Annotation of imach/src/imach.c, revision 1.302

1.302   ! brouard     1: /* $Id: imach.c,v 1.301 2019/06/04 13:51:20 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.302   ! brouard     4:   Revision 1.301  2019/06/04 13:51:20  brouard
        !             5:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
        !             6: 
1.301     brouard     7:   Revision 1.300  2019/05/22 19:09:45  brouard
                      8:   Summary: version 0.99r19 of May 2019
                      9: 
1.300     brouard    10:   Revision 1.299  2019/05/22 18:37:08  brouard
                     11:   Summary: Cleaned 0.99r19
                     12: 
1.299     brouard    13:   Revision 1.298  2019/05/22 18:19:56  brouard
                     14:   *** empty log message ***
                     15: 
1.298     brouard    16:   Revision 1.297  2019/05/22 17:56:10  brouard
                     17:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     18: 
1.297     brouard    19:   Revision 1.296  2019/05/20 13:03:18  brouard
                     20:   Summary: Projection syntax simplified
                     21: 
                     22: 
                     23:   We can now start projections, forward or backward, from the mean date
                     24:   of inteviews up to or down to a number of years of projection:
                     25:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                     26:   or
                     27:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                     28:   or
                     29:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                     30:   or
                     31:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                     32: 
1.296     brouard    33:   Revision 1.295  2019/05/18 09:52:50  brouard
                     34:   Summary: doxygen tex bug
                     35: 
1.295     brouard    36:   Revision 1.294  2019/05/16 14:54:33  brouard
                     37:   Summary: There was some wrong lines added
                     38: 
1.294     brouard    39:   Revision 1.293  2019/05/09 15:17:34  brouard
                     40:   *** empty log message ***
                     41: 
1.293     brouard    42:   Revision 1.292  2019/05/09 14:17:20  brouard
                     43:   Summary: Some updates
                     44: 
1.292     brouard    45:   Revision 1.291  2019/05/09 13:44:18  brouard
                     46:   Summary: Before ncovmax
                     47: 
1.291     brouard    48:   Revision 1.290  2019/05/09 13:39:37  brouard
                     49:   Summary: 0.99r18 unlimited number of individuals
                     50: 
                     51:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                     52: 
1.290     brouard    53:   Revision 1.289  2018/12/13 09:16:26  brouard
                     54:   Summary: Bug for young ages (<-30) will be in r17
                     55: 
1.289     brouard    56:   Revision 1.288  2018/05/02 20:58:27  brouard
                     57:   Summary: Some bugs fixed
                     58: 
1.288     brouard    59:   Revision 1.287  2018/05/01 17:57:25  brouard
                     60:   Summary: Bug fixed by providing frequencies only for non missing covariates
                     61: 
1.287     brouard    62:   Revision 1.286  2018/04/27 14:27:04  brouard
                     63:   Summary: some minor bugs
                     64: 
1.286     brouard    65:   Revision 1.285  2018/04/21 21:02:16  brouard
                     66:   Summary: Some bugs fixed, valgrind tested
                     67: 
1.285     brouard    68:   Revision 1.284  2018/04/20 05:22:13  brouard
                     69:   Summary: Computing mean and stdeviation of fixed quantitative variables
                     70: 
1.284     brouard    71:   Revision 1.283  2018/04/19 14:49:16  brouard
                     72:   Summary: Some minor bugs fixed
                     73: 
1.283     brouard    74:   Revision 1.282  2018/02/27 22:50:02  brouard
                     75:   *** empty log message ***
                     76: 
1.282     brouard    77:   Revision 1.281  2018/02/27 19:25:23  brouard
                     78:   Summary: Adding second argument for quitting
                     79: 
1.281     brouard    80:   Revision 1.280  2018/02/21 07:58:13  brouard
                     81:   Summary: 0.99r15
                     82: 
                     83:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     84: 
1.280     brouard    85:   Revision 1.279  2017/07/20 13:35:01  brouard
                     86:   Summary: temporary working
                     87: 
1.279     brouard    88:   Revision 1.278  2017/07/19 14:09:02  brouard
                     89:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     90: 
1.278     brouard    91:   Revision 1.277  2017/07/17 08:53:49  brouard
                     92:   Summary: BOM files can be read now
                     93: 
1.277     brouard    94:   Revision 1.276  2017/06/30 15:48:31  brouard
                     95:   Summary: Graphs improvements
                     96: 
1.276     brouard    97:   Revision 1.275  2017/06/30 13:39:33  brouard
                     98:   Summary: Saito's color
                     99: 
1.275     brouard   100:   Revision 1.274  2017/06/29 09:47:08  brouard
                    101:   Summary: Version 0.99r14
                    102: 
1.274     brouard   103:   Revision 1.273  2017/06/27 11:06:02  brouard
                    104:   Summary: More documentation on projections
                    105: 
1.273     brouard   106:   Revision 1.272  2017/06/27 10:22:40  brouard
                    107:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    108: 
1.272     brouard   109:   Revision 1.271  2017/06/27 10:17:50  brouard
                    110:   Summary: Some bug with rint
                    111: 
1.271     brouard   112:   Revision 1.270  2017/05/24 05:45:29  brouard
                    113:   *** empty log message ***
                    114: 
1.270     brouard   115:   Revision 1.269  2017/05/23 08:39:25  brouard
                    116:   Summary: Code into subroutine, cleanings
                    117: 
1.269     brouard   118:   Revision 1.268  2017/05/18 20:09:32  brouard
                    119:   Summary: backprojection and confidence intervals of backprevalence
                    120: 
1.268     brouard   121:   Revision 1.267  2017/05/13 10:25:05  brouard
                    122:   Summary: temporary save for backprojection
                    123: 
1.267     brouard   124:   Revision 1.266  2017/05/13 07:26:12  brouard
                    125:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    126: 
1.266     brouard   127:   Revision 1.265  2017/04/26 16:22:11  brouard
                    128:   Summary: imach 0.99r13 Some bugs fixed
                    129: 
1.265     brouard   130:   Revision 1.264  2017/04/26 06:01:29  brouard
                    131:   Summary: Labels in graphs
                    132: 
1.264     brouard   133:   Revision 1.263  2017/04/24 15:23:15  brouard
                    134:   Summary: to save
                    135: 
1.263     brouard   136:   Revision 1.262  2017/04/18 16:48:12  brouard
                    137:   *** empty log message ***
                    138: 
1.262     brouard   139:   Revision 1.261  2017/04/05 10:14:09  brouard
                    140:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    141: 
1.261     brouard   142:   Revision 1.260  2017/04/04 17:46:59  brouard
                    143:   Summary: Gnuplot indexations fixed (humm)
                    144: 
1.260     brouard   145:   Revision 1.259  2017/04/04 13:01:16  brouard
                    146:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    147: 
1.259     brouard   148:   Revision 1.258  2017/04/03 10:17:47  brouard
                    149:   Summary: Version 0.99r12
                    150: 
                    151:   Some cleanings, conformed with updated documentation.
                    152: 
1.258     brouard   153:   Revision 1.257  2017/03/29 16:53:30  brouard
                    154:   Summary: Temp
                    155: 
1.257     brouard   156:   Revision 1.256  2017/03/27 05:50:23  brouard
                    157:   Summary: Temporary
                    158: 
1.256     brouard   159:   Revision 1.255  2017/03/08 16:02:28  brouard
                    160:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    161: 
1.255     brouard   162:   Revision 1.254  2017/03/08 07:13:00  brouard
                    163:   Summary: Fixing data parameter line
                    164: 
1.254     brouard   165:   Revision 1.253  2016/12/15 11:59:41  brouard
                    166:   Summary: 0.99 in progress
                    167: 
1.253     brouard   168:   Revision 1.252  2016/09/15 21:15:37  brouard
                    169:   *** empty log message ***
                    170: 
1.252     brouard   171:   Revision 1.251  2016/09/15 15:01:13  brouard
                    172:   Summary: not working
                    173: 
1.251     brouard   174:   Revision 1.250  2016/09/08 16:07:27  brouard
                    175:   Summary: continue
                    176: 
1.250     brouard   177:   Revision 1.249  2016/09/07 17:14:18  brouard
                    178:   Summary: Starting values from frequencies
                    179: 
1.249     brouard   180:   Revision 1.248  2016/09/07 14:10:18  brouard
                    181:   *** empty log message ***
                    182: 
1.248     brouard   183:   Revision 1.247  2016/09/02 11:11:21  brouard
                    184:   *** empty log message ***
                    185: 
1.247     brouard   186:   Revision 1.246  2016/09/02 08:49:22  brouard
                    187:   *** empty log message ***
                    188: 
1.246     brouard   189:   Revision 1.245  2016/09/02 07:25:01  brouard
                    190:   *** empty log message ***
                    191: 
1.245     brouard   192:   Revision 1.244  2016/09/02 07:17:34  brouard
                    193:   *** empty log message ***
                    194: 
1.244     brouard   195:   Revision 1.243  2016/09/02 06:45:35  brouard
                    196:   *** empty log message ***
                    197: 
1.243     brouard   198:   Revision 1.242  2016/08/30 15:01:20  brouard
                    199:   Summary: Fixing a lots
                    200: 
1.242     brouard   201:   Revision 1.241  2016/08/29 17:17:25  brouard
                    202:   Summary: gnuplot problem in Back projection to fix
                    203: 
1.241     brouard   204:   Revision 1.240  2016/08/29 07:53:18  brouard
                    205:   Summary: Better
                    206: 
1.240     brouard   207:   Revision 1.239  2016/08/26 15:51:03  brouard
                    208:   Summary: Improvement in Powell output in order to copy and paste
                    209: 
                    210:   Author:
                    211: 
1.239     brouard   212:   Revision 1.238  2016/08/26 14:23:35  brouard
                    213:   Summary: Starting tests of 0.99
                    214: 
1.238     brouard   215:   Revision 1.237  2016/08/26 09:20:19  brouard
                    216:   Summary: to valgrind
                    217: 
1.237     brouard   218:   Revision 1.236  2016/08/25 10:50:18  brouard
                    219:   *** empty log message ***
                    220: 
1.236     brouard   221:   Revision 1.235  2016/08/25 06:59:23  brouard
                    222:   *** empty log message ***
                    223: 
1.235     brouard   224:   Revision 1.234  2016/08/23 16:51:20  brouard
                    225:   *** empty log message ***
                    226: 
1.234     brouard   227:   Revision 1.233  2016/08/23 07:40:50  brouard
                    228:   Summary: not working
                    229: 
1.233     brouard   230:   Revision 1.232  2016/08/22 14:20:21  brouard
                    231:   Summary: not working
                    232: 
1.232     brouard   233:   Revision 1.231  2016/08/22 07:17:15  brouard
                    234:   Summary: not working
                    235: 
1.231     brouard   236:   Revision 1.230  2016/08/22 06:55:53  brouard
                    237:   Summary: Not working
                    238: 
1.230     brouard   239:   Revision 1.229  2016/07/23 09:45:53  brouard
                    240:   Summary: Completing for func too
                    241: 
1.229     brouard   242:   Revision 1.228  2016/07/22 17:45:30  brouard
                    243:   Summary: Fixing some arrays, still debugging
                    244: 
1.227     brouard   245:   Revision 1.226  2016/07/12 18:42:34  brouard
                    246:   Summary: temp
                    247: 
1.226     brouard   248:   Revision 1.225  2016/07/12 08:40:03  brouard
                    249:   Summary: saving but not running
                    250: 
1.225     brouard   251:   Revision 1.224  2016/07/01 13:16:01  brouard
                    252:   Summary: Fixes
                    253: 
1.224     brouard   254:   Revision 1.223  2016/02/19 09:23:35  brouard
                    255:   Summary: temporary
                    256: 
1.223     brouard   257:   Revision 1.222  2016/02/17 08:14:50  brouard
                    258:   Summary: Probably last 0.98 stable version 0.98r6
                    259: 
1.222     brouard   260:   Revision 1.221  2016/02/15 23:35:36  brouard
                    261:   Summary: minor bug
                    262: 
1.220     brouard   263:   Revision 1.219  2016/02/15 00:48:12  brouard
                    264:   *** empty log message ***
                    265: 
1.219     brouard   266:   Revision 1.218  2016/02/12 11:29:23  brouard
                    267:   Summary: 0.99 Back projections
                    268: 
1.218     brouard   269:   Revision 1.217  2015/12/23 17:18:31  brouard
                    270:   Summary: Experimental backcast
                    271: 
1.217     brouard   272:   Revision 1.216  2015/12/18 17:32:11  brouard
                    273:   Summary: 0.98r4 Warning and status=-2
                    274: 
                    275:   Version 0.98r4 is now:
                    276:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    277:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    278:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    279: 
1.216     brouard   280:   Revision 1.215  2015/12/16 08:52:24  brouard
                    281:   Summary: 0.98r4 working
                    282: 
1.215     brouard   283:   Revision 1.214  2015/12/16 06:57:54  brouard
                    284:   Summary: temporary not working
                    285: 
1.214     brouard   286:   Revision 1.213  2015/12/11 18:22:17  brouard
                    287:   Summary: 0.98r4
                    288: 
1.213     brouard   289:   Revision 1.212  2015/11/21 12:47:24  brouard
                    290:   Summary: minor typo
                    291: 
1.212     brouard   292:   Revision 1.211  2015/11/21 12:41:11  brouard
                    293:   Summary: 0.98r3 with some graph of projected cross-sectional
                    294: 
                    295:   Author: Nicolas Brouard
                    296: 
1.211     brouard   297:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   298:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   299:   Summary: Adding ftolpl parameter
                    300:   Author: N Brouard
                    301: 
                    302:   We had difficulties to get smoothed confidence intervals. It was due
                    303:   to the period prevalence which wasn't computed accurately. The inner
                    304:   parameter ftolpl is now an outer parameter of the .imach parameter
                    305:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    306:   computation are long.
                    307: 
1.209     brouard   308:   Revision 1.208  2015/11/17 14:31:57  brouard
                    309:   Summary: temporary
                    310: 
1.208     brouard   311:   Revision 1.207  2015/10/27 17:36:57  brouard
                    312:   *** empty log message ***
                    313: 
1.207     brouard   314:   Revision 1.206  2015/10/24 07:14:11  brouard
                    315:   *** empty log message ***
                    316: 
1.206     brouard   317:   Revision 1.205  2015/10/23 15:50:53  brouard
                    318:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    319: 
1.205     brouard   320:   Revision 1.204  2015/10/01 16:20:26  brouard
                    321:   Summary: Some new graphs of contribution to likelihood
                    322: 
1.204     brouard   323:   Revision 1.203  2015/09/30 17:45:14  brouard
                    324:   Summary: looking at better estimation of the hessian
                    325: 
                    326:   Also a better criteria for convergence to the period prevalence And
                    327:   therefore adding the number of years needed to converge. (The
                    328:   prevalence in any alive state shold sum to one
                    329: 
1.203     brouard   330:   Revision 1.202  2015/09/22 19:45:16  brouard
                    331:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    332: 
1.202     brouard   333:   Revision 1.201  2015/09/15 17:34:58  brouard
                    334:   Summary: 0.98r0
                    335: 
                    336:   - Some new graphs like suvival functions
                    337:   - Some bugs fixed like model=1+age+V2.
                    338: 
1.201     brouard   339:   Revision 1.200  2015/09/09 16:53:55  brouard
                    340:   Summary: Big bug thanks to Flavia
                    341: 
                    342:   Even model=1+age+V2. did not work anymore
                    343: 
1.200     brouard   344:   Revision 1.199  2015/09/07 14:09:23  brouard
                    345:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    346: 
1.199     brouard   347:   Revision 1.198  2015/09/03 07:14:39  brouard
                    348:   Summary: 0.98q5 Flavia
                    349: 
1.198     brouard   350:   Revision 1.197  2015/09/01 18:24:39  brouard
                    351:   *** empty log message ***
                    352: 
1.197     brouard   353:   Revision 1.196  2015/08/18 23:17:52  brouard
                    354:   Summary: 0.98q5
                    355: 
1.196     brouard   356:   Revision 1.195  2015/08/18 16:28:39  brouard
                    357:   Summary: Adding a hack for testing purpose
                    358: 
                    359:   After reading the title, ftol and model lines, if the comment line has
                    360:   a q, starting with #q, the answer at the end of the run is quit. It
                    361:   permits to run test files in batch with ctest. The former workaround was
                    362:   $ echo q | imach foo.imach
                    363: 
1.195     brouard   364:   Revision 1.194  2015/08/18 13:32:00  brouard
                    365:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    366: 
1.194     brouard   367:   Revision 1.193  2015/08/04 07:17:42  brouard
                    368:   Summary: 0.98q4
                    369: 
1.193     brouard   370:   Revision 1.192  2015/07/16 16:49:02  brouard
                    371:   Summary: Fixing some outputs
                    372: 
1.192     brouard   373:   Revision 1.191  2015/07/14 10:00:33  brouard
                    374:   Summary: Some fixes
                    375: 
1.191     brouard   376:   Revision 1.190  2015/05/05 08:51:13  brouard
                    377:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    378: 
                    379:   Fix 1+age+.
                    380: 
1.190     brouard   381:   Revision 1.189  2015/04/30 14:45:16  brouard
                    382:   Summary: 0.98q2
                    383: 
1.189     brouard   384:   Revision 1.188  2015/04/30 08:27:53  brouard
                    385:   *** empty log message ***
                    386: 
1.188     brouard   387:   Revision 1.187  2015/04/29 09:11:15  brouard
                    388:   *** empty log message ***
                    389: 
1.187     brouard   390:   Revision 1.186  2015/04/23 12:01:52  brouard
                    391:   Summary: V1*age is working now, version 0.98q1
                    392: 
                    393:   Some codes had been disabled in order to simplify and Vn*age was
                    394:   working in the optimization phase, ie, giving correct MLE parameters,
                    395:   but, as usual, outputs were not correct and program core dumped.
                    396: 
1.186     brouard   397:   Revision 1.185  2015/03/11 13:26:42  brouard
                    398:   Summary: Inclusion of compile and links command line for Intel Compiler
                    399: 
1.185     brouard   400:   Revision 1.184  2015/03/11 11:52:39  brouard
                    401:   Summary: Back from Windows 8. Intel Compiler
                    402: 
1.184     brouard   403:   Revision 1.183  2015/03/10 20:34:32  brouard
                    404:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    405: 
                    406:   We use directest instead of original Powell test; probably no
                    407:   incidence on the results, but better justifications;
                    408:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    409:   wrong results.
                    410: 
1.183     brouard   411:   Revision 1.182  2015/02/12 08:19:57  brouard
                    412:   Summary: Trying to keep directest which seems simpler and more general
                    413:   Author: Nicolas Brouard
                    414: 
1.182     brouard   415:   Revision 1.181  2015/02/11 23:22:24  brouard
                    416:   Summary: Comments on Powell added
                    417: 
                    418:   Author:
                    419: 
1.181     brouard   420:   Revision 1.180  2015/02/11 17:33:45  brouard
                    421:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    422: 
1.180     brouard   423:   Revision 1.179  2015/01/04 09:57:06  brouard
                    424:   Summary: back to OS/X
                    425: 
1.179     brouard   426:   Revision 1.178  2015/01/04 09:35:48  brouard
                    427:   *** empty log message ***
                    428: 
1.178     brouard   429:   Revision 1.177  2015/01/03 18:40:56  brouard
                    430:   Summary: Still testing ilc32 on OSX
                    431: 
1.177     brouard   432:   Revision 1.176  2015/01/03 16:45:04  brouard
                    433:   *** empty log message ***
                    434: 
1.176     brouard   435:   Revision 1.175  2015/01/03 16:33:42  brouard
                    436:   *** empty log message ***
                    437: 
1.175     brouard   438:   Revision 1.174  2015/01/03 16:15:49  brouard
                    439:   Summary: Still in cross-compilation
                    440: 
1.174     brouard   441:   Revision 1.173  2015/01/03 12:06:26  brouard
                    442:   Summary: trying to detect cross-compilation
                    443: 
1.173     brouard   444:   Revision 1.172  2014/12/27 12:07:47  brouard
                    445:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    446: 
1.172     brouard   447:   Revision 1.171  2014/12/23 13:26:59  brouard
                    448:   Summary: Back from Visual C
                    449: 
                    450:   Still problem with utsname.h on Windows
                    451: 
1.171     brouard   452:   Revision 1.170  2014/12/23 11:17:12  brouard
                    453:   Summary: Cleaning some \%% back to %%
                    454: 
                    455:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    456: 
1.170     brouard   457:   Revision 1.169  2014/12/22 23:08:31  brouard
                    458:   Summary: 0.98p
                    459: 
                    460:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    461: 
1.169     brouard   462:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   463:   Summary: update
1.169     brouard   464: 
1.168     brouard   465:   Revision 1.167  2014/12/22 13:50:56  brouard
                    466:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    467: 
                    468:   Testing on Linux 64
                    469: 
1.167     brouard   470:   Revision 1.166  2014/12/22 11:40:47  brouard
                    471:   *** empty log message ***
                    472: 
1.166     brouard   473:   Revision 1.165  2014/12/16 11:20:36  brouard
                    474:   Summary: After compiling on Visual C
                    475: 
                    476:   * imach.c (Module): Merging 1.61 to 1.162
                    477: 
1.165     brouard   478:   Revision 1.164  2014/12/16 10:52:11  brouard
                    479:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    480: 
                    481:   * imach.c (Module): Merging 1.61 to 1.162
                    482: 
1.164     brouard   483:   Revision 1.163  2014/12/16 10:30:11  brouard
                    484:   * imach.c (Module): Merging 1.61 to 1.162
                    485: 
1.163     brouard   486:   Revision 1.162  2014/09/25 11:43:39  brouard
                    487:   Summary: temporary backup 0.99!
                    488: 
1.162     brouard   489:   Revision 1.1  2014/09/16 11:06:58  brouard
                    490:   Summary: With some code (wrong) for nlopt
                    491: 
                    492:   Author:
                    493: 
                    494:   Revision 1.161  2014/09/15 20:41:41  brouard
                    495:   Summary: Problem with macro SQR on Intel compiler
                    496: 
1.161     brouard   497:   Revision 1.160  2014/09/02 09:24:05  brouard
                    498:   *** empty log message ***
                    499: 
1.160     brouard   500:   Revision 1.159  2014/09/01 10:34:10  brouard
                    501:   Summary: WIN32
                    502:   Author: Brouard
                    503: 
1.159     brouard   504:   Revision 1.158  2014/08/27 17:11:51  brouard
                    505:   *** empty log message ***
                    506: 
1.158     brouard   507:   Revision 1.157  2014/08/27 16:26:55  brouard
                    508:   Summary: Preparing windows Visual studio version
                    509:   Author: Brouard
                    510: 
                    511:   In order to compile on Visual studio, time.h is now correct and time_t
                    512:   and tm struct should be used. difftime should be used but sometimes I
                    513:   just make the differences in raw time format (time(&now).
                    514:   Trying to suppress #ifdef LINUX
                    515:   Add xdg-open for __linux in order to open default browser.
                    516: 
1.157     brouard   517:   Revision 1.156  2014/08/25 20:10:10  brouard
                    518:   *** empty log message ***
                    519: 
1.156     brouard   520:   Revision 1.155  2014/08/25 18:32:34  brouard
                    521:   Summary: New compile, minor changes
                    522:   Author: Brouard
                    523: 
1.155     brouard   524:   Revision 1.154  2014/06/20 17:32:08  brouard
                    525:   Summary: Outputs now all graphs of convergence to period prevalence
                    526: 
1.154     brouard   527:   Revision 1.153  2014/06/20 16:45:46  brouard
                    528:   Summary: If 3 live state, convergence to period prevalence on same graph
                    529:   Author: Brouard
                    530: 
1.153     brouard   531:   Revision 1.152  2014/06/18 17:54:09  brouard
                    532:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    533: 
1.152     brouard   534:   Revision 1.151  2014/06/18 16:43:30  brouard
                    535:   *** empty log message ***
                    536: 
1.151     brouard   537:   Revision 1.150  2014/06/18 16:42:35  brouard
                    538:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    539:   Author: brouard
                    540: 
1.150     brouard   541:   Revision 1.149  2014/06/18 15:51:14  brouard
                    542:   Summary: Some fixes in parameter files errors
                    543:   Author: Nicolas Brouard
                    544: 
1.149     brouard   545:   Revision 1.148  2014/06/17 17:38:48  brouard
                    546:   Summary: Nothing new
                    547:   Author: Brouard
                    548: 
                    549:   Just a new packaging for OS/X version 0.98nS
                    550: 
1.148     brouard   551:   Revision 1.147  2014/06/16 10:33:11  brouard
                    552:   *** empty log message ***
                    553: 
1.147     brouard   554:   Revision 1.146  2014/06/16 10:20:28  brouard
                    555:   Summary: Merge
                    556:   Author: Brouard
                    557: 
                    558:   Merge, before building revised version.
                    559: 
1.146     brouard   560:   Revision 1.145  2014/06/10 21:23:15  brouard
                    561:   Summary: Debugging with valgrind
                    562:   Author: Nicolas Brouard
                    563: 
                    564:   Lot of changes in order to output the results with some covariates
                    565:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    566:   improve the code.
                    567:   No more memory valgrind error but a lot has to be done in order to
                    568:   continue the work of splitting the code into subroutines.
                    569:   Also, decodemodel has been improved. Tricode is still not
                    570:   optimal. nbcode should be improved. Documentation has been added in
                    571:   the source code.
                    572: 
1.144     brouard   573:   Revision 1.143  2014/01/26 09:45:38  brouard
                    574:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    575: 
                    576:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    577:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    578: 
1.143     brouard   579:   Revision 1.142  2014/01/26 03:57:36  brouard
                    580:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    581: 
                    582:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    583: 
1.142     brouard   584:   Revision 1.141  2014/01/26 02:42:01  brouard
                    585:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    586: 
1.141     brouard   587:   Revision 1.140  2011/09/02 10:37:54  brouard
                    588:   Summary: times.h is ok with mingw32 now.
                    589: 
1.140     brouard   590:   Revision 1.139  2010/06/14 07:50:17  brouard
                    591:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    592:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    593: 
1.139     brouard   594:   Revision 1.138  2010/04/30 18:19:40  brouard
                    595:   *** empty log message ***
                    596: 
1.138     brouard   597:   Revision 1.137  2010/04/29 18:11:38  brouard
                    598:   (Module): Checking covariates for more complex models
                    599:   than V1+V2. A lot of change to be done. Unstable.
                    600: 
1.137     brouard   601:   Revision 1.136  2010/04/26 20:30:53  brouard
                    602:   (Module): merging some libgsl code. Fixing computation
                    603:   of likelione (using inter/intrapolation if mle = 0) in order to
                    604:   get same likelihood as if mle=1.
                    605:   Some cleaning of code and comments added.
                    606: 
1.136     brouard   607:   Revision 1.135  2009/10/29 15:33:14  brouard
                    608:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    609: 
1.135     brouard   610:   Revision 1.134  2009/10/29 13:18:53  brouard
                    611:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    612: 
1.134     brouard   613:   Revision 1.133  2009/07/06 10:21:25  brouard
                    614:   just nforces
                    615: 
1.133     brouard   616:   Revision 1.132  2009/07/06 08:22:05  brouard
                    617:   Many tings
                    618: 
1.132     brouard   619:   Revision 1.131  2009/06/20 16:22:47  brouard
                    620:   Some dimensions resccaled
                    621: 
1.131     brouard   622:   Revision 1.130  2009/05/26 06:44:34  brouard
                    623:   (Module): Max Covariate is now set to 20 instead of 8. A
                    624:   lot of cleaning with variables initialized to 0. Trying to make
                    625:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    626: 
1.130     brouard   627:   Revision 1.129  2007/08/31 13:49:27  lievre
                    628:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    629: 
1.129     lievre    630:   Revision 1.128  2006/06/30 13:02:05  brouard
                    631:   (Module): Clarifications on computing e.j
                    632: 
1.128     brouard   633:   Revision 1.127  2006/04/28 18:11:50  brouard
                    634:   (Module): Yes the sum of survivors was wrong since
                    635:   imach-114 because nhstepm was no more computed in the age
                    636:   loop. Now we define nhstepma in the age loop.
                    637:   (Module): In order to speed up (in case of numerous covariates) we
                    638:   compute health expectancies (without variances) in a first step
                    639:   and then all the health expectancies with variances or standard
                    640:   deviation (needs data from the Hessian matrices) which slows the
                    641:   computation.
                    642:   In the future we should be able to stop the program is only health
                    643:   expectancies and graph are needed without standard deviations.
                    644: 
1.127     brouard   645:   Revision 1.126  2006/04/28 17:23:28  brouard
                    646:   (Module): Yes the sum of survivors was wrong since
                    647:   imach-114 because nhstepm was no more computed in the age
                    648:   loop. Now we define nhstepma in the age loop.
                    649:   Version 0.98h
                    650: 
1.126     brouard   651:   Revision 1.125  2006/04/04 15:20:31  lievre
                    652:   Errors in calculation of health expectancies. Age was not initialized.
                    653:   Forecasting file added.
                    654: 
                    655:   Revision 1.124  2006/03/22 17:13:53  lievre
                    656:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    657:   The log-likelihood is printed in the log file
                    658: 
                    659:   Revision 1.123  2006/03/20 10:52:43  brouard
                    660:   * imach.c (Module): <title> changed, corresponds to .htm file
                    661:   name. <head> headers where missing.
                    662: 
                    663:   * imach.c (Module): Weights can have a decimal point as for
                    664:   English (a comma might work with a correct LC_NUMERIC environment,
                    665:   otherwise the weight is truncated).
                    666:   Modification of warning when the covariates values are not 0 or
                    667:   1.
                    668:   Version 0.98g
                    669: 
                    670:   Revision 1.122  2006/03/20 09:45:41  brouard
                    671:   (Module): Weights can have a decimal point as for
                    672:   English (a comma might work with a correct LC_NUMERIC environment,
                    673:   otherwise the weight is truncated).
                    674:   Modification of warning when the covariates values are not 0 or
                    675:   1.
                    676:   Version 0.98g
                    677: 
                    678:   Revision 1.121  2006/03/16 17:45:01  lievre
                    679:   * imach.c (Module): Comments concerning covariates added
                    680: 
                    681:   * imach.c (Module): refinements in the computation of lli if
                    682:   status=-2 in order to have more reliable computation if stepm is
                    683:   not 1 month. Version 0.98f
                    684: 
                    685:   Revision 1.120  2006/03/16 15:10:38  lievre
                    686:   (Module): refinements in the computation of lli if
                    687:   status=-2 in order to have more reliable computation if stepm is
                    688:   not 1 month. Version 0.98f
                    689: 
                    690:   Revision 1.119  2006/03/15 17:42:26  brouard
                    691:   (Module): Bug if status = -2, the loglikelihood was
                    692:   computed as likelihood omitting the logarithm. Version O.98e
                    693: 
                    694:   Revision 1.118  2006/03/14 18:20:07  brouard
                    695:   (Module): varevsij Comments added explaining the second
                    696:   table of variances if popbased=1 .
                    697:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    698:   (Module): Function pstamp added
                    699:   (Module): Version 0.98d
                    700: 
                    701:   Revision 1.117  2006/03/14 17:16:22  brouard
                    702:   (Module): varevsij Comments added explaining the second
                    703:   table of variances if popbased=1 .
                    704:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    705:   (Module): Function pstamp added
                    706:   (Module): Version 0.98d
                    707: 
                    708:   Revision 1.116  2006/03/06 10:29:27  brouard
                    709:   (Module): Variance-covariance wrong links and
                    710:   varian-covariance of ej. is needed (Saito).
                    711: 
                    712:   Revision 1.115  2006/02/27 12:17:45  brouard
                    713:   (Module): One freematrix added in mlikeli! 0.98c
                    714: 
                    715:   Revision 1.114  2006/02/26 12:57:58  brouard
                    716:   (Module): Some improvements in processing parameter
                    717:   filename with strsep.
                    718: 
                    719:   Revision 1.113  2006/02/24 14:20:24  brouard
                    720:   (Module): Memory leaks checks with valgrind and:
                    721:   datafile was not closed, some imatrix were not freed and on matrix
                    722:   allocation too.
                    723: 
                    724:   Revision 1.112  2006/01/30 09:55:26  brouard
                    725:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    726: 
                    727:   Revision 1.111  2006/01/25 20:38:18  brouard
                    728:   (Module): Lots of cleaning and bugs added (Gompertz)
                    729:   (Module): Comments can be added in data file. Missing date values
                    730:   can be a simple dot '.'.
                    731: 
                    732:   Revision 1.110  2006/01/25 00:51:50  brouard
                    733:   (Module): Lots of cleaning and bugs added (Gompertz)
                    734: 
                    735:   Revision 1.109  2006/01/24 19:37:15  brouard
                    736:   (Module): Comments (lines starting with a #) are allowed in data.
                    737: 
                    738:   Revision 1.108  2006/01/19 18:05:42  lievre
                    739:   Gnuplot problem appeared...
                    740:   To be fixed
                    741: 
                    742:   Revision 1.107  2006/01/19 16:20:37  brouard
                    743:   Test existence of gnuplot in imach path
                    744: 
                    745:   Revision 1.106  2006/01/19 13:24:36  brouard
                    746:   Some cleaning and links added in html output
                    747: 
                    748:   Revision 1.105  2006/01/05 20:23:19  lievre
                    749:   *** empty log message ***
                    750: 
                    751:   Revision 1.104  2005/09/30 16:11:43  lievre
                    752:   (Module): sump fixed, loop imx fixed, and simplifications.
                    753:   (Module): If the status is missing at the last wave but we know
                    754:   that the person is alive, then we can code his/her status as -2
                    755:   (instead of missing=-1 in earlier versions) and his/her
                    756:   contributions to the likelihood is 1 - Prob of dying from last
                    757:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    758:   the healthy state at last known wave). Version is 0.98
                    759: 
                    760:   Revision 1.103  2005/09/30 15:54:49  lievre
                    761:   (Module): sump fixed, loop imx fixed, and simplifications.
                    762: 
                    763:   Revision 1.102  2004/09/15 17:31:30  brouard
                    764:   Add the possibility to read data file including tab characters.
                    765: 
                    766:   Revision 1.101  2004/09/15 10:38:38  brouard
                    767:   Fix on curr_time
                    768: 
                    769:   Revision 1.100  2004/07/12 18:29:06  brouard
                    770:   Add version for Mac OS X. Just define UNIX in Makefile
                    771: 
                    772:   Revision 1.99  2004/06/05 08:57:40  brouard
                    773:   *** empty log message ***
                    774: 
                    775:   Revision 1.98  2004/05/16 15:05:56  brouard
                    776:   New version 0.97 . First attempt to estimate force of mortality
                    777:   directly from the data i.e. without the need of knowing the health
                    778:   state at each age, but using a Gompertz model: log u =a + b*age .
                    779:   This is the basic analysis of mortality and should be done before any
                    780:   other analysis, in order to test if the mortality estimated from the
                    781:   cross-longitudinal survey is different from the mortality estimated
                    782:   from other sources like vital statistic data.
                    783: 
                    784:   The same imach parameter file can be used but the option for mle should be -3.
                    785: 
1.133     brouard   786:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   787:   former routines in order to include the new code within the former code.
                    788: 
                    789:   The output is very simple: only an estimate of the intercept and of
                    790:   the slope with 95% confident intervals.
                    791: 
                    792:   Current limitations:
                    793:   A) Even if you enter covariates, i.e. with the
                    794:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    795:   B) There is no computation of Life Expectancy nor Life Table.
                    796: 
                    797:   Revision 1.97  2004/02/20 13:25:42  lievre
                    798:   Version 0.96d. Population forecasting command line is (temporarily)
                    799:   suppressed.
                    800: 
                    801:   Revision 1.96  2003/07/15 15:38:55  brouard
                    802:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    803:   rewritten within the same printf. Workaround: many printfs.
                    804: 
                    805:   Revision 1.95  2003/07/08 07:54:34  brouard
                    806:   * imach.c (Repository):
                    807:   (Repository): Using imachwizard code to output a more meaningful covariance
                    808:   matrix (cov(a12,c31) instead of numbers.
                    809: 
                    810:   Revision 1.94  2003/06/27 13:00:02  brouard
                    811:   Just cleaning
                    812: 
                    813:   Revision 1.93  2003/06/25 16:33:55  brouard
                    814:   (Module): On windows (cygwin) function asctime_r doesn't
                    815:   exist so I changed back to asctime which exists.
                    816:   (Module): Version 0.96b
                    817: 
                    818:   Revision 1.92  2003/06/25 16:30:45  brouard
                    819:   (Module): On windows (cygwin) function asctime_r doesn't
                    820:   exist so I changed back to asctime which exists.
                    821: 
                    822:   Revision 1.91  2003/06/25 15:30:29  brouard
                    823:   * imach.c (Repository): Duplicated warning errors corrected.
                    824:   (Repository): Elapsed time after each iteration is now output. It
                    825:   helps to forecast when convergence will be reached. Elapsed time
                    826:   is stamped in powell.  We created a new html file for the graphs
                    827:   concerning matrix of covariance. It has extension -cov.htm.
                    828: 
                    829:   Revision 1.90  2003/06/24 12:34:15  brouard
                    830:   (Module): Some bugs corrected for windows. Also, when
                    831:   mle=-1 a template is output in file "or"mypar.txt with the design
                    832:   of the covariance matrix to be input.
                    833: 
                    834:   Revision 1.89  2003/06/24 12:30:52  brouard
                    835:   (Module): Some bugs corrected for windows. Also, when
                    836:   mle=-1 a template is output in file "or"mypar.txt with the design
                    837:   of the covariance matrix to be input.
                    838: 
                    839:   Revision 1.88  2003/06/23 17:54:56  brouard
                    840:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    841: 
                    842:   Revision 1.87  2003/06/18 12:26:01  brouard
                    843:   Version 0.96
                    844: 
                    845:   Revision 1.86  2003/06/17 20:04:08  brouard
                    846:   (Module): Change position of html and gnuplot routines and added
                    847:   routine fileappend.
                    848: 
                    849:   Revision 1.85  2003/06/17 13:12:43  brouard
                    850:   * imach.c (Repository): Check when date of death was earlier that
                    851:   current date of interview. It may happen when the death was just
                    852:   prior to the death. In this case, dh was negative and likelihood
                    853:   was wrong (infinity). We still send an "Error" but patch by
                    854:   assuming that the date of death was just one stepm after the
                    855:   interview.
                    856:   (Repository): Because some people have very long ID (first column)
                    857:   we changed int to long in num[] and we added a new lvector for
                    858:   memory allocation. But we also truncated to 8 characters (left
                    859:   truncation)
                    860:   (Repository): No more line truncation errors.
                    861: 
                    862:   Revision 1.84  2003/06/13 21:44:43  brouard
                    863:   * imach.c (Repository): Replace "freqsummary" at a correct
                    864:   place. It differs from routine "prevalence" which may be called
                    865:   many times. Probs is memory consuming and must be used with
                    866:   parcimony.
                    867:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    868: 
                    869:   Revision 1.83  2003/06/10 13:39:11  lievre
                    870:   *** empty log message ***
                    871: 
                    872:   Revision 1.82  2003/06/05 15:57:20  brouard
                    873:   Add log in  imach.c and  fullversion number is now printed.
                    874: 
                    875: */
                    876: /*
                    877:    Interpolated Markov Chain
                    878: 
                    879:   Short summary of the programme:
                    880:   
1.227     brouard   881:   This program computes Healthy Life Expectancies or State-specific
                    882:   (if states aren't health statuses) Expectancies from
                    883:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    884: 
                    885:   -1- a first survey ("cross") where individuals from different ages
                    886:   are interviewed on their health status or degree of disability (in
                    887:   the case of a health survey which is our main interest)
                    888: 
                    889:   -2- at least a second wave of interviews ("longitudinal") which
                    890:   measure each change (if any) in individual health status.  Health
                    891:   expectancies are computed from the time spent in each health state
                    892:   according to a model. More health states you consider, more time is
                    893:   necessary to reach the Maximum Likelihood of the parameters involved
                    894:   in the model.  The simplest model is the multinomial logistic model
                    895:   where pij is the probability to be observed in state j at the second
                    896:   wave conditional to be observed in state i at the first
                    897:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    898:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    899:   have a more complex model than "constant and age", you should modify
                    900:   the program where the markup *Covariates have to be included here
                    901:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   902:   convergence.
                    903: 
                    904:   The advantage of this computer programme, compared to a simple
                    905:   multinomial logistic model, is clear when the delay between waves is not
                    906:   identical for each individual. Also, if a individual missed an
                    907:   intermediate interview, the information is lost, but taken into
                    908:   account using an interpolation or extrapolation.  
                    909: 
                    910:   hPijx is the probability to be observed in state i at age x+h
                    911:   conditional to the observed state i at age x. The delay 'h' can be
                    912:   split into an exact number (nh*stepm) of unobserved intermediate
                    913:   states. This elementary transition (by month, quarter,
                    914:   semester or year) is modelled as a multinomial logistic.  The hPx
                    915:   matrix is simply the matrix product of nh*stepm elementary matrices
                    916:   and the contribution of each individual to the likelihood is simply
                    917:   hPijx.
                    918: 
                    919:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   920:   of the life expectancies. It also computes the period (stable) prevalence.
                    921: 
                    922: Back prevalence and projections:
1.227     brouard   923: 
                    924:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    925:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    926:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    927:    mobilavproj)
                    928: 
                    929:     Computes the back prevalence limit for any combination of
                    930:     covariate values k at any age between ageminpar and agemaxpar and
                    931:     returns it in **bprlim. In the loops,
                    932: 
                    933:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    934:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    935: 
                    936:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   937:    Computes for any combination of covariates k and any age between bage and fage 
                    938:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    939:                        oldm=oldms;savm=savms;
1.227     brouard   940: 
1.267     brouard   941:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   942:      Computes the transition matrix starting at age 'age' over
                    943:      'nhstepm*hstepm*stepm' months (i.e. until
                    944:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   945:      nhstepm*hstepm matrices. 
                    946: 
                    947:      Returns p3mat[i][j][h] after calling
                    948:      p3mat[i][j][h]=matprod2(newm,
                    949:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    950:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    951:      oldm);
1.226     brouard   952: 
                    953: Important routines
                    954: 
                    955: - func (or funcone), computes logit (pij) distinguishing
                    956:   o fixed variables (single or product dummies or quantitative);
                    957:   o varying variables by:
                    958:    (1) wave (single, product dummies, quantitative), 
                    959:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    960:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    961:        % varying dummy (not done) or quantitative (not done);
                    962: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    963:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    964: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    965:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    966:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   967: 
1.226     brouard   968: 
                    969:   
1.133     brouard   970:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    971:            Institut national d'études démographiques, Paris.
1.126     brouard   972:   This software have been partly granted by Euro-REVES, a concerted action
                    973:   from the European Union.
                    974:   It is copyrighted identically to a GNU software product, ie programme and
                    975:   software can be distributed freely for non commercial use. Latest version
                    976:   can be accessed at http://euroreves.ined.fr/imach .
                    977: 
                    978:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    979:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    980:   
                    981:   **********************************************************************/
                    982: /*
                    983:   main
                    984:   read parameterfile
                    985:   read datafile
                    986:   concatwav
                    987:   freqsummary
                    988:   if (mle >= 1)
                    989:     mlikeli
                    990:   print results files
                    991:   if mle==1 
                    992:      computes hessian
                    993:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    994:       begin-prev-date,...
                    995:   open gnuplot file
                    996:   open html file
1.145     brouard   997:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    998:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    999:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1000:     freexexit2 possible for memory heap.
                   1001: 
                   1002:   h Pij x                         | pij_nom  ficrestpij
                   1003:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1004:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1005:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1006: 
                   1007:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1008:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1009:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1010:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1011:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1012: 
1.126     brouard  1013:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1014:   health expectancies
                   1015:   Variance-covariance of DFLE
                   1016:   prevalence()
                   1017:    movingaverage()
                   1018:   varevsij() 
                   1019:   if popbased==1 varevsij(,popbased)
                   1020:   total life expectancies
                   1021:   Variance of period (stable) prevalence
                   1022:  end
                   1023: */
                   1024: 
1.187     brouard  1025: /* #define DEBUG */
                   1026: /* #define DEBUGBRENT */
1.203     brouard  1027: /* #define DEBUGLINMIN */
                   1028: /* #define DEBUGHESS */
                   1029: #define DEBUGHESSIJ
1.224     brouard  1030: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1031: #define POWELL /* Instead of NLOPT */
1.224     brouard  1032: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1033: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1034: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard  1035: 
                   1036: #include <math.h>
                   1037: #include <stdio.h>
                   1038: #include <stdlib.h>
                   1039: #include <string.h>
1.226     brouard  1040: #include <ctype.h>
1.159     brouard  1041: 
                   1042: #ifdef _WIN32
                   1043: #include <io.h>
1.172     brouard  1044: #include <windows.h>
                   1045: #include <tchar.h>
1.159     brouard  1046: #else
1.126     brouard  1047: #include <unistd.h>
1.159     brouard  1048: #endif
1.126     brouard  1049: 
                   1050: #include <limits.h>
                   1051: #include <sys/types.h>
1.171     brouard  1052: 
                   1053: #if defined(__GNUC__)
                   1054: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1055: #endif
                   1056: 
1.126     brouard  1057: #include <sys/stat.h>
                   1058: #include <errno.h>
1.159     brouard  1059: /* extern int errno; */
1.126     brouard  1060: 
1.157     brouard  1061: /* #ifdef LINUX */
                   1062: /* #include <time.h> */
                   1063: /* #include "timeval.h" */
                   1064: /* #else */
                   1065: /* #include <sys/time.h> */
                   1066: /* #endif */
                   1067: 
1.126     brouard  1068: #include <time.h>
                   1069: 
1.136     brouard  1070: #ifdef GSL
                   1071: #include <gsl/gsl_errno.h>
                   1072: #include <gsl/gsl_multimin.h>
                   1073: #endif
                   1074: 
1.167     brouard  1075: 
1.162     brouard  1076: #ifdef NLOPT
                   1077: #include <nlopt.h>
                   1078: typedef struct {
                   1079:   double (* function)(double [] );
                   1080: } myfunc_data ;
                   1081: #endif
                   1082: 
1.126     brouard  1083: /* #include <libintl.h> */
                   1084: /* #define _(String) gettext (String) */
                   1085: 
1.251     brouard  1086: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1087: 
                   1088: #define GNUPLOTPROGRAM "gnuplot"
                   1089: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1090: #define FILENAMELENGTH 132
                   1091: 
                   1092: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1093: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1094: 
1.144     brouard  1095: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1096: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1097: 
                   1098: #define NINTERVMAX 8
1.144     brouard  1099: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1100: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1101: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1102: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1103: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1104: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1105: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1106: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1107: /* #define AGESUP 130 */
1.288     brouard  1108: /* #define AGESUP 150 */
                   1109: #define AGESUP 200
1.268     brouard  1110: #define AGEINF 0
1.218     brouard  1111: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1112: #define AGEBASE 40
1.194     brouard  1113: #define AGEOVERFLOW 1.e20
1.164     brouard  1114: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1115: #ifdef _WIN32
                   1116: #define DIRSEPARATOR '\\'
                   1117: #define CHARSEPARATOR "\\"
                   1118: #define ODIRSEPARATOR '/'
                   1119: #else
1.126     brouard  1120: #define DIRSEPARATOR '/'
                   1121: #define CHARSEPARATOR "/"
                   1122: #define ODIRSEPARATOR '\\'
                   1123: #endif
                   1124: 
1.302   ! brouard  1125: /* $Id: imach.c,v 1.301 2019/06/04 13:51:20 brouard Exp $ */
1.126     brouard  1126: /* $State: Exp $ */
1.196     brouard  1127: #include "version.h"
                   1128: char version[]=__IMACH_VERSION__;
1.300     brouard  1129: char copyright[]="May 2019,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020";
1.302   ! brouard  1130: char fullversion[]="$Revision: 1.301 $ $Date: 2019/06/04 13:51:20 $"; 
1.126     brouard  1131: char strstart[80];
                   1132: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1133: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1134: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1135: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1136: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1137: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1138: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1139: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1140: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1141: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1142: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1143: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1144: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1145: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1146: int nsd=0; /**< Total number of single dummy variables (output) */
                   1147: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1148: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1149: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1150: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1151: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1152: int cptcov=0; /* Working variable */
1.290     brouard  1153: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1154: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302   ! brouard  1155: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1156: int nlstate=2; /* Number of live states */
                   1157: int ndeath=1; /* Number of dead states */
1.130     brouard  1158: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1159: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1160: int popbased=0;
                   1161: 
                   1162: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1163: int maxwav=0; /* Maxim number of waves */
                   1164: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1165: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1166: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1167:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1168: int mle=1, weightopt=0;
1.126     brouard  1169: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1170: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1171: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1172:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1173: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1174: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1175: 
1.130     brouard  1176: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1177: double **matprod2(); /* test */
1.126     brouard  1178: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1179: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1180: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1181: 
1.136     brouard  1182: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1183: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1184: FILE *ficlog, *ficrespow;
1.130     brouard  1185: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1186: double fretone; /* Only one call to likelihood */
1.130     brouard  1187: long ipmx=0; /* Number of contributions */
1.126     brouard  1188: double sw; /* Sum of weights */
                   1189: char filerespow[FILENAMELENGTH];
                   1190: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1191: FILE *ficresilk;
                   1192: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1193: FILE *ficresprobmorprev;
                   1194: FILE *fichtm, *fichtmcov; /* Html File */
                   1195: FILE *ficreseij;
                   1196: char filerese[FILENAMELENGTH];
                   1197: FILE *ficresstdeij;
                   1198: char fileresstde[FILENAMELENGTH];
                   1199: FILE *ficrescveij;
                   1200: char filerescve[FILENAMELENGTH];
                   1201: FILE  *ficresvij;
                   1202: char fileresv[FILENAMELENGTH];
1.269     brouard  1203: 
1.126     brouard  1204: char title[MAXLINE];
1.234     brouard  1205: char model[MAXLINE]; /**< The model line */
1.217     brouard  1206: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1207: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1208: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1209: char command[FILENAMELENGTH];
                   1210: int  outcmd=0;
                   1211: 
1.217     brouard  1212: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1213: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1214: char filelog[FILENAMELENGTH]; /* Log file */
                   1215: char filerest[FILENAMELENGTH];
                   1216: char fileregp[FILENAMELENGTH];
                   1217: char popfile[FILENAMELENGTH];
                   1218: 
                   1219: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1220: 
1.157     brouard  1221: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1222: /* struct timezone tzp; */
                   1223: /* extern int gettimeofday(); */
                   1224: struct tm tml, *gmtime(), *localtime();
                   1225: 
                   1226: extern time_t time();
                   1227: 
                   1228: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1229: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1230: struct tm tm;
                   1231: 
1.126     brouard  1232: char strcurr[80], strfor[80];
                   1233: 
                   1234: char *endptr;
                   1235: long lval;
                   1236: double dval;
                   1237: 
                   1238: #define NR_END 1
                   1239: #define FREE_ARG char*
                   1240: #define FTOL 1.0e-10
                   1241: 
                   1242: #define NRANSI 
1.240     brouard  1243: #define ITMAX 200
                   1244: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1245: 
                   1246: #define TOL 2.0e-4 
                   1247: 
                   1248: #define CGOLD 0.3819660 
                   1249: #define ZEPS 1.0e-10 
                   1250: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1251: 
                   1252: #define GOLD 1.618034 
                   1253: #define GLIMIT 100.0 
                   1254: #define TINY 1.0e-20 
                   1255: 
                   1256: static double maxarg1,maxarg2;
                   1257: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1258: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1259:   
                   1260: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1261: #define rint(a) floor(a+0.5)
1.166     brouard  1262: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1263: #define mytinydouble 1.0e-16
1.166     brouard  1264: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1265: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1266: /* static double dsqrarg; */
                   1267: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1268: static double sqrarg;
                   1269: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1270: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1271: int agegomp= AGEGOMP;
                   1272: 
                   1273: int imx; 
                   1274: int stepm=1;
                   1275: /* Stepm, step in month: minimum step interpolation*/
                   1276: 
                   1277: int estepm;
                   1278: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1279: 
                   1280: int m,nb;
                   1281: long *num;
1.197     brouard  1282: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1283: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1284:                   covariate for which somebody answered excluding 
                   1285:                   undefined. Usually 2: 0 and 1. */
                   1286: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1287:                             covariate for which somebody answered including 
                   1288:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1289: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1290: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1291: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1292: double *ageexmed,*agecens;
                   1293: double dateintmean=0;
1.296     brouard  1294:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1295:   double anprojf, mprojf, jprojf;
1.126     brouard  1296: 
1.296     brouard  1297:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1298:   double anbackf, mbackf, jbackf;
                   1299:   double jintmean,mintmean,aintmean;  
1.126     brouard  1300: double *weight;
                   1301: int **s; /* Status */
1.141     brouard  1302: double *agedc;
1.145     brouard  1303: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1304:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1305:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1306: double **coqvar; /* Fixed quantitative covariate nqv */
                   1307: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1308: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1309: double  idx; 
                   1310: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1311: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1312: /*k          1  2   3   4     5    6    7     8    9 */
                   1313: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1314: /* Tndvar[k]    1   2   3               4          5 */
                   1315: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1316: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1317: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1318: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1319: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1320: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1321: /* Tprod[i]=k           4               7            */
                   1322: /* Tage[i]=k                  5               8      */
                   1323: /* */
                   1324: /* Type                    */
                   1325: /* V         1  2  3  4  5 */
                   1326: /*           F  F  V  V  V */
                   1327: /*           D  Q  D  D  Q */
                   1328: /*                         */
                   1329: int *TvarsD;
                   1330: int *TvarsDind;
                   1331: int *TvarsQ;
                   1332: int *TvarsQind;
                   1333: 
1.235     brouard  1334: #define MAXRESULTLINES 10
                   1335: int nresult=0;
1.258     brouard  1336: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1337: int TKresult[MAXRESULTLINES];
1.237     brouard  1338: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1339: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1340: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1341: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1342: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1343: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1344: 
1.234     brouard  1345: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1346: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1347: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1348: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1349: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1350: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1351: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1352: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1353: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1354: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1355: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1356: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1357: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1358: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1359: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1360: 
1.230     brouard  1361: int *Tvarsel; /**< Selected covariates for output */
                   1362: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1363: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1364: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1365: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1366: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1367: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1368: int *Tage;
1.227     brouard  1369: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1370: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1371: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1372: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1373: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1374: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1375: int **Tvard;
                   1376: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1377: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1378: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1379:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1380:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1381: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1382: double *lsurv, *lpop, *tpop;
                   1383: 
1.231     brouard  1384: #define FD 1; /* Fixed dummy covariate */
                   1385: #define FQ 2; /* Fixed quantitative covariate */
                   1386: #define FP 3; /* Fixed product covariate */
                   1387: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1388: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1389: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1390: #define VD 10; /* Varying dummy covariate */
                   1391: #define VQ 11; /* Varying quantitative covariate */
                   1392: #define VP 12; /* Varying product covariate */
                   1393: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1394: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1395: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1396: #define APFD 16; /* Age product * fixed dummy covariate */
                   1397: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1398: #define APVD 18; /* Age product * varying dummy covariate */
                   1399: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1400: 
                   1401: #define FTYPE 1; /* Fixed covariate */
                   1402: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1403: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1404: 
                   1405: struct kmodel{
                   1406:        int maintype; /* main type */
                   1407:        int subtype; /* subtype */
                   1408: };
                   1409: struct kmodel modell[NCOVMAX];
                   1410: 
1.143     brouard  1411: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1412: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1413: 
                   1414: /**************** split *************************/
                   1415: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1416: {
                   1417:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1418:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1419:   */ 
                   1420:   char *ss;                            /* pointer */
1.186     brouard  1421:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1422: 
                   1423:   l1 = strlen(path );                  /* length of path */
                   1424:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1425:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1426:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1427:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1428:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1429:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1430:     /* get current working directory */
                   1431:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1432: #ifdef WIN32
                   1433:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1434: #else
                   1435:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1436: #endif
1.126     brouard  1437:       return( GLOCK_ERROR_GETCWD );
                   1438:     }
                   1439:     /* got dirc from getcwd*/
                   1440:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1441:   } else {                             /* strip directory from path */
1.126     brouard  1442:     ss++;                              /* after this, the filename */
                   1443:     l2 = strlen( ss );                 /* length of filename */
                   1444:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1445:     strcpy( name, ss );                /* save file name */
                   1446:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1447:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1448:     printf(" DIRC2 = %s \n",dirc);
                   1449:   }
                   1450:   /* We add a separator at the end of dirc if not exists */
                   1451:   l1 = strlen( dirc );                 /* length of directory */
                   1452:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1453:     dirc[l1] =  DIRSEPARATOR;
                   1454:     dirc[l1+1] = 0; 
                   1455:     printf(" DIRC3 = %s \n",dirc);
                   1456:   }
                   1457:   ss = strrchr( name, '.' );           /* find last / */
                   1458:   if (ss >0){
                   1459:     ss++;
                   1460:     strcpy(ext,ss);                    /* save extension */
                   1461:     l1= strlen( name);
                   1462:     l2= strlen(ss)+1;
                   1463:     strncpy( finame, name, l1-l2);
                   1464:     finame[l1-l2]= 0;
                   1465:   }
                   1466: 
                   1467:   return( 0 );                         /* we're done */
                   1468: }
                   1469: 
                   1470: 
                   1471: /******************************************/
                   1472: 
                   1473: void replace_back_to_slash(char *s, char*t)
                   1474: {
                   1475:   int i;
                   1476:   int lg=0;
                   1477:   i=0;
                   1478:   lg=strlen(t);
                   1479:   for(i=0; i<= lg; i++) {
                   1480:     (s[i] = t[i]);
                   1481:     if (t[i]== '\\') s[i]='/';
                   1482:   }
                   1483: }
                   1484: 
1.132     brouard  1485: char *trimbb(char *out, char *in)
1.137     brouard  1486: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1487:   char *s;
                   1488:   s=out;
                   1489:   while (*in != '\0'){
1.137     brouard  1490:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1491:       in++;
                   1492:     }
                   1493:     *out++ = *in++;
                   1494:   }
                   1495:   *out='\0';
                   1496:   return s;
                   1497: }
                   1498: 
1.187     brouard  1499: /* char *substrchaine(char *out, char *in, char *chain) */
                   1500: /* { */
                   1501: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1502: /*   char *s, *t; */
                   1503: /*   t=in;s=out; */
                   1504: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1505: /*     *out++ = *in++; */
                   1506: /*   } */
                   1507: 
                   1508: /*   /\* *in matches *chain *\/ */
                   1509: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1510: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1511: /*   } */
                   1512: /*   in--; chain--; */
                   1513: /*   while ( (*in != '\0')){ */
                   1514: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1515: /*     *out++ = *in++; */
                   1516: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1517: /*   } */
                   1518: /*   *out='\0'; */
                   1519: /*   out=s; */
                   1520: /*   return out; */
                   1521: /* } */
                   1522: char *substrchaine(char *out, char *in, char *chain)
                   1523: {
                   1524:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1525:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1526: 
                   1527:   char *strloc;
                   1528: 
                   1529:   strcpy (out, in); 
                   1530:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1531:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1532:   if(strloc != NULL){ 
                   1533:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1534:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1535:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1536:   }
                   1537:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1538:   return out;
                   1539: }
                   1540: 
                   1541: 
1.145     brouard  1542: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1543: {
1.187     brouard  1544:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1545:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1546:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1547:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1548:   */
1.160     brouard  1549:   char *s, *t;
1.145     brouard  1550:   t=in;s=in;
                   1551:   while ((*in != occ) && (*in != '\0')){
                   1552:     *alocc++ = *in++;
                   1553:   }
                   1554:   if( *in == occ){
                   1555:     *(alocc)='\0';
                   1556:     s=++in;
                   1557:   }
                   1558:  
                   1559:   if (s == t) {/* occ not found */
                   1560:     *(alocc-(in-s))='\0';
                   1561:     in=s;
                   1562:   }
                   1563:   while ( *in != '\0'){
                   1564:     *blocc++ = *in++;
                   1565:   }
                   1566: 
                   1567:   *blocc='\0';
                   1568:   return t;
                   1569: }
1.137     brouard  1570: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1571: {
1.187     brouard  1572:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1573:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1574:      gives blocc="abcdef2ghi" and alocc="j".
                   1575:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1576:   */
                   1577:   char *s, *t;
                   1578:   t=in;s=in;
                   1579:   while (*in != '\0'){
                   1580:     while( *in == occ){
                   1581:       *blocc++ = *in++;
                   1582:       s=in;
                   1583:     }
                   1584:     *blocc++ = *in++;
                   1585:   }
                   1586:   if (s == t) /* occ not found */
                   1587:     *(blocc-(in-s))='\0';
                   1588:   else
                   1589:     *(blocc-(in-s)-1)='\0';
                   1590:   in=s;
                   1591:   while ( *in != '\0'){
                   1592:     *alocc++ = *in++;
                   1593:   }
                   1594: 
                   1595:   *alocc='\0';
                   1596:   return s;
                   1597: }
                   1598: 
1.126     brouard  1599: int nbocc(char *s, char occ)
                   1600: {
                   1601:   int i,j=0;
                   1602:   int lg=20;
                   1603:   i=0;
                   1604:   lg=strlen(s);
                   1605:   for(i=0; i<= lg; i++) {
1.234     brouard  1606:     if  (s[i] == occ ) j++;
1.126     brouard  1607:   }
                   1608:   return j;
                   1609: }
                   1610: 
1.137     brouard  1611: /* void cutv(char *u,char *v, char*t, char occ) */
                   1612: /* { */
                   1613: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1614: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1615: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1616: /*   int i,lg,j,p=0; */
                   1617: /*   i=0; */
                   1618: /*   lg=strlen(t); */
                   1619: /*   for(j=0; j<=lg-1; j++) { */
                   1620: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1621: /*   } */
1.126     brouard  1622: 
1.137     brouard  1623: /*   for(j=0; j<p; j++) { */
                   1624: /*     (u[j] = t[j]); */
                   1625: /*   } */
                   1626: /*      u[p]='\0'; */
1.126     brouard  1627: 
1.137     brouard  1628: /*    for(j=0; j<= lg; j++) { */
                   1629: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1630: /*   } */
                   1631: /* } */
1.126     brouard  1632: 
1.160     brouard  1633: #ifdef _WIN32
                   1634: char * strsep(char **pp, const char *delim)
                   1635: {
                   1636:   char *p, *q;
                   1637:          
                   1638:   if ((p = *pp) == NULL)
                   1639:     return 0;
                   1640:   if ((q = strpbrk (p, delim)) != NULL)
                   1641:   {
                   1642:     *pp = q + 1;
                   1643:     *q = '\0';
                   1644:   }
                   1645:   else
                   1646:     *pp = 0;
                   1647:   return p;
                   1648: }
                   1649: #endif
                   1650: 
1.126     brouard  1651: /********************** nrerror ********************/
                   1652: 
                   1653: void nrerror(char error_text[])
                   1654: {
                   1655:   fprintf(stderr,"ERREUR ...\n");
                   1656:   fprintf(stderr,"%s\n",error_text);
                   1657:   exit(EXIT_FAILURE);
                   1658: }
                   1659: /*********************** vector *******************/
                   1660: double *vector(int nl, int nh)
                   1661: {
                   1662:   double *v;
                   1663:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1664:   if (!v) nrerror("allocation failure in vector");
                   1665:   return v-nl+NR_END;
                   1666: }
                   1667: 
                   1668: /************************ free vector ******************/
                   1669: void free_vector(double*v, int nl, int nh)
                   1670: {
                   1671:   free((FREE_ARG)(v+nl-NR_END));
                   1672: }
                   1673: 
                   1674: /************************ivector *******************************/
                   1675: int *ivector(long nl,long nh)
                   1676: {
                   1677:   int *v;
                   1678:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1679:   if (!v) nrerror("allocation failure in ivector");
                   1680:   return v-nl+NR_END;
                   1681: }
                   1682: 
                   1683: /******************free ivector **************************/
                   1684: void free_ivector(int *v, long nl, long nh)
                   1685: {
                   1686:   free((FREE_ARG)(v+nl-NR_END));
                   1687: }
                   1688: 
                   1689: /************************lvector *******************************/
                   1690: long *lvector(long nl,long nh)
                   1691: {
                   1692:   long *v;
                   1693:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1694:   if (!v) nrerror("allocation failure in ivector");
                   1695:   return v-nl+NR_END;
                   1696: }
                   1697: 
                   1698: /******************free lvector **************************/
                   1699: void free_lvector(long *v, long nl, long nh)
                   1700: {
                   1701:   free((FREE_ARG)(v+nl-NR_END));
                   1702: }
                   1703: 
                   1704: /******************* imatrix *******************************/
                   1705: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1706:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1707: { 
                   1708:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1709:   int **m; 
                   1710:   
                   1711:   /* allocate pointers to rows */ 
                   1712:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1713:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1714:   m += NR_END; 
                   1715:   m -= nrl; 
                   1716:   
                   1717:   
                   1718:   /* allocate rows and set pointers to them */ 
                   1719:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1720:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1721:   m[nrl] += NR_END; 
                   1722:   m[nrl] -= ncl; 
                   1723:   
                   1724:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1725:   
                   1726:   /* return pointer to array of pointers to rows */ 
                   1727:   return m; 
                   1728: } 
                   1729: 
                   1730: /****************** free_imatrix *************************/
                   1731: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1732:       int **m;
                   1733:       long nch,ncl,nrh,nrl; 
                   1734:      /* free an int matrix allocated by imatrix() */ 
                   1735: { 
                   1736:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1737:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1738: } 
                   1739: 
                   1740: /******************* matrix *******************************/
                   1741: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1742: {
                   1743:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1744:   double **m;
                   1745: 
                   1746:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1747:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1748:   m += NR_END;
                   1749:   m -= nrl;
                   1750: 
                   1751:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1752:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1753:   m[nrl] += NR_END;
                   1754:   m[nrl] -= ncl;
                   1755: 
                   1756:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1757:   return m;
1.145     brouard  1758:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1759: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1760: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1761:    */
                   1762: }
                   1763: 
                   1764: /*************************free matrix ************************/
                   1765: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1766: {
                   1767:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1768:   free((FREE_ARG)(m+nrl-NR_END));
                   1769: }
                   1770: 
                   1771: /******************* ma3x *******************************/
                   1772: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1773: {
                   1774:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1775:   double ***m;
                   1776: 
                   1777:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1778:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1779:   m += NR_END;
                   1780:   m -= nrl;
                   1781: 
                   1782:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1783:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1784:   m[nrl] += NR_END;
                   1785:   m[nrl] -= ncl;
                   1786: 
                   1787:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1788: 
                   1789:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1790:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1791:   m[nrl][ncl] += NR_END;
                   1792:   m[nrl][ncl] -= nll;
                   1793:   for (j=ncl+1; j<=nch; j++) 
                   1794:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1795:   
                   1796:   for (i=nrl+1; i<=nrh; i++) {
                   1797:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1798:     for (j=ncl+1; j<=nch; j++) 
                   1799:       m[i][j]=m[i][j-1]+nlay;
                   1800:   }
                   1801:   return m; 
                   1802:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1803:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1804:   */
                   1805: }
                   1806: 
                   1807: /*************************free ma3x ************************/
                   1808: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1809: {
                   1810:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1811:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1812:   free((FREE_ARG)(m+nrl-NR_END));
                   1813: }
                   1814: 
                   1815: /*************** function subdirf ***********/
                   1816: char *subdirf(char fileres[])
                   1817: {
                   1818:   /* Caution optionfilefiname is hidden */
                   1819:   strcpy(tmpout,optionfilefiname);
                   1820:   strcat(tmpout,"/"); /* Add to the right */
                   1821:   strcat(tmpout,fileres);
                   1822:   return tmpout;
                   1823: }
                   1824: 
                   1825: /*************** function subdirf2 ***********/
                   1826: char *subdirf2(char fileres[], char *preop)
                   1827: {
                   1828:   
                   1829:   /* Caution optionfilefiname is hidden */
                   1830:   strcpy(tmpout,optionfilefiname);
                   1831:   strcat(tmpout,"/");
                   1832:   strcat(tmpout,preop);
                   1833:   strcat(tmpout,fileres);
                   1834:   return tmpout;
                   1835: }
                   1836: 
                   1837: /*************** function subdirf3 ***********/
                   1838: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1839: {
                   1840:   
                   1841:   /* Caution optionfilefiname is hidden */
                   1842:   strcpy(tmpout,optionfilefiname);
                   1843:   strcat(tmpout,"/");
                   1844:   strcat(tmpout,preop);
                   1845:   strcat(tmpout,preop2);
                   1846:   strcat(tmpout,fileres);
                   1847:   return tmpout;
                   1848: }
1.213     brouard  1849:  
                   1850: /*************** function subdirfext ***********/
                   1851: char *subdirfext(char fileres[], char *preop, char *postop)
                   1852: {
                   1853:   
                   1854:   strcpy(tmpout,preop);
                   1855:   strcat(tmpout,fileres);
                   1856:   strcat(tmpout,postop);
                   1857:   return tmpout;
                   1858: }
1.126     brouard  1859: 
1.213     brouard  1860: /*************** function subdirfext3 ***********/
                   1861: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1862: {
                   1863:   
                   1864:   /* Caution optionfilefiname is hidden */
                   1865:   strcpy(tmpout,optionfilefiname);
                   1866:   strcat(tmpout,"/");
                   1867:   strcat(tmpout,preop);
                   1868:   strcat(tmpout,fileres);
                   1869:   strcat(tmpout,postop);
                   1870:   return tmpout;
                   1871: }
                   1872:  
1.162     brouard  1873: char *asc_diff_time(long time_sec, char ascdiff[])
                   1874: {
                   1875:   long sec_left, days, hours, minutes;
                   1876:   days = (time_sec) / (60*60*24);
                   1877:   sec_left = (time_sec) % (60*60*24);
                   1878:   hours = (sec_left) / (60*60) ;
                   1879:   sec_left = (sec_left) %(60*60);
                   1880:   minutes = (sec_left) /60;
                   1881:   sec_left = (sec_left) % (60);
                   1882:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1883:   return ascdiff;
                   1884: }
                   1885: 
1.126     brouard  1886: /***************** f1dim *************************/
                   1887: extern int ncom; 
                   1888: extern double *pcom,*xicom;
                   1889: extern double (*nrfunc)(double []); 
                   1890:  
                   1891: double f1dim(double x) 
                   1892: { 
                   1893:   int j; 
                   1894:   double f;
                   1895:   double *xt; 
                   1896:  
                   1897:   xt=vector(1,ncom); 
                   1898:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1899:   f=(*nrfunc)(xt); 
                   1900:   free_vector(xt,1,ncom); 
                   1901:   return f; 
                   1902: } 
                   1903: 
                   1904: /*****************brent *************************/
                   1905: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1906: {
                   1907:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1908:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1909:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1910:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1911:    * returned function value. 
                   1912:   */
1.126     brouard  1913:   int iter; 
                   1914:   double a,b,d,etemp;
1.159     brouard  1915:   double fu=0,fv,fw,fx;
1.164     brouard  1916:   double ftemp=0.;
1.126     brouard  1917:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1918:   double e=0.0; 
                   1919:  
                   1920:   a=(ax < cx ? ax : cx); 
                   1921:   b=(ax > cx ? ax : cx); 
                   1922:   x=w=v=bx; 
                   1923:   fw=fv=fx=(*f)(x); 
                   1924:   for (iter=1;iter<=ITMAX;iter++) { 
                   1925:     xm=0.5*(a+b); 
                   1926:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1927:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1928:     printf(".");fflush(stdout);
                   1929:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1930: #ifdef DEBUGBRENT
1.126     brouard  1931:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1932:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1933:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1934: #endif
                   1935:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1936:       *xmin=x; 
                   1937:       return fx; 
                   1938:     } 
                   1939:     ftemp=fu;
                   1940:     if (fabs(e) > tol1) { 
                   1941:       r=(x-w)*(fx-fv); 
                   1942:       q=(x-v)*(fx-fw); 
                   1943:       p=(x-v)*q-(x-w)*r; 
                   1944:       q=2.0*(q-r); 
                   1945:       if (q > 0.0) p = -p; 
                   1946:       q=fabs(q); 
                   1947:       etemp=e; 
                   1948:       e=d; 
                   1949:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1950:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1951:       else { 
1.224     brouard  1952:                                d=p/q; 
                   1953:                                u=x+d; 
                   1954:                                if (u-a < tol2 || b-u < tol2) 
                   1955:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1956:       } 
                   1957:     } else { 
                   1958:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1959:     } 
                   1960:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1961:     fu=(*f)(u); 
                   1962:     if (fu <= fx) { 
                   1963:       if (u >= x) a=x; else b=x; 
                   1964:       SHFT(v,w,x,u) 
1.183     brouard  1965:       SHFT(fv,fw,fx,fu) 
                   1966:     } else { 
                   1967:       if (u < x) a=u; else b=u; 
                   1968:       if (fu <= fw || w == x) { 
1.224     brouard  1969:                                v=w; 
                   1970:                                w=u; 
                   1971:                                fv=fw; 
                   1972:                                fw=fu; 
1.183     brouard  1973:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1974:                                v=u; 
                   1975:                                fv=fu; 
1.183     brouard  1976:       } 
                   1977:     } 
1.126     brouard  1978:   } 
                   1979:   nrerror("Too many iterations in brent"); 
                   1980:   *xmin=x; 
                   1981:   return fx; 
                   1982: } 
                   1983: 
                   1984: /****************** mnbrak ***********************/
                   1985: 
                   1986: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1987:            double (*func)(double)) 
1.183     brouard  1988: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1989: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1990: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1991: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1992:    */
1.126     brouard  1993:   double ulim,u,r,q, dum;
                   1994:   double fu; 
1.187     brouard  1995: 
                   1996:   double scale=10.;
                   1997:   int iterscale=0;
                   1998: 
                   1999:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2000:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2001: 
                   2002: 
                   2003:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2004:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2005:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2006:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2007:   /* } */
                   2008: 
1.126     brouard  2009:   if (*fb > *fa) { 
                   2010:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2011:     SHFT(dum,*fb,*fa,dum) 
                   2012:   } 
1.126     brouard  2013:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2014:   *fc=(*func)(*cx); 
1.183     brouard  2015: #ifdef DEBUG
1.224     brouard  2016:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2017:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2018: #endif
1.224     brouard  2019:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2020:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2021:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2022:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2023:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2024:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2025:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2026:       fu=(*func)(u); 
1.163     brouard  2027: #ifdef DEBUG
                   2028:       /* f(x)=A(x-u)**2+f(u) */
                   2029:       double A, fparabu; 
                   2030:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2031:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2032:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2033:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2034:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2035:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2036:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2037:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2038: #endif 
1.184     brouard  2039: #ifdef MNBRAKORIGINAL
1.183     brouard  2040: #else
1.191     brouard  2041: /*       if (fu > *fc) { */
                   2042: /* #ifdef DEBUG */
                   2043: /*       printf("mnbrak4  fu > fc \n"); */
                   2044: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2045: /* #endif */
                   2046: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2047: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2048: /*     dum=u; /\* Shifting c and u *\/ */
                   2049: /*     u = *cx; */
                   2050: /*     *cx = dum; */
                   2051: /*     dum = fu; */
                   2052: /*     fu = *fc; */
                   2053: /*     *fc =dum; */
                   2054: /*       } else { /\* end *\/ */
                   2055: /* #ifdef DEBUG */
                   2056: /*       printf("mnbrak3  fu < fc \n"); */
                   2057: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2058: /* #endif */
                   2059: /*     dum=u; /\* Shifting c and u *\/ */
                   2060: /*     u = *cx; */
                   2061: /*     *cx = dum; */
                   2062: /*     dum = fu; */
                   2063: /*     fu = *fc; */
                   2064: /*     *fc =dum; */
                   2065: /*       } */
1.224     brouard  2066: #ifdef DEBUGMNBRAK
                   2067:                 double A, fparabu; 
                   2068:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2069:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2070:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2071:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2072: #endif
1.191     brouard  2073:       dum=u; /* Shifting c and u */
                   2074:       u = *cx;
                   2075:       *cx = dum;
                   2076:       dum = fu;
                   2077:       fu = *fc;
                   2078:       *fc =dum;
1.183     brouard  2079: #endif
1.162     brouard  2080:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2081: #ifdef DEBUG
1.224     brouard  2082:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2083:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2084: #endif
1.126     brouard  2085:       fu=(*func)(u); 
                   2086:       if (fu < *fc) { 
1.183     brouard  2087: #ifdef DEBUG
1.224     brouard  2088:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2089:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2090: #endif
                   2091:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2092:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2093: #ifdef DEBUG
                   2094:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2095: #endif
                   2096:       } 
1.162     brouard  2097:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2098: #ifdef DEBUG
1.224     brouard  2099:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2100:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2101: #endif
1.126     brouard  2102:       u=ulim; 
                   2103:       fu=(*func)(u); 
1.183     brouard  2104:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2105: #ifdef DEBUG
1.224     brouard  2106:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2107:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2108: #endif
1.126     brouard  2109:       u=(*cx)+GOLD*(*cx-*bx); 
                   2110:       fu=(*func)(u); 
1.224     brouard  2111: #ifdef DEBUG
                   2112:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2113:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2114: #endif
1.183     brouard  2115:     } /* end tests */
1.126     brouard  2116:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2117:     SHFT(*fa,*fb,*fc,fu) 
                   2118: #ifdef DEBUG
1.224     brouard  2119:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2120:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2121: #endif
                   2122:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2123: } 
                   2124: 
                   2125: /*************** linmin ************************/
1.162     brouard  2126: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2127: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2128: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2129: the value of func at the returned location p . This is actually all accomplished by calling the
                   2130: routines mnbrak and brent .*/
1.126     brouard  2131: int ncom; 
                   2132: double *pcom,*xicom;
                   2133: double (*nrfunc)(double []); 
                   2134:  
1.224     brouard  2135: #ifdef LINMINORIGINAL
1.126     brouard  2136: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2137: #else
                   2138: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2139: #endif
1.126     brouard  2140: { 
                   2141:   double brent(double ax, double bx, double cx, 
                   2142:               double (*f)(double), double tol, double *xmin); 
                   2143:   double f1dim(double x); 
                   2144:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2145:              double *fc, double (*func)(double)); 
                   2146:   int j; 
                   2147:   double xx,xmin,bx,ax; 
                   2148:   double fx,fb,fa;
1.187     brouard  2149: 
1.203     brouard  2150: #ifdef LINMINORIGINAL
                   2151: #else
                   2152:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2153: #endif
                   2154:   
1.126     brouard  2155:   ncom=n; 
                   2156:   pcom=vector(1,n); 
                   2157:   xicom=vector(1,n); 
                   2158:   nrfunc=func; 
                   2159:   for (j=1;j<=n;j++) { 
                   2160:     pcom[j]=p[j]; 
1.202     brouard  2161:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2162:   } 
1.187     brouard  2163: 
1.203     brouard  2164: #ifdef LINMINORIGINAL
                   2165:   xx=1.;
                   2166: #else
                   2167:   axs=0.0;
                   2168:   xxs=1.;
                   2169:   do{
                   2170:     xx= xxs;
                   2171: #endif
1.187     brouard  2172:     ax=0.;
                   2173:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2174:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2175:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2176:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2177:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2178:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2179:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2180: #ifdef LINMINORIGINAL
                   2181: #else
                   2182:     if (fx != fx){
1.224     brouard  2183:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2184:                        printf("|");
                   2185:                        fprintf(ficlog,"|");
1.203     brouard  2186: #ifdef DEBUGLINMIN
1.224     brouard  2187:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2188: #endif
                   2189:     }
1.224     brouard  2190:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2191: #endif
                   2192:   
1.191     brouard  2193: #ifdef DEBUGLINMIN
                   2194:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2195:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2196: #endif
1.224     brouard  2197: #ifdef LINMINORIGINAL
                   2198: #else
                   2199:        if(fb == fx){ /* Flat function in the direction */
                   2200:                xmin=xx;
                   2201:     *flat=1;
                   2202:        }else{
                   2203:     *flat=0;
                   2204: #endif
                   2205:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2206:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2207:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2208:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2209:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2210:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2211: #ifdef DEBUG
1.224     brouard  2212:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2213:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2214: #endif
                   2215: #ifdef LINMINORIGINAL
                   2216: #else
                   2217:                        }
1.126     brouard  2218: #endif
1.191     brouard  2219: #ifdef DEBUGLINMIN
                   2220:   printf("linmin end ");
1.202     brouard  2221:   fprintf(ficlog,"linmin end ");
1.191     brouard  2222: #endif
1.126     brouard  2223:   for (j=1;j<=n;j++) { 
1.203     brouard  2224: #ifdef LINMINORIGINAL
                   2225:     xi[j] *= xmin; 
                   2226: #else
                   2227: #ifdef DEBUGLINMIN
                   2228:     if(xxs <1.0)
                   2229:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2230: #endif
                   2231:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2232: #ifdef DEBUGLINMIN
                   2233:     if(xxs <1.0)
                   2234:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2235: #endif
                   2236: #endif
1.187     brouard  2237:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2238:   } 
1.191     brouard  2239: #ifdef DEBUGLINMIN
1.203     brouard  2240:   printf("\n");
1.191     brouard  2241:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2242:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2243:   for (j=1;j<=n;j++) { 
1.202     brouard  2244:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2245:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2246:     if(j % ncovmodel == 0){
1.191     brouard  2247:       printf("\n");
1.202     brouard  2248:       fprintf(ficlog,"\n");
                   2249:     }
1.191     brouard  2250:   }
1.203     brouard  2251: #else
1.191     brouard  2252: #endif
1.126     brouard  2253:   free_vector(xicom,1,n); 
                   2254:   free_vector(pcom,1,n); 
                   2255: } 
                   2256: 
                   2257: 
                   2258: /*************** powell ************************/
1.162     brouard  2259: /*
                   2260: Minimization of a function func of n variables. Input consists of an initial starting point
                   2261: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2262: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2263: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2264: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2265: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2266:  */
1.224     brouard  2267: #ifdef LINMINORIGINAL
                   2268: #else
                   2269:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2270:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2271: #endif
1.126     brouard  2272: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2273:            double (*func)(double [])) 
                   2274: { 
1.224     brouard  2275: #ifdef LINMINORIGINAL
                   2276:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2277:              double (*func)(double [])); 
1.224     brouard  2278: #else 
1.241     brouard  2279:  void linmin(double p[], double xi[], int n, double *fret,
                   2280:             double (*func)(double []),int *flat); 
1.224     brouard  2281: #endif
1.239     brouard  2282:  int i,ibig,j,jk,k; 
1.126     brouard  2283:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2284:   double directest;
1.126     brouard  2285:   double fp,fptt;
                   2286:   double *xits;
                   2287:   int niterf, itmp;
1.224     brouard  2288: #ifdef LINMINORIGINAL
                   2289: #else
                   2290: 
                   2291:   flatdir=ivector(1,n); 
                   2292:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2293: #endif
1.126     brouard  2294: 
                   2295:   pt=vector(1,n); 
                   2296:   ptt=vector(1,n); 
                   2297:   xit=vector(1,n); 
                   2298:   xits=vector(1,n); 
                   2299:   *fret=(*func)(p); 
                   2300:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2301:   rcurr_time = time(NULL);  
1.126     brouard  2302:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2303:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2304:     ibig=0; 
                   2305:     del=0.0; 
1.157     brouard  2306:     rlast_time=rcurr_time;
                   2307:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2308:     rcurr_time = time(NULL);  
                   2309:     curr_time = *localtime(&rcurr_time);
                   2310:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2311:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2312: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2313:     for (i=1;i<=n;i++) {
1.126     brouard  2314:       fprintf(ficrespow," %.12lf", p[i]);
                   2315:     }
1.239     brouard  2316:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2317:     printf("\n#model=  1      +     age ");
                   2318:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2319:     if(nagesqr==1){
1.241     brouard  2320:        printf("  + age*age  ");
                   2321:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2322:     }
                   2323:     for(j=1;j <=ncovmodel-2;j++){
                   2324:       if(Typevar[j]==0) {
                   2325:        printf("  +      V%d  ",Tvar[j]);
                   2326:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2327:       }else if(Typevar[j]==1) {
                   2328:        printf("  +    V%d*age ",Tvar[j]);
                   2329:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2330:       }else if(Typevar[j]==2) {
                   2331:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2332:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2333:       }
                   2334:     }
1.126     brouard  2335:     printf("\n");
1.239     brouard  2336: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2337: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2338:     fprintf(ficlog,"\n");
1.239     brouard  2339:     for(i=1,jk=1; i <=nlstate; i++){
                   2340:       for(k=1; k <=(nlstate+ndeath); k++){
                   2341:        if (k != i) {
                   2342:          printf("%d%d ",i,k);
                   2343:          fprintf(ficlog,"%d%d ",i,k);
                   2344:          for(j=1; j <=ncovmodel; j++){
                   2345:            printf("%12.7f ",p[jk]);
                   2346:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2347:            jk++; 
                   2348:          }
                   2349:          printf("\n");
                   2350:          fprintf(ficlog,"\n");
                   2351:        }
                   2352:       }
                   2353:     }
1.241     brouard  2354:     if(*iter <=3 && *iter >1){
1.157     brouard  2355:       tml = *localtime(&rcurr_time);
                   2356:       strcpy(strcurr,asctime(&tml));
                   2357:       rforecast_time=rcurr_time; 
1.126     brouard  2358:       itmp = strlen(strcurr);
                   2359:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2360:        strcurr[itmp-1]='\0';
1.162     brouard  2361:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2362:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2363:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2364:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2365:        forecast_time = *localtime(&rforecast_time);
                   2366:        strcpy(strfor,asctime(&forecast_time));
                   2367:        itmp = strlen(strfor);
                   2368:        if(strfor[itmp-1]=='\n')
                   2369:          strfor[itmp-1]='\0';
                   2370:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2371:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2372:       }
                   2373:     }
1.187     brouard  2374:     for (i=1;i<=n;i++) { /* For each direction i */
                   2375:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2376:       fptt=(*fret); 
                   2377: #ifdef DEBUG
1.203     brouard  2378:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2379:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2380: #endif
1.203     brouard  2381:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2382:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2383: #ifdef LINMINORIGINAL
1.188     brouard  2384:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2385: #else
                   2386:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2387:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2388: #endif
                   2389:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2390:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2391:                                /* because that direction will be replaced unless the gain del is small */
                   2392:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2393:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2394:                                /* with the new direction. */
                   2395:                                del=fabs(fptt-(*fret)); 
                   2396:                                ibig=i; 
1.126     brouard  2397:       } 
                   2398: #ifdef DEBUG
                   2399:       printf("%d %.12e",i,(*fret));
                   2400:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2401:       for (j=1;j<=n;j++) {
1.224     brouard  2402:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2403:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2404:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2405:       }
                   2406:       for(j=1;j<=n;j++) {
1.225     brouard  2407:                                printf(" p(%d)=%.12e",j,p[j]);
                   2408:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2409:       }
                   2410:       printf("\n");
                   2411:       fprintf(ficlog,"\n");
                   2412: #endif
1.187     brouard  2413:     } /* end loop on each direction i */
                   2414:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2415:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2416:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2417:       for(j=1;j<=n;j++) {
1.302   ! brouard  2418:        if(flatdir[j] >0){
        !          2419:          printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
        !          2420:          fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
        !          2421:        }
        !          2422:        /* printf("\n"); */
        !          2423:        /* fprintf(ficlog,"\n"); */
        !          2424:       }
1.243     brouard  2425:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2426:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2427:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2428:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2429:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2430:       /* decreased of more than 3.84  */
                   2431:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2432:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2433:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2434:                        
1.188     brouard  2435:       /* Starting the program with initial values given by a former maximization will simply change */
                   2436:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2437:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2438:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2439: #ifdef DEBUG
                   2440:       int k[2],l;
                   2441:       k[0]=1;
                   2442:       k[1]=-1;
                   2443:       printf("Max: %.12e",(*func)(p));
                   2444:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2445:       for (j=1;j<=n;j++) {
                   2446:        printf(" %.12e",p[j]);
                   2447:        fprintf(ficlog," %.12e",p[j]);
                   2448:       }
                   2449:       printf("\n");
                   2450:       fprintf(ficlog,"\n");
                   2451:       for(l=0;l<=1;l++) {
                   2452:        for (j=1;j<=n;j++) {
                   2453:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2454:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2455:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2456:        }
                   2457:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2458:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2459:       }
                   2460: #endif
                   2461: 
1.224     brouard  2462: #ifdef LINMINORIGINAL
                   2463: #else
                   2464:       free_ivector(flatdir,1,n); 
                   2465: #endif
1.126     brouard  2466:       free_vector(xit,1,n); 
                   2467:       free_vector(xits,1,n); 
                   2468:       free_vector(ptt,1,n); 
                   2469:       free_vector(pt,1,n); 
                   2470:       return; 
1.192     brouard  2471:     } /* enough precision */ 
1.240     brouard  2472:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2473:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2474:       ptt[j]=2.0*p[j]-pt[j]; 
                   2475:       xit[j]=p[j]-pt[j]; 
                   2476:       pt[j]=p[j]; 
                   2477:     } 
1.181     brouard  2478:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2479: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2480:                if (*iter <=4) {
1.225     brouard  2481: #else
                   2482: #endif
1.224     brouard  2483: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2484: #else
1.161     brouard  2485:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2486: #endif
1.162     brouard  2487:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2488:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2489:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2490:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2491:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2492:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2493:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2494:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2495:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2496:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2497:       /* mu² and del² are equal when f3=f1 */
                   2498:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2499:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2500:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2501:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2502: #ifdef NRCORIGINAL
                   2503:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2504: #else
                   2505:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2506:       t= t- del*SQR(fp-fptt);
1.183     brouard  2507: #endif
1.202     brouard  2508:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2509: #ifdef DEBUG
1.181     brouard  2510:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2511:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2512:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2513:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2514:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2515:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2516:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2517:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2518: #endif
1.183     brouard  2519: #ifdef POWELLORIGINAL
                   2520:       if (t < 0.0) { /* Then we use it for new direction */
                   2521: #else
1.182     brouard  2522:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2523:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2524:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2525:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2526:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2527:       } 
1.181     brouard  2528:       if (directest < 0.0) { /* Then we use it for new direction */
                   2529: #endif
1.191     brouard  2530: #ifdef DEBUGLINMIN
1.234     brouard  2531:        printf("Before linmin in direction P%d-P0\n",n);
                   2532:        for (j=1;j<=n;j++) {
                   2533:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2534:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2535:          if(j % ncovmodel == 0){
                   2536:            printf("\n");
                   2537:            fprintf(ficlog,"\n");
                   2538:          }
                   2539:        }
1.224     brouard  2540: #endif
                   2541: #ifdef LINMINORIGINAL
1.234     brouard  2542:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2543: #else
1.234     brouard  2544:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2545:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2546: #endif
1.234     brouard  2547:        
1.191     brouard  2548: #ifdef DEBUGLINMIN
1.234     brouard  2549:        for (j=1;j<=n;j++) { 
                   2550:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2551:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2552:          if(j % ncovmodel == 0){
                   2553:            printf("\n");
                   2554:            fprintf(ficlog,"\n");
                   2555:          }
                   2556:        }
1.224     brouard  2557: #endif
1.234     brouard  2558:        for (j=1;j<=n;j++) { 
                   2559:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2560:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2561:        }
1.224     brouard  2562: #ifdef LINMINORIGINAL
                   2563: #else
1.234     brouard  2564:        for (j=1, flatd=0;j<=n;j++) {
                   2565:          if(flatdir[j]>0)
                   2566:            flatd++;
                   2567:        }
                   2568:        if(flatd >0){
1.255     brouard  2569:          printf("%d flat directions: ",flatd);
                   2570:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2571:          for (j=1;j<=n;j++) { 
                   2572:            if(flatdir[j]>0){
                   2573:              printf("%d ",j);
                   2574:              fprintf(ficlog,"%d ",j);
                   2575:            }
                   2576:          }
                   2577:          printf("\n");
                   2578:          fprintf(ficlog,"\n");
                   2579:        }
1.191     brouard  2580: #endif
1.234     brouard  2581:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2582:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2583:        
1.126     brouard  2584: #ifdef DEBUG
1.234     brouard  2585:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2586:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2587:        for(j=1;j<=n;j++){
                   2588:          printf(" %lf",xit[j]);
                   2589:          fprintf(ficlog," %lf",xit[j]);
                   2590:        }
                   2591:        printf("\n");
                   2592:        fprintf(ficlog,"\n");
1.126     brouard  2593: #endif
1.192     brouard  2594:       } /* end of t or directest negative */
1.224     brouard  2595: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2596: #else
1.234     brouard  2597:       } /* end if (fptt < fp)  */
1.192     brouard  2598: #endif
1.225     brouard  2599: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2600:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2601: #else
1.224     brouard  2602: #endif
1.234     brouard  2603:                } /* loop iteration */ 
1.126     brouard  2604: } 
1.234     brouard  2605:   
1.126     brouard  2606: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2607:   
1.235     brouard  2608:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2609:   {
1.279     brouard  2610:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2611:      *   (and selected quantitative values in nres)
                   2612:      *  by left multiplying the unit
                   2613:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2614:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2615:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2616:      * or prevalence in state 1, prevalence in state 2, 0
                   2617:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2618:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2619:      * Output is prlim.
                   2620:      * Initial matrix pimij 
                   2621:      */
1.206     brouard  2622:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2623:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2624:   /*  0,                   0                  , 1} */
                   2625:   /*
                   2626:    * and after some iteration: */
                   2627:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2628:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2629:   /*  0,                   0                  , 1} */
                   2630:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2631:   /* {0.51571254859325999, 0.4842874514067399, */
                   2632:   /*  0.51326036147820708, 0.48673963852179264} */
                   2633:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2634:     
1.126     brouard  2635:   int i, ii,j,k;
1.209     brouard  2636:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2637:   /* double **matprod2(); */ /* test */
1.218     brouard  2638:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2639:   double **newm;
1.209     brouard  2640:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2641:   int ncvloop=0;
1.288     brouard  2642:   int first=0;
1.169     brouard  2643:   
1.209     brouard  2644:   min=vector(1,nlstate);
                   2645:   max=vector(1,nlstate);
                   2646:   meandiff=vector(1,nlstate);
                   2647: 
1.218     brouard  2648:        /* Starting with matrix unity */
1.126     brouard  2649:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2650:     for (j=1;j<=nlstate+ndeath;j++){
                   2651:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2652:     }
1.169     brouard  2653:   
                   2654:   cov[1]=1.;
                   2655:   
                   2656:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2657:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2658:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2659:     ncvloop++;
1.126     brouard  2660:     newm=savm;
                   2661:     /* Covariates have to be included here again */
1.138     brouard  2662:     cov[2]=agefin;
1.187     brouard  2663:     if(nagesqr==1)
                   2664:       cov[3]= agefin*agefin;;
1.234     brouard  2665:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2666:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2667:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2668:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2669:     }
                   2670:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2671:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2672:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2673:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2674:     }
1.237     brouard  2675:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2676:       if(Dummy[Tvar[Tage[k]]]){
                   2677:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2678:       } else{
1.235     brouard  2679:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2680:       }
1.235     brouard  2681:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2682:     }
1.237     brouard  2683:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2684:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2685:       if(Dummy[Tvard[k][1]==0]){
                   2686:        if(Dummy[Tvard[k][2]==0]){
                   2687:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2688:        }else{
                   2689:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2690:        }
                   2691:       }else{
                   2692:        if(Dummy[Tvard[k][2]==0]){
                   2693:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2694:        }else{
                   2695:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2696:        }
                   2697:       }
1.234     brouard  2698:     }
1.138     brouard  2699:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2700:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2701:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2702:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2703:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2704:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2705:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2706:     
1.126     brouard  2707:     savm=oldm;
                   2708:     oldm=newm;
1.209     brouard  2709: 
                   2710:     for(j=1; j<=nlstate; j++){
                   2711:       max[j]=0.;
                   2712:       min[j]=1.;
                   2713:     }
                   2714:     for(i=1;i<=nlstate;i++){
                   2715:       sumnew=0;
                   2716:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2717:       for(j=1; j<=nlstate; j++){ 
                   2718:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2719:        max[j]=FMAX(max[j],prlim[i][j]);
                   2720:        min[j]=FMIN(min[j],prlim[i][j]);
                   2721:       }
                   2722:     }
                   2723: 
1.126     brouard  2724:     maxmax=0.;
1.209     brouard  2725:     for(j=1; j<=nlstate; j++){
                   2726:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2727:       maxmax=FMAX(maxmax,meandiff[j]);
                   2728:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2729:     } /* j loop */
1.203     brouard  2730:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2731:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2732:     if(maxmax < ftolpl){
1.209     brouard  2733:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2734:       free_vector(min,1,nlstate);
                   2735:       free_vector(max,1,nlstate);
                   2736:       free_vector(meandiff,1,nlstate);
1.126     brouard  2737:       return prlim;
                   2738:     }
1.288     brouard  2739:   } /* agefin loop */
1.208     brouard  2740:     /* After some age loop it doesn't converge */
1.288     brouard  2741:   if(!first){
                   2742:     first=1;
                   2743:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2744:   }
                   2745:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2746: 
1.209     brouard  2747:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2748:   free_vector(min,1,nlstate);
                   2749:   free_vector(max,1,nlstate);
                   2750:   free_vector(meandiff,1,nlstate);
1.208     brouard  2751:   
1.169     brouard  2752:   return prlim; /* should not reach here */
1.126     brouard  2753: }
                   2754: 
1.217     brouard  2755: 
                   2756:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2757: 
1.218     brouard  2758:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2759:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2760:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2761: {
1.264     brouard  2762:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2763:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2764:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2765:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2766:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2767:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2768:   /* Initial matrix pimij */
                   2769:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2770:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2771:   /*  0,                   0                  , 1} */
                   2772:   /*
                   2773:    * and after some iteration: */
                   2774:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2775:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2776:   /*  0,                   0                  , 1} */
                   2777:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2778:   /* {0.51571254859325999, 0.4842874514067399, */
                   2779:   /*  0.51326036147820708, 0.48673963852179264} */
                   2780:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2781: 
                   2782:   int i, ii,j,k;
1.247     brouard  2783:   int first=0;
1.217     brouard  2784:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2785:   /* double **matprod2(); */ /* test */
                   2786:   double **out, cov[NCOVMAX+1], **bmij();
                   2787:   double **newm;
1.218     brouard  2788:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2789:   double        **oldm, **savm;  /* for use */
                   2790: 
1.217     brouard  2791:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2792:   int ncvloop=0;
                   2793:   
                   2794:   min=vector(1,nlstate);
                   2795:   max=vector(1,nlstate);
                   2796:   meandiff=vector(1,nlstate);
                   2797: 
1.266     brouard  2798:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2799:   oldm=oldms; savm=savms;
                   2800:   
                   2801:   /* Starting with matrix unity */
                   2802:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2803:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2804:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2805:     }
                   2806:   
                   2807:   cov[1]=1.;
                   2808:   
                   2809:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2810:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2811:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2812:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2813:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2814:     ncvloop++;
1.218     brouard  2815:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2816:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2817:     /* Covariates have to be included here again */
                   2818:     cov[2]=agefin;
                   2819:     if(nagesqr==1)
                   2820:       cov[3]= agefin*agefin;;
1.242     brouard  2821:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2822:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2823:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2824:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2825:     }
                   2826:     /* for (k=1; k<=cptcovn;k++) { */
                   2827:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2828:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2829:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2830:     /* } */
                   2831:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2832:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2833:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2834:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2835:     }
                   2836:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2837:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2838:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2839:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2840:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2841:       if(Dummy[Tvar[Tage[k]]]){
                   2842:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2843:       } else{
                   2844:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2845:       }
                   2846:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2847:     }
                   2848:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2849:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2850:       if(Dummy[Tvard[k][1]==0]){
                   2851:        if(Dummy[Tvard[k][2]==0]){
                   2852:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2853:        }else{
                   2854:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2855:        }
                   2856:       }else{
                   2857:        if(Dummy[Tvard[k][2]==0]){
                   2858:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2859:        }else{
                   2860:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2861:        }
                   2862:       }
1.217     brouard  2863:     }
                   2864:     
                   2865:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2866:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2867:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2868:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2869:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2870:                /* ij should be linked to the correct index of cov */
                   2871:                /* age and covariate values ij are in 'cov', but we need to pass
                   2872:                 * ij for the observed prevalence at age and status and covariate
                   2873:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2874:                 */
                   2875:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2876:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2877:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2878:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2879:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2880:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2881:     /*         printf("%d newm= ",i); */
                   2882:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2883:     /*           printf("%f ",newm[i][j]); */
                   2884:     /*         } */
                   2885:     /*         printf("oldm * "); */
                   2886:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2887:     /*           printf("%f ",oldm[i][j]); */
                   2888:     /*         } */
1.268     brouard  2889:     /*         printf(" bmmij "); */
1.266     brouard  2890:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2891:     /*           printf("%f ",pmmij[i][j]); */
                   2892:     /*         } */
                   2893:     /*         printf("\n"); */
                   2894:     /*   } */
                   2895:     /* } */
1.217     brouard  2896:     savm=oldm;
                   2897:     oldm=newm;
1.266     brouard  2898: 
1.217     brouard  2899:     for(j=1; j<=nlstate; j++){
                   2900:       max[j]=0.;
                   2901:       min[j]=1.;
                   2902:     }
                   2903:     for(j=1; j<=nlstate; j++){ 
                   2904:       for(i=1;i<=nlstate;i++){
1.234     brouard  2905:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2906:        bprlim[i][j]= newm[i][j];
                   2907:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2908:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2909:       }
                   2910:     }
1.218     brouard  2911:                
1.217     brouard  2912:     maxmax=0.;
                   2913:     for(i=1; i<=nlstate; i++){
                   2914:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2915:       maxmax=FMAX(maxmax,meandiff[i]);
                   2916:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2917:     } /* i loop */
1.217     brouard  2918:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2919:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2920:     if(maxmax < ftolpl){
1.220     brouard  2921:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2922:       free_vector(min,1,nlstate);
                   2923:       free_vector(max,1,nlstate);
                   2924:       free_vector(meandiff,1,nlstate);
                   2925:       return bprlim;
                   2926:     }
1.288     brouard  2927:   } /* agefin loop */
1.217     brouard  2928:     /* After some age loop it doesn't converge */
1.288     brouard  2929:   if(!first){
1.247     brouard  2930:     first=1;
                   2931:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2932: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2933:   }
                   2934:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2935: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2936:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2937:   free_vector(min,1,nlstate);
                   2938:   free_vector(max,1,nlstate);
                   2939:   free_vector(meandiff,1,nlstate);
                   2940:   
                   2941:   return bprlim; /* should not reach here */
                   2942: }
                   2943: 
1.126     brouard  2944: /*************** transition probabilities ***************/ 
                   2945: 
                   2946: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2947: {
1.138     brouard  2948:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2949:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2950:      model to the ncovmodel covariates (including constant and age).
                   2951:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2952:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2953:      ncth covariate in the global vector x is given by the formula:
                   2954:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2955:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2956:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2957:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2958:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2959:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2960:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2961:   */
                   2962:   double s1, lnpijopii;
1.126     brouard  2963:   /*double t34;*/
1.164     brouard  2964:   int i,j, nc, ii, jj;
1.126     brouard  2965: 
1.223     brouard  2966:   for(i=1; i<= nlstate; i++){
                   2967:     for(j=1; j<i;j++){
                   2968:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2969:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2970:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2971:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2972:       }
                   2973:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2974:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2975:     }
                   2976:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2977:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2978:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2979:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2980:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2981:       }
                   2982:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2983:     }
                   2984:   }
1.218     brouard  2985:   
1.223     brouard  2986:   for(i=1; i<= nlstate; i++){
                   2987:     s1=0;
                   2988:     for(j=1; j<i; j++){
                   2989:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2990:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2991:     }
                   2992:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2993:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2994:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2995:     }
                   2996:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2997:     ps[i][i]=1./(s1+1.);
                   2998:     /* Computing other pijs */
                   2999:     for(j=1; j<i; j++)
                   3000:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3001:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3002:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3003:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3004:   } /* end i */
1.218     brouard  3005:   
1.223     brouard  3006:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3007:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3008:       ps[ii][jj]=0;
                   3009:       ps[ii][ii]=1;
                   3010:     }
                   3011:   }
1.294     brouard  3012: 
                   3013: 
1.223     brouard  3014:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3015:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3016:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3017:   /*   } */
                   3018:   /*   printf("\n "); */
                   3019:   /* } */
                   3020:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3021:   /*
                   3022:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3023:                goto end;*/
1.266     brouard  3024:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3025: }
                   3026: 
1.218     brouard  3027: /*************** backward transition probabilities ***************/ 
                   3028: 
                   3029:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3030: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3031:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3032: {
1.302   ! brouard  3033:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3034:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3035:    */
1.218     brouard  3036:   int i, ii, j,k;
1.222     brouard  3037:   
                   3038:   double **out, **pmij();
                   3039:   double sumnew=0.;
1.218     brouard  3040:   double agefin;
1.292     brouard  3041:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3042:   double **dnewm, **dsavm, **doldm;
                   3043:   double **bbmij;
                   3044:   
1.218     brouard  3045:   doldm=ddoldms; /* global pointers */
1.222     brouard  3046:   dnewm=ddnewms;
                   3047:   dsavm=ddsavms;
                   3048:   
                   3049:   agefin=cov[2];
1.268     brouard  3050:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3051:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3052:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3053:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3054: 
                   3055:   /* P_x */
1.266     brouard  3056:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3057:   /* outputs pmmij which is a stochastic matrix in row */
                   3058: 
                   3059:   /* Diag(w_x) */
1.292     brouard  3060:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3061:   sumnew=0.;
1.269     brouard  3062:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3063:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3064:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3065:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3066:   }
                   3067:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3068:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3069:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3070:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3071:     }
                   3072:   }else{
                   3073:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3074:       for (j=1;j<=nlstate+ndeath;j++)
                   3075:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3076:     }
                   3077:     /* if(sumnew <0.9){ */
                   3078:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3079:     /* } */
                   3080:   }
                   3081:   k3=0.0;  /* We put the last diagonal to 0 */
                   3082:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3083:       doldm[ii][ii]= k3;
                   3084:   }
                   3085:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3086:   
1.292     brouard  3087:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3088:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3089: 
1.292     brouard  3090:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3091:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3092:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3093:     sumnew=0.;
1.222     brouard  3094:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3095:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3096:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3097:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3098:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3099:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3100:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3101:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3102:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3103:        /* }else */
1.268     brouard  3104:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3105:     } /*End ii */
                   3106:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3107: 
1.292     brouard  3108:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3109:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3110:   /* end bmij */
1.266     brouard  3111:   return ps; /*pointer is unchanged */
1.218     brouard  3112: }
1.217     brouard  3113: /*************** transition probabilities ***************/ 
                   3114: 
1.218     brouard  3115: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3116: {
                   3117:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3118:      computes the probability to be observed in state j being in state i by appying the
                   3119:      model to the ncovmodel covariates (including constant and age).
                   3120:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3121:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3122:      ncth covariate in the global vector x is given by the formula:
                   3123:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3124:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3125:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3126:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3127:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3128:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3129:   */
                   3130:   double s1, lnpijopii;
                   3131:   /*double t34;*/
                   3132:   int i,j, nc, ii, jj;
                   3133: 
1.234     brouard  3134:   for(i=1; i<= nlstate; i++){
                   3135:     for(j=1; j<i;j++){
                   3136:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3137:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3138:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3139:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3140:       }
                   3141:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3142:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3143:     }
                   3144:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3145:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3146:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3147:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3148:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3149:       }
                   3150:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3151:     }
                   3152:   }
                   3153:   
                   3154:   for(i=1; i<= nlstate; i++){
                   3155:     s1=0;
                   3156:     for(j=1; j<i; j++){
                   3157:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3158:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3159:     }
                   3160:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3161:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3162:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3163:     }
                   3164:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3165:     ps[i][i]=1./(s1+1.);
                   3166:     /* Computing other pijs */
                   3167:     for(j=1; j<i; j++)
                   3168:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3169:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3170:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3171:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3172:   } /* end i */
                   3173:   
                   3174:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3175:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3176:       ps[ii][jj]=0;
                   3177:       ps[ii][ii]=1;
                   3178:     }
                   3179:   }
1.296     brouard  3180:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3181:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3182:     s1=0.;
                   3183:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3184:       s1+=ps[ii][jj];
                   3185:     }
                   3186:     for(ii=1; ii<= nlstate; ii++){
                   3187:       ps[ii][jj]=ps[ii][jj]/s1;
                   3188:     }
                   3189:   }
                   3190:   /* Transposition */
                   3191:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3192:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3193:       s1=ps[ii][jj];
                   3194:       ps[ii][jj]=ps[jj][ii];
                   3195:       ps[jj][ii]=s1;
                   3196:     }
                   3197:   }
                   3198:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3199:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3200:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3201:   /*   } */
                   3202:   /*   printf("\n "); */
                   3203:   /* } */
                   3204:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3205:   /*
                   3206:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3207:     goto end;*/
                   3208:   return ps;
1.217     brouard  3209: }
                   3210: 
                   3211: 
1.126     brouard  3212: /**************** Product of 2 matrices ******************/
                   3213: 
1.145     brouard  3214: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3215: {
                   3216:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3217:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3218:   /* in, b, out are matrice of pointers which should have been initialized 
                   3219:      before: only the contents of out is modified. The function returns
                   3220:      a pointer to pointers identical to out */
1.145     brouard  3221:   int i, j, k;
1.126     brouard  3222:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3223:     for(k=ncolol; k<=ncoloh; k++){
                   3224:       out[i][k]=0.;
                   3225:       for(j=ncl; j<=nch; j++)
                   3226:        out[i][k] +=in[i][j]*b[j][k];
                   3227:     }
1.126     brouard  3228:   return out;
                   3229: }
                   3230: 
                   3231: 
                   3232: /************* Higher Matrix Product ***************/
                   3233: 
1.235     brouard  3234: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3235: {
1.218     brouard  3236:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3237:      'nhstepm*hstepm*stepm' months (i.e. until
                   3238:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3239:      nhstepm*hstepm matrices. 
                   3240:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3241:      (typically every 2 years instead of every month which is too big 
                   3242:      for the memory).
                   3243:      Model is determined by parameters x and covariates have to be 
                   3244:      included manually here. 
                   3245: 
                   3246:      */
                   3247: 
                   3248:   int i, j, d, h, k;
1.131     brouard  3249:   double **out, cov[NCOVMAX+1];
1.126     brouard  3250:   double **newm;
1.187     brouard  3251:   double agexact;
1.214     brouard  3252:   double agebegin, ageend;
1.126     brouard  3253: 
                   3254:   /* Hstepm could be zero and should return the unit matrix */
                   3255:   for (i=1;i<=nlstate+ndeath;i++)
                   3256:     for (j=1;j<=nlstate+ndeath;j++){
                   3257:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3258:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3259:     }
                   3260:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3261:   for(h=1; h <=nhstepm; h++){
                   3262:     for(d=1; d <=hstepm; d++){
                   3263:       newm=savm;
                   3264:       /* Covariates have to be included here again */
                   3265:       cov[1]=1.;
1.214     brouard  3266:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3267:       cov[2]=agexact;
                   3268:       if(nagesqr==1)
1.227     brouard  3269:        cov[3]= agexact*agexact;
1.235     brouard  3270:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3271:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3272:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3273:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3274:       }
                   3275:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3276:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3277:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3278:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3279:       }
                   3280:       for (k=1; k<=cptcovage;k++){
                   3281:        if(Dummy[Tvar[Tage[k]]]){
                   3282:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3283:        } else{
                   3284:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3285:        }
                   3286:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3287:       }
                   3288:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3289:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3290:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3291:       }
                   3292:       /* for (k=1; k<=cptcovn;k++)  */
                   3293:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3294:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3295:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3296:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3297:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3298:       
                   3299:       
1.126     brouard  3300:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3301:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3302:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3303:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3304:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3305:       /* if((int)age == 70){ */
                   3306:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3307:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3308:       /*         printf("%d pmmij ",i); */
                   3309:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3310:       /*           printf("%f ",pmmij[i][j]); */
                   3311:       /*         } */
                   3312:       /*         printf(" oldm "); */
                   3313:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3314:       /*           printf("%f ",oldm[i][j]); */
                   3315:       /*         } */
                   3316:       /*         printf("\n"); */
                   3317:       /*       } */
                   3318:       /* } */
1.126     brouard  3319:       savm=oldm;
                   3320:       oldm=newm;
                   3321:     }
                   3322:     for(i=1; i<=nlstate+ndeath; i++)
                   3323:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3324:        po[i][j][h]=newm[i][j];
                   3325:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3326:       }
1.128     brouard  3327:     /*printf("h=%d ",h);*/
1.126     brouard  3328:   } /* end h */
1.267     brouard  3329:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3330:   return po;
                   3331: }
                   3332: 
1.217     brouard  3333: /************* Higher Back Matrix Product ***************/
1.218     brouard  3334: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3335: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3336: {
1.266     brouard  3337:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3338:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3339:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3340:      nhstepm*hstepm matrices.
                   3341:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3342:      (typically every 2 years instead of every month which is too big
1.217     brouard  3343:      for the memory).
1.218     brouard  3344:      Model is determined by parameters x and covariates have to be
1.266     brouard  3345:      included manually here. Then we use a call to bmij(x and cov)
                   3346:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3347:   */
1.217     brouard  3348: 
                   3349:   int i, j, d, h, k;
1.266     brouard  3350:   double **out, cov[NCOVMAX+1], **bmij();
                   3351:   double **newm, ***newmm;
1.217     brouard  3352:   double agexact;
                   3353:   double agebegin, ageend;
1.222     brouard  3354:   double **oldm, **savm;
1.217     brouard  3355: 
1.266     brouard  3356:   newmm=po; /* To be saved */
                   3357:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3358:   /* Hstepm could be zero and should return the unit matrix */
                   3359:   for (i=1;i<=nlstate+ndeath;i++)
                   3360:     for (j=1;j<=nlstate+ndeath;j++){
                   3361:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3362:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3363:     }
                   3364:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3365:   for(h=1; h <=nhstepm; h++){
                   3366:     for(d=1; d <=hstepm; d++){
                   3367:       newm=savm;
                   3368:       /* Covariates have to be included here again */
                   3369:       cov[1]=1.;
1.271     brouard  3370:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3371:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3372:       cov[2]=agexact;
                   3373:       if(nagesqr==1)
1.222     brouard  3374:        cov[3]= agexact*agexact;
1.266     brouard  3375:       for (k=1; k<=cptcovn;k++){
                   3376:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3377:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3378:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3379:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3380:       }
1.267     brouard  3381:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3382:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3383:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3384:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3385:       }
                   3386:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3387:        if(Dummy[Tvar[Tage[k]]]){
                   3388:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3389:        } else{
                   3390:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3391:        }
                   3392:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3393:       }
                   3394:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3395:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3396:       }                        
1.217     brouard  3397:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3398:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3399: 
1.218     brouard  3400:       /* Careful transposed matrix */
1.266     brouard  3401:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3402:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3403:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3404:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3405:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3406:       /* if((int)age == 70){ */
                   3407:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3408:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3409:       /*         printf("%d pmmij ",i); */
                   3410:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3411:       /*           printf("%f ",pmmij[i][j]); */
                   3412:       /*         } */
                   3413:       /*         printf(" oldm "); */
                   3414:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3415:       /*           printf("%f ",oldm[i][j]); */
                   3416:       /*         } */
                   3417:       /*         printf("\n"); */
                   3418:       /*       } */
                   3419:       /* } */
                   3420:       savm=oldm;
                   3421:       oldm=newm;
                   3422:     }
                   3423:     for(i=1; i<=nlstate+ndeath; i++)
                   3424:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3425:        po[i][j][h]=newm[i][j];
1.268     brouard  3426:        /* if(h==nhstepm) */
                   3427:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3428:       }
1.268     brouard  3429:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3430:   } /* end h */
1.268     brouard  3431:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3432:   return po;
                   3433: }
                   3434: 
                   3435: 
1.162     brouard  3436: #ifdef NLOPT
                   3437:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3438:   double fret;
                   3439:   double *xt;
                   3440:   int j;
                   3441:   myfunc_data *d2 = (myfunc_data *) pd;
                   3442: /* xt = (p1-1); */
                   3443:   xt=vector(1,n); 
                   3444:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3445: 
                   3446:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3447:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3448:   printf("Function = %.12lf ",fret);
                   3449:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3450:   printf("\n");
                   3451:  free_vector(xt,1,n);
                   3452:   return fret;
                   3453: }
                   3454: #endif
1.126     brouard  3455: 
                   3456: /*************** log-likelihood *************/
                   3457: double func( double *x)
                   3458: {
1.226     brouard  3459:   int i, ii, j, k, mi, d, kk;
                   3460:   int ioffset=0;
                   3461:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3462:   double **out;
                   3463:   double lli; /* Individual log likelihood */
                   3464:   int s1, s2;
1.228     brouard  3465:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3466:   double bbh, survp;
                   3467:   long ipmx;
                   3468:   double agexact;
                   3469:   /*extern weight */
                   3470:   /* We are differentiating ll according to initial status */
                   3471:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3472:   /*for(i=1;i<imx;i++) 
                   3473:     printf(" %d\n",s[4][i]);
                   3474:   */
1.162     brouard  3475: 
1.226     brouard  3476:   ++countcallfunc;
1.162     brouard  3477: 
1.226     brouard  3478:   cov[1]=1.;
1.126     brouard  3479: 
1.226     brouard  3480:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3481:   ioffset=0;
1.226     brouard  3482:   if(mle==1){
                   3483:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3484:       /* Computes the values of the ncovmodel covariates of the model
                   3485:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3486:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3487:         to be observed in j being in i according to the model.
                   3488:       */
1.243     brouard  3489:       ioffset=2+nagesqr ;
1.233     brouard  3490:    /* Fixed */
1.234     brouard  3491:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3492:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3493:       }
1.226     brouard  3494:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3495:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3496:         has been calculated etc */
                   3497:       /* For an individual i, wav[i] gives the number of effective waves */
                   3498:       /* We compute the contribution to Likelihood of each effective transition
                   3499:         mw[mi][i] is real wave of the mi th effectve wave */
                   3500:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3501:         s2=s[mw[mi+1][i]][i];
                   3502:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3503:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3504:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3505:       */
                   3506:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3507:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3508:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3509:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3510:        }
                   3511:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3512:          for (j=1;j<=nlstate+ndeath;j++){
                   3513:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3514:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3515:          }
                   3516:        for(d=0; d<dh[mi][i]; d++){
                   3517:          newm=savm;
                   3518:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3519:          cov[2]=agexact;
                   3520:          if(nagesqr==1)
                   3521:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3522:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3523:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3524:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3525:          else
                   3526:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3527:          }
                   3528:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3529:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3530:          savm=oldm;
                   3531:          oldm=newm;
                   3532:        } /* end mult */
                   3533:        
                   3534:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3535:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3536:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3537:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3538:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3539:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3540:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3541:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3542:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3543:                                 * -stepm/2 to stepm/2 .
                   3544:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3545:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3546:                                 */
1.234     brouard  3547:        s1=s[mw[mi][i]][i];
                   3548:        s2=s[mw[mi+1][i]][i];
                   3549:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3550:        /* bias bh is positive if real duration
                   3551:         * is higher than the multiple of stepm and negative otherwise.
                   3552:         */
                   3553:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3554:        if( s2 > nlstate){ 
                   3555:          /* i.e. if s2 is a death state and if the date of death is known 
                   3556:             then the contribution to the likelihood is the probability to 
                   3557:             die between last step unit time and current  step unit time, 
                   3558:             which is also equal to probability to die before dh 
                   3559:             minus probability to die before dh-stepm . 
                   3560:             In version up to 0.92 likelihood was computed
                   3561:             as if date of death was unknown. Death was treated as any other
                   3562:             health state: the date of the interview describes the actual state
                   3563:             and not the date of a change in health state. The former idea was
                   3564:             to consider that at each interview the state was recorded
                   3565:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3566:             introduced the exact date of death then we should have modified
                   3567:             the contribution of an exact death to the likelihood. This new
                   3568:             contribution is smaller and very dependent of the step unit
                   3569:             stepm. It is no more the probability to die between last interview
                   3570:             and month of death but the probability to survive from last
                   3571:             interview up to one month before death multiplied by the
                   3572:             probability to die within a month. Thanks to Chris
                   3573:             Jackson for correcting this bug.  Former versions increased
                   3574:             mortality artificially. The bad side is that we add another loop
                   3575:             which slows down the processing. The difference can be up to 10%
                   3576:             lower mortality.
                   3577:          */
                   3578:          /* If, at the beginning of the maximization mostly, the
                   3579:             cumulative probability or probability to be dead is
                   3580:             constant (ie = 1) over time d, the difference is equal to
                   3581:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3582:             s1 at precedent wave, to be dead a month before current
                   3583:             wave is equal to probability, being at state s1 at
                   3584:             precedent wave, to be dead at mont of the current
                   3585:             wave. Then the observed probability (that this person died)
                   3586:             is null according to current estimated parameter. In fact,
                   3587:             it should be very low but not zero otherwise the log go to
                   3588:             infinity.
                   3589:          */
1.183     brouard  3590: /* #ifdef INFINITYORIGINAL */
                   3591: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3592: /* #else */
                   3593: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3594: /*         lli=log(mytinydouble); */
                   3595: /*       else */
                   3596: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3597: /* #endif */
1.226     brouard  3598:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3599:          
1.226     brouard  3600:        } else if  ( s2==-1 ) { /* alive */
                   3601:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3602:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3603:          /*survp += out[s1][j]; */
                   3604:          lli= log(survp);
                   3605:        }
                   3606:        else if  (s2==-4) { 
                   3607:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3608:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3609:          lli= log(survp); 
                   3610:        } 
                   3611:        else if  (s2==-5) { 
                   3612:          for (j=1,survp=0. ; j<=2; j++)  
                   3613:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3614:          lli= log(survp); 
                   3615:        } 
                   3616:        else{
                   3617:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3618:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3619:        } 
                   3620:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3621:        /*if(lli ==000.0)*/
                   3622:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3623:        ipmx +=1;
                   3624:        sw += weight[i];
                   3625:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3626:        /* if (lli < log(mytinydouble)){ */
                   3627:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3628:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3629:        /* } */
                   3630:       } /* end of wave */
                   3631:     } /* end of individual */
                   3632:   }  else if(mle==2){
                   3633:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3634:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3635:       for(mi=1; mi<= wav[i]-1; mi++){
                   3636:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3637:          for (j=1;j<=nlstate+ndeath;j++){
                   3638:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3639:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3640:          }
                   3641:        for(d=0; d<=dh[mi][i]; d++){
                   3642:          newm=savm;
                   3643:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3644:          cov[2]=agexact;
                   3645:          if(nagesqr==1)
                   3646:            cov[3]= agexact*agexact;
                   3647:          for (kk=1; kk<=cptcovage;kk++) {
                   3648:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3649:          }
                   3650:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3651:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3652:          savm=oldm;
                   3653:          oldm=newm;
                   3654:        } /* end mult */
                   3655:       
                   3656:        s1=s[mw[mi][i]][i];
                   3657:        s2=s[mw[mi+1][i]][i];
                   3658:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3659:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3660:        ipmx +=1;
                   3661:        sw += weight[i];
                   3662:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3663:       } /* end of wave */
                   3664:     } /* end of individual */
                   3665:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3666:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3667:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3668:       for(mi=1; mi<= wav[i]-1; mi++){
                   3669:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3670:          for (j=1;j<=nlstate+ndeath;j++){
                   3671:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3672:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3673:          }
                   3674:        for(d=0; d<dh[mi][i]; d++){
                   3675:          newm=savm;
                   3676:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3677:          cov[2]=agexact;
                   3678:          if(nagesqr==1)
                   3679:            cov[3]= agexact*agexact;
                   3680:          for (kk=1; kk<=cptcovage;kk++) {
                   3681:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3682:          }
                   3683:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3684:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3685:          savm=oldm;
                   3686:          oldm=newm;
                   3687:        } /* end mult */
                   3688:       
                   3689:        s1=s[mw[mi][i]][i];
                   3690:        s2=s[mw[mi+1][i]][i];
                   3691:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3692:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3693:        ipmx +=1;
                   3694:        sw += weight[i];
                   3695:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3696:       } /* end of wave */
                   3697:     } /* end of individual */
                   3698:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3699:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3700:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3701:       for(mi=1; mi<= wav[i]-1; mi++){
                   3702:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3703:          for (j=1;j<=nlstate+ndeath;j++){
                   3704:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3705:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3706:          }
                   3707:        for(d=0; d<dh[mi][i]; d++){
                   3708:          newm=savm;
                   3709:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3710:          cov[2]=agexact;
                   3711:          if(nagesqr==1)
                   3712:            cov[3]= agexact*agexact;
                   3713:          for (kk=1; kk<=cptcovage;kk++) {
                   3714:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3715:          }
1.126     brouard  3716:        
1.226     brouard  3717:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3718:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3719:          savm=oldm;
                   3720:          oldm=newm;
                   3721:        } /* end mult */
                   3722:       
                   3723:        s1=s[mw[mi][i]][i];
                   3724:        s2=s[mw[mi+1][i]][i];
                   3725:        if( s2 > nlstate){ 
                   3726:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3727:        } else if  ( s2==-1 ) { /* alive */
                   3728:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3729:            survp += out[s1][j];
                   3730:          lli= log(survp);
                   3731:        }else{
                   3732:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3733:        }
                   3734:        ipmx +=1;
                   3735:        sw += weight[i];
                   3736:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3737: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3738:       } /* end of wave */
                   3739:     } /* end of individual */
                   3740:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3741:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3742:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3743:       for(mi=1; mi<= wav[i]-1; mi++){
                   3744:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3745:          for (j=1;j<=nlstate+ndeath;j++){
                   3746:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3747:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3748:          }
                   3749:        for(d=0; d<dh[mi][i]; d++){
                   3750:          newm=savm;
                   3751:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3752:          cov[2]=agexact;
                   3753:          if(nagesqr==1)
                   3754:            cov[3]= agexact*agexact;
                   3755:          for (kk=1; kk<=cptcovage;kk++) {
                   3756:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3757:          }
1.126     brouard  3758:        
1.226     brouard  3759:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3760:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3761:          savm=oldm;
                   3762:          oldm=newm;
                   3763:        } /* end mult */
                   3764:       
                   3765:        s1=s[mw[mi][i]][i];
                   3766:        s2=s[mw[mi+1][i]][i];
                   3767:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3768:        ipmx +=1;
                   3769:        sw += weight[i];
                   3770:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3771:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3772:       } /* end of wave */
                   3773:     } /* end of individual */
                   3774:   } /* End of if */
                   3775:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3776:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3777:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3778:   return -l;
1.126     brouard  3779: }
                   3780: 
                   3781: /*************** log-likelihood *************/
                   3782: double funcone( double *x)
                   3783: {
1.228     brouard  3784:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3785:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3786:   int ioffset=0;
1.131     brouard  3787:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3788:   double **out;
                   3789:   double lli; /* Individual log likelihood */
                   3790:   double llt;
                   3791:   int s1, s2;
1.228     brouard  3792:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3793: 
1.126     brouard  3794:   double bbh, survp;
1.187     brouard  3795:   double agexact;
1.214     brouard  3796:   double agebegin, ageend;
1.126     brouard  3797:   /*extern weight */
                   3798:   /* We are differentiating ll according to initial status */
                   3799:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3800:   /*for(i=1;i<imx;i++) 
                   3801:     printf(" %d\n",s[4][i]);
                   3802:   */
                   3803:   cov[1]=1.;
                   3804: 
                   3805:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3806:   ioffset=0;
                   3807:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3808:     /* ioffset=2+nagesqr+cptcovage; */
                   3809:     ioffset=2+nagesqr;
1.232     brouard  3810:     /* Fixed */
1.224     brouard  3811:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3812:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3813:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3814:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3815: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3816: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3817: /*    cov[2+6]=covar[2][i]; V2  */
                   3818: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3819: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3820: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3821: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3822: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3823: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3824:     }
1.232     brouard  3825:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3826:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3827:     /* } */
1.231     brouard  3828:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3829:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3830:     /* } */
1.225     brouard  3831:     
1.233     brouard  3832: 
                   3833:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3834:     /* Wave varying (but not age varying) */
                   3835:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3836:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3837:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3838:       }
1.232     brouard  3839:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3840:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3841:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3842:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3843:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3844:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3845:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3846:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3847:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3848:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3849:       /* } */
1.126     brouard  3850:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3851:        for (j=1;j<=nlstate+ndeath;j++){
                   3852:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3853:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3854:        }
1.214     brouard  3855:       
                   3856:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3857:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3858:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3859:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3860:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3861:          and mw[mi+1][i]. dh depends on stepm.*/
                   3862:        newm=savm;
1.247     brouard  3863:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3864:        cov[2]=agexact;
                   3865:        if(nagesqr==1)
                   3866:          cov[3]= agexact*agexact;
                   3867:        for (kk=1; kk<=cptcovage;kk++) {
                   3868:          if(!FixedV[Tvar[Tage[kk]]])
                   3869:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3870:          else
                   3871:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3872:        }
                   3873:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3874:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3875:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3876:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3877:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3878:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3879:        savm=oldm;
                   3880:        oldm=newm;
1.126     brouard  3881:       } /* end mult */
                   3882:       
                   3883:       s1=s[mw[mi][i]][i];
                   3884:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3885:       /* if(s2==-1){ */
1.268     brouard  3886:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3887:       /*       /\* exit(1); *\/ */
                   3888:       /* } */
1.126     brouard  3889:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3890:       /* bias is positive if real duration
                   3891:        * is higher than the multiple of stepm and negative otherwise.
                   3892:        */
                   3893:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3894:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3895:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3896:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3897:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3898:        lli= log(survp);
1.126     brouard  3899:       }else if (mle==1){
1.242     brouard  3900:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3901:       } else if(mle==2){
1.242     brouard  3902:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3903:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3904:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3905:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3906:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3907:       } else{  /* mle=0 back to 1 */
1.242     brouard  3908:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3909:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3910:       } /* End of if */
                   3911:       ipmx +=1;
                   3912:       sw += weight[i];
                   3913:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3914:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3915:       if(globpr){
1.246     brouard  3916:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3917:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3918:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3919:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3920:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3921:          llt +=ll[k]*gipmx/gsw;
                   3922:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3923:        }
                   3924:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3925:       }
1.232     brouard  3926:        } /* end of wave */
                   3927: } /* end of individual */
                   3928: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3929: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3930: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3931: if(globpr==0){ /* First time we count the contributions and weights */
                   3932:        gipmx=ipmx;
                   3933:        gsw=sw;
                   3934: }
                   3935: return -l;
1.126     brouard  3936: }
                   3937: 
                   3938: 
                   3939: /*************** function likelione ***********/
1.292     brouard  3940: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3941: {
                   3942:   /* This routine should help understanding what is done with 
                   3943:      the selection of individuals/waves and
                   3944:      to check the exact contribution to the likelihood.
                   3945:      Plotting could be done.
                   3946:    */
                   3947:   int k;
                   3948: 
                   3949:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3950:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3951:     strcat(fileresilk,fileresu);
1.126     brouard  3952:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3953:       printf("Problem with resultfile: %s\n", fileresilk);
                   3954:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3955:     }
1.214     brouard  3956:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3957:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3958:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3959:     for(k=1; k<=nlstate; k++) 
                   3960:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3961:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3962:   }
                   3963: 
1.292     brouard  3964:   *fretone=(*func)(p);
1.126     brouard  3965:   if(*globpri !=0){
                   3966:     fclose(ficresilk);
1.205     brouard  3967:     if (mle ==0)
                   3968:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3969:     else if(mle >=1)
                   3970:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3971:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3972:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3973:       
                   3974:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3975:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3976: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3977:     }
1.207     brouard  3978:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3979: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3980:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3981: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3982:     fflush(fichtm);
1.205     brouard  3983:   }
1.126     brouard  3984:   return;
                   3985: }
                   3986: 
                   3987: 
                   3988: /*********** Maximum Likelihood Estimation ***************/
                   3989: 
                   3990: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3991: {
1.165     brouard  3992:   int i,j, iter=0;
1.126     brouard  3993:   double **xi;
                   3994:   double fret;
                   3995:   double fretone; /* Only one call to likelihood */
                   3996:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3997: 
                   3998: #ifdef NLOPT
                   3999:   int creturn;
                   4000:   nlopt_opt opt;
                   4001:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4002:   double *lb;
                   4003:   double minf; /* the minimum objective value, upon return */
                   4004:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4005:   myfunc_data dinst, *d = &dinst;
                   4006: #endif
                   4007: 
                   4008: 
1.126     brouard  4009:   xi=matrix(1,npar,1,npar);
                   4010:   for (i=1;i<=npar;i++)
                   4011:     for (j=1;j<=npar;j++)
                   4012:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4013:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4014:   strcpy(filerespow,"POW_"); 
1.126     brouard  4015:   strcat(filerespow,fileres);
                   4016:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4017:     printf("Problem with resultfile: %s\n", filerespow);
                   4018:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4019:   }
                   4020:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4021:   for (i=1;i<=nlstate;i++)
                   4022:     for(j=1;j<=nlstate+ndeath;j++)
                   4023:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4024:   fprintf(ficrespow,"\n");
1.162     brouard  4025: #ifdef POWELL
1.126     brouard  4026:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  4027: #endif
1.126     brouard  4028: 
1.162     brouard  4029: #ifdef NLOPT
                   4030: #ifdef NEWUOA
                   4031:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4032: #else
                   4033:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4034: #endif
                   4035:   lb=vector(0,npar-1);
                   4036:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4037:   nlopt_set_lower_bounds(opt, lb);
                   4038:   nlopt_set_initial_step1(opt, 0.1);
                   4039:   
                   4040:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4041:   d->function = func;
                   4042:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4043:   nlopt_set_min_objective(opt, myfunc, d);
                   4044:   nlopt_set_xtol_rel(opt, ftol);
                   4045:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4046:     printf("nlopt failed! %d\n",creturn); 
                   4047:   }
                   4048:   else {
                   4049:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4050:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4051:     iter=1; /* not equal */
                   4052:   }
                   4053:   nlopt_destroy(opt);
                   4054: #endif
1.126     brouard  4055:   free_matrix(xi,1,npar,1,npar);
                   4056:   fclose(ficrespow);
1.203     brouard  4057:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4058:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4059:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4060: 
                   4061: }
                   4062: 
                   4063: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4064: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4065: {
                   4066:   double  **a,**y,*x,pd;
1.203     brouard  4067:   /* double **hess; */
1.164     brouard  4068:   int i, j;
1.126     brouard  4069:   int *indx;
                   4070: 
                   4071:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4072:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4073:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4074:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4075:   double gompertz(double p[]);
1.203     brouard  4076:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4077: 
                   4078:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4079:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4080:   for (i=1;i<=npar;i++){
1.203     brouard  4081:     printf("%d-",i);fflush(stdout);
                   4082:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4083:    
                   4084:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4085:     
                   4086:     /*  printf(" %f ",p[i]);
                   4087:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4088:   }
                   4089:   
                   4090:   for (i=1;i<=npar;i++) {
                   4091:     for (j=1;j<=npar;j++)  {
                   4092:       if (j>i) { 
1.203     brouard  4093:        printf(".%d-%d",i,j);fflush(stdout);
                   4094:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4095:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4096:        
                   4097:        hess[j][i]=hess[i][j];    
                   4098:        /*printf(" %lf ",hess[i][j]);*/
                   4099:       }
                   4100:     }
                   4101:   }
                   4102:   printf("\n");
                   4103:   fprintf(ficlog,"\n");
                   4104: 
                   4105:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4106:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4107:   
                   4108:   a=matrix(1,npar,1,npar);
                   4109:   y=matrix(1,npar,1,npar);
                   4110:   x=vector(1,npar);
                   4111:   indx=ivector(1,npar);
                   4112:   for (i=1;i<=npar;i++)
                   4113:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4114:   ludcmp(a,npar,indx,&pd);
                   4115: 
                   4116:   for (j=1;j<=npar;j++) {
                   4117:     for (i=1;i<=npar;i++) x[i]=0;
                   4118:     x[j]=1;
                   4119:     lubksb(a,npar,indx,x);
                   4120:     for (i=1;i<=npar;i++){ 
                   4121:       matcov[i][j]=x[i];
                   4122:     }
                   4123:   }
                   4124: 
                   4125:   printf("\n#Hessian matrix#\n");
                   4126:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4127:   for (i=1;i<=npar;i++) { 
                   4128:     for (j=1;j<=npar;j++) { 
1.203     brouard  4129:       printf("%.6e ",hess[i][j]);
                   4130:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4131:     }
                   4132:     printf("\n");
                   4133:     fprintf(ficlog,"\n");
                   4134:   }
                   4135: 
1.203     brouard  4136:   /* printf("\n#Covariance matrix#\n"); */
                   4137:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4138:   /* for (i=1;i<=npar;i++) {  */
                   4139:   /*   for (j=1;j<=npar;j++) {  */
                   4140:   /*     printf("%.6e ",matcov[i][j]); */
                   4141:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4142:   /*   } */
                   4143:   /*   printf("\n"); */
                   4144:   /*   fprintf(ficlog,"\n"); */
                   4145:   /* } */
                   4146: 
1.126     brouard  4147:   /* Recompute Inverse */
1.203     brouard  4148:   /* for (i=1;i<=npar;i++) */
                   4149:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4150:   /* ludcmp(a,npar,indx,&pd); */
                   4151: 
                   4152:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4153: 
                   4154:   /* for (j=1;j<=npar;j++) { */
                   4155:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4156:   /*   x[j]=1; */
                   4157:   /*   lubksb(a,npar,indx,x); */
                   4158:   /*   for (i=1;i<=npar;i++){  */
                   4159:   /*     y[i][j]=x[i]; */
                   4160:   /*     printf("%.3e ",y[i][j]); */
                   4161:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4162:   /*   } */
                   4163:   /*   printf("\n"); */
                   4164:   /*   fprintf(ficlog,"\n"); */
                   4165:   /* } */
                   4166: 
                   4167:   /* Verifying the inverse matrix */
                   4168: #ifdef DEBUGHESS
                   4169:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4170: 
1.203     brouard  4171:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4172:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4173: 
                   4174:   for (j=1;j<=npar;j++) {
                   4175:     for (i=1;i<=npar;i++){ 
1.203     brouard  4176:       printf("%.2f ",y[i][j]);
                   4177:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4178:     }
                   4179:     printf("\n");
                   4180:     fprintf(ficlog,"\n");
                   4181:   }
1.203     brouard  4182: #endif
1.126     brouard  4183: 
                   4184:   free_matrix(a,1,npar,1,npar);
                   4185:   free_matrix(y,1,npar,1,npar);
                   4186:   free_vector(x,1,npar);
                   4187:   free_ivector(indx,1,npar);
1.203     brouard  4188:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4189: 
                   4190: 
                   4191: }
                   4192: 
                   4193: /*************** hessian matrix ****************/
                   4194: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4195: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4196:   int i;
                   4197:   int l=1, lmax=20;
1.203     brouard  4198:   double k1,k2, res, fx;
1.132     brouard  4199:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4200:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4201:   int k=0,kmax=10;
                   4202:   double l1;
                   4203: 
                   4204:   fx=func(x);
                   4205:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4206:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4207:     l1=pow(10,l);
                   4208:     delts=delt;
                   4209:     for(k=1 ; k <kmax; k=k+1){
                   4210:       delt = delta*(l1*k);
                   4211:       p2[theta]=x[theta] +delt;
1.145     brouard  4212:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4213:       p2[theta]=x[theta]-delt;
                   4214:       k2=func(p2)-fx;
                   4215:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4216:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4217:       
1.203     brouard  4218: #ifdef DEBUGHESSII
1.126     brouard  4219:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4220:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4221: #endif
                   4222:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4223:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4224:        k=kmax;
                   4225:       }
                   4226:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4227:        k=kmax; l=lmax*10;
1.126     brouard  4228:       }
                   4229:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4230:        delts=delt;
                   4231:       }
1.203     brouard  4232:     } /* End loop k */
1.126     brouard  4233:   }
                   4234:   delti[theta]=delts;
                   4235:   return res; 
                   4236:   
                   4237: }
                   4238: 
1.203     brouard  4239: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4240: {
                   4241:   int i;
1.164     brouard  4242:   int l=1, lmax=20;
1.126     brouard  4243:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4244:   double p2[MAXPARM+1];
1.203     brouard  4245:   int k, kmax=1;
                   4246:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4247: 
                   4248:   int firstime=0;
1.203     brouard  4249:   
1.126     brouard  4250:   fx=func(x);
1.203     brouard  4251:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4252:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4253:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4254:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4255:     k1=func(p2)-fx;
                   4256:   
1.203     brouard  4257:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4258:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4259:     k2=func(p2)-fx;
                   4260:   
1.203     brouard  4261:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4262:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4263:     k3=func(p2)-fx;
                   4264:   
1.203     brouard  4265:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4266:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4267:     k4=func(p2)-fx;
1.203     brouard  4268:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4269:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4270:       firstime=1;
1.203     brouard  4271:       kmax=kmax+10;
1.208     brouard  4272:     }
                   4273:     if(kmax >=10 || firstime ==1){
1.246     brouard  4274:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4275:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4276:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4277:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4278:     }
                   4279: #ifdef DEBUGHESSIJ
                   4280:     v1=hess[thetai][thetai];
                   4281:     v2=hess[thetaj][thetaj];
                   4282:     cv12=res;
                   4283:     /* Computing eigen value of Hessian matrix */
                   4284:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4285:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4286:     if ((lc2 <0) || (lc1 <0) ){
                   4287:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4288:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4289:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4290:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4291:     }
1.126     brouard  4292: #endif
                   4293:   }
                   4294:   return res;
                   4295: }
                   4296: 
1.203     brouard  4297:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4298: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4299: /* { */
                   4300: /*   int i; */
                   4301: /*   int l=1, lmax=20; */
                   4302: /*   double k1,k2,k3,k4,res,fx; */
                   4303: /*   double p2[MAXPARM+1]; */
                   4304: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4305: /*   int k=0,kmax=10; */
                   4306: /*   double l1; */
                   4307:   
                   4308: /*   fx=func(x); */
                   4309: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4310: /*     l1=pow(10,l); */
                   4311: /*     delts=delt; */
                   4312: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4313: /*       delt = delti*(l1*k); */
                   4314: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4315: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4316: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4317: /*       k1=func(p2)-fx; */
                   4318:       
                   4319: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4320: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4321: /*       k2=func(p2)-fx; */
                   4322:       
                   4323: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4324: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4325: /*       k3=func(p2)-fx; */
                   4326:       
                   4327: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4328: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4329: /*       k4=func(p2)-fx; */
                   4330: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4331: /* #ifdef DEBUGHESSIJ */
                   4332: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4333: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4334: /* #endif */
                   4335: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4336: /*     k=kmax; */
                   4337: /*       } */
                   4338: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4339: /*     k=kmax; l=lmax*10; */
                   4340: /*       } */
                   4341: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4342: /*     delts=delt; */
                   4343: /*       } */
                   4344: /*     } /\* End loop k *\/ */
                   4345: /*   } */
                   4346: /*   delti[theta]=delts; */
                   4347: /*   return res;  */
                   4348: /* } */
                   4349: 
                   4350: 
1.126     brouard  4351: /************** Inverse of matrix **************/
                   4352: void ludcmp(double **a, int n, int *indx, double *d) 
                   4353: { 
                   4354:   int i,imax,j,k; 
                   4355:   double big,dum,sum,temp; 
                   4356:   double *vv; 
                   4357:  
                   4358:   vv=vector(1,n); 
                   4359:   *d=1.0; 
                   4360:   for (i=1;i<=n;i++) { 
                   4361:     big=0.0; 
                   4362:     for (j=1;j<=n;j++) 
                   4363:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4364:     if (big == 0.0){
                   4365:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4366:       for (j=1;j<=n;j++) {
                   4367:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4368:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4369:       }
                   4370:       fflush(ficlog);
                   4371:       fclose(ficlog);
                   4372:       nrerror("Singular matrix in routine ludcmp"); 
                   4373:     }
1.126     brouard  4374:     vv[i]=1.0/big; 
                   4375:   } 
                   4376:   for (j=1;j<=n;j++) { 
                   4377:     for (i=1;i<j;i++) { 
                   4378:       sum=a[i][j]; 
                   4379:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4380:       a[i][j]=sum; 
                   4381:     } 
                   4382:     big=0.0; 
                   4383:     for (i=j;i<=n;i++) { 
                   4384:       sum=a[i][j]; 
                   4385:       for (k=1;k<j;k++) 
                   4386:        sum -= a[i][k]*a[k][j]; 
                   4387:       a[i][j]=sum; 
                   4388:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4389:        big=dum; 
                   4390:        imax=i; 
                   4391:       } 
                   4392:     } 
                   4393:     if (j != imax) { 
                   4394:       for (k=1;k<=n;k++) { 
                   4395:        dum=a[imax][k]; 
                   4396:        a[imax][k]=a[j][k]; 
                   4397:        a[j][k]=dum; 
                   4398:       } 
                   4399:       *d = -(*d); 
                   4400:       vv[imax]=vv[j]; 
                   4401:     } 
                   4402:     indx[j]=imax; 
                   4403:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4404:     if (j != n) { 
                   4405:       dum=1.0/(a[j][j]); 
                   4406:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4407:     } 
                   4408:   } 
                   4409:   free_vector(vv,1,n);  /* Doesn't work */
                   4410: ;
                   4411: } 
                   4412: 
                   4413: void lubksb(double **a, int n, int *indx, double b[]) 
                   4414: { 
                   4415:   int i,ii=0,ip,j; 
                   4416:   double sum; 
                   4417:  
                   4418:   for (i=1;i<=n;i++) { 
                   4419:     ip=indx[i]; 
                   4420:     sum=b[ip]; 
                   4421:     b[ip]=b[i]; 
                   4422:     if (ii) 
                   4423:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4424:     else if (sum) ii=i; 
                   4425:     b[i]=sum; 
                   4426:   } 
                   4427:   for (i=n;i>=1;i--) { 
                   4428:     sum=b[i]; 
                   4429:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4430:     b[i]=sum/a[i][i]; 
                   4431:   } 
                   4432: } 
                   4433: 
                   4434: void pstamp(FILE *fichier)
                   4435: {
1.196     brouard  4436:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4437: }
                   4438: 
1.297     brouard  4439: void date2dmy(double date,double *day, double *month, double *year){
                   4440:   double yp=0., yp1=0., yp2=0.;
                   4441:   
                   4442:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4443:                        fractional in yp1 */
                   4444:   *year=yp;
                   4445:   yp2=modf((yp1*12),&yp);
                   4446:   *month=yp;
                   4447:   yp1=modf((yp2*30.5),&yp);
                   4448:   *day=yp;
                   4449:   if(*day==0) *day=1;
                   4450:   if(*month==0) *month=1;
                   4451: }
                   4452: 
1.253     brouard  4453: 
                   4454: 
1.126     brouard  4455: /************ Frequencies ********************/
1.251     brouard  4456: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4457:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4458:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4459: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4460:   
1.265     brouard  4461:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4462:   int iind=0, iage=0;
                   4463:   int mi; /* Effective wave */
                   4464:   int first;
                   4465:   double ***freq; /* Frequencies */
1.268     brouard  4466:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4467:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4468:   double *meanq, *stdq, *idq;
1.226     brouard  4469:   double **meanqt;
                   4470:   double *pp, **prop, *posprop, *pospropt;
                   4471:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4472:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4473:   double agebegin, ageend;
                   4474:     
                   4475:   pp=vector(1,nlstate);
1.251     brouard  4476:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4477:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4478:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4479:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4480:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4481:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4482:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4483:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4484:   strcpy(fileresp,"P_");
                   4485:   strcat(fileresp,fileresu);
                   4486:   /*strcat(fileresphtm,fileresu);*/
                   4487:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4488:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4489:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4490:     exit(0);
                   4491:   }
1.240     brouard  4492:   
1.226     brouard  4493:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4494:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4495:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4496:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4497:     fflush(ficlog);
                   4498:     exit(70); 
                   4499:   }
                   4500:   else{
                   4501:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4502: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4503: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4504:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4505:   }
1.237     brouard  4506:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4507:   
1.226     brouard  4508:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4509:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4510:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4511:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4512:     fflush(ficlog);
                   4513:     exit(70); 
1.240     brouard  4514:   } else{
1.226     brouard  4515:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4516: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4517: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4518:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4519:   }
1.240     brouard  4520:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4521:   
1.253     brouard  4522:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4523:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4524:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4525:   j1=0;
1.126     brouard  4526:   
1.227     brouard  4527:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4528:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4529:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4530:   
                   4531:   
1.226     brouard  4532:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4533:      reference=low_education V1=0,V2=0
                   4534:      med_educ                V1=1 V2=0, 
                   4535:      high_educ               V1=0 V2=1
                   4536:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4537:   */
1.249     brouard  4538:   dateintsum=0;
                   4539:   k2cpt=0;
                   4540: 
1.253     brouard  4541:   if(cptcoveff == 0 )
1.265     brouard  4542:     nl=1;  /* Constant and age model only */
1.253     brouard  4543:   else
                   4544:     nl=2;
1.265     brouard  4545: 
                   4546:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4547:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4548:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4549:    *     freq[s1][s2][iage] =0.
                   4550:    *     Loop on iind
                   4551:    *       ++freq[s1][s2][iage] weighted
                   4552:    *     end iind
                   4553:    *     if covariate and j!0
                   4554:    *       headers Variable on one line
                   4555:    *     endif cov j!=0
                   4556:    *     header of frequency table by age
                   4557:    *     Loop on age
                   4558:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4559:    *       pos+=freq[s1][s2][iage] weighted
                   4560:    *       Loop on s1 initial state
                   4561:    *         fprintf(ficresp
                   4562:    *       end s1
                   4563:    *     end age
                   4564:    *     if j!=0 computes starting values
                   4565:    *     end compute starting values
                   4566:    *   end j1
                   4567:    * end nl 
                   4568:    */
1.253     brouard  4569:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4570:     if(nj==1)
                   4571:       j=0;  /* First pass for the constant */
1.265     brouard  4572:     else{
1.253     brouard  4573:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4574:     }
1.251     brouard  4575:     first=1;
1.265     brouard  4576:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4577:       posproptt=0.;
                   4578:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4579:        scanf("%d", i);*/
                   4580:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4581:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4582:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4583:            freq[i][s2][m]=0;
1.251     brouard  4584:       
                   4585:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4586:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4587:          prop[i][m]=0;
                   4588:        posprop[i]=0;
                   4589:        pospropt[i]=0;
                   4590:       }
1.283     brouard  4591:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4592:         idq[z1]=0.;
                   4593:         meanq[z1]=0.;
                   4594:         stdq[z1]=0.;
1.283     brouard  4595:       }
                   4596:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4597:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4598:       /*         meanqt[m][z1]=0.; */
                   4599:       /*       } */
                   4600:       /* }       */
1.251     brouard  4601:       /* dateintsum=0; */
                   4602:       /* k2cpt=0; */
                   4603:       
1.265     brouard  4604:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4605:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4606:        bool=1;
                   4607:        if(j !=0){
                   4608:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4609:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4610:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4611:                /* if(Tvaraff[z1] ==-20){ */
                   4612:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4613:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4614:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4615:                /* }else  */
                   4616:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4617:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4618:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4619:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4620:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4621:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4622:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4623:                } /* Onlyf fixed */
                   4624:              } /* end z1 */
                   4625:            } /* cptcovn > 0 */
                   4626:          } /* end any */
                   4627:        }/* end j==0 */
1.265     brouard  4628:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4629:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4630:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4631:            m=mw[mi][iind];
                   4632:            if(j!=0){
                   4633:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4634:                for (z1=1; z1<=cptcoveff; z1++) {
                   4635:                  if( Fixed[Tmodelind[z1]]==1){
                   4636:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4637:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4638:                                                                                      value is -1, we don't select. It differs from the 
                   4639:                                                                                      constant and age model which counts them. */
                   4640:                      bool=0; /* not selected */
                   4641:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4642:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4643:                      bool=0;
                   4644:                    }
                   4645:                  }
                   4646:                }
                   4647:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4648:            } /* end j==0 */
                   4649:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4650:            if(bool==1){ /*Selected */
1.251     brouard  4651:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4652:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4653:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4654:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4655:              if(m >=firstpass && m <=lastpass){
                   4656:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4657:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4658:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4659:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4660:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4661:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4662:                if (m<lastpass) {
                   4663:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4664:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4665:                  if(s[m][iind]==-1)
                   4666:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4667:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4668:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4669:                    idq[z1]=idq[z1]+weight[iind];
                   4670:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4671:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4672:                  }
1.251     brouard  4673:                  /* if((int)agev[m][iind] == 55) */
                   4674:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4675:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4676:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4677:                }
1.251     brouard  4678:              } /* end if between passes */  
                   4679:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4680:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4681:                k2cpt++;
                   4682:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4683:              }
1.251     brouard  4684:            }else{
                   4685:              bool=1;
                   4686:            }/* end bool 2 */
                   4687:          } /* end m */
1.284     brouard  4688:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4689:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4690:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4691:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4692:          /* } */
1.251     brouard  4693:        } /* end bool */
                   4694:       } /* end iind = 1 to imx */
                   4695:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4696:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4697:       
                   4698:       
                   4699:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4700:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4701:         pstamp(ficresp);
1.251     brouard  4702:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4703:         pstamp(ficresp);
1.251     brouard  4704:        printf( "\n#********** Variable "); 
                   4705:        fprintf(ficresp, "\n#********** Variable "); 
                   4706:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4707:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4708:        fprintf(ficlog, "\n#********** Variable "); 
                   4709:        for (z1=1; z1<=cptcoveff; z1++){
                   4710:          if(!FixedV[Tvaraff[z1]]){
                   4711:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4712:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4713:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4714:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4715:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4716:          }else{
1.251     brouard  4717:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4718:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4719:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4720:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4721:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4722:          }
                   4723:        }
                   4724:        printf( "**********\n#");
                   4725:        fprintf(ficresp, "**********\n#");
                   4726:        fprintf(ficresphtm, "**********</h3>\n");
                   4727:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4728:        fprintf(ficlog, "**********\n");
                   4729:       }
1.284     brouard  4730:       /*
                   4731:        Printing means of quantitative variables if any
                   4732:       */
                   4733:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4734:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4735:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4736:        if(weightopt==1){
                   4737:          printf(" Weighted mean and standard deviation of");
                   4738:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4739:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4740:        }
1.285     brouard  4741:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4742:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4743:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4744:       }
                   4745:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4746:       /*       for(m=1;m<=lastpass;m++){ */
                   4747:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4748:       /*   } */
                   4749:       /* } */
1.283     brouard  4750: 
1.251     brouard  4751:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4752:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4753:         fprintf(ficresp, " Age");
                   4754:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4755:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4756:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4757:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4758:       }
1.265     brouard  4759:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4760:       fprintf(ficresphtm, "\n");
                   4761:       
                   4762:       /* Header of frequency table by age */
                   4763:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4764:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4765:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4766:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4767:          if(s2!=0 && m!=0)
                   4768:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4769:        }
1.226     brouard  4770:       }
1.251     brouard  4771:       fprintf(ficresphtmfr, "\n");
                   4772:     
                   4773:       /* For each age */
                   4774:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4775:        fprintf(ficresphtm,"<tr>");
                   4776:        if(iage==iagemax+1){
                   4777:          fprintf(ficlog,"1");
                   4778:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4779:        }else if(iage==iagemax+2){
                   4780:          fprintf(ficlog,"0");
                   4781:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4782:        }else if(iage==iagemax+3){
                   4783:          fprintf(ficlog,"Total");
                   4784:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4785:        }else{
1.240     brouard  4786:          if(first==1){
1.251     brouard  4787:            first=0;
                   4788:            printf("See log file for details...\n");
                   4789:          }
                   4790:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4791:          fprintf(ficlog,"Age %d", iage);
                   4792:        }
1.265     brouard  4793:        for(s1=1; s1 <=nlstate ; s1++){
                   4794:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4795:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4796:        }
1.265     brouard  4797:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4798:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4799:            pos += freq[s1][m][iage];
                   4800:          if(pp[s1]>=1.e-10){
1.251     brouard  4801:            if(first==1){
1.265     brouard  4802:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4803:            }
1.265     brouard  4804:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4805:          }else{
                   4806:            if(first==1)
1.265     brouard  4807:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4808:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4809:          }
                   4810:        }
                   4811:       
1.265     brouard  4812:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4813:          /* posprop[s1]=0; */
                   4814:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4815:            pp[s1] += freq[s1][m][iage];
                   4816:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4817:       
                   4818:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4819:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4820:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4821:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4822:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4823:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4824:        }
                   4825:        
                   4826:        /* Writing ficresp */
                   4827:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4828:           if( iage <= iagemax){
                   4829:            fprintf(ficresp," %d",iage);
                   4830:           }
                   4831:         }else if( nj==2){
                   4832:           if( iage <= iagemax){
                   4833:            fprintf(ficresp," %d",iage);
                   4834:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4835:           }
1.240     brouard  4836:        }
1.265     brouard  4837:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4838:          if(pos>=1.e-5){
1.251     brouard  4839:            if(first==1)
1.265     brouard  4840:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4841:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4842:          }else{
                   4843:            if(first==1)
1.265     brouard  4844:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4845:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4846:          }
                   4847:          if( iage <= iagemax){
                   4848:            if(pos>=1.e-5){
1.265     brouard  4849:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4850:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4851:               }else if( nj==2){
                   4852:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4853:               }
                   4854:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4855:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4856:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4857:            } else{
                   4858:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4859:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4860:            }
1.240     brouard  4861:          }
1.265     brouard  4862:          pospropt[s1] +=posprop[s1];
                   4863:        } /* end loop s1 */
1.251     brouard  4864:        /* pospropt=0.; */
1.265     brouard  4865:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4866:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4867:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4868:              if(first==1){
1.265     brouard  4869:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4870:              }
1.265     brouard  4871:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4872:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4873:            }
1.265     brouard  4874:            if(s1!=0 && m!=0)
                   4875:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4876:          }
1.265     brouard  4877:        } /* end loop s1 */
1.251     brouard  4878:        posproptt=0.; 
1.265     brouard  4879:        for(s1=1; s1 <=nlstate; s1++){
                   4880:          posproptt += pospropt[s1];
1.251     brouard  4881:        }
                   4882:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4883:        fprintf(ficresphtm,"</tr>\n");
                   4884:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4885:          if(iage <= iagemax)
                   4886:            fprintf(ficresp,"\n");
1.240     brouard  4887:        }
1.251     brouard  4888:        if(first==1)
                   4889:          printf("Others in log...\n");
                   4890:        fprintf(ficlog,"\n");
                   4891:       } /* end loop age iage */
1.265     brouard  4892:       
1.251     brouard  4893:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4894:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4895:        if(posproptt < 1.e-5){
1.265     brouard  4896:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4897:        }else{
1.265     brouard  4898:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4899:        }
1.226     brouard  4900:       }
1.251     brouard  4901:       fprintf(ficresphtm,"</tr>\n");
                   4902:       fprintf(ficresphtm,"</table>\n");
                   4903:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4904:       if(posproptt < 1.e-5){
1.251     brouard  4905:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4906:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4907:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4908:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4909:        invalidvarcomb[j1]=1;
1.226     brouard  4910:       }else{
1.251     brouard  4911:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4912:        invalidvarcomb[j1]=0;
1.226     brouard  4913:       }
1.251     brouard  4914:       fprintf(ficresphtmfr,"</table>\n");
                   4915:       fprintf(ficlog,"\n");
                   4916:       if(j!=0){
                   4917:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4918:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4919:          for(k=1; k <=(nlstate+ndeath); k++){
                   4920:            if (k != i) {
1.265     brouard  4921:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4922:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4923:                  if(j1==1){ /* All dummy covariates to zero */
                   4924:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4925:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4926:                    printf("%d%d ",i,k);
                   4927:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4928:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4929:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4930:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4931:                  }
1.253     brouard  4932:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4933:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4934:                    x[iage]= (double)iage;
                   4935:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4936:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4937:                  }
1.268     brouard  4938:                  /* Some are not finite, but linreg will ignore these ages */
                   4939:                  no=0;
1.253     brouard  4940:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4941:                  pstart[s1]=b;
                   4942:                  pstart[s1-1]=a;
1.252     brouard  4943:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4944:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4945:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4946:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4947:                  printf("%d%d ",i,k);
                   4948:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4949:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4950:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4951:                  ;
                   4952:                }
                   4953:                /* printf("%12.7f )", param[i][jj][k]); */
                   4954:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4955:                s1++; 
1.251     brouard  4956:              } /* end jj */
                   4957:            } /* end k!= i */
                   4958:          } /* end k */
1.265     brouard  4959:        } /* end i, s1 */
1.251     brouard  4960:       } /* end j !=0 */
                   4961:     } /* end selected combination of covariate j1 */
                   4962:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4963:       printf("#Freqsummary: Starting values for the constants:\n");
                   4964:       fprintf(ficlog,"\n");
1.265     brouard  4965:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4966:        for(k=1; k <=(nlstate+ndeath); k++){
                   4967:          if (k != i) {
                   4968:            printf("%d%d ",i,k);
                   4969:            fprintf(ficlog,"%d%d ",i,k);
                   4970:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4971:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4972:              if(jj==1){ /* Age has to be done */
1.265     brouard  4973:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4974:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4975:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4976:              }
                   4977:              /* printf("%12.7f )", param[i][jj][k]); */
                   4978:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4979:              s1++; 
1.250     brouard  4980:            }
1.251     brouard  4981:            printf("\n");
                   4982:            fprintf(ficlog,"\n");
1.250     brouard  4983:          }
                   4984:        }
1.284     brouard  4985:       } /* end of state i */
1.251     brouard  4986:       printf("#Freqsummary\n");
                   4987:       fprintf(ficlog,"\n");
1.265     brouard  4988:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4989:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4990:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4991:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4992:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4993:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4994:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4995:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4996:          /* } */
                   4997:        }
1.265     brouard  4998:       } /* end loop s1 */
1.251     brouard  4999:       
                   5000:       printf("\n");
                   5001:       fprintf(ficlog,"\n");
                   5002:     } /* end j=0 */
1.249     brouard  5003:   } /* end j */
1.252     brouard  5004: 
1.253     brouard  5005:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5006:     for(i=1, jk=1; i <=nlstate; i++){
                   5007:       for(j=1; j <=nlstate+ndeath; j++){
                   5008:        if(j!=i){
                   5009:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5010:          printf("%1d%1d",i,j);
                   5011:          fprintf(ficparo,"%1d%1d",i,j);
                   5012:          for(k=1; k<=ncovmodel;k++){
                   5013:            /*    printf(" %lf",param[i][j][k]); */
                   5014:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5015:            p[jk]=pstart[jk];
                   5016:            printf(" %f ",pstart[jk]);
                   5017:            fprintf(ficparo," %f ",pstart[jk]);
                   5018:            jk++;
                   5019:          }
                   5020:          printf("\n");
                   5021:          fprintf(ficparo,"\n");
                   5022:        }
                   5023:       }
                   5024:     }
                   5025:   } /* end mle=-2 */
1.226     brouard  5026:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5027:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5028:   
1.226     brouard  5029:   fclose(ficresp);
                   5030:   fclose(ficresphtm);
                   5031:   fclose(ficresphtmfr);
1.283     brouard  5032:   free_vector(idq,1,nqfveff);
1.226     brouard  5033:   free_vector(meanq,1,nqfveff);
1.284     brouard  5034:   free_vector(stdq,1,nqfveff);
1.226     brouard  5035:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5036:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5037:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5038:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5039:   free_vector(pospropt,1,nlstate);
                   5040:   free_vector(posprop,1,nlstate);
1.251     brouard  5041:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5042:   free_vector(pp,1,nlstate);
                   5043:   /* End of freqsummary */
                   5044: }
1.126     brouard  5045: 
1.268     brouard  5046: /* Simple linear regression */
                   5047: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5048: 
                   5049:   /* y=a+bx regression */
                   5050:   double   sumx = 0.0;                        /* sum of x                      */
                   5051:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5052:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5053:   double   sumy = 0.0;                        /* sum of y                      */
                   5054:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5055:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5056:   double yhat;
                   5057:   
                   5058:   double denom=0;
                   5059:   int i;
                   5060:   int ne=*no;
                   5061:   
                   5062:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5063:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5064:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5065:       continue;
                   5066:     }
                   5067:     ne=ne+1;
                   5068:     sumx  += x[i];       
                   5069:     sumx2 += x[i]*x[i];  
                   5070:     sumxy += x[i] * y[i];
                   5071:     sumy  += y[i];      
                   5072:     sumy2 += y[i]*y[i]; 
                   5073:     denom = (ne * sumx2 - sumx*sumx);
                   5074:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5075:   } 
                   5076:   
                   5077:   denom = (ne * sumx2 - sumx*sumx);
                   5078:   if (denom == 0) {
                   5079:     // vertical, slope m is infinity
                   5080:     *b = INFINITY;
                   5081:     *a = 0;
                   5082:     if (r) *r = 0;
                   5083:     return 1;
                   5084:   }
                   5085:   
                   5086:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5087:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5088:   if (r!=NULL) {
                   5089:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5090:       sqrt((sumx2 - sumx*sumx/ne) *
                   5091:           (sumy2 - sumy*sumy/ne));
                   5092:   }
                   5093:   *no=ne;
                   5094:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5095:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5096:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5097:       continue;
                   5098:     }
                   5099:     ne=ne+1;
                   5100:     yhat = y[i] - *a -*b* x[i];
                   5101:     sume2  += yhat * yhat ;       
                   5102:     
                   5103:     denom = (ne * sumx2 - sumx*sumx);
                   5104:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5105:   } 
                   5106:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5107:   *sa= *sb * sqrt(sumx2/ne);
                   5108:   
                   5109:   return 0; 
                   5110: }
                   5111: 
1.126     brouard  5112: /************ Prevalence ********************/
1.227     brouard  5113: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5114: {  
                   5115:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5116:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5117:      We still use firstpass and lastpass as another selection.
                   5118:   */
1.126     brouard  5119:  
1.227     brouard  5120:   int i, m, jk, j1, bool, z1,j, iv;
                   5121:   int mi; /* Effective wave */
                   5122:   int iage;
                   5123:   double agebegin, ageend;
                   5124: 
                   5125:   double **prop;
                   5126:   double posprop; 
                   5127:   double  y2; /* in fractional years */
                   5128:   int iagemin, iagemax;
                   5129:   int first; /** to stop verbosity which is redirected to log file */
                   5130: 
                   5131:   iagemin= (int) agemin;
                   5132:   iagemax= (int) agemax;
                   5133:   /*pp=vector(1,nlstate);*/
1.251     brouard  5134:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5135:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5136:   j1=0;
1.222     brouard  5137:   
1.227     brouard  5138:   /*j=cptcoveff;*/
                   5139:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5140:   
1.288     brouard  5141:   first=0;
1.227     brouard  5142:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5143:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5144:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5145:        prop[i][iage]=0.0;
                   5146:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5147:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5148:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5149:     
                   5150:     for (i=1; i<=imx; i++) { /* Each individual */
                   5151:       bool=1;
                   5152:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5153:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5154:        m=mw[mi][i];
                   5155:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5156:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5157:        for (z1=1; z1<=cptcoveff; z1++){
                   5158:          if( Fixed[Tmodelind[z1]]==1){
                   5159:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5160:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5161:              bool=0;
                   5162:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5163:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5164:              bool=0;
                   5165:            }
                   5166:        }
                   5167:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5168:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5169:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5170:          if(m >=firstpass && m <=lastpass){
                   5171:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5172:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5173:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5174:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5175:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5176:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5177:                exit(1);
                   5178:              }
                   5179:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5180:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5181:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5182:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5183:              } /* end valid statuses */ 
                   5184:            } /* end selection of dates */
                   5185:          } /* end selection of waves */
                   5186:        } /* end bool */
                   5187:       } /* end wave */
                   5188:     } /* end individual */
                   5189:     for(i=iagemin; i <= iagemax+3; i++){  
                   5190:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5191:        posprop += prop[jk][i]; 
                   5192:       } 
                   5193:       
                   5194:       for(jk=1; jk <=nlstate ; jk++){      
                   5195:        if( i <=  iagemax){ 
                   5196:          if(posprop>=1.e-5){ 
                   5197:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5198:          } else{
1.288     brouard  5199:            if(!first){
                   5200:              first=1;
1.266     brouard  5201:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5202:            }else{
1.288     brouard  5203:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5204:            }
                   5205:          }
                   5206:        } 
                   5207:       }/* end jk */ 
                   5208:     }/* end i */ 
1.222     brouard  5209:      /*} *//* end i1 */
1.227     brouard  5210:   } /* end j1 */
1.222     brouard  5211:   
1.227     brouard  5212:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5213:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5214:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5215: }  /* End of prevalence */
1.126     brouard  5216: 
                   5217: /************* Waves Concatenation ***************/
                   5218: 
                   5219: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5220: {
1.298     brouard  5221:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5222:      Death is a valid wave (if date is known).
                   5223:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5224:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5225:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5226:   */
1.126     brouard  5227: 
1.224     brouard  5228:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5229:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5230:      double sum=0., jmean=0.;*/
1.224     brouard  5231:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5232:   int j, k=0,jk, ju, jl;
                   5233:   double sum=0.;
                   5234:   first=0;
1.214     brouard  5235:   firstwo=0;
1.217     brouard  5236:   firsthree=0;
1.218     brouard  5237:   firstfour=0;
1.164     brouard  5238:   jmin=100000;
1.126     brouard  5239:   jmax=-1;
                   5240:   jmean=0.;
1.224     brouard  5241: 
                   5242: /* Treating live states */
1.214     brouard  5243:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5244:     mi=0;  /* First valid wave */
1.227     brouard  5245:     mli=0; /* Last valid wave */
1.126     brouard  5246:     m=firstpass;
1.214     brouard  5247:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5248:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5249:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5250:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5251:        mw[++mi][i]=m;
                   5252:        mli=m;
1.224     brouard  5253:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5254:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5255:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5256:       }
1.227     brouard  5257:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5258: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5259:        break;
1.224     brouard  5260: #else
1.227     brouard  5261:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5262:          if(firsthree == 0){
1.302   ! brouard  5263:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5264:            firsthree=1;
                   5265:          }
1.302   ! brouard  5266:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5267:          mw[++mi][i]=m;
                   5268:          mli=m;
                   5269:        }
                   5270:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5271:          nbwarn++;
                   5272:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5273:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5274:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5275:          }
                   5276:          break;
                   5277:        }
                   5278:        break;
1.224     brouard  5279: #endif
1.227     brouard  5280:       }/* End m >= lastpass */
1.126     brouard  5281:     }/* end while */
1.224     brouard  5282: 
1.227     brouard  5283:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5284:     /* After last pass */
1.224     brouard  5285: /* Treating death states */
1.214     brouard  5286:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5287:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5288:       /* } */
1.126     brouard  5289:       mi++;    /* Death is another wave */
                   5290:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5291:       /* Only death is a correct wave */
1.126     brouard  5292:       mw[mi][i]=m;
1.257     brouard  5293:     } /* else not in a death state */
1.224     brouard  5294: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5295:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5296:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5297:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5298:          nbwarn++;
                   5299:          if(firstfiv==0){
                   5300:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5301:            firstfiv=1;
                   5302:          }else{
                   5303:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5304:          }
                   5305:        }else{ /* Death occured afer last wave potential bias */
                   5306:          nberr++;
                   5307:          if(firstwo==0){
1.257     brouard  5308:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5309:            firstwo=1;
                   5310:          }
1.257     brouard  5311:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5312:        }
1.257     brouard  5313:       }else{ /* if date of interview is unknown */
1.227     brouard  5314:        /* death is known but not confirmed by death status at any wave */
                   5315:        if(firstfour==0){
                   5316:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5317:          firstfour=1;
                   5318:        }
                   5319:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5320:       }
1.224     brouard  5321:     } /* end if date of death is known */
                   5322: #endif
                   5323:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5324:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5325:     if(mi==0){
                   5326:       nbwarn++;
                   5327:       if(first==0){
1.227     brouard  5328:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5329:        first=1;
1.126     brouard  5330:       }
                   5331:       if(first==1){
1.227     brouard  5332:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5333:       }
                   5334:     } /* end mi==0 */
                   5335:   } /* End individuals */
1.214     brouard  5336:   /* wav and mw are no more changed */
1.223     brouard  5337:        
1.214     brouard  5338:   
1.126     brouard  5339:   for(i=1; i<=imx; i++){
                   5340:     for(mi=1; mi<wav[i];mi++){
                   5341:       if (stepm <=0)
1.227     brouard  5342:        dh[mi][i]=1;
1.126     brouard  5343:       else{
1.260     brouard  5344:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5345:          if (agedc[i] < 2*AGESUP) {
                   5346:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5347:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5348:            else if(j<0){
                   5349:              nberr++;
                   5350:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5351:              j=1; /* Temporary Dangerous patch */
                   5352:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5353:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5354:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5355:            }
                   5356:            k=k+1;
                   5357:            if (j >= jmax){
                   5358:              jmax=j;
                   5359:              ijmax=i;
                   5360:            }
                   5361:            if (j <= jmin){
                   5362:              jmin=j;
                   5363:              ijmin=i;
                   5364:            }
                   5365:            sum=sum+j;
                   5366:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5367:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5368:          }
                   5369:        }
                   5370:        else{
                   5371:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5372: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5373:                                        
1.227     brouard  5374:          k=k+1;
                   5375:          if (j >= jmax) {
                   5376:            jmax=j;
                   5377:            ijmax=i;
                   5378:          }
                   5379:          else if (j <= jmin){
                   5380:            jmin=j;
                   5381:            ijmin=i;
                   5382:          }
                   5383:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5384:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5385:          if(j<0){
                   5386:            nberr++;
                   5387:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5388:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5389:          }
                   5390:          sum=sum+j;
                   5391:        }
                   5392:        jk= j/stepm;
                   5393:        jl= j -jk*stepm;
                   5394:        ju= j -(jk+1)*stepm;
                   5395:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5396:          if(jl==0){
                   5397:            dh[mi][i]=jk;
                   5398:            bh[mi][i]=0;
                   5399:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5400:                  * to avoid the price of an extra matrix product in likelihood */
                   5401:            dh[mi][i]=jk+1;
                   5402:            bh[mi][i]=ju;
                   5403:          }
                   5404:        }else{
                   5405:          if(jl <= -ju){
                   5406:            dh[mi][i]=jk;
                   5407:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5408:                                 * is higher than the multiple of stepm and negative otherwise.
                   5409:                                 */
                   5410:          }
                   5411:          else{
                   5412:            dh[mi][i]=jk+1;
                   5413:            bh[mi][i]=ju;
                   5414:          }
                   5415:          if(dh[mi][i]==0){
                   5416:            dh[mi][i]=1; /* At least one step */
                   5417:            bh[mi][i]=ju; /* At least one step */
                   5418:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5419:          }
                   5420:        } /* end if mle */
1.126     brouard  5421:       }
                   5422:     } /* end wave */
                   5423:   }
                   5424:   jmean=sum/k;
                   5425:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5426:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5427: }
1.126     brouard  5428: 
                   5429: /*********** Tricode ****************************/
1.220     brouard  5430:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5431:  {
                   5432:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5433:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5434:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5435:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5436:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5437:     */
1.130     brouard  5438: 
1.242     brouard  5439:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5440:    int modmaxcovj=0; /* Modality max of covariates j */
                   5441:    int cptcode=0; /* Modality max of covariates j */
                   5442:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5443: 
                   5444: 
1.242     brouard  5445:    /* cptcoveff=0;  */
                   5446:    /* *cptcov=0; */
1.126     brouard  5447:  
1.242     brouard  5448:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5449:    for (k=1; k <= maxncov; k++)
                   5450:      for(j=1; j<=2; j++)
                   5451:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5452: 
1.242     brouard  5453:    /* Loop on covariates without age and products and no quantitative variable */
                   5454:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5455:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5456:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5457:        switch(Fixed[k]) {
                   5458:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5459:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5460:           ij=(int)(covar[Tvar[k]][i]);
                   5461:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5462:            * If product of Vn*Vm, still boolean *:
                   5463:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5464:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5465:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5466:              modality of the nth covariate of individual i. */
                   5467:           if (ij > modmaxcovj)
                   5468:             modmaxcovj=ij; 
                   5469:           else if (ij < modmincovj) 
                   5470:             modmincovj=ij; 
1.287     brouard  5471:           if (ij <0 || ij >1 ){
                   5472:             printf("Information, IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5473:             fprintf(ficlog,"Information, currently IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5474:           }
                   5475:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5476:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5477:             exit(1);
                   5478:           }else
                   5479:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5480:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5481:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5482:           /* getting the maximum value of the modality of the covariate
                   5483:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5484:              female ies 1, then modmaxcovj=1.
                   5485:           */
                   5486:         } /* end for loop on individuals i */
                   5487:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5488:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5489:         cptcode=modmaxcovj;
                   5490:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5491:         /*for (i=0; i<=cptcode; i++) {*/
                   5492:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5493:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5494:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5495:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5496:             if( j != -1){
                   5497:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5498:                                  covariate for which somebody answered excluding 
                   5499:                                  undefined. Usually 2: 0 and 1. */
                   5500:             }
                   5501:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5502:                                     covariate for which somebody answered including 
                   5503:                                     undefined. Usually 3: -1, 0 and 1. */
                   5504:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5505:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5506:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5507:                        
1.242     brouard  5508:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5509:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5510:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5511:         /* modmincovj=3; modmaxcovj = 7; */
                   5512:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5513:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5514:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5515:         /* nbcode[Tvar[j]][ij]=k; */
                   5516:         /* nbcode[Tvar[j]][1]=0; */
                   5517:         /* nbcode[Tvar[j]][2]=1; */
                   5518:         /* nbcode[Tvar[j]][3]=2; */
                   5519:         /* To be continued (not working yet). */
                   5520:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5521: 
                   5522:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5523:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5524:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5525:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5526:         /*, could be restored in the future */
                   5527:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5528:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5529:             break;
                   5530:           }
                   5531:           ij++;
1.287     brouard  5532:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5533:           cptcode = ij; /* New max modality for covar j */
                   5534:         } /* end of loop on modality i=-1 to 1 or more */
                   5535:         break;
                   5536:        case 1: /* Testing on varying covariate, could be simple and
                   5537:                * should look at waves or product of fixed *
                   5538:                * varying. No time to test -1, assuming 0 and 1 only */
                   5539:         ij=0;
                   5540:         for(i=0; i<=1;i++){
                   5541:           nbcode[Tvar[k]][++ij]=i;
                   5542:         }
                   5543:         break;
                   5544:        default:
                   5545:         break;
                   5546:        } /* end switch */
                   5547:      } /* end dummy test */
1.287     brouard  5548:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5549:   
                   5550:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5551:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5552:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5553:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5554:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5555:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5556:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5557:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5558:   
                   5559:    ij=0;
                   5560:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5561:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5562:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5563:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5564:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5565:        /* If product not in single variable we don't print results */
                   5566:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5567:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5568:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5569:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5570:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5571:        if(Fixed[k]!=0)
                   5572:         anyvaryingduminmodel=1;
                   5573:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5574:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5575:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5576:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5577:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5578:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5579:      } 
                   5580:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5581:    /* ij--; */
                   5582:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5583:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5584:                * because they can be excluded from the model and real
                   5585:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5586:    for(j=ij+1; j<= cptcovt; j++){
                   5587:      Tvaraff[j]=0;
                   5588:      Tmodelind[j]=0;
                   5589:    }
                   5590:    for(j=ntveff+1; j<= cptcovt; j++){
                   5591:      TmodelInvind[j]=0;
                   5592:    }
                   5593:    /* To be sorted */
                   5594:    ;
                   5595:  }
1.126     brouard  5596: 
1.145     brouard  5597: 
1.126     brouard  5598: /*********** Health Expectancies ****************/
                   5599: 
1.235     brouard  5600:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5601: 
                   5602: {
                   5603:   /* Health expectancies, no variances */
1.164     brouard  5604:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5605:   int nhstepma, nstepma; /* Decreasing with age */
                   5606:   double age, agelim, hf;
                   5607:   double ***p3mat;
                   5608:   double eip;
                   5609: 
1.238     brouard  5610:   /* pstamp(ficreseij); */
1.126     brouard  5611:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5612:   fprintf(ficreseij,"# Age");
                   5613:   for(i=1; i<=nlstate;i++){
                   5614:     for(j=1; j<=nlstate;j++){
                   5615:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5616:     }
                   5617:     fprintf(ficreseij," e%1d. ",i);
                   5618:   }
                   5619:   fprintf(ficreseij,"\n");
                   5620: 
                   5621:   
                   5622:   if(estepm < stepm){
                   5623:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5624:   }
                   5625:   else  hstepm=estepm;   
                   5626:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5627:    * This is mainly to measure the difference between two models: for example
                   5628:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5629:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5630:    * progression in between and thus overestimating or underestimating according
                   5631:    * to the curvature of the survival function. If, for the same date, we 
                   5632:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5633:    * to compare the new estimate of Life expectancy with the same linear 
                   5634:    * hypothesis. A more precise result, taking into account a more precise
                   5635:    * curvature will be obtained if estepm is as small as stepm. */
                   5636: 
                   5637:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5638:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5639:      nhstepm is the number of hstepm from age to agelim 
                   5640:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5641:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5642:      and note for a fixed period like estepm months */
                   5643:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5644:      survival function given by stepm (the optimization length). Unfortunately it
                   5645:      means that if the survival funtion is printed only each two years of age and if
                   5646:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5647:      results. So we changed our mind and took the option of the best precision.
                   5648:   */
                   5649:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5650: 
                   5651:   agelim=AGESUP;
                   5652:   /* If stepm=6 months */
                   5653:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5654:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5655:     
                   5656: /* nhstepm age range expressed in number of stepm */
                   5657:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5658:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5659:   /* if (stepm >= YEARM) hstepm=1;*/
                   5660:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5661:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5662: 
                   5663:   for (age=bage; age<=fage; age ++){ 
                   5664:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5665:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5666:     /* if (stepm >= YEARM) hstepm=1;*/
                   5667:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5668: 
                   5669:     /* If stepm=6 months */
                   5670:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5671:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5672:     
1.235     brouard  5673:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5674:     
                   5675:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5676:     
                   5677:     printf("%d|",(int)age);fflush(stdout);
                   5678:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5679:     
                   5680:     /* Computing expectancies */
                   5681:     for(i=1; i<=nlstate;i++)
                   5682:       for(j=1; j<=nlstate;j++)
                   5683:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5684:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5685:          
                   5686:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5687: 
                   5688:        }
                   5689: 
                   5690:     fprintf(ficreseij,"%3.0f",age );
                   5691:     for(i=1; i<=nlstate;i++){
                   5692:       eip=0;
                   5693:       for(j=1; j<=nlstate;j++){
                   5694:        eip +=eij[i][j][(int)age];
                   5695:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5696:       }
                   5697:       fprintf(ficreseij,"%9.4f", eip );
                   5698:     }
                   5699:     fprintf(ficreseij,"\n");
                   5700:     
                   5701:   }
                   5702:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5703:   printf("\n");
                   5704:   fprintf(ficlog,"\n");
                   5705:   
                   5706: }
                   5707: 
1.235     brouard  5708:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5709: 
                   5710: {
                   5711:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5712:      to initial status i, ei. .
1.126     brouard  5713:   */
                   5714:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5715:   int nhstepma, nstepma; /* Decreasing with age */
                   5716:   double age, agelim, hf;
                   5717:   double ***p3matp, ***p3matm, ***varhe;
                   5718:   double **dnewm,**doldm;
                   5719:   double *xp, *xm;
                   5720:   double **gp, **gm;
                   5721:   double ***gradg, ***trgradg;
                   5722:   int theta;
                   5723: 
                   5724:   double eip, vip;
                   5725: 
                   5726:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5727:   xp=vector(1,npar);
                   5728:   xm=vector(1,npar);
                   5729:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5730:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5731:   
                   5732:   pstamp(ficresstdeij);
                   5733:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5734:   fprintf(ficresstdeij,"# Age");
                   5735:   for(i=1; i<=nlstate;i++){
                   5736:     for(j=1; j<=nlstate;j++)
                   5737:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5738:     fprintf(ficresstdeij," e%1d. ",i);
                   5739:   }
                   5740:   fprintf(ficresstdeij,"\n");
                   5741: 
                   5742:   pstamp(ficrescveij);
                   5743:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5744:   fprintf(ficrescveij,"# Age");
                   5745:   for(i=1; i<=nlstate;i++)
                   5746:     for(j=1; j<=nlstate;j++){
                   5747:       cptj= (j-1)*nlstate+i;
                   5748:       for(i2=1; i2<=nlstate;i2++)
                   5749:        for(j2=1; j2<=nlstate;j2++){
                   5750:          cptj2= (j2-1)*nlstate+i2;
                   5751:          if(cptj2 <= cptj)
                   5752:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5753:        }
                   5754:     }
                   5755:   fprintf(ficrescveij,"\n");
                   5756:   
                   5757:   if(estepm < stepm){
                   5758:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5759:   }
                   5760:   else  hstepm=estepm;   
                   5761:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5762:    * This is mainly to measure the difference between two models: for example
                   5763:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5764:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5765:    * progression in between and thus overestimating or underestimating according
                   5766:    * to the curvature of the survival function. If, for the same date, we 
                   5767:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5768:    * to compare the new estimate of Life expectancy with the same linear 
                   5769:    * hypothesis. A more precise result, taking into account a more precise
                   5770:    * curvature will be obtained if estepm is as small as stepm. */
                   5771: 
                   5772:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5773:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5774:      nhstepm is the number of hstepm from age to agelim 
                   5775:      nstepm is the number of stepm from age to agelin. 
                   5776:      Look at hpijx to understand the reason of that which relies in memory size
                   5777:      and note for a fixed period like estepm months */
                   5778:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5779:      survival function given by stepm (the optimization length). Unfortunately it
                   5780:      means that if the survival funtion is printed only each two years of age and if
                   5781:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5782:      results. So we changed our mind and took the option of the best precision.
                   5783:   */
                   5784:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5785: 
                   5786:   /* If stepm=6 months */
                   5787:   /* nhstepm age range expressed in number of stepm */
                   5788:   agelim=AGESUP;
                   5789:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5790:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5791:   /* if (stepm >= YEARM) hstepm=1;*/
                   5792:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5793:   
                   5794:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5795:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5796:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5797:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5798:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5799:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5800: 
                   5801:   for (age=bage; age<=fage; age ++){ 
                   5802:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5803:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5804:     /* if (stepm >= YEARM) hstepm=1;*/
                   5805:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5806:                
1.126     brouard  5807:     /* If stepm=6 months */
                   5808:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5809:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5810:     
                   5811:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5812:                
1.126     brouard  5813:     /* Computing  Variances of health expectancies */
                   5814:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5815:        decrease memory allocation */
                   5816:     for(theta=1; theta <=npar; theta++){
                   5817:       for(i=1; i<=npar; i++){ 
1.222     brouard  5818:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5819:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5820:       }
1.235     brouard  5821:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5822:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5823:                        
1.126     brouard  5824:       for(j=1; j<= nlstate; j++){
1.222     brouard  5825:        for(i=1; i<=nlstate; i++){
                   5826:          for(h=0; h<=nhstepm-1; h++){
                   5827:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5828:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5829:          }
                   5830:        }
1.126     brouard  5831:       }
1.218     brouard  5832:                        
1.126     brouard  5833:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5834:        for(h=0; h<=nhstepm-1; h++){
                   5835:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5836:        }
1.126     brouard  5837:     }/* End theta */
                   5838:     
                   5839:     
                   5840:     for(h=0; h<=nhstepm-1; h++)
                   5841:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5842:        for(theta=1; theta <=npar; theta++)
                   5843:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5844:     
1.218     brouard  5845:                
1.222     brouard  5846:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5847:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5848:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5849:                
1.222     brouard  5850:     printf("%d|",(int)age);fflush(stdout);
                   5851:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5852:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5853:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5854:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5855:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5856:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5857:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5858:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5859:       }
                   5860:     }
1.218     brouard  5861:                
1.126     brouard  5862:     /* Computing expectancies */
1.235     brouard  5863:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5864:     for(i=1; i<=nlstate;i++)
                   5865:       for(j=1; j<=nlstate;j++)
1.222     brouard  5866:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5867:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5868:                                        
1.222     brouard  5869:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5870:                                        
1.222     brouard  5871:        }
1.269     brouard  5872: 
                   5873:     /* Standard deviation of expectancies ij */                
1.126     brouard  5874:     fprintf(ficresstdeij,"%3.0f",age );
                   5875:     for(i=1; i<=nlstate;i++){
                   5876:       eip=0.;
                   5877:       vip=0.;
                   5878:       for(j=1; j<=nlstate;j++){
1.222     brouard  5879:        eip += eij[i][j][(int)age];
                   5880:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5881:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5882:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5883:       }
                   5884:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5885:     }
                   5886:     fprintf(ficresstdeij,"\n");
1.218     brouard  5887:                
1.269     brouard  5888:     /* Variance of expectancies ij */          
1.126     brouard  5889:     fprintf(ficrescveij,"%3.0f",age );
                   5890:     for(i=1; i<=nlstate;i++)
                   5891:       for(j=1; j<=nlstate;j++){
1.222     brouard  5892:        cptj= (j-1)*nlstate+i;
                   5893:        for(i2=1; i2<=nlstate;i2++)
                   5894:          for(j2=1; j2<=nlstate;j2++){
                   5895:            cptj2= (j2-1)*nlstate+i2;
                   5896:            if(cptj2 <= cptj)
                   5897:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5898:          }
1.126     brouard  5899:       }
                   5900:     fprintf(ficrescveij,"\n");
1.218     brouard  5901:                
1.126     brouard  5902:   }
                   5903:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5904:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5905:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5906:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5907:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5908:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5909:   printf("\n");
                   5910:   fprintf(ficlog,"\n");
1.218     brouard  5911:        
1.126     brouard  5912:   free_vector(xm,1,npar);
                   5913:   free_vector(xp,1,npar);
                   5914:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5915:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5916:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5917: }
1.218     brouard  5918:  
1.126     brouard  5919: /************ Variance ******************/
1.235     brouard  5920:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5921:  {
1.279     brouard  5922:    /** Variance of health expectancies 
                   5923:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5924:     * double **newm;
                   5925:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5926:     */
1.218     brouard  5927:   
                   5928:    /* int movingaverage(); */
                   5929:    double **dnewm,**doldm;
                   5930:    double **dnewmp,**doldmp;
                   5931:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  5932:    int first=0;
1.218     brouard  5933:    int k;
                   5934:    double *xp;
1.279     brouard  5935:    double **gp, **gm;  /**< for var eij */
                   5936:    double ***gradg, ***trgradg; /**< for var eij */
                   5937:    double **gradgp, **trgradgp; /**< for var p point j */
                   5938:    double *gpp, *gmp; /**< for var p point j */
                   5939:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5940:    double ***p3mat;
                   5941:    double age,agelim, hf;
                   5942:    /* double ***mobaverage; */
                   5943:    int theta;
                   5944:    char digit[4];
                   5945:    char digitp[25];
                   5946: 
                   5947:    char fileresprobmorprev[FILENAMELENGTH];
                   5948: 
                   5949:    if(popbased==1){
                   5950:      if(mobilav!=0)
                   5951:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5952:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5953:    }
                   5954:    else 
                   5955:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5956: 
1.218     brouard  5957:    /* if (mobilav!=0) { */
                   5958:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5959:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5960:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5961:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5962:    /*   } */
                   5963:    /* } */
                   5964: 
                   5965:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5966:    sprintf(digit,"%-d",ij);
                   5967:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5968:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5969:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5970:    strcat(fileresprobmorprev,fileresu);
                   5971:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5972:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5973:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5974:    }
                   5975:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5976:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5977:    pstamp(ficresprobmorprev);
                   5978:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5979:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5980:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5981:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5982:    }
                   5983:    for(j=1;j<=cptcoveff;j++) 
                   5984:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5985:    fprintf(ficresprobmorprev,"\n");
                   5986: 
1.218     brouard  5987:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5988:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5989:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5990:      for(i=1; i<=nlstate;i++)
                   5991:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5992:    }  
                   5993:    fprintf(ficresprobmorprev,"\n");
                   5994:   
                   5995:    fprintf(ficgp,"\n# Routine varevsij");
                   5996:    fprintf(ficgp,"\nunset title \n");
                   5997:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5998:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5999:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6000: 
1.218     brouard  6001:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6002:    pstamp(ficresvij);
                   6003:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6004:    if(popbased==1)
                   6005:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6006:    else
                   6007:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6008:    fprintf(ficresvij,"# Age");
                   6009:    for(i=1; i<=nlstate;i++)
                   6010:      for(j=1; j<=nlstate;j++)
                   6011:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6012:    fprintf(ficresvij,"\n");
                   6013: 
                   6014:    xp=vector(1,npar);
                   6015:    dnewm=matrix(1,nlstate,1,npar);
                   6016:    doldm=matrix(1,nlstate,1,nlstate);
                   6017:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6018:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6019: 
                   6020:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6021:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6022:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6023:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6024:   
1.218     brouard  6025:    if(estepm < stepm){
                   6026:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6027:    }
                   6028:    else  hstepm=estepm;   
                   6029:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6030:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6031:       nhstepm is the number of hstepm from age to agelim 
                   6032:       nstepm is the number of stepm from age to agelim. 
                   6033:       Look at function hpijx to understand why because of memory size limitations, 
                   6034:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6035:       survival function given by stepm (the optimization length). Unfortunately it
                   6036:       means that if the survival funtion is printed every two years of age and if
                   6037:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6038:       results. So we changed our mind and took the option of the best precision.
                   6039:    */
                   6040:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6041:    agelim = AGESUP;
                   6042:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6043:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6044:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6045:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6046:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6047:      gp=matrix(0,nhstepm,1,nlstate);
                   6048:      gm=matrix(0,nhstepm,1,nlstate);
                   6049:                
                   6050:                
                   6051:      for(theta=1; theta <=npar; theta++){
                   6052:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6053:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6054:        }
1.279     brouard  6055:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6056:        * returns into prlim .
1.288     brouard  6057:        */
1.242     brouard  6058:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6059: 
                   6060:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6061:        if (popbased==1) {
                   6062:         if(mobilav ==0){
                   6063:           for(i=1; i<=nlstate;i++)
                   6064:             prlim[i][i]=probs[(int)age][i][ij];
                   6065:         }else{ /* mobilav */ 
                   6066:           for(i=1; i<=nlstate;i++)
                   6067:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6068:         }
                   6069:        }
1.295     brouard  6070:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6071:        */                      
                   6072:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6073:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6074:        * at horizon h in state j including mortality.
                   6075:        */
1.218     brouard  6076:        for(j=1; j<= nlstate; j++){
                   6077:         for(h=0; h<=nhstepm; h++){
                   6078:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6079:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6080:         }
                   6081:        }
1.279     brouard  6082:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6083:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6084:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6085:        */
                   6086:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6087:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6088:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6089:        }
                   6090:        
                   6091:        /* Again with minus shift */
1.218     brouard  6092:                        
                   6093:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6094:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6095: 
1.242     brouard  6096:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6097:                        
                   6098:        if (popbased==1) {
                   6099:         if(mobilav ==0){
                   6100:           for(i=1; i<=nlstate;i++)
                   6101:             prlim[i][i]=probs[(int)age][i][ij];
                   6102:         }else{ /* mobilav */ 
                   6103:           for(i=1; i<=nlstate;i++)
                   6104:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6105:         }
                   6106:        }
                   6107:                        
1.235     brouard  6108:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6109:                        
                   6110:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6111:         for(h=0; h<=nhstepm; h++){
                   6112:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6113:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6114:         }
                   6115:        }
                   6116:        /* This for computing probability of death (h=1 means
                   6117:          computed over hstepm matrices product = hstepm*stepm months) 
                   6118:          as a weighted average of prlim.
                   6119:        */
                   6120:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6121:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6122:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6123:        }    
1.279     brouard  6124:        /* end shifting computations */
                   6125: 
                   6126:        /**< Computing gradient matrix at horizon h 
                   6127:        */
1.218     brouard  6128:        for(j=1; j<= nlstate; j++) /* vareij */
                   6129:         for(h=0; h<=nhstepm; h++){
                   6130:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6131:         }
1.279     brouard  6132:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6133:        */
                   6134:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6135:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6136:        }
                   6137:                        
                   6138:      } /* End theta */
1.279     brouard  6139:      
                   6140:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6141:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6142:                
                   6143:      for(h=0; h<=nhstepm; h++) /* veij */
                   6144:        for(j=1; j<=nlstate;j++)
                   6145:         for(theta=1; theta <=npar; theta++)
                   6146:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6147:                
                   6148:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6149:        for(theta=1; theta <=npar; theta++)
                   6150:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6151:      /**< as well as its transposed matrix 
                   6152:       */               
1.218     brouard  6153:                
                   6154:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6155:      for(i=1;i<=nlstate;i++)
                   6156:        for(j=1;j<=nlstate;j++)
                   6157:         vareij[i][j][(int)age] =0.;
1.279     brouard  6158: 
                   6159:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6160:       * and k (nhstepm) formula 15 of article
                   6161:       * Lievre-Brouard-Heathcote
                   6162:       */
                   6163:      
1.218     brouard  6164:      for(h=0;h<=nhstepm;h++){
                   6165:        for(k=0;k<=nhstepm;k++){
                   6166:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6167:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6168:         for(i=1;i<=nlstate;i++)
                   6169:           for(j=1;j<=nlstate;j++)
                   6170:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6171:        }
                   6172:      }
                   6173:                
1.279     brouard  6174:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6175:       * p.j overall mortality formula 49 but computed directly because
                   6176:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6177:       * wix is independent of theta.
                   6178:       */
1.218     brouard  6179:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6180:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6181:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6182:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6183:         varppt[j][i]=doldmp[j][i];
                   6184:      /* end ppptj */
                   6185:      /*  x centered again */
                   6186:                
1.242     brouard  6187:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6188:                
                   6189:      if (popbased==1) {
                   6190:        if(mobilav ==0){
                   6191:         for(i=1; i<=nlstate;i++)
                   6192:           prlim[i][i]=probs[(int)age][i][ij];
                   6193:        }else{ /* mobilav */ 
                   6194:         for(i=1; i<=nlstate;i++)
                   6195:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6196:        }
                   6197:      }
                   6198:                
                   6199:      /* This for computing probability of death (h=1 means
                   6200:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6201:        as a weighted average of prlim.
                   6202:      */
1.235     brouard  6203:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6204:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6205:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6206:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6207:      }    
                   6208:      /* end probability of death */
                   6209:                
                   6210:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6211:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6212:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6213:        for(i=1; i<=nlstate;i++){
                   6214:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6215:        }
                   6216:      } 
                   6217:      fprintf(ficresprobmorprev,"\n");
                   6218:                
                   6219:      fprintf(ficresvij,"%.0f ",age );
                   6220:      for(i=1; i<=nlstate;i++)
                   6221:        for(j=1; j<=nlstate;j++){
                   6222:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6223:        }
                   6224:      fprintf(ficresvij,"\n");
                   6225:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6226:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6227:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6228:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6229:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6230:    } /* End age */
                   6231:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6232:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6233:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6234:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6235:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6236:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6237:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6238:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6239:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6240:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6241:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6242:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6243:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6244:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6245:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6246:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6247:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6248:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6249:     */
1.218     brouard  6250:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6251:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6252: 
1.218     brouard  6253:    free_vector(xp,1,npar);
                   6254:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6255:    free_matrix(dnewm,1,nlstate,1,npar);
                   6256:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6257:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6258:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6259:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6260:    fclose(ficresprobmorprev);
                   6261:    fflush(ficgp);
                   6262:    fflush(fichtm); 
                   6263:  }  /* end varevsij */
1.126     brouard  6264: 
                   6265: /************ Variance of prevlim ******************/
1.269     brouard  6266:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6267: {
1.205     brouard  6268:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6269:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6270: 
1.268     brouard  6271:   double **dnewmpar,**doldm;
1.126     brouard  6272:   int i, j, nhstepm, hstepm;
                   6273:   double *xp;
                   6274:   double *gp, *gm;
                   6275:   double **gradg, **trgradg;
1.208     brouard  6276:   double **mgm, **mgp;
1.126     brouard  6277:   double age,agelim;
                   6278:   int theta;
                   6279:   
                   6280:   pstamp(ficresvpl);
1.288     brouard  6281:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6282:   fprintf(ficresvpl,"# Age ");
                   6283:   if(nresult >=1)
                   6284:     fprintf(ficresvpl," Result# ");
1.126     brouard  6285:   for(i=1; i<=nlstate;i++)
                   6286:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6287:   fprintf(ficresvpl,"\n");
                   6288: 
                   6289:   xp=vector(1,npar);
1.268     brouard  6290:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6291:   doldm=matrix(1,nlstate,1,nlstate);
                   6292:   
                   6293:   hstepm=1*YEARM; /* Every year of age */
                   6294:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6295:   agelim = AGESUP;
                   6296:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6297:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6298:     if (stepm >= YEARM) hstepm=1;
                   6299:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6300:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6301:     mgp=matrix(1,npar,1,nlstate);
                   6302:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6303:     gp=vector(1,nlstate);
                   6304:     gm=vector(1,nlstate);
                   6305: 
                   6306:     for(theta=1; theta <=npar; theta++){
                   6307:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6308:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6309:       }
1.288     brouard  6310:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6311:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6312:       /* else */
                   6313:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6314:       for(i=1;i<=nlstate;i++){
1.126     brouard  6315:        gp[i] = prlim[i][i];
1.208     brouard  6316:        mgp[theta][i] = prlim[i][i];
                   6317:       }
1.126     brouard  6318:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6319:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6320:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6321:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6322:       /* else */
                   6323:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6324:       for(i=1;i<=nlstate;i++){
1.126     brouard  6325:        gm[i] = prlim[i][i];
1.208     brouard  6326:        mgm[theta][i] = prlim[i][i];
                   6327:       }
1.126     brouard  6328:       for(i=1;i<=nlstate;i++)
                   6329:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6330:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6331:     } /* End theta */
                   6332: 
                   6333:     trgradg =matrix(1,nlstate,1,npar);
                   6334: 
                   6335:     for(j=1; j<=nlstate;j++)
                   6336:       for(theta=1; theta <=npar; theta++)
                   6337:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6338:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6339:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6340:     /*   for(j=1; j<=nlstate;j++){ */
                   6341:     /*         printf(" %d ",j); */
                   6342:     /*         for(theta=1; theta <=npar; theta++) */
                   6343:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6344:     /*         printf("\n "); */
                   6345:     /*   } */
                   6346:     /* } */
                   6347:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6348:     /*   printf("\n gradg %d ",(int)age); */
                   6349:     /*   for(j=1; j<=nlstate;j++){ */
                   6350:     /*         printf("%d ",j); */
                   6351:     /*         for(theta=1; theta <=npar; theta++) */
                   6352:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6353:     /*         printf("\n "); */
                   6354:     /*   } */
                   6355:     /* } */
1.126     brouard  6356: 
                   6357:     for(i=1;i<=nlstate;i++)
                   6358:       varpl[i][(int)age] =0.;
1.209     brouard  6359:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6360:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6361:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6362:     }else{
1.268     brouard  6363:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6364:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6365:     }
1.126     brouard  6366:     for(i=1;i<=nlstate;i++)
                   6367:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6368: 
                   6369:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6370:     if(nresult >=1)
                   6371:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6372:     for(i=1; i<=nlstate;i++){
1.126     brouard  6373:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6374:       /* for(j=1;j<=nlstate;j++) */
                   6375:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6376:     }
1.126     brouard  6377:     fprintf(ficresvpl,"\n");
                   6378:     free_vector(gp,1,nlstate);
                   6379:     free_vector(gm,1,nlstate);
1.208     brouard  6380:     free_matrix(mgm,1,npar,1,nlstate);
                   6381:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6382:     free_matrix(gradg,1,npar,1,nlstate);
                   6383:     free_matrix(trgradg,1,nlstate,1,npar);
                   6384:   } /* End age */
                   6385: 
                   6386:   free_vector(xp,1,npar);
                   6387:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6388:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6389: 
                   6390: }
                   6391: 
                   6392: 
                   6393: /************ Variance of backprevalence limit ******************/
1.269     brouard  6394:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6395: {
                   6396:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6397:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6398: 
                   6399:   double **dnewmpar,**doldm;
                   6400:   int i, j, nhstepm, hstepm;
                   6401:   double *xp;
                   6402:   double *gp, *gm;
                   6403:   double **gradg, **trgradg;
                   6404:   double **mgm, **mgp;
                   6405:   double age,agelim;
                   6406:   int theta;
                   6407:   
                   6408:   pstamp(ficresvbl);
                   6409:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6410:   fprintf(ficresvbl,"# Age ");
                   6411:   if(nresult >=1)
                   6412:     fprintf(ficresvbl," Result# ");
                   6413:   for(i=1; i<=nlstate;i++)
                   6414:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6415:   fprintf(ficresvbl,"\n");
                   6416: 
                   6417:   xp=vector(1,npar);
                   6418:   dnewmpar=matrix(1,nlstate,1,npar);
                   6419:   doldm=matrix(1,nlstate,1,nlstate);
                   6420:   
                   6421:   hstepm=1*YEARM; /* Every year of age */
                   6422:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6423:   agelim = AGEINF;
                   6424:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6425:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6426:     if (stepm >= YEARM) hstepm=1;
                   6427:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6428:     gradg=matrix(1,npar,1,nlstate);
                   6429:     mgp=matrix(1,npar,1,nlstate);
                   6430:     mgm=matrix(1,npar,1,nlstate);
                   6431:     gp=vector(1,nlstate);
                   6432:     gm=vector(1,nlstate);
                   6433: 
                   6434:     for(theta=1; theta <=npar; theta++){
                   6435:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6436:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6437:       }
                   6438:       if(mobilavproj > 0 )
                   6439:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6440:       else
                   6441:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6442:       for(i=1;i<=nlstate;i++){
                   6443:        gp[i] = bprlim[i][i];
                   6444:        mgp[theta][i] = bprlim[i][i];
                   6445:       }
                   6446:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6447:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6448:        if(mobilavproj > 0 )
                   6449:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6450:        else
                   6451:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6452:       for(i=1;i<=nlstate;i++){
                   6453:        gm[i] = bprlim[i][i];
                   6454:        mgm[theta][i] = bprlim[i][i];
                   6455:       }
                   6456:       for(i=1;i<=nlstate;i++)
                   6457:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6458:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6459:     } /* End theta */
                   6460: 
                   6461:     trgradg =matrix(1,nlstate,1,npar);
                   6462: 
                   6463:     for(j=1; j<=nlstate;j++)
                   6464:       for(theta=1; theta <=npar; theta++)
                   6465:        trgradg[j][theta]=gradg[theta][j];
                   6466:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6467:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6468:     /*   for(j=1; j<=nlstate;j++){ */
                   6469:     /*         printf(" %d ",j); */
                   6470:     /*         for(theta=1; theta <=npar; theta++) */
                   6471:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6472:     /*         printf("\n "); */
                   6473:     /*   } */
                   6474:     /* } */
                   6475:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6476:     /*   printf("\n gradg %d ",(int)age); */
                   6477:     /*   for(j=1; j<=nlstate;j++){ */
                   6478:     /*         printf("%d ",j); */
                   6479:     /*         for(theta=1; theta <=npar; theta++) */
                   6480:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6481:     /*         printf("\n "); */
                   6482:     /*   } */
                   6483:     /* } */
                   6484: 
                   6485:     for(i=1;i<=nlstate;i++)
                   6486:       varbpl[i][(int)age] =0.;
                   6487:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6488:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6489:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6490:     }else{
                   6491:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6492:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6493:     }
                   6494:     for(i=1;i<=nlstate;i++)
                   6495:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6496: 
                   6497:     fprintf(ficresvbl,"%.0f ",age );
                   6498:     if(nresult >=1)
                   6499:       fprintf(ficresvbl,"%d ",nres );
                   6500:     for(i=1; i<=nlstate;i++)
                   6501:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6502:     fprintf(ficresvbl,"\n");
                   6503:     free_vector(gp,1,nlstate);
                   6504:     free_vector(gm,1,nlstate);
                   6505:     free_matrix(mgm,1,npar,1,nlstate);
                   6506:     free_matrix(mgp,1,npar,1,nlstate);
                   6507:     free_matrix(gradg,1,npar,1,nlstate);
                   6508:     free_matrix(trgradg,1,nlstate,1,npar);
                   6509:   } /* End age */
                   6510: 
                   6511:   free_vector(xp,1,npar);
                   6512:   free_matrix(doldm,1,nlstate,1,npar);
                   6513:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6514: 
                   6515: }
                   6516: 
                   6517: /************ Variance of one-step probabilities  ******************/
                   6518: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6519:  {
                   6520:    int i, j=0,  k1, l1, tj;
                   6521:    int k2, l2, j1,  z1;
                   6522:    int k=0, l;
                   6523:    int first=1, first1, first2;
                   6524:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6525:    double **dnewm,**doldm;
                   6526:    double *xp;
                   6527:    double *gp, *gm;
                   6528:    double **gradg, **trgradg;
                   6529:    double **mu;
                   6530:    double age, cov[NCOVMAX+1];
                   6531:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6532:    int theta;
                   6533:    char fileresprob[FILENAMELENGTH];
                   6534:    char fileresprobcov[FILENAMELENGTH];
                   6535:    char fileresprobcor[FILENAMELENGTH];
                   6536:    double ***varpij;
                   6537: 
                   6538:    strcpy(fileresprob,"PROB_"); 
                   6539:    strcat(fileresprob,fileres);
                   6540:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6541:      printf("Problem with resultfile: %s\n", fileresprob);
                   6542:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6543:    }
                   6544:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6545:    strcat(fileresprobcov,fileresu);
                   6546:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6547:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6548:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6549:    }
                   6550:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6551:    strcat(fileresprobcor,fileresu);
                   6552:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6553:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6554:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6555:    }
                   6556:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6557:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6558:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6559:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6560:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6561:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6562:    pstamp(ficresprob);
                   6563:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6564:    fprintf(ficresprob,"# Age");
                   6565:    pstamp(ficresprobcov);
                   6566:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6567:    fprintf(ficresprobcov,"# Age");
                   6568:    pstamp(ficresprobcor);
                   6569:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6570:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6571: 
                   6572: 
1.222     brouard  6573:    for(i=1; i<=nlstate;i++)
                   6574:      for(j=1; j<=(nlstate+ndeath);j++){
                   6575:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6576:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6577:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6578:      }  
                   6579:    /* fprintf(ficresprob,"\n");
                   6580:       fprintf(ficresprobcov,"\n");
                   6581:       fprintf(ficresprobcor,"\n");
                   6582:    */
                   6583:    xp=vector(1,npar);
                   6584:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6585:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6586:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6587:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6588:    first=1;
                   6589:    fprintf(ficgp,"\n# Routine varprob");
                   6590:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6591:    fprintf(fichtm,"\n");
                   6592: 
1.288     brouard  6593:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6594:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6595:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6596: and drawn. It helps understanding how is the covariance between two incidences.\
                   6597:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6598:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6599: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6600: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6601: standard deviations wide on each axis. <br>\
                   6602:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6603:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6604: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6605: 
1.222     brouard  6606:    cov[1]=1;
                   6607:    /* tj=cptcoveff; */
1.225     brouard  6608:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6609:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6610:    j1=0;
1.224     brouard  6611:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6612:      if  (cptcovn>0) {
                   6613:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6614:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6615:        fprintf(ficresprob, "**********\n#\n");
                   6616:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6617:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6618:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6619:                        
1.222     brouard  6620:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6621:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6622:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6623:                        
                   6624:                        
1.222     brouard  6625:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6626:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6627:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6628:                        
1.222     brouard  6629:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6630:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6631:        fprintf(ficresprobcor, "**********\n#");    
                   6632:        if(invalidvarcomb[j1]){
                   6633:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6634:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6635:         continue;
                   6636:        }
                   6637:      }
                   6638:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6639:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6640:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6641:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6642:      for (age=bage; age<=fage; age ++){ 
                   6643:        cov[2]=age;
                   6644:        if(nagesqr==1)
                   6645:         cov[3]= age*age;
                   6646:        for (k=1; k<=cptcovn;k++) {
                   6647:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6648:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6649:                                                                    * 1  1 1 1 1
                   6650:                                                                    * 2  2 1 1 1
                   6651:                                                                    * 3  1 2 1 1
                   6652:                                                                    */
                   6653:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6654:        }
                   6655:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6656:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6657:        for (k=1; k<=cptcovprod;k++)
                   6658:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6659:                        
                   6660:                        
1.222     brouard  6661:        for(theta=1; theta <=npar; theta++){
                   6662:         for(i=1; i<=npar; i++)
                   6663:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6664:                                
1.222     brouard  6665:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6666:                                
1.222     brouard  6667:         k=0;
                   6668:         for(i=1; i<= (nlstate); i++){
                   6669:           for(j=1; j<=(nlstate+ndeath);j++){
                   6670:             k=k+1;
                   6671:             gp[k]=pmmij[i][j];
                   6672:           }
                   6673:         }
1.220     brouard  6674:                                
1.222     brouard  6675:         for(i=1; i<=npar; i++)
                   6676:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6677:                                
1.222     brouard  6678:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6679:         k=0;
                   6680:         for(i=1; i<=(nlstate); i++){
                   6681:           for(j=1; j<=(nlstate+ndeath);j++){
                   6682:             k=k+1;
                   6683:             gm[k]=pmmij[i][j];
                   6684:           }
                   6685:         }
1.220     brouard  6686:                                
1.222     brouard  6687:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6688:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6689:        }
1.126     brouard  6690: 
1.222     brouard  6691:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6692:         for(theta=1; theta <=npar; theta++)
                   6693:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6694:                        
1.222     brouard  6695:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6696:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6697:                        
1.222     brouard  6698:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6699:                        
1.222     brouard  6700:        k=0;
                   6701:        for(i=1; i<=(nlstate); i++){
                   6702:         for(j=1; j<=(nlstate+ndeath);j++){
                   6703:           k=k+1;
                   6704:           mu[k][(int) age]=pmmij[i][j];
                   6705:         }
                   6706:        }
                   6707:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6708:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6709:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6710:                        
1.222     brouard  6711:        /*printf("\n%d ",(int)age);
                   6712:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6713:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6714:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6715:         }*/
1.220     brouard  6716:                        
1.222     brouard  6717:        fprintf(ficresprob,"\n%d ",(int)age);
                   6718:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6719:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6720:                        
1.222     brouard  6721:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6722:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6723:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6724:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6725:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6726:        }
                   6727:        i=0;
                   6728:        for (k=1; k<=(nlstate);k++){
                   6729:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6730:           i++;
                   6731:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6732:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6733:           for (j=1; j<=i;j++){
                   6734:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6735:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6736:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6737:           }
                   6738:         }
                   6739:        }/* end of loop for state */
                   6740:      } /* end of loop for age */
                   6741:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6742:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6743:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6744:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6745:     
                   6746:      /* Confidence intervalle of pij  */
                   6747:      /*
                   6748:        fprintf(ficgp,"\nunset parametric;unset label");
                   6749:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6750:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6751:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6752:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6753:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6754:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6755:      */
                   6756:                
                   6757:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6758:      first1=1;first2=2;
                   6759:      for (k2=1; k2<=(nlstate);k2++){
                   6760:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6761:         if(l2==k2) continue;
                   6762:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6763:         for (k1=1; k1<=(nlstate);k1++){
                   6764:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6765:             if(l1==k1) continue;
                   6766:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6767:             if(i<=j) continue;
                   6768:             for (age=bage; age<=fage; age ++){ 
                   6769:               if ((int)age %5==0){
                   6770:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6771:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6772:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6773:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6774:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6775:                 c12=cv12/sqrt(v1*v2);
                   6776:                 /* Computing eigen value of matrix of covariance */
                   6777:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6778:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6779:                 if ((lc2 <0) || (lc1 <0) ){
                   6780:                   if(first2==1){
                   6781:                     first1=0;
                   6782:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6783:                   }
                   6784:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6785:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6786:                   /* lc2=fabs(lc2); */
                   6787:                 }
1.220     brouard  6788:                                                                
1.222     brouard  6789:                 /* Eigen vectors */
1.280     brouard  6790:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6791:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6792:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6793:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6794:                 }else
                   6795:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6796:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6797:                 v21=(lc1-v1)/cv12*v11;
                   6798:                 v12=-v21;
                   6799:                 v22=v11;
                   6800:                 tnalp=v21/v11;
                   6801:                 if(first1==1){
                   6802:                   first1=0;
                   6803:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6804:                 }
                   6805:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6806:                 /*printf(fignu*/
                   6807:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6808:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6809:                 if(first==1){
                   6810:                   first=0;
                   6811:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6812:                   fprintf(ficgp,"\nset parametric;unset label");
                   6813:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6814:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6815:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6816:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6817: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6818:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6819:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6820:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6821:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6822:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6823:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6824:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6825:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6826:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6827:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6828:                 }else{
                   6829:                   first=0;
                   6830:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6831:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6832:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6833:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6834:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6835:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6836:                 }/* if first */
                   6837:               } /* age mod 5 */
                   6838:             } /* end loop age */
                   6839:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6840:             first=1;
                   6841:           } /*l12 */
                   6842:         } /* k12 */
                   6843:        } /*l1 */
                   6844:      }/* k1 */
                   6845:    }  /* loop on combination of covariates j1 */
                   6846:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6847:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6848:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6849:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6850:    free_vector(xp,1,npar);
                   6851:    fclose(ficresprob);
                   6852:    fclose(ficresprobcov);
                   6853:    fclose(ficresprobcor);
                   6854:    fflush(ficgp);
                   6855:    fflush(fichtmcov);
                   6856:  }
1.126     brouard  6857: 
                   6858: 
                   6859: /******************* Printing html file ***********/
1.201     brouard  6860: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6861:                  int lastpass, int stepm, int weightopt, char model[],\
                   6862:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  6863:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   6864:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   6865:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  6866:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6867: 
                   6868:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6869:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6870: </ul>");
1.237     brouard  6871:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6872: </ul>", model);
1.214     brouard  6873:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6874:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6875:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6876:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6877:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6878:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6879:    fprintf(fichtm,"\
                   6880:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6881:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6882:    fprintf(fichtm,"\
1.217     brouard  6883:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6884:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6885:    fprintf(fichtm,"\
1.288     brouard  6886:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6887:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6888:    fprintf(fichtm,"\
1.288     brouard  6889:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6890:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6891:    fprintf(fichtm,"\
1.211     brouard  6892:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6893:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6894:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6895:    if(prevfcast==1){
                   6896:      fprintf(fichtm,"\
                   6897:  - Prevalence projections by age and states:                           \
1.201     brouard  6898:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6899:    }
1.126     brouard  6900: 
                   6901: 
1.225     brouard  6902:    m=pow(2,cptcoveff);
1.222     brouard  6903:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6904: 
1.264     brouard  6905:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6906: 
                   6907:    jj1=0;
                   6908: 
                   6909:    fprintf(fichtm," \n<ul>");
                   6910:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6911:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6912:      if(m != 1 && TKresult[nres]!= k1)
                   6913:        continue;
                   6914:      jj1++;
                   6915:      if (cptcovn > 0) {
                   6916:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6917:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6918:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6919:        }
                   6920:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6921:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6922:        }
                   6923:        fprintf(fichtm,"\">");
                   6924:        
                   6925:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6926:        fprintf(fichtm,"************ Results for covariates");
                   6927:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6928:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6929:        }
                   6930:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6931:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6932:        }
                   6933:        if(invalidvarcomb[k1]){
                   6934:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6935:         continue;
                   6936:        }
                   6937:        fprintf(fichtm,"</a></li>");
                   6938:      } /* cptcovn >0 */
                   6939:    }
                   6940:      fprintf(fichtm," \n</ul>");
                   6941: 
1.222     brouard  6942:    jj1=0;
1.237     brouard  6943: 
                   6944:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6945:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6946:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6947:        continue;
1.220     brouard  6948: 
1.222     brouard  6949:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6950:      jj1++;
                   6951:      if (cptcovn > 0) {
1.264     brouard  6952:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6953:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6954:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6955:        }
                   6956:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6957:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6958:        }
                   6959:        fprintf(fichtm,"\"</a>");
                   6960:  
1.222     brouard  6961:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6962:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6963:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6964:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6965:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6966:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6967:        }
1.237     brouard  6968:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6969:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6970:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6971:       }
                   6972:        
1.230     brouard  6973:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6974:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6975:        if(invalidvarcomb[k1]){
                   6976:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6977:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6978:         continue;
                   6979:        }
                   6980:      }
                   6981:      /* aij, bij */
1.259     brouard  6982:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6983: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6984:      /* Pij */
1.241     brouard  6985:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6986: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6987:      /* Quasi-incidences */
                   6988:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6989:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6990:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6991: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6992: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6993:      /* Survival functions (period) in state j */
                   6994:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  6995:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6996: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6997:      }
                   6998:      /* State specific survival functions (period) */
                   6999:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7000:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7001:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7002:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7003:      }
1.288     brouard  7004:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7005:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7006:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7007: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7008:      }
1.296     brouard  7009:      if(prevbcast==1){
1.288     brouard  7010:        /* Backward prevalence in each health state */
1.222     brouard  7011:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7012:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7013: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7014:        }
1.217     brouard  7015:      }
1.222     brouard  7016:      if(prevfcast==1){
1.288     brouard  7017:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7018:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  7019:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.296     brouard  7020: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7021:        }
                   7022:      }
1.296     brouard  7023:      if(prevbcast==1){
1.268     brouard  7024:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7025:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7026:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7027:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7028:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   7029: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7030:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7031:        }
                   7032:      }
1.220     brouard  7033:         
1.222     brouard  7034:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  7035:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   7036: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  7037:      }
                   7038:      /* } /\* end i1 *\/ */
                   7039:    }/* End k1 */
                   7040:    fprintf(fichtm,"</ul>");
1.126     brouard  7041: 
1.222     brouard  7042:    fprintf(fichtm,"\
1.126     brouard  7043: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7044:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7045:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7046: But because parameters are usually highly correlated (a higher incidence of disability \
                   7047: and a higher incidence of recovery can give very close observed transition) it might \
                   7048: be very useful to look not only at linear confidence intervals estimated from the \
                   7049: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7050: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7051: covariance matrix of the one-step probabilities. \
                   7052: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7053: 
1.222     brouard  7054:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7055:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7056:    fprintf(fichtm,"\
1.126     brouard  7057:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7058:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7059: 
1.222     brouard  7060:    fprintf(fichtm,"\
1.126     brouard  7061:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7062:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7063:    fprintf(fichtm,"\
1.126     brouard  7064:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7065:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7066:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7067:    fprintf(fichtm,"\
1.126     brouard  7068:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7069:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7070:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7071:    fprintf(fichtm,"\
1.288     brouard  7072:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7073:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7074:    fprintf(fichtm,"\
1.128     brouard  7075:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7076:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7077:    fprintf(fichtm,"\
1.288     brouard  7078:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7079:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7080: 
                   7081: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7082: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7083: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7084: /*     <br>",fileres,fileres,fileres,fileres); */
                   7085: /*  else  */
                   7086: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7087:    fflush(fichtm);
                   7088:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7089: 
1.225     brouard  7090:    m=pow(2,cptcoveff);
1.222     brouard  7091:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7092: 
1.222     brouard  7093:    jj1=0;
1.237     brouard  7094: 
1.241     brouard  7095:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7096:    for(k1=1; k1<=m;k1++){
1.253     brouard  7097:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7098:        continue;
1.222     brouard  7099:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7100:      jj1++;
1.126     brouard  7101:      if (cptcovn > 0) {
                   7102:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7103:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7104:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7105:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7106:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7107:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7108:       }
                   7109: 
1.126     brouard  7110:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7111: 
1.222     brouard  7112:        if(invalidvarcomb[k1]){
                   7113:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7114:         continue;
                   7115:        }
1.126     brouard  7116:      }
                   7117:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7118:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7119: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7120: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7121:      }
                   7122:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7123: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7124: true period expectancies (those weighted with period prevalences are also\
                   7125:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7126:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7127: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7128:      /* } /\* end i1 *\/ */
                   7129:    }/* End k1 */
1.241     brouard  7130:   }/* End nres */
1.222     brouard  7131:    fprintf(fichtm,"</ul>");
                   7132:    fflush(fichtm);
1.126     brouard  7133: }
                   7134: 
                   7135: /******************* Gnuplot file **************/
1.296     brouard  7136: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7137: 
                   7138:   char dirfileres[132],optfileres[132];
1.264     brouard  7139:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7140:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7141:   int lv=0, vlv=0, kl=0;
1.130     brouard  7142:   int ng=0;
1.201     brouard  7143:   int vpopbased;
1.223     brouard  7144:   int ioffset; /* variable offset for columns */
1.270     brouard  7145:   int iyearc=1; /* variable column for year of projection  */
                   7146:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7147:   int nres=0; /* Index of resultline */
1.266     brouard  7148:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7149: 
1.126     brouard  7150: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7151: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7152: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7153: /*   } */
                   7154: 
                   7155:   /*#ifdef windows */
                   7156:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7157:   /*#endif */
1.225     brouard  7158:   m=pow(2,cptcoveff);
1.126     brouard  7159: 
1.274     brouard  7160:   /* diagram of the model */
                   7161:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7162:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7163:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7164:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7165: 
                   7166:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7167:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7168:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7169:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7170:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7171:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7172:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7173: 
1.202     brouard  7174:   /* Contribution to likelihood */
                   7175:   /* Plot the probability implied in the likelihood */
1.223     brouard  7176:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7177:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7178:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7179:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7180: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7181:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7182: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7183:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7184:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7185:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7186:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7187:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7188:   for (i=1; i<= nlstate ; i ++) {
                   7189:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7190:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7191:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7192:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7193:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7194:     }
                   7195:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7196:   }
                   7197:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7198:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7199:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7200:   fprintf(ficgp,"\nset out;unset log\n");
                   7201:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7202: 
1.126     brouard  7203:   strcpy(dirfileres,optionfilefiname);
                   7204:   strcpy(optfileres,"vpl");
1.223     brouard  7205:   /* 1eme*/
1.238     brouard  7206:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7207:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7208:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7209:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7210:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7211:          continue;
                   7212:        /* We are interested in selected combination by the resultline */
1.246     brouard  7213:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7214:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7215:        strcpy(gplotlabel,"(");
1.238     brouard  7216:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7217:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7218:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7219:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7220:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7221:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7222:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7223:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7224:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7225:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7226:        }
                   7227:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7228:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7229:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7230:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7231:        }
                   7232:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7233:        /* printf("\n#\n"); */
1.238     brouard  7234:        fprintf(ficgp,"\n#\n");
                   7235:        if(invalidvarcomb[k1]){
1.260     brouard  7236:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7237:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7238:          continue;
                   7239:        }
1.235     brouard  7240:       
1.241     brouard  7241:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7242:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7243:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7244:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7245:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7246:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7247:       /* k1-1 error should be nres-1*/
1.238     brouard  7248:        for (i=1; i<= nlstate ; i ++) {
                   7249:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7250:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7251:        }
1.288     brouard  7252:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7253:        for (i=1; i<= nlstate ; i ++) {
                   7254:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7255:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7256:        } 
1.260     brouard  7257:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7258:        for (i=1; i<= nlstate ; i ++) {
                   7259:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7260:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7261:        }  
1.265     brouard  7262:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7263:        
                   7264:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7265:         if(cptcoveff ==0){
1.271     brouard  7266:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7267:        }else{
                   7268:          kl=0;
                   7269:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7270:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7271:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7272:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7273:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7274:            vlv= nbcode[Tvaraff[k]][lv];
                   7275:            kl++;
                   7276:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7277:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7278:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7279:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7280:            if(k==cptcoveff){
                   7281:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7282:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7283:            }else{
                   7284:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7285:              kl++;
                   7286:            }
                   7287:          } /* end covariate */
                   7288:        } /* end if no covariate */
                   7289: 
1.296     brouard  7290:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7291:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7292:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7293:          if(cptcoveff ==0){
1.245     brouard  7294:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7295:          }else{
                   7296:            kl=0;
                   7297:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7298:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7299:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7300:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7301:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7302:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7303:              kl++;
1.238     brouard  7304:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7305:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7306:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7307:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7308:              if(k==cptcoveff){
1.245     brouard  7309:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7310:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7311:              }else{
                   7312:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7313:                kl++;
                   7314:              }
                   7315:            } /* end covariate */
                   7316:          } /* end if no covariate */
1.296     brouard  7317:          if(prevbcast == 1){
1.268     brouard  7318:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7319:            /* k1-1 error should be nres-1*/
                   7320:            for (i=1; i<= nlstate ; i ++) {
                   7321:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7322:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7323:            }
1.271     brouard  7324:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7325:            for (i=1; i<= nlstate ; i ++) {
                   7326:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7327:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7328:            } 
1.276     brouard  7329:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7330:            for (i=1; i<= nlstate ; i ++) {
                   7331:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7332:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7333:            } 
1.274     brouard  7334:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7335:          } /* end if backprojcast */
1.296     brouard  7336:        } /* end if prevbcast */
1.276     brouard  7337:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7338:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7339:       } /* nres */
1.201     brouard  7340:     } /* k1 */
                   7341:   } /* cpt */
1.235     brouard  7342: 
                   7343:   
1.126     brouard  7344:   /*2 eme*/
1.238     brouard  7345:   for (k1=1; k1<= m ; k1 ++){  
                   7346:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7347:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7348:        continue;
                   7349:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7350:       strcpy(gplotlabel,"(");
1.238     brouard  7351:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7352:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7353:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7354:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7355:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7356:        vlv= nbcode[Tvaraff[k]][lv];
                   7357:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7358:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7359:       }
1.237     brouard  7360:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7361:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7362:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7363:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7364:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7365:       }
1.264     brouard  7366:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7367:       fprintf(ficgp,"\n#\n");
1.223     brouard  7368:       if(invalidvarcomb[k1]){
                   7369:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7370:        continue;
                   7371:       }
1.219     brouard  7372:                        
1.241     brouard  7373:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7374:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7375:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7376:        if(vpopbased==0){
1.238     brouard  7377:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7378:        }else
1.238     brouard  7379:          fprintf(ficgp,"\nreplot ");
                   7380:        for (i=1; i<= nlstate+1 ; i ++) {
                   7381:          k=2*i;
1.261     brouard  7382:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7383:          for (j=1; j<= nlstate+1 ; j ++) {
                   7384:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7385:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7386:          }   
                   7387:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7388:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7389:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7390:          for (j=1; j<= nlstate+1 ; j ++) {
                   7391:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7392:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7393:          }   
                   7394:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7395:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7396:          for (j=1; j<= nlstate+1 ; j ++) {
                   7397:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7398:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7399:          }   
                   7400:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7401:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7402:        } /* state */
                   7403:       } /* vpopbased */
1.264     brouard  7404:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7405:     } /* end nres */
                   7406:   } /* k1 end 2 eme*/
                   7407:        
                   7408:        
                   7409:   /*3eme*/
                   7410:   for (k1=1; k1<= m ; k1 ++){
                   7411:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7412:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7413:        continue;
                   7414: 
                   7415:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7416:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7417:        strcpy(gplotlabel,"(");
1.238     brouard  7418:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7419:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7420:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7421:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7422:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7423:          vlv= nbcode[Tvaraff[k]][lv];
                   7424:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7425:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7426:        }
                   7427:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7428:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7429:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7430:        }       
1.264     brouard  7431:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7432:        fprintf(ficgp,"\n#\n");
                   7433:        if(invalidvarcomb[k1]){
                   7434:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7435:          continue;
                   7436:        }
                   7437:                        
                   7438:        /*       k=2+nlstate*(2*cpt-2); */
                   7439:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7440:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7441:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7442:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7443: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7444:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7445:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7446:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7447:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7448:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7449:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7450:                                
1.238     brouard  7451:        */
                   7452:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7453:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7454:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7455:                                
1.238     brouard  7456:        } 
1.261     brouard  7457:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7458:       }
1.264     brouard  7459:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7460:     } /* end nres */
                   7461:   } /* end kl 3eme */
1.126     brouard  7462:   
1.223     brouard  7463:   /* 4eme */
1.201     brouard  7464:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7465:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7466:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7467:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7468:        continue;
1.238     brouard  7469:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7470:        strcpy(gplotlabel,"(");
1.238     brouard  7471:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7472:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7473:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7474:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7475:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7476:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7477:          vlv= nbcode[Tvaraff[k]][lv];
                   7478:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7479:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7480:        }
                   7481:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7482:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7483:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7484:        }       
1.264     brouard  7485:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7486:        fprintf(ficgp,"\n#\n");
                   7487:        if(invalidvarcomb[k1]){
                   7488:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7489:          continue;
1.223     brouard  7490:        }
1.238     brouard  7491:       
1.241     brouard  7492:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7493:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7494:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7495: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7496:        k=3;
                   7497:        for (i=1; i<= nlstate ; i ++){
                   7498:          if(i==1){
                   7499:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7500:          }else{
                   7501:            fprintf(ficgp,", '' ");
                   7502:          }
                   7503:          l=(nlstate+ndeath)*(i-1)+1;
                   7504:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7505:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7506:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7507:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7508:        } /* nlstate */
1.264     brouard  7509:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7510:       } /* end cpt state*/ 
                   7511:     } /* end nres */
                   7512:   } /* end covariate k1 */  
                   7513: 
1.220     brouard  7514: /* 5eme */
1.201     brouard  7515:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7516:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7517:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7518:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7519:        continue;
1.238     brouard  7520:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7521:        strcpy(gplotlabel,"(");
1.238     brouard  7522:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7523:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7524:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7525:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7526:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7527:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7528:          vlv= nbcode[Tvaraff[k]][lv];
                   7529:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7530:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7531:        }
                   7532:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7533:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7534:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7535:        }       
1.264     brouard  7536:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7537:        fprintf(ficgp,"\n#\n");
                   7538:        if(invalidvarcomb[k1]){
                   7539:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7540:          continue;
                   7541:        }
1.227     brouard  7542:       
1.241     brouard  7543:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7544:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7545:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7546: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7547:        k=3;
                   7548:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7549:          if(j==1)
                   7550:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7551:          else
                   7552:            fprintf(ficgp,", '' ");
                   7553:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7554:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7555:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7556:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7557:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7558:        } /* nlstate */
                   7559:        fprintf(ficgp,", '' ");
                   7560:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7561:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7562:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7563:          if(j < nlstate)
                   7564:            fprintf(ficgp,"$%d +",k+l);
                   7565:          else
                   7566:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7567:        }
1.264     brouard  7568:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7569:       } /* end cpt state*/ 
                   7570:     } /* end covariate */  
                   7571:   } /* end nres */
1.227     brouard  7572:   
1.220     brouard  7573: /* 6eme */
1.202     brouard  7574:   /* CV preval stable (period) for each covariate */
1.237     brouard  7575:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7576:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7577:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7578:       continue;
1.255     brouard  7579:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7580:       strcpy(gplotlabel,"(");      
1.288     brouard  7581:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7582:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7583:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7584:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7585:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7586:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7587:        vlv= nbcode[Tvaraff[k]][lv];
                   7588:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7589:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7590:       }
1.237     brouard  7591:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7592:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7593:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7594:       }        
1.264     brouard  7595:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7596:       fprintf(ficgp,"\n#\n");
1.223     brouard  7597:       if(invalidvarcomb[k1]){
1.227     brouard  7598:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7599:        continue;
1.223     brouard  7600:       }
1.227     brouard  7601:       
1.241     brouard  7602:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7603:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7604:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7605: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7606:       k=3; /* Offset */
1.255     brouard  7607:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7608:        if(i==1)
                   7609:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7610:        else
                   7611:          fprintf(ficgp,", '' ");
1.255     brouard  7612:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7613:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7614:        for (j=2; j<= nlstate ; j ++)
                   7615:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7616:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7617:       } /* nlstate */
1.264     brouard  7618:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7619:     } /* end cpt state*/ 
                   7620:   } /* end covariate */  
1.227     brouard  7621:   
                   7622:   
1.220     brouard  7623: /* 7eme */
1.296     brouard  7624:   if(prevbcast == 1){
1.288     brouard  7625:     /* CV backward prevalence  for each covariate */
1.237     brouard  7626:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7627:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7628:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7629:        continue;
1.268     brouard  7630:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7631:        strcpy(gplotlabel,"(");      
1.288     brouard  7632:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7633:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7634:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7635:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7636:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7637:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7638:          vlv= nbcode[Tvaraff[k]][lv];
                   7639:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7640:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7641:        }
1.237     brouard  7642:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7643:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7644:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7645:        }       
1.264     brouard  7646:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7647:        fprintf(ficgp,"\n#\n");
                   7648:        if(invalidvarcomb[k1]){
                   7649:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7650:          continue;
                   7651:        }
                   7652:        
1.241     brouard  7653:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7654:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7655:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7656: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7657:        k=3; /* Offset */
1.268     brouard  7658:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7659:          if(i==1)
                   7660:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7661:          else
                   7662:            fprintf(ficgp,", '' ");
                   7663:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7664:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7665:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7666:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7667:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7668:          /* for (j=2; j<= nlstate ; j ++) */
                   7669:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7670:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7671:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7672:        } /* nlstate */
1.264     brouard  7673:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7674:       } /* end cpt state*/ 
                   7675:     } /* end covariate */  
1.296     brouard  7676:   } /* End if prevbcast */
1.218     brouard  7677:   
1.223     brouard  7678:   /* 8eme */
1.218     brouard  7679:   if(prevfcast==1){
1.288     brouard  7680:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7681:     
1.237     brouard  7682:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7683:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7684:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7685:        continue;
1.211     brouard  7686:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7687:        strcpy(gplotlabel,"(");      
1.288     brouard  7688:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7689:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7690:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7691:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7692:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7693:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7694:          vlv= nbcode[Tvaraff[k]][lv];
                   7695:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7696:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7697:        }
1.237     brouard  7698:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7699:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7700:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7701:        }       
1.264     brouard  7702:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7703:        fprintf(ficgp,"\n#\n");
                   7704:        if(invalidvarcomb[k1]){
                   7705:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7706:          continue;
                   7707:        }
                   7708:        
                   7709:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7710:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7711:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7712:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7713: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7714: 
                   7715:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7716:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7717:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7718:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7719:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7720:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7721:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7722:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7723:          if(i==istart){
1.227     brouard  7724:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7725:          }else{
                   7726:            fprintf(ficgp,",\\\n '' ");
                   7727:          }
                   7728:          if(cptcoveff ==0){ /* No covariate */
                   7729:            ioffset=2; /* Age is in 2 */
                   7730:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7731:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7732:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7733:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7734:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7735:            if(i==nlstate+1){
1.270     brouard  7736:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7737:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7738:              fprintf(ficgp,",\\\n '' ");
                   7739:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7740:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7741:                     offyear,                           \
1.268     brouard  7742:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7743:            }else
1.227     brouard  7744:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7745:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7746:          }else{ /* more than 2 covariates */
1.270     brouard  7747:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7748:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7749:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7750:            iyearc=ioffset-1;
                   7751:            iagec=ioffset;
1.227     brouard  7752:            fprintf(ficgp," u %d:(",ioffset); 
                   7753:            kl=0;
                   7754:            strcpy(gplotcondition,"(");
                   7755:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7756:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7757:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7758:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7759:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7760:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7761:              kl++;
                   7762:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7763:              kl++;
                   7764:              if(k <cptcoveff && cptcoveff>1)
                   7765:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7766:            }
                   7767:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7768:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7769:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7770:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7771:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7772:            if(i==nlstate+1){
1.270     brouard  7773:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7774:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7775:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7776:              fprintf(ficgp," u %d:(",iagec); 
                   7777:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7778:                      iyearc, iagec, offyear,                           \
                   7779:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7780: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7781:            }else{
                   7782:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7783:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7784:            }
                   7785:          } /* end if covariate */
                   7786:        } /* nlstate */
1.264     brouard  7787:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7788:       } /* end cpt state*/
                   7789:     } /* end covariate */
                   7790:   } /* End if prevfcast */
1.227     brouard  7791:   
1.296     brouard  7792:   if(prevbcast==1){
1.268     brouard  7793:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7794:     
                   7795:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7796:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7797:       if(m != 1 && TKresult[nres]!= k1)
                   7798:        continue;
                   7799:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7800:        strcpy(gplotlabel,"(");      
                   7801:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7802:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7803:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7804:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7805:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7806:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7807:          vlv= nbcode[Tvaraff[k]][lv];
                   7808:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7809:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7810:        }
                   7811:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7812:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7813:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7814:        }       
                   7815:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7816:        fprintf(ficgp,"\n#\n");
                   7817:        if(invalidvarcomb[k1]){
                   7818:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7819:          continue;
                   7820:        }
                   7821:        
                   7822:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7823:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7824:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7825:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7826: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7827: 
                   7828:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7829:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7830:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7831:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7832:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7833:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7834:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7835:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7836:          if(i==istart){
                   7837:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7838:          }else{
                   7839:            fprintf(ficgp,",\\\n '' ");
                   7840:          }
                   7841:          if(cptcoveff ==0){ /* No covariate */
                   7842:            ioffset=2; /* Age is in 2 */
                   7843:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7844:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7845:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7846:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7847:            fprintf(ficgp," u %d:(", ioffset); 
                   7848:            if(i==nlstate+1){
1.270     brouard  7849:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7850:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7851:              fprintf(ficgp,",\\\n '' ");
                   7852:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7853:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7854:                     offbyear,                          \
                   7855:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7856:            }else
                   7857:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7858:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7859:          }else{ /* more than 2 covariates */
1.270     brouard  7860:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7861:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7862:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7863:            iyearc=ioffset-1;
                   7864:            iagec=ioffset;
1.268     brouard  7865:            fprintf(ficgp," u %d:(",ioffset); 
                   7866:            kl=0;
                   7867:            strcpy(gplotcondition,"(");
                   7868:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7869:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7870:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7871:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7872:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7873:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7874:              kl++;
                   7875:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7876:              kl++;
                   7877:              if(k <cptcoveff && cptcoveff>1)
                   7878:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7879:            }
                   7880:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7881:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7882:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7883:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7884:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7885:            if(i==nlstate+1){
1.270     brouard  7886:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7887:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7888:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7889:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7890:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7891:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7892:                      iyearc,iagec,offbyear,                            \
                   7893:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7894: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7895:            }else{
                   7896:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7897:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7898:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7899:            }
                   7900:          } /* end if covariate */
                   7901:        } /* nlstate */
                   7902:        fprintf(ficgp,"\nset out; unset label;\n");
                   7903:       } /* end cpt state*/
                   7904:     } /* end covariate */
1.296     brouard  7905:   } /* End if prevbcast */
1.268     brouard  7906:   
1.227     brouard  7907:   
1.238     brouard  7908:   /* 9eme writing MLE parameters */
                   7909:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7910:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7911:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7912:     for(k=1; k <=(nlstate+ndeath); k++){
                   7913:       if (k != i) {
1.227     brouard  7914:        fprintf(ficgp,"#   current state %d\n",k);
                   7915:        for(j=1; j <=ncovmodel; j++){
                   7916:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7917:          jk++; 
                   7918:        }
                   7919:        fprintf(ficgp,"\n");
1.126     brouard  7920:       }
                   7921:     }
1.223     brouard  7922:   }
1.187     brouard  7923:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7924:   
1.145     brouard  7925:   /*goto avoid;*/
1.238     brouard  7926:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7927:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7928:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7929:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7930:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7931:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7932:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7933:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7934:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7935:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7936:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7937:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7938:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7939:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7940:   fprintf(ficgp,"#\n");
1.223     brouard  7941:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7942:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7943:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7944:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7945:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7946:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7947:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7948:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7949:        continue;
1.264     brouard  7950:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7951:       strcpy(gplotlabel,"(");
1.276     brouard  7952:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7953:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7954:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7955:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7956:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7957:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7958:        vlv= nbcode[Tvaraff[k]][lv];
                   7959:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7960:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7961:       }
1.237     brouard  7962:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7963:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7964:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7965:       }        
1.264     brouard  7966:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7967:       fprintf(ficgp,"\n#\n");
1.264     brouard  7968:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7969:       fprintf(ficgp,"\nset key outside ");
                   7970:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7971:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7972:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7973:       if (ng==1){
                   7974:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7975:        fprintf(ficgp,"\nunset log y");
                   7976:       }else if (ng==2){
                   7977:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7978:        fprintf(ficgp,"\nset log y");
                   7979:       }else if (ng==3){
                   7980:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7981:        fprintf(ficgp,"\nset log y");
                   7982:       }else
                   7983:        fprintf(ficgp,"\nunset title ");
                   7984:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7985:       i=1;
                   7986:       for(k2=1; k2<=nlstate; k2++) {
                   7987:        k3=i;
                   7988:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7989:          if (k != k2){
                   7990:            switch( ng) {
                   7991:            case 1:
                   7992:              if(nagesqr==0)
                   7993:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7994:              else /* nagesqr =1 */
                   7995:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7996:              break;
                   7997:            case 2: /* ng=2 */
                   7998:              if(nagesqr==0)
                   7999:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8000:              else /* nagesqr =1 */
                   8001:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8002:              break;
                   8003:            case 3:
                   8004:              if(nagesqr==0)
                   8005:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8006:              else /* nagesqr =1 */
                   8007:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8008:              break;
                   8009:            }
                   8010:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8011:            ijp=1; /* product no age */
                   8012:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8013:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8014:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8015:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8016:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8017:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8018:                    if(DummyV[j]==0){
                   8019:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8020:                    }else{ /* quantitative */
                   8021:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8022:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8023:                    }
                   8024:                    ij++;
1.237     brouard  8025:                  }
1.268     brouard  8026:                } 
                   8027:              }else if(cptcovprod >0){
                   8028:                if(j==Tprod[ijp]) { /* */ 
                   8029:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8030:                  if(ijp <=cptcovprod) { /* Product */
                   8031:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8032:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8033:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8034:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8035:                      }else{ /* Vn is dummy and Vm is quanti */
                   8036:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8037:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8038:                      }
                   8039:                    }else{ /* Vn*Vm Vn is quanti */
                   8040:                      if(DummyV[Tvard[ijp][2]]==0){
                   8041:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8042:                      }else{ /* Both quanti */
                   8043:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8044:                      }
1.237     brouard  8045:                    }
1.268     brouard  8046:                    ijp++;
1.237     brouard  8047:                  }
1.268     brouard  8048:                } /* end Tprod */
1.237     brouard  8049:              } else{  /* simple covariate */
1.264     brouard  8050:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8051:                if(Dummy[j]==0){
                   8052:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8053:                }else{ /* quantitative */
                   8054:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8055:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8056:                }
1.237     brouard  8057:              } /* end simple */
                   8058:            } /* end j */
1.223     brouard  8059:          }else{
                   8060:            i=i-ncovmodel;
                   8061:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8062:              fprintf(ficgp," (1.");
                   8063:          }
1.227     brouard  8064:          
1.223     brouard  8065:          if(ng != 1){
                   8066:            fprintf(ficgp,")/(1");
1.227     brouard  8067:            
1.264     brouard  8068:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8069:              if(nagesqr==0)
1.264     brouard  8070:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8071:              else /* nagesqr =1 */
1.264     brouard  8072:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8073:               
1.223     brouard  8074:              ij=1;
                   8075:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8076:                 if(cptcovage >0){ 
                   8077:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8078:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8079:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8080:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8081:                       ij++;
                   8082:                     }
                   8083:                   }
                   8084:                 }else
                   8085:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8086:              }
                   8087:              fprintf(ficgp,")");
                   8088:            }
                   8089:            fprintf(ficgp,")");
                   8090:            if(ng ==2)
1.276     brouard  8091:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8092:            else /* ng= 3 */
1.276     brouard  8093:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8094:          }else{ /* end ng <> 1 */
                   8095:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8096:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8097:          }
                   8098:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8099:            fprintf(ficgp,",");
                   8100:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8101:            fprintf(ficgp,",");
                   8102:          i=i+ncovmodel;
                   8103:        } /* end k */
                   8104:       } /* end k2 */
1.276     brouard  8105:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8106:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8107:     } /* end k1 */
1.223     brouard  8108:   } /* end ng */
                   8109:   /* avoid: */
                   8110:   fflush(ficgp); 
1.126     brouard  8111: }  /* end gnuplot */
                   8112: 
                   8113: 
                   8114: /*************** Moving average **************/
1.219     brouard  8115: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8116:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8117:    
1.222     brouard  8118:    int i, cpt, cptcod;
                   8119:    int modcovmax =1;
                   8120:    int mobilavrange, mob;
                   8121:    int iage=0;
1.288     brouard  8122:    int firstA1=0, firstA2=0;
1.222     brouard  8123: 
1.266     brouard  8124:    double sum=0., sumr=0.;
1.222     brouard  8125:    double age;
1.266     brouard  8126:    double *sumnewp, *sumnewm, *sumnewmr;
                   8127:    double *agemingood, *agemaxgood; 
                   8128:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8129:   
                   8130:   
1.278     brouard  8131:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8132:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8133: 
                   8134:    sumnewp = vector(1,ncovcombmax);
                   8135:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8136:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8137:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8138:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8139:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8140:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8141: 
                   8142:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8143:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8144:      sumnewp[cptcod]=0.;
1.266     brouard  8145:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8146:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8147:    }
                   8148:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8149:   
1.266     brouard  8150:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8151:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8152:      else mobilavrange=mobilav;
                   8153:      for (age=bage; age<=fage; age++)
                   8154:        for (i=1; i<=nlstate;i++)
                   8155:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8156:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8157:      /* We keep the original values on the extreme ages bage, fage and for 
                   8158:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8159:        we use a 5 terms etc. until the borders are no more concerned. 
                   8160:      */ 
                   8161:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8162:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8163:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8164:           sumnewm[cptcod]=0.;
                   8165:           for (i=1; i<=nlstate;i++){
1.222     brouard  8166:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8167:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8168:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8169:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8170:             }
                   8171:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8172:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8173:           } /* end i */
                   8174:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8175:         } /* end cptcod */
1.222     brouard  8176:        }/* end age */
                   8177:      }/* end mob */
1.266     brouard  8178:    }else{
                   8179:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8180:      return -1;
1.266     brouard  8181:    }
                   8182: 
                   8183:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8184:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8185:      if(invalidvarcomb[cptcod]){
                   8186:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8187:        continue;
                   8188:      }
1.219     brouard  8189: 
1.266     brouard  8190:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8191:        sumnewm[cptcod]=0.;
                   8192:        sumnewmr[cptcod]=0.;
                   8193:        for (i=1; i<=nlstate;i++){
                   8194:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8195:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8196:        }
                   8197:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8198:         agemingoodr[cptcod]=age;
                   8199:        }
                   8200:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8201:           agemingood[cptcod]=age;
                   8202:        }
                   8203:      } /* age */
                   8204:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8205:        sumnewm[cptcod]=0.;
1.266     brouard  8206:        sumnewmr[cptcod]=0.;
1.222     brouard  8207:        for (i=1; i<=nlstate;i++){
                   8208:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8209:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8210:        }
                   8211:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8212:         agemaxgoodr[cptcod]=age;
1.222     brouard  8213:        }
                   8214:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8215:         agemaxgood[cptcod]=age;
                   8216:        }
                   8217:      } /* age */
                   8218:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8219:      /* but they will change */
1.288     brouard  8220:      firstA1=0;firstA2=0;
1.266     brouard  8221:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8222:        sumnewm[cptcod]=0.;
                   8223:        sumnewmr[cptcod]=0.;
                   8224:        for (i=1; i<=nlstate;i++){
                   8225:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8226:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8227:        }
                   8228:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8229:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8230:           agemaxgoodr[cptcod]=age;  /* age min */
                   8231:           for (i=1; i<=nlstate;i++)
                   8232:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8233:         }else{ /* bad we change the value with the values of good ages */
                   8234:           for (i=1; i<=nlstate;i++){
                   8235:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8236:           } /* i */
                   8237:         } /* end bad */
                   8238:        }else{
                   8239:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8240:           agemaxgood[cptcod]=age;
                   8241:         }else{ /* bad we change the value with the values of good ages */
                   8242:           for (i=1; i<=nlstate;i++){
                   8243:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8244:           } /* i */
                   8245:         } /* end bad */
                   8246:        }/* end else */
                   8247:        sum=0.;sumr=0.;
                   8248:        for (i=1; i<=nlstate;i++){
                   8249:         sum+=mobaverage[(int)age][i][cptcod];
                   8250:         sumr+=probs[(int)age][i][cptcod];
                   8251:        }
                   8252:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8253:         if(!firstA1){
                   8254:           firstA1=1;
                   8255:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8256:         }
                   8257:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8258:        } /* end bad */
                   8259:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8260:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8261:         if(!firstA2){
                   8262:           firstA2=1;
                   8263:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8264:         }
                   8265:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8266:        } /* end bad */
                   8267:      }/* age */
1.266     brouard  8268: 
                   8269:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8270:        sumnewm[cptcod]=0.;
1.266     brouard  8271:        sumnewmr[cptcod]=0.;
1.222     brouard  8272:        for (i=1; i<=nlstate;i++){
                   8273:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8274:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8275:        } 
                   8276:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8277:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8278:           agemingoodr[cptcod]=age;
                   8279:           for (i=1; i<=nlstate;i++)
                   8280:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8281:         }else{ /* bad we change the value with the values of good ages */
                   8282:           for (i=1; i<=nlstate;i++){
                   8283:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8284:           } /* i */
                   8285:         } /* end bad */
                   8286:        }else{
                   8287:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8288:           agemingood[cptcod]=age;
                   8289:         }else{ /* bad */
                   8290:           for (i=1; i<=nlstate;i++){
                   8291:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8292:           } /* i */
                   8293:         } /* end bad */
                   8294:        }/* end else */
                   8295:        sum=0.;sumr=0.;
                   8296:        for (i=1; i<=nlstate;i++){
                   8297:         sum+=mobaverage[(int)age][i][cptcod];
                   8298:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8299:        }
1.266     brouard  8300:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8301:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8302:        } /* end bad */
                   8303:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8304:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8305:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8306:        } /* end bad */
                   8307:      }/* age */
1.266     brouard  8308: 
1.222     brouard  8309:                
                   8310:      for (age=bage; age<=fage; age++){
1.235     brouard  8311:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8312:        sumnewp[cptcod]=0.;
                   8313:        sumnewm[cptcod]=0.;
                   8314:        for (i=1; i<=nlstate;i++){
                   8315:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8316:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8317:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8318:        }
                   8319:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8320:      }
                   8321:      /* printf("\n"); */
                   8322:      /* } */
1.266     brouard  8323: 
1.222     brouard  8324:      /* brutal averaging */
1.266     brouard  8325:      /* for (i=1; i<=nlstate;i++){ */
                   8326:      /*   for (age=1; age<=bage; age++){ */
                   8327:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8328:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8329:      /*   }     */
                   8330:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8331:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8332:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8333:      /*   } */
                   8334:      /* } /\* end i status *\/ */
                   8335:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8336:      /*   for (age=1; age<=AGESUP; age++){ */
                   8337:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8338:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8339:      /*   } */
                   8340:      /* } */
1.222     brouard  8341:    }/* end cptcod */
1.266     brouard  8342:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8343:    free_vector(agemaxgood,1, ncovcombmax);
                   8344:    free_vector(agemingood,1, ncovcombmax);
                   8345:    free_vector(agemingoodr,1, ncovcombmax);
                   8346:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8347:    free_vector(sumnewm,1, ncovcombmax);
                   8348:    free_vector(sumnewp,1, ncovcombmax);
                   8349:    return 0;
                   8350:  }/* End movingaverage */
1.218     brouard  8351:  
1.126     brouard  8352: 
1.296     brouard  8353:  
1.126     brouard  8354: /************** Forecasting ******************/
1.296     brouard  8355: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8356: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8357:   /* dateintemean, mean date of interviews
                   8358:      dateprojd, year, month, day of starting projection 
                   8359:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8360:      agemin, agemax range of age
                   8361:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8362:   */
1.296     brouard  8363:   /* double anprojd, mprojd, jprojd; */
                   8364:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8365:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8366:   double agec; /* generic age */
1.296     brouard  8367:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8368:   double *popeffectif,*popcount;
                   8369:   double ***p3mat;
1.218     brouard  8370:   /* double ***mobaverage; */
1.126     brouard  8371:   char fileresf[FILENAMELENGTH];
                   8372: 
                   8373:   agelim=AGESUP;
1.211     brouard  8374:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8375:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8376:      We still use firstpass and lastpass as another selection.
                   8377:   */
1.214     brouard  8378:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8379:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8380:  
1.201     brouard  8381:   strcpy(fileresf,"F_"); 
                   8382:   strcat(fileresf,fileresu);
1.126     brouard  8383:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8384:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8385:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8386:   }
1.235     brouard  8387:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8388:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8389: 
1.225     brouard  8390:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8391: 
                   8392: 
                   8393:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8394:   if (stepm<=12) stepsize=1;
                   8395:   if(estepm < stepm){
                   8396:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8397:   }
1.270     brouard  8398:   else{
                   8399:     hstepm=estepm;   
                   8400:   }
                   8401:   if(estepm > stepm){ /* Yes every two year */
                   8402:     stepsize=2;
                   8403:   }
1.296     brouard  8404:   hstepm=hstepm/stepm;
1.126     brouard  8405: 
1.296     brouard  8406:   
                   8407:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8408:   /*                              fractional in yp1 *\/ */
                   8409:   /* aintmean=yp; */
                   8410:   /* yp2=modf((yp1*12),&yp); */
                   8411:   /* mintmean=yp; */
                   8412:   /* yp1=modf((yp2*30.5),&yp); */
                   8413:   /* jintmean=yp; */
                   8414:   /* if(jintmean==0) jintmean=1; */
                   8415:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8416: 
1.296     brouard  8417: 
                   8418:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8419:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8420:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8421:   i1=pow(2,cptcoveff);
1.126     brouard  8422:   if (cptcovn < 1){i1=1;}
                   8423:   
1.296     brouard  8424:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8425:   
                   8426:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8427:   
1.126     brouard  8428: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8429:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8430:   for(k=1; k<=i1;k++){
1.253     brouard  8431:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8432:       continue;
1.227     brouard  8433:     if(invalidvarcomb[k]){
                   8434:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8435:       continue;
                   8436:     }
                   8437:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8438:     for(j=1;j<=cptcoveff;j++) {
                   8439:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8440:     }
1.235     brouard  8441:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8442:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8443:     }
1.227     brouard  8444:     fprintf(ficresf," yearproj age");
                   8445:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8446:       for(i=1; i<=nlstate;i++)               
                   8447:        fprintf(ficresf," p%d%d",i,j);
                   8448:       fprintf(ficresf," wp.%d",j);
                   8449:     }
1.296     brouard  8450:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8451:       fprintf(ficresf,"\n");
1.296     brouard  8452:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8453:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8454:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8455:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8456:        nhstepm = nhstepm/hstepm; 
                   8457:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8458:        oldm=oldms;savm=savms;
1.268     brouard  8459:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8460:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8461:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8462:        for (h=0; h<=nhstepm; h++){
                   8463:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8464:            break;
                   8465:          }
                   8466:        }
                   8467:        fprintf(ficresf,"\n");
                   8468:        for(j=1;j<=cptcoveff;j++) 
                   8469:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8470:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8471:        
                   8472:        for(j=1; j<=nlstate+ndeath;j++) {
                   8473:          ppij=0.;
                   8474:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8475:            if (mobilav>=1)
                   8476:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8477:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8478:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8479:            }
1.268     brouard  8480:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8481:          } /* end i */
                   8482:          fprintf(ficresf," %.3f", ppij);
                   8483:        }/* end j */
1.227     brouard  8484:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8485:       } /* end agec */
1.266     brouard  8486:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8487:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8488:     } /* end yearp */
                   8489:   } /* end  k */
1.219     brouard  8490:        
1.126     brouard  8491:   fclose(ficresf);
1.215     brouard  8492:   printf("End of Computing forecasting \n");
                   8493:   fprintf(ficlog,"End of Computing forecasting\n");
                   8494: 
1.126     brouard  8495: }
                   8496: 
1.269     brouard  8497: /************** Back Forecasting ******************/
1.296     brouard  8498:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8499:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8500:   /* back1, year, month, day of starting backprojection
1.267     brouard  8501:      agemin, agemax range of age
                   8502:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8503:      anback2 year of end of backprojection (same day and month as back1).
                   8504:      prevacurrent and prev are prevalences.
1.267     brouard  8505:   */
                   8506:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8507:   double agec; /* generic age */
1.302   ! brouard  8508:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8509:   double *popeffectif,*popcount;
                   8510:   double ***p3mat;
                   8511:   /* double ***mobaverage; */
                   8512:   char fileresfb[FILENAMELENGTH];
                   8513:  
1.268     brouard  8514:   agelim=AGEINF;
1.267     brouard  8515:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8516:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8517:      We still use firstpass and lastpass as another selection.
                   8518:   */
                   8519:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8520:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8521: 
                   8522:   /*Do we need to compute prevalence again?*/
                   8523: 
                   8524:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8525:   
                   8526:   strcpy(fileresfb,"FB_");
                   8527:   strcat(fileresfb,fileresu);
                   8528:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8529:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8530:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8531:   }
                   8532:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8533:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8534:   
                   8535:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8536:   
                   8537:    
                   8538:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8539:   if (stepm<=12) stepsize=1;
                   8540:   if(estepm < stepm){
                   8541:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8542:   }
1.270     brouard  8543:   else{
                   8544:     hstepm=estepm;   
                   8545:   }
                   8546:   if(estepm >= stepm){ /* Yes every two year */
                   8547:     stepsize=2;
                   8548:   }
1.267     brouard  8549:   
                   8550:   hstepm=hstepm/stepm;
1.296     brouard  8551:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8552:   /*                              fractional in yp1 *\/ */
                   8553:   /* aintmean=yp; */
                   8554:   /* yp2=modf((yp1*12),&yp); */
                   8555:   /* mintmean=yp; */
                   8556:   /* yp1=modf((yp2*30.5),&yp); */
                   8557:   /* jintmean=yp; */
                   8558:   /* if(jintmean==0) jintmean=1; */
                   8559:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8560:   
                   8561:   i1=pow(2,cptcoveff);
                   8562:   if (cptcovn < 1){i1=1;}
                   8563:   
1.296     brouard  8564:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8565:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8566:   
                   8567:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8568:   
                   8569:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8570:   for(k=1; k<=i1;k++){
                   8571:     if(i1 != 1 && TKresult[nres]!= k)
                   8572:       continue;
                   8573:     if(invalidvarcomb[k]){
                   8574:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8575:       continue;
                   8576:     }
1.268     brouard  8577:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8578:     for(j=1;j<=cptcoveff;j++) {
                   8579:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8580:     }
                   8581:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8582:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8583:     }
                   8584:     fprintf(ficresfb," yearbproj age");
                   8585:     for(j=1; j<=nlstate+ndeath;j++){
                   8586:       for(i=1; i<=nlstate;i++)
1.268     brouard  8587:        fprintf(ficresfb," b%d%d",i,j);
                   8588:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8589:     }
1.296     brouard  8590:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8591:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8592:       fprintf(ficresfb,"\n");
1.296     brouard  8593:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8594:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8595:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8596:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8597:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8598:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8599:        nhstepm = nhstepm/hstepm;
                   8600:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8601:        oldm=oldms;savm=savms;
1.268     brouard  8602:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8603:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8604:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8605:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8606:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8607:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8608:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8609:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8610:            break;
                   8611:          }
                   8612:        }
                   8613:        fprintf(ficresfb,"\n");
                   8614:        for(j=1;j<=cptcoveff;j++)
                   8615:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8616:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8617:        for(i=1; i<=nlstate+ndeath;i++) {
                   8618:          ppij=0.;ppi=0.;
                   8619:          for(j=1; j<=nlstate;j++) {
                   8620:            /* if (mobilav==1) */
1.269     brouard  8621:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8622:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8623:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8624:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8625:              /* else { */
                   8626:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8627:              /* } */
1.268     brouard  8628:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8629:          } /* end j */
                   8630:          if(ppi <0.99){
                   8631:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8632:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8633:          }
                   8634:          fprintf(ficresfb," %.3f", ppij);
                   8635:        }/* end j */
1.267     brouard  8636:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8637:       } /* end agec */
                   8638:     } /* end yearp */
                   8639:   } /* end k */
1.217     brouard  8640:   
1.267     brouard  8641:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8642:   
1.267     brouard  8643:   fclose(ficresfb);
                   8644:   printf("End of Computing Back forecasting \n");
                   8645:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8646:        
1.267     brouard  8647: }
1.217     brouard  8648: 
1.269     brouard  8649: /* Variance of prevalence limit: varprlim */
                   8650:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8651:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8652:  
                   8653:    char fileresvpl[FILENAMELENGTH];  
                   8654:    FILE *ficresvpl;
                   8655:    double **oldm, **savm;
                   8656:    double **varpl; /* Variances of prevalence limits by age */   
                   8657:    int i1, k, nres, j ;
                   8658:    
                   8659:     strcpy(fileresvpl,"VPL_");
                   8660:     strcat(fileresvpl,fileresu);
                   8661:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8662:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8663:       exit(0);
                   8664:     }
1.288     brouard  8665:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8666:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8667:     
                   8668:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8669:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8670:     
                   8671:     i1=pow(2,cptcoveff);
                   8672:     if (cptcovn < 1){i1=1;}
                   8673: 
                   8674:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8675:     for(k=1; k<=i1;k++){
                   8676:       if(i1 != 1 && TKresult[nres]!= k)
                   8677:        continue;
                   8678:       fprintf(ficresvpl,"\n#****** ");
                   8679:       printf("\n#****** ");
                   8680:       fprintf(ficlog,"\n#****** ");
                   8681:       for(j=1;j<=cptcoveff;j++) {
                   8682:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8683:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8684:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8685:       }
                   8686:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8687:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8688:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8689:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8690:       }        
                   8691:       fprintf(ficresvpl,"******\n");
                   8692:       printf("******\n");
                   8693:       fprintf(ficlog,"******\n");
                   8694:       
                   8695:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8696:       oldm=oldms;savm=savms;
                   8697:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8698:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8699:       /*}*/
                   8700:     }
                   8701:     
                   8702:     fclose(ficresvpl);
1.288     brouard  8703:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8704:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8705: 
                   8706:  }
                   8707: /* Variance of back prevalence: varbprlim */
                   8708:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8709:       /*------- Variance of back (stable) prevalence------*/
                   8710: 
                   8711:    char fileresvbl[FILENAMELENGTH];  
                   8712:    FILE  *ficresvbl;
                   8713: 
                   8714:    double **oldm, **savm;
                   8715:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8716:    int i1, k, nres, j ;
                   8717: 
                   8718:    strcpy(fileresvbl,"VBL_");
                   8719:    strcat(fileresvbl,fileresu);
                   8720:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8721:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8722:      exit(0);
                   8723:    }
                   8724:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8725:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8726:    
                   8727:    
                   8728:    i1=pow(2,cptcoveff);
                   8729:    if (cptcovn < 1){i1=1;}
                   8730:    
                   8731:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8732:      for(k=1; k<=i1;k++){
                   8733:        if(i1 != 1 && TKresult[nres]!= k)
                   8734:         continue;
                   8735:        fprintf(ficresvbl,"\n#****** ");
                   8736:        printf("\n#****** ");
                   8737:        fprintf(ficlog,"\n#****** ");
                   8738:        for(j=1;j<=cptcoveff;j++) {
                   8739:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8740:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8741:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8742:        }
                   8743:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8744:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8745:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8746:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8747:        }
                   8748:        fprintf(ficresvbl,"******\n");
                   8749:        printf("******\n");
                   8750:        fprintf(ficlog,"******\n");
                   8751:        
                   8752:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8753:        oldm=oldms;savm=savms;
                   8754:        
                   8755:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8756:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8757:        /*}*/
                   8758:      }
                   8759:    
                   8760:    fclose(ficresvbl);
                   8761:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8762:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8763: 
                   8764:  } /* End of varbprlim */
                   8765: 
1.126     brouard  8766: /************** Forecasting *****not tested NB*************/
1.227     brouard  8767: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8768:   
1.227     brouard  8769: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8770: /*   int *popage; */
                   8771: /*   double calagedatem, agelim, kk1, kk2; */
                   8772: /*   double *popeffectif,*popcount; */
                   8773: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8774: /*   /\* double ***mobaverage; *\/ */
                   8775: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8776: 
1.227     brouard  8777: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8778: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8779: /*   agelim=AGESUP; */
                   8780: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8781:   
1.227     brouard  8782: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8783:   
                   8784:   
1.227     brouard  8785: /*   strcpy(filerespop,"POP_");  */
                   8786: /*   strcat(filerespop,fileresu); */
                   8787: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8788: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8789: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8790: /*   } */
                   8791: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8792: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8793: 
1.227     brouard  8794: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8795: 
1.227     brouard  8796: /*   /\* if (mobilav!=0) { *\/ */
                   8797: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8798: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8799: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8800: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8801: /*   /\*   } *\/ */
                   8802: /*   /\* } *\/ */
1.126     brouard  8803: 
1.227     brouard  8804: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8805: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8806:   
1.227     brouard  8807: /*   agelim=AGESUP; */
1.126     brouard  8808:   
1.227     brouard  8809: /*   hstepm=1; */
                   8810: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8811:        
1.227     brouard  8812: /*   if (popforecast==1) { */
                   8813: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8814: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8815: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8816: /*     }  */
                   8817: /*     popage=ivector(0,AGESUP); */
                   8818: /*     popeffectif=vector(0,AGESUP); */
                   8819: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8820:     
1.227     brouard  8821: /*     i=1;    */
                   8822: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8823:     
1.227     brouard  8824: /*     imx=i; */
                   8825: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8826: /*   } */
1.218     brouard  8827:   
1.227     brouard  8828: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8829: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8830: /*       k=k+1; */
                   8831: /*       fprintf(ficrespop,"\n#******"); */
                   8832: /*       for(j=1;j<=cptcoveff;j++) { */
                   8833: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8834: /*       } */
                   8835: /*       fprintf(ficrespop,"******\n"); */
                   8836: /*       fprintf(ficrespop,"# Age"); */
                   8837: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8838: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8839:       
1.227     brouard  8840: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8841: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8842:        
1.227     brouard  8843: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8844: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8845: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8846:          
1.227     brouard  8847: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8848: /*       oldm=oldms;savm=savms; */
                   8849: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8850:          
1.227     brouard  8851: /*       for (h=0; h<=nhstepm; h++){ */
                   8852: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8853: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8854: /*         }  */
                   8855: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8856: /*           kk1=0.;kk2=0; */
                   8857: /*           for(i=1; i<=nlstate;i++) {               */
                   8858: /*             if (mobilav==1)  */
                   8859: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8860: /*             else { */
                   8861: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8862: /*             } */
                   8863: /*           } */
                   8864: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8865: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8866: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8867: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8868: /*           } */
                   8869: /*         } */
                   8870: /*         for(i=1; i<=nlstate;i++){ */
                   8871: /*           kk1=0.; */
                   8872: /*           for(j=1; j<=nlstate;j++){ */
                   8873: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8874: /*           } */
                   8875: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8876: /*         } */
1.218     brouard  8877:            
1.227     brouard  8878: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8879: /*           for(j=1; j<=nlstate;j++)  */
                   8880: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8881: /*       } */
                   8882: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8883: /*     } */
                   8884: /*       } */
1.218     brouard  8885:       
1.227     brouard  8886: /*       /\******\/ */
1.218     brouard  8887:       
1.227     brouard  8888: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8889: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8890: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8891: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8892: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8893:          
1.227     brouard  8894: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8895: /*       oldm=oldms;savm=savms; */
                   8896: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8897: /*       for (h=0; h<=nhstepm; h++){ */
                   8898: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8899: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8900: /*         }  */
                   8901: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8902: /*           kk1=0.;kk2=0; */
                   8903: /*           for(i=1; i<=nlstate;i++) {               */
                   8904: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8905: /*           } */
                   8906: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8907: /*         } */
                   8908: /*       } */
                   8909: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8910: /*     } */
                   8911: /*       } */
                   8912: /*     }  */
                   8913: /*   } */
1.218     brouard  8914:   
1.227     brouard  8915: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8916:   
1.227     brouard  8917: /*   if (popforecast==1) { */
                   8918: /*     free_ivector(popage,0,AGESUP); */
                   8919: /*     free_vector(popeffectif,0,AGESUP); */
                   8920: /*     free_vector(popcount,0,AGESUP); */
                   8921: /*   } */
                   8922: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8923: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8924: /*   fclose(ficrespop); */
                   8925: /* } /\* End of popforecast *\/ */
1.218     brouard  8926:  
1.126     brouard  8927: int fileappend(FILE *fichier, char *optionfich)
                   8928: {
                   8929:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8930:     printf("Problem with file: %s\n", optionfich);
                   8931:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8932:     return (0);
                   8933:   }
                   8934:   fflush(fichier);
                   8935:   return (1);
                   8936: }
                   8937: 
                   8938: 
                   8939: /**************** function prwizard **********************/
                   8940: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8941: {
                   8942: 
                   8943:   /* Wizard to print covariance matrix template */
                   8944: 
1.164     brouard  8945:   char ca[32], cb[32];
                   8946:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8947:   int numlinepar;
                   8948: 
                   8949:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8950:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8951:   for(i=1; i <=nlstate; i++){
                   8952:     jj=0;
                   8953:     for(j=1; j <=nlstate+ndeath; j++){
                   8954:       if(j==i) continue;
                   8955:       jj++;
                   8956:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8957:       printf("%1d%1d",i,j);
                   8958:       fprintf(ficparo,"%1d%1d",i,j);
                   8959:       for(k=1; k<=ncovmodel;k++){
                   8960:        /*        printf(" %lf",param[i][j][k]); */
                   8961:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8962:        printf(" 0.");
                   8963:        fprintf(ficparo," 0.");
                   8964:       }
                   8965:       printf("\n");
                   8966:       fprintf(ficparo,"\n");
                   8967:     }
                   8968:   }
                   8969:   printf("# Scales (for hessian or gradient estimation)\n");
                   8970:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8971:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8972:   for(i=1; i <=nlstate; i++){
                   8973:     jj=0;
                   8974:     for(j=1; j <=nlstate+ndeath; j++){
                   8975:       if(j==i) continue;
                   8976:       jj++;
                   8977:       fprintf(ficparo,"%1d%1d",i,j);
                   8978:       printf("%1d%1d",i,j);
                   8979:       fflush(stdout);
                   8980:       for(k=1; k<=ncovmodel;k++){
                   8981:        /*      printf(" %le",delti3[i][j][k]); */
                   8982:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8983:        printf(" 0.");
                   8984:        fprintf(ficparo," 0.");
                   8985:       }
                   8986:       numlinepar++;
                   8987:       printf("\n");
                   8988:       fprintf(ficparo,"\n");
                   8989:     }
                   8990:   }
                   8991:   printf("# Covariance matrix\n");
                   8992: /* # 121 Var(a12)\n\ */
                   8993: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8994: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8995: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8996: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8997: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8998: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8999: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9000:   fflush(stdout);
                   9001:   fprintf(ficparo,"# Covariance matrix\n");
                   9002:   /* # 121 Var(a12)\n\ */
                   9003:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9004:   /* #   ...\n\ */
                   9005:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9006:   
                   9007:   for(itimes=1;itimes<=2;itimes++){
                   9008:     jj=0;
                   9009:     for(i=1; i <=nlstate; i++){
                   9010:       for(j=1; j <=nlstate+ndeath; j++){
                   9011:        if(j==i) continue;
                   9012:        for(k=1; k<=ncovmodel;k++){
                   9013:          jj++;
                   9014:          ca[0]= k+'a'-1;ca[1]='\0';
                   9015:          if(itimes==1){
                   9016:            printf("#%1d%1d%d",i,j,k);
                   9017:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9018:          }else{
                   9019:            printf("%1d%1d%d",i,j,k);
                   9020:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9021:            /*  printf(" %.5le",matcov[i][j]); */
                   9022:          }
                   9023:          ll=0;
                   9024:          for(li=1;li <=nlstate; li++){
                   9025:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9026:              if(lj==li) continue;
                   9027:              for(lk=1;lk<=ncovmodel;lk++){
                   9028:                ll++;
                   9029:                if(ll<=jj){
                   9030:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9031:                  if(ll<jj){
                   9032:                    if(itimes==1){
                   9033:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9034:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9035:                    }else{
                   9036:                      printf(" 0.");
                   9037:                      fprintf(ficparo," 0.");
                   9038:                    }
                   9039:                  }else{
                   9040:                    if(itimes==1){
                   9041:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9042:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9043:                    }else{
                   9044:                      printf(" 0.");
                   9045:                      fprintf(ficparo," 0.");
                   9046:                    }
                   9047:                  }
                   9048:                }
                   9049:              } /* end lk */
                   9050:            } /* end lj */
                   9051:          } /* end li */
                   9052:          printf("\n");
                   9053:          fprintf(ficparo,"\n");
                   9054:          numlinepar++;
                   9055:        } /* end k*/
                   9056:       } /*end j */
                   9057:     } /* end i */
                   9058:   } /* end itimes */
                   9059: 
                   9060: } /* end of prwizard */
                   9061: /******************* Gompertz Likelihood ******************************/
                   9062: double gompertz(double x[])
                   9063: { 
1.302   ! brouard  9064:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9065:   int i,n=0; /* n is the size of the sample */
                   9066: 
1.220     brouard  9067:   for (i=1;i<=imx ; i++) {
1.126     brouard  9068:     sump=sump+weight[i];
                   9069:     /*    sump=sump+1;*/
                   9070:     num=num+1;
                   9071:   }
1.302   ! brouard  9072:   L=0.0;
        !          9073:   /* agegomp=AGEGOMP; */
1.126     brouard  9074:   /* for (i=0; i<=imx; i++) 
                   9075:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9076: 
1.302   ! brouard  9077:   for (i=1;i<=imx ; i++) {
        !          9078:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
        !          9079:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
        !          9080:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
        !          9081:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
        !          9082:      * +
        !          9083:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
        !          9084:      */
        !          9085:      if (wav[i] > 1 || agedc[i] < AGESUP) {
        !          9086:        if (cens[i] == 1){
        !          9087:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
        !          9088:        } else if (cens[i] == 0){
1.126     brouard  9089:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302   ! brouard  9090:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
        !          9091:       } else
        !          9092:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9093:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302   ! brouard  9094:        L=L+A*weight[i];
1.126     brouard  9095:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302   ! brouard  9096:      }
        !          9097:   }
1.126     brouard  9098: 
1.302   ! brouard  9099:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9100:  
                   9101:   return -2*L*num/sump;
                   9102: }
                   9103: 
1.136     brouard  9104: #ifdef GSL
                   9105: /******************* Gompertz_f Likelihood ******************************/
                   9106: double gompertz_f(const gsl_vector *v, void *params)
                   9107: { 
1.302   ! brouard  9108:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9109:   double *x= (double *) v->data;
                   9110:   int i,n=0; /* n is the size of the sample */
                   9111: 
                   9112:   for (i=0;i<=imx-1 ; i++) {
                   9113:     sump=sump+weight[i];
                   9114:     /*    sump=sump+1;*/
                   9115:     num=num+1;
                   9116:   }
                   9117:  
                   9118:  
                   9119:   /* for (i=0; i<=imx; i++) 
                   9120:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9121:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9122:   for (i=1;i<=imx ; i++)
                   9123:     {
                   9124:       if (cens[i] == 1 && wav[i]>1)
                   9125:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9126:       
                   9127:       if (cens[i] == 0 && wav[i]>1)
                   9128:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9129:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9130:       
                   9131:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9132:       if (wav[i] > 1 ) { /* ??? */
                   9133:        LL=LL+A*weight[i];
                   9134:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9135:       }
                   9136:     }
                   9137: 
                   9138:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9139:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9140:  
                   9141:   return -2*LL*num/sump;
                   9142: }
                   9143: #endif
                   9144: 
1.126     brouard  9145: /******************* Printing html file ***********/
1.201     brouard  9146: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9147:                  int lastpass, int stepm, int weightopt, char model[],\
                   9148:                  int imx,  double p[],double **matcov,double agemortsup){
                   9149:   int i,k;
                   9150: 
                   9151:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9152:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9153:   for (i=1;i<=2;i++) 
                   9154:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9155:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9156:   fprintf(fichtm,"</ul>");
                   9157: 
                   9158: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9159: 
                   9160:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9161: 
                   9162:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9163:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9164: 
                   9165:  
                   9166:   fflush(fichtm);
                   9167: }
                   9168: 
                   9169: /******************* Gnuplot file **************/
1.201     brouard  9170: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9171: 
                   9172:   char dirfileres[132],optfileres[132];
1.164     brouard  9173: 
1.126     brouard  9174:   int ng;
                   9175: 
                   9176: 
                   9177:   /*#ifdef windows */
                   9178:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9179:     /*#endif */
                   9180: 
                   9181: 
                   9182:   strcpy(dirfileres,optionfilefiname);
                   9183:   strcpy(optfileres,"vpl");
1.199     brouard  9184:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9185:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9186:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9187:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9188:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9189: 
                   9190: } 
                   9191: 
1.136     brouard  9192: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9193: {
1.126     brouard  9194: 
1.136     brouard  9195:   /*-------- data file ----------*/
                   9196:   FILE *fic;
                   9197:   char dummy[]="                         ";
1.240     brouard  9198:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9199:   int lstra;
1.136     brouard  9200:   int linei, month, year,iout;
1.302   ! brouard  9201:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9202:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9203:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9204:   char *stratrunc;
1.223     brouard  9205: 
1.240     brouard  9206:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9207:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9208: 
1.240     brouard  9209:   for(v=1; v <=ncovcol;v++){
                   9210:     DummyV[v]=0;
                   9211:     FixedV[v]=0;
                   9212:   }
                   9213:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9214:     DummyV[v]=1;
                   9215:     FixedV[v]=0;
                   9216:   }
                   9217:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9218:     DummyV[v]=0;
                   9219:     FixedV[v]=1;
                   9220:   }
                   9221:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9222:     DummyV[v]=1;
                   9223:     FixedV[v]=1;
                   9224:   }
                   9225:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9226:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9227:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9228:   }
1.126     brouard  9229: 
1.136     brouard  9230:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9231:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9232:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9233:   }
1.126     brouard  9234: 
1.302   ! brouard  9235:     /* Is it a BOM UTF-8 Windows file? */
        !          9236:   /* First data line */
        !          9237:   linei=0;
        !          9238:   while(fgets(line, MAXLINE, fic)) {
        !          9239:     noffset=0;
        !          9240:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
        !          9241:     {
        !          9242:       noffset=noffset+3;
        !          9243:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
        !          9244:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
        !          9245:       fflush(ficlog); return 1;
        !          9246:     }
        !          9247:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
        !          9248:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
        !          9249:     {
        !          9250:       noffset=noffset+2;
        !          9251:       printf("# Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
        !          9252:       fprintf(ficlog,"# Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
        !          9253:       fflush(ficlog); return 1;
        !          9254:     }
        !          9255:     else if( line[0] == 0 && line[1] == 0)
        !          9256:     {
        !          9257:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
        !          9258:        noffset=noffset+4;
        !          9259:        printf("# Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
        !          9260:        fprintf(ficlog,"# Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
        !          9261:        fflush(ficlog); return 1;
        !          9262:       }
        !          9263:     } else{
        !          9264:       ;/*printf(" Not a BOM file\n");*/
        !          9265:     }
        !          9266:         /* If line starts with a # it is a comment */
        !          9267:     if (line[noffset] == '#') {
        !          9268:       linei=linei+1;
        !          9269:       break;
        !          9270:     }else{
        !          9271:       break;
        !          9272:     }
        !          9273:   }
        !          9274:   fclose(fic);
        !          9275:   if((fic=fopen(datafile,"r"))==NULL)    {
        !          9276:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
        !          9277:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
        !          9278:   }
        !          9279:   /* Not a Bom file */
        !          9280:   
1.136     brouard  9281:   i=1;
                   9282:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9283:     linei=linei+1;
                   9284:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9285:       if(line[j] == '\t')
                   9286:        line[j] = ' ';
                   9287:     }
                   9288:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9289:       ;
                   9290:     };
                   9291:     line[j+1]=0;  /* Trims blanks at end of line */
                   9292:     if(line[0]=='#'){
                   9293:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9294:       printf("Comment line\n%s\n",line);
                   9295:       continue;
                   9296:     }
                   9297:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9298:     strcpy(line, linetmp);
1.223     brouard  9299:     
                   9300:     /* Loops on waves */
                   9301:     for (j=maxwav;j>=1;j--){
                   9302:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9303:        cutv(stra, strb, line, ' '); 
                   9304:        if(strb[0]=='.') { /* Missing value */
                   9305:          lval=-1;
                   9306:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9307:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9308:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9309:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9310:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9311:            return 1;
                   9312:          }
                   9313:        }else{
                   9314:          errno=0;
                   9315:          /* what_kind_of_number(strb); */
                   9316:          dval=strtod(strb,&endptr); 
                   9317:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9318:          /* if(strb != endptr && *endptr == '\0') */
                   9319:          /*    dval=dlval; */
                   9320:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9321:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9322:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9323:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9324:            return 1;
                   9325:          }
                   9326:          cotqvar[j][iv][i]=dval; 
                   9327:          cotvar[j][ntv+iv][i]=dval; 
                   9328:        }
                   9329:        strcpy(line,stra);
1.223     brouard  9330:       }/* end loop ntqv */
1.225     brouard  9331:       
1.223     brouard  9332:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9333:        cutv(stra, strb, line, ' '); 
                   9334:        if(strb[0]=='.') { /* Missing value */
                   9335:          lval=-1;
                   9336:        }else{
                   9337:          errno=0;
                   9338:          lval=strtol(strb,&endptr,10); 
                   9339:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9340:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9341:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9342:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9343:            return 1;
                   9344:          }
                   9345:        }
                   9346:        if(lval <-1 || lval >1){
                   9347:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9348:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9349:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9350:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9351:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9352:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9353:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9354:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9355:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9356:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9357:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9358:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9359:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9360:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9361:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9362:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9363:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9364:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9365:          return 1;
                   9366:        }
                   9367:        cotvar[j][iv][i]=(double)(lval);
                   9368:        strcpy(line,stra);
1.223     brouard  9369:       }/* end loop ntv */
1.225     brouard  9370:       
1.223     brouard  9371:       /* Statuses  at wave */
1.137     brouard  9372:       cutv(stra, strb, line, ' '); 
1.223     brouard  9373:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9374:        lval=-1;
1.136     brouard  9375:       }else{
1.238     brouard  9376:        errno=0;
                   9377:        lval=strtol(strb,&endptr,10); 
                   9378:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9379:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9380:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9381:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9382:          return 1;
                   9383:        }
1.136     brouard  9384:       }
1.225     brouard  9385:       
1.136     brouard  9386:       s[j][i]=lval;
1.225     brouard  9387:       
1.223     brouard  9388:       /* Date of Interview */
1.136     brouard  9389:       strcpy(line,stra);
                   9390:       cutv(stra, strb,line,' ');
1.169     brouard  9391:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9392:       }
1.169     brouard  9393:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9394:        month=99;
                   9395:        year=9999;
1.136     brouard  9396:       }else{
1.225     brouard  9397:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9398:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9399:        return 1;
1.136     brouard  9400:       }
                   9401:       anint[j][i]= (double) year; 
1.302   ! brouard  9402:       mint[j][i]= (double)month;
        !          9403:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
        !          9404:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
        !          9405:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
        !          9406:       /* } */
1.136     brouard  9407:       strcpy(line,stra);
1.223     brouard  9408:     } /* End loop on waves */
1.225     brouard  9409:     
1.223     brouard  9410:     /* Date of death */
1.136     brouard  9411:     cutv(stra, strb,line,' '); 
1.169     brouard  9412:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9413:     }
1.169     brouard  9414:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9415:       month=99;
                   9416:       year=9999;
                   9417:     }else{
1.141     brouard  9418:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9419:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9420:       return 1;
1.136     brouard  9421:     }
                   9422:     andc[i]=(double) year; 
                   9423:     moisdc[i]=(double) month; 
                   9424:     strcpy(line,stra);
                   9425:     
1.223     brouard  9426:     /* Date of birth */
1.136     brouard  9427:     cutv(stra, strb,line,' '); 
1.169     brouard  9428:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9429:     }
1.169     brouard  9430:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9431:       month=99;
                   9432:       year=9999;
                   9433:     }else{
1.141     brouard  9434:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9435:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9436:       return 1;
1.136     brouard  9437:     }
                   9438:     if (year==9999) {
1.141     brouard  9439:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9440:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9441:       return 1;
                   9442:       
1.136     brouard  9443:     }
                   9444:     annais[i]=(double)(year);
1.302   ! brouard  9445:     moisnais[i]=(double)(month);
        !          9446:     for (j=1;j<=maxwav;j++){
        !          9447:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
        !          9448:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
        !          9449:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
        !          9450:       }
        !          9451:     }
        !          9452: 
1.136     brouard  9453:     strcpy(line,stra);
1.225     brouard  9454:     
1.223     brouard  9455:     /* Sample weight */
1.136     brouard  9456:     cutv(stra, strb,line,' '); 
                   9457:     errno=0;
                   9458:     dval=strtod(strb,&endptr); 
                   9459:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9460:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9461:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9462:       fflush(ficlog);
                   9463:       return 1;
                   9464:     }
                   9465:     weight[i]=dval; 
                   9466:     strcpy(line,stra);
1.225     brouard  9467:     
1.223     brouard  9468:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9469:       cutv(stra, strb, line, ' '); 
                   9470:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9471:        lval=-1;
1.223     brouard  9472:       }else{
1.225     brouard  9473:        errno=0;
                   9474:        /* what_kind_of_number(strb); */
                   9475:        dval=strtod(strb,&endptr);
                   9476:        /* if(strb != endptr && *endptr == '\0') */
                   9477:        /*   dval=dlval; */
                   9478:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9479:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9480:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9481:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9482:          return 1;
                   9483:        }
                   9484:        coqvar[iv][i]=dval; 
1.226     brouard  9485:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9486:       }
                   9487:       strcpy(line,stra);
                   9488:     }/* end loop nqv */
1.136     brouard  9489:     
1.223     brouard  9490:     /* Covariate values */
1.136     brouard  9491:     for (j=ncovcol;j>=1;j--){
                   9492:       cutv(stra, strb,line,' '); 
1.223     brouard  9493:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9494:        lval=-1;
1.136     brouard  9495:       }else{
1.225     brouard  9496:        errno=0;
                   9497:        lval=strtol(strb,&endptr,10); 
                   9498:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9499:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9500:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9501:          return 1;
                   9502:        }
1.136     brouard  9503:       }
                   9504:       if(lval <-1 || lval >1){
1.225     brouard  9505:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9506:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9507:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9508:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9509:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9510:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9511:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9512:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9513:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9514:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9515:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9516:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9517:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9518:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9519:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9520:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9521:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9522:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9523:        return 1;
1.136     brouard  9524:       }
                   9525:       covar[j][i]=(double)(lval);
                   9526:       strcpy(line,stra);
                   9527:     }  
                   9528:     lstra=strlen(stra);
1.225     brouard  9529:     
1.136     brouard  9530:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9531:       stratrunc = &(stra[lstra-9]);
                   9532:       num[i]=atol(stratrunc);
                   9533:     }
                   9534:     else
                   9535:       num[i]=atol(stra);
                   9536:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9537:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9538:     
                   9539:     i=i+1;
                   9540:   } /* End loop reading  data */
1.225     brouard  9541:   
1.136     brouard  9542:   *imax=i-1; /* Number of individuals */
                   9543:   fclose(fic);
1.225     brouard  9544:   
1.136     brouard  9545:   return (0);
1.164     brouard  9546:   /* endread: */
1.225     brouard  9547:   printf("Exiting readdata: ");
                   9548:   fclose(fic);
                   9549:   return (1);
1.223     brouard  9550: }
1.126     brouard  9551: 
1.234     brouard  9552: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9553:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9554:   while (*p2 == ' ')
1.234     brouard  9555:     p2++; 
                   9556:   /* while ((*p1++ = *p2++) !=0) */
                   9557:   /*   ; */
                   9558:   /* do */
                   9559:   /*   while (*p2 == ' ') */
                   9560:   /*     p2++; */
                   9561:   /* while (*p1++ == *p2++); */
                   9562:   *stri=p2; 
1.145     brouard  9563: }
                   9564: 
1.235     brouard  9565: int decoderesult ( char resultline[], int nres)
1.230     brouard  9566: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9567: {
1.235     brouard  9568:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9569:   char resultsav[MAXLINE];
1.234     brouard  9570:   int resultmodel[MAXLINE];
                   9571:   int modelresult[MAXLINE];
1.230     brouard  9572:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9573: 
1.234     brouard  9574:   removefirstspace(&resultline);
1.233     brouard  9575:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9576: 
                   9577:   if (strstr(resultline,"v") !=0){
                   9578:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9579:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9580:     return 1;
                   9581:   }
                   9582:   trimbb(resultsav, resultline);
                   9583:   if (strlen(resultsav) >1){
                   9584:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9585:   }
1.253     brouard  9586:   if(j == 0){ /* Resultline but no = */
                   9587:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9588:     return (0);
                   9589:   }
                   9590:     
1.234     brouard  9591:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9592:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9593:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9594:   }
                   9595:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9596:     if(nbocc(resultsav,'=') >1){
                   9597:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9598:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9599:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9600:     }else
                   9601:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9602:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9603:     
1.230     brouard  9604:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9605:     Tvarsel[k]=atoi(strc);
                   9606:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9607:     /* cptcovsel++;     */
                   9608:     if (nbocc(stra,'=') >0)
                   9609:       strcpy(resultsav,stra); /* and analyzes it */
                   9610:   }
1.235     brouard  9611:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9612:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9613:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9614:       match=0;
1.236     brouard  9615:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9616:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9617:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9618:          match=1;
                   9619:          break;
                   9620:        }
                   9621:       }
                   9622:       if(match == 0){
                   9623:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9624:       }
                   9625:     }
                   9626:   }
1.235     brouard  9627:   /* Checking for missing or useless values in comparison of current model needs */
                   9628:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9629:     match=0;
1.235     brouard  9630:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9631:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9632:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9633:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9634:          ++match;
                   9635:        }
                   9636:       }
                   9637:     }
                   9638:     if(match == 0){
                   9639:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9640:     }else if(match > 1){
                   9641:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9642:     }
                   9643:   }
1.235     brouard  9644:       
1.234     brouard  9645:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9646:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9647:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9648:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9649:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9650:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9651:   /*    1 0 0 0 */
                   9652:   /*    2 1 0 0 */
                   9653:   /*    3 0 1 0 */ 
                   9654:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9655:   /*    5 0 0 1 */
                   9656:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9657:   /*    7 0 1 1 */
                   9658:   /*    8 1 1 1 */
1.237     brouard  9659:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9660:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9661:   /* V5*age V5 known which value for nres?  */
                   9662:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9663:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9664:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9665:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9666:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9667:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9668:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9669:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9670:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9671:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9672:       k4++;;
                   9673:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9674:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9675:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9676:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9677:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9678:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9679:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9680:       k4q++;;
                   9681:     }
                   9682:   }
1.234     brouard  9683:   
1.235     brouard  9684:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9685:   return (0);
                   9686: }
1.235     brouard  9687: 
1.230     brouard  9688: int decodemodel( char model[], int lastobs)
                   9689:  /**< This routine decodes the model and returns:
1.224     brouard  9690:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9691:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9692:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9693:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9694:        * - cptcovage number of covariates with age*products =2
                   9695:        * - cptcovs number of simple covariates
                   9696:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9697:        *     which is a new column after the 9 (ncovcol) variables. 
                   9698:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9699:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9700:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9701:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9702:        */
1.136     brouard  9703: {
1.238     brouard  9704:   int i, j, k, ks, v;
1.227     brouard  9705:   int  j1, k1, k2, k3, k4;
1.136     brouard  9706:   char modelsav[80];
1.145     brouard  9707:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9708:   char *strpt;
1.136     brouard  9709: 
1.145     brouard  9710:   /*removespace(model);*/
1.136     brouard  9711:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9712:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9713:     if (strstr(model,"AGE") !=0){
1.192     brouard  9714:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9715:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9716:       return 1;
                   9717:     }
1.141     brouard  9718:     if (strstr(model,"v") !=0){
                   9719:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9720:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9721:       return 1;
                   9722:     }
1.187     brouard  9723:     strcpy(modelsav,model); 
                   9724:     if ((strpt=strstr(model,"age*age")) !=0){
                   9725:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9726:       if(strpt != model){
1.234     brouard  9727:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9728:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9729:  corresponding column of parameters.\n",model);
1.234     brouard  9730:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9731:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9732:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9733:        return 1;
1.225     brouard  9734:       }
1.187     brouard  9735:       nagesqr=1;
                   9736:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9737:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9738:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9739:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9740:       else 
1.234     brouard  9741:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9742:     }else
                   9743:       nagesqr=0;
                   9744:     if (strlen(modelsav) >1){
                   9745:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9746:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9747:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9748:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9749:                     * cst, age and age*age 
                   9750:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9751:       /* including age products which are counted in cptcovage.
                   9752:        * but the covariates which are products must be treated 
                   9753:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9754:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9755:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9756:       
                   9757:       
1.187     brouard  9758:       /*   Design
                   9759:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9760:        *  <          ncovcol=8                >
                   9761:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9762:        *   k=  1    2      3       4     5       6      7        8
                   9763:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9764:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9765:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9766:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9767:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9768:        *  Tage[++cptcovage]=k
                   9769:        *       if products, new covar are created after ncovcol with k1
                   9770:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9771:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9772:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9773:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9774:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9775:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9776:        *  <          ncovcol=8                >
                   9777:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9778:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9779:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9780:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9781:        * p Tprod[1]@2={                         6, 5}
                   9782:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9783:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9784:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9785:        *How to reorganize?
                   9786:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9787:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9788:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9789:        * Struct []
                   9790:        */
1.225     brouard  9791:       
1.187     brouard  9792:       /* This loop fills the array Tvar from the string 'model'.*/
                   9793:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9794:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9795:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9796:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9797:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9798:       /*       k=1 Tvar[1]=2 (from V2) */
                   9799:       /*       k=5 Tvar[5] */
                   9800:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9801:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9802:       /*       } */
1.198     brouard  9803:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9804:       /*
                   9805:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9806:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9807:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9808:       }
1.187     brouard  9809:       cptcovage=0;
                   9810:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9811:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9812:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9813:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9814:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9815:        /*scanf("%d",i);*/
                   9816:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9817:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9818:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9819:            /* covar is not filled and then is empty */
                   9820:            cptcovprod--;
                   9821:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9822:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9823:            Typevar[k]=1;  /* 1 for age product */
                   9824:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9825:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9826:            /*printf("stre=%s ", stre);*/
                   9827:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9828:            cptcovprod--;
                   9829:            cutl(stre,strb,strc,'V');
                   9830:            Tvar[k]=atoi(stre);
                   9831:            Typevar[k]=1;  /* 1 for age product */
                   9832:            cptcovage++;
                   9833:            Tage[cptcovage]=k;
                   9834:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9835:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9836:            cptcovn++;
                   9837:            cptcovprodnoage++;k1++;
                   9838:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9839:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9840:                                                because this model-covariate is a construction we invent a new column
                   9841:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9842:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9843:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9844:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9845:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9846:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9847:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9848:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9849:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9850:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9851:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9852:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9853:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9854:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9855:            for (i=1; i<=lastobs;i++){
                   9856:              /* Computes the new covariate which is a product of
                   9857:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9858:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9859:            }
                   9860:          } /* End age is not in the model */
                   9861:        } /* End if model includes a product */
                   9862:        else { /* no more sum */
                   9863:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9864:          /*  scanf("%d",i);*/
                   9865:          cutl(strd,strc,strb,'V');
                   9866:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9867:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9868:          Tvar[k]=atoi(strd);
                   9869:          Typevar[k]=0;  /* 0 for simple covariates */
                   9870:        }
                   9871:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9872:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9873:                                  scanf("%d",i);*/
1.187     brouard  9874:       } /* end of loop + on total covariates */
                   9875:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9876:   } /* end if strlen(model == 0) */
1.136     brouard  9877:   
                   9878:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9879:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9880:   
1.136     brouard  9881:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9882:      printf("cptcovprod=%d ", cptcovprod);
                   9883:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9884:      scanf("%d ",i);*/
                   9885: 
                   9886: 
1.230     brouard  9887: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9888:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9889: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9890:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9891:    k =           1    2   3     4       5       6      7      8        9
                   9892:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9893:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9894:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9895:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9896:          Tmodelind[combination of covar]=k;
1.225     brouard  9897: */  
                   9898: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9899:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9900:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9901:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9902:   printf("Model=%s\n\
                   9903: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9904: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9905: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9906:   fprintf(ficlog,"Model=%s\n\
                   9907: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9908: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9909: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9910:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9911:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9912:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9913:       Fixed[k]= 0;
                   9914:       Dummy[k]= 0;
1.225     brouard  9915:       ncoveff++;
1.232     brouard  9916:       ncovf++;
1.234     brouard  9917:       nsd++;
                   9918:       modell[k].maintype= FTYPE;
                   9919:       TvarsD[nsd]=Tvar[k];
                   9920:       TvarsDind[nsd]=k;
                   9921:       TvarF[ncovf]=Tvar[k];
                   9922:       TvarFind[ncovf]=k;
                   9923:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9924:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9925:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9926:       Fixed[k]= 0;
                   9927:       Dummy[k]= 0;
                   9928:       ncoveff++;
                   9929:       ncovf++;
                   9930:       modell[k].maintype= FTYPE;
                   9931:       TvarF[ncovf]=Tvar[k];
                   9932:       TvarFind[ncovf]=k;
1.230     brouard  9933:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9934:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9935:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9936:       Fixed[k]= 0;
                   9937:       Dummy[k]= 1;
1.230     brouard  9938:       nqfveff++;
1.234     brouard  9939:       modell[k].maintype= FTYPE;
                   9940:       modell[k].subtype= FQ;
                   9941:       nsq++;
                   9942:       TvarsQ[nsq]=Tvar[k];
                   9943:       TvarsQind[nsq]=k;
1.232     brouard  9944:       ncovf++;
1.234     brouard  9945:       TvarF[ncovf]=Tvar[k];
                   9946:       TvarFind[ncovf]=k;
1.231     brouard  9947:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9948:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9949:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9950:       Fixed[k]= 1;
                   9951:       Dummy[k]= 0;
1.225     brouard  9952:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9953:       modell[k].maintype= VTYPE;
                   9954:       modell[k].subtype= VD;
                   9955:       nsd++;
                   9956:       TvarsD[nsd]=Tvar[k];
                   9957:       TvarsDind[nsd]=k;
                   9958:       ncovv++; /* Only simple time varying variables */
                   9959:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9960:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9961:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9962:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9963:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9964:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9965:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9966:       Fixed[k]= 1;
                   9967:       Dummy[k]= 1;
                   9968:       nqtveff++;
                   9969:       modell[k].maintype= VTYPE;
                   9970:       modell[k].subtype= VQ;
                   9971:       ncovv++; /* Only simple time varying variables */
                   9972:       nsq++;
                   9973:       TvarsQ[nsq]=Tvar[k];
                   9974:       TvarsQind[nsq]=k;
                   9975:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9976:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9977:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9978:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9979:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9980:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9981:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9982:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9983:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9984:       ncova++;
                   9985:       TvarA[ncova]=Tvar[k];
                   9986:       TvarAind[ncova]=k;
1.231     brouard  9987:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9988:        Fixed[k]= 2;
                   9989:        Dummy[k]= 2;
                   9990:        modell[k].maintype= ATYPE;
                   9991:        modell[k].subtype= APFD;
                   9992:        /* ncoveff++; */
1.227     brouard  9993:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9994:        Fixed[k]= 2;
                   9995:        Dummy[k]= 3;
                   9996:        modell[k].maintype= ATYPE;
                   9997:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9998:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9999:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10000:        Fixed[k]= 3;
                   10001:        Dummy[k]= 2;
                   10002:        modell[k].maintype= ATYPE;
                   10003:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10004:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10005:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10006:        Fixed[k]= 3;
                   10007:        Dummy[k]= 3;
                   10008:        modell[k].maintype= ATYPE;
                   10009:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10010:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10011:       }
                   10012:     }else if (Typevar[k] == 2) {  /* product without age */
                   10013:       k1=Tposprod[k];
                   10014:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10015:        if(Tvard[k1][2] <=ncovcol){
                   10016:          Fixed[k]= 1;
                   10017:          Dummy[k]= 0;
                   10018:          modell[k].maintype= FTYPE;
                   10019:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10020:          ncovf++; /* Fixed variables without age */
                   10021:          TvarF[ncovf]=Tvar[k];
                   10022:          TvarFind[ncovf]=k;
                   10023:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10024:          Fixed[k]= 0;  /* or 2 ?*/
                   10025:          Dummy[k]= 1;
                   10026:          modell[k].maintype= FTYPE;
                   10027:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10028:          ncovf++; /* Varying variables without age */
                   10029:          TvarF[ncovf]=Tvar[k];
                   10030:          TvarFind[ncovf]=k;
                   10031:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10032:          Fixed[k]= 1;
                   10033:          Dummy[k]= 0;
                   10034:          modell[k].maintype= VTYPE;
                   10035:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10036:          ncovv++; /* Varying variables without age */
                   10037:          TvarV[ncovv]=Tvar[k];
                   10038:          TvarVind[ncovv]=k;
                   10039:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10040:          Fixed[k]= 1;
                   10041:          Dummy[k]= 1;
                   10042:          modell[k].maintype= VTYPE;
                   10043:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10044:          ncovv++; /* Varying variables without age */
                   10045:          TvarV[ncovv]=Tvar[k];
                   10046:          TvarVind[ncovv]=k;
                   10047:        }
1.227     brouard  10048:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10049:        if(Tvard[k1][2] <=ncovcol){
                   10050:          Fixed[k]= 0;  /* or 2 ?*/
                   10051:          Dummy[k]= 1;
                   10052:          modell[k].maintype= FTYPE;
                   10053:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10054:          ncovf++; /* Fixed variables without age */
                   10055:          TvarF[ncovf]=Tvar[k];
                   10056:          TvarFind[ncovf]=k;
                   10057:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10058:          Fixed[k]= 1;
                   10059:          Dummy[k]= 1;
                   10060:          modell[k].maintype= VTYPE;
                   10061:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10062:          ncovv++; /* Varying variables without age */
                   10063:          TvarV[ncovv]=Tvar[k];
                   10064:          TvarVind[ncovv]=k;
                   10065:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10066:          Fixed[k]= 1;
                   10067:          Dummy[k]= 1;
                   10068:          modell[k].maintype= VTYPE;
                   10069:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10070:          ncovv++; /* Varying variables without age */
                   10071:          TvarV[ncovv]=Tvar[k];
                   10072:          TvarVind[ncovv]=k;
                   10073:          ncovv++; /* Varying variables without age */
                   10074:          TvarV[ncovv]=Tvar[k];
                   10075:          TvarVind[ncovv]=k;
                   10076:        }
1.227     brouard  10077:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10078:        if(Tvard[k1][2] <=ncovcol){
                   10079:          Fixed[k]= 1;
                   10080:          Dummy[k]= 1;
                   10081:          modell[k].maintype= VTYPE;
                   10082:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10083:          ncovv++; /* Varying variables without age */
                   10084:          TvarV[ncovv]=Tvar[k];
                   10085:          TvarVind[ncovv]=k;
                   10086:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10087:          Fixed[k]= 1;
                   10088:          Dummy[k]= 1;
                   10089:          modell[k].maintype= VTYPE;
                   10090:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10091:          ncovv++; /* Varying variables without age */
                   10092:          TvarV[ncovv]=Tvar[k];
                   10093:          TvarVind[ncovv]=k;
                   10094:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10095:          Fixed[k]= 1;
                   10096:          Dummy[k]= 0;
                   10097:          modell[k].maintype= VTYPE;
                   10098:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10099:          ncovv++; /* Varying variables without age */
                   10100:          TvarV[ncovv]=Tvar[k];
                   10101:          TvarVind[ncovv]=k;
                   10102:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10103:          Fixed[k]= 1;
                   10104:          Dummy[k]= 1;
                   10105:          modell[k].maintype= VTYPE;
                   10106:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10107:          ncovv++; /* Varying variables without age */
                   10108:          TvarV[ncovv]=Tvar[k];
                   10109:          TvarVind[ncovv]=k;
                   10110:        }
1.227     brouard  10111:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10112:        if(Tvard[k1][2] <=ncovcol){
                   10113:          Fixed[k]= 1;
                   10114:          Dummy[k]= 1;
                   10115:          modell[k].maintype= VTYPE;
                   10116:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10117:          ncovv++; /* Varying variables without age */
                   10118:          TvarV[ncovv]=Tvar[k];
                   10119:          TvarVind[ncovv]=k;
                   10120:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10121:          Fixed[k]= 1;
                   10122:          Dummy[k]= 1;
                   10123:          modell[k].maintype= VTYPE;
                   10124:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10125:          ncovv++; /* Varying variables without age */
                   10126:          TvarV[ncovv]=Tvar[k];
                   10127:          TvarVind[ncovv]=k;
                   10128:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10129:          Fixed[k]= 1;
                   10130:          Dummy[k]= 1;
                   10131:          modell[k].maintype= VTYPE;
                   10132:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10133:          ncovv++; /* Varying variables without age */
                   10134:          TvarV[ncovv]=Tvar[k];
                   10135:          TvarVind[ncovv]=k;
                   10136:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10137:          Fixed[k]= 1;
                   10138:          Dummy[k]= 1;
                   10139:          modell[k].maintype= VTYPE;
                   10140:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10141:          ncovv++; /* Varying variables without age */
                   10142:          TvarV[ncovv]=Tvar[k];
                   10143:          TvarVind[ncovv]=k;
                   10144:        }
1.227     brouard  10145:       }else{
1.240     brouard  10146:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10147:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10148:       } /*end k1*/
1.225     brouard  10149:     }else{
1.226     brouard  10150:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10151:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10152:     }
1.227     brouard  10153:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10154:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10155:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10156:   }
                   10157:   /* Searching for doublons in the model */
                   10158:   for(k1=1; k1<= cptcovt;k1++){
                   10159:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10160:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10161:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10162:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10163:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10164:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10165:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10166:            return(1);
                   10167:          }
                   10168:        }else if (Typevar[k1] ==2){
                   10169:          k3=Tposprod[k1];
                   10170:          k4=Tposprod[k2];
                   10171:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10172:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10173:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10174:            return(1);
                   10175:          }
                   10176:        }
1.227     brouard  10177:       }
                   10178:     }
1.225     brouard  10179:   }
                   10180:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10181:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10182:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10183:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10184:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10185:   /*endread:*/
1.225     brouard  10186:   printf("Exiting decodemodel: ");
                   10187:   return (1);
1.136     brouard  10188: }
                   10189: 
1.169     brouard  10190: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10191: {/* Check ages at death */
1.136     brouard  10192:   int i, m;
1.218     brouard  10193:   int firstone=0;
                   10194:   
1.136     brouard  10195:   for (i=1; i<=imx; i++) {
                   10196:     for(m=2; (m<= maxwav); m++) {
                   10197:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10198:        anint[m][i]=9999;
1.216     brouard  10199:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10200:          s[m][i]=-1;
1.136     brouard  10201:       }
                   10202:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10203:        *nberr = *nberr + 1;
1.218     brouard  10204:        if(firstone == 0){
                   10205:          firstone=1;
1.260     brouard  10206:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10207:        }
1.262     brouard  10208:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10209:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10210:       }
                   10211:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10212:        (*nberr)++;
1.259     brouard  10213:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10214:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10215:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10216:       }
                   10217:     }
                   10218:   }
                   10219: 
                   10220:   for (i=1; i<=imx; i++)  {
                   10221:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10222:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10223:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10224:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10225:          if(agedc[i]>0){
                   10226:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10227:              agev[m][i]=agedc[i];
1.214     brouard  10228:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10229:            }else {
1.136     brouard  10230:              if ((int)andc[i]!=9999){
                   10231:                nbwarn++;
                   10232:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10233:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10234:                agev[m][i]=-1;
                   10235:              }
                   10236:            }
1.169     brouard  10237:          } /* agedc > 0 */
1.214     brouard  10238:        } /* end if */
1.136     brouard  10239:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10240:                                 years but with the precision of a month */
                   10241:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10242:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10243:            agev[m][i]=1;
                   10244:          else if(agev[m][i] < *agemin){ 
                   10245:            *agemin=agev[m][i];
                   10246:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10247:          }
                   10248:          else if(agev[m][i] >*agemax){
                   10249:            *agemax=agev[m][i];
1.156     brouard  10250:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10251:          }
                   10252:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10253:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10254:        } /* en if 9*/
1.136     brouard  10255:        else { /* =9 */
1.214     brouard  10256:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10257:          agev[m][i]=1;
                   10258:          s[m][i]=-1;
                   10259:        }
                   10260:       }
1.214     brouard  10261:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10262:        agev[m][i]=1;
1.214     brouard  10263:       else{
                   10264:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10265:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10266:        agev[m][i]=0;
                   10267:       }
                   10268:     } /* End for lastpass */
                   10269:   }
1.136     brouard  10270:     
                   10271:   for (i=1; i<=imx; i++)  {
                   10272:     for(m=firstpass; (m<=lastpass); m++){
                   10273:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10274:        (*nberr)++;
1.136     brouard  10275:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10276:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10277:        return 1;
                   10278:       }
                   10279:     }
                   10280:   }
                   10281: 
                   10282:   /*for (i=1; i<=imx; i++){
                   10283:   for (m=firstpass; (m<lastpass); m++){
                   10284:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10285: }
                   10286: 
                   10287: }*/
                   10288: 
                   10289: 
1.139     brouard  10290:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10291:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10292: 
                   10293:   return (0);
1.164     brouard  10294:  /* endread:*/
1.136     brouard  10295:     printf("Exiting calandcheckages: ");
                   10296:     return (1);
                   10297: }
                   10298: 
1.172     brouard  10299: #if defined(_MSC_VER)
                   10300: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10301: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10302: //#include "stdafx.h"
                   10303: //#include <stdio.h>
                   10304: //#include <tchar.h>
                   10305: //#include <windows.h>
                   10306: //#include <iostream>
                   10307: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10308: 
                   10309: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10310: 
                   10311: BOOL IsWow64()
                   10312: {
                   10313:        BOOL bIsWow64 = FALSE;
                   10314: 
                   10315:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10316:        //  (HANDLE, PBOOL);
                   10317: 
                   10318:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10319: 
                   10320:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10321:        const char funcName[] = "IsWow64Process";
                   10322:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10323:                GetProcAddress(module, funcName);
                   10324: 
                   10325:        if (NULL != fnIsWow64Process)
                   10326:        {
                   10327:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10328:                        &bIsWow64))
                   10329:                        //throw std::exception("Unknown error");
                   10330:                        printf("Unknown error\n");
                   10331:        }
                   10332:        return bIsWow64 != FALSE;
                   10333: }
                   10334: #endif
1.177     brouard  10335: 
1.191     brouard  10336: void syscompilerinfo(int logged)
1.292     brouard  10337: {
                   10338: #include <stdint.h>
                   10339: 
                   10340:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10341:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10342:    /* /GS /W3 /Gy
                   10343:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10344:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10345:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10346:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10347:    */ 
                   10348:    /* 64 bits */
1.185     brouard  10349:    /*
                   10350:      /GS /W3 /Gy
                   10351:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10352:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10353:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10354:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10355:    /* Optimization are useless and O3 is slower than O2 */
                   10356:    /*
                   10357:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10358:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10359:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10360:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10361:    */
1.186     brouard  10362:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10363:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10364:       /PDB:"visual studio
                   10365:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10366:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10367:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10368:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10369:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10370:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10371:       uiAccess='false'"
                   10372:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10373:       /NOLOGO /TLBID:1
                   10374:    */
1.292     brouard  10375: 
                   10376: 
1.177     brouard  10377: #if defined __INTEL_COMPILER
1.178     brouard  10378: #if defined(__GNUC__)
                   10379:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10380: #endif
1.177     brouard  10381: #elif defined(__GNUC__) 
1.179     brouard  10382: #ifndef  __APPLE__
1.174     brouard  10383: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10384: #endif
1.177     brouard  10385:    struct utsname sysInfo;
1.178     brouard  10386:    int cross = CROSS;
                   10387:    if (cross){
                   10388:           printf("Cross-");
1.191     brouard  10389:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10390:    }
1.174     brouard  10391: #endif
                   10392: 
1.191     brouard  10393:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10394: #if defined(__clang__)
1.191     brouard  10395:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10396: #endif
                   10397: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10398:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10399: #endif
                   10400: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10401:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10402: #endif
                   10403: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10404:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10405: #endif
                   10406: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10407:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10408: #endif
                   10409: #if defined(_MSC_VER)
1.191     brouard  10410:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10411: #endif
                   10412: #if defined(__PGI)
1.191     brouard  10413:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10414: #endif
                   10415: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10416:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10417: #endif
1.191     brouard  10418:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10419:    
1.167     brouard  10420: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10421: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10422:     // Windows (x64 and x86)
1.191     brouard  10423:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10424: #elif __unix__ // all unices, not all compilers
                   10425:     // Unix
1.191     brouard  10426:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10427: #elif __linux__
                   10428:     // linux
1.191     brouard  10429:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10430: #elif __APPLE__
1.174     brouard  10431:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10432:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10433: #endif
                   10434: 
                   10435: /*  __MINGW32__          */
                   10436: /*  __CYGWIN__  */
                   10437: /* __MINGW64__  */
                   10438: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10439: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10440: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10441: /* _WIN64  // Defined for applications for Win64. */
                   10442: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10443: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10444: 
1.167     brouard  10445: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10446:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10447: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10448:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10449: #else
1.191     brouard  10450:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10451: #endif
                   10452: 
1.169     brouard  10453: #if defined(__GNUC__)
                   10454: # if defined(__GNUC_PATCHLEVEL__)
                   10455: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10456:                             + __GNUC_MINOR__ * 100 \
                   10457:                             + __GNUC_PATCHLEVEL__)
                   10458: # else
                   10459: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10460:                             + __GNUC_MINOR__ * 100)
                   10461: # endif
1.174     brouard  10462:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10463:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10464: 
                   10465:    if (uname(&sysInfo) != -1) {
                   10466:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10467:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10468:    }
                   10469:    else
                   10470:       perror("uname() error");
1.179     brouard  10471:    //#ifndef __INTEL_COMPILER 
                   10472: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10473:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10474:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10475: #endif
1.169     brouard  10476: #endif
1.172     brouard  10477: 
1.286     brouard  10478:    //   void main ()
1.172     brouard  10479:    //   {
1.169     brouard  10480: #if defined(_MSC_VER)
1.174     brouard  10481:    if (IsWow64()){
1.191     brouard  10482:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10483:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10484:    }
                   10485:    else{
1.191     brouard  10486:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10487:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10488:    }
1.172     brouard  10489:    //     printf("\nPress Enter to continue...");
                   10490:    //     getchar();
                   10491:    //   }
                   10492: 
1.169     brouard  10493: #endif
                   10494:    
1.167     brouard  10495: 
1.219     brouard  10496: }
1.136     brouard  10497: 
1.219     brouard  10498: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10499:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10500:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10501:   /* double ftolpl = 1.e-10; */
1.180     brouard  10502:   double age, agebase, agelim;
1.203     brouard  10503:   double tot;
1.180     brouard  10504: 
1.202     brouard  10505:   strcpy(filerespl,"PL_");
                   10506:   strcat(filerespl,fileresu);
                   10507:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10508:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10509:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10510:   }
1.288     brouard  10511:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10512:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10513:   pstamp(ficrespl);
1.288     brouard  10514:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10515:   fprintf(ficrespl,"#Age ");
                   10516:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10517:   fprintf(ficrespl,"\n");
1.180     brouard  10518:   
1.219     brouard  10519:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10520: 
1.219     brouard  10521:   agebase=ageminpar;
                   10522:   agelim=agemaxpar;
1.180     brouard  10523: 
1.227     brouard  10524:   /* i1=pow(2,ncoveff); */
1.234     brouard  10525:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10526:   if (cptcovn < 1){i1=1;}
1.180     brouard  10527: 
1.238     brouard  10528:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10529:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10530:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10531:        continue;
1.235     brouard  10532: 
1.238     brouard  10533:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10534:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10535:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10536:       /* k=k+1; */
                   10537:       /* to clean */
                   10538:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10539:       fprintf(ficrespl,"#******");
                   10540:       printf("#******");
                   10541:       fprintf(ficlog,"#******");
                   10542:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10543:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10544:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10545:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10546:       }
                   10547:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10548:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10549:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10550:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10551:       }
                   10552:       fprintf(ficrespl,"******\n");
                   10553:       printf("******\n");
                   10554:       fprintf(ficlog,"******\n");
                   10555:       if(invalidvarcomb[k]){
                   10556:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10557:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10558:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10559:        continue;
                   10560:       }
1.219     brouard  10561: 
1.238     brouard  10562:       fprintf(ficrespl,"#Age ");
                   10563:       for(j=1;j<=cptcoveff;j++) {
                   10564:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10565:       }
                   10566:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10567:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10568:     
1.238     brouard  10569:       for (age=agebase; age<=agelim; age++){
                   10570:        /* for (age=agebase; age<=agebase; age++){ */
                   10571:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10572:        fprintf(ficrespl,"%.0f ",age );
                   10573:        for(j=1;j<=cptcoveff;j++)
                   10574:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10575:        tot=0.;
                   10576:        for(i=1; i<=nlstate;i++){
                   10577:          tot +=  prlim[i][i];
                   10578:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10579:        }
                   10580:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10581:       } /* Age */
                   10582:       /* was end of cptcod */
                   10583:     } /* cptcov */
                   10584:   } /* nres */
1.219     brouard  10585:   return 0;
1.180     brouard  10586: }
                   10587: 
1.218     brouard  10588: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10589:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10590:        
                   10591:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10592:    * at any age between ageminpar and agemaxpar
                   10593:         */
1.235     brouard  10594:   int i, j, k, i1, nres=0 ;
1.217     brouard  10595:   /* double ftolpl = 1.e-10; */
                   10596:   double age, agebase, agelim;
                   10597:   double tot;
1.218     brouard  10598:   /* double ***mobaverage; */
                   10599:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10600: 
                   10601:   strcpy(fileresplb,"PLB_");
                   10602:   strcat(fileresplb,fileresu);
                   10603:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10604:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10605:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10606:   }
1.288     brouard  10607:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10608:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10609:   pstamp(ficresplb);
1.288     brouard  10610:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10611:   fprintf(ficresplb,"#Age ");
                   10612:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10613:   fprintf(ficresplb,"\n");
                   10614:   
1.218     brouard  10615:   
                   10616:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10617:   
                   10618:   agebase=ageminpar;
                   10619:   agelim=agemaxpar;
                   10620:   
                   10621:   
1.227     brouard  10622:   i1=pow(2,cptcoveff);
1.218     brouard  10623:   if (cptcovn < 1){i1=1;}
1.227     brouard  10624:   
1.238     brouard  10625:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10626:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10627:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10628:        continue;
                   10629:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10630:       fprintf(ficresplb,"#******");
                   10631:       printf("#******");
                   10632:       fprintf(ficlog,"#******");
                   10633:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10634:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10635:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10636:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10637:       }
                   10638:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10639:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10640:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10641:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10642:       }
                   10643:       fprintf(ficresplb,"******\n");
                   10644:       printf("******\n");
                   10645:       fprintf(ficlog,"******\n");
                   10646:       if(invalidvarcomb[k]){
                   10647:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10648:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10649:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10650:        continue;
                   10651:       }
1.218     brouard  10652:     
1.238     brouard  10653:       fprintf(ficresplb,"#Age ");
                   10654:       for(j=1;j<=cptcoveff;j++) {
                   10655:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10656:       }
                   10657:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10658:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10659:     
                   10660:     
1.238     brouard  10661:       for (age=agebase; age<=agelim; age++){
                   10662:        /* for (age=agebase; age<=agebase; age++){ */
                   10663:        if(mobilavproj > 0){
                   10664:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10665:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10666:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10667:        }else if (mobilavproj == 0){
                   10668:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10669:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10670:          exit(1);
                   10671:        }else{
                   10672:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10673:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10674:          /* printf("TOTOT\n"); */
                   10675:           /* exit(1); */
1.238     brouard  10676:        }
                   10677:        fprintf(ficresplb,"%.0f ",age );
                   10678:        for(j=1;j<=cptcoveff;j++)
                   10679:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10680:        tot=0.;
                   10681:        for(i=1; i<=nlstate;i++){
                   10682:          tot +=  bprlim[i][i];
                   10683:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10684:        }
                   10685:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10686:       } /* Age */
                   10687:       /* was end of cptcod */
1.255     brouard  10688:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10689:     } /* end of any combination */
                   10690:   } /* end of nres */  
1.218     brouard  10691:   /* hBijx(p, bage, fage); */
                   10692:   /* fclose(ficrespijb); */
                   10693:   
                   10694:   return 0;
1.217     brouard  10695: }
1.218     brouard  10696:  
1.180     brouard  10697: int hPijx(double *p, int bage, int fage){
                   10698:     /*------------- h Pij x at various ages ------------*/
                   10699: 
                   10700:   int stepsize;
                   10701:   int agelim;
                   10702:   int hstepm;
                   10703:   int nhstepm;
1.235     brouard  10704:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10705: 
                   10706:   double agedeb;
                   10707:   double ***p3mat;
                   10708: 
1.201     brouard  10709:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10710:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10711:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10712:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10713:     }
                   10714:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10715:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10716:   
                   10717:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10718:     /*if (stepm<=24) stepsize=2;*/
                   10719: 
                   10720:     agelim=AGESUP;
                   10721:     hstepm=stepsize*YEARM; /* Every year of age */
                   10722:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10723:                
1.180     brouard  10724:     /* hstepm=1;   aff par mois*/
                   10725:     pstamp(ficrespij);
                   10726:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10727:     i1= pow(2,cptcoveff);
1.218     brouard  10728:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10729:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10730:                /*      k=k+1;  */
1.235     brouard  10731:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10732:     for(k=1; k<=i1;k++){
1.253     brouard  10733:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10734:        continue;
1.183     brouard  10735:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10736:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10737:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10738:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10739:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10740:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10741:       }
1.183     brouard  10742:       fprintf(ficrespij,"******\n");
                   10743:       
                   10744:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10745:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10746:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10747:        
                   10748:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10749:        
1.183     brouard  10750:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10751:        oldm=oldms;savm=savms;
1.235     brouard  10752:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10753:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10754:        for(i=1; i<=nlstate;i++)
                   10755:          for(j=1; j<=nlstate+ndeath;j++)
                   10756:            fprintf(ficrespij," %1d-%1d",i,j);
                   10757:        fprintf(ficrespij,"\n");
                   10758:        for (h=0; h<=nhstepm; h++){
                   10759:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10760:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10761:          for(i=1; i<=nlstate;i++)
                   10762:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10763:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10764:          fprintf(ficrespij,"\n");
                   10765:        }
1.183     brouard  10766:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10767:        fprintf(ficrespij,"\n");
                   10768:       }
1.180     brouard  10769:       /*}*/
                   10770:     }
1.218     brouard  10771:     return 0;
1.180     brouard  10772: }
1.218     brouard  10773:  
                   10774:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10775:     /*------------- h Bij x at various ages ------------*/
                   10776: 
                   10777:   int stepsize;
1.218     brouard  10778:   /* int agelim; */
                   10779:        int ageminl;
1.217     brouard  10780:   int hstepm;
                   10781:   int nhstepm;
1.238     brouard  10782:   int h, i, i1, j, k, nres;
1.218     brouard  10783:        
1.217     brouard  10784:   double agedeb;
                   10785:   double ***p3mat;
1.218     brouard  10786:        
                   10787:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10788:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10789:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10790:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10791:   }
                   10792:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10793:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10794:   
                   10795:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10796:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10797:   
1.218     brouard  10798:   /* agelim=AGESUP; */
1.289     brouard  10799:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10800:   hstepm=stepsize*YEARM; /* Every year of age */
                   10801:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10802:   
                   10803:   /* hstepm=1;   aff par mois*/
                   10804:   pstamp(ficrespijb);
1.255     brouard  10805:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10806:   i1= pow(2,cptcoveff);
1.218     brouard  10807:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10808:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10809:   /*   k=k+1;  */
1.238     brouard  10810:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10811:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10812:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10813:        continue;
                   10814:       fprintf(ficrespijb,"\n#****** ");
                   10815:       for(j=1;j<=cptcoveff;j++)
                   10816:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10817:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10818:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10819:       }
                   10820:       fprintf(ficrespijb,"******\n");
1.264     brouard  10821:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10822:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10823:        continue;
                   10824:       }
                   10825:       
                   10826:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10827:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10828:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  10829:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   10830:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  10831:        
                   10832:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10833:        
1.266     brouard  10834:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10835:        /* and memory limitations if stepm is small */
                   10836: 
1.238     brouard  10837:        /* oldm=oldms;savm=savms; */
                   10838:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10839:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10840:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10841:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10842:        for(i=1; i<=nlstate;i++)
                   10843:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10844:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10845:        fprintf(ficrespijb,"\n");
1.238     brouard  10846:        for (h=0; h<=nhstepm; h++){
                   10847:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10848:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10849:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10850:          for(i=1; i<=nlstate;i++)
                   10851:            for(j=1; j<=nlstate+ndeath;j++)
                   10852:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10853:          fprintf(ficrespijb,"\n");
                   10854:        }
                   10855:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10856:        fprintf(ficrespijb,"\n");
                   10857:       } /* end age deb */
                   10858:     } /* end combination */
                   10859:   } /* end nres */
1.218     brouard  10860:   return 0;
                   10861:  } /*  hBijx */
1.217     brouard  10862: 
1.180     brouard  10863: 
1.136     brouard  10864: /***********************************************/
                   10865: /**************** Main Program *****************/
                   10866: /***********************************************/
                   10867: 
                   10868: int main(int argc, char *argv[])
                   10869: {
                   10870: #ifdef GSL
                   10871:   const gsl_multimin_fminimizer_type *T;
                   10872:   size_t iteri = 0, it;
                   10873:   int rval = GSL_CONTINUE;
                   10874:   int status = GSL_SUCCESS;
                   10875:   double ssval;
                   10876: #endif
                   10877:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10878:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10879:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10880:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10881:   int jj, ll, li, lj, lk;
1.136     brouard  10882:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10883:   int num_filled;
1.136     brouard  10884:   int itimes;
                   10885:   int NDIM=2;
                   10886:   int vpopbased=0;
1.235     brouard  10887:   int nres=0;
1.258     brouard  10888:   int endishere=0;
1.277     brouard  10889:   int noffset=0;
1.274     brouard  10890:   int ncurrv=0; /* Temporary variable */
                   10891:   
1.164     brouard  10892:   char ca[32], cb[32];
1.136     brouard  10893:   /*  FILE *fichtm; *//* Html File */
                   10894:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10895:   struct stat info;
1.191     brouard  10896:   double agedeb=0.;
1.194     brouard  10897: 
                   10898:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10899:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10900: 
1.165     brouard  10901:   double fret;
1.191     brouard  10902:   double dum=0.; /* Dummy variable */
1.136     brouard  10903:   double ***p3mat;
1.218     brouard  10904:   /* double ***mobaverage; */
1.164     brouard  10905: 
                   10906:   char line[MAXLINE];
1.197     brouard  10907:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10908: 
1.234     brouard  10909:   char  modeltemp[MAXLINE];
1.230     brouard  10910:   char resultline[MAXLINE];
                   10911:   
1.136     brouard  10912:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10913:   char *tok, *val; /* pathtot */
1.290     brouard  10914:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  10915:   int c,  h , cpt, c2;
1.191     brouard  10916:   int jl=0;
                   10917:   int i1, j1, jk, stepsize=0;
1.194     brouard  10918:   int count=0;
                   10919: 
1.164     brouard  10920:   int *tab; 
1.136     brouard  10921:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  10922:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   10923:   /* double anprojf, mprojf, jprojf; */
                   10924:   /* double jintmean,mintmean,aintmean;   */
                   10925:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   10926:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   10927:   double yrfproj= 10.0; /* Number of years of forward projections */
                   10928:   double yrbproj= 10.0; /* Number of years of backward projections */
                   10929:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  10930:   int mobilav=0,popforecast=0;
1.191     brouard  10931:   int hstepm=0, nhstepm=0;
1.136     brouard  10932:   int agemortsup;
                   10933:   float  sumlpop=0.;
                   10934:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10935:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10936: 
1.191     brouard  10937:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10938:   double ftolpl=FTOL;
                   10939:   double **prlim;
1.217     brouard  10940:   double **bprlim;
1.136     brouard  10941:   double ***param; /* Matrix of parameters */
1.251     brouard  10942:   double ***paramstart; /* Matrix of starting parameter values */
                   10943:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10944:   double **matcov; /* Matrix of covariance */
1.203     brouard  10945:   double **hess; /* Hessian matrix */
1.136     brouard  10946:   double ***delti3; /* Scale */
                   10947:   double *delti; /* Scale */
                   10948:   double ***eij, ***vareij;
                   10949:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10950: 
1.136     brouard  10951:   double *epj, vepp;
1.164     brouard  10952: 
1.273     brouard  10953:   double dateprev1, dateprev2;
1.296     brouard  10954:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   10955:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   10956: 
1.217     brouard  10957: 
1.136     brouard  10958:   double **ximort;
1.145     brouard  10959:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10960:   int *dcwave;
                   10961: 
1.164     brouard  10962:   char z[1]="c";
1.136     brouard  10963: 
                   10964:   /*char  *strt;*/
                   10965:   char strtend[80];
1.126     brouard  10966: 
1.164     brouard  10967: 
1.126     brouard  10968: /*   setlocale (LC_ALL, ""); */
                   10969: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10970: /*   textdomain (PACKAGE); */
                   10971: /*   setlocale (LC_CTYPE, ""); */
                   10972: /*   setlocale (LC_MESSAGES, ""); */
                   10973: 
                   10974:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10975:   rstart_time = time(NULL);  
                   10976:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10977:   start_time = *localtime(&rstart_time);
1.126     brouard  10978:   curr_time=start_time;
1.157     brouard  10979:   /*tml = *localtime(&start_time.tm_sec);*/
                   10980:   /* strcpy(strstart,asctime(&tml)); */
                   10981:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10982: 
                   10983: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10984: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10985: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10986: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10987: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10988: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10989: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10990: /*   strt=asctime(&tmg); */
                   10991: /*   printf("Time(after) =%s",strstart);  */
                   10992: /*  (void) time (&time_value);
                   10993: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10994: *  tm = *localtime(&time_value);
                   10995: *  strstart=asctime(&tm);
                   10996: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10997: */
                   10998: 
                   10999:   nberr=0; /* Number of errors and warnings */
                   11000:   nbwarn=0;
1.184     brouard  11001: #ifdef WIN32
                   11002:   _getcwd(pathcd, size);
                   11003: #else
1.126     brouard  11004:   getcwd(pathcd, size);
1.184     brouard  11005: #endif
1.191     brouard  11006:   syscompilerinfo(0);
1.196     brouard  11007:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11008:   if(argc <=1){
                   11009:     printf("\nEnter the parameter file name: ");
1.205     brouard  11010:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11011:       printf("ERROR Empty parameter file name\n");
                   11012:       goto end;
                   11013:     }
1.126     brouard  11014:     i=strlen(pathr);
                   11015:     if(pathr[i-1]=='\n')
                   11016:       pathr[i-1]='\0';
1.156     brouard  11017:     i=strlen(pathr);
1.205     brouard  11018:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11019:       pathr[i-1]='\0';
1.205     brouard  11020:     }
                   11021:     i=strlen(pathr);
                   11022:     if( i==0 ){
                   11023:       printf("ERROR Empty parameter file name\n");
                   11024:       goto end;
                   11025:     }
                   11026:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11027:       printf("Pathr |%s|\n",pathr);
                   11028:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11029:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11030:       strcpy (pathtot, val);
                   11031:       if(pathr[0] == '\0') break; /* Dirty */
                   11032:     }
                   11033:   }
1.281     brouard  11034:   else if (argc<=2){
                   11035:     strcpy(pathtot,argv[1]);
                   11036:   }
1.126     brouard  11037:   else{
                   11038:     strcpy(pathtot,argv[1]);
1.281     brouard  11039:     strcpy(z,argv[2]);
                   11040:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11041:   }
                   11042:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11043:   /*cygwin_split_path(pathtot,path,optionfile);
                   11044:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11045:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11046: 
                   11047:   /* Split argv[0], imach program to get pathimach */
                   11048:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11049:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11050:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11051:  /*   strcpy(pathimach,argv[0]); */
                   11052:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11053:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11054:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11055: #ifdef WIN32
                   11056:   _chdir(path); /* Can be a relative path */
                   11057:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11058: #else
1.126     brouard  11059:   chdir(path); /* Can be a relative path */
1.184     brouard  11060:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11061: #endif
                   11062:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11063:   strcpy(command,"mkdir ");
                   11064:   strcat(command,optionfilefiname);
                   11065:   if((outcmd=system(command)) != 0){
1.169     brouard  11066:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11067:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11068:     /* fclose(ficlog); */
                   11069: /*     exit(1); */
                   11070:   }
                   11071: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11072: /*     perror("mkdir"); */
                   11073: /*   } */
                   11074: 
                   11075:   /*-------- arguments in the command line --------*/
                   11076: 
1.186     brouard  11077:   /* Main Log file */
1.126     brouard  11078:   strcat(filelog, optionfilefiname);
                   11079:   strcat(filelog,".log");    /* */
                   11080:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11081:     printf("Problem with logfile %s\n",filelog);
                   11082:     goto end;
                   11083:   }
                   11084:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11085:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11086:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11087:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11088:  path=%s \n\
                   11089:  optionfile=%s\n\
                   11090:  optionfilext=%s\n\
1.156     brouard  11091:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11092: 
1.197     brouard  11093:   syscompilerinfo(1);
1.167     brouard  11094: 
1.126     brouard  11095:   printf("Local time (at start):%s",strstart);
                   11096:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11097:   fflush(ficlog);
                   11098: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11099: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11100: 
                   11101:   /* */
                   11102:   strcpy(fileres,"r");
                   11103:   strcat(fileres, optionfilefiname);
1.201     brouard  11104:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11105:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11106:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11107: 
1.186     brouard  11108:   /* Main ---------arguments file --------*/
1.126     brouard  11109: 
                   11110:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11111:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11112:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11113:     fflush(ficlog);
1.149     brouard  11114:     /* goto end; */
                   11115:     exit(70); 
1.126     brouard  11116:   }
                   11117: 
                   11118:   strcpy(filereso,"o");
1.201     brouard  11119:   strcat(filereso,fileresu);
1.126     brouard  11120:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11121:     printf("Problem with Output resultfile: %s\n", filereso);
                   11122:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11123:     fflush(ficlog);
                   11124:     goto end;
                   11125:   }
1.278     brouard  11126:       /*-------- Rewriting parameter file ----------*/
                   11127:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11128:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11129:   strcat(rfileres,".");    /* */
                   11130:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11131:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11132:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11133:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11134:     fflush(ficlog);
                   11135:     goto end;
                   11136:   }
                   11137:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11138: 
1.278     brouard  11139:                                      
1.126     brouard  11140:   /* Reads comments: lines beginning with '#' */
                   11141:   numlinepar=0;
1.277     brouard  11142:   /* Is it a BOM UTF-8 Windows file? */
                   11143:   /* First parameter line */
1.197     brouard  11144:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11145:     noffset=0;
                   11146:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11147:     {
                   11148:       noffset=noffset+3;
                   11149:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11150:     }
1.302   ! brouard  11151: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
        !          11152:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11153:     {
                   11154:       noffset=noffset+2;
                   11155:       printf("# File is an UTF16BE BOM file\n");
                   11156:     }
                   11157:     else if( line[0] == 0 && line[1] == 0)
                   11158:     {
                   11159:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11160:        noffset=noffset+4;
                   11161:        printf("# File is an UTF16BE BOM file\n");
                   11162:       }
                   11163:     } else{
                   11164:       ;/*printf(" Not a BOM file\n");*/
                   11165:     }
                   11166:   
1.197     brouard  11167:     /* If line starts with a # it is a comment */
1.277     brouard  11168:     if (line[noffset] == '#') {
1.197     brouard  11169:       numlinepar++;
                   11170:       fputs(line,stdout);
                   11171:       fputs(line,ficparo);
1.278     brouard  11172:       fputs(line,ficres);
1.197     brouard  11173:       fputs(line,ficlog);
                   11174:       continue;
                   11175:     }else
                   11176:       break;
                   11177:   }
                   11178:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11179:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11180:     if (num_filled != 5) {
                   11181:       printf("Should be 5 parameters\n");
1.283     brouard  11182:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11183:     }
1.126     brouard  11184:     numlinepar++;
1.197     brouard  11185:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11186:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11187:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11188:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11189:   }
                   11190:   /* Second parameter line */
                   11191:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11192:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11193:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11194:     if (line[0] == '#') {
                   11195:       numlinepar++;
1.283     brouard  11196:       printf("%s",line);
                   11197:       fprintf(ficres,"%s",line);
                   11198:       fprintf(ficparo,"%s",line);
                   11199:       fprintf(ficlog,"%s",line);
1.197     brouard  11200:       continue;
                   11201:     }else
                   11202:       break;
                   11203:   }
1.223     brouard  11204:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11205:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11206:     if (num_filled != 11) {
                   11207:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11208:       printf("but line=%s\n",line);
1.283     brouard  11209:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11210:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11211:     }
1.286     brouard  11212:     if( lastpass > maxwav){
                   11213:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11214:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11215:       fflush(ficlog);
                   11216:       goto end;
                   11217:     }
                   11218:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11219:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11220:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11221:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11222:   }
1.203     brouard  11223:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11224:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11225:   /* Third parameter line */
                   11226:   while(fgets(line, MAXLINE, ficpar)) {
                   11227:     /* If line starts with a # it is a comment */
                   11228:     if (line[0] == '#') {
                   11229:       numlinepar++;
1.283     brouard  11230:       printf("%s",line);
                   11231:       fprintf(ficres,"%s",line);
                   11232:       fprintf(ficparo,"%s",line);
                   11233:       fprintf(ficlog,"%s",line);
1.197     brouard  11234:       continue;
                   11235:     }else
                   11236:       break;
                   11237:   }
1.201     brouard  11238:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11239:     if (num_filled != 1){
1.302   ! brouard  11240:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
        !          11241:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11242:       model[0]='\0';
                   11243:       goto end;
                   11244:     }
                   11245:     else{
                   11246:       if (model[0]=='+'){
                   11247:        for(i=1; i<=strlen(model);i++)
                   11248:          modeltemp[i-1]=model[i];
1.201     brouard  11249:        strcpy(model,modeltemp); 
1.197     brouard  11250:       }
                   11251:     }
1.199     brouard  11252:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11253:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11254:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11255:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11256:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11257:   }
                   11258:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11259:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11260:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11261:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11262:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11263:   fflush(ficlog);
1.190     brouard  11264:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11265:   if(model[0]=='#'){
1.279     brouard  11266:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11267:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11268:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11269:     if(mle != -1){
1.279     brouard  11270:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11271:       exit(1);
                   11272:     }
                   11273:   }
1.126     brouard  11274:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11275:     ungetc(c,ficpar);
                   11276:     fgets(line, MAXLINE, ficpar);
                   11277:     numlinepar++;
1.195     brouard  11278:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11279:       z[0]=line[1];
                   11280:     }
                   11281:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11282:     fputs(line, stdout);
                   11283:     //puts(line);
1.126     brouard  11284:     fputs(line,ficparo);
                   11285:     fputs(line,ficlog);
                   11286:   }
                   11287:   ungetc(c,ficpar);
                   11288: 
                   11289:    
1.290     brouard  11290:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11291:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11292:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11293:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11294:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11295:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11296:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11297:   */
                   11298:   if (strlen(model)>1) 
1.187     brouard  11299:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11300:   else
1.187     brouard  11301:     ncovmodel=2; /* Constant and age */
1.133     brouard  11302:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11303:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11304:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11305:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11306:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11307:     fflush(stdout);
                   11308:     fclose (ficlog);
                   11309:     goto end;
                   11310:   }
1.126     brouard  11311:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11312:   delti=delti3[1][1];
                   11313:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11314:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11315: /* We could also provide initial parameters values giving by simple logistic regression 
                   11316:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11317:       /* for(i=1;i<nlstate;i++){ */
                   11318:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11319:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11320:       /* } */
1.126     brouard  11321:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11322:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11323:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11324:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11325:     fclose (ficparo);
                   11326:     fclose (ficlog);
                   11327:     goto end;
                   11328:     exit(0);
1.220     brouard  11329:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11330:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11331:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11332:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11333:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11334:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11335:     hess=matrix(1,npar,1,npar);
1.220     brouard  11336:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11337:     /* Read guessed parameters */
1.126     brouard  11338:     /* Reads comments: lines beginning with '#' */
                   11339:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11340:       ungetc(c,ficpar);
                   11341:       fgets(line, MAXLINE, ficpar);
                   11342:       numlinepar++;
1.141     brouard  11343:       fputs(line,stdout);
1.126     brouard  11344:       fputs(line,ficparo);
                   11345:       fputs(line,ficlog);
                   11346:     }
                   11347:     ungetc(c,ficpar);
                   11348:     
                   11349:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11350:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11351:     for(i=1; i <=nlstate; i++){
1.234     brouard  11352:       j=0;
1.126     brouard  11353:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11354:        if(jj==i) continue;
                   11355:        j++;
1.292     brouard  11356:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11357:          ungetc(c,ficpar);
                   11358:          fgets(line, MAXLINE, ficpar);
                   11359:          numlinepar++;
                   11360:          fputs(line,stdout);
                   11361:          fputs(line,ficparo);
                   11362:          fputs(line,ficlog);
                   11363:        }
                   11364:        ungetc(c,ficpar);
1.234     brouard  11365:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11366:        if ((i1 != i) || (j1 != jj)){
                   11367:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11368: It might be a problem of design; if ncovcol and the model are correct\n \
                   11369: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11370:          exit(1);
                   11371:        }
                   11372:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11373:        if(mle==1)
                   11374:          printf("%1d%1d",i,jj);
                   11375:        fprintf(ficlog,"%1d%1d",i,jj);
                   11376:        for(k=1; k<=ncovmodel;k++){
                   11377:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11378:          if(mle==1){
                   11379:            printf(" %lf",param[i][j][k]);
                   11380:            fprintf(ficlog," %lf",param[i][j][k]);
                   11381:          }
                   11382:          else
                   11383:            fprintf(ficlog," %lf",param[i][j][k]);
                   11384:          fprintf(ficparo," %lf",param[i][j][k]);
                   11385:        }
                   11386:        fscanf(ficpar,"\n");
                   11387:        numlinepar++;
                   11388:        if(mle==1)
                   11389:          printf("\n");
                   11390:        fprintf(ficlog,"\n");
                   11391:        fprintf(ficparo,"\n");
1.126     brouard  11392:       }
                   11393:     }  
                   11394:     fflush(ficlog);
1.234     brouard  11395:     
1.251     brouard  11396:     /* Reads parameters values */
1.126     brouard  11397:     p=param[1][1];
1.251     brouard  11398:     pstart=paramstart[1][1];
1.126     brouard  11399:     
                   11400:     /* Reads comments: lines beginning with '#' */
                   11401:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11402:       ungetc(c,ficpar);
                   11403:       fgets(line, MAXLINE, ficpar);
                   11404:       numlinepar++;
1.141     brouard  11405:       fputs(line,stdout);
1.126     brouard  11406:       fputs(line,ficparo);
                   11407:       fputs(line,ficlog);
                   11408:     }
                   11409:     ungetc(c,ficpar);
                   11410: 
                   11411:     for(i=1; i <=nlstate; i++){
                   11412:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11413:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11414:        if ( (i1-i) * (j1-j) != 0){
                   11415:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11416:          exit(1);
                   11417:        }
                   11418:        printf("%1d%1d",i,j);
                   11419:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11420:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11421:        for(k=1; k<=ncovmodel;k++){
                   11422:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11423:          printf(" %le",delti3[i][j][k]);
                   11424:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11425:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11426:        }
                   11427:        fscanf(ficpar,"\n");
                   11428:        numlinepar++;
                   11429:        printf("\n");
                   11430:        fprintf(ficparo,"\n");
                   11431:        fprintf(ficlog,"\n");
1.126     brouard  11432:       }
                   11433:     }
                   11434:     fflush(ficlog);
1.234     brouard  11435:     
1.145     brouard  11436:     /* Reads covariance matrix */
1.126     brouard  11437:     delti=delti3[1][1];
1.220     brouard  11438:                
                   11439:                
1.126     brouard  11440:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11441:                
1.126     brouard  11442:     /* Reads comments: lines beginning with '#' */
                   11443:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11444:       ungetc(c,ficpar);
                   11445:       fgets(line, MAXLINE, ficpar);
                   11446:       numlinepar++;
1.141     brouard  11447:       fputs(line,stdout);
1.126     brouard  11448:       fputs(line,ficparo);
                   11449:       fputs(line,ficlog);
                   11450:     }
                   11451:     ungetc(c,ficpar);
1.220     brouard  11452:                
1.126     brouard  11453:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11454:     hess=matrix(1,npar,1,npar);
1.131     brouard  11455:     for(i=1; i <=npar; i++)
                   11456:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11457:                
1.194     brouard  11458:     /* Scans npar lines */
1.126     brouard  11459:     for(i=1; i <=npar; i++){
1.226     brouard  11460:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11461:       if(count != 3){
1.226     brouard  11462:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11463: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11464: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11465:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11466: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11467: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11468:        exit(1);
1.220     brouard  11469:       }else{
1.226     brouard  11470:        if(mle==1)
                   11471:          printf("%1d%1d%d",i1,j1,jk);
                   11472:       }
                   11473:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11474:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11475:       for(j=1; j <=i; j++){
1.226     brouard  11476:        fscanf(ficpar," %le",&matcov[i][j]);
                   11477:        if(mle==1){
                   11478:          printf(" %.5le",matcov[i][j]);
                   11479:        }
                   11480:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11481:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11482:       }
                   11483:       fscanf(ficpar,"\n");
                   11484:       numlinepar++;
                   11485:       if(mle==1)
1.220     brouard  11486:                                printf("\n");
1.126     brouard  11487:       fprintf(ficlog,"\n");
                   11488:       fprintf(ficparo,"\n");
                   11489:     }
1.194     brouard  11490:     /* End of read covariance matrix npar lines */
1.126     brouard  11491:     for(i=1; i <=npar; i++)
                   11492:       for(j=i+1;j<=npar;j++)
1.226     brouard  11493:        matcov[i][j]=matcov[j][i];
1.126     brouard  11494:     
                   11495:     if(mle==1)
                   11496:       printf("\n");
                   11497:     fprintf(ficlog,"\n");
                   11498:     
                   11499:     fflush(ficlog);
                   11500:     
                   11501:   }    /* End of mle != -3 */
1.218     brouard  11502:   
1.186     brouard  11503:   /*  Main data
                   11504:    */
1.290     brouard  11505:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11506:   /* num=lvector(1,n); */
                   11507:   /* moisnais=vector(1,n); */
                   11508:   /* annais=vector(1,n); */
                   11509:   /* moisdc=vector(1,n); */
                   11510:   /* andc=vector(1,n); */
                   11511:   /* weight=vector(1,n); */
                   11512:   /* agedc=vector(1,n); */
                   11513:   /* cod=ivector(1,n); */
                   11514:   /* for(i=1;i<=n;i++){ */
                   11515:   num=lvector(firstobs,lastobs);
                   11516:   moisnais=vector(firstobs,lastobs);
                   11517:   annais=vector(firstobs,lastobs);
                   11518:   moisdc=vector(firstobs,lastobs);
                   11519:   andc=vector(firstobs,lastobs);
                   11520:   weight=vector(firstobs,lastobs);
                   11521:   agedc=vector(firstobs,lastobs);
                   11522:   cod=ivector(firstobs,lastobs);
                   11523:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11524:     num[i]=0;
                   11525:     moisnais[i]=0;
                   11526:     annais[i]=0;
                   11527:     moisdc[i]=0;
                   11528:     andc[i]=0;
                   11529:     agedc[i]=0;
                   11530:     cod[i]=0;
                   11531:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11532:   }
1.290     brouard  11533:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11534:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11535:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11536:   tab=ivector(1,NCOVMAX);
1.144     brouard  11537:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11538:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11539: 
1.136     brouard  11540:   /* Reads data from file datafile */
                   11541:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11542:     goto end;
                   11543: 
                   11544:   /* Calculation of the number of parameters from char model */
1.234     brouard  11545:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11546:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11547:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11548:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11549:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11550:   */
                   11551:   
                   11552:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11553:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11554:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11555:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11556:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11557:   TvarF=ivector(1,NCOVMAX); /*  */
                   11558:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11559:   TvarV=ivector(1,NCOVMAX); /*  */
                   11560:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11561:   TvarA=ivector(1,NCOVMAX); /*  */
                   11562:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11563:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11564:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11565:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11566:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11567:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11568:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11569:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11570:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11571: 
1.230     brouard  11572:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11573:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11574:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11575:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11576:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11577:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11578:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11579:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11580:   */
                   11581:   /* For model-covariate k tells which data-covariate to use but
                   11582:     because this model-covariate is a construction we invent a new column
                   11583:     ncovcol + k1
                   11584:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11585:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11586:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11587:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11588:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11589:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11590:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11591:   */
1.145     brouard  11592:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11593:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11594:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11595:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11596:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11597:                         4 covariates (3 plus signs)
                   11598:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11599:                      */  
1.230     brouard  11600:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11601:                                * individual dummy, fixed or varying:
                   11602:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11603:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11604:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11605:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11606:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11607:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11608:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11609:                                * individual quantitative, fixed or varying:
                   11610:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11611:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11612:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11613: /* Main decodemodel */
                   11614: 
1.187     brouard  11615: 
1.223     brouard  11616:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11617:     goto end;
                   11618: 
1.137     brouard  11619:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11620:     nbwarn++;
                   11621:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11622:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11623:   }
1.136     brouard  11624:     /*  if(mle==1){*/
1.137     brouard  11625:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11626:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11627:   }
                   11628: 
                   11629:     /*-calculation of age at interview from date of interview and age at death -*/
                   11630:   agev=matrix(1,maxwav,1,imx);
                   11631: 
                   11632:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11633:     goto end;
                   11634: 
1.126     brouard  11635: 
1.136     brouard  11636:   agegomp=(int)agemin;
1.290     brouard  11637:   free_vector(moisnais,firstobs,lastobs);
                   11638:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11639:   /* free_matrix(mint,1,maxwav,1,n);
                   11640:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11641:   /* free_vector(moisdc,1,n); */
                   11642:   /* free_vector(andc,1,n); */
1.145     brouard  11643:   /* */
                   11644:   
1.126     brouard  11645:   wav=ivector(1,imx);
1.214     brouard  11646:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11647:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11648:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11649:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11650:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11651:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11652:    
                   11653:   /* Concatenates waves */
1.214     brouard  11654:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11655:      Death is a valid wave (if date is known).
                   11656:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11657:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11658:      and mw[mi+1][i]. dh depends on stepm.
                   11659:   */
                   11660: 
1.126     brouard  11661:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11662:   /* Concatenates waves */
1.145     brouard  11663:  
1.290     brouard  11664:   free_vector(moisdc,firstobs,lastobs);
                   11665:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11666: 
1.126     brouard  11667:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11668:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11669:   ncodemax[1]=1;
1.145     brouard  11670:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11671:   cptcoveff=0;
1.220     brouard  11672:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11673:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11674:   }
                   11675:   
                   11676:   ncovcombmax=pow(2,cptcoveff);
                   11677:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11678:   for(i=1;i<ncovcombmax;i++)
                   11679:     invalidvarcomb[i]=0;
                   11680:   
1.211     brouard  11681:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11682:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11683:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11684:   
1.200     brouard  11685:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11686:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11687:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11688:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11689:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11690:    * (currently 0 or 1) in the data.
                   11691:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11692:    * corresponding modality (h,j).
                   11693:    */
                   11694: 
1.145     brouard  11695:   h=0;
                   11696:   /*if (cptcovn > 0) */
1.126     brouard  11697:   m=pow(2,cptcoveff);
                   11698:  
1.144     brouard  11699:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11700:           * For k=4 covariates, h goes from 1 to m=2**k
                   11701:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11702:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11703:           *     h\k   1     2     3     4
1.143     brouard  11704:           *______________________________  
                   11705:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11706:           *     2     2     1     1     1
                   11707:           *     3 i=2 1     2     1     1
                   11708:           *     4     2     2     1     1
                   11709:           *     5 i=3 1 i=2 1     2     1
                   11710:           *     6     2     1     2     1
                   11711:           *     7 i=4 1     2     2     1
                   11712:           *     8     2     2     2     1
1.197     brouard  11713:           *     9 i=5 1 i=3 1 i=2 1     2
                   11714:           *    10     2     1     1     2
                   11715:           *    11 i=6 1     2     1     2
                   11716:           *    12     2     2     1     2
                   11717:           *    13 i=7 1 i=4 1     2     2    
                   11718:           *    14     2     1     2     2
                   11719:           *    15 i=8 1     2     2     2
                   11720:           *    16     2     2     2     2
1.143     brouard  11721:           */
1.212     brouard  11722:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11723:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11724:      * and the value of each covariate?
                   11725:      * V1=1, V2=1, V3=2, V4=1 ?
                   11726:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11727:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11728:      * In order to get the real value in the data, we use nbcode
                   11729:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11730:      * We are keeping this crazy system in order to be able (in the future?) 
                   11731:      * to have more than 2 values (0 or 1) for a covariate.
                   11732:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11733:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11734:      *              bbbbbbbb
                   11735:      *              76543210     
                   11736:      *   h-1        00000101 (6-1=5)
1.219     brouard  11737:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11738:      *           &
                   11739:      *     1        00000001 (1)
1.219     brouard  11740:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11741:      *          +1= 00000001 =1 
1.211     brouard  11742:      *
                   11743:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11744:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11745:      *    >>k'            11
                   11746:      *          &   00000001
                   11747:      *            = 00000001
                   11748:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11749:      * Reverse h=6 and m=16?
                   11750:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11751:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11752:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11753:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11754:      * V3=decodtabm(14,3,2**4)=2
                   11755:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11756:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11757:      *          &1 000000001
                   11758:      *           = 000000001
                   11759:      *         +1= 000000010 =2
                   11760:      *                  2211
                   11761:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11762:      *                  V3=2
1.220     brouard  11763:                 * codtabm and decodtabm are identical
1.211     brouard  11764:      */
                   11765: 
1.145     brouard  11766: 
                   11767:  free_ivector(Ndum,-1,NCOVMAX);
                   11768: 
                   11769: 
1.126     brouard  11770:     
1.186     brouard  11771:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11772:   strcpy(optionfilegnuplot,optionfilefiname);
                   11773:   if(mle==-3)
1.201     brouard  11774:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11775:   strcat(optionfilegnuplot,".gp");
                   11776: 
                   11777:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11778:     printf("Problem with file %s",optionfilegnuplot);
                   11779:   }
                   11780:   else{
1.204     brouard  11781:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11782:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11783:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11784:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11785:   }
                   11786:   /*  fclose(ficgp);*/
1.186     brouard  11787: 
                   11788: 
                   11789:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11790: 
                   11791:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11792:   if(mle==-3)
1.201     brouard  11793:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11794:   strcat(optionfilehtm,".htm");
                   11795:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11796:     printf("Problem with %s \n",optionfilehtm);
                   11797:     exit(0);
1.126     brouard  11798:   }
                   11799: 
                   11800:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11801:   strcat(optionfilehtmcov,"-cov.htm");
                   11802:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11803:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11804:   }
                   11805:   else{
                   11806:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11807: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11808: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11809:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11810:   }
                   11811: 
1.213     brouard  11812:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11813: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11814: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11815: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11816: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11817: \n\
                   11818: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11819:  <ul><li><h4>Parameter files</h4>\n\
                   11820:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11821:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11822:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11823:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11824:  - Date and time at start: %s</ul>\n",\
                   11825:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11826:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11827:          fileres,fileres,\
                   11828:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11829:   fflush(fichtm);
                   11830: 
                   11831:   strcpy(pathr,path);
                   11832:   strcat(pathr,optionfilefiname);
1.184     brouard  11833: #ifdef WIN32
                   11834:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11835: #else
1.126     brouard  11836:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11837: #endif
                   11838:          
1.126     brouard  11839:   
1.220     brouard  11840:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11841:                 and for any valid combination of covariates
1.126     brouard  11842:      and prints on file fileres'p'. */
1.251     brouard  11843:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11844:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11845: 
                   11846:   fprintf(fichtm,"\n");
1.286     brouard  11847:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11848:          ftol, stepm);
                   11849:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11850:   ncurrv=1;
                   11851:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11852:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11853:   ncurrv=i;
                   11854:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11855:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11856:   ncurrv=i;
                   11857:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11858:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11859:   ncurrv=i;
                   11860:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11861:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11862:           nlstate, ndeath, maxwav, mle, weightopt);
                   11863: 
                   11864:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11865: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11866: 
                   11867:   
                   11868:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11869: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11870: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11871:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11872:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11873:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11874:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11875:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11876:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11877: 
1.126     brouard  11878:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11879:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11880:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11881: 
                   11882:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11883:   /* For mortality only */
1.126     brouard  11884:   if (mle==-3){
1.136     brouard  11885:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11886:     for(i=1;i<=NDIM;i++)
                   11887:       for(j=1;j<=NDIM;j++)
                   11888:        ximort[i][j]=0.;
1.186     brouard  11889:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11890:     cens=ivector(firstobs,lastobs);
                   11891:     ageexmed=vector(firstobs,lastobs);
                   11892:     agecens=vector(firstobs,lastobs);
                   11893:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11894:                
1.126     brouard  11895:     for (i=1; i<=imx; i++){
                   11896:       dcwave[i]=-1;
                   11897:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11898:        if (s[m][i]>nlstate) {
                   11899:          dcwave[i]=m;
                   11900:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11901:          break;
                   11902:        }
1.126     brouard  11903:     }
1.226     brouard  11904:     
1.126     brouard  11905:     for (i=1; i<=imx; i++) {
                   11906:       if (wav[i]>0){
1.226     brouard  11907:        ageexmed[i]=agev[mw[1][i]][i];
                   11908:        j=wav[i];
                   11909:        agecens[i]=1.; 
                   11910:        
                   11911:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11912:          agecens[i]=agev[mw[j][i]][i];
                   11913:          cens[i]= 1;
                   11914:        }else if (ageexmed[i]< 1) 
                   11915:          cens[i]= -1;
                   11916:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11917:          cens[i]=0 ;
1.126     brouard  11918:       }
                   11919:       else cens[i]=-1;
                   11920:     }
                   11921:     
                   11922:     for (i=1;i<=NDIM;i++) {
                   11923:       for (j=1;j<=NDIM;j++)
1.226     brouard  11924:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11925:     }
                   11926:     
1.302   ! brouard  11927:     p[1]=0.0268; p[NDIM]=0.083;
        !          11928:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  11929:     
                   11930:     
1.136     brouard  11931: #ifdef GSL
                   11932:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11933: #else
1.126     brouard  11934:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11935: #endif
1.201     brouard  11936:     strcpy(filerespow,"POW-MORT_"); 
                   11937:     strcat(filerespow,fileresu);
1.126     brouard  11938:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11939:       printf("Problem with resultfile: %s\n", filerespow);
                   11940:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11941:     }
1.136     brouard  11942: #ifdef GSL
                   11943:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11944: #else
1.126     brouard  11945:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11946: #endif
1.126     brouard  11947:     /*  for (i=1;i<=nlstate;i++)
                   11948:        for(j=1;j<=nlstate+ndeath;j++)
                   11949:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11950:     */
                   11951:     fprintf(ficrespow,"\n");
1.136     brouard  11952: #ifdef GSL
                   11953:     /* gsl starts here */ 
                   11954:     T = gsl_multimin_fminimizer_nmsimplex;
                   11955:     gsl_multimin_fminimizer *sfm = NULL;
                   11956:     gsl_vector *ss, *x;
                   11957:     gsl_multimin_function minex_func;
                   11958: 
                   11959:     /* Initial vertex size vector */
                   11960:     ss = gsl_vector_alloc (NDIM);
                   11961:     
                   11962:     if (ss == NULL){
                   11963:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11964:     }
                   11965:     /* Set all step sizes to 1 */
                   11966:     gsl_vector_set_all (ss, 0.001);
                   11967: 
                   11968:     /* Starting point */
1.126     brouard  11969:     
1.136     brouard  11970:     x = gsl_vector_alloc (NDIM);
                   11971:     
                   11972:     if (x == NULL){
                   11973:       gsl_vector_free(ss);
                   11974:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11975:     }
                   11976:   
                   11977:     /* Initialize method and iterate */
                   11978:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11979:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11980:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11981:     gsl_vector_set(x, 0, p[1]);
                   11982:     gsl_vector_set(x, 1, p[2]);
                   11983: 
                   11984:     minex_func.f = &gompertz_f;
                   11985:     minex_func.n = NDIM;
                   11986:     minex_func.params = (void *)&p; /* ??? */
                   11987:     
                   11988:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11989:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11990:     
                   11991:     printf("Iterations beginning .....\n\n");
                   11992:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11993: 
                   11994:     iteri=0;
                   11995:     while (rval == GSL_CONTINUE){
                   11996:       iteri++;
                   11997:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11998:       
                   11999:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12000:       fflush(0);
                   12001:       
                   12002:       if (status) 
                   12003:         break;
                   12004:       
                   12005:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12006:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12007:       
                   12008:       if (rval == GSL_SUCCESS)
                   12009:         printf ("converged to a local maximum at\n");
                   12010:       
                   12011:       printf("%5d ", iteri);
                   12012:       for (it = 0; it < NDIM; it++){
                   12013:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12014:       }
                   12015:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12016:     }
                   12017:     
                   12018:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12019:     
                   12020:     gsl_vector_free(x); /* initial values */
                   12021:     gsl_vector_free(ss); /* inital step size */
                   12022:     for (it=0; it<NDIM; it++){
                   12023:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12024:       fprintf(ficrespow," %.12lf", p[it]);
                   12025:     }
                   12026:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12027: #endif
                   12028: #ifdef POWELL
                   12029:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12030: #endif  
1.126     brouard  12031:     fclose(ficrespow);
                   12032:     
1.203     brouard  12033:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12034: 
                   12035:     for(i=1; i <=NDIM; i++)
                   12036:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12037:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12038:     
                   12039:     printf("\nCovariance matrix\n ");
1.203     brouard  12040:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12041:     for(i=1; i <=NDIM; i++) {
                   12042:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12043:                                printf("%f ",matcov[i][j]);
                   12044:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12045:       }
1.203     brouard  12046:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12047:     }
                   12048:     
                   12049:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12050:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12051:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12052:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12053:     }
1.302   ! brouard  12054:     lsurv=vector(agegomp,AGESUP);
        !          12055:     lpop=vector(agegomp,AGESUP);
        !          12056:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12057:     lsurv[agegomp]=100000;
                   12058:     
                   12059:     for (k=agegomp;k<=AGESUP;k++) {
                   12060:       agemortsup=k;
                   12061:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12062:     }
                   12063:     
                   12064:     for (k=agegomp;k<agemortsup;k++)
                   12065:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12066:     
                   12067:     for (k=agegomp;k<agemortsup;k++){
                   12068:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12069:       sumlpop=sumlpop+lpop[k];
                   12070:     }
                   12071:     
                   12072:     tpop[agegomp]=sumlpop;
                   12073:     for (k=agegomp;k<(agemortsup-3);k++){
                   12074:       /*  tpop[k+1]=2;*/
                   12075:       tpop[k+1]=tpop[k]-lpop[k];
                   12076:     }
                   12077:     
                   12078:     
                   12079:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12080:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12081:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12082:     
                   12083:     
                   12084:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12085:                ageminpar=50;
                   12086:                agemaxpar=100;
1.194     brouard  12087:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12088:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12089: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12090: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12091:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12092: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12093: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12094:     }else{
                   12095:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12096:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12097:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12098:                }
1.201     brouard  12099:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12100:                     stepm, weightopt,\
                   12101:                     model,imx,p,matcov,agemortsup);
                   12102:     
1.302   ! brouard  12103:     free_vector(lsurv,agegomp,AGESUP);
        !          12104:     free_vector(lpop,agegomp,AGESUP);
        !          12105:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12106:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12107:     free_ivector(dcwave,firstobs,lastobs);
                   12108:     free_vector(agecens,firstobs,lastobs);
                   12109:     free_vector(ageexmed,firstobs,lastobs);
                   12110:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12111: #ifdef GSL
1.136     brouard  12112: #endif
1.186     brouard  12113:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12114:   /* Standard  */
                   12115:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12116:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12117:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12118:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12119:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12120:     for (k=1; k<=npar;k++)
                   12121:       printf(" %d %8.5f",k,p[k]);
                   12122:     printf("\n");
1.205     brouard  12123:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12124:       /* mlikeli uses func not funcone */
1.247     brouard  12125:       /* for(i=1;i<nlstate;i++){ */
                   12126:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12127:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12128:       /* } */
1.205     brouard  12129:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12130:     }
                   12131:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12132:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12133:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12134:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12135:     }
                   12136:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12137:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12138:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12139:     for (k=1; k<=npar;k++)
                   12140:       printf(" %d %8.5f",k,p[k]);
                   12141:     printf("\n");
                   12142:     
                   12143:     /*--------- results files --------------*/
1.283     brouard  12144:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12145:     
                   12146:     
                   12147:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12148:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12149:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12150:     for(i=1,jk=1; i <=nlstate; i++){
                   12151:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12152:        if (k != i) {
                   12153:          printf("%d%d ",i,k);
                   12154:          fprintf(ficlog,"%d%d ",i,k);
                   12155:          fprintf(ficres,"%1d%1d ",i,k);
                   12156:          for(j=1; j <=ncovmodel; j++){
                   12157:            printf("%12.7f ",p[jk]);
                   12158:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12159:            fprintf(ficres,"%12.7f ",p[jk]);
                   12160:            jk++; 
                   12161:          }
                   12162:          printf("\n");
                   12163:          fprintf(ficlog,"\n");
                   12164:          fprintf(ficres,"\n");
                   12165:        }
1.126     brouard  12166:       }
                   12167:     }
1.203     brouard  12168:     if(mle != 0){
                   12169:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12170:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12171:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12172:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12173:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12174:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12175:        for(k=1; k <=(nlstate+ndeath); k++){
                   12176:          if (k != i) {
                   12177:            printf("%d%d ",i,k);
                   12178:            fprintf(ficlog,"%d%d ",i,k);
                   12179:            for(j=1; j <=ncovmodel; j++){
                   12180:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12181:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12182:              jk++; 
                   12183:            }
                   12184:            printf("\n");
                   12185:            fprintf(ficlog,"\n");
                   12186:          }
                   12187:        }
1.193     brouard  12188:       }
1.203     brouard  12189:     } /* end of hesscov and Wald tests */
1.225     brouard  12190:     
1.203     brouard  12191:     /*  */
1.126     brouard  12192:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12193:     printf("# Scales (for hessian or gradient estimation)\n");
                   12194:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12195:     for(i=1,jk=1; i <=nlstate; i++){
                   12196:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12197:        if (j!=i) {
                   12198:          fprintf(ficres,"%1d%1d",i,j);
                   12199:          printf("%1d%1d",i,j);
                   12200:          fprintf(ficlog,"%1d%1d",i,j);
                   12201:          for(k=1; k<=ncovmodel;k++){
                   12202:            printf(" %.5e",delti[jk]);
                   12203:            fprintf(ficlog," %.5e",delti[jk]);
                   12204:            fprintf(ficres," %.5e",delti[jk]);
                   12205:            jk++;
                   12206:          }
                   12207:          printf("\n");
                   12208:          fprintf(ficlog,"\n");
                   12209:          fprintf(ficres,"\n");
                   12210:        }
1.126     brouard  12211:       }
                   12212:     }
                   12213:     
                   12214:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12215:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12216:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12217:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12218:     /* # 121 Var(a12)\n\ */
                   12219:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12220:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12221:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12222:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12223:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12224:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12225:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12226:     
                   12227:     
                   12228:     /* Just to have a covariance matrix which will be more understandable
                   12229:        even is we still don't want to manage dictionary of variables
                   12230:     */
                   12231:     for(itimes=1;itimes<=2;itimes++){
                   12232:       jj=0;
                   12233:       for(i=1; i <=nlstate; i++){
1.225     brouard  12234:        for(j=1; j <=nlstate+ndeath; j++){
                   12235:          if(j==i) continue;
                   12236:          for(k=1; k<=ncovmodel;k++){
                   12237:            jj++;
                   12238:            ca[0]= k+'a'-1;ca[1]='\0';
                   12239:            if(itimes==1){
                   12240:              if(mle>=1)
                   12241:                printf("#%1d%1d%d",i,j,k);
                   12242:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12243:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12244:            }else{
                   12245:              if(mle>=1)
                   12246:                printf("%1d%1d%d",i,j,k);
                   12247:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12248:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12249:            }
                   12250:            ll=0;
                   12251:            for(li=1;li <=nlstate; li++){
                   12252:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12253:                if(lj==li) continue;
                   12254:                for(lk=1;lk<=ncovmodel;lk++){
                   12255:                  ll++;
                   12256:                  if(ll<=jj){
                   12257:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12258:                    if(ll<jj){
                   12259:                      if(itimes==1){
                   12260:                        if(mle>=1)
                   12261:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12262:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12263:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12264:                      }else{
                   12265:                        if(mle>=1)
                   12266:                          printf(" %.5e",matcov[jj][ll]); 
                   12267:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12268:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12269:                      }
                   12270:                    }else{
                   12271:                      if(itimes==1){
                   12272:                        if(mle>=1)
                   12273:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12274:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12275:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12276:                      }else{
                   12277:                        if(mle>=1)
                   12278:                          printf(" %.7e",matcov[jj][ll]); 
                   12279:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12280:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12281:                      }
                   12282:                    }
                   12283:                  }
                   12284:                } /* end lk */
                   12285:              } /* end lj */
                   12286:            } /* end li */
                   12287:            if(mle>=1)
                   12288:              printf("\n");
                   12289:            fprintf(ficlog,"\n");
                   12290:            fprintf(ficres,"\n");
                   12291:            numlinepar++;
                   12292:          } /* end k*/
                   12293:        } /*end j */
1.126     brouard  12294:       } /* end i */
                   12295:     } /* end itimes */
                   12296:     
                   12297:     fflush(ficlog);
                   12298:     fflush(ficres);
1.225     brouard  12299:     while(fgets(line, MAXLINE, ficpar)) {
                   12300:       /* If line starts with a # it is a comment */
                   12301:       if (line[0] == '#') {
                   12302:        numlinepar++;
                   12303:        fputs(line,stdout);
                   12304:        fputs(line,ficparo);
                   12305:        fputs(line,ficlog);
1.299     brouard  12306:        fputs(line,ficres);
1.225     brouard  12307:        continue;
                   12308:       }else
                   12309:        break;
                   12310:     }
                   12311:     
1.209     brouard  12312:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12313:     /*   ungetc(c,ficpar); */
                   12314:     /*   fgets(line, MAXLINE, ficpar); */
                   12315:     /*   fputs(line,stdout); */
                   12316:     /*   fputs(line,ficparo); */
                   12317:     /* } */
                   12318:     /* ungetc(c,ficpar); */
1.126     brouard  12319:     
                   12320:     estepm=0;
1.209     brouard  12321:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12322:       
                   12323:       if (num_filled != 6) {
                   12324:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12325:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12326:        goto end;
                   12327:       }
                   12328:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12329:     }
                   12330:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12331:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12332:     
1.209     brouard  12333:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12334:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12335:     if (fage <= 2) {
                   12336:       bage = ageminpar;
                   12337:       fage = agemaxpar;
                   12338:     }
                   12339:     
                   12340:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12341:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12342:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12343:                
1.186     brouard  12344:     /* Other stuffs, more or less useful */    
1.254     brouard  12345:     while(fgets(line, MAXLINE, ficpar)) {
                   12346:       /* If line starts with a # it is a comment */
                   12347:       if (line[0] == '#') {
                   12348:        numlinepar++;
                   12349:        fputs(line,stdout);
                   12350:        fputs(line,ficparo);
                   12351:        fputs(line,ficlog);
1.299     brouard  12352:        fputs(line,ficres);
1.254     brouard  12353:        continue;
                   12354:       }else
                   12355:        break;
                   12356:     }
                   12357: 
                   12358:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12359:       
                   12360:       if (num_filled != 7) {
                   12361:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12362:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12363:        goto end;
                   12364:       }
                   12365:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12366:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12367:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12368:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12369:     }
1.254     brouard  12370: 
                   12371:     while(fgets(line, MAXLINE, ficpar)) {
                   12372:       /* If line starts with a # it is a comment */
                   12373:       if (line[0] == '#') {
                   12374:        numlinepar++;
                   12375:        fputs(line,stdout);
                   12376:        fputs(line,ficparo);
                   12377:        fputs(line,ficlog);
1.299     brouard  12378:        fputs(line,ficres);
1.254     brouard  12379:        continue;
                   12380:       }else
                   12381:        break;
1.126     brouard  12382:     }
                   12383:     
                   12384:     
                   12385:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12386:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12387:     
1.254     brouard  12388:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12389:       if (num_filled != 1) {
                   12390:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12391:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12392:        goto end;
                   12393:       }
                   12394:       printf("pop_based=%d\n",popbased);
                   12395:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12396:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12397:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12398:     }
                   12399:      
1.258     brouard  12400:     /* Results */
                   12401:     nresult=0;
                   12402:     do{
                   12403:       if(!fgets(line, MAXLINE, ficpar)){
                   12404:        endishere=1;
                   12405:        parameterline=14;
                   12406:       }else if (line[0] == '#') {
                   12407:        /* If line starts with a # it is a comment */
1.254     brouard  12408:        numlinepar++;
                   12409:        fputs(line,stdout);
                   12410:        fputs(line,ficparo);
                   12411:        fputs(line,ficlog);
1.299     brouard  12412:        fputs(line,ficres);
1.254     brouard  12413:        continue;
1.258     brouard  12414:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12415:        parameterline=11;
1.296     brouard  12416:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12417:        parameterline=12;
                   12418:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12419:        parameterline=13;
                   12420:       else{
                   12421:        parameterline=14;
1.254     brouard  12422:       }
1.258     brouard  12423:       switch (parameterline){ 
                   12424:       case 11:
1.296     brouard  12425:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12426:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12427:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12428:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12429:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12430:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12431:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12432:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12433:           prvforecast = 1;
                   12434:        } 
                   12435:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.302   ! brouard  12436:          printf("prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
        !          12437:          fprintf(ficlog,"prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
        !          12438:          fprintf(ficres,"prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12439:           prvforecast = 2;
                   12440:        }
                   12441:        else {
                   12442:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12443:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12444:          goto end;
1.258     brouard  12445:        }
1.254     brouard  12446:        break;
1.258     brouard  12447:       case 12:
1.296     brouard  12448:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12449:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12450:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12451:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12452:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12453:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12454:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12455:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12456:           prvbackcast = 1;
                   12457:        } 
                   12458:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.302   ! brouard  12459:          printf("prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
        !          12460:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
        !          12461:          fprintf(ficres,"prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12462:           prvbackcast = 2;
                   12463:        }
                   12464:        else {
                   12465:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12466:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12467:          goto end;
1.258     brouard  12468:        }
1.230     brouard  12469:        break;
1.258     brouard  12470:       case 13:
                   12471:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12472:          if (num_filled == 0){
                   12473:            resultline[0]='\0';
                   12474:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12475:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12476:            break;
                   12477:          } else if (num_filled != 1){
                   12478:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12479:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12480:          }
                   12481:          nresult++; /* Sum of resultlines */
                   12482:          printf("Result %d: result=%s\n",nresult, resultline);
                   12483:          if(nresult > MAXRESULTLINES){
                   12484:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12485:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12486:            goto end;
                   12487:          }
                   12488:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12489:          fprintf(ficparo,"result: %s\n",resultline);
                   12490:          fprintf(ficres,"result: %s\n",resultline);
                   12491:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12492:          break;
1.258     brouard  12493:        case 14: 
1.259     brouard  12494:          if(ncovmodel >2 && nresult==0 ){
                   12495:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12496:            goto end;
                   12497:          }
1.259     brouard  12498:          break;
1.258     brouard  12499:        default:
                   12500:          nresult=1;
                   12501:          decoderesult(".",nresult ); /* No covariate */
                   12502:        }
                   12503:       } /* End switch parameterline */
                   12504:     }while(endishere==0); /* End do */
1.126     brouard  12505:     
1.230     brouard  12506:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12507:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12508:     
                   12509:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12510:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12511:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12512: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12513: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12514:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12515: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12516: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12517:     }else{
1.270     brouard  12518:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12519:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12520:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12521:       if(prvforecast==1){
                   12522:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12523:         jprojd=jproj1;
                   12524:         mprojd=mproj1;
                   12525:         anprojd=anproj1;
                   12526:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12527:         jprojf=jproj2;
                   12528:         mprojf=mproj2;
                   12529:         anprojf=anproj2;
                   12530:       } else if(prvforecast == 2){
                   12531:         dateprojd=dateintmean;
                   12532:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12533:         dateprojf=dateintmean+yrfproj;
                   12534:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12535:       }
                   12536:       if(prvbackcast==1){
                   12537:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12538:         jbackd=jback1;
                   12539:         mbackd=mback1;
                   12540:         anbackd=anback1;
                   12541:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12542:         jbackf=jback2;
                   12543:         mbackf=mback2;
                   12544:         anbackf=anback2;
                   12545:       } else if(prvbackcast == 2){
                   12546:         datebackd=dateintmean;
                   12547:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12548:         datebackf=dateintmean-yrbproj;
                   12549:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12550:       }
                   12551:       
                   12552:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12553:     }
                   12554:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12555:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12556:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12557:                
1.225     brouard  12558:     /*------------ free_vector  -------------*/
                   12559:     /*  chdir(path); */
1.220     brouard  12560:                
1.215     brouard  12561:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12562:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12563:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12564:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12565:     free_lvector(num,firstobs,lastobs);
                   12566:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12567:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12568:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12569:     fclose(ficparo);
                   12570:     fclose(ficres);
1.220     brouard  12571:                
                   12572:                
1.186     brouard  12573:     /* Other results (useful)*/
1.220     brouard  12574:                
                   12575:                
1.126     brouard  12576:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12577:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12578:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12579:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12580:     fclose(ficrespl);
                   12581: 
                   12582:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12583:     /*#include "hpijx.h"*/
                   12584:     hPijx(p, bage, fage);
1.145     brouard  12585:     fclose(ficrespij);
1.227     brouard  12586:     
1.220     brouard  12587:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12588:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12589:     k=1;
1.126     brouard  12590:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12591:     
1.269     brouard  12592:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12593:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12594:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12595:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12596:        for(k=1;k<=ncovcombmax;k++)
                   12597:          probs[i][j][k]=0.;
1.269     brouard  12598:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12599:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12600:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12601:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12602:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12603:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12604:          for(k=1;k<=ncovcombmax;k++)
                   12605:            mobaverages[i][j][k]=0.;
1.219     brouard  12606:       mobaverage=mobaverages;
                   12607:       if (mobilav!=0) {
1.235     brouard  12608:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12609:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12610:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12611:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12612:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12613:        }
1.269     brouard  12614:       } else if (mobilavproj !=0) {
1.235     brouard  12615:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12616:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12617:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12618:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12619:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12620:        }
1.269     brouard  12621:       }else{
                   12622:        printf("Internal error moving average\n");
                   12623:        fflush(stdout);
                   12624:        exit(1);
1.219     brouard  12625:       }
                   12626:     }/* end if moving average */
1.227     brouard  12627:     
1.126     brouard  12628:     /*---------- Forecasting ------------------*/
1.296     brouard  12629:     if(prevfcast==1){ 
                   12630:       /*   /\*    if(stepm ==1){*\/ */
                   12631:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12632:       /*This done previously after freqsummary.*/
                   12633:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   12634:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   12635:       
                   12636:       /* } else if (prvforecast==2){ */
                   12637:       /*   /\*    if(stepm ==1){*\/ */
                   12638:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12639:       /* } */
                   12640:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   12641:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  12642:     }
1.269     brouard  12643: 
1.296     brouard  12644:     /* Prevbcasting */
                   12645:     if(prevbcast==1){
1.219     brouard  12646:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12647:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12648:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12649: 
                   12650:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12651: 
                   12652:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12653: 
1.219     brouard  12654:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12655:       fclose(ficresplb);
                   12656: 
1.222     brouard  12657:       hBijx(p, bage, fage, mobaverage);
                   12658:       fclose(ficrespijb);
1.219     brouard  12659: 
1.296     brouard  12660:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   12661:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   12662:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   12663:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   12664:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   12665:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   12666: 
                   12667:       
1.269     brouard  12668:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12669: 
                   12670:       
1.269     brouard  12671:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12672:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12673:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12674:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  12675:     }    /* end  Prevbcasting */
1.268     brouard  12676:  
1.186     brouard  12677:  
                   12678:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12679: 
1.215     brouard  12680:     free_ivector(wav,1,imx);
                   12681:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12682:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12683:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12684:                
                   12685:                
1.127     brouard  12686:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12687:                
1.201     brouard  12688:     strcpy(filerese,"E_");
                   12689:     strcat(filerese,fileresu);
1.126     brouard  12690:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12691:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12692:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12693:     }
1.208     brouard  12694:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12695:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12696: 
                   12697:     pstamp(ficreseij);
1.219     brouard  12698:                
1.235     brouard  12699:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12700:     if (cptcovn < 1){i1=1;}
                   12701:     
                   12702:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12703:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12704:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12705:        continue;
1.219     brouard  12706:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12707:       printf("\n#****** ");
1.225     brouard  12708:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12709:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12710:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12711:       }
                   12712:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12713:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12714:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12715:       }
                   12716:       fprintf(ficreseij,"******\n");
1.235     brouard  12717:       printf("******\n");
1.219     brouard  12718:       
                   12719:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12720:       oldm=oldms;savm=savms;
1.235     brouard  12721:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12722:       
1.219     brouard  12723:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12724:     }
                   12725:     fclose(ficreseij);
1.208     brouard  12726:     printf("done evsij\n");fflush(stdout);
                   12727:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12728: 
1.218     brouard  12729:                
1.227     brouard  12730:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12731:                
1.201     brouard  12732:     strcpy(filerest,"T_");
                   12733:     strcat(filerest,fileresu);
1.127     brouard  12734:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12735:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12736:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12737:     }
1.208     brouard  12738:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12739:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12740:     strcpy(fileresstde,"STDE_");
                   12741:     strcat(fileresstde,fileresu);
1.126     brouard  12742:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12743:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12744:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12745:     }
1.227     brouard  12746:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12747:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12748: 
1.201     brouard  12749:     strcpy(filerescve,"CVE_");
                   12750:     strcat(filerescve,fileresu);
1.126     brouard  12751:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12752:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12753:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12754:     }
1.227     brouard  12755:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12756:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12757: 
1.201     brouard  12758:     strcpy(fileresv,"V_");
                   12759:     strcat(fileresv,fileresu);
1.126     brouard  12760:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12761:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12762:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12763:     }
1.227     brouard  12764:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12765:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12766: 
1.235     brouard  12767:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12768:     if (cptcovn < 1){i1=1;}
                   12769:     
                   12770:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12771:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12772:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12773:        continue;
1.242     brouard  12774:       printf("\n#****** Result for:");
                   12775:       fprintf(ficrest,"\n#****** Result for:");
                   12776:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12777:       for(j=1;j<=cptcoveff;j++){ 
                   12778:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12779:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12780:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12781:       }
1.235     brouard  12782:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12783:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12784:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12785:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12786:       }        
1.208     brouard  12787:       fprintf(ficrest,"******\n");
1.227     brouard  12788:       fprintf(ficlog,"******\n");
                   12789:       printf("******\n");
1.208     brouard  12790:       
                   12791:       fprintf(ficresstdeij,"\n#****** ");
                   12792:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12793:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12794:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12795:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12796:       }
1.235     brouard  12797:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12798:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12799:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12800:       }        
1.208     brouard  12801:       fprintf(ficresstdeij,"******\n");
                   12802:       fprintf(ficrescveij,"******\n");
                   12803:       
                   12804:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12805:       /* pstamp(ficresvij); */
1.225     brouard  12806:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12807:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12808:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12809:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12810:       }        
1.208     brouard  12811:       fprintf(ficresvij,"******\n");
                   12812:       
                   12813:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12814:       oldm=oldms;savm=savms;
1.235     brouard  12815:       printf(" cvevsij ");
                   12816:       fprintf(ficlog, " cvevsij ");
                   12817:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12818:       printf(" end cvevsij \n ");
                   12819:       fprintf(ficlog, " end cvevsij \n ");
                   12820:       
                   12821:       /*
                   12822:        */
                   12823:       /* goto endfree; */
                   12824:       
                   12825:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12826:       pstamp(ficrest);
                   12827:       
1.269     brouard  12828:       epj=vector(1,nlstate+1);
1.208     brouard  12829:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12830:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12831:        cptcod= 0; /* To be deleted */
                   12832:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12833:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12834:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12835:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12836:        if(vpopbased==1)
                   12837:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12838:        else
1.288     brouard  12839:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12840:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12841:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12842:        fprintf(ficrest,"\n");
                   12843:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12844:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12845:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12846:        for(age=bage; age <=fage ;age++){
1.235     brouard  12847:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12848:          if (vpopbased==1) {
                   12849:            if(mobilav ==0){
                   12850:              for(i=1; i<=nlstate;i++)
                   12851:                prlim[i][i]=probs[(int)age][i][k];
                   12852:            }else{ /* mobilav */ 
                   12853:              for(i=1; i<=nlstate;i++)
                   12854:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12855:            }
                   12856:          }
1.219     brouard  12857:          
1.227     brouard  12858:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12859:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12860:          /* printf(" age %4.0f ",age); */
                   12861:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12862:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12863:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12864:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12865:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12866:            }
                   12867:            epj[nlstate+1] +=epj[j];
                   12868:          }
                   12869:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12870:          
1.227     brouard  12871:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12872:            for(j=1;j <=nlstate;j++)
                   12873:              vepp += vareij[i][j][(int)age];
                   12874:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12875:          for(j=1;j <=nlstate;j++){
                   12876:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12877:          }
                   12878:          fprintf(ficrest,"\n");
                   12879:        }
1.208     brouard  12880:       } /* End vpopbased */
1.269     brouard  12881:       free_vector(epj,1,nlstate+1);
1.208     brouard  12882:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12883:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12884:       printf("done selection\n");fflush(stdout);
                   12885:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12886:       
1.235     brouard  12887:     } /* End k selection */
1.227     brouard  12888: 
                   12889:     printf("done State-specific expectancies\n");fflush(stdout);
                   12890:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12891: 
1.288     brouard  12892:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12893:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12894: 
1.227     brouard  12895:     
1.290     brouard  12896:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12897:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12898:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12899:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12900:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12901:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12902:     free_ivector(tab,1,NCOVMAX);
                   12903:     fclose(ficresstdeij);
                   12904:     fclose(ficrescveij);
                   12905:     fclose(ficresvij);
                   12906:     fclose(ficrest);
                   12907:     fclose(ficpar);
                   12908:     
                   12909:     
1.126     brouard  12910:     /*---------- End : free ----------------*/
1.219     brouard  12911:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12912:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12913:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12914:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12915:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12916:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12917:   /* endfree:*/
                   12918:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12919:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12920:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  12921:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   12922:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   12923:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   12924:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  12925:   free_matrix(matcov,1,npar,1,npar);
                   12926:   free_matrix(hess,1,npar,1,npar);
                   12927:   /*free_vector(delti,1,npar);*/
                   12928:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12929:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12930:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12931:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12932:   
                   12933:   free_ivector(ncodemax,1,NCOVMAX);
                   12934:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12935:   free_ivector(Dummy,-1,NCOVMAX);
                   12936:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12937:   free_ivector(DummyV,1,NCOVMAX);
                   12938:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12939:   free_ivector(Typevar,-1,NCOVMAX);
                   12940:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12941:   free_ivector(TvarsQ,1,NCOVMAX);
                   12942:   free_ivector(TvarsQind,1,NCOVMAX);
                   12943:   free_ivector(TvarsD,1,NCOVMAX);
                   12944:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12945:   free_ivector(TvarFD,1,NCOVMAX);
                   12946:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12947:   free_ivector(TvarF,1,NCOVMAX);
                   12948:   free_ivector(TvarFind,1,NCOVMAX);
                   12949:   free_ivector(TvarV,1,NCOVMAX);
                   12950:   free_ivector(TvarVind,1,NCOVMAX);
                   12951:   free_ivector(TvarA,1,NCOVMAX);
                   12952:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12953:   free_ivector(TvarFQ,1,NCOVMAX);
                   12954:   free_ivector(TvarFQind,1,NCOVMAX);
                   12955:   free_ivector(TvarVD,1,NCOVMAX);
                   12956:   free_ivector(TvarVDind,1,NCOVMAX);
                   12957:   free_ivector(TvarVQ,1,NCOVMAX);
                   12958:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12959:   free_ivector(Tvarsel,1,NCOVMAX);
                   12960:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12961:   free_ivector(Tposprod,1,NCOVMAX);
                   12962:   free_ivector(Tprod,1,NCOVMAX);
                   12963:   free_ivector(Tvaraff,1,NCOVMAX);
                   12964:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12965:   free_ivector(Tage,1,NCOVMAX);
                   12966:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12967:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12968:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12969:   
                   12970:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12971:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12972:   fflush(fichtm);
                   12973:   fflush(ficgp);
                   12974:   
1.227     brouard  12975:   
1.126     brouard  12976:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12977:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12978:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12979:   }else{
                   12980:     printf("End of Imach\n");
                   12981:     fprintf(ficlog,"End of Imach\n");
                   12982:   }
                   12983:   printf("See log file on %s\n",filelog);
                   12984:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12985:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12986:   rend_time = time(NULL);  
                   12987:   end_time = *localtime(&rend_time);
                   12988:   /* tml = *localtime(&end_time.tm_sec); */
                   12989:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12990:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12991:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12992:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12993:   
1.157     brouard  12994:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12995:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12996:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12997:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12998: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12999:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13000:   fclose(fichtm);
                   13001:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13002:   fclose(fichtmcov);
                   13003:   fclose(ficgp);
                   13004:   fclose(ficlog);
                   13005:   /*------ End -----------*/
1.227     brouard  13006:   
1.281     brouard  13007: 
                   13008: /* Executes gnuplot */
1.227     brouard  13009:   
                   13010:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13011: #ifdef WIN32
1.227     brouard  13012:   if (_chdir(pathcd) != 0)
                   13013:     printf("Can't move to directory %s!\n",path);
                   13014:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13015: #else
1.227     brouard  13016:     if(chdir(pathcd) != 0)
                   13017:       printf("Can't move to directory %s!\n", path);
                   13018:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13019: #endif 
1.126     brouard  13020:     printf("Current directory %s!\n",pathcd);
                   13021:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13022:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13023: #ifdef _WIN32
1.126     brouard  13024:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13025: #endif
                   13026:   if(!stat(plotcmd,&info)){
1.158     brouard  13027:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13028:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13029:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13030:     }else
                   13031:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13032: #ifdef __unix
1.126     brouard  13033:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13034:     if(!stat(plotcmd,&info)){
1.158     brouard  13035:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13036:     }else
                   13037:       strcpy(pplotcmd,plotcmd);
                   13038: #endif
                   13039:   }else
                   13040:     strcpy(pplotcmd,plotcmd);
                   13041:   
                   13042:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13043:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13044:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13045:   
1.126     brouard  13046:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13047:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13048:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13049:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13050:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13051:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13052:       strcpy(plotcmd,pplotcmd);
                   13053:     }
1.126     brouard  13054:   }
1.158     brouard  13055:   printf(" Successful, please wait...");
1.126     brouard  13056:   while (z[0] != 'q') {
                   13057:     /* chdir(path); */
1.154     brouard  13058:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13059:     scanf("%s",z);
                   13060: /*     if (z[0] == 'c') system("./imach"); */
                   13061:     if (z[0] == 'e') {
1.158     brouard  13062: #ifdef __APPLE__
1.152     brouard  13063:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13064: #elif __linux
                   13065:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13066: #else
1.152     brouard  13067:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13068: #endif
                   13069:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13070:       system(pplotcmd);
1.126     brouard  13071:     }
                   13072:     else if (z[0] == 'g') system(plotcmd);
                   13073:     else if (z[0] == 'q') exit(0);
                   13074:   }
1.227     brouard  13075: end:
1.126     brouard  13076:   while (z[0] != 'q') {
1.195     brouard  13077:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13078:     scanf("%s",z);
                   13079:   }
1.283     brouard  13080:   printf("End\n");
1.282     brouard  13081:   exit(0);
1.126     brouard  13082: }

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