516:              fprintf(ficlog,"%d ",j);
                   2517:            }
                   2518:          }
                   2519:          printf("\n");
                   2520:          fprintf(ficlog,"\n");
                   2521:        }
1.191     brouard  2522: #endif
1.234     brouard  2523:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2524:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2525:        
1.126     brouard  2526: #ifdef DEBUG
1.234     brouard  2527:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2528:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2529:        for(j=1;j<=n;j++){
                   2530:          printf(" %lf",xit[j]);
                   2531:          fprintf(ficlog," %lf",xit[j]);
                   2532:        }
                   2533:        printf("\n");
                   2534:        fprintf(ficlog,"\n");
1.126     brouard  2535: #endif
1.192     brouard  2536:       } /* end of t or directest negative */
1.224     brouard  2537: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2538: #else
1.234     brouard  2539:       } /* end if (fptt < fp)  */
1.192     brouard  2540: #endif
1.225     brouard  2541: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2542:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2543: #else
1.224     brouard  2544: #endif
1.234     brouard  2545:                } /* loop iteration */ 
1.126     brouard  2546: } 
1.234     brouard  2547:   
1.126     brouard  2548: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2549:   
1.235     brouard  2550:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2551:   {
1.279     brouard  2552:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2553:      *   (and selected quantitative values in nres)
                   2554:      *  by left multiplying the unit
                   2555:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2556:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2557:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2558:      * or prevalence in state 1, prevalence in state 2, 0
                   2559:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2560:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2561:      * Output is prlim.
                   2562:      * Initial matrix pimij 
                   2563:      */
1.206     brouard  2564:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2565:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2566:   /*  0,                   0                  , 1} */
                   2567:   /*
                   2568:    * and after some iteration: */
                   2569:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2570:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2571:   /*  0,                   0                  , 1} */
                   2572:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2573:   /* {0.51571254859325999, 0.4842874514067399, */
                   2574:   /*  0.51326036147820708, 0.48673963852179264} */
                   2575:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2576:     
1.126     brouard  2577:   int i, ii,j,k;
1.209     brouard  2578:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2579:   /* double **matprod2(); */ /* test */
1.218     brouard  2580:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2581:   double **newm;
1.209     brouard  2582:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2583:   int ncvloop=0;
1.288     brouard  2584:   int first=0;
1.169     brouard  2585:   
1.209     brouard  2586:   min=vector(1,nlstate);
                   2587:   max=vector(1,nlstate);
                   2588:   meandiff=vector(1,nlstate);
                   2589: 
1.218     brouard  2590:        /* Starting with matrix unity */
1.126     brouard  2591:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2592:     for (j=1;j<=nlstate+ndeath;j++){
                   2593:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2594:     }
1.169     brouard  2595:   
                   2596:   cov[1]=1.;
                   2597:   
                   2598:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2599:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2600:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2601:     ncvloop++;
1.126     brouard  2602:     newm=savm;
                   2603:     /* Covariates have to be included here again */
1.138     brouard  2604:     cov[2]=agefin;
1.187     brouard  2605:     if(nagesqr==1)
                   2606:       cov[3]= agefin*agefin;;
1.234     brouard  2607:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2608:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2609:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2610:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2611:     }
                   2612:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2613:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2614:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2615:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2616:     }
1.237     brouard  2617:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2618:       if(Dummy[Tvar[Tage[k]]]){
                   2619:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2620:       } else{
1.235     brouard  2621:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2622:       }
1.235     brouard  2623:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2624:     }
1.237     brouard  2625:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2626:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2627:       if(Dummy[Tvard[k][1]==0]){
                   2628:        if(Dummy[Tvard[k][2]==0]){
                   2629:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2630:        }else{
                   2631:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2632:        }
                   2633:       }else{
                   2634:        if(Dummy[Tvard[k][2]==0]){
                   2635:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2636:        }else{
                   2637:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2638:        }
                   2639:       }
1.234     brouard  2640:     }
1.138     brouard  2641:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2642:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2643:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2644:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2645:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2646:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2647:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2648:     
1.126     brouard  2649:     savm=oldm;
                   2650:     oldm=newm;
1.209     brouard  2651: 
                   2652:     for(j=1; j<=nlstate; j++){
                   2653:       max[j]=0.;
                   2654:       min[j]=1.;
                   2655:     }
                   2656:     for(i=1;i<=nlstate;i++){
                   2657:       sumnew=0;
                   2658:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2659:       for(j=1; j<=nlstate; j++){ 
                   2660:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2661:        max[j]=FMAX(max[j],prlim[i][j]);
                   2662:        min[j]=FMIN(min[j],prlim[i][j]);
                   2663:       }
                   2664:     }
                   2665: 
1.126     brouard  2666:     maxmax=0.;
1.209     brouard  2667:     for(j=1; j<=nlstate; j++){
                   2668:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2669:       maxmax=FMAX(maxmax,meandiff[j]);
                   2670:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2671:     } /* j loop */
1.203     brouard  2672:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2673:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2674:     if(maxmax < ftolpl){
1.209     brouard  2675:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2676:       free_vector(min,1,nlstate);
                   2677:       free_vector(max,1,nlstate);
                   2678:       free_vector(meandiff,1,nlstate);
1.126     brouard  2679:       return prlim;
                   2680:     }
1.288     brouard  2681:   } /* agefin loop */
1.208     brouard  2682:     /* After some age loop it doesn't converge */
1.288     brouard  2683:   if(!first){
                   2684:     first=1;
                   2685:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2686:   }
                   2687:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2688: 
1.209     brouard  2689:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2690:   free_vector(min,1,nlstate);
                   2691:   free_vector(max,1,nlstate);
                   2692:   free_vector(meandiff,1,nlstate);
1.208     brouard  2693:   
1.169     brouard  2694:   return prlim; /* should not reach here */
1.126     brouard  2695: }
                   2696: 
1.217     brouard  2697: 
                   2698:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2699: 
1.218     brouard  2700:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2701:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2702:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2703: {
1.264     brouard  2704:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2705:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2706:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2707:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2708:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2709:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2710:   /* Initial matrix pimij */
                   2711:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2712:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2713:   /*  0,                   0                  , 1} */
                   2714:   /*
                   2715:    * and after some iteration: */
                   2716:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2717:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2718:   /*  0,                   0                  , 1} */
                   2719:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2720:   /* {0.51571254859325999, 0.4842874514067399, */
                   2721:   /*  0.51326036147820708, 0.48673963852179264} */
                   2722:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2723: 
                   2724:   int i, ii,j,k;
1.247     brouard  2725:   int first=0;
1.217     brouard  2726:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2727:   /* double **matprod2(); */ /* test */
                   2728:   double **out, cov[NCOVMAX+1], **bmij();
                   2729:   double **newm;
1.218     brouard  2730:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2731:   double        **oldm, **savm;  /* for use */
                   2732: 
1.217     brouard  2733:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2734:   int ncvloop=0;
                   2735:   
                   2736:   min=vector(1,nlstate);
                   2737:   max=vector(1,nlstate);
                   2738:   meandiff=vector(1,nlstate);
                   2739: 
1.266     brouard  2740:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2741:   oldm=oldms; savm=savms;
                   2742:   
                   2743:   /* Starting with matrix unity */
                   2744:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2745:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2746:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2747:     }
                   2748:   
                   2749:   cov[1]=1.;
                   2750:   
                   2751:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2752:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2753:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2754:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2755:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2756:     ncvloop++;
1.218     brouard  2757:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2758:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2759:     /* Covariates have to be included here again */
                   2760:     cov[2]=agefin;
                   2761:     if(nagesqr==1)
                   2762:       cov[3]= agefin*agefin;;
1.242     brouard  2763:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2764:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2765:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2766:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2767:     }
                   2768:     /* for (k=1; k<=cptcovn;k++) { */
                   2769:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2770:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2771:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2772:     /* } */
                   2773:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2774:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2775:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2776:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2777:     }
                   2778:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2779:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2780:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2781:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2782:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2783:       if(Dummy[Tvar[Tage[k]]]){
                   2784:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2785:       } else{
                   2786:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2787:       }
                   2788:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2789:     }
                   2790:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2791:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2792:       if(Dummy[Tvard[k][1]==0]){
                   2793:        if(Dummy[Tvard[k][2]==0]){
                   2794:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2795:        }else{
                   2796:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2797:        }
                   2798:       }else{
                   2799:        if(Dummy[Tvard[k][2]==0]){
                   2800:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2801:        }else{
                   2802:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2803:        }
                   2804:       }
1.217     brouard  2805:     }
                   2806:     
                   2807:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2808:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2809:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2810:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2811:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2812:                /* ij should be linked to the correct index of cov */
                   2813:                /* age and covariate values ij are in 'cov', but we need to pass
                   2814:                 * ij for the observed prevalence at age and status and covariate
                   2815:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2816:                 */
                   2817:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2818:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2819:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2820:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2821:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2822:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2823:     /*         printf("%d newm= ",i); */
                   2824:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2825:     /*           printf("%f ",newm[i][j]); */
                   2826:     /*         } */
                   2827:     /*         printf("oldm * "); */
                   2828:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2829:     /*           printf("%f ",oldm[i][j]); */
                   2830:     /*         } */
1.268     brouard  2831:     /*         printf(" bmmij "); */
1.266     brouard  2832:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2833:     /*           printf("%f ",pmmij[i][j]); */
                   2834:     /*         } */
                   2835:     /*         printf("\n"); */
                   2836:     /*   } */
                   2837:     /* } */
1.217     brouard  2838:     savm=oldm;
                   2839:     oldm=newm;
1.266     brouard  2840: 
1.217     brouard  2841:     for(j=1; j<=nlstate; j++){
                   2842:       max[j]=0.;
                   2843:       min[j]=1.;
                   2844:     }
                   2845:     for(j=1; j<=nlstate; j++){ 
                   2846:       for(i=1;i<=nlstate;i++){
1.234     brouard  2847:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2848:        bprlim[i][j]= newm[i][j];
                   2849:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2850:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2851:       }
                   2852:     }
1.218     brouard  2853:                
1.217     brouard  2854:     maxmax=0.;
                   2855:     for(i=1; i<=nlstate; i++){
                   2856:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2857:       maxmax=FMAX(maxmax,meandiff[i]);
                   2858:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2859:     } /* i loop */
1.217     brouard  2860:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2861:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2862:     if(maxmax < ftolpl){
1.220     brouard  2863:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2864:       free_vector(min,1,nlstate);
                   2865:       free_vector(max,1,nlstate);
                   2866:       free_vector(meandiff,1,nlstate);
                   2867:       return bprlim;
                   2868:     }
1.288     brouard  2869:   } /* agefin loop */
1.217     brouard  2870:     /* After some age loop it doesn't converge */
1.288     brouard  2871:   if(!first){
1.247     brouard  2872:     first=1;
                   2873:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2874: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2875:   }
                   2876:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2877: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2878:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2879:   free_vector(min,1,nlstate);
                   2880:   free_vector(max,1,nlstate);
                   2881:   free_vector(meandiff,1,nlstate);
                   2882:   
                   2883:   return bprlim; /* should not reach here */
                   2884: }
                   2885: 
1.126     brouard  2886: /*************** transition probabilities ***************/ 
                   2887: 
                   2888: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2889: {
1.138     brouard  2890:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2891:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2892:      model to the ncovmodel covariates (including constant and age).
                   2893:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2894:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2895:      ncth covariate in the global vector x is given by the formula:
                   2896:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2897:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2898:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2899:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2900:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2901:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2902:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2903:   */
                   2904:   double s1, lnpijopii;
1.126     brouard  2905:   /*double t34;*/
1.164     brouard  2906:   int i,j, nc, ii, jj;
1.126     brouard  2907: 
1.223     brouard  2908:   for(i=1; i<= nlstate; i++){
                   2909:     for(j=1; j<i;j++){
                   2910:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2911:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2912:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2913:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2914:       }
                   2915:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2916:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2917:     }
                   2918:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2919:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2920:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2921:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2922:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2923:       }
                   2924:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2925:     }
                   2926:   }
1.218     brouard  2927:   
1.223     brouard  2928:   for(i=1; i<= nlstate; i++){
                   2929:     s1=0;
                   2930:     for(j=1; j<i; j++){
                   2931:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2932:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2933:     }
                   2934:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2935:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2936:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2937:     }
                   2938:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2939:     ps[i][i]=1./(s1+1.);
                   2940:     /* Computing other pijs */
                   2941:     for(j=1; j<i; j++)
                   2942:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2943:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2944:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2945:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2946:   } /* end i */
1.218     brouard  2947:   
1.223     brouard  2948:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2949:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2950:       ps[ii][jj]=0;
                   2951:       ps[ii][ii]=1;
                   2952:     }
                   2953:   }
1.218     brouard  2954:   
                   2955:   
1.223     brouard  2956:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2957:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2958:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2959:   /*   } */
                   2960:   /*   printf("\n "); */
                   2961:   /* } */
                   2962:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2963:   /*
                   2964:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2965:                goto end;*/
1.266     brouard  2966:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2967: }
                   2968: 
1.218     brouard  2969: /*************** backward transition probabilities ***************/ 
                   2970: 
                   2971:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2972: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2973:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2974: {
1.266     brouard  2975:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2976:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2977:    */
1.218     brouard  2978:   int i, ii, j,k;
1.222     brouard  2979:   
                   2980:   double **out, **pmij();
                   2981:   double sumnew=0.;
1.218     brouard  2982:   double agefin;
1.268     brouard  2983:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2984:   double **dnewm, **dsavm, **doldm;
                   2985:   double **bbmij;
                   2986:   
1.218     brouard  2987:   doldm=ddoldms; /* global pointers */
1.222     brouard  2988:   dnewm=ddnewms;
                   2989:   dsavm=ddsavms;
                   2990:   
                   2991:   agefin=cov[2];
1.268     brouard  2992:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  2993:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  2994:      the observed prevalence (with this covariate ij) at beginning of transition */
                   2995:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  2996: 
                   2997:   /* P_x */
1.266     brouard  2998:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  2999:   /* outputs pmmij which is a stochastic matrix in row */
                   3000: 
                   3001:   /* Diag(w_x) */
                   3002:   /* Problem with prevacurrent which can be zero */
                   3003:   sumnew=0.;
1.269     brouard  3004:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3005:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  3006:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  3007:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3008:   }
                   3009:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3010:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3011:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3012:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3013:     }
                   3014:   }else{
                   3015:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3016:       for (j=1;j<=nlstate+ndeath;j++)
                   3017:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3018:     }
                   3019:     /* if(sumnew <0.9){ */
                   3020:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3021:     /* } */
                   3022:   }
                   3023:   k3=0.0;  /* We put the last diagonal to 0 */
                   3024:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3025:       doldm[ii][ii]= k3;
                   3026:   }
                   3027:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3028:   
                   3029:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   3030:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   3031: 
                   3032:   /* Diag(Sum_i w^i_x p^ij_x */
                   3033:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3034:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3035:     sumnew=0.;
1.222     brouard  3036:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3037:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3038:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3039:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3040:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3041:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3042:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3043:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3044:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3045:        /* }else */
1.268     brouard  3046:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3047:     } /*End ii */
                   3048:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3049: 
                   3050:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   3051:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3052:   /* end bmij */
1.266     brouard  3053:   return ps; /*pointer is unchanged */
1.218     brouard  3054: }
1.217     brouard  3055: /*************** transition probabilities ***************/ 
                   3056: 
1.218     brouard  3057: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3058: {
                   3059:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3060:      computes the probability to be observed in state j being in state i by appying the
                   3061:      model to the ncovmodel covariates (including constant and age).
                   3062:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3063:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3064:      ncth covariate in the global vector x is given by the formula:
                   3065:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3066:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3067:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3068:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3069:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3070:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3071:   */
                   3072:   double s1, lnpijopii;
                   3073:   /*double t34;*/
                   3074:   int i,j, nc, ii, jj;
                   3075: 
1.234     brouard  3076:   for(i=1; i<= nlstate; i++){
                   3077:     for(j=1; j<i;j++){
                   3078:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3079:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3080:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3081:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3082:       }
                   3083:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3084:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3085:     }
                   3086:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3087:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3088:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3089:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3090:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3091:       }
                   3092:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3093:     }
                   3094:   }
                   3095:   
                   3096:   for(i=1; i<= nlstate; i++){
                   3097:     s1=0;
                   3098:     for(j=1; j<i; j++){
                   3099:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3100:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3101:     }
                   3102:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3103:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3104:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3105:     }
                   3106:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3107:     ps[i][i]=1./(s1+1.);
                   3108:     /* Computing other pijs */
                   3109:     for(j=1; j<i; j++)
                   3110:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3111:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3112:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3113:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3114:   } /* end i */
                   3115:   
                   3116:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3117:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3118:       ps[ii][jj]=0;
                   3119:       ps[ii][ii]=1;
                   3120:     }
                   3121:   }
                   3122:   /* Added for backcast */ /* Transposed matrix too */
                   3123:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3124:     s1=0.;
                   3125:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3126:       s1+=ps[ii][jj];
                   3127:     }
                   3128:     for(ii=1; ii<= nlstate; ii++){
                   3129:       ps[ii][jj]=ps[ii][jj]/s1;
                   3130:     }
                   3131:   }
                   3132:   /* Transposition */
                   3133:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3134:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3135:       s1=ps[ii][jj];
                   3136:       ps[ii][jj]=ps[jj][ii];
                   3137:       ps[jj][ii]=s1;
                   3138:     }
                   3139:   }
                   3140:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3141:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3142:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3143:   /*   } */
                   3144:   /*   printf("\n "); */
                   3145:   /* } */
                   3146:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3147:   /*
                   3148:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3149:     goto end;*/
                   3150:   return ps;
1.217     brouard  3151: }
                   3152: 
                   3153: 
1.126     brouard  3154: /**************** Product of 2 matrices ******************/
                   3155: 
1.145     brouard  3156: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3157: {
                   3158:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3159:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3160:   /* in, b, out are matrice of pointers which should have been initialized 
                   3161:      before: only the contents of out is modified. The function returns
                   3162:      a pointer to pointers identical to out */
1.145     brouard  3163:   int i, j, k;
1.126     brouard  3164:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3165:     for(k=ncolol; k<=ncoloh; k++){
                   3166:       out[i][k]=0.;
                   3167:       for(j=ncl; j<=nch; j++)
                   3168:        out[i][k] +=in[i][j]*b[j][k];
                   3169:     }
1.126     brouard  3170:   return out;
                   3171: }
                   3172: 
                   3173: 
                   3174: /************* Higher Matrix Product ***************/
                   3175: 
1.235     brouard  3176: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3177: {
1.218     brouard  3178:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3179:      'nhstepm*hstepm*stepm' months (i.e. until
                   3180:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3181:      nhstepm*hstepm matrices. 
                   3182:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3183:      (typically every 2 years instead of every month which is too big 
                   3184:      for the memory).
                   3185:      Model is determined by parameters x and covariates have to be 
                   3186:      included manually here. 
                   3187: 
                   3188:      */
                   3189: 
                   3190:   int i, j, d, h, k;
1.131     brouard  3191:   double **out, cov[NCOVMAX+1];
1.126     brouard  3192:   double **newm;
1.187     brouard  3193:   double agexact;
1.214     brouard  3194:   double agebegin, ageend;
1.126     brouard  3195: 
                   3196:   /* Hstepm could be zero and should return the unit matrix */
                   3197:   for (i=1;i<=nlstate+ndeath;i++)
                   3198:     for (j=1;j<=nlstate+ndeath;j++){
                   3199:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3200:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3201:     }
                   3202:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3203:   for(h=1; h <=nhstepm; h++){
                   3204:     for(d=1; d <=hstepm; d++){
                   3205:       newm=savm;
                   3206:       /* Covariates have to be included here again */
                   3207:       cov[1]=1.;
1.214     brouard  3208:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3209:       cov[2]=agexact;
                   3210:       if(nagesqr==1)
1.227     brouard  3211:        cov[3]= agexact*agexact;
1.235     brouard  3212:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3213:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3214:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3215:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3216:       }
                   3217:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3218:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3219:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3220:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3221:       }
                   3222:       for (k=1; k<=cptcovage;k++){
                   3223:        if(Dummy[Tvar[Tage[k]]]){
                   3224:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3225:        } else{
                   3226:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3227:        }
                   3228:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3229:       }
                   3230:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3231:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3232:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3233:       }
                   3234:       /* for (k=1; k<=cptcovn;k++)  */
                   3235:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3236:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3237:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3238:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3239:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3240:       
                   3241:       
1.126     brouard  3242:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3243:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3244:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3245:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3246:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3247:       /* if((int)age == 70){ */
                   3248:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3249:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3250:       /*         printf("%d pmmij ",i); */
                   3251:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3252:       /*           printf("%f ",pmmij[i][j]); */
                   3253:       /*         } */
                   3254:       /*         printf(" oldm "); */
                   3255:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3256:       /*           printf("%f ",oldm[i][j]); */
                   3257:       /*         } */
                   3258:       /*         printf("\n"); */
                   3259:       /*       } */
                   3260:       /* } */
1.126     brouard  3261:       savm=oldm;
                   3262:       oldm=newm;
                   3263:     }
                   3264:     for(i=1; i<=nlstate+ndeath; i++)
                   3265:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3266:        po[i][j][h]=newm[i][j];
                   3267:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3268:       }
1.128     brouard  3269:     /*printf("h=%d ",h);*/
1.126     brouard  3270:   } /* end h */
1.267     brouard  3271:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3272:   return po;
                   3273: }
                   3274: 
1.217     brouard  3275: /************* Higher Back Matrix Product ***************/
1.218     brouard  3276: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3277: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3278: {
1.266     brouard  3279:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3280:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3281:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3282:      nhstepm*hstepm matrices.
                   3283:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3284:      (typically every 2 years instead of every month which is too big
1.217     brouard  3285:      for the memory).
1.218     brouard  3286:      Model is determined by parameters x and covariates have to be
1.266     brouard  3287:      included manually here. Then we use a call to bmij(x and cov)
                   3288:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3289:   */
1.217     brouard  3290: 
                   3291:   int i, j, d, h, k;
1.266     brouard  3292:   double **out, cov[NCOVMAX+1], **bmij();
                   3293:   double **newm, ***newmm;
1.217     brouard  3294:   double agexact;
                   3295:   double agebegin, ageend;
1.222     brouard  3296:   double **oldm, **savm;
1.217     brouard  3297: 
1.266     brouard  3298:   newmm=po; /* To be saved */
                   3299:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3300:   /* Hstepm could be zero and should return the unit matrix */
                   3301:   for (i=1;i<=nlstate+ndeath;i++)
                   3302:     for (j=1;j<=nlstate+ndeath;j++){
                   3303:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3304:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3305:     }
                   3306:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3307:   for(h=1; h <=nhstepm; h++){
                   3308:     for(d=1; d <=hstepm; d++){
                   3309:       newm=savm;
                   3310:       /* Covariates have to be included here again */
                   3311:       cov[1]=1.;
1.271     brouard  3312:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3313:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3314:       cov[2]=agexact;
                   3315:       if(nagesqr==1)
1.222     brouard  3316:        cov[3]= agexact*agexact;
1.266     brouard  3317:       for (k=1; k<=cptcovn;k++){
                   3318:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3319:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3320:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3321:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3322:       }
1.267     brouard  3323:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3324:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3325:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3326:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3327:       }
                   3328:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3329:        if(Dummy[Tvar[Tage[k]]]){
                   3330:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3331:        } else{
                   3332:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3333:        }
                   3334:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3335:       }
                   3336:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3337:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3338:       }                        
1.217     brouard  3339:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3340:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3341: 
1.218     brouard  3342:       /* Careful transposed matrix */
1.266     brouard  3343:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3344:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3345:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3346:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3347:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3348:       /* if((int)age == 70){ */
                   3349:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3350:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3351:       /*         printf("%d pmmij ",i); */
                   3352:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3353:       /*           printf("%f ",pmmij[i][j]); */
                   3354:       /*         } */
                   3355:       /*         printf(" oldm "); */
                   3356:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3357:       /*           printf("%f ",oldm[i][j]); */
                   3358:       /*         } */
                   3359:       /*         printf("\n"); */
                   3360:       /*       } */
                   3361:       /* } */
                   3362:       savm=oldm;
                   3363:       oldm=newm;
                   3364:     }
                   3365:     for(i=1; i<=nlstate+ndeath; i++)
                   3366:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3367:        po[i][j][h]=newm[i][j];
1.268     brouard  3368:        /* if(h==nhstepm) */
                   3369:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3370:       }
1.268     brouard  3371:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3372:   } /* end h */
1.268     brouard  3373:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3374:   return po;
                   3375: }
                   3376: 
                   3377: 
1.162     brouard  3378: #ifdef NLOPT
                   3379:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3380:   double fret;
                   3381:   double *xt;
                   3382:   int j;
                   3383:   myfunc_data *d2 = (myfunc_data *) pd;
                   3384: /* xt = (p1-1); */
                   3385:   xt=vector(1,n); 
                   3386:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3387: 
                   3388:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3389:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3390:   printf("Function = %.12lf ",fret);
                   3391:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3392:   printf("\n");
                   3393:  free_vector(xt,1,n);
                   3394:   return fret;
                   3395: }
                   3396: #endif
1.126     brouard  3397: 
                   3398: /*************** log-likelihood *************/
                   3399: double func( double *x)
                   3400: {
1.226     brouard  3401:   int i, ii, j, k, mi, d, kk;
                   3402:   int ioffset=0;
                   3403:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3404:   double **out;
                   3405:   double lli; /* Individual log likelihood */
                   3406:   int s1, s2;
1.228     brouard  3407:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3408:   double bbh, survp;
                   3409:   long ipmx;
                   3410:   double agexact;
                   3411:   /*extern weight */
                   3412:   /* We are differentiating ll according to initial status */
                   3413:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3414:   /*for(i=1;i<imx;i++) 
                   3415:     printf(" %d\n",s[4][i]);
                   3416:   */
1.162     brouard  3417: 
1.226     brouard  3418:   ++countcallfunc;
1.162     brouard  3419: 
1.226     brouard  3420:   cov[1]=1.;
1.126     brouard  3421: 
1.226     brouard  3422:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3423:   ioffset=0;
1.226     brouard  3424:   if(mle==1){
                   3425:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3426:       /* Computes the values of the ncovmodel covariates of the model
                   3427:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3428:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3429:         to be observed in j being in i according to the model.
                   3430:       */
1.243     brouard  3431:       ioffset=2+nagesqr ;
1.233     brouard  3432:    /* Fixed */
1.234     brouard  3433:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3434:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3435:       }
1.226     brouard  3436:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3437:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3438:         has been calculated etc */
                   3439:       /* For an individual i, wav[i] gives the number of effective waves */
                   3440:       /* We compute the contribution to Likelihood of each effective transition
                   3441:         mw[mi][i] is real wave of the mi th effectve wave */
                   3442:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3443:         s2=s[mw[mi+1][i]][i];
                   3444:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3445:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3446:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3447:       */
                   3448:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3449:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3450:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3451:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3452:        }
                   3453:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3454:          for (j=1;j<=nlstate+ndeath;j++){
                   3455:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3456:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3457:          }
                   3458:        for(d=0; d<dh[mi][i]; d++){
                   3459:          newm=savm;
                   3460:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3461:          cov[2]=agexact;
                   3462:          if(nagesqr==1)
                   3463:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3464:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3465:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3466:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3467:          else
                   3468:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3469:          }
                   3470:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3471:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3472:          savm=oldm;
                   3473:          oldm=newm;
                   3474:        } /* end mult */
                   3475:        
                   3476:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3477:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3478:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3479:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3480:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3481:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3482:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3483:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3484:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3485:                                 * -stepm/2 to stepm/2 .
                   3486:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3487:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3488:                                 */
1.234     brouard  3489:        s1=s[mw[mi][i]][i];
                   3490:        s2=s[mw[mi+1][i]][i];
                   3491:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3492:        /* bias bh is positive if real duration
                   3493:         * is higher than the multiple of stepm and negative otherwise.
                   3494:         */
                   3495:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3496:        if( s2 > nlstate){ 
                   3497:          /* i.e. if s2 is a death state and if the date of death is known 
                   3498:             then the contribution to the likelihood is the probability to 
                   3499:             die between last step unit time and current  step unit time, 
                   3500:             which is also equal to probability to die before dh 
                   3501:             minus probability to die before dh-stepm . 
                   3502:             In version up to 0.92 likelihood was computed
                   3503:             as if date of death was unknown. Death was treated as any other
                   3504:             health state: the date of the interview describes the actual state
                   3505:             and not the date of a change in health state. The former idea was
                   3506:             to consider that at each interview the state was recorded
                   3507:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3508:             introduced the exact date of death then we should have modified
                   3509:             the contribution of an exact death to the likelihood. This new
                   3510:             contribution is smaller and very dependent of the step unit
                   3511:             stepm. It is no more the probability to die between last interview
                   3512:             and month of death but the probability to survive from last
                   3513:             interview up to one month before death multiplied by the
                   3514:             probability to die within a month. Thanks to Chris
                   3515:             Jackson for correcting this bug.  Former versions increased
                   3516:             mortality artificially. The bad side is that we add another loop
                   3517:             which slows down the processing. The difference can be up to 10%
                   3518:             lower mortality.
                   3519:          */
                   3520:          /* If, at the beginning of the maximization mostly, the
                   3521:             cumulative probability or probability to be dead is
                   3522:             constant (ie = 1) over time d, the difference is equal to
                   3523:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3524:             s1 at precedent wave, to be dead a month before current
                   3525:             wave is equal to probability, being at state s1 at
                   3526:             precedent wave, to be dead at mont of the current
                   3527:             wave. Then the observed probability (that this person died)
                   3528:             is null according to current estimated parameter. In fact,
                   3529:             it should be very low but not zero otherwise the log go to
                   3530:             infinity.
                   3531:          */
1.183     brouard  3532: /* #ifdef INFINITYORIGINAL */
                   3533: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3534: /* #else */
                   3535: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3536: /*         lli=log(mytinydouble); */
                   3537: /*       else */
                   3538: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3539: /* #endif */
1.226     brouard  3540:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3541:          
1.226     brouard  3542:        } else if  ( s2==-1 ) { /* alive */
                   3543:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3544:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3545:          /*survp += out[s1][j]; */
                   3546:          lli= log(survp);
                   3547:        }
                   3548:        else if  (s2==-4) { 
                   3549:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3550:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3551:          lli= log(survp); 
                   3552:        } 
                   3553:        else if  (s2==-5) { 
                   3554:          for (j=1,survp=0. ; j<=2; j++)  
                   3555:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3556:          lli= log(survp); 
                   3557:        } 
                   3558:        else{
                   3559:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3560:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3561:        } 
                   3562:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3563:        /*if(lli ==000.0)*/
                   3564:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3565:        ipmx +=1;
                   3566:        sw += weight[i];
                   3567:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3568:        /* if (lli < log(mytinydouble)){ */
                   3569:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3570:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3571:        /* } */
                   3572:       } /* end of wave */
                   3573:     } /* end of individual */
                   3574:   }  else if(mle==2){
                   3575:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3576:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3577:       for(mi=1; mi<= wav[i]-1; mi++){
                   3578:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3579:          for (j=1;j<=nlstate+ndeath;j++){
                   3580:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3581:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3582:          }
                   3583:        for(d=0; d<=dh[mi][i]; d++){
                   3584:          newm=savm;
                   3585:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3586:          cov[2]=agexact;
                   3587:          if(nagesqr==1)
                   3588:            cov[3]= agexact*agexact;
                   3589:          for (kk=1; kk<=cptcovage;kk++) {
                   3590:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3591:          }
                   3592:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3593:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3594:          savm=oldm;
                   3595:          oldm=newm;
                   3596:        } /* end mult */
                   3597:       
                   3598:        s1=s[mw[mi][i]][i];
                   3599:        s2=s[mw[mi+1][i]][i];
                   3600:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3601:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3602:        ipmx +=1;
                   3603:        sw += weight[i];
                   3604:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3605:       } /* end of wave */
                   3606:     } /* end of individual */
                   3607:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3608:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3609:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3610:       for(mi=1; mi<= wav[i]-1; mi++){
                   3611:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3612:          for (j=1;j<=nlstate+ndeath;j++){
                   3613:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3614:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3615:          }
                   3616:        for(d=0; d<dh[mi][i]; d++){
                   3617:          newm=savm;
                   3618:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3619:          cov[2]=agexact;
                   3620:          if(nagesqr==1)
                   3621:            cov[3]= agexact*agexact;
                   3622:          for (kk=1; kk<=cptcovage;kk++) {
                   3623:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3624:          }
                   3625:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3626:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3627:          savm=oldm;
                   3628:          oldm=newm;
                   3629:        } /* end mult */
                   3630:       
                   3631:        s1=s[mw[mi][i]][i];
                   3632:        s2=s[mw[mi+1][i]][i];
                   3633:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3634:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3635:        ipmx +=1;
                   3636:        sw += weight[i];
                   3637:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3638:       } /* end of wave */
                   3639:     } /* end of individual */
                   3640:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3641:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3642:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3643:       for(mi=1; mi<= wav[i]-1; mi++){
                   3644:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3645:          for (j=1;j<=nlstate+ndeath;j++){
                   3646:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3647:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3648:          }
                   3649:        for(d=0; d<dh[mi][i]; d++){
                   3650:          newm=savm;
                   3651:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3652:          cov[2]=agexact;
                   3653:          if(nagesqr==1)
                   3654:            cov[3]= agexact*agexact;
                   3655:          for (kk=1; kk<=cptcovage;kk++) {
                   3656:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3657:          }
1.126     brouard  3658:        
1.226     brouard  3659:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3660:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3661:          savm=oldm;
                   3662:          oldm=newm;
                   3663:        } /* end mult */
                   3664:       
                   3665:        s1=s[mw[mi][i]][i];
                   3666:        s2=s[mw[mi+1][i]][i];
                   3667:        if( s2 > nlstate){ 
                   3668:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3669:        } else if  ( s2==-1 ) { /* alive */
                   3670:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3671:            survp += out[s1][j];
                   3672:          lli= log(survp);
                   3673:        }else{
                   3674:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3675:        }
                   3676:        ipmx +=1;
                   3677:        sw += weight[i];
                   3678:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3679: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3680:       } /* end of wave */
                   3681:     } /* end of individual */
                   3682:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3683:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3684:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3685:       for(mi=1; mi<= wav[i]-1; mi++){
                   3686:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3687:          for (j=1;j<=nlstate+ndeath;j++){
                   3688:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3689:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3690:          }
                   3691:        for(d=0; d<dh[mi][i]; d++){
                   3692:          newm=savm;
                   3693:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3694:          cov[2]=agexact;
                   3695:          if(nagesqr==1)
                   3696:            cov[3]= agexact*agexact;
                   3697:          for (kk=1; kk<=cptcovage;kk++) {
                   3698:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3699:          }
1.126     brouard  3700:        
1.226     brouard  3701:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3702:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3703:          savm=oldm;
                   3704:          oldm=newm;
                   3705:        } /* end mult */
                   3706:       
                   3707:        s1=s[mw[mi][i]][i];
                   3708:        s2=s[mw[mi+1][i]][i];
                   3709:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3710:        ipmx +=1;
                   3711:        sw += weight[i];
                   3712:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3713:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3714:       } /* end of wave */
                   3715:     } /* end of individual */
                   3716:   } /* End of if */
                   3717:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3718:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3719:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3720:   return -l;
1.126     brouard  3721: }
                   3722: 
                   3723: /*************** log-likelihood *************/
                   3724: double funcone( double *x)
                   3725: {
1.228     brouard  3726:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3727:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3728:   int ioffset=0;
1.131     brouard  3729:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3730:   double **out;
                   3731:   double lli; /* Individual log likelihood */
                   3732:   double llt;
                   3733:   int s1, s2;
1.228     brouard  3734:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3735: 
1.126     brouard  3736:   double bbh, survp;
1.187     brouard  3737:   double agexact;
1.214     brouard  3738:   double agebegin, ageend;
1.126     brouard  3739:   /*extern weight */
                   3740:   /* We are differentiating ll according to initial status */
                   3741:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3742:   /*for(i=1;i<imx;i++) 
                   3743:     printf(" %d\n",s[4][i]);
                   3744:   */
                   3745:   cov[1]=1.;
                   3746: 
                   3747:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3748:   ioffset=0;
                   3749:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3750:     /* ioffset=2+nagesqr+cptcovage; */
                   3751:     ioffset=2+nagesqr;
1.232     brouard  3752:     /* Fixed */
1.224     brouard  3753:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3754:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3755:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3756:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3757: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3758: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3759: /*    cov[2+6]=covar[2][i]; V2  */
                   3760: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3761: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3762: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3763: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3764: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3765: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3766:     }
1.232     brouard  3767:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3768:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3769:     /* } */
1.231     brouard  3770:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3771:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3772:     /* } */
1.225     brouard  3773:     
1.233     brouard  3774: 
                   3775:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3776:     /* Wave varying (but not age varying) */
                   3777:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3778:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3779:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3780:       }
1.232     brouard  3781:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3782:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3783:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3784:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3785:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3786:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3787:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3788:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3789:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3790:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3791:       /* } */
1.126     brouard  3792:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3793:        for (j=1;j<=nlstate+ndeath;j++){
                   3794:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3795:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3796:        }
1.214     brouard  3797:       
                   3798:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3799:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3800:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3801:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3802:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3803:          and mw[mi+1][i]. dh depends on stepm.*/
                   3804:        newm=savm;
1.247     brouard  3805:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3806:        cov[2]=agexact;
                   3807:        if(nagesqr==1)
                   3808:          cov[3]= agexact*agexact;
                   3809:        for (kk=1; kk<=cptcovage;kk++) {
                   3810:          if(!FixedV[Tvar[Tage[kk]]])
                   3811:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3812:          else
                   3813:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3814:        }
                   3815:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3816:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3817:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3818:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3819:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3820:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3821:        savm=oldm;
                   3822:        oldm=newm;
1.126     brouard  3823:       } /* end mult */
                   3824:       
                   3825:       s1=s[mw[mi][i]][i];
                   3826:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3827:       /* if(s2==-1){ */
1.268     brouard  3828:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3829:       /*       /\* exit(1); *\/ */
                   3830:       /* } */
1.126     brouard  3831:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3832:       /* bias is positive if real duration
                   3833:        * is higher than the multiple of stepm and negative otherwise.
                   3834:        */
                   3835:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3836:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3837:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3838:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3839:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3840:        lli= log(survp);
1.126     brouard  3841:       }else if (mle==1){
1.242     brouard  3842:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3843:       } else if(mle==2){
1.242     brouard  3844:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3845:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3846:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3847:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3848:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3849:       } else{  /* mle=0 back to 1 */
1.242     brouard  3850:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3851:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3852:       } /* End of if */
                   3853:       ipmx +=1;
                   3854:       sw += weight[i];
                   3855:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3856:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3857:       if(globpr){
1.246     brouard  3858:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3859:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3860:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3861:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3862:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3863:          llt +=ll[k]*gipmx/gsw;
                   3864:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3865:        }
                   3866:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3867:       }
1.232     brouard  3868:        } /* end of wave */
                   3869: } /* end of individual */
                   3870: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3871: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3872: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3873: if(globpr==0){ /* First time we count the contributions and weights */
                   3874:        gipmx=ipmx;
                   3875:        gsw=sw;
                   3876: }
                   3877: return -l;
1.126     brouard  3878: }
                   3879: 
                   3880: 
                   3881: /*************** function likelione ***********/
                   3882: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3883: {
                   3884:   /* This routine should help understanding what is done with 
                   3885:      the selection of individuals/waves and
                   3886:      to check the exact contribution to the likelihood.
                   3887:      Plotting could be done.
                   3888:    */
                   3889:   int k;
                   3890: 
                   3891:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3892:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3893:     strcat(fileresilk,fileresu);
1.126     brouard  3894:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3895:       printf("Problem with resultfile: %s\n", fileresilk);
                   3896:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3897:     }
1.214     brouard  3898:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3899:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3900:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3901:     for(k=1; k<=nlstate; k++) 
                   3902:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3903:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3904:   }
                   3905: 
                   3906:   *fretone=(*funcone)(p);
                   3907:   if(*globpri !=0){
                   3908:     fclose(ficresilk);
1.205     brouard  3909:     if (mle ==0)
                   3910:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3911:     else if(mle >=1)
                   3912:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3913:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3914:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3915:       
                   3916:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3917:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3918: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3919:     }
1.207     brouard  3920:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3921: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3922:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3923: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3924:     fflush(fichtm);
1.205     brouard  3925:   }
1.126     brouard  3926:   return;
                   3927: }
                   3928: 
                   3929: 
                   3930: /*********** Maximum Likelihood Estimation ***************/
                   3931: 
                   3932: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3933: {
1.165     brouard  3934:   int i,j, iter=0;
1.126     brouard  3935:   double **xi;
                   3936:   double fret;
                   3937:   double fretone; /* Only one call to likelihood */
                   3938:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3939: 
                   3940: #ifdef NLOPT
                   3941:   int creturn;
                   3942:   nlopt_opt opt;
                   3943:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3944:   double *lb;
                   3945:   double minf; /* the minimum objective value, upon return */
                   3946:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3947:   myfunc_data dinst, *d = &dinst;
                   3948: #endif
                   3949: 
                   3950: 
1.126     brouard  3951:   xi=matrix(1,npar,1,npar);
                   3952:   for (i=1;i<=npar;i++)
                   3953:     for (j=1;j<=npar;j++)
                   3954:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3955:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3956:   strcpy(filerespow,"POW_"); 
1.126     brouard  3957:   strcat(filerespow,fileres);
                   3958:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3959:     printf("Problem with resultfile: %s\n", filerespow);
                   3960:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3961:   }
                   3962:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3963:   for (i=1;i<=nlstate;i++)
                   3964:     for(j=1;j<=nlstate+ndeath;j++)
                   3965:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3966:   fprintf(ficrespow,"\n");
1.162     brouard  3967: #ifdef POWELL
1.126     brouard  3968:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3969: #endif
1.126     brouard  3970: 
1.162     brouard  3971: #ifdef NLOPT
                   3972: #ifdef NEWUOA
                   3973:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3974: #else
                   3975:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3976: #endif
                   3977:   lb=vector(0,npar-1);
                   3978:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3979:   nlopt_set_lower_bounds(opt, lb);
                   3980:   nlopt_set_initial_step1(opt, 0.1);
                   3981:   
                   3982:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3983:   d->function = func;
                   3984:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3985:   nlopt_set_min_objective(opt, myfunc, d);
                   3986:   nlopt_set_xtol_rel(opt, ftol);
                   3987:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3988:     printf("nlopt failed! %d\n",creturn); 
                   3989:   }
                   3990:   else {
                   3991:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   3992:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   3993:     iter=1; /* not equal */
                   3994:   }
                   3995:   nlopt_destroy(opt);
                   3996: #endif
1.126     brouard  3997:   free_matrix(xi,1,npar,1,npar);
                   3998:   fclose(ficrespow);
1.203     brouard  3999:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4000:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4001:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4002: 
                   4003: }
                   4004: 
                   4005: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4006: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4007: {
                   4008:   double  **a,**y,*x,pd;
1.203     brouard  4009:   /* double **hess; */
1.164     brouard  4010:   int i, j;
1.126     brouard  4011:   int *indx;
                   4012: 
                   4013:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4014:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4015:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4016:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4017:   double gompertz(double p[]);
1.203     brouard  4018:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4019: 
                   4020:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4021:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4022:   for (i=1;i<=npar;i++){
1.203     brouard  4023:     printf("%d-",i);fflush(stdout);
                   4024:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4025:    
                   4026:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4027:     
                   4028:     /*  printf(" %f ",p[i]);
                   4029:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4030:   }
                   4031:   
                   4032:   for (i=1;i<=npar;i++) {
                   4033:     for (j=1;j<=npar;j++)  {
                   4034:       if (j>i) { 
1.203     brouard  4035:        printf(".%d-%d",i,j);fflush(stdout);
                   4036:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4037:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4038:        
                   4039:        hess[j][i]=hess[i][j];    
                   4040:        /*printf(" %lf ",hess[i][j]);*/
                   4041:       }
                   4042:     }
                   4043:   }
                   4044:   printf("\n");
                   4045:   fprintf(ficlog,"\n");
                   4046: 
                   4047:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4048:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4049:   
                   4050:   a=matrix(1,npar,1,npar);
                   4051:   y=matrix(1,npar,1,npar);
                   4052:   x=vector(1,npar);
                   4053:   indx=ivector(1,npar);
                   4054:   for (i=1;i<=npar;i++)
                   4055:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4056:   ludcmp(a,npar,indx,&pd);
                   4057: 
                   4058:   for (j=1;j<=npar;j++) {
                   4059:     for (i=1;i<=npar;i++) x[i]=0;
                   4060:     x[j]=1;
                   4061:     lubksb(a,npar,indx,x);
                   4062:     for (i=1;i<=npar;i++){ 
                   4063:       matcov[i][j]=x[i];
                   4064:     }
                   4065:   }
                   4066: 
                   4067:   printf("\n#Hessian matrix#\n");
                   4068:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4069:   for (i=1;i<=npar;i++) { 
                   4070:     for (j=1;j<=npar;j++) { 
1.203     brouard  4071:       printf("%.6e ",hess[i][j]);
                   4072:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4073:     }
                   4074:     printf("\n");
                   4075:     fprintf(ficlog,"\n");
                   4076:   }
                   4077: 
1.203     brouard  4078:   /* printf("\n#Covariance matrix#\n"); */
                   4079:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4080:   /* for (i=1;i<=npar;i++) {  */
                   4081:   /*   for (j=1;j<=npar;j++) {  */
                   4082:   /*     printf("%.6e ",matcov[i][j]); */
                   4083:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4084:   /*   } */
                   4085:   /*   printf("\n"); */
                   4086:   /*   fprintf(ficlog,"\n"); */
                   4087:   /* } */
                   4088: 
1.126     brouard  4089:   /* Recompute Inverse */
1.203     brouard  4090:   /* for (i=1;i<=npar;i++) */
                   4091:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4092:   /* ludcmp(a,npar,indx,&pd); */
                   4093: 
                   4094:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4095: 
                   4096:   /* for (j=1;j<=npar;j++) { */
                   4097:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4098:   /*   x[j]=1; */
                   4099:   /*   lubksb(a,npar,indx,x); */
                   4100:   /*   for (i=1;i<=npar;i++){  */
                   4101:   /*     y[i][j]=x[i]; */
                   4102:   /*     printf("%.3e ",y[i][j]); */
                   4103:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4104:   /*   } */
                   4105:   /*   printf("\n"); */
                   4106:   /*   fprintf(ficlog,"\n"); */
                   4107:   /* } */
                   4108: 
                   4109:   /* Verifying the inverse matrix */
                   4110: #ifdef DEBUGHESS
                   4111:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4112: 
1.203     brouard  4113:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4114:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4115: 
                   4116:   for (j=1;j<=npar;j++) {
                   4117:     for (i=1;i<=npar;i++){ 
1.203     brouard  4118:       printf("%.2f ",y[i][j]);
                   4119:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4120:     }
                   4121:     printf("\n");
                   4122:     fprintf(ficlog,"\n");
                   4123:   }
1.203     brouard  4124: #endif
1.126     brouard  4125: 
                   4126:   free_matrix(a,1,npar,1,npar);
                   4127:   free_matrix(y,1,npar,1,npar);
                   4128:   free_vector(x,1,npar);
                   4129:   free_ivector(indx,1,npar);
1.203     brouard  4130:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4131: 
                   4132: 
                   4133: }
                   4134: 
                   4135: /*************** hessian matrix ****************/
                   4136: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4137: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4138:   int i;
                   4139:   int l=1, lmax=20;
1.203     brouard  4140:   double k1,k2, res, fx;
1.132     brouard  4141:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4142:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4143:   int k=0,kmax=10;
                   4144:   double l1;
                   4145: 
                   4146:   fx=func(x);
                   4147:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4148:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4149:     l1=pow(10,l);
                   4150:     delts=delt;
                   4151:     for(k=1 ; k <kmax; k=k+1){
                   4152:       delt = delta*(l1*k);
                   4153:       p2[theta]=x[theta] +delt;
1.145     brouard  4154:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4155:       p2[theta]=x[theta]-delt;
                   4156:       k2=func(p2)-fx;
                   4157:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4158:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4159:       
1.203     brouard  4160: #ifdef DEBUGHESSII
1.126     brouard  4161:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4162:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4163: #endif
                   4164:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4165:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4166:        k=kmax;
                   4167:       }
                   4168:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4169:        k=kmax; l=lmax*10;
1.126     brouard  4170:       }
                   4171:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4172:        delts=delt;
                   4173:       }
1.203     brouard  4174:     } /* End loop k */
1.126     brouard  4175:   }
                   4176:   delti[theta]=delts;
                   4177:   return res; 
                   4178:   
                   4179: }
                   4180: 
1.203     brouard  4181: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4182: {
                   4183:   int i;
1.164     brouard  4184:   int l=1, lmax=20;
1.126     brouard  4185:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4186:   double p2[MAXPARM+1];
1.203     brouard  4187:   int k, kmax=1;
                   4188:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4189: 
                   4190:   int firstime=0;
1.203     brouard  4191:   
1.126     brouard  4192:   fx=func(x);
1.203     brouard  4193:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4194:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4195:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4196:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4197:     k1=func(p2)-fx;
                   4198:   
1.203     brouard  4199:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4200:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4201:     k2=func(p2)-fx;
                   4202:   
1.203     brouard  4203:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4204:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4205:     k3=func(p2)-fx;
                   4206:   
1.203     brouard  4207:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4208:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4209:     k4=func(p2)-fx;
1.203     brouard  4210:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4211:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4212:       firstime=1;
1.203     brouard  4213:       kmax=kmax+10;
1.208     brouard  4214:     }
                   4215:     if(kmax >=10 || firstime ==1){
1.246     brouard  4216:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4217:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4218:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4219:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4220:     }
                   4221: #ifdef DEBUGHESSIJ
                   4222:     v1=hess[thetai][thetai];
                   4223:     v2=hess[thetaj][thetaj];
                   4224:     cv12=res;
                   4225:     /* Computing eigen value of Hessian matrix */
                   4226:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4227:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4228:     if ((lc2 <0) || (lc1 <0) ){
                   4229:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4230:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4231:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4232:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4233:     }
1.126     brouard  4234: #endif
                   4235:   }
                   4236:   return res;
                   4237: }
                   4238: 
1.203     brouard  4239:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4240: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4241: /* { */
                   4242: /*   int i; */
                   4243: /*   int l=1, lmax=20; */
                   4244: /*   double k1,k2,k3,k4,res,fx; */
                   4245: /*   double p2[MAXPARM+1]; */
                   4246: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4247: /*   int k=0,kmax=10; */
                   4248: /*   double l1; */
                   4249:   
                   4250: /*   fx=func(x); */
                   4251: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4252: /*     l1=pow(10,l); */
                   4253: /*     delts=delt; */
                   4254: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4255: /*       delt = delti*(l1*k); */
                   4256: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4257: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4258: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4259: /*       k1=func(p2)-fx; */
                   4260:       
                   4261: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4262: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4263: /*       k2=func(p2)-fx; */
                   4264:       
                   4265: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4266: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4267: /*       k3=func(p2)-fx; */
                   4268:       
                   4269: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4270: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4271: /*       k4=func(p2)-fx; */
                   4272: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4273: /* #ifdef DEBUGHESSIJ */
                   4274: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4275: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4276: /* #endif */
                   4277: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4278: /*     k=kmax; */
                   4279: /*       } */
                   4280: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4281: /*     k=kmax; l=lmax*10; */
                   4282: /*       } */
                   4283: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4284: /*     delts=delt; */
                   4285: /*       } */
                   4286: /*     } /\* End loop k *\/ */
                   4287: /*   } */
                   4288: /*   delti[theta]=delts; */
                   4289: /*   return res;  */
                   4290: /* } */
                   4291: 
                   4292: 
1.126     brouard  4293: /************** Inverse of matrix **************/
                   4294: void ludcmp(double **a, int n, int *indx, double *d) 
                   4295: { 
                   4296:   int i,imax,j,k; 
                   4297:   double big,dum,sum,temp; 
                   4298:   double *vv; 
                   4299:  
                   4300:   vv=vector(1,n); 
                   4301:   *d=1.0; 
                   4302:   for (i=1;i<=n;i++) { 
                   4303:     big=0.0; 
                   4304:     for (j=1;j<=n;j++) 
                   4305:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4306:     if (big == 0.0){
                   4307:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4308:       for (j=1;j<=n;j++) {
                   4309:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4310:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4311:       }
                   4312:       fflush(ficlog);
                   4313:       fclose(ficlog);
                   4314:       nrerror("Singular matrix in routine ludcmp"); 
                   4315:     }
1.126     brouard  4316:     vv[i]=1.0/big; 
                   4317:   } 
                   4318:   for (j=1;j<=n;j++) { 
                   4319:     for (i=1;i<j;i++) { 
                   4320:       sum=a[i][j]; 
                   4321:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4322:       a[i][j]=sum; 
                   4323:     } 
                   4324:     big=0.0; 
                   4325:     for (i=j;i<=n;i++) { 
                   4326:       sum=a[i][j]; 
                   4327:       for (k=1;k<j;k++) 
                   4328:        sum -= a[i][k]*a[k][j]; 
                   4329:       a[i][j]=sum; 
                   4330:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4331:        big=dum; 
                   4332:        imax=i; 
                   4333:       } 
                   4334:     } 
                   4335:     if (j != imax) { 
                   4336:       for (k=1;k<=n;k++) { 
                   4337:        dum=a[imax][k]; 
                   4338:        a[imax][k]=a[j][k]; 
                   4339:        a[j][k]=dum; 
                   4340:       } 
                   4341:       *d = -(*d); 
                   4342:       vv[imax]=vv[j]; 
                   4343:     } 
                   4344:     indx[j]=imax; 
                   4345:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4346:     if (j != n) { 
                   4347:       dum=1.0/(a[j][j]); 
                   4348:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4349:     } 
                   4350:   } 
                   4351:   free_vector(vv,1,n);  /* Doesn't work */
                   4352: ;
                   4353: } 
                   4354: 
                   4355: void lubksb(double **a, int n, int *indx, double b[]) 
                   4356: { 
                   4357:   int i,ii=0,ip,j; 
                   4358:   double sum; 
                   4359:  
                   4360:   for (i=1;i<=n;i++) { 
                   4361:     ip=indx[i]; 
                   4362:     sum=b[ip]; 
                   4363:     b[ip]=b[i]; 
                   4364:     if (ii) 
                   4365:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4366:     else if (sum) ii=i; 
                   4367:     b[i]=sum; 
                   4368:   } 
                   4369:   for (i=n;i>=1;i--) { 
                   4370:     sum=b[i]; 
                   4371:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4372:     b[i]=sum/a[i][i]; 
                   4373:   } 
                   4374: } 
                   4375: 
                   4376: void pstamp(FILE *fichier)
                   4377: {
1.196     brouard  4378:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4379: }
                   4380: 
1.253     brouard  4381: 
                   4382: 
1.126     brouard  4383: /************ Frequencies ********************/
1.251     brouard  4384: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4385:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4386:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4387: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4388:   
1.265     brouard  4389:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4390:   int iind=0, iage=0;
                   4391:   int mi; /* Effective wave */
                   4392:   int first;
                   4393:   double ***freq; /* Frequencies */
1.268     brouard  4394:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4395:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4396:   double *meanq, *stdq, *idq;
1.226     brouard  4397:   double **meanqt;
                   4398:   double *pp, **prop, *posprop, *pospropt;
                   4399:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4400:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4401:   double agebegin, ageend;
                   4402:     
                   4403:   pp=vector(1,nlstate);
1.251     brouard  4404:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4405:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4406:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4407:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4408:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4409:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4410:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4411:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4412:   strcpy(fileresp,"P_");
                   4413:   strcat(fileresp,fileresu);
                   4414:   /*strcat(fileresphtm,fileresu);*/
                   4415:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4416:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4417:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4418:     exit(0);
                   4419:   }
1.240     brouard  4420:   
1.226     brouard  4421:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4422:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4423:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4424:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4425:     fflush(ficlog);
                   4426:     exit(70); 
                   4427:   }
                   4428:   else{
                   4429:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4430: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4431: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4432:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4433:   }
1.237     brouard  4434:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4435:   
1.226     brouard  4436:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4437:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4438:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4439:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4440:     fflush(ficlog);
                   4441:     exit(70); 
1.240     brouard  4442:   } else{
1.226     brouard  4443:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4444: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4445: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4446:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4447:   }
1.240     brouard  4448:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4449:   
1.253     brouard  4450:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4451:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4452:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4453:   j1=0;
1.126     brouard  4454:   
1.227     brouard  4455:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4456:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4457:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4458:   
                   4459:   
1.226     brouard  4460:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4461:      reference=low_education V1=0,V2=0
                   4462:      med_educ                V1=1 V2=0, 
                   4463:      high_educ               V1=0 V2=1
                   4464:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4465:   */
1.249     brouard  4466:   dateintsum=0;
                   4467:   k2cpt=0;
                   4468: 
1.253     brouard  4469:   if(cptcoveff == 0 )
1.265     brouard  4470:     nl=1;  /* Constant and age model only */
1.253     brouard  4471:   else
                   4472:     nl=2;
1.265     brouard  4473: 
                   4474:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4475:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4476:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4477:    *     freq[s1][s2][iage] =0.
                   4478:    *     Loop on iind
                   4479:    *       ++freq[s1][s2][iage] weighted
                   4480:    *     end iind
                   4481:    *     if covariate and j!0
                   4482:    *       headers Variable on one line
                   4483:    *     endif cov j!=0
                   4484:    *     header of frequency table by age
                   4485:    *     Loop on age
                   4486:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4487:    *       pos+=freq[s1][s2][iage] weighted
                   4488:    *       Loop on s1 initial state
                   4489:    *         fprintf(ficresp
                   4490:    *       end s1
                   4491:    *     end age
                   4492:    *     if j!=0 computes starting values
                   4493:    *     end compute starting values
                   4494:    *   end j1
                   4495:    * end nl 
                   4496:    */
1.253     brouard  4497:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4498:     if(nj==1)
                   4499:       j=0;  /* First pass for the constant */
1.265     brouard  4500:     else{
1.253     brouard  4501:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4502:     }
1.251     brouard  4503:     first=1;
1.265     brouard  4504:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4505:       posproptt=0.;
                   4506:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4507:        scanf("%d", i);*/
                   4508:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4509:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4510:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4511:            freq[i][s2][m]=0;
1.251     brouard  4512:       
                   4513:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4514:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4515:          prop[i][m]=0;
                   4516:        posprop[i]=0;
                   4517:        pospropt[i]=0;
                   4518:       }
1.283     brouard  4519:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4520:         idq[z1]=0.;
                   4521:         meanq[z1]=0.;
                   4522:         stdq[z1]=0.;
1.283     brouard  4523:       }
                   4524:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4525:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4526:       /*         meanqt[m][z1]=0.; */
                   4527:       /*       } */
                   4528:       /* }       */
1.251     brouard  4529:       /* dateintsum=0; */
                   4530:       /* k2cpt=0; */
                   4531:       
1.265     brouard  4532:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4533:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4534:        bool=1;
                   4535:        if(j !=0){
                   4536:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4537:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4538:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4539:                /* if(Tvaraff[z1] ==-20){ */
                   4540:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4541:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4542:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4543:                /* }else  */
                   4544:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4545:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4546:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4547:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4548:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4549:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4550:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4551:                } /* Onlyf fixed */
                   4552:              } /* end z1 */
                   4553:            } /* cptcovn > 0 */
                   4554:          } /* end any */
                   4555:        }/* end j==0 */
1.265     brouard  4556:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4557:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4558:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4559:            m=mw[mi][iind];
                   4560:            if(j!=0){
                   4561:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4562:                for (z1=1; z1<=cptcoveff; z1++) {
                   4563:                  if( Fixed[Tmodelind[z1]]==1){
                   4564:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4565:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4566:                                                                                      value is -1, we don't select. It differs from the 
                   4567:                                                                                      constant and age model which counts them. */
                   4568:                      bool=0; /* not selected */
                   4569:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4570:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4571:                      bool=0;
                   4572:                    }
                   4573:                  }
                   4574:                }
                   4575:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4576:            } /* end j==0 */
                   4577:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4578:            if(bool==1){ /*Selected */
1.251     brouard  4579:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4580:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4581:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4582:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4583:              if(m >=firstpass && m <=lastpass){
                   4584:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4585:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4586:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4587:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4588:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4589:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4590:                if (m<lastpass) {
                   4591:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4592:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4593:                  if(s[m][iind]==-1)
                   4594:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4595:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4596:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4597:                    idq[z1]=idq[z1]+weight[iind];
                   4598:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4599:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4600:                  }
1.251     brouard  4601:                  /* if((int)agev[m][iind] == 55) */
                   4602:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4603:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4604:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4605:                }
1.251     brouard  4606:              } /* end if between passes */  
                   4607:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4608:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4609:                k2cpt++;
                   4610:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4611:              }
1.251     brouard  4612:            }else{
                   4613:              bool=1;
                   4614:            }/* end bool 2 */
                   4615:          } /* end m */
1.284     brouard  4616:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4617:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4618:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4619:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4620:          /* } */
1.251     brouard  4621:        } /* end bool */
                   4622:       } /* end iind = 1 to imx */
                   4623:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4624:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4625:       
                   4626:       
                   4627:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4628:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4629:         pstamp(ficresp);
1.251     brouard  4630:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4631:         pstamp(ficresp);
1.251     brouard  4632:        printf( "\n#********** Variable "); 
                   4633:        fprintf(ficresp, "\n#********** Variable "); 
                   4634:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4635:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4636:        fprintf(ficlog, "\n#********** Variable "); 
                   4637:        for (z1=1; z1<=cptcoveff; z1++){
                   4638:          if(!FixedV[Tvaraff[z1]]){
                   4639:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4640:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4641:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4642:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4643:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4644:          }else{
1.251     brouard  4645:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4646:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4647:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4648:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4649:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4650:          }
                   4651:        }
                   4652:        printf( "**********\n#");
                   4653:        fprintf(ficresp, "**********\n#");
                   4654:        fprintf(ficresphtm, "**********</h3>\n");
                   4655:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4656:        fprintf(ficlog, "**********\n");
                   4657:       }
1.284     brouard  4658:       /*
                   4659:        Printing means of quantitative variables if any
                   4660:       */
                   4661:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4662:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4663:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4664:        if(weightopt==1){
                   4665:          printf(" Weighted mean and standard deviation of");
                   4666:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4667:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4668:        }
1.285     brouard  4669:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4670:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4671:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4672:       }
                   4673:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4674:       /*       for(m=1;m<=lastpass;m++){ */
                   4675:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4676:       /*   } */
                   4677:       /* } */
1.283     brouard  4678: 
1.251     brouard  4679:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4680:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4681:         fprintf(ficresp, " Age");
                   4682:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4683:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4684:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4685:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4686:       }
1.265     brouard  4687:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4688:       fprintf(ficresphtm, "\n");
                   4689:       
                   4690:       /* Header of frequency table by age */
                   4691:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4692:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4693:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4694:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4695:          if(s2!=0 && m!=0)
                   4696:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4697:        }
1.226     brouard  4698:       }
1.251     brouard  4699:       fprintf(ficresphtmfr, "\n");
                   4700:     
                   4701:       /* For each age */
                   4702:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4703:        fprintf(ficresphtm,"<tr>");
                   4704:        if(iage==iagemax+1){
                   4705:          fprintf(ficlog,"1");
                   4706:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4707:        }else if(iage==iagemax+2){
                   4708:          fprintf(ficlog,"0");
                   4709:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4710:        }else if(iage==iagemax+3){
                   4711:          fprintf(ficlog,"Total");
                   4712:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4713:        }else{
1.240     brouard  4714:          if(first==1){
1.251     brouard  4715:            first=0;
                   4716:            printf("See log file for details...\n");
                   4717:          }
                   4718:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4719:          fprintf(ficlog,"Age %d", iage);
                   4720:        }
1.265     brouard  4721:        for(s1=1; s1 <=nlstate ; s1++){
                   4722:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4723:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4724:        }
1.265     brouard  4725:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4726:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4727:            pos += freq[s1][m][iage];
                   4728:          if(pp[s1]>=1.e-10){
1.251     brouard  4729:            if(first==1){
1.265     brouard  4730:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4731:            }
1.265     brouard  4732:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4733:          }else{
                   4734:            if(first==1)
1.265     brouard  4735:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4736:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4737:          }
                   4738:        }
                   4739:       
1.265     brouard  4740:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4741:          /* posprop[s1]=0; */
                   4742:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4743:            pp[s1] += freq[s1][m][iage];
                   4744:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4745:       
                   4746:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4747:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4748:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4749:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4750:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4751:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4752:        }
                   4753:        
                   4754:        /* Writing ficresp */
                   4755:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4756:           if( iage <= iagemax){
                   4757:            fprintf(ficresp," %d",iage);
                   4758:           }
                   4759:         }else if( nj==2){
                   4760:           if( iage <= iagemax){
                   4761:            fprintf(ficresp," %d",iage);
                   4762:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4763:           }
1.240     brouard  4764:        }
1.265     brouard  4765:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4766:          if(pos>=1.e-5){
1.251     brouard  4767:            if(first==1)
1.265     brouard  4768:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4769:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4770:          }else{
                   4771:            if(first==1)
1.265     brouard  4772:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4773:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4774:          }
                   4775:          if( iage <= iagemax){
                   4776:            if(pos>=1.e-5){
1.265     brouard  4777:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4778:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4779:               }else if( nj==2){
                   4780:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4781:               }
                   4782:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4783:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4784:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4785:            } else{
                   4786:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4787:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4788:            }
1.240     brouard  4789:          }
1.265     brouard  4790:          pospropt[s1] +=posprop[s1];
                   4791:        } /* end loop s1 */
1.251     brouard  4792:        /* pospropt=0.; */
1.265     brouard  4793:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4794:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4795:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4796:              if(first==1){
1.265     brouard  4797:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4798:              }
1.265     brouard  4799:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4800:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4801:            }
1.265     brouard  4802:            if(s1!=0 && m!=0)
                   4803:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4804:          }
1.265     brouard  4805:        } /* end loop s1 */
1.251     brouard  4806:        posproptt=0.; 
1.265     brouard  4807:        for(s1=1; s1 <=nlstate; s1++){
                   4808:          posproptt += pospropt[s1];
1.251     brouard  4809:        }
                   4810:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4811:        fprintf(ficresphtm,"</tr>\n");
                   4812:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4813:          if(iage <= iagemax)
                   4814:            fprintf(ficresp,"\n");
1.240     brouard  4815:        }
1.251     brouard  4816:        if(first==1)
                   4817:          printf("Others in log...\n");
                   4818:        fprintf(ficlog,"\n");
                   4819:       } /* end loop age iage */
1.265     brouard  4820:       
1.251     brouard  4821:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4822:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4823:        if(posproptt < 1.e-5){
1.265     brouard  4824:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4825:        }else{
1.265     brouard  4826:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4827:        }
1.226     brouard  4828:       }
1.251     brouard  4829:       fprintf(ficresphtm,"</tr>\n");
                   4830:       fprintf(ficresphtm,"</table>\n");
                   4831:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4832:       if(posproptt < 1.e-5){
1.251     brouard  4833:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4834:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4835:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4836:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4837:        invalidvarcomb[j1]=1;
1.226     brouard  4838:       }else{
1.251     brouard  4839:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4840:        invalidvarcomb[j1]=0;
1.226     brouard  4841:       }
1.251     brouard  4842:       fprintf(ficresphtmfr,"</table>\n");
                   4843:       fprintf(ficlog,"\n");
                   4844:       if(j!=0){
                   4845:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4846:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4847:          for(k=1; k <=(nlstate+ndeath); k++){
                   4848:            if (k != i) {
1.265     brouard  4849:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4850:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4851:                  if(j1==1){ /* All dummy covariates to zero */
                   4852:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4853:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4854:                    printf("%d%d ",i,k);
                   4855:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4856:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4857:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4858:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4859:                  }
1.253     brouard  4860:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4861:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4862:                    x[iage]= (double)iage;
                   4863:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4864:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4865:                  }
1.268     brouard  4866:                  /* Some are not finite, but linreg will ignore these ages */
                   4867:                  no=0;
1.253     brouard  4868:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4869:                  pstart[s1]=b;
                   4870:                  pstart[s1-1]=a;
1.252     brouard  4871:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4872:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4873:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4874:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4875:                  printf("%d%d ",i,k);
                   4876:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4877:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4878:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4879:                  ;
                   4880:                }
                   4881:                /* printf("%12.7f )", param[i][jj][k]); */
                   4882:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4883:                s1++; 
1.251     brouard  4884:              } /* end jj */
                   4885:            } /* end k!= i */
                   4886:          } /* end k */
1.265     brouard  4887:        } /* end i, s1 */
1.251     brouard  4888:       } /* end j !=0 */
                   4889:     } /* end selected combination of covariate j1 */
                   4890:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4891:       printf("#Freqsummary: Starting values for the constants:\n");
                   4892:       fprintf(ficlog,"\n");
1.265     brouard  4893:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4894:        for(k=1; k <=(nlstate+ndeath); k++){
                   4895:          if (k != i) {
                   4896:            printf("%d%d ",i,k);
                   4897:            fprintf(ficlog,"%d%d ",i,k);
                   4898:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4899:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4900:              if(jj==1){ /* Age has to be done */
1.265     brouard  4901:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4902:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4903:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4904:              }
                   4905:              /* printf("%12.7f )", param[i][jj][k]); */
                   4906:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4907:              s1++; 
1.250     brouard  4908:            }
1.251     brouard  4909:            printf("\n");
                   4910:            fprintf(ficlog,"\n");
1.250     brouard  4911:          }
                   4912:        }
1.284     brouard  4913:       } /* end of state i */
1.251     brouard  4914:       printf("#Freqsummary\n");
                   4915:       fprintf(ficlog,"\n");
1.265     brouard  4916:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4917:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4918:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4919:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4920:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4921:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4922:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4923:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4924:          /* } */
                   4925:        }
1.265     brouard  4926:       } /* end loop s1 */
1.251     brouard  4927:       
                   4928:       printf("\n");
                   4929:       fprintf(ficlog,"\n");
                   4930:     } /* end j=0 */
1.249     brouard  4931:   } /* end j */
1.252     brouard  4932: 
1.253     brouard  4933:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4934:     for(i=1, jk=1; i <=nlstate; i++){
                   4935:       for(j=1; j <=nlstate+ndeath; j++){
                   4936:        if(j!=i){
                   4937:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4938:          printf("%1d%1d",i,j);
                   4939:          fprintf(ficparo,"%1d%1d",i,j);
                   4940:          for(k=1; k<=ncovmodel;k++){
                   4941:            /*    printf(" %lf",param[i][j][k]); */
                   4942:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4943:            p[jk]=pstart[jk];
                   4944:            printf(" %f ",pstart[jk]);
                   4945:            fprintf(ficparo," %f ",pstart[jk]);
                   4946:            jk++;
                   4947:          }
                   4948:          printf("\n");
                   4949:          fprintf(ficparo,"\n");
                   4950:        }
                   4951:       }
                   4952:     }
                   4953:   } /* end mle=-2 */
1.226     brouard  4954:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4955:   
1.226     brouard  4956:   fclose(ficresp);
                   4957:   fclose(ficresphtm);
                   4958:   fclose(ficresphtmfr);
1.283     brouard  4959:   free_vector(idq,1,nqfveff);
1.226     brouard  4960:   free_vector(meanq,1,nqfveff);
1.284     brouard  4961:   free_vector(stdq,1,nqfveff);
1.226     brouard  4962:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4963:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4964:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4965:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4966:   free_vector(pospropt,1,nlstate);
                   4967:   free_vector(posprop,1,nlstate);
1.251     brouard  4968:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4969:   free_vector(pp,1,nlstate);
                   4970:   /* End of freqsummary */
                   4971: }
1.126     brouard  4972: 
1.268     brouard  4973: /* Simple linear regression */
                   4974: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4975: 
                   4976:   /* y=a+bx regression */
                   4977:   double   sumx = 0.0;                        /* sum of x                      */
                   4978:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4979:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4980:   double   sumy = 0.0;                        /* sum of y                      */
                   4981:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4982:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4983:   double yhat;
                   4984:   
                   4985:   double denom=0;
                   4986:   int i;
                   4987:   int ne=*no;
                   4988:   
                   4989:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4990:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   4991:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   4992:       continue;
                   4993:     }
                   4994:     ne=ne+1;
                   4995:     sumx  += x[i];       
                   4996:     sumx2 += x[i]*x[i];  
                   4997:     sumxy += x[i] * y[i];
                   4998:     sumy  += y[i];      
                   4999:     sumy2 += y[i]*y[i]; 
                   5000:     denom = (ne * sumx2 - sumx*sumx);
                   5001:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5002:   } 
                   5003:   
                   5004:   denom = (ne * sumx2 - sumx*sumx);
                   5005:   if (denom == 0) {
                   5006:     // vertical, slope m is infinity
                   5007:     *b = INFINITY;
                   5008:     *a = 0;
                   5009:     if (r) *r = 0;
                   5010:     return 1;
                   5011:   }
                   5012:   
                   5013:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5014:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5015:   if (r!=NULL) {
                   5016:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5017:       sqrt((sumx2 - sumx*sumx/ne) *
                   5018:           (sumy2 - sumy*sumy/ne));
                   5019:   }
                   5020:   *no=ne;
                   5021:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5022:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5023:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5024:       continue;
                   5025:     }
                   5026:     ne=ne+1;
                   5027:     yhat = y[i] - *a -*b* x[i];
                   5028:     sume2  += yhat * yhat ;       
                   5029:     
                   5030:     denom = (ne * sumx2 - sumx*sumx);
                   5031:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5032:   } 
                   5033:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5034:   *sa= *sb * sqrt(sumx2/ne);
                   5035:   
                   5036:   return 0; 
                   5037: }
                   5038: 
1.126     brouard  5039: /************ Prevalence ********************/
1.227     brouard  5040: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5041: {  
                   5042:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5043:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5044:      We still use firstpass and lastpass as another selection.
                   5045:   */
1.126     brouard  5046:  
1.227     brouard  5047:   int i, m, jk, j1, bool, z1,j, iv;
                   5048:   int mi; /* Effective wave */
                   5049:   int iage;
                   5050:   double agebegin, ageend;
                   5051: 
                   5052:   double **prop;
                   5053:   double posprop; 
                   5054:   double  y2; /* in fractional years */
                   5055:   int iagemin, iagemax;
                   5056:   int first; /** to stop verbosity which is redirected to log file */
                   5057: 
                   5058:   iagemin= (int) agemin;
                   5059:   iagemax= (int) agemax;
                   5060:   /*pp=vector(1,nlstate);*/
1.251     brouard  5061:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5062:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5063:   j1=0;
1.222     brouard  5064:   
1.227     brouard  5065:   /*j=cptcoveff;*/
                   5066:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5067:   
1.288     brouard  5068:   first=0;
1.227     brouard  5069:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5070:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5071:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5072:        prop[i][iage]=0.0;
                   5073:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5074:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5075:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5076:     
                   5077:     for (i=1; i<=imx; i++) { /* Each individual */
                   5078:       bool=1;
                   5079:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5080:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5081:        m=mw[mi][i];
                   5082:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5083:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5084:        for (z1=1; z1<=cptcoveff; z1++){
                   5085:          if( Fixed[Tmodelind[z1]]==1){
                   5086:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5087:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5088:              bool=0;
                   5089:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5090:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5091:              bool=0;
                   5092:            }
                   5093:        }
                   5094:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5095:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5096:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5097:          if(m >=firstpass && m <=lastpass){
                   5098:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5099:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5100:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5101:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5102:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5103:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5104:                exit(1);
                   5105:              }
                   5106:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5107:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5108:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5109:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5110:              } /* end valid statuses */ 
                   5111:            } /* end selection of dates */
                   5112:          } /* end selection of waves */
                   5113:        } /* end bool */
                   5114:       } /* end wave */
                   5115:     } /* end individual */
                   5116:     for(i=iagemin; i <= iagemax+3; i++){  
                   5117:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5118:        posprop += prop[jk][i]; 
                   5119:       } 
                   5120:       
                   5121:       for(jk=1; jk <=nlstate ; jk++){      
                   5122:        if( i <=  iagemax){ 
                   5123:          if(posprop>=1.e-5){ 
                   5124:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5125:          } else{
1.288     brouard  5126:            if(!first){
                   5127:              first=1;
1.266     brouard  5128:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5129:            }else{
1.288     brouard  5130:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5131:            }
                   5132:          }
                   5133:        } 
                   5134:       }/* end jk */ 
                   5135:     }/* end i */ 
1.222     brouard  5136:      /*} *//* end i1 */
1.227     brouard  5137:   } /* end j1 */
1.222     brouard  5138:   
1.227     brouard  5139:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5140:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5141:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5142: }  /* End of prevalence */
1.126     brouard  5143: 
                   5144: /************* Waves Concatenation ***************/
                   5145: 
                   5146: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5147: {
                   5148:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5149:      Death is a valid wave (if date is known).
                   5150:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5151:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5152:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5153:   */
1.126     brouard  5154: 
1.224     brouard  5155:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5156:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5157:      double sum=0., jmean=0.;*/
1.224     brouard  5158:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5159:   int j, k=0,jk, ju, jl;
                   5160:   double sum=0.;
                   5161:   first=0;
1.214     brouard  5162:   firstwo=0;
1.217     brouard  5163:   firsthree=0;
1.218     brouard  5164:   firstfour=0;
1.164     brouard  5165:   jmin=100000;
1.126     brouard  5166:   jmax=-1;
                   5167:   jmean=0.;
1.224     brouard  5168: 
                   5169: /* Treating live states */
1.214     brouard  5170:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5171:     mi=0;  /* First valid wave */
1.227     brouard  5172:     mli=0; /* Last valid wave */
1.126     brouard  5173:     m=firstpass;
1.214     brouard  5174:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5175:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5176:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5177:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5178:        mw[++mi][i]=m;
                   5179:        mli=m;
1.224     brouard  5180:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5181:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5182:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5183:       }
1.227     brouard  5184:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5185: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5186:        break;
1.224     brouard  5187: #else
1.227     brouard  5188:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5189:          if(firsthree == 0){
1.262     brouard  5190:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5191:            firsthree=1;
                   5192:          }
1.262     brouard  5193:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5194:          mw[++mi][i]=m;
                   5195:          mli=m;
                   5196:        }
                   5197:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5198:          nbwarn++;
                   5199:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5200:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5201:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5202:          }
                   5203:          break;
                   5204:        }
                   5205:        break;
1.224     brouard  5206: #endif
1.227     brouard  5207:       }/* End m >= lastpass */
1.126     brouard  5208:     }/* end while */
1.224     brouard  5209: 
1.227     brouard  5210:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5211:     /* After last pass */
1.224     brouard  5212: /* Treating death states */
1.214     brouard  5213:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5214:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5215:       /* } */
1.126     brouard  5216:       mi++;    /* Death is another wave */
                   5217:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5218:       /* Only death is a correct wave */
1.126     brouard  5219:       mw[mi][i]=m;
1.257     brouard  5220:     } /* else not in a death state */
1.224     brouard  5221: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5222:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5223:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5224:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5225:          nbwarn++;
                   5226:          if(firstfiv==0){
                   5227:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5228:            firstfiv=1;
                   5229:          }else{
                   5230:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5231:          }
                   5232:        }else{ /* Death occured afer last wave potential bias */
                   5233:          nberr++;
                   5234:          if(firstwo==0){
1.257     brouard  5235:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5236:            firstwo=1;
                   5237:          }
1.257     brouard  5238:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5239:        }
1.257     brouard  5240:       }else{ /* if date of interview is unknown */
1.227     brouard  5241:        /* death is known but not confirmed by death status at any wave */
                   5242:        if(firstfour==0){
                   5243:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5244:          firstfour=1;
                   5245:        }
                   5246:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5247:       }
1.224     brouard  5248:     } /* end if date of death is known */
                   5249: #endif
                   5250:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5251:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5252:     if(mi==0){
                   5253:       nbwarn++;
                   5254:       if(first==0){
1.227     brouard  5255:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5256:        first=1;
1.126     brouard  5257:       }
                   5258:       if(first==1){
1.227     brouard  5259:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5260:       }
                   5261:     } /* end mi==0 */
                   5262:   } /* End individuals */
1.214     brouard  5263:   /* wav and mw are no more changed */
1.223     brouard  5264:        
1.214     brouard  5265:   
1.126     brouard  5266:   for(i=1; i<=imx; i++){
                   5267:     for(mi=1; mi<wav[i];mi++){
                   5268:       if (stepm <=0)
1.227     brouard  5269:        dh[mi][i]=1;
1.126     brouard  5270:       else{
1.260     brouard  5271:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5272:          if (agedc[i] < 2*AGESUP) {
                   5273:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5274:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5275:            else if(j<0){
                   5276:              nberr++;
                   5277:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5278:              j=1; /* Temporary Dangerous patch */
                   5279:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5280:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5281:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5282:            }
                   5283:            k=k+1;
                   5284:            if (j >= jmax){
                   5285:              jmax=j;
                   5286:              ijmax=i;
                   5287:            }
                   5288:            if (j <= jmin){
                   5289:              jmin=j;
                   5290:              ijmin=i;
                   5291:            }
                   5292:            sum=sum+j;
                   5293:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5294:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5295:          }
                   5296:        }
                   5297:        else{
                   5298:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5299: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5300:                                        
1.227     brouard  5301:          k=k+1;
                   5302:          if (j >= jmax) {
                   5303:            jmax=j;
                   5304:            ijmax=i;
                   5305:          }
                   5306:          else if (j <= jmin){
                   5307:            jmin=j;
                   5308:            ijmin=i;
                   5309:          }
                   5310:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5311:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5312:          if(j<0){
                   5313:            nberr++;
                   5314:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5315:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5316:          }
                   5317:          sum=sum+j;
                   5318:        }
                   5319:        jk= j/stepm;
                   5320:        jl= j -jk*stepm;
                   5321:        ju= j -(jk+1)*stepm;
                   5322:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5323:          if(jl==0){
                   5324:            dh[mi][i]=jk;
                   5325:            bh[mi][i]=0;
                   5326:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5327:                  * to avoid the price of an extra matrix product in likelihood */
                   5328:            dh[mi][i]=jk+1;
                   5329:            bh[mi][i]=ju;
                   5330:          }
                   5331:        }else{
                   5332:          if(jl <= -ju){
                   5333:            dh[mi][i]=jk;
                   5334:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5335:                                 * is higher than the multiple of stepm and negative otherwise.
                   5336:                                 */
                   5337:          }
                   5338:          else{
                   5339:            dh[mi][i]=jk+1;
                   5340:            bh[mi][i]=ju;
                   5341:          }
                   5342:          if(dh[mi][i]==0){
                   5343:            dh[mi][i]=1; /* At least one step */
                   5344:            bh[mi][i]=ju; /* At least one step */
                   5345:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5346:          }
                   5347:        } /* end if mle */
1.126     brouard  5348:       }
                   5349:     } /* end wave */
                   5350:   }
                   5351:   jmean=sum/k;
                   5352:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5353:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5354: }
1.126     brouard  5355: 
                   5356: /*********** Tricode ****************************/
1.220     brouard  5357:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5358:  {
                   5359:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5360:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5361:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5362:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5363:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5364:     */
1.130     brouard  5365: 
1.242     brouard  5366:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5367:    int modmaxcovj=0; /* Modality max of covariates j */
                   5368:    int cptcode=0; /* Modality max of covariates j */
                   5369:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5370: 
                   5371: 
1.242     brouard  5372:    /* cptcoveff=0;  */
                   5373:    /* *cptcov=0; */
1.126     brouard  5374:  
1.242     brouard  5375:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5376:    for (k=1; k <= maxncov; k++)
                   5377:      for(j=1; j<=2; j++)
                   5378:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5379: 
1.242     brouard  5380:    /* Loop on covariates without age and products and no quantitative variable */
                   5381:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5382:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5383:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5384:        switch(Fixed[k]) {
                   5385:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5386:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5387:           ij=(int)(covar[Tvar[k]][i]);
                   5388:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5389:            * If product of Vn*Vm, still boolean *:
                   5390:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5391:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5392:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5393:              modality of the nth covariate of individual i. */
                   5394:           if (ij > modmaxcovj)
                   5395:             modmaxcovj=ij; 
                   5396:           else if (ij < modmincovj) 
                   5397:             modmincovj=ij; 
1.287     brouard  5398:           if (ij <0 || ij >1 ){
                   5399:             printf("Information, IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5400:             fprintf(ficlog,"Information, currently IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5401:           }
                   5402:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5403:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5404:             exit(1);
                   5405:           }else
                   5406:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5407:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5408:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5409:           /* getting the maximum value of the modality of the covariate
                   5410:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5411:              female ies 1, then modmaxcovj=1.
                   5412:           */
                   5413:         } /* end for loop on individuals i */
                   5414:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5415:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5416:         cptcode=modmaxcovj;
                   5417:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5418:         /*for (i=0; i<=cptcode; i++) {*/
                   5419:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5420:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5421:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5422:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5423:             if( j != -1){
                   5424:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5425:                                  covariate for which somebody answered excluding 
                   5426:                                  undefined. Usually 2: 0 and 1. */
                   5427:             }
                   5428:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5429:                                     covariate for which somebody answered including 
                   5430:                                     undefined. Usually 3: -1, 0 and 1. */
                   5431:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5432:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5433:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5434:                        
1.242     brouard  5435:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5436:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5437:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5438:         /* modmincovj=3; modmaxcovj = 7; */
                   5439:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5440:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5441:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5442:         /* nbcode[Tvar[j]][ij]=k; */
                   5443:         /* nbcode[Tvar[j]][1]=0; */
                   5444:         /* nbcode[Tvar[j]][2]=1; */
                   5445:         /* nbcode[Tvar[j]][3]=2; */
                   5446:         /* To be continued (not working yet). */
                   5447:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5448: 
                   5449:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5450:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5451:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5452:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5453:         /*, could be restored in the future */
                   5454:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5455:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5456:             break;
                   5457:           }
                   5458:           ij++;
1.287     brouard  5459:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5460:           cptcode = ij; /* New max modality for covar j */
                   5461:         } /* end of loop on modality i=-1 to 1 or more */
                   5462:         break;
                   5463:        case 1: /* Testing on varying covariate, could be simple and
                   5464:                * should look at waves or product of fixed *
                   5465:                * varying. No time to test -1, assuming 0 and 1 only */
                   5466:         ij=0;
                   5467:         for(i=0; i<=1;i++){
                   5468:           nbcode[Tvar[k]][++ij]=i;
                   5469:         }
                   5470:         break;
                   5471:        default:
                   5472:         break;
                   5473:        } /* end switch */
                   5474:      } /* end dummy test */
1.287     brouard  5475:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5476:   
                   5477:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5478:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5479:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5480:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5481:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5482:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5483:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5484:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5485:   
                   5486:    ij=0;
                   5487:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5488:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5489:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5490:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5491:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5492:        /* If product not in single variable we don't print results */
                   5493:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5494:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5495:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5496:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5497:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5498:        if(Fixed[k]!=0)
                   5499:         anyvaryingduminmodel=1;
                   5500:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5501:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5502:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5503:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5504:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5505:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5506:      } 
                   5507:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5508:    /* ij--; */
                   5509:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5510:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5511:                * because they can be excluded from the model and real
                   5512:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5513:    for(j=ij+1; j<= cptcovt; j++){
                   5514:      Tvaraff[j]=0;
                   5515:      Tmodelind[j]=0;
                   5516:    }
                   5517:    for(j=ntveff+1; j<= cptcovt; j++){
                   5518:      TmodelInvind[j]=0;
                   5519:    }
                   5520:    /* To be sorted */
                   5521:    ;
                   5522:  }
1.126     brouard  5523: 
1.145     brouard  5524: 
1.126     brouard  5525: /*********** Health Expectancies ****************/
                   5526: 
1.235     brouard  5527:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5528: 
                   5529: {
                   5530:   /* Health expectancies, no variances */
1.164     brouard  5531:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5532:   int nhstepma, nstepma; /* Decreasing with age */
                   5533:   double age, agelim, hf;
                   5534:   double ***p3mat;
                   5535:   double eip;
                   5536: 
1.238     brouard  5537:   /* pstamp(ficreseij); */
1.126     brouard  5538:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5539:   fprintf(ficreseij,"# Age");
                   5540:   for(i=1; i<=nlstate;i++){
                   5541:     for(j=1; j<=nlstate;j++){
                   5542:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5543:     }
                   5544:     fprintf(ficreseij," e%1d. ",i);
                   5545:   }
                   5546:   fprintf(ficreseij,"\n");
                   5547: 
                   5548:   
                   5549:   if(estepm < stepm){
                   5550:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5551:   }
                   5552:   else  hstepm=estepm;   
                   5553:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5554:    * This is mainly to measure the difference between two models: for example
                   5555:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5556:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5557:    * progression in between and thus overestimating or underestimating according
                   5558:    * to the curvature of the survival function. If, for the same date, we 
                   5559:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5560:    * to compare the new estimate of Life expectancy with the same linear 
                   5561:    * hypothesis. A more precise result, taking into account a more precise
                   5562:    * curvature will be obtained if estepm is as small as stepm. */
                   5563: 
                   5564:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5565:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5566:      nhstepm is the number of hstepm from age to agelim 
                   5567:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5568:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5569:      and note for a fixed period like estepm months */
                   5570:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5571:      survival function given by stepm (the optimization length). Unfortunately it
                   5572:      means that if the survival funtion is printed only each two years of age and if
                   5573:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5574:      results. So we changed our mind and took the option of the best precision.
                   5575:   */
                   5576:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5577: 
                   5578:   agelim=AGESUP;
                   5579:   /* If stepm=6 months */
                   5580:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5581:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5582:     
                   5583: /* nhstepm age range expressed in number of stepm */
                   5584:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5585:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5586:   /* if (stepm >= YEARM) hstepm=1;*/
                   5587:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5588:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5589: 
                   5590:   for (age=bage; age<=fage; age ++){ 
                   5591:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5592:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5593:     /* if (stepm >= YEARM) hstepm=1;*/
                   5594:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5595: 
                   5596:     /* If stepm=6 months */
                   5597:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5598:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5599:     
1.235     brouard  5600:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5601:     
                   5602:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5603:     
                   5604:     printf("%d|",(int)age);fflush(stdout);
                   5605:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5606:     
                   5607:     /* Computing expectancies */
                   5608:     for(i=1; i<=nlstate;i++)
                   5609:       for(j=1; j<=nlstate;j++)
                   5610:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5611:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5612:          
                   5613:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5614: 
                   5615:        }
                   5616: 
                   5617:     fprintf(ficreseij,"%3.0f",age );
                   5618:     for(i=1; i<=nlstate;i++){
                   5619:       eip=0;
                   5620:       for(j=1; j<=nlstate;j++){
                   5621:        eip +=eij[i][j][(int)age];
                   5622:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5623:       }
                   5624:       fprintf(ficreseij,"%9.4f", eip );
                   5625:     }
                   5626:     fprintf(ficreseij,"\n");
                   5627:     
                   5628:   }
                   5629:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5630:   printf("\n");
                   5631:   fprintf(ficlog,"\n");
                   5632:   
                   5633: }
                   5634: 
1.235     brouard  5635:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5636: 
                   5637: {
                   5638:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5639:      to initial status i, ei. .
1.126     brouard  5640:   */
                   5641:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5642:   int nhstepma, nstepma; /* Decreasing with age */
                   5643:   double age, agelim, hf;
                   5644:   double ***p3matp, ***p3matm, ***varhe;
                   5645:   double **dnewm,**doldm;
                   5646:   double *xp, *xm;
                   5647:   double **gp, **gm;
                   5648:   double ***gradg, ***trgradg;
                   5649:   int theta;
                   5650: 
                   5651:   double eip, vip;
                   5652: 
                   5653:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5654:   xp=vector(1,npar);
                   5655:   xm=vector(1,npar);
                   5656:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5657:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5658:   
                   5659:   pstamp(ficresstdeij);
                   5660:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5661:   fprintf(ficresstdeij,"# Age");
                   5662:   for(i=1; i<=nlstate;i++){
                   5663:     for(j=1; j<=nlstate;j++)
                   5664:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5665:     fprintf(ficresstdeij," e%1d. ",i);
                   5666:   }
                   5667:   fprintf(ficresstdeij,"\n");
                   5668: 
                   5669:   pstamp(ficrescveij);
                   5670:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5671:   fprintf(ficrescveij,"# Age");
                   5672:   for(i=1; i<=nlstate;i++)
                   5673:     for(j=1; j<=nlstate;j++){
                   5674:       cptj= (j-1)*nlstate+i;
                   5675:       for(i2=1; i2<=nlstate;i2++)
                   5676:        for(j2=1; j2<=nlstate;j2++){
                   5677:          cptj2= (j2-1)*nlstate+i2;
                   5678:          if(cptj2 <= cptj)
                   5679:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5680:        }
                   5681:     }
                   5682:   fprintf(ficrescveij,"\n");
                   5683:   
                   5684:   if(estepm < stepm){
                   5685:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5686:   }
                   5687:   else  hstepm=estepm;   
                   5688:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5689:    * This is mainly to measure the difference between two models: for example
                   5690:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5691:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5692:    * progression in between and thus overestimating or underestimating according
                   5693:    * to the curvature of the survival function. If, for the same date, we 
                   5694:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5695:    * to compare the new estimate of Life expectancy with the same linear 
                   5696:    * hypothesis. A more precise result, taking into account a more precise
                   5697:    * curvature will be obtained if estepm is as small as stepm. */
                   5698: 
                   5699:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5700:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5701:      nhstepm is the number of hstepm from age to agelim 
                   5702:      nstepm is the number of stepm from age to agelin. 
                   5703:      Look at hpijx to understand the reason of that which relies in memory size
                   5704:      and note for a fixed period like estepm months */
                   5705:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5706:      survival function given by stepm (the optimization length). Unfortunately it
                   5707:      means that if the survival funtion is printed only each two years of age and if
                   5708:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5709:      results. So we changed our mind and took the option of the best precision.
                   5710:   */
                   5711:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5712: 
                   5713:   /* If stepm=6 months */
                   5714:   /* nhstepm age range expressed in number of stepm */
                   5715:   agelim=AGESUP;
                   5716:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5717:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5718:   /* if (stepm >= YEARM) hstepm=1;*/
                   5719:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5720:   
                   5721:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5722:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5723:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5724:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5725:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5726:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5727: 
                   5728:   for (age=bage; age<=fage; age ++){ 
                   5729:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5730:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5731:     /* if (stepm >= YEARM) hstepm=1;*/
                   5732:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5733:                
1.126     brouard  5734:     /* If stepm=6 months */
                   5735:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5736:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5737:     
                   5738:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5739:                
1.126     brouard  5740:     /* Computing  Variances of health expectancies */
                   5741:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5742:        decrease memory allocation */
                   5743:     for(theta=1; theta <=npar; theta++){
                   5744:       for(i=1; i<=npar; i++){ 
1.222     brouard  5745:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5746:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5747:       }
1.235     brouard  5748:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5749:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5750:                        
1.126     brouard  5751:       for(j=1; j<= nlstate; j++){
1.222     brouard  5752:        for(i=1; i<=nlstate; i++){
                   5753:          for(h=0; h<=nhstepm-1; h++){
                   5754:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5755:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5756:          }
                   5757:        }
1.126     brouard  5758:       }
1.218     brouard  5759:                        
1.126     brouard  5760:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5761:        for(h=0; h<=nhstepm-1; h++){
                   5762:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5763:        }
1.126     brouard  5764:     }/* End theta */
                   5765:     
                   5766:     
                   5767:     for(h=0; h<=nhstepm-1; h++)
                   5768:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5769:        for(theta=1; theta <=npar; theta++)
                   5770:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5771:     
1.218     brouard  5772:                
1.222     brouard  5773:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5774:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5775:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5776:                
1.222     brouard  5777:     printf("%d|",(int)age);fflush(stdout);
                   5778:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5779:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5780:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5781:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5782:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5783:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5784:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5785:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5786:       }
                   5787:     }
1.218     brouard  5788:                
1.126     brouard  5789:     /* Computing expectancies */
1.235     brouard  5790:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5791:     for(i=1; i<=nlstate;i++)
                   5792:       for(j=1; j<=nlstate;j++)
1.222     brouard  5793:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5794:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5795:                                        
1.222     brouard  5796:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5797:                                        
1.222     brouard  5798:        }
1.269     brouard  5799: 
                   5800:     /* Standard deviation of expectancies ij */                
1.126     brouard  5801:     fprintf(ficresstdeij,"%3.0f",age );
                   5802:     for(i=1; i<=nlstate;i++){
                   5803:       eip=0.;
                   5804:       vip=0.;
                   5805:       for(j=1; j<=nlstate;j++){
1.222     brouard  5806:        eip += eij[i][j][(int)age];
                   5807:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5808:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5809:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5810:       }
                   5811:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5812:     }
                   5813:     fprintf(ficresstdeij,"\n");
1.218     brouard  5814:                
1.269     brouard  5815:     /* Variance of expectancies ij */          
1.126     brouard  5816:     fprintf(ficrescveij,"%3.0f",age );
                   5817:     for(i=1; i<=nlstate;i++)
                   5818:       for(j=1; j<=nlstate;j++){
1.222     brouard  5819:        cptj= (j-1)*nlstate+i;
                   5820:        for(i2=1; i2<=nlstate;i2++)
                   5821:          for(j2=1; j2<=nlstate;j2++){
                   5822:            cptj2= (j2-1)*nlstate+i2;
                   5823:            if(cptj2 <= cptj)
                   5824:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5825:          }
1.126     brouard  5826:       }
                   5827:     fprintf(ficrescveij,"\n");
1.218     brouard  5828:                
1.126     brouard  5829:   }
                   5830:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5831:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5832:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5833:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5834:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5835:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5836:   printf("\n");
                   5837:   fprintf(ficlog,"\n");
1.218     brouard  5838:        
1.126     brouard  5839:   free_vector(xm,1,npar);
                   5840:   free_vector(xp,1,npar);
                   5841:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5842:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5843:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5844: }
1.218     brouard  5845:  
1.126     brouard  5846: /************ Variance ******************/
1.235     brouard  5847:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5848:  {
1.279     brouard  5849:    /** Variance of health expectancies 
                   5850:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5851:     * double **newm;
                   5852:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5853:     */
1.218     brouard  5854:   
                   5855:    /* int movingaverage(); */
                   5856:    double **dnewm,**doldm;
                   5857:    double **dnewmp,**doldmp;
                   5858:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  5859:    int first=0;
1.218     brouard  5860:    int k;
                   5861:    double *xp;
1.279     brouard  5862:    double **gp, **gm;  /**< for var eij */
                   5863:    double ***gradg, ***trgradg; /**< for var eij */
                   5864:    double **gradgp, **trgradgp; /**< for var p point j */
                   5865:    double *gpp, *gmp; /**< for var p point j */
                   5866:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5867:    double ***p3mat;
                   5868:    double age,agelim, hf;
                   5869:    /* double ***mobaverage; */
                   5870:    int theta;
                   5871:    char digit[4];
                   5872:    char digitp[25];
                   5873: 
                   5874:    char fileresprobmorprev[FILENAMELENGTH];
                   5875: 
                   5876:    if(popbased==1){
                   5877:      if(mobilav!=0)
                   5878:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5879:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5880:    }
                   5881:    else 
                   5882:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5883: 
1.218     brouard  5884:    /* if (mobilav!=0) { */
                   5885:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5886:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5887:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5888:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5889:    /*   } */
                   5890:    /* } */
                   5891: 
                   5892:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5893:    sprintf(digit,"%-d",ij);
                   5894:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5895:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5896:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5897:    strcat(fileresprobmorprev,fileresu);
                   5898:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5899:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5900:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5901:    }
                   5902:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5903:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5904:    pstamp(ficresprobmorprev);
                   5905:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5906:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5907:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5908:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5909:    }
                   5910:    for(j=1;j<=cptcoveff;j++) 
                   5911:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5912:    fprintf(ficresprobmorprev,"\n");
                   5913: 
1.218     brouard  5914:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5915:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5916:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5917:      for(i=1; i<=nlstate;i++)
                   5918:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5919:    }  
                   5920:    fprintf(ficresprobmorprev,"\n");
                   5921:   
                   5922:    fprintf(ficgp,"\n# Routine varevsij");
                   5923:    fprintf(ficgp,"\nunset title \n");
                   5924:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5925:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5926:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5927: 
1.218     brouard  5928:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5929:    pstamp(ficresvij);
                   5930:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5931:    if(popbased==1)
                   5932:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5933:    else
                   5934:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5935:    fprintf(ficresvij,"# Age");
                   5936:    for(i=1; i<=nlstate;i++)
                   5937:      for(j=1; j<=nlstate;j++)
                   5938:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5939:    fprintf(ficresvij,"\n");
                   5940: 
                   5941:    xp=vector(1,npar);
                   5942:    dnewm=matrix(1,nlstate,1,npar);
                   5943:    doldm=matrix(1,nlstate,1,nlstate);
                   5944:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5945:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5946: 
                   5947:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5948:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5949:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5950:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5951:   
1.218     brouard  5952:    if(estepm < stepm){
                   5953:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5954:    }
                   5955:    else  hstepm=estepm;   
                   5956:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5957:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5958:       nhstepm is the number of hstepm from age to agelim 
                   5959:       nstepm is the number of stepm from age to agelim. 
                   5960:       Look at function hpijx to understand why because of memory size limitations, 
                   5961:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5962:       survival function given by stepm (the optimization length). Unfortunately it
                   5963:       means that if the survival funtion is printed every two years of age and if
                   5964:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5965:       results. So we changed our mind and took the option of the best precision.
                   5966:    */
                   5967:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5968:    agelim = AGESUP;
                   5969:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5970:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5971:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5972:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5973:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5974:      gp=matrix(0,nhstepm,1,nlstate);
                   5975:      gm=matrix(0,nhstepm,1,nlstate);
                   5976:                
                   5977:                
                   5978:      for(theta=1; theta <=npar; theta++){
                   5979:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5980:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5981:        }
1.279     brouard  5982:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   5983:        * returns into prlim .
1.288     brouard  5984:        */
1.242     brouard  5985:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  5986: 
                   5987:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  5988:        if (popbased==1) {
                   5989:         if(mobilav ==0){
                   5990:           for(i=1; i<=nlstate;i++)
                   5991:             prlim[i][i]=probs[(int)age][i][ij];
                   5992:         }else{ /* mobilav */ 
                   5993:           for(i=1; i<=nlstate;i++)
                   5994:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   5995:         }
                   5996:        }
1.279     brouard  5997:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}_x\f$ at horizon h.
                   5998:        */                      
                   5999:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
                   6000:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}_x\f$, which are the probability
                   6001:        * at horizon h in state j including mortality.
                   6002:        */
1.218     brouard  6003:        for(j=1; j<= nlstate; j++){
                   6004:         for(h=0; h<=nhstepm; h++){
                   6005:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6006:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6007:         }
                   6008:        }
1.279     brouard  6009:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6010:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6011:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6012:        */
                   6013:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6014:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6015:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6016:        }
                   6017:        
                   6018:        /* Again with minus shift */
1.218     brouard  6019:                        
                   6020:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6021:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6022: 
1.242     brouard  6023:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6024:                        
                   6025:        if (popbased==1) {
                   6026:         if(mobilav ==0){
                   6027:           for(i=1; i<=nlstate;i++)
                   6028:             prlim[i][i]=probs[(int)age][i][ij];
                   6029:         }else{ /* mobilav */ 
                   6030:           for(i=1; i<=nlstate;i++)
                   6031:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6032:         }
                   6033:        }
                   6034:                        
1.235     brouard  6035:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6036:                        
                   6037:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6038:         for(h=0; h<=nhstepm; h++){
                   6039:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6040:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6041:         }
                   6042:        }
                   6043:        /* This for computing probability of death (h=1 means
                   6044:          computed over hstepm matrices product = hstepm*stepm months) 
                   6045:          as a weighted average of prlim.
                   6046:        */
                   6047:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6048:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6049:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6050:        }    
1.279     brouard  6051:        /* end shifting computations */
                   6052: 
                   6053:        /**< Computing gradient matrix at horizon h 
                   6054:        */
1.218     brouard  6055:        for(j=1; j<= nlstate; j++) /* vareij */
                   6056:         for(h=0; h<=nhstepm; h++){
                   6057:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6058:         }
1.279     brouard  6059:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6060:        */
                   6061:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6062:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6063:        }
                   6064:                        
                   6065:      } /* End theta */
1.279     brouard  6066:      
                   6067:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6068:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6069:                
                   6070:      for(h=0; h<=nhstepm; h++) /* veij */
                   6071:        for(j=1; j<=nlstate;j++)
                   6072:         for(theta=1; theta <=npar; theta++)
                   6073:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6074:                
                   6075:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6076:        for(theta=1; theta <=npar; theta++)
                   6077:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6078:      /**< as well as its transposed matrix 
                   6079:       */               
1.218     brouard  6080:                
                   6081:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6082:      for(i=1;i<=nlstate;i++)
                   6083:        for(j=1;j<=nlstate;j++)
                   6084:         vareij[i][j][(int)age] =0.;
1.279     brouard  6085: 
                   6086:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6087:       * and k (nhstepm) formula 15 of article
                   6088:       * Lievre-Brouard-Heathcote
                   6089:       */
                   6090:      
1.218     brouard  6091:      for(h=0;h<=nhstepm;h++){
                   6092:        for(k=0;k<=nhstepm;k++){
                   6093:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6094:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6095:         for(i=1;i<=nlstate;i++)
                   6096:           for(j=1;j<=nlstate;j++)
                   6097:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6098:        }
                   6099:      }
                   6100:                
1.279     brouard  6101:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6102:       * p.j overall mortality formula 49 but computed directly because
                   6103:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6104:       * wix is independent of theta.
                   6105:       */
1.218     brouard  6106:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6107:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6108:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6109:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6110:         varppt[j][i]=doldmp[j][i];
                   6111:      /* end ppptj */
                   6112:      /*  x centered again */
                   6113:                
1.242     brouard  6114:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6115:                
                   6116:      if (popbased==1) {
                   6117:        if(mobilav ==0){
                   6118:         for(i=1; i<=nlstate;i++)
                   6119:           prlim[i][i]=probs[(int)age][i][ij];
                   6120:        }else{ /* mobilav */ 
                   6121:         for(i=1; i<=nlstate;i++)
                   6122:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6123:        }
                   6124:      }
                   6125:                
                   6126:      /* This for computing probability of death (h=1 means
                   6127:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6128:        as a weighted average of prlim.
                   6129:      */
1.235     brouard  6130:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6131:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6132:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6133:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6134:      }    
                   6135:      /* end probability of death */
                   6136:                
                   6137:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6138:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6139:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6140:        for(i=1; i<=nlstate;i++){
                   6141:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6142:        }
                   6143:      } 
                   6144:      fprintf(ficresprobmorprev,"\n");
                   6145:                
                   6146:      fprintf(ficresvij,"%.0f ",age );
                   6147:      for(i=1; i<=nlstate;i++)
                   6148:        for(j=1; j<=nlstate;j++){
                   6149:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6150:        }
                   6151:      fprintf(ficresvij,"\n");
                   6152:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6153:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6154:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6155:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6156:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6157:    } /* End age */
                   6158:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6159:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6160:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6161:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6162:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6163:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6164:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6165:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6166:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6167:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6168:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6169:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6170:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6171:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6172:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6173:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6174:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6175:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6176:     */
1.218     brouard  6177:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6178:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6179: 
1.218     brouard  6180:    free_vector(xp,1,npar);
                   6181:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6182:    free_matrix(dnewm,1,nlstate,1,npar);
                   6183:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6184:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6185:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6186:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6187:    fclose(ficresprobmorprev);
                   6188:    fflush(ficgp);
                   6189:    fflush(fichtm); 
                   6190:  }  /* end varevsij */
1.126     brouard  6191: 
                   6192: /************ Variance of prevlim ******************/
1.269     brouard  6193:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6194: {
1.205     brouard  6195:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6196:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6197: 
1.268     brouard  6198:   double **dnewmpar,**doldm;
1.126     brouard  6199:   int i, j, nhstepm, hstepm;
                   6200:   double *xp;
                   6201:   double *gp, *gm;
                   6202:   double **gradg, **trgradg;
1.208     brouard  6203:   double **mgm, **mgp;
1.126     brouard  6204:   double age,agelim;
                   6205:   int theta;
                   6206:   
                   6207:   pstamp(ficresvpl);
1.288     brouard  6208:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6209:   fprintf(ficresvpl,"# Age ");
                   6210:   if(nresult >=1)
                   6211:     fprintf(ficresvpl," Result# ");
1.126     brouard  6212:   for(i=1; i<=nlstate;i++)
                   6213:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6214:   fprintf(ficresvpl,"\n");
                   6215: 
                   6216:   xp=vector(1,npar);
1.268     brouard  6217:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6218:   doldm=matrix(1,nlstate,1,nlstate);
                   6219:   
                   6220:   hstepm=1*YEARM; /* Every year of age */
                   6221:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6222:   agelim = AGESUP;
                   6223:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6224:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6225:     if (stepm >= YEARM) hstepm=1;
                   6226:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6227:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6228:     mgp=matrix(1,npar,1,nlstate);
                   6229:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6230:     gp=vector(1,nlstate);
                   6231:     gm=vector(1,nlstate);
                   6232: 
                   6233:     for(theta=1; theta <=npar; theta++){
                   6234:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6235:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6236:       }
1.288     brouard  6237:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6238:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6239:       /* else */
                   6240:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6241:       for(i=1;i<=nlstate;i++){
1.126     brouard  6242:        gp[i] = prlim[i][i];
1.208     brouard  6243:        mgp[theta][i] = prlim[i][i];
                   6244:       }
1.126     brouard  6245:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6246:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6247:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6248:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6249:       /* else */
                   6250:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6251:       for(i=1;i<=nlstate;i++){
1.126     brouard  6252:        gm[i] = prlim[i][i];
1.208     brouard  6253:        mgm[theta][i] = prlim[i][i];
                   6254:       }
1.126     brouard  6255:       for(i=1;i<=nlstate;i++)
                   6256:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6257:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6258:     } /* End theta */
                   6259: 
                   6260:     trgradg =matrix(1,nlstate,1,npar);
                   6261: 
                   6262:     for(j=1; j<=nlstate;j++)
                   6263:       for(theta=1; theta <=npar; theta++)
                   6264:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6265:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6266:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6267:     /*   for(j=1; j<=nlstate;j++){ */
                   6268:     /*         printf(" %d ",j); */
                   6269:     /*         for(theta=1; theta <=npar; theta++) */
                   6270:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6271:     /*         printf("\n "); */
                   6272:     /*   } */
                   6273:     /* } */
                   6274:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6275:     /*   printf("\n gradg %d ",(int)age); */
                   6276:     /*   for(j=1; j<=nlstate;j++){ */
                   6277:     /*         printf("%d ",j); */
                   6278:     /*         for(theta=1; theta <=npar; theta++) */
                   6279:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6280:     /*         printf("\n "); */
                   6281:     /*   } */
                   6282:     /* } */
1.126     brouard  6283: 
                   6284:     for(i=1;i<=nlstate;i++)
                   6285:       varpl[i][(int)age] =0.;
1.209     brouard  6286:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6287:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6288:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6289:     }else{
1.268     brouard  6290:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6291:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6292:     }
1.126     brouard  6293:     for(i=1;i<=nlstate;i++)
                   6294:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6295: 
                   6296:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6297:     if(nresult >=1)
                   6298:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6299:     for(i=1; i<=nlstate;i++){
1.126     brouard  6300:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6301:       /* for(j=1;j<=nlstate;j++) */
                   6302:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6303:     }
1.126     brouard  6304:     fprintf(ficresvpl,"\n");
                   6305:     free_vector(gp,1,nlstate);
                   6306:     free_vector(gm,1,nlstate);
1.208     brouard  6307:     free_matrix(mgm,1,npar,1,nlstate);
                   6308:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6309:     free_matrix(gradg,1,npar,1,nlstate);
                   6310:     free_matrix(trgradg,1,nlstate,1,npar);
                   6311:   } /* End age */
                   6312: 
                   6313:   free_vector(xp,1,npar);
                   6314:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6315:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6316: 
                   6317: }
                   6318: 
                   6319: 
                   6320: /************ Variance of backprevalence limit ******************/
1.269     brouard  6321:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6322: {
                   6323:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6324:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6325: 
                   6326:   double **dnewmpar,**doldm;
                   6327:   int i, j, nhstepm, hstepm;
                   6328:   double *xp;
                   6329:   double *gp, *gm;
                   6330:   double **gradg, **trgradg;
                   6331:   double **mgm, **mgp;
                   6332:   double age,agelim;
                   6333:   int theta;
                   6334:   
                   6335:   pstamp(ficresvbl);
                   6336:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6337:   fprintf(ficresvbl,"# Age ");
                   6338:   if(nresult >=1)
                   6339:     fprintf(ficresvbl," Result# ");
                   6340:   for(i=1; i<=nlstate;i++)
                   6341:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6342:   fprintf(ficresvbl,"\n");
                   6343: 
                   6344:   xp=vector(1,npar);
                   6345:   dnewmpar=matrix(1,nlstate,1,npar);
                   6346:   doldm=matrix(1,nlstate,1,nlstate);
                   6347:   
                   6348:   hstepm=1*YEARM; /* Every year of age */
                   6349:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6350:   agelim = AGEINF;
                   6351:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6352:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6353:     if (stepm >= YEARM) hstepm=1;
                   6354:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6355:     gradg=matrix(1,npar,1,nlstate);
                   6356:     mgp=matrix(1,npar,1,nlstate);
                   6357:     mgm=matrix(1,npar,1,nlstate);
                   6358:     gp=vector(1,nlstate);
                   6359:     gm=vector(1,nlstate);
                   6360: 
                   6361:     for(theta=1; theta <=npar; theta++){
                   6362:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6363:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6364:       }
                   6365:       if(mobilavproj > 0 )
                   6366:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6367:       else
                   6368:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6369:       for(i=1;i<=nlstate;i++){
                   6370:        gp[i] = bprlim[i][i];
                   6371:        mgp[theta][i] = bprlim[i][i];
                   6372:       }
                   6373:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6374:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6375:        if(mobilavproj > 0 )
                   6376:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6377:        else
                   6378:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6379:       for(i=1;i<=nlstate;i++){
                   6380:        gm[i] = bprlim[i][i];
                   6381:        mgm[theta][i] = bprlim[i][i];
                   6382:       }
                   6383:       for(i=1;i<=nlstate;i++)
                   6384:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6385:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6386:     } /* End theta */
                   6387: 
                   6388:     trgradg =matrix(1,nlstate,1,npar);
                   6389: 
                   6390:     for(j=1; j<=nlstate;j++)
                   6391:       for(theta=1; theta <=npar; theta++)
                   6392:        trgradg[j][theta]=gradg[theta][j];
                   6393:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6394:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6395:     /*   for(j=1; j<=nlstate;j++){ */
                   6396:     /*         printf(" %d ",j); */
                   6397:     /*         for(theta=1; theta <=npar; theta++) */
                   6398:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6399:     /*         printf("\n "); */
                   6400:     /*   } */
                   6401:     /* } */
                   6402:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6403:     /*   printf("\n gradg %d ",(int)age); */
                   6404:     /*   for(j=1; j<=nlstate;j++){ */
                   6405:     /*         printf("%d ",j); */
                   6406:     /*         for(theta=1; theta <=npar; theta++) */
                   6407:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6408:     /*         printf("\n "); */
                   6409:     /*   } */
                   6410:     /* } */
                   6411: 
                   6412:     for(i=1;i<=nlstate;i++)
                   6413:       varbpl[i][(int)age] =0.;
                   6414:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6415:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6416:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6417:     }else{
                   6418:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6419:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6420:     }
                   6421:     for(i=1;i<=nlstate;i++)
                   6422:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6423: 
                   6424:     fprintf(ficresvbl,"%.0f ",age );
                   6425:     if(nresult >=1)
                   6426:       fprintf(ficresvbl,"%d ",nres );
                   6427:     for(i=1; i<=nlstate;i++)
                   6428:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6429:     fprintf(ficresvbl,"\n");
                   6430:     free_vector(gp,1,nlstate);
                   6431:     free_vector(gm,1,nlstate);
                   6432:     free_matrix(mgm,1,npar,1,nlstate);
                   6433:     free_matrix(mgp,1,npar,1,nlstate);
                   6434:     free_matrix(gradg,1,npar,1,nlstate);
                   6435:     free_matrix(trgradg,1,nlstate,1,npar);
                   6436:   } /* End age */
                   6437: 
                   6438:   free_vector(xp,1,npar);
                   6439:   free_matrix(doldm,1,nlstate,1,npar);
                   6440:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6441: 
                   6442: }
                   6443: 
                   6444: /************ Variance of one-step probabilities  ******************/
                   6445: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6446:  {
                   6447:    int i, j=0,  k1, l1, tj;
                   6448:    int k2, l2, j1,  z1;
                   6449:    int k=0, l;
                   6450:    int first=1, first1, first2;
                   6451:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6452:    double **dnewm,**doldm;
                   6453:    double *xp;
                   6454:    double *gp, *gm;
                   6455:    double **gradg, **trgradg;
                   6456:    double **mu;
                   6457:    double age, cov[NCOVMAX+1];
                   6458:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6459:    int theta;
                   6460:    char fileresprob[FILENAMELENGTH];
                   6461:    char fileresprobcov[FILENAMELENGTH];
                   6462:    char fileresprobcor[FILENAMELENGTH];
                   6463:    double ***varpij;
                   6464: 
                   6465:    strcpy(fileresprob,"PROB_"); 
                   6466:    strcat(fileresprob,fileres);
                   6467:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6468:      printf("Problem with resultfile: %s\n", fileresprob);
                   6469:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6470:    }
                   6471:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6472:    strcat(fileresprobcov,fileresu);
                   6473:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6474:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6475:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6476:    }
                   6477:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6478:    strcat(fileresprobcor,fileresu);
                   6479:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6480:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6481:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6482:    }
                   6483:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6484:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6485:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6486:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6487:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6488:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6489:    pstamp(ficresprob);
                   6490:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6491:    fprintf(ficresprob,"# Age");
                   6492:    pstamp(ficresprobcov);
                   6493:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6494:    fprintf(ficresprobcov,"# Age");
                   6495:    pstamp(ficresprobcor);
                   6496:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6497:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6498: 
                   6499: 
1.222     brouard  6500:    for(i=1; i<=nlstate;i++)
                   6501:      for(j=1; j<=(nlstate+ndeath);j++){
                   6502:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6503:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6504:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6505:      }  
                   6506:    /* fprintf(ficresprob,"\n");
                   6507:       fprintf(ficresprobcov,"\n");
                   6508:       fprintf(ficresprobcor,"\n");
                   6509:    */
                   6510:    xp=vector(1,npar);
                   6511:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6512:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6513:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6514:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6515:    first=1;
                   6516:    fprintf(ficgp,"\n# Routine varprob");
                   6517:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6518:    fprintf(fichtm,"\n");
                   6519: 
1.288     brouard  6520:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6521:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6522:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6523: and drawn. It helps understanding how is the covariance between two incidences.\
                   6524:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6525:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6526: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6527: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6528: standard deviations wide on each axis. <br>\
                   6529:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6530:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6531: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6532: 
1.222     brouard  6533:    cov[1]=1;
                   6534:    /* tj=cptcoveff; */
1.225     brouard  6535:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6536:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6537:    j1=0;
1.224     brouard  6538:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6539:      if  (cptcovn>0) {
                   6540:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6541:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6542:        fprintf(ficresprob, "**********\n#\n");
                   6543:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6544:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6545:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6546:                        
1.222     brouard  6547:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6548:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6549:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6550:                        
                   6551:                        
1.222     brouard  6552:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6553:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6554:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6555:                        
1.222     brouard  6556:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6557:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6558:        fprintf(ficresprobcor, "**********\n#");    
                   6559:        if(invalidvarcomb[j1]){
                   6560:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6561:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6562:         continue;
                   6563:        }
                   6564:      }
                   6565:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6566:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6567:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6568:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6569:      for (age=bage; age<=fage; age ++){ 
                   6570:        cov[2]=age;
                   6571:        if(nagesqr==1)
                   6572:         cov[3]= age*age;
                   6573:        for (k=1; k<=cptcovn;k++) {
                   6574:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6575:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6576:                                                                    * 1  1 1 1 1
                   6577:                                                                    * 2  2 1 1 1
                   6578:                                                                    * 3  1 2 1 1
                   6579:                                                                    */
                   6580:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6581:        }
                   6582:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6583:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6584:        for (k=1; k<=cptcovprod;k++)
                   6585:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6586:                        
                   6587:                        
1.222     brouard  6588:        for(theta=1; theta <=npar; theta++){
                   6589:         for(i=1; i<=npar; i++)
                   6590:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6591:                                
1.222     brouard  6592:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6593:                                
1.222     brouard  6594:         k=0;
                   6595:         for(i=1; i<= (nlstate); i++){
                   6596:           for(j=1; j<=(nlstate+ndeath);j++){
                   6597:             k=k+1;
                   6598:             gp[k]=pmmij[i][j];
                   6599:           }
                   6600:         }
1.220     brouard  6601:                                
1.222     brouard  6602:         for(i=1; i<=npar; i++)
                   6603:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6604:                                
1.222     brouard  6605:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6606:         k=0;
                   6607:         for(i=1; i<=(nlstate); i++){
                   6608:           for(j=1; j<=(nlstate+ndeath);j++){
                   6609:             k=k+1;
                   6610:             gm[k]=pmmij[i][j];
                   6611:           }
                   6612:         }
1.220     brouard  6613:                                
1.222     brouard  6614:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6615:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6616:        }
1.126     brouard  6617: 
1.222     brouard  6618:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6619:         for(theta=1; theta <=npar; theta++)
                   6620:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6621:                        
1.222     brouard  6622:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6623:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6624:                        
1.222     brouard  6625:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6626:                        
1.222     brouard  6627:        k=0;
                   6628:        for(i=1; i<=(nlstate); i++){
                   6629:         for(j=1; j<=(nlstate+ndeath);j++){
                   6630:           k=k+1;
                   6631:           mu[k][(int) age]=pmmij[i][j];
                   6632:         }
                   6633:        }
                   6634:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6635:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6636:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6637:                        
1.222     brouard  6638:        /*printf("\n%d ",(int)age);
                   6639:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6640:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6641:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6642:         }*/
1.220     brouard  6643:                        
1.222     brouard  6644:        fprintf(ficresprob,"\n%d ",(int)age);
                   6645:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6646:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6647:                        
1.222     brouard  6648:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6649:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6650:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6651:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6652:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6653:        }
                   6654:        i=0;
                   6655:        for (k=1; k<=(nlstate);k++){
                   6656:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6657:           i++;
                   6658:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6659:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6660:           for (j=1; j<=i;j++){
                   6661:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6662:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6663:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6664:           }
                   6665:         }
                   6666:        }/* end of loop for state */
                   6667:      } /* end of loop for age */
                   6668:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6669:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6670:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6671:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6672:     
                   6673:      /* Confidence intervalle of pij  */
                   6674:      /*
                   6675:        fprintf(ficgp,"\nunset parametric;unset label");
                   6676:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6677:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6678:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6679:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6680:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6681:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6682:      */
                   6683:                
                   6684:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6685:      first1=1;first2=2;
                   6686:      for (k2=1; k2<=(nlstate);k2++){
                   6687:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6688:         if(l2==k2) continue;
                   6689:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6690:         for (k1=1; k1<=(nlstate);k1++){
                   6691:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6692:             if(l1==k1) continue;
                   6693:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6694:             if(i<=j) continue;
                   6695:             for (age=bage; age<=fage; age ++){ 
                   6696:               if ((int)age %5==0){
                   6697:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6698:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6699:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6700:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6701:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6702:                 c12=cv12/sqrt(v1*v2);
                   6703:                 /* Computing eigen value of matrix of covariance */
                   6704:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6705:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6706:                 if ((lc2 <0) || (lc1 <0) ){
                   6707:                   if(first2==1){
                   6708:                     first1=0;
                   6709:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6710:                   }
                   6711:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6712:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6713:                   /* lc2=fabs(lc2); */
                   6714:                 }
1.220     brouard  6715:                                                                
1.222     brouard  6716:                 /* Eigen vectors */
1.280     brouard  6717:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6718:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6719:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6720:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6721:                 }else
                   6722:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6723:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6724:                 v21=(lc1-v1)/cv12*v11;
                   6725:                 v12=-v21;
                   6726:                 v22=v11;
                   6727:                 tnalp=v21/v11;
                   6728:                 if(first1==1){
                   6729:                   first1=0;
                   6730:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6731:                 }
                   6732:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6733:                 /*printf(fignu*/
                   6734:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6735:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6736:                 if(first==1){
                   6737:                   first=0;
                   6738:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6739:                   fprintf(ficgp,"\nset parametric;unset label");
                   6740:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6741:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6742:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6743:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6744: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6745:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6746:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6747:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6748:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6749:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6750:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6751:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6752:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6753:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6754:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6755:                 }else{
                   6756:                   first=0;
                   6757:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6758:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6759:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6760:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6761:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6762:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6763:                 }/* if first */
                   6764:               } /* age mod 5 */
                   6765:             } /* end loop age */
                   6766:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6767:             first=1;
                   6768:           } /*l12 */
                   6769:         } /* k12 */
                   6770:        } /*l1 */
                   6771:      }/* k1 */
                   6772:    }  /* loop on combination of covariates j1 */
                   6773:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6774:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6775:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6776:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6777:    free_vector(xp,1,npar);
                   6778:    fclose(ficresprob);
                   6779:    fclose(ficresprobcov);
                   6780:    fclose(ficresprobcor);
                   6781:    fflush(ficgp);
                   6782:    fflush(fichtmcov);
                   6783:  }
1.126     brouard  6784: 
                   6785: 
                   6786: /******************* Printing html file ***********/
1.201     brouard  6787: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6788:                  int lastpass, int stepm, int weightopt, char model[],\
                   6789:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6790:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6791:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6792:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6793:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6794: 
                   6795:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6796:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6797: </ul>");
1.237     brouard  6798:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6799: </ul>", model);
1.214     brouard  6800:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6801:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6802:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6803:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6804:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6805:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6806:    fprintf(fichtm,"\
                   6807:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6808:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6809:    fprintf(fichtm,"\
1.217     brouard  6810:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6811:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6812:    fprintf(fichtm,"\
1.288     brouard  6813:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6814:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6815:    fprintf(fichtm,"\
1.288     brouard  6816:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6817:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6818:    fprintf(fichtm,"\
1.211     brouard  6819:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6820:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6821:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6822:    if(prevfcast==1){
                   6823:      fprintf(fichtm,"\
                   6824:  - Prevalence projections by age and states:                           \
1.201     brouard  6825:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6826:    }
1.126     brouard  6827: 
                   6828: 
1.225     brouard  6829:    m=pow(2,cptcoveff);
1.222     brouard  6830:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6831: 
1.264     brouard  6832:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6833: 
                   6834:    jj1=0;
                   6835: 
                   6836:    fprintf(fichtm," \n<ul>");
                   6837:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6838:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6839:      if(m != 1 && TKresult[nres]!= k1)
                   6840:        continue;
                   6841:      jj1++;
                   6842:      if (cptcovn > 0) {
                   6843:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6844:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6845:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6846:        }
                   6847:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6848:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6849:        }
                   6850:        fprintf(fichtm,"\">");
                   6851:        
                   6852:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6853:        fprintf(fichtm,"************ Results for covariates");
                   6854:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6855:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6856:        }
                   6857:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6858:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6859:        }
                   6860:        if(invalidvarcomb[k1]){
                   6861:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6862:         continue;
                   6863:        }
                   6864:        fprintf(fichtm,"</a></li>");
                   6865:      } /* cptcovn >0 */
                   6866:    }
                   6867:      fprintf(fichtm," \n</ul>");
                   6868: 
1.222     brouard  6869:    jj1=0;
1.237     brouard  6870: 
                   6871:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6872:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6873:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6874:        continue;
1.220     brouard  6875: 
1.222     brouard  6876:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6877:      jj1++;
                   6878:      if (cptcovn > 0) {
1.264     brouard  6879:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6880:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6881:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6882:        }
                   6883:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6884:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6885:        }
                   6886:        fprintf(fichtm,"\"</a>");
                   6887:  
1.222     brouard  6888:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6889:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6890:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6891:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6892:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6893:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6894:        }
1.237     brouard  6895:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6896:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6897:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6898:       }
                   6899:        
1.230     brouard  6900:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6901:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6902:        if(invalidvarcomb[k1]){
                   6903:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6904:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6905:         continue;
                   6906:        }
                   6907:      }
                   6908:      /* aij, bij */
1.259     brouard  6909:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6910: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6911:      /* Pij */
1.241     brouard  6912:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6913: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6914:      /* Quasi-incidences */
                   6915:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6916:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6917:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6918: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6919: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6920:      /* Survival functions (period) in state j */
                   6921:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6922:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6923: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6924:      }
                   6925:      /* State specific survival functions (period) */
                   6926:      for(cpt=1; cpt<=nlstate;cpt++){
                   6927:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6928:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.283     brouard  6929:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6930:      }
1.288     brouard  6931:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  6932:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6933:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6934: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6935:      }
                   6936:      if(backcast==1){
1.288     brouard  6937:        /* Backward prevalence in each health state */
1.222     brouard  6938:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6939:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6940: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6941:        }
1.217     brouard  6942:      }
1.222     brouard  6943:      if(prevfcast==1){
1.288     brouard  6944:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  6945:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  6946:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.273     brouard  6947: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6948:        }
                   6949:      }
1.268     brouard  6950:      if(backcast==1){
                   6951:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6952:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6953:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6954:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6955:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6956: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6957:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6958:        }
                   6959:      }
1.220     brouard  6960:         
1.222     brouard  6961:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6962:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6963: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6964:      }
                   6965:      /* } /\* end i1 *\/ */
                   6966:    }/* End k1 */
                   6967:    fprintf(fichtm,"</ul>");
1.126     brouard  6968: 
1.222     brouard  6969:    fprintf(fichtm,"\
1.126     brouard  6970: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6971:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6972:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6973: But because parameters are usually highly correlated (a higher incidence of disability \
                   6974: and a higher incidence of recovery can give very close observed transition) it might \
                   6975: be very useful to look not only at linear confidence intervals estimated from the \
                   6976: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6977: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6978: covariance matrix of the one-step probabilities. \
                   6979: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6980: 
1.222     brouard  6981:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6982:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6983:    fprintf(fichtm,"\
1.126     brouard  6984:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6985:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6986: 
1.222     brouard  6987:    fprintf(fichtm,"\
1.126     brouard  6988:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6989:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6990:    fprintf(fichtm,"\
1.126     brouard  6991:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   6992:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6993:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  6994:    fprintf(fichtm,"\
1.126     brouard  6995:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   6996:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  6997:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  6998:    fprintf(fichtm,"\
1.288     brouard  6999:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7000:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7001:    fprintf(fichtm,"\
1.128     brouard  7002:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7003:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7004:    fprintf(fichtm,"\
1.288     brouard  7005:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7006:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7007: 
                   7008: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7009: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7010: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7011: /*     <br>",fileres,fileres,fileres,fileres); */
                   7012: /*  else  */
                   7013: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7014:    fflush(fichtm);
                   7015:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7016: 
1.225     brouard  7017:    m=pow(2,cptcoveff);
1.222     brouard  7018:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7019: 
1.222     brouard  7020:    jj1=0;
1.237     brouard  7021: 
1.241     brouard  7022:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7023:    for(k1=1; k1<=m;k1++){
1.253     brouard  7024:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7025:        continue;
1.222     brouard  7026:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7027:      jj1++;
1.126     brouard  7028:      if (cptcovn > 0) {
                   7029:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7030:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7031:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7032:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7033:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7034:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7035:       }
                   7036: 
1.126     brouard  7037:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7038: 
1.222     brouard  7039:        if(invalidvarcomb[k1]){
                   7040:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7041:         continue;
                   7042:        }
1.126     brouard  7043:      }
                   7044:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7045:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7046: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7047: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7048:      }
                   7049:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7050: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7051: true period expectancies (those weighted with period prevalences are also\
                   7052:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7053:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7054: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7055:      /* } /\* end i1 *\/ */
                   7056:    }/* End k1 */
1.241     brouard  7057:   }/* End nres */
1.222     brouard  7058:    fprintf(fichtm,"</ul>");
                   7059:    fflush(fichtm);
1.126     brouard  7060: }
                   7061: 
                   7062: /******************* Gnuplot file **************/
1.270     brouard  7063: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7064: 
                   7065:   char dirfileres[132],optfileres[132];
1.264     brouard  7066:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7067:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7068:   int lv=0, vlv=0, kl=0;
1.130     brouard  7069:   int ng=0;
1.201     brouard  7070:   int vpopbased;
1.223     brouard  7071:   int ioffset; /* variable offset for columns */
1.270     brouard  7072:   int iyearc=1; /* variable column for year of projection  */
                   7073:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7074:   int nres=0; /* Index of resultline */
1.266     brouard  7075:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7076: 
1.126     brouard  7077: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7078: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7079: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7080: /*   } */
                   7081: 
                   7082:   /*#ifdef windows */
                   7083:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7084:   /*#endif */
1.225     brouard  7085:   m=pow(2,cptcoveff);
1.126     brouard  7086: 
1.274     brouard  7087:   /* diagram of the model */
                   7088:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7089:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7090:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7091:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7092: 
                   7093:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7094:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7095:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7096:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7097:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7098:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7099:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7100: 
1.202     brouard  7101:   /* Contribution to likelihood */
                   7102:   /* Plot the probability implied in the likelihood */
1.223     brouard  7103:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7104:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7105:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7106:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7107: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7108:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7109: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7110:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7111:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7112:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7113:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7114:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7115:   for (i=1; i<= nlstate ; i ++) {
                   7116:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7117:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7118:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7119:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7120:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7121:     }
                   7122:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7123:   }
                   7124:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7125:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7126:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7127:   fprintf(ficgp,"\nset out;unset log\n");
                   7128:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7129: 
1.126     brouard  7130:   strcpy(dirfileres,optionfilefiname);
                   7131:   strcpy(optfileres,"vpl");
1.223     brouard  7132:   /* 1eme*/
1.238     brouard  7133:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7134:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7135:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7136:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7137:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7138:          continue;
                   7139:        /* We are interested in selected combination by the resultline */
1.246     brouard  7140:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7141:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7142:        strcpy(gplotlabel,"(");
1.238     brouard  7143:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7144:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7145:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7146:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7147:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7148:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7149:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7150:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7151:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7152:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7153:        }
                   7154:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7155:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7156:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7157:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7158:        }
                   7159:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7160:        /* printf("\n#\n"); */
1.238     brouard  7161:        fprintf(ficgp,"\n#\n");
                   7162:        if(invalidvarcomb[k1]){
1.260     brouard  7163:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7164:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7165:          continue;
                   7166:        }
1.235     brouard  7167:       
1.241     brouard  7168:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7169:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7170:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7171:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7172:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7173:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7174:       /* k1-1 error should be nres-1*/
1.238     brouard  7175:        for (i=1; i<= nlstate ; i ++) {
                   7176:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7177:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7178:        }
1.288     brouard  7179:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7180:        for (i=1; i<= nlstate ; i ++) {
                   7181:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7182:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7183:        } 
1.260     brouard  7184:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7185:        for (i=1; i<= nlstate ; i ++) {
                   7186:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7187:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7188:        }  
1.265     brouard  7189:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7190:        
                   7191:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7192:         if(cptcoveff ==0){
1.271     brouard  7193:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7194:        }else{
                   7195:          kl=0;
                   7196:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7197:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7198:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7199:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7200:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7201:            vlv= nbcode[Tvaraff[k]][lv];
                   7202:            kl++;
                   7203:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7204:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7205:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7206:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7207:            if(k==cptcoveff){
                   7208:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7209:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7210:            }else{
                   7211:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7212:              kl++;
                   7213:            }
                   7214:          } /* end covariate */
                   7215:        } /* end if no covariate */
                   7216: 
1.238     brouard  7217:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7218:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7219:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7220:          if(cptcoveff ==0){
1.245     brouard  7221:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7222:          }else{
                   7223:            kl=0;
                   7224:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7225:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7226:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7227:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7228:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7229:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7230:              kl++;
1.238     brouard  7231:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7232:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7233:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7234:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7235:              if(k==cptcoveff){
1.245     brouard  7236:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7237:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7238:              }else{
                   7239:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7240:                kl++;
                   7241:              }
                   7242:            } /* end covariate */
                   7243:          } /* end if no covariate */
1.268     brouard  7244:          if(backcast == 1){
                   7245:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7246:            /* k1-1 error should be nres-1*/
                   7247:            for (i=1; i<= nlstate ; i ++) {
                   7248:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7249:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7250:            }
1.271     brouard  7251:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7252:            for (i=1; i<= nlstate ; i ++) {
                   7253:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7254:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7255:            } 
1.276     brouard  7256:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7257:            for (i=1; i<= nlstate ; i ++) {
                   7258:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7259:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7260:            } 
1.274     brouard  7261:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7262:          } /* end if backprojcast */
1.238     brouard  7263:        } /* end if backcast */
1.276     brouard  7264:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7265:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7266:       } /* nres */
1.201     brouard  7267:     } /* k1 */
                   7268:   } /* cpt */
1.235     brouard  7269: 
                   7270:   
1.126     brouard  7271:   /*2 eme*/
1.238     brouard  7272:   for (k1=1; k1<= m ; k1 ++){  
                   7273:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7274:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7275:        continue;
                   7276:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7277:       strcpy(gplotlabel,"(");
1.238     brouard  7278:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7279:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7280:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7281:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7282:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7283:        vlv= nbcode[Tvaraff[k]][lv];
                   7284:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7285:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7286:       }
1.237     brouard  7287:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7288:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7289:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7290:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7291:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7292:       }
1.264     brouard  7293:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7294:       fprintf(ficgp,"\n#\n");
1.223     brouard  7295:       if(invalidvarcomb[k1]){
                   7296:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7297:        continue;
                   7298:       }
1.219     brouard  7299:                        
1.241     brouard  7300:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7301:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7302:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7303:        if(vpopbased==0){
1.238     brouard  7304:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7305:        }else
1.238     brouard  7306:          fprintf(ficgp,"\nreplot ");
                   7307:        for (i=1; i<= nlstate+1 ; i ++) {
                   7308:          k=2*i;
1.261     brouard  7309:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7310:          for (j=1; j<= nlstate+1 ; j ++) {
                   7311:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7312:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7313:          }   
                   7314:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7315:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7316:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7317:          for (j=1; j<= nlstate+1 ; j ++) {
                   7318:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7319:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7320:          }   
                   7321:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7322:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7323:          for (j=1; j<= nlstate+1 ; j ++) {
                   7324:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7325:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7326:          }   
                   7327:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7328:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7329:        } /* state */
                   7330:       } /* vpopbased */
1.264     brouard  7331:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7332:     } /* end nres */
                   7333:   } /* k1 end 2 eme*/
                   7334:        
                   7335:        
                   7336:   /*3eme*/
                   7337:   for (k1=1; k1<= m ; k1 ++){
                   7338:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7339:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7340:        continue;
                   7341: 
                   7342:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7343:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7344:        strcpy(gplotlabel,"(");
1.238     brouard  7345:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7346:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7347:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7348:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7349:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7350:          vlv= nbcode[Tvaraff[k]][lv];
                   7351:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7352:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7353:        }
                   7354:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7355:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7356:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7357:        }       
1.264     brouard  7358:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7359:        fprintf(ficgp,"\n#\n");
                   7360:        if(invalidvarcomb[k1]){
                   7361:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7362:          continue;
                   7363:        }
                   7364:                        
                   7365:        /*       k=2+nlstate*(2*cpt-2); */
                   7366:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7367:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7368:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7369:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7370: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7371:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7372:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7373:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7374:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7375:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7376:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7377:                                
1.238     brouard  7378:        */
                   7379:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7380:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7381:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7382:                                
1.238     brouard  7383:        } 
1.261     brouard  7384:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7385:       }
1.264     brouard  7386:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7387:     } /* end nres */
                   7388:   } /* end kl 3eme */
1.126     brouard  7389:   
1.223     brouard  7390:   /* 4eme */
1.201     brouard  7391:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7392:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7393:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7394:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7395:        continue;
1.238     brouard  7396:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7397:        strcpy(gplotlabel,"(");
1.238     brouard  7398:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7399:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7400:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7401:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7402:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7403:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7404:          vlv= nbcode[Tvaraff[k]][lv];
                   7405:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7406:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7407:        }
                   7408:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7409:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7410:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7411:        }       
1.264     brouard  7412:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7413:        fprintf(ficgp,"\n#\n");
                   7414:        if(invalidvarcomb[k1]){
                   7415:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7416:          continue;
1.223     brouard  7417:        }
1.238     brouard  7418:       
1.241     brouard  7419:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7420:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7421:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7422: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7423:        k=3;
                   7424:        for (i=1; i<= nlstate ; i ++){
                   7425:          if(i==1){
                   7426:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7427:          }else{
                   7428:            fprintf(ficgp,", '' ");
                   7429:          }
                   7430:          l=(nlstate+ndeath)*(i-1)+1;
                   7431:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7432:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7433:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7434:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7435:        } /* nlstate */
1.264     brouard  7436:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7437:       } /* end cpt state*/ 
                   7438:     } /* end nres */
                   7439:   } /* end covariate k1 */  
                   7440: 
1.220     brouard  7441: /* 5eme */
1.201     brouard  7442:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7443:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7444:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7445:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7446:        continue;
1.238     brouard  7447:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7448:        strcpy(gplotlabel,"(");
1.238     brouard  7449:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7450:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7451:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7452:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7453:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7454:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7455:          vlv= nbcode[Tvaraff[k]][lv];
                   7456:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7457:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7458:        }
                   7459:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7460:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7461:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7462:        }       
1.264     brouard  7463:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7464:        fprintf(ficgp,"\n#\n");
                   7465:        if(invalidvarcomb[k1]){
                   7466:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7467:          continue;
                   7468:        }
1.227     brouard  7469:       
1.241     brouard  7470:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7471:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7472:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7473: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7474:        k=3;
                   7475:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7476:          if(j==1)
                   7477:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7478:          else
                   7479:            fprintf(ficgp,", '' ");
                   7480:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7481:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7482:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7483:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7484:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7485:        } /* nlstate */
                   7486:        fprintf(ficgp,", '' ");
                   7487:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7488:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7489:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7490:          if(j < nlstate)
                   7491:            fprintf(ficgp,"$%d +",k+l);
                   7492:          else
                   7493:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7494:        }
1.264     brouard  7495:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7496:       } /* end cpt state*/ 
                   7497:     } /* end covariate */  
                   7498:   } /* end nres */
1.227     brouard  7499:   
1.220     brouard  7500: /* 6eme */
1.202     brouard  7501:   /* CV preval stable (period) for each covariate */
1.237     brouard  7502:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7503:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7504:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7505:       continue;
1.255     brouard  7506:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7507:       strcpy(gplotlabel,"(");      
1.288     brouard  7508:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7509:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7510:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7511:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7512:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7513:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7514:        vlv= nbcode[Tvaraff[k]][lv];
                   7515:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7516:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7517:       }
1.237     brouard  7518:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7519:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7520:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7521:       }        
1.264     brouard  7522:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7523:       fprintf(ficgp,"\n#\n");
1.223     brouard  7524:       if(invalidvarcomb[k1]){
1.227     brouard  7525:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7526:        continue;
1.223     brouard  7527:       }
1.227     brouard  7528:       
1.241     brouard  7529:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7530:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7531:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7532: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7533:       k=3; /* Offset */
1.255     brouard  7534:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7535:        if(i==1)
                   7536:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7537:        else
                   7538:          fprintf(ficgp,", '' ");
1.255     brouard  7539:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7540:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7541:        for (j=2; j<= nlstate ; j ++)
                   7542:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7543:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7544:       } /* nlstate */
1.264     brouard  7545:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7546:     } /* end cpt state*/ 
                   7547:   } /* end covariate */  
1.227     brouard  7548:   
                   7549:   
1.220     brouard  7550: /* 7eme */
1.218     brouard  7551:   if(backcast == 1){
1.288     brouard  7552:     /* CV backward prevalence  for each covariate */
1.237     brouard  7553:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7554:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7555:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7556:        continue;
1.268     brouard  7557:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7558:        strcpy(gplotlabel,"(");      
1.288     brouard  7559:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7560:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7561:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7562:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7563:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7564:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7565:          vlv= nbcode[Tvaraff[k]][lv];
                   7566:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7567:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7568:        }
1.237     brouard  7569:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7570:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7571:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7572:        }       
1.264     brouard  7573:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7574:        fprintf(ficgp,"\n#\n");
                   7575:        if(invalidvarcomb[k1]){
                   7576:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7577:          continue;
                   7578:        }
                   7579:        
1.241     brouard  7580:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7581:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7582:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7583: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7584:        k=3; /* Offset */
1.268     brouard  7585:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7586:          if(i==1)
                   7587:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7588:          else
                   7589:            fprintf(ficgp,", '' ");
                   7590:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7591:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7592:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7593:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7594:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7595:          /* for (j=2; j<= nlstate ; j ++) */
                   7596:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7597:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7598:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7599:        } /* nlstate */
1.264     brouard  7600:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7601:       } /* end cpt state*/ 
                   7602:     } /* end covariate */  
                   7603:   } /* End if backcast */
                   7604:   
1.223     brouard  7605:   /* 8eme */
1.218     brouard  7606:   if(prevfcast==1){
1.288     brouard  7607:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7608:     
1.237     brouard  7609:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7610:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7611:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7612:        continue;
1.211     brouard  7613:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7614:        strcpy(gplotlabel,"(");      
1.288     brouard  7615:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7616:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7617:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7618:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7619:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7620:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7621:          vlv= nbcode[Tvaraff[k]][lv];
                   7622:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7623:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7624:        }
1.237     brouard  7625:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7626:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7627:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7628:        }       
1.264     brouard  7629:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7630:        fprintf(ficgp,"\n#\n");
                   7631:        if(invalidvarcomb[k1]){
                   7632:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7633:          continue;
                   7634:        }
                   7635:        
                   7636:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7637:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7638:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7639:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7640: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7641: 
                   7642:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7643:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7644:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7645:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7646:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7647:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7648:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7649:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7650:          if(i==istart){
1.227     brouard  7651:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7652:          }else{
                   7653:            fprintf(ficgp,",\\\n '' ");
                   7654:          }
                   7655:          if(cptcoveff ==0){ /* No covariate */
                   7656:            ioffset=2; /* Age is in 2 */
                   7657:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7658:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7659:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7660:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7661:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7662:            if(i==nlstate+1){
1.270     brouard  7663:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7664:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7665:              fprintf(ficgp,",\\\n '' ");
                   7666:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7667:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7668:                     offyear,                           \
1.268     brouard  7669:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7670:            }else
1.227     brouard  7671:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7672:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7673:          }else{ /* more than 2 covariates */
1.270     brouard  7674:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7675:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7676:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7677:            iyearc=ioffset-1;
                   7678:            iagec=ioffset;
1.227     brouard  7679:            fprintf(ficgp," u %d:(",ioffset); 
                   7680:            kl=0;
                   7681:            strcpy(gplotcondition,"(");
                   7682:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7683:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7684:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7685:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7686:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7687:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7688:              kl++;
                   7689:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7690:              kl++;
                   7691:              if(k <cptcoveff && cptcoveff>1)
                   7692:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7693:            }
                   7694:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7695:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7696:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7697:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7698:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7699:            if(i==nlstate+1){
1.270     brouard  7700:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7701:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7702:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7703:              fprintf(ficgp," u %d:(",iagec); 
                   7704:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7705:                      iyearc, iagec, offyear,                           \
                   7706:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7707: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7708:            }else{
                   7709:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7710:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7711:            }
                   7712:          } /* end if covariate */
                   7713:        } /* nlstate */
1.264     brouard  7714:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7715:       } /* end cpt state*/
                   7716:     } /* end covariate */
                   7717:   } /* End if prevfcast */
1.227     brouard  7718:   
1.268     brouard  7719:   if(backcast==1){
                   7720:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7721:     
                   7722:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7723:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7724:       if(m != 1 && TKresult[nres]!= k1)
                   7725:        continue;
                   7726:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7727:        strcpy(gplotlabel,"(");      
                   7728:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7729:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7730:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7731:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7732:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7733:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7734:          vlv= nbcode[Tvaraff[k]][lv];
                   7735:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7736:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7737:        }
                   7738:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7739:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7740:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7741:        }       
                   7742:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7743:        fprintf(ficgp,"\n#\n");
                   7744:        if(invalidvarcomb[k1]){
                   7745:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7746:          continue;
                   7747:        }
                   7748:        
                   7749:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7750:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7751:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7752:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7753: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7754: 
                   7755:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7756:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7757:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7758:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7759:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7760:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7761:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7762:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7763:          if(i==istart){
                   7764:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7765:          }else{
                   7766:            fprintf(ficgp,",\\\n '' ");
                   7767:          }
                   7768:          if(cptcoveff ==0){ /* No covariate */
                   7769:            ioffset=2; /* Age is in 2 */
                   7770:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7771:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7772:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7773:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7774:            fprintf(ficgp," u %d:(", ioffset); 
                   7775:            if(i==nlstate+1){
1.270     brouard  7776:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7777:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7778:              fprintf(ficgp,",\\\n '' ");
                   7779:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7780:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7781:                     offbyear,                          \
                   7782:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7783:            }else
                   7784:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7785:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7786:          }else{ /* more than 2 covariates */
1.270     brouard  7787:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7788:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7789:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7790:            iyearc=ioffset-1;
                   7791:            iagec=ioffset;
1.268     brouard  7792:            fprintf(ficgp," u %d:(",ioffset); 
                   7793:            kl=0;
                   7794:            strcpy(gplotcondition,"(");
                   7795:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7796:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7797:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7798:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7799:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7800:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7801:              kl++;
                   7802:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7803:              kl++;
                   7804:              if(k <cptcoveff && cptcoveff>1)
                   7805:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7806:            }
                   7807:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7808:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7809:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7810:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7811:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7812:            if(i==nlstate+1){
1.270     brouard  7813:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7814:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7815:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7816:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7817:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7818:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7819:                      iyearc,iagec,offbyear,                            \
                   7820:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7821: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7822:            }else{
                   7823:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7824:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7825:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7826:            }
                   7827:          } /* end if covariate */
                   7828:        } /* nlstate */
                   7829:        fprintf(ficgp,"\nset out; unset label;\n");
                   7830:       } /* end cpt state*/
                   7831:     } /* end covariate */
                   7832:   } /* End if backcast */
                   7833:   
1.227     brouard  7834:   
1.238     brouard  7835:   /* 9eme writing MLE parameters */
                   7836:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7837:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7838:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7839:     for(k=1; k <=(nlstate+ndeath); k++){
                   7840:       if (k != i) {
1.227     brouard  7841:        fprintf(ficgp,"#   current state %d\n",k);
                   7842:        for(j=1; j <=ncovmodel; j++){
                   7843:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7844:          jk++; 
                   7845:        }
                   7846:        fprintf(ficgp,"\n");
1.126     brouard  7847:       }
                   7848:     }
1.223     brouard  7849:   }
1.187     brouard  7850:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7851:   
1.145     brouard  7852:   /*goto avoid;*/
1.238     brouard  7853:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7854:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7855:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7856:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7857:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7858:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7859:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7860:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7861:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7862:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7863:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7864:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7865:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7866:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7867:   fprintf(ficgp,"#\n");
1.223     brouard  7868:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7869:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7870:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7871:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7872:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7873:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7874:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7875:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7876:        continue;
1.264     brouard  7877:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7878:       strcpy(gplotlabel,"(");
1.276     brouard  7879:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7880:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7881:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7882:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7883:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7884:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7885:        vlv= nbcode[Tvaraff[k]][lv];
                   7886:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7887:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7888:       }
1.237     brouard  7889:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7890:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7891:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7892:       }        
1.264     brouard  7893:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7894:       fprintf(ficgp,"\n#\n");
1.264     brouard  7895:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7896:       fprintf(ficgp,"\nset key outside ");
                   7897:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7898:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7899:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7900:       if (ng==1){
                   7901:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7902:        fprintf(ficgp,"\nunset log y");
                   7903:       }else if (ng==2){
                   7904:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7905:        fprintf(ficgp,"\nset log y");
                   7906:       }else if (ng==3){
                   7907:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7908:        fprintf(ficgp,"\nset log y");
                   7909:       }else
                   7910:        fprintf(ficgp,"\nunset title ");
                   7911:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7912:       i=1;
                   7913:       for(k2=1; k2<=nlstate; k2++) {
                   7914:        k3=i;
                   7915:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7916:          if (k != k2){
                   7917:            switch( ng) {
                   7918:            case 1:
                   7919:              if(nagesqr==0)
                   7920:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7921:              else /* nagesqr =1 */
                   7922:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7923:              break;
                   7924:            case 2: /* ng=2 */
                   7925:              if(nagesqr==0)
                   7926:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7927:              else /* nagesqr =1 */
                   7928:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7929:              break;
                   7930:            case 3:
                   7931:              if(nagesqr==0)
                   7932:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7933:              else /* nagesqr =1 */
                   7934:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7935:              break;
                   7936:            }
                   7937:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7938:            ijp=1; /* product no age */
                   7939:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7940:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7941:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7942:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7943:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7944:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7945:                    if(DummyV[j]==0){
                   7946:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7947:                    }else{ /* quantitative */
                   7948:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7949:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7950:                    }
                   7951:                    ij++;
1.237     brouard  7952:                  }
1.268     brouard  7953:                } 
                   7954:              }else if(cptcovprod >0){
                   7955:                if(j==Tprod[ijp]) { /* */ 
                   7956:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7957:                  if(ijp <=cptcovprod) { /* Product */
                   7958:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7959:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7960:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7961:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7962:                      }else{ /* Vn is dummy and Vm is quanti */
                   7963:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7964:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7965:                      }
                   7966:                    }else{ /* Vn*Vm Vn is quanti */
                   7967:                      if(DummyV[Tvard[ijp][2]]==0){
                   7968:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7969:                      }else{ /* Both quanti */
                   7970:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7971:                      }
1.237     brouard  7972:                    }
1.268     brouard  7973:                    ijp++;
1.237     brouard  7974:                  }
1.268     brouard  7975:                } /* end Tprod */
1.237     brouard  7976:              } else{  /* simple covariate */
1.264     brouard  7977:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7978:                if(Dummy[j]==0){
                   7979:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7980:                }else{ /* quantitative */
                   7981:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7982:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7983:                }
1.237     brouard  7984:              } /* end simple */
                   7985:            } /* end j */
1.223     brouard  7986:          }else{
                   7987:            i=i-ncovmodel;
                   7988:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7989:              fprintf(ficgp," (1.");
                   7990:          }
1.227     brouard  7991:          
1.223     brouard  7992:          if(ng != 1){
                   7993:            fprintf(ficgp,")/(1");
1.227     brouard  7994:            
1.264     brouard  7995:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  7996:              if(nagesqr==0)
1.264     brouard  7997:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  7998:              else /* nagesqr =1 */
1.264     brouard  7999:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8000:               
1.223     brouard  8001:              ij=1;
                   8002:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8003:                 if(cptcovage >0){ 
                   8004:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8005:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8006:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8007:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8008:                       ij++;
                   8009:                     }
                   8010:                   }
                   8011:                 }else
                   8012:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8013:              }
                   8014:              fprintf(ficgp,")");
                   8015:            }
                   8016:            fprintf(ficgp,")");
                   8017:            if(ng ==2)
1.276     brouard  8018:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8019:            else /* ng= 3 */
1.276     brouard  8020:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8021:          }else{ /* end ng <> 1 */
                   8022:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8023:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8024:          }
                   8025:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8026:            fprintf(ficgp,",");
                   8027:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8028:            fprintf(ficgp,",");
                   8029:          i=i+ncovmodel;
                   8030:        } /* end k */
                   8031:       } /* end k2 */
1.276     brouard  8032:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8033:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8034:     } /* end k1 */
1.223     brouard  8035:   } /* end ng */
                   8036:   /* avoid: */
                   8037:   fflush(ficgp); 
1.126     brouard  8038: }  /* end gnuplot */
                   8039: 
                   8040: 
                   8041: /*************** Moving average **************/
1.219     brouard  8042: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8043:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8044:    
1.222     brouard  8045:    int i, cpt, cptcod;
                   8046:    int modcovmax =1;
                   8047:    int mobilavrange, mob;
                   8048:    int iage=0;
1.288     brouard  8049:    int firstA1=0, firstA2=0;
1.222     brouard  8050: 
1.266     brouard  8051:    double sum=0., sumr=0.;
1.222     brouard  8052:    double age;
1.266     brouard  8053:    double *sumnewp, *sumnewm, *sumnewmr;
                   8054:    double *agemingood, *agemaxgood; 
                   8055:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8056:   
                   8057:   
1.278     brouard  8058:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8059:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8060: 
                   8061:    sumnewp = vector(1,ncovcombmax);
                   8062:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8063:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8064:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8065:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8066:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8067:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8068: 
                   8069:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8070:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8071:      sumnewp[cptcod]=0.;
1.266     brouard  8072:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8073:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8074:    }
                   8075:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8076:   
1.266     brouard  8077:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8078:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8079:      else mobilavrange=mobilav;
                   8080:      for (age=bage; age<=fage; age++)
                   8081:        for (i=1; i<=nlstate;i++)
                   8082:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8083:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8084:      /* We keep the original values on the extreme ages bage, fage and for 
                   8085:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8086:        we use a 5 terms etc. until the borders are no more concerned. 
                   8087:      */ 
                   8088:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8089:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8090:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8091:           sumnewm[cptcod]=0.;
                   8092:           for (i=1; i<=nlstate;i++){
1.222     brouard  8093:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8094:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8095:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8096:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8097:             }
                   8098:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8099:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8100:           } /* end i */
                   8101:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8102:         } /* end cptcod */
1.222     brouard  8103:        }/* end age */
                   8104:      }/* end mob */
1.266     brouard  8105:    }else{
                   8106:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8107:      return -1;
1.266     brouard  8108:    }
                   8109: 
                   8110:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8111:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8112:      if(invalidvarcomb[cptcod]){
                   8113:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8114:        continue;
                   8115:      }
1.219     brouard  8116: 
1.266     brouard  8117:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8118:        sumnewm[cptcod]=0.;
                   8119:        sumnewmr[cptcod]=0.;
                   8120:        for (i=1; i<=nlstate;i++){
                   8121:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8122:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8123:        }
                   8124:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8125:         agemingoodr[cptcod]=age;
                   8126:        }
                   8127:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8128:           agemingood[cptcod]=age;
                   8129:        }
                   8130:      } /* age */
                   8131:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8132:        sumnewm[cptcod]=0.;
1.266     brouard  8133:        sumnewmr[cptcod]=0.;
1.222     brouard  8134:        for (i=1; i<=nlstate;i++){
                   8135:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8136:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8137:        }
                   8138:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8139:         agemaxgoodr[cptcod]=age;
1.222     brouard  8140:        }
                   8141:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8142:         agemaxgood[cptcod]=age;
                   8143:        }
                   8144:      } /* age */
                   8145:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8146:      /* but they will change */
1.288     brouard  8147:      firstA1=0;firstA2=0;
1.266     brouard  8148:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8149:        sumnewm[cptcod]=0.;
                   8150:        sumnewmr[cptcod]=0.;
                   8151:        for (i=1; i<=nlstate;i++){
                   8152:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8153:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8154:        }
                   8155:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8156:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8157:           agemaxgoodr[cptcod]=age;  /* age min */
                   8158:           for (i=1; i<=nlstate;i++)
                   8159:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8160:         }else{ /* bad we change the value with the values of good ages */
                   8161:           for (i=1; i<=nlstate;i++){
                   8162:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8163:           } /* i */
                   8164:         } /* end bad */
                   8165:        }else{
                   8166:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8167:           agemaxgood[cptcod]=age;
                   8168:         }else{ /* bad we change the value with the values of good ages */
                   8169:           for (i=1; i<=nlstate;i++){
                   8170:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8171:           } /* i */
                   8172:         } /* end bad */
                   8173:        }/* end else */
                   8174:        sum=0.;sumr=0.;
                   8175:        for (i=1; i<=nlstate;i++){
                   8176:         sum+=mobaverage[(int)age][i][cptcod];
                   8177:         sumr+=probs[(int)age][i][cptcod];
                   8178:        }
                   8179:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8180:         if(!firstA1){
                   8181:           firstA1=1;
                   8182:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8183:         }
                   8184:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8185:        } /* end bad */
                   8186:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8187:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8188:         if(!firstA2){
                   8189:           firstA2=1;
                   8190:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8191:         }
                   8192:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8193:        } /* end bad */
                   8194:      }/* age */
1.266     brouard  8195: 
                   8196:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8197:        sumnewm[cptcod]=0.;
1.266     brouard  8198:        sumnewmr[cptcod]=0.;
1.222     brouard  8199:        for (i=1; i<=nlstate;i++){
                   8200:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8201:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8202:        } 
                   8203:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8204:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8205:           agemingoodr[cptcod]=age;
                   8206:           for (i=1; i<=nlstate;i++)
                   8207:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8208:         }else{ /* bad we change the value with the values of good ages */
                   8209:           for (i=1; i<=nlstate;i++){
                   8210:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8211:           } /* i */
                   8212:         } /* end bad */
                   8213:        }else{
                   8214:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8215:           agemingood[cptcod]=age;
                   8216:         }else{ /* bad */
                   8217:           for (i=1; i<=nlstate;i++){
                   8218:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8219:           } /* i */
                   8220:         } /* end bad */
                   8221:        }/* end else */
                   8222:        sum=0.;sumr=0.;
                   8223:        for (i=1; i<=nlstate;i++){
                   8224:         sum+=mobaverage[(int)age][i][cptcod];
                   8225:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8226:        }
1.266     brouard  8227:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8228:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8229:        } /* end bad */
                   8230:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8231:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8232:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8233:        } /* end bad */
                   8234:      }/* age */
1.266     brouard  8235: 
1.222     brouard  8236:                
                   8237:      for (age=bage; age<=fage; age++){
1.235     brouard  8238:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8239:        sumnewp[cptcod]=0.;
                   8240:        sumnewm[cptcod]=0.;
                   8241:        for (i=1; i<=nlstate;i++){
                   8242:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8243:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8244:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8245:        }
                   8246:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8247:      }
                   8248:      /* printf("\n"); */
                   8249:      /* } */
1.266     brouard  8250: 
1.222     brouard  8251:      /* brutal averaging */
1.266     brouard  8252:      /* for (i=1; i<=nlstate;i++){ */
                   8253:      /*   for (age=1; age<=bage; age++){ */
                   8254:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8255:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8256:      /*   }     */
                   8257:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8258:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8259:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8260:      /*   } */
                   8261:      /* } /\* end i status *\/ */
                   8262:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8263:      /*   for (age=1; age<=AGESUP; age++){ */
                   8264:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8265:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8266:      /*   } */
                   8267:      /* } */
1.222     brouard  8268:    }/* end cptcod */
1.266     brouard  8269:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8270:    free_vector(agemaxgood,1, ncovcombmax);
                   8271:    free_vector(agemingood,1, ncovcombmax);
                   8272:    free_vector(agemingoodr,1, ncovcombmax);
                   8273:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8274:    free_vector(sumnewm,1, ncovcombmax);
                   8275:    free_vector(sumnewp,1, ncovcombmax);
                   8276:    return 0;
                   8277:  }/* End movingaverage */
1.218     brouard  8278:  
1.126     brouard  8279: 
                   8280: /************** Forecasting ******************/
1.269     brouard  8281:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8282:   /* proj1, year, month, day of starting projection 
                   8283:      agemin, agemax range of age
                   8284:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8285:      anproj2 year of en of projection (same day and month as proj1).
                   8286:   */
1.267     brouard  8287:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8288:   double agec; /* generic age */
                   8289:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8290:   double *popeffectif,*popcount;
                   8291:   double ***p3mat;
1.218     brouard  8292:   /* double ***mobaverage; */
1.126     brouard  8293:   char fileresf[FILENAMELENGTH];
                   8294: 
                   8295:   agelim=AGESUP;
1.211     brouard  8296:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8297:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8298:      We still use firstpass and lastpass as another selection.
                   8299:   */
1.214     brouard  8300:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8301:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8302:  
1.201     brouard  8303:   strcpy(fileresf,"F_"); 
                   8304:   strcat(fileresf,fileresu);
1.126     brouard  8305:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8306:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8307:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8308:   }
1.235     brouard  8309:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8310:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8311: 
1.225     brouard  8312:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8313: 
                   8314: 
                   8315:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8316:   if (stepm<=12) stepsize=1;
                   8317:   if(estepm < stepm){
                   8318:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8319:   }
1.270     brouard  8320:   else{
                   8321:     hstepm=estepm;   
                   8322:   }
                   8323:   if(estepm > stepm){ /* Yes every two year */
                   8324:     stepsize=2;
                   8325:   }
1.126     brouard  8326: 
                   8327:   hstepm=hstepm/stepm; 
                   8328:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8329:                                fractional in yp1 */
                   8330:   anprojmean=yp;
                   8331:   yp2=modf((yp1*12),&yp);
                   8332:   mprojmean=yp;
                   8333:   yp1=modf((yp2*30.5),&yp);
                   8334:   jprojmean=yp;
                   8335:   if(jprojmean==0) jprojmean=1;
                   8336:   if(mprojmean==0) jprojmean=1;
                   8337: 
1.227     brouard  8338:   i1=pow(2,cptcoveff);
1.126     brouard  8339:   if (cptcovn < 1){i1=1;}
                   8340:   
                   8341:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8342:   
                   8343:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8344:   
1.126     brouard  8345: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8346:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8347:   for(k=1; k<=i1;k++){
1.253     brouard  8348:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8349:       continue;
1.227     brouard  8350:     if(invalidvarcomb[k]){
                   8351:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8352:       continue;
                   8353:     }
                   8354:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8355:     for(j=1;j<=cptcoveff;j++) {
                   8356:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8357:     }
1.235     brouard  8358:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8359:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8360:     }
1.227     brouard  8361:     fprintf(ficresf," yearproj age");
                   8362:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8363:       for(i=1; i<=nlstate;i++)               
                   8364:        fprintf(ficresf," p%d%d",i,j);
                   8365:       fprintf(ficresf," wp.%d",j);
                   8366:     }
                   8367:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8368:       fprintf(ficresf,"\n");
                   8369:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8370:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8371:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8372:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8373:        nhstepm = nhstepm/hstepm; 
                   8374:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8375:        oldm=oldms;savm=savms;
1.268     brouard  8376:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8377:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8378:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8379:        for (h=0; h<=nhstepm; h++){
                   8380:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8381:            break;
                   8382:          }
                   8383:        }
                   8384:        fprintf(ficresf,"\n");
                   8385:        for(j=1;j<=cptcoveff;j++) 
                   8386:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8387:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8388:        
                   8389:        for(j=1; j<=nlstate+ndeath;j++) {
                   8390:          ppij=0.;
                   8391:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8392:            if (mobilav>=1)
                   8393:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8394:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8395:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8396:            }
1.268     brouard  8397:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8398:          } /* end i */
                   8399:          fprintf(ficresf," %.3f", ppij);
                   8400:        }/* end j */
1.227     brouard  8401:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8402:       } /* end agec */
1.266     brouard  8403:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8404:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8405:     } /* end yearp */
                   8406:   } /* end  k */
1.219     brouard  8407:        
1.126     brouard  8408:   fclose(ficresf);
1.215     brouard  8409:   printf("End of Computing forecasting \n");
                   8410:   fprintf(ficlog,"End of Computing forecasting\n");
                   8411: 
1.126     brouard  8412: }
                   8413: 
1.269     brouard  8414: /************** Back Forecasting ******************/
                   8415:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8416:   /* back1, year, month, day of starting backection
                   8417:      agemin, agemax range of age
                   8418:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8419:      anback2 year of end of backprojection (same day and month as back1).
                   8420:      prevacurrent and prev are prevalences.
1.267     brouard  8421:   */
                   8422:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8423:   double agec; /* generic age */
1.268     brouard  8424:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8425:   double *popeffectif,*popcount;
                   8426:   double ***p3mat;
                   8427:   /* double ***mobaverage; */
                   8428:   char fileresfb[FILENAMELENGTH];
                   8429:  
1.268     brouard  8430:   agelim=AGEINF;
1.267     brouard  8431:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8432:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8433:      We still use firstpass and lastpass as another selection.
                   8434:   */
                   8435:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8436:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8437: 
                   8438:   /*Do we need to compute prevalence again?*/
                   8439: 
                   8440:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8441:   
                   8442:   strcpy(fileresfb,"FB_");
                   8443:   strcat(fileresfb,fileresu);
                   8444:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8445:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8446:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8447:   }
                   8448:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8449:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8450:   
                   8451:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8452:   
                   8453:    
                   8454:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8455:   if (stepm<=12) stepsize=1;
                   8456:   if(estepm < stepm){
                   8457:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8458:   }
1.270     brouard  8459:   else{
                   8460:     hstepm=estepm;   
                   8461:   }
                   8462:   if(estepm >= stepm){ /* Yes every two year */
                   8463:     stepsize=2;
                   8464:   }
1.267     brouard  8465:   
                   8466:   hstepm=hstepm/stepm;
                   8467:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8468:                                fractional in yp1 */
                   8469:   anprojmean=yp;
                   8470:   yp2=modf((yp1*12),&yp);
                   8471:   mprojmean=yp;
                   8472:   yp1=modf((yp2*30.5),&yp);
                   8473:   jprojmean=yp;
                   8474:   if(jprojmean==0) jprojmean=1;
                   8475:   if(mprojmean==0) jprojmean=1;
                   8476:   
                   8477:   i1=pow(2,cptcoveff);
                   8478:   if (cptcovn < 1){i1=1;}
                   8479:   
                   8480:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8481:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8482:   
                   8483:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8484:   
                   8485:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8486:   for(k=1; k<=i1;k++){
                   8487:     if(i1 != 1 && TKresult[nres]!= k)
                   8488:       continue;
                   8489:     if(invalidvarcomb[k]){
                   8490:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8491:       continue;
                   8492:     }
1.268     brouard  8493:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8494:     for(j=1;j<=cptcoveff;j++) {
                   8495:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8496:     }
                   8497:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8498:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8499:     }
                   8500:     fprintf(ficresfb," yearbproj age");
                   8501:     for(j=1; j<=nlstate+ndeath;j++){
                   8502:       for(i=1; i<=nlstate;i++)
1.268     brouard  8503:        fprintf(ficresfb," b%d%d",i,j);
                   8504:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8505:     }
                   8506:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8507:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8508:       fprintf(ficresfb,"\n");
                   8509:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8510:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8511:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8512:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8513:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8514:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8515:        nhstepm = nhstepm/hstepm;
                   8516:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8517:        oldm=oldms;savm=savms;
1.268     brouard  8518:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8519:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8520:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8521:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8522:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8523:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8524:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8525:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8526:            break;
                   8527:          }
                   8528:        }
                   8529:        fprintf(ficresfb,"\n");
                   8530:        for(j=1;j<=cptcoveff;j++)
                   8531:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8532:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8533:        for(i=1; i<=nlstate+ndeath;i++) {
                   8534:          ppij=0.;ppi=0.;
                   8535:          for(j=1; j<=nlstate;j++) {
                   8536:            /* if (mobilav==1) */
1.269     brouard  8537:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8538:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8539:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8540:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8541:              /* else { */
                   8542:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8543:              /* } */
1.268     brouard  8544:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8545:          } /* end j */
                   8546:          if(ppi <0.99){
                   8547:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8548:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8549:          }
                   8550:          fprintf(ficresfb," %.3f", ppij);
                   8551:        }/* end j */
1.267     brouard  8552:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8553:       } /* end agec */
                   8554:     } /* end yearp */
                   8555:   } /* end k */
1.217     brouard  8556:   
1.267     brouard  8557:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8558:   
1.267     brouard  8559:   fclose(ficresfb);
                   8560:   printf("End of Computing Back forecasting \n");
                   8561:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8562:        
1.267     brouard  8563: }
1.217     brouard  8564: 
1.269     brouard  8565: /* Variance of prevalence limit: varprlim */
                   8566:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8567:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8568:  
                   8569:    char fileresvpl[FILENAMELENGTH];  
                   8570:    FILE *ficresvpl;
                   8571:    double **oldm, **savm;
                   8572:    double **varpl; /* Variances of prevalence limits by age */   
                   8573:    int i1, k, nres, j ;
                   8574:    
                   8575:     strcpy(fileresvpl,"VPL_");
                   8576:     strcat(fileresvpl,fileresu);
                   8577:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8578:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8579:       exit(0);
                   8580:     }
1.288     brouard  8581:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8582:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8583:     
                   8584:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8585:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8586:     
                   8587:     i1=pow(2,cptcoveff);
                   8588:     if (cptcovn < 1){i1=1;}
                   8589: 
                   8590:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8591:     for(k=1; k<=i1;k++){
                   8592:       if(i1 != 1 && TKresult[nres]!= k)
                   8593:        continue;
                   8594:       fprintf(ficresvpl,"\n#****** ");
                   8595:       printf("\n#****** ");
                   8596:       fprintf(ficlog,"\n#****** ");
                   8597:       for(j=1;j<=cptcoveff;j++) {
                   8598:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8599:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8600:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8601:       }
                   8602:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8603:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8604:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8605:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8606:       }        
                   8607:       fprintf(ficresvpl,"******\n");
                   8608:       printf("******\n");
                   8609:       fprintf(ficlog,"******\n");
                   8610:       
                   8611:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8612:       oldm=oldms;savm=savms;
                   8613:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8614:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8615:       /*}*/
                   8616:     }
                   8617:     
                   8618:     fclose(ficresvpl);
1.288     brouard  8619:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8620:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8621: 
                   8622:  }
                   8623: /* Variance of back prevalence: varbprlim */
                   8624:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8625:       /*------- Variance of back (stable) prevalence------*/
                   8626: 
                   8627:    char fileresvbl[FILENAMELENGTH];  
                   8628:    FILE  *ficresvbl;
                   8629: 
                   8630:    double **oldm, **savm;
                   8631:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8632:    int i1, k, nres, j ;
                   8633: 
                   8634:    strcpy(fileresvbl,"VBL_");
                   8635:    strcat(fileresvbl,fileresu);
                   8636:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8637:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8638:      exit(0);
                   8639:    }
                   8640:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8641:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8642:    
                   8643:    
                   8644:    i1=pow(2,cptcoveff);
                   8645:    if (cptcovn < 1){i1=1;}
                   8646:    
                   8647:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8648:      for(k=1; k<=i1;k++){
                   8649:        if(i1 != 1 && TKresult[nres]!= k)
                   8650:         continue;
                   8651:        fprintf(ficresvbl,"\n#****** ");
                   8652:        printf("\n#****** ");
                   8653:        fprintf(ficlog,"\n#****** ");
                   8654:        for(j=1;j<=cptcoveff;j++) {
                   8655:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8656:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8657:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8658:        }
                   8659:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8660:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8661:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8662:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8663:        }
                   8664:        fprintf(ficresvbl,"******\n");
                   8665:        printf("******\n");
                   8666:        fprintf(ficlog,"******\n");
                   8667:        
                   8668:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8669:        oldm=oldms;savm=savms;
                   8670:        
                   8671:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8672:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8673:        /*}*/
                   8674:      }
                   8675:    
                   8676:    fclose(ficresvbl);
                   8677:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8678:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8679: 
                   8680:  } /* End of varbprlim */
                   8681: 
1.126     brouard  8682: /************** Forecasting *****not tested NB*************/
1.227     brouard  8683: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8684:   
1.227     brouard  8685: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8686: /*   int *popage; */
                   8687: /*   double calagedatem, agelim, kk1, kk2; */
                   8688: /*   double *popeffectif,*popcount; */
                   8689: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8690: /*   /\* double ***mobaverage; *\/ */
                   8691: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8692: 
1.227     brouard  8693: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8694: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8695: /*   agelim=AGESUP; */
                   8696: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8697:   
1.227     brouard  8698: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8699:   
                   8700:   
1.227     brouard  8701: /*   strcpy(filerespop,"POP_");  */
                   8702: /*   strcat(filerespop,fileresu); */
                   8703: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8704: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8705: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8706: /*   } */
                   8707: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8708: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8709: 
1.227     brouard  8710: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8711: 
1.227     brouard  8712: /*   /\* if (mobilav!=0) { *\/ */
                   8713: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8714: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8715: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8716: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8717: /*   /\*   } *\/ */
                   8718: /*   /\* } *\/ */
1.126     brouard  8719: 
1.227     brouard  8720: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8721: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8722:   
1.227     brouard  8723: /*   agelim=AGESUP; */
1.126     brouard  8724:   
1.227     brouard  8725: /*   hstepm=1; */
                   8726: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8727:        
1.227     brouard  8728: /*   if (popforecast==1) { */
                   8729: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8730: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8731: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8732: /*     }  */
                   8733: /*     popage=ivector(0,AGESUP); */
                   8734: /*     popeffectif=vector(0,AGESUP); */
                   8735: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8736:     
1.227     brouard  8737: /*     i=1;    */
                   8738: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8739:     
1.227     brouard  8740: /*     imx=i; */
                   8741: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8742: /*   } */
1.218     brouard  8743:   
1.227     brouard  8744: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8745: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8746: /*       k=k+1; */
                   8747: /*       fprintf(ficrespop,"\n#******"); */
                   8748: /*       for(j=1;j<=cptcoveff;j++) { */
                   8749: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8750: /*       } */
                   8751: /*       fprintf(ficrespop,"******\n"); */
                   8752: /*       fprintf(ficrespop,"# Age"); */
                   8753: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8754: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8755:       
1.227     brouard  8756: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8757: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8758:        
1.227     brouard  8759: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8760: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8761: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8762:          
1.227     brouard  8763: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8764: /*       oldm=oldms;savm=savms; */
                   8765: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8766:          
1.227     brouard  8767: /*       for (h=0; h<=nhstepm; h++){ */
                   8768: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8769: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8770: /*         }  */
                   8771: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8772: /*           kk1=0.;kk2=0; */
                   8773: /*           for(i=1; i<=nlstate;i++) {               */
                   8774: /*             if (mobilav==1)  */
                   8775: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8776: /*             else { */
                   8777: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8778: /*             } */
                   8779: /*           } */
                   8780: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8781: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8782: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8783: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8784: /*           } */
                   8785: /*         } */
                   8786: /*         for(i=1; i<=nlstate;i++){ */
                   8787: /*           kk1=0.; */
                   8788: /*           for(j=1; j<=nlstate;j++){ */
                   8789: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8790: /*           } */
                   8791: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8792: /*         } */
1.218     brouard  8793:            
1.227     brouard  8794: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8795: /*           for(j=1; j<=nlstate;j++)  */
                   8796: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8797: /*       } */
                   8798: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8799: /*     } */
                   8800: /*       } */
1.218     brouard  8801:       
1.227     brouard  8802: /*       /\******\/ */
1.218     brouard  8803:       
1.227     brouard  8804: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8805: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8806: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8807: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8808: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8809:          
1.227     brouard  8810: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8811: /*       oldm=oldms;savm=savms; */
                   8812: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8813: /*       for (h=0; h<=nhstepm; h++){ */
                   8814: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8815: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8816: /*         }  */
                   8817: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8818: /*           kk1=0.;kk2=0; */
                   8819: /*           for(i=1; i<=nlstate;i++) {               */
                   8820: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8821: /*           } */
                   8822: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8823: /*         } */
                   8824: /*       } */
                   8825: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8826: /*     } */
                   8827: /*       } */
                   8828: /*     }  */
                   8829: /*   } */
1.218     brouard  8830:   
1.227     brouard  8831: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8832:   
1.227     brouard  8833: /*   if (popforecast==1) { */
                   8834: /*     free_ivector(popage,0,AGESUP); */
                   8835: /*     free_vector(popeffectif,0,AGESUP); */
                   8836: /*     free_vector(popcount,0,AGESUP); */
                   8837: /*   } */
                   8838: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8839: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8840: /*   fclose(ficrespop); */
                   8841: /* } /\* End of popforecast *\/ */
1.218     brouard  8842:  
1.126     brouard  8843: int fileappend(FILE *fichier, char *optionfich)
                   8844: {
                   8845:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8846:     printf("Problem with file: %s\n", optionfich);
                   8847:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8848:     return (0);
                   8849:   }
                   8850:   fflush(fichier);
                   8851:   return (1);
                   8852: }
                   8853: 
                   8854: 
                   8855: /**************** function prwizard **********************/
                   8856: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8857: {
                   8858: 
                   8859:   /* Wizard to print covariance matrix template */
                   8860: 
1.164     brouard  8861:   char ca[32], cb[32];
                   8862:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8863:   int numlinepar;
                   8864: 
                   8865:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8866:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8867:   for(i=1; i <=nlstate; i++){
                   8868:     jj=0;
                   8869:     for(j=1; j <=nlstate+ndeath; j++){
                   8870:       if(j==i) continue;
                   8871:       jj++;
                   8872:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8873:       printf("%1d%1d",i,j);
                   8874:       fprintf(ficparo,"%1d%1d",i,j);
                   8875:       for(k=1; k<=ncovmodel;k++){
                   8876:        /*        printf(" %lf",param[i][j][k]); */
                   8877:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8878:        printf(" 0.");
                   8879:        fprintf(ficparo," 0.");
                   8880:       }
                   8881:       printf("\n");
                   8882:       fprintf(ficparo,"\n");
                   8883:     }
                   8884:   }
                   8885:   printf("# Scales (for hessian or gradient estimation)\n");
                   8886:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8887:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8888:   for(i=1; i <=nlstate; i++){
                   8889:     jj=0;
                   8890:     for(j=1; j <=nlstate+ndeath; j++){
                   8891:       if(j==i) continue;
                   8892:       jj++;
                   8893:       fprintf(ficparo,"%1d%1d",i,j);
                   8894:       printf("%1d%1d",i,j);
                   8895:       fflush(stdout);
                   8896:       for(k=1; k<=ncovmodel;k++){
                   8897:        /*      printf(" %le",delti3[i][j][k]); */
                   8898:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8899:        printf(" 0.");
                   8900:        fprintf(ficparo," 0.");
                   8901:       }
                   8902:       numlinepar++;
                   8903:       printf("\n");
                   8904:       fprintf(ficparo,"\n");
                   8905:     }
                   8906:   }
                   8907:   printf("# Covariance matrix\n");
                   8908: /* # 121 Var(a12)\n\ */
                   8909: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8910: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8911: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8912: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8913: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8914: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8915: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8916:   fflush(stdout);
                   8917:   fprintf(ficparo,"# Covariance matrix\n");
                   8918:   /* # 121 Var(a12)\n\ */
                   8919:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8920:   /* #   ...\n\ */
                   8921:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8922:   
                   8923:   for(itimes=1;itimes<=2;itimes++){
                   8924:     jj=0;
                   8925:     for(i=1; i <=nlstate; i++){
                   8926:       for(j=1; j <=nlstate+ndeath; j++){
                   8927:        if(j==i) continue;
                   8928:        for(k=1; k<=ncovmodel;k++){
                   8929:          jj++;
                   8930:          ca[0]= k+'a'-1;ca[1]='\0';
                   8931:          if(itimes==1){
                   8932:            printf("#%1d%1d%d",i,j,k);
                   8933:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8934:          }else{
                   8935:            printf("%1d%1d%d",i,j,k);
                   8936:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8937:            /*  printf(" %.5le",matcov[i][j]); */
                   8938:          }
                   8939:          ll=0;
                   8940:          for(li=1;li <=nlstate; li++){
                   8941:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8942:              if(lj==li) continue;
                   8943:              for(lk=1;lk<=ncovmodel;lk++){
                   8944:                ll++;
                   8945:                if(ll<=jj){
                   8946:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8947:                  if(ll<jj){
                   8948:                    if(itimes==1){
                   8949:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8950:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8951:                    }else{
                   8952:                      printf(" 0.");
                   8953:                      fprintf(ficparo," 0.");
                   8954:                    }
                   8955:                  }else{
                   8956:                    if(itimes==1){
                   8957:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8958:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8959:                    }else{
                   8960:                      printf(" 0.");
                   8961:                      fprintf(ficparo," 0.");
                   8962:                    }
                   8963:                  }
                   8964:                }
                   8965:              } /* end lk */
                   8966:            } /* end lj */
                   8967:          } /* end li */
                   8968:          printf("\n");
                   8969:          fprintf(ficparo,"\n");
                   8970:          numlinepar++;
                   8971:        } /* end k*/
                   8972:       } /*end j */
                   8973:     } /* end i */
                   8974:   } /* end itimes */
                   8975: 
                   8976: } /* end of prwizard */
                   8977: /******************* Gompertz Likelihood ******************************/
                   8978: double gompertz(double x[])
                   8979: { 
                   8980:   double A,B,L=0.0,sump=0.,num=0.;
                   8981:   int i,n=0; /* n is the size of the sample */
                   8982: 
1.220     brouard  8983:   for (i=1;i<=imx ; i++) {
1.126     brouard  8984:     sump=sump+weight[i];
                   8985:     /*    sump=sump+1;*/
                   8986:     num=num+1;
                   8987:   }
                   8988:  
                   8989:  
                   8990:   /* for (i=0; i<=imx; i++) 
                   8991:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   8992: 
                   8993:   for (i=1;i<=imx ; i++)
                   8994:     {
                   8995:       if (cens[i] == 1 && wav[i]>1)
                   8996:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   8997:       
                   8998:       if (cens[i] == 0 && wav[i]>1)
                   8999:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   9000:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   9001:       
                   9002:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9003:       if (wav[i] > 1 ) { /* ??? */
                   9004:        L=L+A*weight[i];
                   9005:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9006:       }
                   9007:     }
                   9008: 
                   9009:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9010:  
                   9011:   return -2*L*num/sump;
                   9012: }
                   9013: 
1.136     brouard  9014: #ifdef GSL
                   9015: /******************* Gompertz_f Likelihood ******************************/
                   9016: double gompertz_f(const gsl_vector *v, void *params)
                   9017: { 
                   9018:   double A,B,LL=0.0,sump=0.,num=0.;
                   9019:   double *x= (double *) v->data;
                   9020:   int i,n=0; /* n is the size of the sample */
                   9021: 
                   9022:   for (i=0;i<=imx-1 ; i++) {
                   9023:     sump=sump+weight[i];
                   9024:     /*    sump=sump+1;*/
                   9025:     num=num+1;
                   9026:   }
                   9027:  
                   9028:  
                   9029:   /* for (i=0; i<=imx; i++) 
                   9030:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9031:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9032:   for (i=1;i<=imx ; i++)
                   9033:     {
                   9034:       if (cens[i] == 1 && wav[i]>1)
                   9035:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9036:       
                   9037:       if (cens[i] == 0 && wav[i]>1)
                   9038:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9039:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9040:       
                   9041:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9042:       if (wav[i] > 1 ) { /* ??? */
                   9043:        LL=LL+A*weight[i];
                   9044:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9045:       }
                   9046:     }
                   9047: 
                   9048:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9049:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9050:  
                   9051:   return -2*LL*num/sump;
                   9052: }
                   9053: #endif
                   9054: 
1.126     brouard  9055: /******************* Printing html file ***********/
1.201     brouard  9056: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9057:                  int lastpass, int stepm, int weightopt, char model[],\
                   9058:                  int imx,  double p[],double **matcov,double agemortsup){
                   9059:   int i,k;
                   9060: 
                   9061:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9062:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9063:   for (i=1;i<=2;i++) 
                   9064:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9065:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9066:   fprintf(fichtm,"</ul>");
                   9067: 
                   9068: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9069: 
                   9070:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9071: 
                   9072:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9073:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9074: 
                   9075:  
                   9076:   fflush(fichtm);
                   9077: }
                   9078: 
                   9079: /******************* Gnuplot file **************/
1.201     brouard  9080: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9081: 
                   9082:   char dirfileres[132],optfileres[132];
1.164     brouard  9083: 
1.126     brouard  9084:   int ng;
                   9085: 
                   9086: 
                   9087:   /*#ifdef windows */
                   9088:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9089:     /*#endif */
                   9090: 
                   9091: 
                   9092:   strcpy(dirfileres,optionfilefiname);
                   9093:   strcpy(optfileres,"vpl");
1.199     brouard  9094:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9095:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9096:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9097:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9098:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9099: 
                   9100: } 
                   9101: 
1.136     brouard  9102: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9103: {
1.126     brouard  9104: 
1.136     brouard  9105:   /*-------- data file ----------*/
                   9106:   FILE *fic;
                   9107:   char dummy[]="                         ";
1.240     brouard  9108:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9109:   int lstra;
1.136     brouard  9110:   int linei, month, year,iout;
                   9111:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9112:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9113:   char *stratrunc;
1.223     brouard  9114: 
1.240     brouard  9115:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9116:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9117: 
1.240     brouard  9118:   for(v=1; v <=ncovcol;v++){
                   9119:     DummyV[v]=0;
                   9120:     FixedV[v]=0;
                   9121:   }
                   9122:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9123:     DummyV[v]=1;
                   9124:     FixedV[v]=0;
                   9125:   }
                   9126:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9127:     DummyV[v]=0;
                   9128:     FixedV[v]=1;
                   9129:   }
                   9130:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9131:     DummyV[v]=1;
                   9132:     FixedV[v]=1;
                   9133:   }
                   9134:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9135:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9136:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9137:   }
1.126     brouard  9138: 
1.136     brouard  9139:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9140:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9141:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9142:   }
1.126     brouard  9143: 
1.136     brouard  9144:   i=1;
                   9145:   linei=0;
                   9146:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9147:     linei=linei+1;
                   9148:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9149:       if(line[j] == '\t')
                   9150:        line[j] = ' ';
                   9151:     }
                   9152:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9153:       ;
                   9154:     };
                   9155:     line[j+1]=0;  /* Trims blanks at end of line */
                   9156:     if(line[0]=='#'){
                   9157:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9158:       printf("Comment line\n%s\n",line);
                   9159:       continue;
                   9160:     }
                   9161:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9162:     strcpy(line, linetmp);
1.223     brouard  9163:     
                   9164:     /* Loops on waves */
                   9165:     for (j=maxwav;j>=1;j--){
                   9166:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9167:        cutv(stra, strb, line, ' '); 
                   9168:        if(strb[0]=='.') { /* Missing value */
                   9169:          lval=-1;
                   9170:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9171:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9172:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9173:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9174:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9175:            return 1;
                   9176:          }
                   9177:        }else{
                   9178:          errno=0;
                   9179:          /* what_kind_of_number(strb); */
                   9180:          dval=strtod(strb,&endptr); 
                   9181:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9182:          /* if(strb != endptr && *endptr == '\0') */
                   9183:          /*    dval=dlval; */
                   9184:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9185:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9186:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9187:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9188:            return 1;
                   9189:          }
                   9190:          cotqvar[j][iv][i]=dval; 
                   9191:          cotvar[j][ntv+iv][i]=dval; 
                   9192:        }
                   9193:        strcpy(line,stra);
1.223     brouard  9194:       }/* end loop ntqv */
1.225     brouard  9195:       
1.223     brouard  9196:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9197:        cutv(stra, strb, line, ' '); 
                   9198:        if(strb[0]=='.') { /* Missing value */
                   9199:          lval=-1;
                   9200:        }else{
                   9201:          errno=0;
                   9202:          lval=strtol(strb,&endptr,10); 
                   9203:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9204:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9205:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9206:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9207:            return 1;
                   9208:          }
                   9209:        }
                   9210:        if(lval <-1 || lval >1){
                   9211:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9212:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9213:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9214:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9215:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9216:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9217:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9218:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9219:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9220:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9221:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9222:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9223:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9224:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9225:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9226:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9227:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9228:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9229:          return 1;
                   9230:        }
                   9231:        cotvar[j][iv][i]=(double)(lval);
                   9232:        strcpy(line,stra);
1.223     brouard  9233:       }/* end loop ntv */
1.225     brouard  9234:       
1.223     brouard  9235:       /* Statuses  at wave */
1.137     brouard  9236:       cutv(stra, strb, line, ' '); 
1.223     brouard  9237:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9238:        lval=-1;
1.136     brouard  9239:       }else{
1.238     brouard  9240:        errno=0;
                   9241:        lval=strtol(strb,&endptr,10); 
                   9242:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9243:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9244:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9245:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9246:          return 1;
                   9247:        }
1.136     brouard  9248:       }
1.225     brouard  9249:       
1.136     brouard  9250:       s[j][i]=lval;
1.225     brouard  9251:       
1.223     brouard  9252:       /* Date of Interview */
1.136     brouard  9253:       strcpy(line,stra);
                   9254:       cutv(stra, strb,line,' ');
1.169     brouard  9255:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9256:       }
1.169     brouard  9257:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9258:        month=99;
                   9259:        year=9999;
1.136     brouard  9260:       }else{
1.225     brouard  9261:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9262:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9263:        return 1;
1.136     brouard  9264:       }
                   9265:       anint[j][i]= (double) year; 
                   9266:       mint[j][i]= (double)month; 
                   9267:       strcpy(line,stra);
1.223     brouard  9268:     } /* End loop on waves */
1.225     brouard  9269:     
1.223     brouard  9270:     /* Date of death */
1.136     brouard  9271:     cutv(stra, strb,line,' '); 
1.169     brouard  9272:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9273:     }
1.169     brouard  9274:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9275:       month=99;
                   9276:       year=9999;
                   9277:     }else{
1.141     brouard  9278:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9279:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9280:       return 1;
1.136     brouard  9281:     }
                   9282:     andc[i]=(double) year; 
                   9283:     moisdc[i]=(double) month; 
                   9284:     strcpy(line,stra);
                   9285:     
1.223     brouard  9286:     /* Date of birth */
1.136     brouard  9287:     cutv(stra, strb,line,' '); 
1.169     brouard  9288:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9289:     }
1.169     brouard  9290:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9291:       month=99;
                   9292:       year=9999;
                   9293:     }else{
1.141     brouard  9294:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9295:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9296:       return 1;
1.136     brouard  9297:     }
                   9298:     if (year==9999) {
1.141     brouard  9299:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9300:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9301:       return 1;
                   9302:       
1.136     brouard  9303:     }
                   9304:     annais[i]=(double)(year);
                   9305:     moisnais[i]=(double)(month); 
                   9306:     strcpy(line,stra);
1.225     brouard  9307:     
1.223     brouard  9308:     /* Sample weight */
1.136     brouard  9309:     cutv(stra, strb,line,' '); 
                   9310:     errno=0;
                   9311:     dval=strtod(strb,&endptr); 
                   9312:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9313:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9314:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9315:       fflush(ficlog);
                   9316:       return 1;
                   9317:     }
                   9318:     weight[i]=dval; 
                   9319:     strcpy(line,stra);
1.225     brouard  9320:     
1.223     brouard  9321:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9322:       cutv(stra, strb, line, ' '); 
                   9323:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9324:        lval=-1;
1.223     brouard  9325:       }else{
1.225     brouard  9326:        errno=0;
                   9327:        /* what_kind_of_number(strb); */
                   9328:        dval=strtod(strb,&endptr);
                   9329:        /* if(strb != endptr && *endptr == '\0') */
                   9330:        /*   dval=dlval; */
                   9331:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9332:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9333:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9334:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9335:          return 1;
                   9336:        }
                   9337:        coqvar[iv][i]=dval; 
1.226     brouard  9338:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9339:       }
                   9340:       strcpy(line,stra);
                   9341:     }/* end loop nqv */
1.136     brouard  9342:     
1.223     brouard  9343:     /* Covariate values */
1.136     brouard  9344:     for (j=ncovcol;j>=1;j--){
                   9345:       cutv(stra, strb,line,' '); 
1.223     brouard  9346:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9347:        lval=-1;
1.136     brouard  9348:       }else{
1.225     brouard  9349:        errno=0;
                   9350:        lval=strtol(strb,&endptr,10); 
                   9351:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9352:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9353:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9354:          return 1;
                   9355:        }
1.136     brouard  9356:       }
                   9357:       if(lval <-1 || lval >1){
1.225     brouard  9358:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9359:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9360:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9361:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9362:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9363:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9364:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9365:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9366:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9367:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9368:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9369:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9370:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9371:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9372:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9373:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9374:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9375:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9376:        return 1;
1.136     brouard  9377:       }
                   9378:       covar[j][i]=(double)(lval);
                   9379:       strcpy(line,stra);
                   9380:     }  
                   9381:     lstra=strlen(stra);
1.225     brouard  9382:     
1.136     brouard  9383:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9384:       stratrunc = &(stra[lstra-9]);
                   9385:       num[i]=atol(stratrunc);
                   9386:     }
                   9387:     else
                   9388:       num[i]=atol(stra);
                   9389:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9390:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9391:     
                   9392:     i=i+1;
                   9393:   } /* End loop reading  data */
1.225     brouard  9394:   
1.136     brouard  9395:   *imax=i-1; /* Number of individuals */
                   9396:   fclose(fic);
1.225     brouard  9397:   
1.136     brouard  9398:   return (0);
1.164     brouard  9399:   /* endread: */
1.225     brouard  9400:   printf("Exiting readdata: ");
                   9401:   fclose(fic);
                   9402:   return (1);
1.223     brouard  9403: }
1.126     brouard  9404: 
1.234     brouard  9405: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9406:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9407:   while (*p2 == ' ')
1.234     brouard  9408:     p2++; 
                   9409:   /* while ((*p1++ = *p2++) !=0) */
                   9410:   /*   ; */
                   9411:   /* do */
                   9412:   /*   while (*p2 == ' ') */
                   9413:   /*     p2++; */
                   9414:   /* while (*p1++ == *p2++); */
                   9415:   *stri=p2; 
1.145     brouard  9416: }
                   9417: 
1.235     brouard  9418: int decoderesult ( char resultline[], int nres)
1.230     brouard  9419: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9420: {
1.235     brouard  9421:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9422:   char resultsav[MAXLINE];
1.234     brouard  9423:   int resultmodel[MAXLINE];
                   9424:   int modelresult[MAXLINE];
1.230     brouard  9425:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9426: 
1.234     brouard  9427:   removefirstspace(&resultline);
1.233     brouard  9428:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9429: 
                   9430:   if (strstr(resultline,"v") !=0){
                   9431:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9432:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9433:     return 1;
                   9434:   }
                   9435:   trimbb(resultsav, resultline);
                   9436:   if (strlen(resultsav) >1){
                   9437:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9438:   }
1.253     brouard  9439:   if(j == 0){ /* Resultline but no = */
                   9440:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9441:     return (0);
                   9442:   }
                   9443:     
1.234     brouard  9444:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9445:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9446:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9447:   }
                   9448:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9449:     if(nbocc(resultsav,'=') >1){
                   9450:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9451:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9452:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9453:     }else
                   9454:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9455:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9456:     
1.230     brouard  9457:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9458:     Tvarsel[k]=atoi(strc);
                   9459:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9460:     /* cptcovsel++;     */
                   9461:     if (nbocc(stra,'=') >0)
                   9462:       strcpy(resultsav,stra); /* and analyzes it */
                   9463:   }
1.235     brouard  9464:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9465:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9466:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9467:       match=0;
1.236     brouard  9468:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9469:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9470:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9471:          match=1;
                   9472:          break;
                   9473:        }
                   9474:       }
                   9475:       if(match == 0){
                   9476:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9477:       }
                   9478:     }
                   9479:   }
1.235     brouard  9480:   /* Checking for missing or useless values in comparison of current model needs */
                   9481:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9482:     match=0;
1.235     brouard  9483:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9484:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9485:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9486:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9487:          ++match;
                   9488:        }
                   9489:       }
                   9490:     }
                   9491:     if(match == 0){
                   9492:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9493:     }else if(match > 1){
                   9494:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9495:     }
                   9496:   }
1.235     brouard  9497:       
1.234     brouard  9498:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9499:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9500:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9501:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9502:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9503:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9504:   /*    1 0 0 0 */
                   9505:   /*    2 1 0 0 */
                   9506:   /*    3 0 1 0 */ 
                   9507:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9508:   /*    5 0 0 1 */
                   9509:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9510:   /*    7 0 1 1 */
                   9511:   /*    8 1 1 1 */
1.237     brouard  9512:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9513:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9514:   /* V5*age V5 known which value for nres?  */
                   9515:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9516:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9517:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9518:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9519:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9520:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9521:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9522:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9523:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9524:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9525:       k4++;;
                   9526:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9527:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9528:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9529:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9530:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9531:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9532:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9533:       k4q++;;
                   9534:     }
                   9535:   }
1.234     brouard  9536:   
1.235     brouard  9537:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9538:   return (0);
                   9539: }
1.235     brouard  9540: 
1.230     brouard  9541: int decodemodel( char model[], int lastobs)
                   9542:  /**< This routine decodes the model and returns:
1.224     brouard  9543:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9544:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9545:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9546:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9547:        * - cptcovage number of covariates with age*products =2
                   9548:        * - cptcovs number of simple covariates
                   9549:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9550:        *     which is a new column after the 9 (ncovcol) variables. 
                   9551:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9552:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9553:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9554:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9555:        */
1.136     brouard  9556: {
1.238     brouard  9557:   int i, j, k, ks, v;
1.227     brouard  9558:   int  j1, k1, k2, k3, k4;
1.136     brouard  9559:   char modelsav[80];
1.145     brouard  9560:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9561:   char *strpt;
1.136     brouard  9562: 
1.145     brouard  9563:   /*removespace(model);*/
1.136     brouard  9564:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9565:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9566:     if (strstr(model,"AGE") !=0){
1.192     brouard  9567:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9568:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9569:       return 1;
                   9570:     }
1.141     brouard  9571:     if (strstr(model,"v") !=0){
                   9572:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9573:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9574:       return 1;
                   9575:     }
1.187     brouard  9576:     strcpy(modelsav,model); 
                   9577:     if ((strpt=strstr(model,"age*age")) !=0){
                   9578:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9579:       if(strpt != model){
1.234     brouard  9580:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9581:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9582:  corresponding column of parameters.\n",model);
1.234     brouard  9583:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9584:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9585:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9586:        return 1;
1.225     brouard  9587:       }
1.187     brouard  9588:       nagesqr=1;
                   9589:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9590:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9591:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9592:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9593:       else 
1.234     brouard  9594:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9595:     }else
                   9596:       nagesqr=0;
                   9597:     if (strlen(modelsav) >1){
                   9598:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9599:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9600:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9601:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9602:                     * cst, age and age*age 
                   9603:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9604:       /* including age products which are counted in cptcovage.
                   9605:        * but the covariates which are products must be treated 
                   9606:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9607:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9608:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9609:       
                   9610:       
1.187     brouard  9611:       /*   Design
                   9612:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9613:        *  <          ncovcol=8                >
                   9614:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9615:        *   k=  1    2      3       4     5       6      7        8
                   9616:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9617:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9618:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9619:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9620:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9621:        *  Tage[++cptcovage]=k
                   9622:        *       if products, new covar are created after ncovcol with k1
                   9623:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9624:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9625:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9626:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9627:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9628:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9629:        *  <          ncovcol=8                >
                   9630:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9631:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9632:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9633:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9634:        * p Tprod[1]@2={                         6, 5}
                   9635:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9636:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9637:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9638:        *How to reorganize?
                   9639:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9640:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9641:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9642:        * Struct []
                   9643:        */
1.225     brouard  9644:       
1.187     brouard  9645:       /* This loop fills the array Tvar from the string 'model'.*/
                   9646:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9647:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9648:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9649:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9650:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9651:       /*       k=1 Tvar[1]=2 (from V2) */
                   9652:       /*       k=5 Tvar[5] */
                   9653:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9654:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9655:       /*       } */
1.198     brouard  9656:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9657:       /*
                   9658:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9659:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9660:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9661:       }
1.187     brouard  9662:       cptcovage=0;
                   9663:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9664:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9665:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9666:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9667:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9668:        /*scanf("%d",i);*/
                   9669:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9670:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9671:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9672:            /* covar is not filled and then is empty */
                   9673:            cptcovprod--;
                   9674:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9675:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9676:            Typevar[k]=1;  /* 1 for age product */
                   9677:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9678:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9679:            /*printf("stre=%s ", stre);*/
                   9680:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9681:            cptcovprod--;
                   9682:            cutl(stre,strb,strc,'V');
                   9683:            Tvar[k]=atoi(stre);
                   9684:            Typevar[k]=1;  /* 1 for age product */
                   9685:            cptcovage++;
                   9686:            Tage[cptcovage]=k;
                   9687:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9688:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9689:            cptcovn++;
                   9690:            cptcovprodnoage++;k1++;
                   9691:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9692:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9693:                                                because this model-covariate is a construction we invent a new column
                   9694:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9695:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9696:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9697:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9698:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9699:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9700:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9701:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9702:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9703:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9704:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9705:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9706:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9707:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9708:            for (i=1; i<=lastobs;i++){
                   9709:              /* Computes the new covariate which is a product of
                   9710:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9711:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9712:            }
                   9713:          } /* End age is not in the model */
                   9714:        } /* End if model includes a product */
                   9715:        else { /* no more sum */
                   9716:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9717:          /*  scanf("%d",i);*/
                   9718:          cutl(strd,strc,strb,'V');
                   9719:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9720:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9721:          Tvar[k]=atoi(strd);
                   9722:          Typevar[k]=0;  /* 0 for simple covariates */
                   9723:        }
                   9724:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9725:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9726:                                  scanf("%d",i);*/
1.187     brouard  9727:       } /* end of loop + on total covariates */
                   9728:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9729:   } /* end if strlen(model == 0) */
1.136     brouard  9730:   
                   9731:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9732:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9733:   
1.136     brouard  9734:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9735:      printf("cptcovprod=%d ", cptcovprod);
                   9736:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9737:      scanf("%d ",i);*/
                   9738: 
                   9739: 
1.230     brouard  9740: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9741:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9742: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9743:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9744:    k =           1    2   3     4       5       6      7      8        9
                   9745:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9746:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9747:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9748:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9749:          Tmodelind[combination of covar]=k;
1.225     brouard  9750: */  
                   9751: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9752:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9753:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9754:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9755:   printf("Model=%s\n\
                   9756: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9757: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9758: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9759:   fprintf(ficlog,"Model=%s\n\
                   9760: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9761: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9762: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9763:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9764:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9765:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9766:       Fixed[k]= 0;
                   9767:       Dummy[k]= 0;
1.225     brouard  9768:       ncoveff++;
1.232     brouard  9769:       ncovf++;
1.234     brouard  9770:       nsd++;
                   9771:       modell[k].maintype= FTYPE;
                   9772:       TvarsD[nsd]=Tvar[k];
                   9773:       TvarsDind[nsd]=k;
                   9774:       TvarF[ncovf]=Tvar[k];
                   9775:       TvarFind[ncovf]=k;
                   9776:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9777:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9778:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9779:       Fixed[k]= 0;
                   9780:       Dummy[k]= 0;
                   9781:       ncoveff++;
                   9782:       ncovf++;
                   9783:       modell[k].maintype= FTYPE;
                   9784:       TvarF[ncovf]=Tvar[k];
                   9785:       TvarFind[ncovf]=k;
1.230     brouard  9786:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9787:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9788:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9789:       Fixed[k]= 0;
                   9790:       Dummy[k]= 1;
1.230     brouard  9791:       nqfveff++;
1.234     brouard  9792:       modell[k].maintype= FTYPE;
                   9793:       modell[k].subtype= FQ;
                   9794:       nsq++;
                   9795:       TvarsQ[nsq]=Tvar[k];
                   9796:       TvarsQind[nsq]=k;
1.232     brouard  9797:       ncovf++;
1.234     brouard  9798:       TvarF[ncovf]=Tvar[k];
                   9799:       TvarFind[ncovf]=k;
1.231     brouard  9800:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9801:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9802:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9803:       Fixed[k]= 1;
                   9804:       Dummy[k]= 0;
1.225     brouard  9805:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9806:       modell[k].maintype= VTYPE;
                   9807:       modell[k].subtype= VD;
                   9808:       nsd++;
                   9809:       TvarsD[nsd]=Tvar[k];
                   9810:       TvarsDind[nsd]=k;
                   9811:       ncovv++; /* Only simple time varying variables */
                   9812:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9813:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9814:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9815:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9816:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9817:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9818:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9819:       Fixed[k]= 1;
                   9820:       Dummy[k]= 1;
                   9821:       nqtveff++;
                   9822:       modell[k].maintype= VTYPE;
                   9823:       modell[k].subtype= VQ;
                   9824:       ncovv++; /* Only simple time varying variables */
                   9825:       nsq++;
                   9826:       TvarsQ[nsq]=Tvar[k];
                   9827:       TvarsQind[nsq]=k;
                   9828:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9829:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9830:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9831:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9832:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9833:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9834:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9835:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9836:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9837:       ncova++;
                   9838:       TvarA[ncova]=Tvar[k];
                   9839:       TvarAind[ncova]=k;
1.231     brouard  9840:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9841:        Fixed[k]= 2;
                   9842:        Dummy[k]= 2;
                   9843:        modell[k].maintype= ATYPE;
                   9844:        modell[k].subtype= APFD;
                   9845:        /* ncoveff++; */
1.227     brouard  9846:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9847:        Fixed[k]= 2;
                   9848:        Dummy[k]= 3;
                   9849:        modell[k].maintype= ATYPE;
                   9850:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9851:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9852:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9853:        Fixed[k]= 3;
                   9854:        Dummy[k]= 2;
                   9855:        modell[k].maintype= ATYPE;
                   9856:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9857:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9858:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9859:        Fixed[k]= 3;
                   9860:        Dummy[k]= 3;
                   9861:        modell[k].maintype= ATYPE;
                   9862:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9863:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9864:       }
                   9865:     }else if (Typevar[k] == 2) {  /* product without age */
                   9866:       k1=Tposprod[k];
                   9867:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9868:        if(Tvard[k1][2] <=ncovcol){
                   9869:          Fixed[k]= 1;
                   9870:          Dummy[k]= 0;
                   9871:          modell[k].maintype= FTYPE;
                   9872:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9873:          ncovf++; /* Fixed variables without age */
                   9874:          TvarF[ncovf]=Tvar[k];
                   9875:          TvarFind[ncovf]=k;
                   9876:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9877:          Fixed[k]= 0;  /* or 2 ?*/
                   9878:          Dummy[k]= 1;
                   9879:          modell[k].maintype= FTYPE;
                   9880:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9881:          ncovf++; /* Varying variables without age */
                   9882:          TvarF[ncovf]=Tvar[k];
                   9883:          TvarFind[ncovf]=k;
                   9884:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9885:          Fixed[k]= 1;
                   9886:          Dummy[k]= 0;
                   9887:          modell[k].maintype= VTYPE;
                   9888:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9889:          ncovv++; /* Varying variables without age */
                   9890:          TvarV[ncovv]=Tvar[k];
                   9891:          TvarVind[ncovv]=k;
                   9892:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9893:          Fixed[k]= 1;
                   9894:          Dummy[k]= 1;
                   9895:          modell[k].maintype= VTYPE;
                   9896:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9897:          ncovv++; /* Varying variables without age */
                   9898:          TvarV[ncovv]=Tvar[k];
                   9899:          TvarVind[ncovv]=k;
                   9900:        }
1.227     brouard  9901:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9902:        if(Tvard[k1][2] <=ncovcol){
                   9903:          Fixed[k]= 0;  /* or 2 ?*/
                   9904:          Dummy[k]= 1;
                   9905:          modell[k].maintype= FTYPE;
                   9906:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9907:          ncovf++; /* Fixed variables without age */
                   9908:          TvarF[ncovf]=Tvar[k];
                   9909:          TvarFind[ncovf]=k;
                   9910:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9911:          Fixed[k]= 1;
                   9912:          Dummy[k]= 1;
                   9913:          modell[k].maintype= VTYPE;
                   9914:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9915:          ncovv++; /* Varying variables without age */
                   9916:          TvarV[ncovv]=Tvar[k];
                   9917:          TvarVind[ncovv]=k;
                   9918:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9919:          Fixed[k]= 1;
                   9920:          Dummy[k]= 1;
                   9921:          modell[k].maintype= VTYPE;
                   9922:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9923:          ncovv++; /* Varying variables without age */
                   9924:          TvarV[ncovv]=Tvar[k];
                   9925:          TvarVind[ncovv]=k;
                   9926:          ncovv++; /* Varying variables without age */
                   9927:          TvarV[ncovv]=Tvar[k];
                   9928:          TvarVind[ncovv]=k;
                   9929:        }
1.227     brouard  9930:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9931:        if(Tvard[k1][2] <=ncovcol){
                   9932:          Fixed[k]= 1;
                   9933:          Dummy[k]= 1;
                   9934:          modell[k].maintype= VTYPE;
                   9935:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9936:          ncovv++; /* Varying variables without age */
                   9937:          TvarV[ncovv]=Tvar[k];
                   9938:          TvarVind[ncovv]=k;
                   9939:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9940:          Fixed[k]= 1;
                   9941:          Dummy[k]= 1;
                   9942:          modell[k].maintype= VTYPE;
                   9943:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9944:          ncovv++; /* Varying variables without age */
                   9945:          TvarV[ncovv]=Tvar[k];
                   9946:          TvarVind[ncovv]=k;
                   9947:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9948:          Fixed[k]= 1;
                   9949:          Dummy[k]= 0;
                   9950:          modell[k].maintype= VTYPE;
                   9951:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9952:          ncovv++; /* Varying variables without age */
                   9953:          TvarV[ncovv]=Tvar[k];
                   9954:          TvarVind[ncovv]=k;
                   9955:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9956:          Fixed[k]= 1;
                   9957:          Dummy[k]= 1;
                   9958:          modell[k].maintype= VTYPE;
                   9959:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9960:          ncovv++; /* Varying variables without age */
                   9961:          TvarV[ncovv]=Tvar[k];
                   9962:          TvarVind[ncovv]=k;
                   9963:        }
1.227     brouard  9964:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9965:        if(Tvard[k1][2] <=ncovcol){
                   9966:          Fixed[k]= 1;
                   9967:          Dummy[k]= 1;
                   9968:          modell[k].maintype= VTYPE;
                   9969:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9970:          ncovv++; /* Varying variables without age */
                   9971:          TvarV[ncovv]=Tvar[k];
                   9972:          TvarVind[ncovv]=k;
                   9973:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9974:          Fixed[k]= 1;
                   9975:          Dummy[k]= 1;
                   9976:          modell[k].maintype= VTYPE;
                   9977:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9978:          ncovv++; /* Varying variables without age */
                   9979:          TvarV[ncovv]=Tvar[k];
                   9980:          TvarVind[ncovv]=k;
                   9981:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9982:          Fixed[k]= 1;
                   9983:          Dummy[k]= 1;
                   9984:          modell[k].maintype= VTYPE;
                   9985:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9986:          ncovv++; /* Varying variables without age */
                   9987:          TvarV[ncovv]=Tvar[k];
                   9988:          TvarVind[ncovv]=k;
                   9989:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9990:          Fixed[k]= 1;
                   9991:          Dummy[k]= 1;
                   9992:          modell[k].maintype= VTYPE;
                   9993:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   9994:          ncovv++; /* Varying variables without age */
                   9995:          TvarV[ncovv]=Tvar[k];
                   9996:          TvarVind[ncovv]=k;
                   9997:        }
1.227     brouard  9998:       }else{
1.240     brouard  9999:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10000:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10001:       } /*end k1*/
1.225     brouard  10002:     }else{
1.226     brouard  10003:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10004:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10005:     }
1.227     brouard  10006:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10007:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10008:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10009:   }
                   10010:   /* Searching for doublons in the model */
                   10011:   for(k1=1; k1<= cptcovt;k1++){
                   10012:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10013:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10014:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10015:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10016:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10017:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10018:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10019:            return(1);
                   10020:          }
                   10021:        }else if (Typevar[k1] ==2){
                   10022:          k3=Tposprod[k1];
                   10023:          k4=Tposprod[k2];
                   10024:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10025:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10026:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10027:            return(1);
                   10028:          }
                   10029:        }
1.227     brouard  10030:       }
                   10031:     }
1.225     brouard  10032:   }
                   10033:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10034:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10035:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10036:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10037:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10038:   /*endread:*/
1.225     brouard  10039:   printf("Exiting decodemodel: ");
                   10040:   return (1);
1.136     brouard  10041: }
                   10042: 
1.169     brouard  10043: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10044: {/* Check ages at death */
1.136     brouard  10045:   int i, m;
1.218     brouard  10046:   int firstone=0;
                   10047:   
1.136     brouard  10048:   for (i=1; i<=imx; i++) {
                   10049:     for(m=2; (m<= maxwav); m++) {
                   10050:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10051:        anint[m][i]=9999;
1.216     brouard  10052:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10053:          s[m][i]=-1;
1.136     brouard  10054:       }
                   10055:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10056:        *nberr = *nberr + 1;
1.218     brouard  10057:        if(firstone == 0){
                   10058:          firstone=1;
1.260     brouard  10059:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10060:        }
1.262     brouard  10061:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10062:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10063:       }
                   10064:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10065:        (*nberr)++;
1.259     brouard  10066:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10067:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10068:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10069:       }
                   10070:     }
                   10071:   }
                   10072: 
                   10073:   for (i=1; i<=imx; i++)  {
                   10074:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10075:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10076:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10077:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10078:          if(agedc[i]>0){
                   10079:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10080:              agev[m][i]=agedc[i];
1.214     brouard  10081:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10082:            }else {
1.136     brouard  10083:              if ((int)andc[i]!=9999){
                   10084:                nbwarn++;
                   10085:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10086:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10087:                agev[m][i]=-1;
                   10088:              }
                   10089:            }
1.169     brouard  10090:          } /* agedc > 0 */
1.214     brouard  10091:        } /* end if */
1.136     brouard  10092:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10093:                                 years but with the precision of a month */
                   10094:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10095:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10096:            agev[m][i]=1;
                   10097:          else if(agev[m][i] < *agemin){ 
                   10098:            *agemin=agev[m][i];
                   10099:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10100:          }
                   10101:          else if(agev[m][i] >*agemax){
                   10102:            *agemax=agev[m][i];
1.156     brouard  10103:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10104:          }
                   10105:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10106:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10107:        } /* en if 9*/
1.136     brouard  10108:        else { /* =9 */
1.214     brouard  10109:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10110:          agev[m][i]=1;
                   10111:          s[m][i]=-1;
                   10112:        }
                   10113:       }
1.214     brouard  10114:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10115:        agev[m][i]=1;
1.214     brouard  10116:       else{
                   10117:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10118:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10119:        agev[m][i]=0;
                   10120:       }
                   10121:     } /* End for lastpass */
                   10122:   }
1.136     brouard  10123:     
                   10124:   for (i=1; i<=imx; i++)  {
                   10125:     for(m=firstpass; (m<=lastpass); m++){
                   10126:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10127:        (*nberr)++;
1.136     brouard  10128:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10129:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10130:        return 1;
                   10131:       }
                   10132:     }
                   10133:   }
                   10134: 
                   10135:   /*for (i=1; i<=imx; i++){
                   10136:   for (m=firstpass; (m<lastpass); m++){
                   10137:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10138: }
                   10139: 
                   10140: }*/
                   10141: 
                   10142: 
1.139     brouard  10143:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10144:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10145: 
                   10146:   return (0);
1.164     brouard  10147:  /* endread:*/
1.136     brouard  10148:     printf("Exiting calandcheckages: ");
                   10149:     return (1);
                   10150: }
                   10151: 
1.172     brouard  10152: #if defined(_MSC_VER)
                   10153: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10154: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10155: //#include "stdafx.h"
                   10156: //#include <stdio.h>
                   10157: //#include <tchar.h>
                   10158: //#include <windows.h>
                   10159: //#include <iostream>
                   10160: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10161: 
                   10162: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10163: 
                   10164: BOOL IsWow64()
                   10165: {
                   10166:        BOOL bIsWow64 = FALSE;
                   10167: 
                   10168:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10169:        //  (HANDLE, PBOOL);
                   10170: 
                   10171:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10172: 
                   10173:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10174:        const char funcName[] = "IsWow64Process";
                   10175:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10176:                GetProcAddress(module, funcName);
                   10177: 
                   10178:        if (NULL != fnIsWow64Process)
                   10179:        {
                   10180:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10181:                        &bIsWow64))
                   10182:                        //throw std::exception("Unknown error");
                   10183:                        printf("Unknown error\n");
                   10184:        }
                   10185:        return bIsWow64 != FALSE;
                   10186: }
                   10187: #endif
1.177     brouard  10188: 
1.191     brouard  10189: void syscompilerinfo(int logged)
1.167     brouard  10190:  {
                   10191:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10192:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10193:    /* /GS /W3 /Gy
                   10194:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10195:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10196:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10197:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10198:    */ 
                   10199:    /* 64 bits */
1.185     brouard  10200:    /*
                   10201:      /GS /W3 /Gy
                   10202:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10203:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10204:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10205:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10206:    /* Optimization are useless and O3 is slower than O2 */
                   10207:    /*
                   10208:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10209:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10210:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10211:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10212:    */
1.186     brouard  10213:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10214:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10215:       /PDB:"visual studio
                   10216:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10217:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10218:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10219:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10220:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10221:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10222:       uiAccess='false'"
                   10223:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10224:       /NOLOGO /TLBID:1
                   10225:    */
1.177     brouard  10226: #if defined __INTEL_COMPILER
1.178     brouard  10227: #if defined(__GNUC__)
                   10228:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10229: #endif
1.177     brouard  10230: #elif defined(__GNUC__) 
1.179     brouard  10231: #ifndef  __APPLE__
1.174     brouard  10232: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10233: #endif
1.177     brouard  10234:    struct utsname sysInfo;
1.178     brouard  10235:    int cross = CROSS;
                   10236:    if (cross){
                   10237:           printf("Cross-");
1.191     brouard  10238:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10239:    }
1.174     brouard  10240: #endif
                   10241: 
1.171     brouard  10242: #include <stdint.h>
1.178     brouard  10243: 
1.191     brouard  10244:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10245: #if defined(__clang__)
1.191     brouard  10246:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10247: #endif
                   10248: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10249:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10250: #endif
                   10251: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10252:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10253: #endif
                   10254: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10255:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10256: #endif
                   10257: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10258:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10259: #endif
                   10260: #if defined(_MSC_VER)
1.191     brouard  10261:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10262: #endif
                   10263: #if defined(__PGI)
1.191     brouard  10264:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10265: #endif
                   10266: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10267:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10268: #endif
1.191     brouard  10269:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10270:    
1.167     brouard  10271: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10272: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10273:     // Windows (x64 and x86)
1.191     brouard  10274:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10275: #elif __unix__ // all unices, not all compilers
                   10276:     // Unix
1.191     brouard  10277:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10278: #elif __linux__
                   10279:     // linux
1.191     brouard  10280:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10281: #elif __APPLE__
1.174     brouard  10282:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10283:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10284: #endif
                   10285: 
                   10286: /*  __MINGW32__          */
                   10287: /*  __CYGWIN__  */
                   10288: /* __MINGW64__  */
                   10289: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10290: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10291: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10292: /* _WIN64  // Defined for applications for Win64. */
                   10293: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10294: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10295: 
1.167     brouard  10296: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10297:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10298: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10299:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10300: #else
1.191     brouard  10301:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10302: #endif
                   10303: 
1.169     brouard  10304: #if defined(__GNUC__)
                   10305: # if defined(__GNUC_PATCHLEVEL__)
                   10306: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10307:                             + __GNUC_MINOR__ * 100 \
                   10308:                             + __GNUC_PATCHLEVEL__)
                   10309: # else
                   10310: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10311:                             + __GNUC_MINOR__ * 100)
                   10312: # endif
1.174     brouard  10313:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10314:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10315: 
                   10316:    if (uname(&sysInfo) != -1) {
                   10317:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10318:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10319:    }
                   10320:    else
                   10321:       perror("uname() error");
1.179     brouard  10322:    //#ifndef __INTEL_COMPILER 
                   10323: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10324:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10325:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10326: #endif
1.169     brouard  10327: #endif
1.172     brouard  10328: 
1.286     brouard  10329:    //   void main ()
1.172     brouard  10330:    //   {
1.169     brouard  10331: #if defined(_MSC_VER)
1.174     brouard  10332:    if (IsWow64()){
1.191     brouard  10333:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10334:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10335:    }
                   10336:    else{
1.191     brouard  10337:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10338:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10339:    }
1.172     brouard  10340:    //     printf("\nPress Enter to continue...");
                   10341:    //     getchar();
                   10342:    //   }
                   10343: 
1.169     brouard  10344: #endif
                   10345:    
1.167     brouard  10346: 
1.219     brouard  10347: }
1.136     brouard  10348: 
1.219     brouard  10349: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10350:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10351:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10352:   /* double ftolpl = 1.e-10; */
1.180     brouard  10353:   double age, agebase, agelim;
1.203     brouard  10354:   double tot;
1.180     brouard  10355: 
1.202     brouard  10356:   strcpy(filerespl,"PL_");
                   10357:   strcat(filerespl,fileresu);
                   10358:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10359:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10360:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10361:   }
1.288     brouard  10362:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10363:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10364:   pstamp(ficrespl);
1.288     brouard  10365:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10366:   fprintf(ficrespl,"#Age ");
                   10367:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10368:   fprintf(ficrespl,"\n");
1.180     brouard  10369:   
1.219     brouard  10370:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10371: 
1.219     brouard  10372:   agebase=ageminpar;
                   10373:   agelim=agemaxpar;
1.180     brouard  10374: 
1.227     brouard  10375:   /* i1=pow(2,ncoveff); */
1.234     brouard  10376:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10377:   if (cptcovn < 1){i1=1;}
1.180     brouard  10378: 
1.238     brouard  10379:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10380:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10381:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10382:        continue;
1.235     brouard  10383: 
1.238     brouard  10384:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10385:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10386:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10387:       /* k=k+1; */
                   10388:       /* to clean */
                   10389:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10390:       fprintf(ficrespl,"#******");
                   10391:       printf("#******");
                   10392:       fprintf(ficlog,"#******");
                   10393:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10394:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10395:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10396:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10397:       }
                   10398:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10399:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10400:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10401:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10402:       }
                   10403:       fprintf(ficrespl,"******\n");
                   10404:       printf("******\n");
                   10405:       fprintf(ficlog,"******\n");
                   10406:       if(invalidvarcomb[k]){
                   10407:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10408:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10409:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10410:        continue;
                   10411:       }
1.219     brouard  10412: 
1.238     brouard  10413:       fprintf(ficrespl,"#Age ");
                   10414:       for(j=1;j<=cptcoveff;j++) {
                   10415:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10416:       }
                   10417:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10418:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10419:     
1.238     brouard  10420:       for (age=agebase; age<=agelim; age++){
                   10421:        /* for (age=agebase; age<=agebase; age++){ */
                   10422:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10423:        fprintf(ficrespl,"%.0f ",age );
                   10424:        for(j=1;j<=cptcoveff;j++)
                   10425:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10426:        tot=0.;
                   10427:        for(i=1; i<=nlstate;i++){
                   10428:          tot +=  prlim[i][i];
                   10429:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10430:        }
                   10431:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10432:       } /* Age */
                   10433:       /* was end of cptcod */
                   10434:     } /* cptcov */
                   10435:   } /* nres */
1.219     brouard  10436:   return 0;
1.180     brouard  10437: }
                   10438: 
1.218     brouard  10439: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10440:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10441:        
                   10442:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10443:    * at any age between ageminpar and agemaxpar
                   10444:         */
1.235     brouard  10445:   int i, j, k, i1, nres=0 ;
1.217     brouard  10446:   /* double ftolpl = 1.e-10; */
                   10447:   double age, agebase, agelim;
                   10448:   double tot;
1.218     brouard  10449:   /* double ***mobaverage; */
                   10450:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10451: 
                   10452:   strcpy(fileresplb,"PLB_");
                   10453:   strcat(fileresplb,fileresu);
                   10454:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10455:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10456:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10457:   }
1.288     brouard  10458:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10459:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10460:   pstamp(ficresplb);
1.288     brouard  10461:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10462:   fprintf(ficresplb,"#Age ");
                   10463:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10464:   fprintf(ficresplb,"\n");
                   10465:   
1.218     brouard  10466:   
                   10467:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10468:   
                   10469:   agebase=ageminpar;
                   10470:   agelim=agemaxpar;
                   10471:   
                   10472:   
1.227     brouard  10473:   i1=pow(2,cptcoveff);
1.218     brouard  10474:   if (cptcovn < 1){i1=1;}
1.227     brouard  10475:   
1.238     brouard  10476:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10477:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10478:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10479:        continue;
                   10480:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10481:       fprintf(ficresplb,"#******");
                   10482:       printf("#******");
                   10483:       fprintf(ficlog,"#******");
                   10484:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10485:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10486:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10487:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10488:       }
                   10489:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10490:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10491:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10492:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10493:       }
                   10494:       fprintf(ficresplb,"******\n");
                   10495:       printf("******\n");
                   10496:       fprintf(ficlog,"******\n");
                   10497:       if(invalidvarcomb[k]){
                   10498:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10499:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10500:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10501:        continue;
                   10502:       }
1.218     brouard  10503:     
1.238     brouard  10504:       fprintf(ficresplb,"#Age ");
                   10505:       for(j=1;j<=cptcoveff;j++) {
                   10506:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10507:       }
                   10508:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10509:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10510:     
                   10511:     
1.238     brouard  10512:       for (age=agebase; age<=agelim; age++){
                   10513:        /* for (age=agebase; age<=agebase; age++){ */
                   10514:        if(mobilavproj > 0){
                   10515:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10516:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10517:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10518:        }else if (mobilavproj == 0){
                   10519:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10520:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10521:          exit(1);
                   10522:        }else{
                   10523:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10524:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10525:          /* printf("TOTOT\n"); */
                   10526:           /* exit(1); */
1.238     brouard  10527:        }
                   10528:        fprintf(ficresplb,"%.0f ",age );
                   10529:        for(j=1;j<=cptcoveff;j++)
                   10530:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10531:        tot=0.;
                   10532:        for(i=1; i<=nlstate;i++){
                   10533:          tot +=  bprlim[i][i];
                   10534:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10535:        }
                   10536:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10537:       } /* Age */
                   10538:       /* was end of cptcod */
1.255     brouard  10539:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10540:     } /* end of any combination */
                   10541:   } /* end of nres */  
1.218     brouard  10542:   /* hBijx(p, bage, fage); */
                   10543:   /* fclose(ficrespijb); */
                   10544:   
                   10545:   return 0;
1.217     brouard  10546: }
1.218     brouard  10547:  
1.180     brouard  10548: int hPijx(double *p, int bage, int fage){
                   10549:     /*------------- h Pij x at various ages ------------*/
                   10550: 
                   10551:   int stepsize;
                   10552:   int agelim;
                   10553:   int hstepm;
                   10554:   int nhstepm;
1.235     brouard  10555:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10556: 
                   10557:   double agedeb;
                   10558:   double ***p3mat;
                   10559: 
1.201     brouard  10560:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10561:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10562:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10563:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10564:     }
                   10565:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10566:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10567:   
                   10568:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10569:     /*if (stepm<=24) stepsize=2;*/
                   10570: 
                   10571:     agelim=AGESUP;
                   10572:     hstepm=stepsize*YEARM; /* Every year of age */
                   10573:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10574:                
1.180     brouard  10575:     /* hstepm=1;   aff par mois*/
                   10576:     pstamp(ficrespij);
                   10577:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10578:     i1= pow(2,cptcoveff);
1.218     brouard  10579:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10580:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10581:                /*      k=k+1;  */
1.235     brouard  10582:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10583:     for(k=1; k<=i1;k++){
1.253     brouard  10584:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10585:        continue;
1.183     brouard  10586:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10587:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10588:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10589:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10590:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10591:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10592:       }
1.183     brouard  10593:       fprintf(ficrespij,"******\n");
                   10594:       
                   10595:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10596:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10597:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10598:        
                   10599:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10600:        
1.183     brouard  10601:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10602:        oldm=oldms;savm=savms;
1.235     brouard  10603:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10604:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10605:        for(i=1; i<=nlstate;i++)
                   10606:          for(j=1; j<=nlstate+ndeath;j++)
                   10607:            fprintf(ficrespij," %1d-%1d",i,j);
                   10608:        fprintf(ficrespij,"\n");
                   10609:        for (h=0; h<=nhstepm; h++){
                   10610:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10611:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10612:          for(i=1; i<=nlstate;i++)
                   10613:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10614:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10615:          fprintf(ficrespij,"\n");
                   10616:        }
1.183     brouard  10617:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10618:        fprintf(ficrespij,"\n");
                   10619:       }
1.180     brouard  10620:       /*}*/
                   10621:     }
1.218     brouard  10622:     return 0;
1.180     brouard  10623: }
1.218     brouard  10624:  
                   10625:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10626:     /*------------- h Bij x at various ages ------------*/
                   10627: 
                   10628:   int stepsize;
1.218     brouard  10629:   /* int agelim; */
                   10630:        int ageminl;
1.217     brouard  10631:   int hstepm;
                   10632:   int nhstepm;
1.238     brouard  10633:   int h, i, i1, j, k, nres;
1.218     brouard  10634:        
1.217     brouard  10635:   double agedeb;
                   10636:   double ***p3mat;
1.218     brouard  10637:        
                   10638:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10639:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10640:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10641:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10642:   }
                   10643:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10644:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10645:   
                   10646:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10647:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10648:   
1.218     brouard  10649:   /* agelim=AGESUP; */
1.289   ! brouard  10650:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10651:   hstepm=stepsize*YEARM; /* Every year of age */
                   10652:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10653:   
                   10654:   /* hstepm=1;   aff par mois*/
                   10655:   pstamp(ficrespijb);
1.255     brouard  10656:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10657:   i1= pow(2,cptcoveff);
1.218     brouard  10658:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10659:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10660:   /*   k=k+1;  */
1.238     brouard  10661:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10662:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10663:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10664:        continue;
                   10665:       fprintf(ficrespijb,"\n#****** ");
                   10666:       for(j=1;j<=cptcoveff;j++)
                   10667:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10668:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10669:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10670:       }
                   10671:       fprintf(ficrespijb,"******\n");
1.264     brouard  10672:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10673:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10674:        continue;
                   10675:       }
                   10676:       
                   10677:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10678:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10679:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10680:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10681:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10682:        
                   10683:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10684:        
1.266     brouard  10685:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10686:        /* and memory limitations if stepm is small */
                   10687: 
1.238     brouard  10688:        /* oldm=oldms;savm=savms; */
                   10689:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10690:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10691:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10692:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10693:        for(i=1; i<=nlstate;i++)
                   10694:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10695:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10696:        fprintf(ficrespijb,"\n");
1.238     brouard  10697:        for (h=0; h<=nhstepm; h++){
                   10698:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10699:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10700:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10701:          for(i=1; i<=nlstate;i++)
                   10702:            for(j=1; j<=nlstate+ndeath;j++)
                   10703:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10704:          fprintf(ficrespijb,"\n");
                   10705:        }
                   10706:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10707:        fprintf(ficrespijb,"\n");
                   10708:       } /* end age deb */
                   10709:     } /* end combination */
                   10710:   } /* end nres */
1.218     brouard  10711:   return 0;
                   10712:  } /*  hBijx */
1.217     brouard  10713: 
1.180     brouard  10714: 
1.136     brouard  10715: /***********************************************/
                   10716: /**************** Main Program *****************/
                   10717: /***********************************************/
                   10718: 
                   10719: int main(int argc, char *argv[])
                   10720: {
                   10721: #ifdef GSL
                   10722:   const gsl_multimin_fminimizer_type *T;
                   10723:   size_t iteri = 0, it;
                   10724:   int rval = GSL_CONTINUE;
                   10725:   int status = GSL_SUCCESS;
                   10726:   double ssval;
                   10727: #endif
                   10728:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.164     brouard  10729:   int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
1.209     brouard  10730:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10731:   int jj, ll, li, lj, lk;
1.136     brouard  10732:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10733:   int num_filled;
1.136     brouard  10734:   int itimes;
                   10735:   int NDIM=2;
                   10736:   int vpopbased=0;
1.235     brouard  10737:   int nres=0;
1.258     brouard  10738:   int endishere=0;
1.277     brouard  10739:   int noffset=0;
1.274     brouard  10740:   int ncurrv=0; /* Temporary variable */
                   10741:   
1.164     brouard  10742:   char ca[32], cb[32];
1.136     brouard  10743:   /*  FILE *fichtm; *//* Html File */
                   10744:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10745:   struct stat info;
1.191     brouard  10746:   double agedeb=0.;
1.194     brouard  10747: 
                   10748:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10749:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10750: 
1.165     brouard  10751:   double fret;
1.191     brouard  10752:   double dum=0.; /* Dummy variable */
1.136     brouard  10753:   double ***p3mat;
1.218     brouard  10754:   /* double ***mobaverage; */
1.164     brouard  10755: 
                   10756:   char line[MAXLINE];
1.197     brouard  10757:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10758: 
1.234     brouard  10759:   char  modeltemp[MAXLINE];
1.230     brouard  10760:   char resultline[MAXLINE];
                   10761:   
1.136     brouard  10762:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10763:   char *tok, *val; /* pathtot */
1.136     brouard  10764:   int firstobs=1, lastobs=10;
1.195     brouard  10765:   int c,  h , cpt, c2;
1.191     brouard  10766:   int jl=0;
                   10767:   int i1, j1, jk, stepsize=0;
1.194     brouard  10768:   int count=0;
                   10769: 
1.164     brouard  10770:   int *tab; 
1.136     brouard  10771:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10772:   int backcast=0;
1.136     brouard  10773:   int mobilav=0,popforecast=0;
1.191     brouard  10774:   int hstepm=0, nhstepm=0;
1.136     brouard  10775:   int agemortsup;
                   10776:   float  sumlpop=0.;
                   10777:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10778:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10779: 
1.191     brouard  10780:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10781:   double ftolpl=FTOL;
                   10782:   double **prlim;
1.217     brouard  10783:   double **bprlim;
1.136     brouard  10784:   double ***param; /* Matrix of parameters */
1.251     brouard  10785:   double ***paramstart; /* Matrix of starting parameter values */
                   10786:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10787:   double **matcov; /* Matrix of covariance */
1.203     brouard  10788:   double **hess; /* Hessian matrix */
1.136     brouard  10789:   double ***delti3; /* Scale */
                   10790:   double *delti; /* Scale */
                   10791:   double ***eij, ***vareij;
                   10792:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10793: 
1.136     brouard  10794:   double *epj, vepp;
1.164     brouard  10795: 
1.273     brouard  10796:   double dateprev1, dateprev2;
                   10797:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10798:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10799: 
1.136     brouard  10800:   double **ximort;
1.145     brouard  10801:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10802:   int *dcwave;
                   10803: 
1.164     brouard  10804:   char z[1]="c";
1.136     brouard  10805: 
                   10806:   /*char  *strt;*/
                   10807:   char strtend[80];
1.126     brouard  10808: 
1.164     brouard  10809: 
1.126     brouard  10810: /*   setlocale (LC_ALL, ""); */
                   10811: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10812: /*   textdomain (PACKAGE); */
                   10813: /*   setlocale (LC_CTYPE, ""); */
                   10814: /*   setlocale (LC_MESSAGES, ""); */
                   10815: 
                   10816:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10817:   rstart_time = time(NULL);  
                   10818:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10819:   start_time = *localtime(&rstart_time);
1.126     brouard  10820:   curr_time=start_time;
1.157     brouard  10821:   /*tml = *localtime(&start_time.tm_sec);*/
                   10822:   /* strcpy(strstart,asctime(&tml)); */
                   10823:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10824: 
                   10825: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10826: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10827: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10828: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10829: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10830: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10831: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10832: /*   strt=asctime(&tmg); */
                   10833: /*   printf("Time(after) =%s",strstart);  */
                   10834: /*  (void) time (&time_value);
                   10835: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10836: *  tm = *localtime(&time_value);
                   10837: *  strstart=asctime(&tm);
                   10838: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10839: */
                   10840: 
                   10841:   nberr=0; /* Number of errors and warnings */
                   10842:   nbwarn=0;
1.184     brouard  10843: #ifdef WIN32
                   10844:   _getcwd(pathcd, size);
                   10845: #else
1.126     brouard  10846:   getcwd(pathcd, size);
1.184     brouard  10847: #endif
1.191     brouard  10848:   syscompilerinfo(0);
1.196     brouard  10849:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10850:   if(argc <=1){
                   10851:     printf("\nEnter the parameter file name: ");
1.205     brouard  10852:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10853:       printf("ERROR Empty parameter file name\n");
                   10854:       goto end;
                   10855:     }
1.126     brouard  10856:     i=strlen(pathr);
                   10857:     if(pathr[i-1]=='\n')
                   10858:       pathr[i-1]='\0';
1.156     brouard  10859:     i=strlen(pathr);
1.205     brouard  10860:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10861:       pathr[i-1]='\0';
1.205     brouard  10862:     }
                   10863:     i=strlen(pathr);
                   10864:     if( i==0 ){
                   10865:       printf("ERROR Empty parameter file name\n");
                   10866:       goto end;
                   10867:     }
                   10868:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10869:       printf("Pathr |%s|\n",pathr);
                   10870:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10871:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10872:       strcpy (pathtot, val);
                   10873:       if(pathr[0] == '\0') break; /* Dirty */
                   10874:     }
                   10875:   }
1.281     brouard  10876:   else if (argc<=2){
                   10877:     strcpy(pathtot,argv[1]);
                   10878:   }
1.126     brouard  10879:   else{
                   10880:     strcpy(pathtot,argv[1]);
1.281     brouard  10881:     strcpy(z,argv[2]);
                   10882:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10883:   }
                   10884:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10885:   /*cygwin_split_path(pathtot,path,optionfile);
                   10886:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10887:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10888: 
                   10889:   /* Split argv[0], imach program to get pathimach */
                   10890:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10891:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10892:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10893:  /*   strcpy(pathimach,argv[0]); */
                   10894:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10895:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10896:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10897: #ifdef WIN32
                   10898:   _chdir(path); /* Can be a relative path */
                   10899:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10900: #else
1.126     brouard  10901:   chdir(path); /* Can be a relative path */
1.184     brouard  10902:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10903: #endif
                   10904:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10905:   strcpy(command,"mkdir ");
                   10906:   strcat(command,optionfilefiname);
                   10907:   if((outcmd=system(command)) != 0){
1.169     brouard  10908:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10909:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10910:     /* fclose(ficlog); */
                   10911: /*     exit(1); */
                   10912:   }
                   10913: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10914: /*     perror("mkdir"); */
                   10915: /*   } */
                   10916: 
                   10917:   /*-------- arguments in the command line --------*/
                   10918: 
1.186     brouard  10919:   /* Main Log file */
1.126     brouard  10920:   strcat(filelog, optionfilefiname);
                   10921:   strcat(filelog,".log");    /* */
                   10922:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10923:     printf("Problem with logfile %s\n",filelog);
                   10924:     goto end;
                   10925:   }
                   10926:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10927:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10928:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10929:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10930:  path=%s \n\
                   10931:  optionfile=%s\n\
                   10932:  optionfilext=%s\n\
1.156     brouard  10933:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10934: 
1.197     brouard  10935:   syscompilerinfo(1);
1.167     brouard  10936: 
1.126     brouard  10937:   printf("Local time (at start):%s",strstart);
                   10938:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10939:   fflush(ficlog);
                   10940: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10941: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10942: 
                   10943:   /* */
                   10944:   strcpy(fileres,"r");
                   10945:   strcat(fileres, optionfilefiname);
1.201     brouard  10946:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10947:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10948:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10949: 
1.186     brouard  10950:   /* Main ---------arguments file --------*/
1.126     brouard  10951: 
                   10952:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10953:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10954:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10955:     fflush(ficlog);
1.149     brouard  10956:     /* goto end; */
                   10957:     exit(70); 
1.126     brouard  10958:   }
                   10959: 
                   10960:   strcpy(filereso,"o");
1.201     brouard  10961:   strcat(filereso,fileresu);
1.126     brouard  10962:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10963:     printf("Problem with Output resultfile: %s\n", filereso);
                   10964:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10965:     fflush(ficlog);
                   10966:     goto end;
                   10967:   }
1.278     brouard  10968:       /*-------- Rewriting parameter file ----------*/
                   10969:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10970:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10971:   strcat(rfileres,".");    /* */
                   10972:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10973:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10974:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10975:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   10976:     fflush(ficlog);
                   10977:     goto end;
                   10978:   }
                   10979:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  10980: 
1.278     brouard  10981:                                      
1.126     brouard  10982:   /* Reads comments: lines beginning with '#' */
                   10983:   numlinepar=0;
1.277     brouard  10984:   /* Is it a BOM UTF-8 Windows file? */
                   10985:   /* First parameter line */
1.197     brouard  10986:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  10987:     noffset=0;
                   10988:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   10989:     {
                   10990:       noffset=noffset+3;
                   10991:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   10992:     }
                   10993:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   10994:     {
                   10995:       noffset=noffset+2;
                   10996:       printf("# File is an UTF16BE BOM file\n");
                   10997:     }
                   10998:     else if( line[0] == 0 && line[1] == 0)
                   10999:     {
                   11000:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11001:        noffset=noffset+4;
                   11002:        printf("# File is an UTF16BE BOM file\n");
                   11003:       }
                   11004:     } else{
                   11005:       ;/*printf(" Not a BOM file\n");*/
                   11006:     }
                   11007:   
1.197     brouard  11008:     /* If line starts with a # it is a comment */
1.277     brouard  11009:     if (line[noffset] == '#') {
1.197     brouard  11010:       numlinepar++;
                   11011:       fputs(line,stdout);
                   11012:       fputs(line,ficparo);
1.278     brouard  11013:       fputs(line,ficres);
1.197     brouard  11014:       fputs(line,ficlog);
                   11015:       continue;
                   11016:     }else
                   11017:       break;
                   11018:   }
                   11019:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11020:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11021:     if (num_filled != 5) {
                   11022:       printf("Should be 5 parameters\n");
1.283     brouard  11023:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11024:     }
1.126     brouard  11025:     numlinepar++;
1.197     brouard  11026:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11027:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11028:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11029:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11030:   }
                   11031:   /* Second parameter line */
                   11032:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11033:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11034:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11035:     if (line[0] == '#') {
                   11036:       numlinepar++;
1.283     brouard  11037:       printf("%s",line);
                   11038:       fprintf(ficres,"%s",line);
                   11039:       fprintf(ficparo,"%s",line);
                   11040:       fprintf(ficlog,"%s",line);
1.197     brouard  11041:       continue;
                   11042:     }else
                   11043:       break;
                   11044:   }
1.223     brouard  11045:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11046:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11047:     if (num_filled != 11) {
                   11048:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11049:       printf("but line=%s\n",line);
1.283     brouard  11050:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11051:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11052:     }
1.286     brouard  11053:     if( lastpass > maxwav){
                   11054:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11055:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11056:       fflush(ficlog);
                   11057:       goto end;
                   11058:     }
                   11059:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11060:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11061:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11062:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11063:   }
1.203     brouard  11064:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11065:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11066:   /* Third parameter line */
                   11067:   while(fgets(line, MAXLINE, ficpar)) {
                   11068:     /* If line starts with a # it is a comment */
                   11069:     if (line[0] == '#') {
                   11070:       numlinepar++;
1.283     brouard  11071:       printf("%s",line);
                   11072:       fprintf(ficres,"%s",line);
                   11073:       fprintf(ficparo,"%s",line);
                   11074:       fprintf(ficlog,"%s",line);
1.197     brouard  11075:       continue;
                   11076:     }else
                   11077:       break;
                   11078:   }
1.201     brouard  11079:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11080:     if (num_filled != 1){
                   11081:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11082:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11083:       model[0]='\0';
                   11084:       goto end;
                   11085:     }
                   11086:     else{
                   11087:       if (model[0]=='+'){
                   11088:        for(i=1; i<=strlen(model);i++)
                   11089:          modeltemp[i-1]=model[i];
1.201     brouard  11090:        strcpy(model,modeltemp); 
1.197     brouard  11091:       }
                   11092:     }
1.199     brouard  11093:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11094:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11095:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11096:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11097:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11098:   }
                   11099:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11100:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11101:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11102:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11103:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11104:   fflush(ficlog);
1.190     brouard  11105:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11106:   if(model[0]=='#'){
1.279     brouard  11107:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11108:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11109:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11110:     if(mle != -1){
1.279     brouard  11111:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11112:       exit(1);
                   11113:     }
                   11114:   }
1.126     brouard  11115:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11116:     ungetc(c,ficpar);
                   11117:     fgets(line, MAXLINE, ficpar);
                   11118:     numlinepar++;
1.195     brouard  11119:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11120:       z[0]=line[1];
                   11121:     }
                   11122:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11123:     fputs(line, stdout);
                   11124:     //puts(line);
1.126     brouard  11125:     fputs(line,ficparo);
                   11126:     fputs(line,ficlog);
                   11127:   }
                   11128:   ungetc(c,ficpar);
                   11129: 
                   11130:    
1.145     brouard  11131:   covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
1.268     brouard  11132:   if(nqv>=1)coqvar=matrix(1,nqv,1,n);  /**< Fixed quantitative covariate */
                   11133:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,1,n);  /**< Time varying quantitative covariate */
                   11134:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,1,n);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11135:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11136:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11137:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11138:   */
                   11139:   if (strlen(model)>1) 
1.187     brouard  11140:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11141:   else
1.187     brouard  11142:     ncovmodel=2; /* Constant and age */
1.133     brouard  11143:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11144:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11145:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11146:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11147:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11148:     fflush(stdout);
                   11149:     fclose (ficlog);
                   11150:     goto end;
                   11151:   }
1.126     brouard  11152:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11153:   delti=delti3[1][1];
                   11154:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11155:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11156: /* We could also provide initial parameters values giving by simple logistic regression 
                   11157:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11158:       /* for(i=1;i<nlstate;i++){ */
                   11159:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11160:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11161:       /* } */
1.126     brouard  11162:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11163:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11164:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11165:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11166:     fclose (ficparo);
                   11167:     fclose (ficlog);
                   11168:     goto end;
                   11169:     exit(0);
1.220     brouard  11170:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11171:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11172:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11173:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11174:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11175:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11176:     hess=matrix(1,npar,1,npar);
1.220     brouard  11177:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11178:     /* Read guessed parameters */
1.126     brouard  11179:     /* Reads comments: lines beginning with '#' */
                   11180:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11181:       ungetc(c,ficpar);
                   11182:       fgets(line, MAXLINE, ficpar);
                   11183:       numlinepar++;
1.141     brouard  11184:       fputs(line,stdout);
1.126     brouard  11185:       fputs(line,ficparo);
                   11186:       fputs(line,ficlog);
                   11187:     }
                   11188:     ungetc(c,ficpar);
                   11189:     
                   11190:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11191:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11192:     for(i=1; i <=nlstate; i++){
1.234     brouard  11193:       j=0;
1.126     brouard  11194:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11195:        if(jj==i) continue;
                   11196:        j++;
                   11197:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11198:        if ((i1 != i) || (j1 != jj)){
                   11199:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11200: It might be a problem of design; if ncovcol and the model are correct\n \
                   11201: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11202:          exit(1);
                   11203:        }
                   11204:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11205:        if(mle==1)
                   11206:          printf("%1d%1d",i,jj);
                   11207:        fprintf(ficlog,"%1d%1d",i,jj);
                   11208:        for(k=1; k<=ncovmodel;k++){
                   11209:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11210:          if(mle==1){
                   11211:            printf(" %lf",param[i][j][k]);
                   11212:            fprintf(ficlog," %lf",param[i][j][k]);
                   11213:          }
                   11214:          else
                   11215:            fprintf(ficlog," %lf",param[i][j][k]);
                   11216:          fprintf(ficparo," %lf",param[i][j][k]);
                   11217:        }
                   11218:        fscanf(ficpar,"\n");
                   11219:        numlinepar++;
                   11220:        if(mle==1)
                   11221:          printf("\n");
                   11222:        fprintf(ficlog,"\n");
                   11223:        fprintf(ficparo,"\n");
1.126     brouard  11224:       }
                   11225:     }  
                   11226:     fflush(ficlog);
1.234     brouard  11227:     
1.251     brouard  11228:     /* Reads parameters values */
1.126     brouard  11229:     p=param[1][1];
1.251     brouard  11230:     pstart=paramstart[1][1];
1.126     brouard  11231:     
                   11232:     /* Reads comments: lines beginning with '#' */
                   11233:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11234:       ungetc(c,ficpar);
                   11235:       fgets(line, MAXLINE, ficpar);
                   11236:       numlinepar++;
1.141     brouard  11237:       fputs(line,stdout);
1.126     brouard  11238:       fputs(line,ficparo);
                   11239:       fputs(line,ficlog);
                   11240:     }
                   11241:     ungetc(c,ficpar);
                   11242: 
                   11243:     for(i=1; i <=nlstate; i++){
                   11244:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11245:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11246:        if ( (i1-i) * (j1-j) != 0){
                   11247:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11248:          exit(1);
                   11249:        }
                   11250:        printf("%1d%1d",i,j);
                   11251:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11252:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11253:        for(k=1; k<=ncovmodel;k++){
                   11254:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11255:          printf(" %le",delti3[i][j][k]);
                   11256:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11257:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11258:        }
                   11259:        fscanf(ficpar,"\n");
                   11260:        numlinepar++;
                   11261:        printf("\n");
                   11262:        fprintf(ficparo,"\n");
                   11263:        fprintf(ficlog,"\n");
1.126     brouard  11264:       }
                   11265:     }
                   11266:     fflush(ficlog);
1.234     brouard  11267:     
1.145     brouard  11268:     /* Reads covariance matrix */
1.126     brouard  11269:     delti=delti3[1][1];
1.220     brouard  11270:                
                   11271:                
1.126     brouard  11272:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11273:                
1.126     brouard  11274:     /* Reads comments: lines beginning with '#' */
                   11275:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11276:       ungetc(c,ficpar);
                   11277:       fgets(line, MAXLINE, ficpar);
                   11278:       numlinepar++;
1.141     brouard  11279:       fputs(line,stdout);
1.126     brouard  11280:       fputs(line,ficparo);
                   11281:       fputs(line,ficlog);
                   11282:     }
                   11283:     ungetc(c,ficpar);
1.220     brouard  11284:                
1.126     brouard  11285:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11286:     hess=matrix(1,npar,1,npar);
1.131     brouard  11287:     for(i=1; i <=npar; i++)
                   11288:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11289:                
1.194     brouard  11290:     /* Scans npar lines */
1.126     brouard  11291:     for(i=1; i <=npar; i++){
1.226     brouard  11292:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11293:       if(count != 3){
1.226     brouard  11294:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11295: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11296: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11297:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11298: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11299: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11300:        exit(1);
1.220     brouard  11301:       }else{
1.226     brouard  11302:        if(mle==1)
                   11303:          printf("%1d%1d%d",i1,j1,jk);
                   11304:       }
                   11305:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11306:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11307:       for(j=1; j <=i; j++){
1.226     brouard  11308:        fscanf(ficpar," %le",&matcov[i][j]);
                   11309:        if(mle==1){
                   11310:          printf(" %.5le",matcov[i][j]);
                   11311:        }
                   11312:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11313:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11314:       }
                   11315:       fscanf(ficpar,"\n");
                   11316:       numlinepar++;
                   11317:       if(mle==1)
1.220     brouard  11318:                                printf("\n");
1.126     brouard  11319:       fprintf(ficlog,"\n");
                   11320:       fprintf(ficparo,"\n");
                   11321:     }
1.194     brouard  11322:     /* End of read covariance matrix npar lines */
1.126     brouard  11323:     for(i=1; i <=npar; i++)
                   11324:       for(j=i+1;j<=npar;j++)
1.226     brouard  11325:        matcov[i][j]=matcov[j][i];
1.126     brouard  11326:     
                   11327:     if(mle==1)
                   11328:       printf("\n");
                   11329:     fprintf(ficlog,"\n");
                   11330:     
                   11331:     fflush(ficlog);
                   11332:     
                   11333:   }    /* End of mle != -3 */
1.218     brouard  11334:   
1.186     brouard  11335:   /*  Main data
                   11336:    */
1.126     brouard  11337:   n= lastobs;
                   11338:   num=lvector(1,n);
                   11339:   moisnais=vector(1,n);
                   11340:   annais=vector(1,n);
                   11341:   moisdc=vector(1,n);
                   11342:   andc=vector(1,n);
1.220     brouard  11343:   weight=vector(1,n);
1.126     brouard  11344:   agedc=vector(1,n);
                   11345:   cod=ivector(1,n);
1.220     brouard  11346:   for(i=1;i<=n;i++){
1.234     brouard  11347:     num[i]=0;
                   11348:     moisnais[i]=0;
                   11349:     annais[i]=0;
                   11350:     moisdc[i]=0;
                   11351:     andc[i]=0;
                   11352:     agedc[i]=0;
                   11353:     cod[i]=0;
                   11354:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11355:   }
1.126     brouard  11356:   mint=matrix(1,maxwav,1,n);
                   11357:   anint=matrix(1,maxwav,1,n);
1.131     brouard  11358:   s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11359:   tab=ivector(1,NCOVMAX);
1.144     brouard  11360:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11361:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11362: 
1.136     brouard  11363:   /* Reads data from file datafile */
                   11364:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11365:     goto end;
                   11366: 
                   11367:   /* Calculation of the number of parameters from char model */
1.234     brouard  11368:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11369:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11370:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11371:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11372:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11373:   */
                   11374:   
                   11375:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11376:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11377:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11378:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11379:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11380:   TvarF=ivector(1,NCOVMAX); /*  */
                   11381:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11382:   TvarV=ivector(1,NCOVMAX); /*  */
                   11383:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11384:   TvarA=ivector(1,NCOVMAX); /*  */
                   11385:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11386:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11387:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11388:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11389:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11390:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11391:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11392:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11393:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11394: 
1.230     brouard  11395:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11396:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11397:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11398:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11399:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11400:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11401:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11402:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11403:   */
                   11404:   /* For model-covariate k tells which data-covariate to use but
                   11405:     because this model-covariate is a construction we invent a new column
                   11406:     ncovcol + k1
                   11407:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11408:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11409:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11410:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11411:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11412:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11413:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11414:   */
1.145     brouard  11415:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11416:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11417:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11418:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11419:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11420:                         4 covariates (3 plus signs)
                   11421:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11422:                      */  
1.230     brouard  11423:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11424:                                * individual dummy, fixed or varying:
                   11425:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11426:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11427:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11428:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11429:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11430:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11431:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11432:                                * individual quantitative, fixed or varying:
                   11433:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11434:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11435:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11436: /* Main decodemodel */
                   11437: 
1.187     brouard  11438: 
1.223     brouard  11439:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11440:     goto end;
                   11441: 
1.137     brouard  11442:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11443:     nbwarn++;
                   11444:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11445:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11446:   }
1.136     brouard  11447:     /*  if(mle==1){*/
1.137     brouard  11448:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11449:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11450:   }
                   11451: 
                   11452:     /*-calculation of age at interview from date of interview and age at death -*/
                   11453:   agev=matrix(1,maxwav,1,imx);
                   11454: 
                   11455:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11456:     goto end;
                   11457: 
1.126     brouard  11458: 
1.136     brouard  11459:   agegomp=(int)agemin;
                   11460:   free_vector(moisnais,1,n);
                   11461:   free_vector(annais,1,n);
1.126     brouard  11462:   /* free_matrix(mint,1,maxwav,1,n);
                   11463:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11464:   /* free_vector(moisdc,1,n); */
                   11465:   /* free_vector(andc,1,n); */
1.145     brouard  11466:   /* */
                   11467:   
1.126     brouard  11468:   wav=ivector(1,imx);
1.214     brouard  11469:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11470:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11471:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11472:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11473:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11474:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11475:    
                   11476:   /* Concatenates waves */
1.214     brouard  11477:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11478:      Death is a valid wave (if date is known).
                   11479:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11480:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11481:      and mw[mi+1][i]. dh depends on stepm.
                   11482:   */
                   11483: 
1.126     brouard  11484:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11485:   /* Concatenates waves */
1.145     brouard  11486:  
1.215     brouard  11487:   free_vector(moisdc,1,n);
                   11488:   free_vector(andc,1,n);
                   11489: 
1.126     brouard  11490:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11491:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11492:   ncodemax[1]=1;
1.145     brouard  11493:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11494:   cptcoveff=0;
1.220     brouard  11495:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11496:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11497:   }
                   11498:   
                   11499:   ncovcombmax=pow(2,cptcoveff);
                   11500:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11501:   for(i=1;i<ncovcombmax;i++)
                   11502:     invalidvarcomb[i]=0;
                   11503:   
1.211     brouard  11504:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11505:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11506:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11507:   
1.200     brouard  11508:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11509:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11510:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11511:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11512:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11513:    * (currently 0 or 1) in the data.
                   11514:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11515:    * corresponding modality (h,j).
                   11516:    */
                   11517: 
1.145     brouard  11518:   h=0;
                   11519:   /*if (cptcovn > 0) */
1.126     brouard  11520:   m=pow(2,cptcoveff);
                   11521:  
1.144     brouard  11522:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11523:           * For k=4 covariates, h goes from 1 to m=2**k
                   11524:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11525:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11526:           *     h\k   1     2     3     4
1.143     brouard  11527:           *______________________________  
                   11528:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11529:           *     2     2     1     1     1
                   11530:           *     3 i=2 1     2     1     1
                   11531:           *     4     2     2     1     1
                   11532:           *     5 i=3 1 i=2 1     2     1
                   11533:           *     6     2     1     2     1
                   11534:           *     7 i=4 1     2     2     1
                   11535:           *     8     2     2     2     1
1.197     brouard  11536:           *     9 i=5 1 i=3 1 i=2 1     2
                   11537:           *    10     2     1     1     2
                   11538:           *    11 i=6 1     2     1     2
                   11539:           *    12     2     2     1     2
                   11540:           *    13 i=7 1 i=4 1     2     2    
                   11541:           *    14     2     1     2     2
                   11542:           *    15 i=8 1     2     2     2
                   11543:           *    16     2     2     2     2
1.143     brouard  11544:           */
1.212     brouard  11545:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11546:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11547:      * and the value of each covariate?
                   11548:      * V1=1, V2=1, V3=2, V4=1 ?
                   11549:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11550:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11551:      * In order to get the real value in the data, we use nbcode
                   11552:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11553:      * We are keeping this crazy system in order to be able (in the future?) 
                   11554:      * to have more than 2 values (0 or 1) for a covariate.
                   11555:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11556:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11557:      *              bbbbbbbb
                   11558:      *              76543210     
                   11559:      *   h-1        00000101 (6-1=5)
1.219     brouard  11560:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11561:      *           &
                   11562:      *     1        00000001 (1)
1.219     brouard  11563:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11564:      *          +1= 00000001 =1 
1.211     brouard  11565:      *
                   11566:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11567:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11568:      *    >>k'            11
                   11569:      *          &   00000001
                   11570:      *            = 00000001
                   11571:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11572:      * Reverse h=6 and m=16?
                   11573:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11574:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11575:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11576:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11577:      * V3=decodtabm(14,3,2**4)=2
                   11578:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11579:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11580:      *          &1 000000001
                   11581:      *           = 000000001
                   11582:      *         +1= 000000010 =2
                   11583:      *                  2211
                   11584:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11585:      *                  V3=2
1.220     brouard  11586:                 * codtabm and decodtabm are identical
1.211     brouard  11587:      */
                   11588: 
1.145     brouard  11589: 
                   11590:  free_ivector(Ndum,-1,NCOVMAX);
                   11591: 
                   11592: 
1.126     brouard  11593:     
1.186     brouard  11594:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11595:   strcpy(optionfilegnuplot,optionfilefiname);
                   11596:   if(mle==-3)
1.201     brouard  11597:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11598:   strcat(optionfilegnuplot,".gp");
                   11599: 
                   11600:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11601:     printf("Problem with file %s",optionfilegnuplot);
                   11602:   }
                   11603:   else{
1.204     brouard  11604:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11605:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11606:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11607:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11608:   }
                   11609:   /*  fclose(ficgp);*/
1.186     brouard  11610: 
                   11611: 
                   11612:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11613: 
                   11614:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11615:   if(mle==-3)
1.201     brouard  11616:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11617:   strcat(optionfilehtm,".htm");
                   11618:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11619:     printf("Problem with %s \n",optionfilehtm);
                   11620:     exit(0);
1.126     brouard  11621:   }
                   11622: 
                   11623:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11624:   strcat(optionfilehtmcov,"-cov.htm");
                   11625:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11626:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11627:   }
                   11628:   else{
                   11629:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11630: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11631: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11632:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11633:   }
                   11634: 
1.213     brouard  11635:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11636: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11637: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11638: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11639: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11640: \n\
                   11641: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11642:  <ul><li><h4>Parameter files</h4>\n\
                   11643:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11644:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11645:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11646:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11647:  - Date and time at start: %s</ul>\n",\
                   11648:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11649:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11650:          fileres,fileres,\
                   11651:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11652:   fflush(fichtm);
                   11653: 
                   11654:   strcpy(pathr,path);
                   11655:   strcat(pathr,optionfilefiname);
1.184     brouard  11656: #ifdef WIN32
                   11657:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11658: #else
1.126     brouard  11659:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11660: #endif
                   11661:          
1.126     brouard  11662:   
1.220     brouard  11663:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11664:                 and for any valid combination of covariates
1.126     brouard  11665:      and prints on file fileres'p'. */
1.251     brouard  11666:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11667:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11668: 
                   11669:   fprintf(fichtm,"\n");
1.286     brouard  11670:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11671:          ftol, stepm);
                   11672:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11673:   ncurrv=1;
                   11674:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11675:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11676:   ncurrv=i;
                   11677:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
                   11678:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) covariates: ntv=%d ", ntv);
                   11679:   ncurrv=i;
                   11680:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
                   11681:   fprintf(fichtm,"\n<li>Number of quantitative time varying covariates: nqtv=%d ", nqtv);
                   11682:   ncurrv=i;
                   11683:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11684:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11685:           nlstate, ndeath, maxwav, mle, weightopt);
                   11686: 
                   11687:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11688: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11689: 
                   11690:   
                   11691:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11692: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11693: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11694:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11695:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11696:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11697:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11698:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11699:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11700: 
1.126     brouard  11701:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11702:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11703:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11704: 
                   11705:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11706:   /* For mortality only */
1.126     brouard  11707:   if (mle==-3){
1.136     brouard  11708:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11709:     for(i=1;i<=NDIM;i++)
                   11710:       for(j=1;j<=NDIM;j++)
                   11711:        ximort[i][j]=0.;
1.186     brouard  11712:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.126     brouard  11713:     cens=ivector(1,n);
                   11714:     ageexmed=vector(1,n);
                   11715:     agecens=vector(1,n);
                   11716:     dcwave=ivector(1,n);
1.223     brouard  11717:                
1.126     brouard  11718:     for (i=1; i<=imx; i++){
                   11719:       dcwave[i]=-1;
                   11720:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11721:        if (s[m][i]>nlstate) {
                   11722:          dcwave[i]=m;
                   11723:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11724:          break;
                   11725:        }
1.126     brouard  11726:     }
1.226     brouard  11727:     
1.126     brouard  11728:     for (i=1; i<=imx; i++) {
                   11729:       if (wav[i]>0){
1.226     brouard  11730:        ageexmed[i]=agev[mw[1][i]][i];
                   11731:        j=wav[i];
                   11732:        agecens[i]=1.; 
                   11733:        
                   11734:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11735:          agecens[i]=agev[mw[j][i]][i];
                   11736:          cens[i]= 1;
                   11737:        }else if (ageexmed[i]< 1) 
                   11738:          cens[i]= -1;
                   11739:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11740:          cens[i]=0 ;
1.126     brouard  11741:       }
                   11742:       else cens[i]=-1;
                   11743:     }
                   11744:     
                   11745:     for (i=1;i<=NDIM;i++) {
                   11746:       for (j=1;j<=NDIM;j++)
1.226     brouard  11747:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11748:     }
                   11749:     
1.145     brouard  11750:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11751:     /*printf("%lf %lf", p[1], p[2]);*/
                   11752:     
                   11753:     
1.136     brouard  11754: #ifdef GSL
                   11755:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11756: #else
1.126     brouard  11757:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11758: #endif
1.201     brouard  11759:     strcpy(filerespow,"POW-MORT_"); 
                   11760:     strcat(filerespow,fileresu);
1.126     brouard  11761:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11762:       printf("Problem with resultfile: %s\n", filerespow);
                   11763:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11764:     }
1.136     brouard  11765: #ifdef GSL
                   11766:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11767: #else
1.126     brouard  11768:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11769: #endif
1.126     brouard  11770:     /*  for (i=1;i<=nlstate;i++)
                   11771:        for(j=1;j<=nlstate+ndeath;j++)
                   11772:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11773:     */
                   11774:     fprintf(ficrespow,"\n");
1.136     brouard  11775: #ifdef GSL
                   11776:     /* gsl starts here */ 
                   11777:     T = gsl_multimin_fminimizer_nmsimplex;
                   11778:     gsl_multimin_fminimizer *sfm = NULL;
                   11779:     gsl_vector *ss, *x;
                   11780:     gsl_multimin_function minex_func;
                   11781: 
                   11782:     /* Initial vertex size vector */
                   11783:     ss = gsl_vector_alloc (NDIM);
                   11784:     
                   11785:     if (ss == NULL){
                   11786:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11787:     }
                   11788:     /* Set all step sizes to 1 */
                   11789:     gsl_vector_set_all (ss, 0.001);
                   11790: 
                   11791:     /* Starting point */
1.126     brouard  11792:     
1.136     brouard  11793:     x = gsl_vector_alloc (NDIM);
                   11794:     
                   11795:     if (x == NULL){
                   11796:       gsl_vector_free(ss);
                   11797:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11798:     }
                   11799:   
                   11800:     /* Initialize method and iterate */
                   11801:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11802:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11803:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11804:     gsl_vector_set(x, 0, p[1]);
                   11805:     gsl_vector_set(x, 1, p[2]);
                   11806: 
                   11807:     minex_func.f = &gompertz_f;
                   11808:     minex_func.n = NDIM;
                   11809:     minex_func.params = (void *)&p; /* ??? */
                   11810:     
                   11811:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11812:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11813:     
                   11814:     printf("Iterations beginning .....\n\n");
                   11815:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11816: 
                   11817:     iteri=0;
                   11818:     while (rval == GSL_CONTINUE){
                   11819:       iteri++;
                   11820:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11821:       
                   11822:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11823:       fflush(0);
                   11824:       
                   11825:       if (status) 
                   11826:         break;
                   11827:       
                   11828:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11829:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11830:       
                   11831:       if (rval == GSL_SUCCESS)
                   11832:         printf ("converged to a local maximum at\n");
                   11833:       
                   11834:       printf("%5d ", iteri);
                   11835:       for (it = 0; it < NDIM; it++){
                   11836:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11837:       }
                   11838:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11839:     }
                   11840:     
                   11841:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11842:     
                   11843:     gsl_vector_free(x); /* initial values */
                   11844:     gsl_vector_free(ss); /* inital step size */
                   11845:     for (it=0; it<NDIM; it++){
                   11846:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11847:       fprintf(ficrespow," %.12lf", p[it]);
                   11848:     }
                   11849:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11850: #endif
                   11851: #ifdef POWELL
                   11852:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11853: #endif  
1.126     brouard  11854:     fclose(ficrespow);
                   11855:     
1.203     brouard  11856:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11857: 
                   11858:     for(i=1; i <=NDIM; i++)
                   11859:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11860:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11861:     
                   11862:     printf("\nCovariance matrix\n ");
1.203     brouard  11863:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11864:     for(i=1; i <=NDIM; i++) {
                   11865:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11866:                                printf("%f ",matcov[i][j]);
                   11867:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11868:       }
1.203     brouard  11869:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11870:     }
                   11871:     
                   11872:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11873:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11874:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11875:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11876:     }
1.126     brouard  11877:     lsurv=vector(1,AGESUP);
                   11878:     lpop=vector(1,AGESUP);
                   11879:     tpop=vector(1,AGESUP);
                   11880:     lsurv[agegomp]=100000;
                   11881:     
                   11882:     for (k=agegomp;k<=AGESUP;k++) {
                   11883:       agemortsup=k;
                   11884:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11885:     }
                   11886:     
                   11887:     for (k=agegomp;k<agemortsup;k++)
                   11888:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11889:     
                   11890:     for (k=agegomp;k<agemortsup;k++){
                   11891:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11892:       sumlpop=sumlpop+lpop[k];
                   11893:     }
                   11894:     
                   11895:     tpop[agegomp]=sumlpop;
                   11896:     for (k=agegomp;k<(agemortsup-3);k++){
                   11897:       /*  tpop[k+1]=2;*/
                   11898:       tpop[k+1]=tpop[k]-lpop[k];
                   11899:     }
                   11900:     
                   11901:     
                   11902:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11903:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11904:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11905:     
                   11906:     
                   11907:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11908:                ageminpar=50;
                   11909:                agemaxpar=100;
1.194     brouard  11910:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11911:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11912: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11913: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11914:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11915: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11916: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11917:     }else{
                   11918:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11919:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11920:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11921:                }
1.201     brouard  11922:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11923:                     stepm, weightopt,\
                   11924:                     model,imx,p,matcov,agemortsup);
                   11925:     
                   11926:     free_vector(lsurv,1,AGESUP);
                   11927:     free_vector(lpop,1,AGESUP);
                   11928:     free_vector(tpop,1,AGESUP);
1.220     brouard  11929:     free_matrix(ximort,1,NDIM,1,NDIM);
1.136     brouard  11930:     free_ivector(cens,1,n);
                   11931:     free_vector(agecens,1,n);
                   11932:     free_ivector(dcwave,1,n);
1.220     brouard  11933: #ifdef GSL
1.136     brouard  11934: #endif
1.186     brouard  11935:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11936:   /* Standard  */
                   11937:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11938:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11939:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11940:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11941:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11942:     for (k=1; k<=npar;k++)
                   11943:       printf(" %d %8.5f",k,p[k]);
                   11944:     printf("\n");
1.205     brouard  11945:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11946:       /* mlikeli uses func not funcone */
1.247     brouard  11947:       /* for(i=1;i<nlstate;i++){ */
                   11948:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11949:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11950:       /* } */
1.205     brouard  11951:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11952:     }
                   11953:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11954:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11955:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11956:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11957:     }
                   11958:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11959:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11960:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11961:     for (k=1; k<=npar;k++)
                   11962:       printf(" %d %8.5f",k,p[k]);
                   11963:     printf("\n");
                   11964:     
                   11965:     /*--------- results files --------------*/
1.283     brouard  11966:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  11967:     
                   11968:     
                   11969:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11970:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11971:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11972:     for(i=1,jk=1; i <=nlstate; i++){
                   11973:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11974:        if (k != i) {
                   11975:          printf("%d%d ",i,k);
                   11976:          fprintf(ficlog,"%d%d ",i,k);
                   11977:          fprintf(ficres,"%1d%1d ",i,k);
                   11978:          for(j=1; j <=ncovmodel; j++){
                   11979:            printf("%12.7f ",p[jk]);
                   11980:            fprintf(ficlog,"%12.7f ",p[jk]);
                   11981:            fprintf(ficres,"%12.7f ",p[jk]);
                   11982:            jk++; 
                   11983:          }
                   11984:          printf("\n");
                   11985:          fprintf(ficlog,"\n");
                   11986:          fprintf(ficres,"\n");
                   11987:        }
1.126     brouard  11988:       }
                   11989:     }
1.203     brouard  11990:     if(mle != 0){
                   11991:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  11992:       ftolhess=ftol; /* Usually correct */
1.203     brouard  11993:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   11994:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11995:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   11996:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  11997:        for(k=1; k <=(nlstate+ndeath); k++){
                   11998:          if (k != i) {
                   11999:            printf("%d%d ",i,k);
                   12000:            fprintf(ficlog,"%d%d ",i,k);
                   12001:            for(j=1; j <=ncovmodel; j++){
                   12002:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12003:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12004:              jk++; 
                   12005:            }
                   12006:            printf("\n");
                   12007:            fprintf(ficlog,"\n");
                   12008:          }
                   12009:        }
1.193     brouard  12010:       }
1.203     brouard  12011:     } /* end of hesscov and Wald tests */
1.225     brouard  12012:     
1.203     brouard  12013:     /*  */
1.126     brouard  12014:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12015:     printf("# Scales (for hessian or gradient estimation)\n");
                   12016:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12017:     for(i=1,jk=1; i <=nlstate; i++){
                   12018:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12019:        if (j!=i) {
                   12020:          fprintf(ficres,"%1d%1d",i,j);
                   12021:          printf("%1d%1d",i,j);
                   12022:          fprintf(ficlog,"%1d%1d",i,j);
                   12023:          for(k=1; k<=ncovmodel;k++){
                   12024:            printf(" %.5e",delti[jk]);
                   12025:            fprintf(ficlog," %.5e",delti[jk]);
                   12026:            fprintf(ficres," %.5e",delti[jk]);
                   12027:            jk++;
                   12028:          }
                   12029:          printf("\n");
                   12030:          fprintf(ficlog,"\n");
                   12031:          fprintf(ficres,"\n");
                   12032:        }
1.126     brouard  12033:       }
                   12034:     }
                   12035:     
                   12036:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12037:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12038:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12039:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12040:     /* # 121 Var(a12)\n\ */
                   12041:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12042:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12043:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12044:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12045:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12046:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12047:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12048:     
                   12049:     
                   12050:     /* Just to have a covariance matrix which will be more understandable
                   12051:        even is we still don't want to manage dictionary of variables
                   12052:     */
                   12053:     for(itimes=1;itimes<=2;itimes++){
                   12054:       jj=0;
                   12055:       for(i=1; i <=nlstate; i++){
1.225     brouard  12056:        for(j=1; j <=nlstate+ndeath; j++){
                   12057:          if(j==i) continue;
                   12058:          for(k=1; k<=ncovmodel;k++){
                   12059:            jj++;
                   12060:            ca[0]= k+'a'-1;ca[1]='\0';
                   12061:            if(itimes==1){
                   12062:              if(mle>=1)
                   12063:                printf("#%1d%1d%d",i,j,k);
                   12064:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12065:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12066:            }else{
                   12067:              if(mle>=1)
                   12068:                printf("%1d%1d%d",i,j,k);
                   12069:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12070:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12071:            }
                   12072:            ll=0;
                   12073:            for(li=1;li <=nlstate; li++){
                   12074:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12075:                if(lj==li) continue;
                   12076:                for(lk=1;lk<=ncovmodel;lk++){
                   12077:                  ll++;
                   12078:                  if(ll<=jj){
                   12079:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12080:                    if(ll<jj){
                   12081:                      if(itimes==1){
                   12082:                        if(mle>=1)
                   12083:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12084:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12085:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12086:                      }else{
                   12087:                        if(mle>=1)
                   12088:                          printf(" %.5e",matcov[jj][ll]); 
                   12089:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12090:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12091:                      }
                   12092:                    }else{
                   12093:                      if(itimes==1){
                   12094:                        if(mle>=1)
                   12095:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12096:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12097:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12098:                      }else{
                   12099:                        if(mle>=1)
                   12100:                          printf(" %.7e",matcov[jj][ll]); 
                   12101:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12102:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12103:                      }
                   12104:                    }
                   12105:                  }
                   12106:                } /* end lk */
                   12107:              } /* end lj */
                   12108:            } /* end li */
                   12109:            if(mle>=1)
                   12110:              printf("\n");
                   12111:            fprintf(ficlog,"\n");
                   12112:            fprintf(ficres,"\n");
                   12113:            numlinepar++;
                   12114:          } /* end k*/
                   12115:        } /*end j */
1.126     brouard  12116:       } /* end i */
                   12117:     } /* end itimes */
                   12118:     
                   12119:     fflush(ficlog);
                   12120:     fflush(ficres);
1.225     brouard  12121:     while(fgets(line, MAXLINE, ficpar)) {
                   12122:       /* If line starts with a # it is a comment */
                   12123:       if (line[0] == '#') {
                   12124:        numlinepar++;
                   12125:        fputs(line,stdout);
                   12126:        fputs(line,ficparo);
                   12127:        fputs(line,ficlog);
                   12128:        continue;
                   12129:       }else
                   12130:        break;
                   12131:     }
                   12132:     
1.209     brouard  12133:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12134:     /*   ungetc(c,ficpar); */
                   12135:     /*   fgets(line, MAXLINE, ficpar); */
                   12136:     /*   fputs(line,stdout); */
                   12137:     /*   fputs(line,ficparo); */
                   12138:     /* } */
                   12139:     /* ungetc(c,ficpar); */
1.126     brouard  12140:     
                   12141:     estepm=0;
1.209     brouard  12142:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12143:       
                   12144:       if (num_filled != 6) {
                   12145:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12146:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12147:        goto end;
                   12148:       }
                   12149:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12150:     }
                   12151:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12152:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12153:     
1.209     brouard  12154:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12155:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12156:     if (fage <= 2) {
                   12157:       bage = ageminpar;
                   12158:       fage = agemaxpar;
                   12159:     }
                   12160:     
                   12161:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12162:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12163:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12164:                
1.186     brouard  12165:     /* Other stuffs, more or less useful */    
1.254     brouard  12166:     while(fgets(line, MAXLINE, ficpar)) {
                   12167:       /* If line starts with a # it is a comment */
                   12168:       if (line[0] == '#') {
                   12169:        numlinepar++;
                   12170:        fputs(line,stdout);
                   12171:        fputs(line,ficparo);
                   12172:        fputs(line,ficlog);
                   12173:        continue;
                   12174:       }else
                   12175:        break;
                   12176:     }
                   12177: 
                   12178:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12179:       
                   12180:       if (num_filled != 7) {
                   12181:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12182:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12183:        goto end;
                   12184:       }
                   12185:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12186:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12187:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12188:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12189:     }
1.254     brouard  12190: 
                   12191:     while(fgets(line, MAXLINE, ficpar)) {
                   12192:       /* If line starts with a # it is a comment */
                   12193:       if (line[0] == '#') {
                   12194:        numlinepar++;
                   12195:        fputs(line,stdout);
                   12196:        fputs(line,ficparo);
                   12197:        fputs(line,ficlog);
                   12198:        continue;
                   12199:       }else
                   12200:        break;
1.126     brouard  12201:     }
                   12202:     
                   12203:     
                   12204:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12205:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12206:     
1.254     brouard  12207:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12208:       if (num_filled != 1) {
                   12209:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12210:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12211:        goto end;
                   12212:       }
                   12213:       printf("pop_based=%d\n",popbased);
                   12214:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12215:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12216:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12217:     }
                   12218:      
1.258     brouard  12219:     /* Results */
                   12220:     nresult=0;
                   12221:     do{
                   12222:       if(!fgets(line, MAXLINE, ficpar)){
                   12223:        endishere=1;
                   12224:        parameterline=14;
                   12225:       }else if (line[0] == '#') {
                   12226:        /* If line starts with a # it is a comment */
1.254     brouard  12227:        numlinepar++;
                   12228:        fputs(line,stdout);
                   12229:        fputs(line,ficparo);
                   12230:        fputs(line,ficlog);
                   12231:        continue;
1.258     brouard  12232:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12233:        parameterline=11;
                   12234:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12235:        parameterline=12;
                   12236:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12237:        parameterline=13;
                   12238:       else{
                   12239:        parameterline=14;
1.254     brouard  12240:       }
1.258     brouard  12241:       switch (parameterline){ 
                   12242:       case 11:
                   12243:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12244:          if (num_filled != 8) {
                   12245:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12246:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12247:            goto end;
                   12248:          }
                   12249:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12250:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12251:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12252:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12253:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12254:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12255:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12256: 
1.258     brouard  12257:        }
1.254     brouard  12258:        break;
1.258     brouard  12259:       case 12:
                   12260:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12261:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12262:          if (num_filled != 8) {
1.262     brouard  12263:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12264:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12265:            goto end;
                   12266:          }
                   12267:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12268:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12269:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12270:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12271:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12272:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12273:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12274:        }
1.230     brouard  12275:        break;
1.258     brouard  12276:       case 13:
                   12277:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12278:          if (num_filled == 0){
                   12279:            resultline[0]='\0';
                   12280:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12281:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12282:            break;
                   12283:          } else if (num_filled != 1){
                   12284:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12285:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12286:          }
                   12287:          nresult++; /* Sum of resultlines */
                   12288:          printf("Result %d: result=%s\n",nresult, resultline);
                   12289:          if(nresult > MAXRESULTLINES){
                   12290:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12291:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12292:            goto end;
                   12293:          }
                   12294:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12295:          fprintf(ficparo,"result: %s\n",resultline);
                   12296:          fprintf(ficres,"result: %s\n",resultline);
                   12297:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12298:          break;
1.258     brouard  12299:        case 14: 
1.259     brouard  12300:          if(ncovmodel >2 && nresult==0 ){
                   12301:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12302:            goto end;
                   12303:          }
1.259     brouard  12304:          break;
1.258     brouard  12305:        default:
                   12306:          nresult=1;
                   12307:          decoderesult(".",nresult ); /* No covariate */
                   12308:        }
                   12309:       } /* End switch parameterline */
                   12310:     }while(endishere==0); /* End do */
1.126     brouard  12311:     
1.230     brouard  12312:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12313:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12314:     
                   12315:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12316:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12317:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12318: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12319: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12320:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12321: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12322: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12323:     }else{
1.270     brouard  12324:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12325:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12326:     }
                   12327:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12328:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12329:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12330:                
1.225     brouard  12331:     /*------------ free_vector  -------------*/
                   12332:     /*  chdir(path); */
1.220     brouard  12333:                
1.215     brouard  12334:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12335:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12336:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12337:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.126     brouard  12338:     free_lvector(num,1,n);
                   12339:     free_vector(agedc,1,n);
                   12340:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12341:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12342:     fclose(ficparo);
                   12343:     fclose(ficres);
1.220     brouard  12344:                
                   12345:                
1.186     brouard  12346:     /* Other results (useful)*/
1.220     brouard  12347:                
                   12348:                
1.126     brouard  12349:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12350:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12351:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12352:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12353:     fclose(ficrespl);
                   12354: 
                   12355:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12356:     /*#include "hpijx.h"*/
                   12357:     hPijx(p, bage, fage);
1.145     brouard  12358:     fclose(ficrespij);
1.227     brouard  12359:     
1.220     brouard  12360:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12361:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12362:     k=1;
1.126     brouard  12363:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12364:     
1.269     brouard  12365:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12366:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12367:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12368:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12369:        for(k=1;k<=ncovcombmax;k++)
                   12370:          probs[i][j][k]=0.;
1.269     brouard  12371:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12372:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12373:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12374:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12375:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12376:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12377:          for(k=1;k<=ncovcombmax;k++)
                   12378:            mobaverages[i][j][k]=0.;
1.219     brouard  12379:       mobaverage=mobaverages;
                   12380:       if (mobilav!=0) {
1.235     brouard  12381:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12382:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12383:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12384:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12385:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12386:        }
1.269     brouard  12387:       } else if (mobilavproj !=0) {
1.235     brouard  12388:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12389:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12390:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12391:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12392:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12393:        }
1.269     brouard  12394:       }else{
                   12395:        printf("Internal error moving average\n");
                   12396:        fflush(stdout);
                   12397:        exit(1);
1.219     brouard  12398:       }
                   12399:     }/* end if moving average */
1.227     brouard  12400:     
1.126     brouard  12401:     /*---------- Forecasting ------------------*/
                   12402:     if(prevfcast==1){
                   12403:       /*    if(stepm ==1){*/
1.269     brouard  12404:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12405:     }
1.269     brouard  12406: 
                   12407:     /* Backcasting */
1.217     brouard  12408:     if(backcast==1){
1.219     brouard  12409:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12410:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12411:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12412: 
                   12413:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12414: 
                   12415:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12416: 
1.219     brouard  12417:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12418:       fclose(ficresplb);
                   12419: 
1.222     brouard  12420:       hBijx(p, bage, fage, mobaverage);
                   12421:       fclose(ficrespijb);
1.219     brouard  12422: 
1.269     brouard  12423:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12424:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12425:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12426: 
                   12427:       
1.269     brouard  12428:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12429:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12430:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12431:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12432:     }    /* end  Backcasting */
1.268     brouard  12433:  
1.186     brouard  12434:  
                   12435:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12436: 
1.215     brouard  12437:     free_ivector(wav,1,imx);
                   12438:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12439:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12440:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12441:                
                   12442:                
1.127     brouard  12443:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12444:                
1.201     brouard  12445:     strcpy(filerese,"E_");
                   12446:     strcat(filerese,fileresu);
1.126     brouard  12447:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12448:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12449:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12450:     }
1.208     brouard  12451:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12452:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12453: 
                   12454:     pstamp(ficreseij);
1.219     brouard  12455:                
1.235     brouard  12456:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12457:     if (cptcovn < 1){i1=1;}
                   12458:     
                   12459:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12460:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12461:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12462:        continue;
1.219     brouard  12463:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12464:       printf("\n#****** ");
1.225     brouard  12465:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12466:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12467:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12468:       }
                   12469:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12470:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12471:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12472:       }
                   12473:       fprintf(ficreseij,"******\n");
1.235     brouard  12474:       printf("******\n");
1.219     brouard  12475:       
                   12476:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12477:       oldm=oldms;savm=savms;
1.235     brouard  12478:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12479:       
1.219     brouard  12480:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12481:     }
                   12482:     fclose(ficreseij);
1.208     brouard  12483:     printf("done evsij\n");fflush(stdout);
                   12484:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12485: 
1.218     brouard  12486:                
1.227     brouard  12487:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12488:                
1.201     brouard  12489:     strcpy(filerest,"T_");
                   12490:     strcat(filerest,fileresu);
1.127     brouard  12491:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12492:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12493:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12494:     }
1.208     brouard  12495:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12496:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12497:     strcpy(fileresstde,"STDE_");
                   12498:     strcat(fileresstde,fileresu);
1.126     brouard  12499:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12500:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12501:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12502:     }
1.227     brouard  12503:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12504:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12505: 
1.201     brouard  12506:     strcpy(filerescve,"CVE_");
                   12507:     strcat(filerescve,fileresu);
1.126     brouard  12508:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12509:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12510:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12511:     }
1.227     brouard  12512:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12513:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12514: 
1.201     brouard  12515:     strcpy(fileresv,"V_");
                   12516:     strcat(fileresv,fileresu);
1.126     brouard  12517:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12518:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12519:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12520:     }
1.227     brouard  12521:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12522:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12523: 
1.235     brouard  12524:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12525:     if (cptcovn < 1){i1=1;}
                   12526:     
                   12527:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12528:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12529:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12530:        continue;
1.242     brouard  12531:       printf("\n#****** Result for:");
                   12532:       fprintf(ficrest,"\n#****** Result for:");
                   12533:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12534:       for(j=1;j<=cptcoveff;j++){ 
                   12535:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12536:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12537:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12538:       }
1.235     brouard  12539:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12540:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12541:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12542:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12543:       }        
1.208     brouard  12544:       fprintf(ficrest,"******\n");
1.227     brouard  12545:       fprintf(ficlog,"******\n");
                   12546:       printf("******\n");
1.208     brouard  12547:       
                   12548:       fprintf(ficresstdeij,"\n#****** ");
                   12549:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12550:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12551:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12552:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12553:       }
1.235     brouard  12554:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12555:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12556:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12557:       }        
1.208     brouard  12558:       fprintf(ficresstdeij,"******\n");
                   12559:       fprintf(ficrescveij,"******\n");
                   12560:       
                   12561:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12562:       /* pstamp(ficresvij); */
1.225     brouard  12563:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12564:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12565:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12566:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12567:       }        
1.208     brouard  12568:       fprintf(ficresvij,"******\n");
                   12569:       
                   12570:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12571:       oldm=oldms;savm=savms;
1.235     brouard  12572:       printf(" cvevsij ");
                   12573:       fprintf(ficlog, " cvevsij ");
                   12574:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12575:       printf(" end cvevsij \n ");
                   12576:       fprintf(ficlog, " end cvevsij \n ");
                   12577:       
                   12578:       /*
                   12579:        */
                   12580:       /* goto endfree; */
                   12581:       
                   12582:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12583:       pstamp(ficrest);
                   12584:       
1.269     brouard  12585:       epj=vector(1,nlstate+1);
1.208     brouard  12586:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12587:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12588:        cptcod= 0; /* To be deleted */
                   12589:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12590:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12591:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12592:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12593:        if(vpopbased==1)
                   12594:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12595:        else
1.288     brouard  12596:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12597:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12598:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12599:        fprintf(ficrest,"\n");
                   12600:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12601:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12602:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12603:        for(age=bage; age <=fage ;age++){
1.235     brouard  12604:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12605:          if (vpopbased==1) {
                   12606:            if(mobilav ==0){
                   12607:              for(i=1; i<=nlstate;i++)
                   12608:                prlim[i][i]=probs[(int)age][i][k];
                   12609:            }else{ /* mobilav */ 
                   12610:              for(i=1; i<=nlstate;i++)
                   12611:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12612:            }
                   12613:          }
1.219     brouard  12614:          
1.227     brouard  12615:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12616:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12617:          /* printf(" age %4.0f ",age); */
                   12618:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12619:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12620:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12621:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12622:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12623:            }
                   12624:            epj[nlstate+1] +=epj[j];
                   12625:          }
                   12626:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12627:          
1.227     brouard  12628:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12629:            for(j=1;j <=nlstate;j++)
                   12630:              vepp += vareij[i][j][(int)age];
                   12631:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12632:          for(j=1;j <=nlstate;j++){
                   12633:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12634:          }
                   12635:          fprintf(ficrest,"\n");
                   12636:        }
1.208     brouard  12637:       } /* End vpopbased */
1.269     brouard  12638:       free_vector(epj,1,nlstate+1);
1.208     brouard  12639:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12640:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12641:       printf("done selection\n");fflush(stdout);
                   12642:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12643:       
1.235     brouard  12644:     } /* End k selection */
1.227     brouard  12645: 
                   12646:     printf("done State-specific expectancies\n");fflush(stdout);
                   12647:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12648: 
1.288     brouard  12649:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12650:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12651: 
1.227     brouard  12652:     
                   12653:     free_vector(weight,1,n);
                   12654:     free_imatrix(Tvard,1,NCOVMAX,1,2);
                   12655:     free_imatrix(s,1,maxwav+1,1,n);
                   12656:     free_matrix(anint,1,maxwav,1,n); 
                   12657:     free_matrix(mint,1,maxwav,1,n);
                   12658:     free_ivector(cod,1,n);
                   12659:     free_ivector(tab,1,NCOVMAX);
                   12660:     fclose(ficresstdeij);
                   12661:     fclose(ficrescveij);
                   12662:     fclose(ficresvij);
                   12663:     fclose(ficrest);
                   12664:     fclose(ficpar);
                   12665:     
                   12666:     
1.126     brouard  12667:     /*---------- End : free ----------------*/
1.219     brouard  12668:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12669:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12670:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12671:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12672:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12673:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12674:   /* endfree:*/
                   12675:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12676:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12677:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.268     brouard  12678:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,1,n);
                   12679:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,1,n);
                   12680:   if(nqv>=1)free_matrix(coqvar,1,nqv,1,n);
1.227     brouard  12681:   free_matrix(covar,0,NCOVMAX,1,n);
                   12682:   free_matrix(matcov,1,npar,1,npar);
                   12683:   free_matrix(hess,1,npar,1,npar);
                   12684:   /*free_vector(delti,1,npar);*/
                   12685:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12686:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12687:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12688:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12689:   
                   12690:   free_ivector(ncodemax,1,NCOVMAX);
                   12691:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12692:   free_ivector(Dummy,-1,NCOVMAX);
                   12693:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12694:   free_ivector(DummyV,1,NCOVMAX);
                   12695:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12696:   free_ivector(Typevar,-1,NCOVMAX);
                   12697:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12698:   free_ivector(TvarsQ,1,NCOVMAX);
                   12699:   free_ivector(TvarsQind,1,NCOVMAX);
                   12700:   free_ivector(TvarsD,1,NCOVMAX);
                   12701:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12702:   free_ivector(TvarFD,1,NCOVMAX);
                   12703:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12704:   free_ivector(TvarF,1,NCOVMAX);
                   12705:   free_ivector(TvarFind,1,NCOVMAX);
                   12706:   free_ivector(TvarV,1,NCOVMAX);
                   12707:   free_ivector(TvarVind,1,NCOVMAX);
                   12708:   free_ivector(TvarA,1,NCOVMAX);
                   12709:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12710:   free_ivector(TvarFQ,1,NCOVMAX);
                   12711:   free_ivector(TvarFQind,1,NCOVMAX);
                   12712:   free_ivector(TvarVD,1,NCOVMAX);
                   12713:   free_ivector(TvarVDind,1,NCOVMAX);
                   12714:   free_ivector(TvarVQ,1,NCOVMAX);
                   12715:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12716:   free_ivector(Tvarsel,1,NCOVMAX);
                   12717:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12718:   free_ivector(Tposprod,1,NCOVMAX);
                   12719:   free_ivector(Tprod,1,NCOVMAX);
                   12720:   free_ivector(Tvaraff,1,NCOVMAX);
                   12721:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12722:   free_ivector(Tage,1,NCOVMAX);
                   12723:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12724:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12725:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12726:   
                   12727:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12728:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12729:   fflush(fichtm);
                   12730:   fflush(ficgp);
                   12731:   
1.227     brouard  12732:   
1.126     brouard  12733:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12734:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12735:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12736:   }else{
                   12737:     printf("End of Imach\n");
                   12738:     fprintf(ficlog,"End of Imach\n");
                   12739:   }
                   12740:   printf("See log file on %s\n",filelog);
                   12741:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12742:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12743:   rend_time = time(NULL);  
                   12744:   end_time = *localtime(&rend_time);
                   12745:   /* tml = *localtime(&end_time.tm_sec); */
                   12746:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12747:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12748:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12749:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12750:   
1.157     brouard  12751:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12752:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12753:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12754:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12755: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12756:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12757:   fclose(fichtm);
                   12758:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12759:   fclose(fichtmcov);
                   12760:   fclose(ficgp);
                   12761:   fclose(ficlog);
                   12762:   /*------ End -----------*/
1.227     brouard  12763:   
1.281     brouard  12764: 
                   12765: /* Executes gnuplot */
1.227     brouard  12766:   
                   12767:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12768: #ifdef WIN32
1.227     brouard  12769:   if (_chdir(pathcd) != 0)
                   12770:     printf("Can't move to directory %s!\n",path);
                   12771:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12772: #else
1.227     brouard  12773:     if(chdir(pathcd) != 0)
                   12774:       printf("Can't move to directory %s!\n", path);
                   12775:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12776: #endif 
1.126     brouard  12777:     printf("Current directory %s!\n",pathcd);
                   12778:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12779:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12780: #ifdef _WIN32
1.126     brouard  12781:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12782: #endif
                   12783:   if(!stat(plotcmd,&info)){
1.158     brouard  12784:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12785:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12786:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12787:     }else
                   12788:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12789: #ifdef __unix
1.126     brouard  12790:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12791:     if(!stat(plotcmd,&info)){
1.158     brouard  12792:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12793:     }else
                   12794:       strcpy(pplotcmd,plotcmd);
                   12795: #endif
                   12796:   }else
                   12797:     strcpy(pplotcmd,plotcmd);
                   12798:   
                   12799:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12800:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12801:   
1.126     brouard  12802:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12803:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12804:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12805:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12806:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12807:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12808:   }
1.158     brouard  12809:   printf(" Successful, please wait...");
1.126     brouard  12810:   while (z[0] != 'q') {
                   12811:     /* chdir(path); */
1.154     brouard  12812:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12813:     scanf("%s",z);
                   12814: /*     if (z[0] == 'c') system("./imach"); */
                   12815:     if (z[0] == 'e') {
1.158     brouard  12816: #ifdef __APPLE__
1.152     brouard  12817:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12818: #elif __linux
                   12819:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12820: #else
1.152     brouard  12821:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12822: #endif
                   12823:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12824:       system(pplotcmd);
1.126     brouard  12825:     }
                   12826:     else if (z[0] == 'g') system(plotcmd);
                   12827:     else if (z[0] == 'q') exit(0);
                   12828:   }
1.227     brouard  12829: end:
1.126     brouard  12830:   while (z[0] != 'q') {
1.195     brouard  12831:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12832:     scanf("%s",z);
                   12833:   }
1.283     brouard  12834:   printf("End\n");
1.282     brouard  12835:   exit(0);
1.126     brouard  12836: }

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